1 00:00:02,440 --> 00:00:15,640 Speaker 1: Bloomberg Audio Studios, Podcasts, Radio News. 2 00:00:17,840 --> 00:00:21,520 Speaker 2: Hello and welcome to another episode of The Odd Lots podcast. 3 00:00:21,600 --> 00:00:23,840 Speaker 3: I'm Jolle Wisenthal and I'm Tracy Alloway. 4 00:00:24,120 --> 00:00:26,079 Speaker 2: Tracy, I was gonna ask you a question, but I 5 00:00:26,120 --> 00:00:28,600 Speaker 2: already know the answer to it. I was going to say, like, oh, 6 00:00:28,640 --> 00:00:30,400 Speaker 2: have you ever tried adderall? But I already know you're not, 7 00:00:30,440 --> 00:00:32,600 Speaker 2: so I don't want to like fake the intro whatever, 8 00:00:32,760 --> 00:00:35,159 Speaker 2: but I'm just curious, like, what percentage of our colleagues 9 00:00:35,200 --> 00:00:39,320 Speaker 2: do you think use some sort of stimulant adderall something, 10 00:00:39,400 --> 00:00:42,960 Speaker 2: some sort of performance enhancing workplace. 11 00:00:42,440 --> 00:00:46,520 Speaker 3: Drug like coffee, No, something a little stronger than college. Okay, 12 00:00:47,120 --> 00:00:50,479 Speaker 3: We've had this conversation before, and I think it's such 13 00:00:50,520 --> 00:00:53,800 Speaker 3: an interesting one because, as you know, I have never 14 00:00:53,840 --> 00:00:58,600 Speaker 3: tried adderall. It is a complete cultural blind spot for me. 15 00:00:59,280 --> 00:01:02,240 Speaker 3: But I am one hundred percent sure that you and I, 16 00:01:02,520 --> 00:01:05,480 Speaker 3: in the context of this podcast and our day to 17 00:01:05,560 --> 00:01:08,600 Speaker 3: day lives, have absolutely spoken to people who have been 18 00:01:08,720 --> 00:01:11,560 Speaker 3: on adderall. In fact, a very famous one springs to 19 00:01:11,600 --> 00:01:14,160 Speaker 3: mind right now. I don't know who you're talking about, 20 00:01:14,319 --> 00:01:16,720 Speaker 3: SBF Sam been Free, There you go, there you go, 21 00:01:17,400 --> 00:01:20,920 Speaker 3: but it is an interesting thought experiment. To think about 22 00:01:20,959 --> 00:01:24,560 Speaker 3: the proportion of people around you, you know, sometimes highly 23 00:01:24,600 --> 00:01:27,880 Speaker 3: productive people who may or may not be on adderall 24 00:01:28,040 --> 00:01:28,880 Speaker 3: or something similar. 25 00:01:29,400 --> 00:01:32,080 Speaker 2: So here's my thought, which is that, like, my big 26 00:01:32,160 --> 00:01:35,559 Speaker 2: fear with adderall is like, I'm not maybe against trying 27 00:01:35,560 --> 00:01:37,640 Speaker 2: it because I don't think I have the most focused 28 00:01:37,640 --> 00:01:39,199 Speaker 2: brain in the world. In fact, I know I don't, 29 00:01:39,200 --> 00:01:41,800 Speaker 2: and I get scartered. I'm worried that I would be 30 00:01:41,880 --> 00:01:44,600 Speaker 2: really productive on it and then for the rest of 31 00:01:44,640 --> 00:01:47,120 Speaker 2: my life be faced with this choice of do you 32 00:01:47,160 --> 00:01:49,160 Speaker 2: want to stay on this drug forever or do you 33 00:01:49,200 --> 00:01:51,560 Speaker 2: just want to go back to your old self knowing 34 00:01:51,920 --> 00:01:54,400 Speaker 2: that you have this other potential state in you. Yes, 35 00:01:54,400 --> 00:01:55,160 Speaker 2: that's my big fear. 36 00:01:55,240 --> 00:01:58,240 Speaker 3: I feel the same way. I am deeply concerned that 37 00:01:58,320 --> 00:02:00,840 Speaker 3: I would start writing a book and be successful at it. No, 38 00:02:01,080 --> 00:02:04,080 Speaker 3: that's a joke, but I think, like to me, it 39 00:02:04,200 --> 00:02:07,880 Speaker 3: opens up kind of interesting questions about fairness and access 40 00:02:08,200 --> 00:02:11,960 Speaker 3: and if someone next to you is getting an edge 41 00:02:12,080 --> 00:02:15,919 Speaker 3: because they either have a prescription that maybe they don't 42 00:02:15,919 --> 00:02:17,520 Speaker 3: need or maybe they do need it, and we can 43 00:02:17,560 --> 00:02:21,480 Speaker 3: get into the degree to which adderall actually is needed 44 00:02:21,480 --> 00:02:25,200 Speaker 3: by the population, or they're accessing it illegally. In one 45 00:02:25,200 --> 00:02:28,000 Speaker 3: way or another. It just opens up like interesting questions. 46 00:02:28,040 --> 00:02:30,080 Speaker 3: But then again, I mean, the person next to you 47 00:02:30,080 --> 00:02:32,560 Speaker 3: can drink ten cups of coffee and that's allowed, right, 48 00:02:32,639 --> 00:02:33,640 Speaker 3: Like you're allowed to do that. 49 00:02:34,000 --> 00:02:36,400 Speaker 2: Yeah, I mean, this is not the Olympics. We're trying 50 00:02:36,400 --> 00:02:39,280 Speaker 2: to all maximize our performance here in the corporate world. 51 00:02:39,520 --> 00:02:41,760 Speaker 2: So I first heard about adderall when I was in 52 00:02:41,880 --> 00:02:44,919 Speaker 2: high school. I graduated in ninety eight, and I wasn't 53 00:02:45,040 --> 00:02:48,560 Speaker 2: like a great student. I got bored a lot in class. 54 00:02:48,919 --> 00:02:51,400 Speaker 2: I've just been scattered. I couldn't focus and such, And 55 00:02:51,480 --> 00:02:55,040 Speaker 2: I feel like I was probably in a slightly different environment. 56 00:02:55,160 --> 00:02:57,160 Speaker 2: Maybe if I had been born a couple of years younger, 57 00:02:57,639 --> 00:03:00,240 Speaker 2: I might have been prescribed it. I think maybe not 58 00:03:00,320 --> 00:03:02,399 Speaker 2: because my parents were hippies and so they didn't really 59 00:03:02,400 --> 00:03:06,160 Speaker 2: believe probably and prescribing drugs for that sort of thing. 60 00:03:06,639 --> 00:03:09,080 Speaker 2: But then you know, sort of this cultural thing. It's like, oh, 61 00:03:09,080 --> 00:03:11,960 Speaker 2: they're giving all these boys. 62 00:03:11,080 --> 00:03:13,720 Speaker 3: Yeah, predominantly boys. I think this is a big issue 63 00:03:13,760 --> 00:03:16,880 Speaker 3: that a lot of women weren't diagnosed when they were young, 64 00:03:16,919 --> 00:03:18,799 Speaker 3: and there are a lot of people right now in 65 00:03:18,840 --> 00:03:21,840 Speaker 3: their thirties and forties who are getting late diagnoses because 66 00:03:21,880 --> 00:03:24,640 Speaker 3: all the symptoms that people were looking out for, were, 67 00:03:24,800 --> 00:03:27,280 Speaker 3: you know, hyperactive boys basically. 68 00:03:27,000 --> 00:03:30,120 Speaker 2: Totally, and so it went from a hyperactive boys in 69 00:03:30,200 --> 00:03:32,600 Speaker 2: high school thing, and then I sort of forgot about 70 00:03:32,600 --> 00:03:34,000 Speaker 2: it for a while. Then I went to college and 71 00:03:34,040 --> 00:03:35,920 Speaker 2: I found that to be a little easier, and then 72 00:03:36,040 --> 00:03:38,600 Speaker 2: like I forgot all about adderall. And then over the 73 00:03:38,640 --> 00:03:42,680 Speaker 2: last several years, what we've seen is prescriptions for adderall 74 00:03:42,960 --> 00:03:47,040 Speaker 2: absolutely explode much more adult use, as you say, people 75 00:03:47,200 --> 00:03:50,440 Speaker 2: finding out later in life that they're diagnosed with ADHD, 76 00:03:50,760 --> 00:03:53,920 Speaker 2: which of course has also led to shortages, which have 77 00:03:53,960 --> 00:03:58,880 Speaker 2: a variety of reasons, some relating to the DEA and manufacturing, 78 00:03:59,040 --> 00:04:02,320 Speaker 2: some just related to the absolute booming in demand. And 79 00:04:02,400 --> 00:04:06,240 Speaker 2: so adderall is just sort of an omnipresent topic of 80 00:04:06,360 --> 00:04:09,320 Speaker 2: conversation and an angst in its owne right. 81 00:04:09,480 --> 00:04:12,040 Speaker 3: Yes, And I am just going to emphasize this again 82 00:04:12,800 --> 00:04:16,599 Speaker 3: cultural blind spot for me. So I'm very interested to 83 00:04:16,760 --> 00:04:20,200 Speaker 3: hear how you know, how it works, what the impact 84 00:04:20,279 --> 00:04:23,600 Speaker 3: might be, and what's driving the boom in usage as 85 00:04:23,600 --> 00:04:24,560 Speaker 3: you mentioned. 86 00:04:24,240 --> 00:04:26,440 Speaker 2: Well, I'm really excited to say we do, in fact 87 00:04:26,560 --> 00:04:30,080 Speaker 2: have the perfect guest, someone I've wanted to talk to 88 00:04:30,440 --> 00:04:33,919 Speaker 2: for a long time on the show. And you know 89 00:04:34,040 --> 00:04:36,360 Speaker 2: someone who recently wrote about it, And so there was 90 00:04:36,400 --> 00:04:40,600 Speaker 2: this great set of essays collected by pioneer works talking 91 00:04:40,600 --> 00:04:43,279 Speaker 2: about the adderall phenomenon from various phenomenons. 92 00:04:43,400 --> 00:04:46,440 Speaker 3: I read all of these in one sitting without the 93 00:04:46,520 --> 00:04:48,240 Speaker 3: use of adderall. They're very, very good. 94 00:04:48,400 --> 00:04:50,520 Speaker 2: They're very good. Everyone should read all of them. But 95 00:04:50,560 --> 00:04:52,360 Speaker 2: I'm really excited. We're going to be talking to one 96 00:04:52,360 --> 00:04:55,960 Speaker 2: of the contributors, Danielle Carr. She's an assistant professor at 97 00:04:56,000 --> 00:04:59,560 Speaker 2: the Institute for Society and Genetics at UCLA, and she's 98 00:04:59,600 --> 00:05:03,320 Speaker 2: a history storian of science and psychology. So hopefully we're 99 00:05:03,360 --> 00:05:05,839 Speaker 2: going to understand how did we get to this point 100 00:05:05,960 --> 00:05:09,800 Speaker 2: and what is widespread adderall consumption? How is it rewiring 101 00:05:09,800 --> 00:05:12,680 Speaker 2: our brains or if not, society. So, Danielle, thank you 102 00:05:12,720 --> 00:05:14,680 Speaker 2: so much for coming on odd lots. 103 00:05:14,480 --> 00:05:16,240 Speaker 4: Thank you so much. It's wonderful to be here. 104 00:05:16,600 --> 00:05:19,200 Speaker 2: Describe your work in general. You had a great New 105 00:05:19,279 --> 00:05:22,320 Speaker 2: York Magazine cover story last year, But talk about like 106 00:05:22,360 --> 00:05:25,000 Speaker 2: sort of your from an academic perspective, like what is 107 00:05:25,080 --> 00:05:27,840 Speaker 2: your focus? How does adderall fit into your broader research 108 00:05:27,880 --> 00:05:28,640 Speaker 2: and work over time? 109 00:05:28,839 --> 00:05:31,560 Speaker 4: So I guess I should say that adderall and tension 110 00:05:31,600 --> 00:05:35,800 Speaker 4: deficit diagnoses are not my specific realm of expertise. My 111 00:05:35,880 --> 00:05:39,080 Speaker 4: dissertation work and now my first book is looking at 112 00:05:39,120 --> 00:05:43,080 Speaker 4: the rise of neural implants a la Elon Musk's neuralink 113 00:05:43,200 --> 00:05:47,200 Speaker 4: to treat psychiatric disorders such as anxiety depression PTSD and 114 00:05:47,240 --> 00:05:50,160 Speaker 4: so on. But I guess more generally my line of 115 00:05:50,200 --> 00:05:54,680 Speaker 4: work is looking at the political, economy and historical emergence 116 00:05:54,800 --> 00:05:59,320 Speaker 4: of different types of experimental psychiatric treatments from the twentieth 117 00:05:59,400 --> 00:06:00,560 Speaker 4: to the twenty four century. 118 00:06:01,480 --> 00:06:03,839 Speaker 3: I have a really basic question to start out with, 119 00:06:04,160 --> 00:06:08,280 Speaker 3: what happened to Riddlin? So no, but honestly, so if 120 00:06:08,320 --> 00:06:11,240 Speaker 3: we had been having this discussion in like the nineteen 121 00:06:11,320 --> 00:06:13,479 Speaker 3: nineties or the early two thousands, I don't think we'd 122 00:06:13,520 --> 00:06:15,440 Speaker 3: be talking about adderall. We'd be talking about Riddlin. 123 00:06:15,920 --> 00:06:18,560 Speaker 4: Yeah, I think that that's absolutely right. I mean, one 124 00:06:18,600 --> 00:06:21,400 Speaker 4: of the interesting things to note about the sort of 125 00:06:21,440 --> 00:06:26,200 Speaker 4: cluster of names for this behavioral disorder that is, you know, 126 00:06:26,279 --> 00:06:29,880 Speaker 4: currently called ADD or ADHD, is that there have been 127 00:06:29,920 --> 00:06:33,120 Speaker 4: since nineteen oh two about twenty different names for this 128 00:06:33,240 --> 00:06:38,159 Speaker 4: kind of cluster of syndromes. And so Riddlin emerged as 129 00:06:37,960 --> 00:06:42,440 Speaker 4: it's methyl fenidate rather than an amphetamine, so it's slightly 130 00:06:42,760 --> 00:06:46,200 Speaker 4: different pharmacologically, And it was formulated in the mid nineteen 131 00:06:46,240 --> 00:06:50,040 Speaker 4: fifties as what was hypothesized to be a less addictive 132 00:06:50,240 --> 00:06:53,840 Speaker 4: alternative to amphetamines, which were at that time being used 133 00:06:53,839 --> 00:06:58,040 Speaker 4: to treat children with what was being called hyperkinesis Concerta, 134 00:06:58,160 --> 00:07:01,200 Speaker 4: by the way, is just methyal fenatic x are. But 135 00:07:01,320 --> 00:07:04,279 Speaker 4: there was a period basically in the nineteen seventies when 136 00:07:04,320 --> 00:07:05,960 Speaker 4: and I'm sure we'll get into this, there was a 137 00:07:06,000 --> 00:07:11,040 Speaker 4: sort of widespread panic over the enormous prevalence of infitamines, 138 00:07:11,120 --> 00:07:14,440 Speaker 4: especially to treat children, and riddlin was sort of preferred 139 00:07:14,920 --> 00:07:17,880 Speaker 4: as an alternative that had fewer side effects allegedly and 140 00:07:17,960 --> 00:07:22,160 Speaker 4: was less addictive allegedly, which accounts for the prevalence of 141 00:07:22,280 --> 00:07:25,720 Speaker 4: Riddlin through the sort of mid nineties, at which point 142 00:07:25,800 --> 00:07:30,360 Speaker 4: there's a switch when Shire Pharmaceuticals acquires Obatral, which is 143 00:07:30,640 --> 00:07:34,640 Speaker 4: rebranded as Adderall, and that's really when the Adderall craze hits. 144 00:07:35,040 --> 00:07:35,360 Speaker 5: Tracy. 145 00:07:35,360 --> 00:07:37,200 Speaker 2: I'm glad you asked that, because I had forgotten all 146 00:07:37,240 --> 00:07:40,160 Speaker 2: about Ridlin. But now that you say it, that's what 147 00:07:40,280 --> 00:07:42,920 Speaker 2: people were talking. They weren't talking about adderall yet when 148 00:07:42,960 --> 00:07:44,840 Speaker 2: I was in high school, but I was aware that 149 00:07:44,880 --> 00:07:47,040 Speaker 2: this was the thing, and like CNN and stuff would 150 00:07:47,080 --> 00:07:50,120 Speaker 2: talk about all these boys being described Ridlin. So I 151 00:07:50,200 --> 00:07:53,280 Speaker 2: mentioned Danielle, I was in high school in the mid nineties. 152 00:07:53,680 --> 00:07:57,640 Speaker 2: What was going on then that suddenly there seemed to 153 00:07:57,680 --> 00:08:00,040 Speaker 2: be this, you know, the first wave, or maybe the 154 00:08:00,040 --> 00:08:02,960 Speaker 2: way you describe it, the second wave of this phenomenon 155 00:08:03,120 --> 00:08:04,880 Speaker 2: of let's get all the boys on Ridlin. 156 00:08:05,480 --> 00:08:05,760 Speaker 5: Yeah. 157 00:08:05,800 --> 00:08:08,160 Speaker 4: So I guess we can start the story in media 158 00:08:08,240 --> 00:08:10,960 Speaker 4: res as it were in the mid nineties. But really 159 00:08:11,040 --> 00:08:13,280 Speaker 4: the work of a historian named Nicholas Rusmussen has I 160 00:08:13,280 --> 00:08:16,240 Speaker 4: think done a very magisterial job in showing that the 161 00:08:16,240 --> 00:08:20,320 Speaker 4: twentieth century was defined in many ways by recurrent waves 162 00:08:20,440 --> 00:08:24,040 Speaker 4: of infatimine use. The first wave really began with the 163 00:08:24,120 --> 00:08:27,280 Speaker 4: rise of infetamine use during the Second World War, and 164 00:08:27,400 --> 00:08:28,920 Speaker 4: we can talk about that if you guys would like. 165 00:08:29,360 --> 00:08:32,240 Speaker 4: But by the mid nineties, one of the major things 166 00:08:32,280 --> 00:08:35,119 Speaker 4: that had happened was a panic in the nineteen seventies, 167 00:08:35,120 --> 00:08:39,680 Speaker 4: a sort of moral panic over the extraordinary prevalence of amphetamines, 168 00:08:39,760 --> 00:08:45,000 Speaker 4: mostly dexidron and benzydrin, that were being prescribed without any 169 00:08:45,040 --> 00:08:48,960 Speaker 4: sort of federal control. It was extraordinarily prevalent across the 170 00:08:49,040 --> 00:08:52,280 Speaker 4: US population, and there really were not very many controls 171 00:08:52,320 --> 00:08:55,640 Speaker 4: at all in terms of how doctors needed to report 172 00:08:55,760 --> 00:09:00,160 Speaker 4: these prescriptions to any sort of federal data collection. And 173 00:09:00,160 --> 00:09:03,720 Speaker 4: so in nineteen seventy one you had Congress tasked deda 174 00:09:04,240 --> 00:09:09,320 Speaker 4: with reclassifying amphetamines as being a schedule to substance, that is, 175 00:09:09,760 --> 00:09:14,840 Speaker 4: prescriptions needed to be reported to a central government administration, 176 00:09:15,040 --> 00:09:18,479 Speaker 4: and there were limits and quotas placed on the quantities 177 00:09:18,480 --> 00:09:21,800 Speaker 4: of mphetamines that could be manufactured and then distributed to 178 00:09:21,960 --> 00:09:25,640 Speaker 4: pharmaceutical companies, and so used to have this sort of 179 00:09:26,040 --> 00:09:29,160 Speaker 4: moral panic around that that actually led to a congressional 180 00:09:29,200 --> 00:09:32,040 Speaker 4: investigation in nineteen seventy and there was this sort of 181 00:09:32,440 --> 00:09:36,360 Speaker 4: broader crackdown both legally in the nineteen seventies and also 182 00:09:36,440 --> 00:09:39,840 Speaker 4: culturally where you had like the sort of countercultural figures 183 00:09:39,960 --> 00:09:43,079 Speaker 4: decrying speed freaks, which had also you know, there was 184 00:09:43,120 --> 00:09:45,520 Speaker 4: this discourse in this narrative that for instance, like the 185 00:09:45,559 --> 00:09:47,839 Speaker 4: heighth Atsbury sort of summer of love had been that 186 00:09:47,920 --> 00:09:50,040 Speaker 4: had been destroyed by speed freaks and so on and 187 00:09:50,160 --> 00:09:52,600 Speaker 4: so forth, and so in the nineteen seventies you have 188 00:09:52,679 --> 00:09:57,400 Speaker 4: a movement away from amphetamines proper, which a creates the 189 00:09:57,520 --> 00:10:00,920 Speaker 4: conditions for the rise of things like ritilin, which is 190 00:10:01,000 --> 00:10:04,800 Speaker 4: a methyl feenadate, which is you know, it's pharmacologically quite similar, 191 00:10:04,840 --> 00:10:07,800 Speaker 4: but it was not subject to exactly the same controls 192 00:10:07,840 --> 00:10:11,120 Speaker 4: as emphetamines. And secondly, I think the thing, the very 193 00:10:11,120 --> 00:10:13,679 Speaker 4: important thing that happens is that one of the few 194 00:10:13,960 --> 00:10:19,040 Speaker 4: medical uses for which amphetamines are going into the late 195 00:10:19,120 --> 00:10:22,400 Speaker 4: nineteen seventy is still allowed to be prescribed are child 196 00:10:22,520 --> 00:10:26,800 Speaker 4: behavioral disorders. Now, prior to nineteen seventy and fetamines had 197 00:10:26,800 --> 00:10:29,920 Speaker 4: been used off label for everything from weight loss to 198 00:10:30,320 --> 00:10:34,120 Speaker 4: mood to just like a variety of off label prescriptions. 199 00:10:34,360 --> 00:10:37,439 Speaker 4: But you have this sort of concentration after this crackdown 200 00:10:37,559 --> 00:10:42,160 Speaker 4: by the DEA to focus amphetamine use medically specifically on 201 00:10:42,200 --> 00:10:47,160 Speaker 4: this you know, small cluster of childhood behavioral disorders. This 202 00:10:47,200 --> 00:10:48,640 Speaker 4: sets us up for, by the time we get to 203 00:10:48,640 --> 00:10:52,520 Speaker 4: the nineteen nineties, the sort of growing market for childhood 204 00:10:52,960 --> 00:10:56,160 Speaker 4: applications for m ffetamines. And I guess like the third 205 00:10:56,320 --> 00:11:00,559 Speaker 4: intervening factor here would be that in nineteen teen eighty 206 00:11:00,720 --> 00:11:04,160 Speaker 4: there was the third publication of the Diagnostic and statistical Manual, 207 00:11:04,200 --> 00:11:07,800 Speaker 4: which is the DSM, which is widely described as psychiatry's 208 00:11:07,840 --> 00:11:12,200 Speaker 4: diagnostic bible. This is essentially the list of diagnoses held 209 00:11:12,200 --> 00:11:15,679 Speaker 4: to be medically viable that insurers will agree to cover, 210 00:11:15,960 --> 00:11:18,839 Speaker 4: that clinical trials will investigate, and so on and so forth. 211 00:11:19,200 --> 00:11:24,480 Speaker 4: And add attention deficit disorder is installed in that version 212 00:11:24,559 --> 00:11:27,400 Speaker 4: of the DSM, and so I think this really sets 213 00:11:27,400 --> 00:11:30,439 Speaker 4: the stage for the rise of ADD as a clinical 214 00:11:30,600 --> 00:11:33,960 Speaker 4: diagnostic entity that receives a lot of research funding in 215 00:11:33,960 --> 00:11:37,240 Speaker 4: the nineteen eighties, such that by the nineteen nineties, once 216 00:11:37,280 --> 00:11:39,640 Speaker 4: adderall comes onto the market, the stage is set for 217 00:11:39,679 --> 00:11:43,480 Speaker 4: a very wide sudden uptick in adderall prescriptions for children. 218 00:11:59,160 --> 00:12:02,600 Speaker 3: So talk to us about what adderall actually does. And 219 00:12:02,800 --> 00:12:06,559 Speaker 3: here I have to confess. In preparation for this conversation, 220 00:12:06,720 --> 00:12:09,240 Speaker 3: I walked around Union Square in New York and ask 221 00:12:09,280 --> 00:12:10,720 Speaker 3: people why they take adderall. 222 00:12:10,760 --> 00:12:10,840 Speaker 4: No. 223 00:12:10,920 --> 00:12:13,960 Speaker 3: I asked some people that I know about adderall, and 224 00:12:14,040 --> 00:12:17,000 Speaker 3: someone explained it to me as this idea that if 225 00:12:17,000 --> 00:12:20,960 Speaker 3: you do have ADHD, then you don't have the normal 226 00:12:21,280 --> 00:12:24,760 Speaker 3: level of dopamine in your brain, or your brain handles 227 00:12:24,800 --> 00:12:28,720 Speaker 3: it slightly differently, and so adderall basically helps to normalize 228 00:12:28,880 --> 00:12:33,680 Speaker 3: dopamine and bring it closer to what a neurotypical person 229 00:12:33,880 --> 00:12:39,240 Speaker 3: might have without medication. Could you maybe explain exactly what 230 00:12:39,360 --> 00:12:43,640 Speaker 3: adderall is doing on someone's brain and the differences between 231 00:12:43,720 --> 00:12:47,000 Speaker 3: someone who's maybe taking it to boost their productivity versus 232 00:12:47,000 --> 00:12:49,600 Speaker 3: someone who's taking it because they have been diagnosed with 233 00:12:49,679 --> 00:12:52,800 Speaker 3: ADHD or something else and they have an actual prescription 234 00:12:52,880 --> 00:12:53,480 Speaker 3: from a doctor. 235 00:12:54,400 --> 00:12:54,720 Speaker 5: Yeah. 236 00:12:54,760 --> 00:12:57,040 Speaker 4: So I think the question of what adderall is and 237 00:12:57,080 --> 00:13:01,000 Speaker 4: what it does neurologically is very connected to the very 238 00:13:01,000 --> 00:13:05,880 Speaker 4: contested and open question of what ADD and ADHD are neurologically. 239 00:13:05,960 --> 00:13:10,240 Speaker 4: So maybe I'll start with what is ADD what is ADHD. Now, 240 00:13:10,320 --> 00:13:13,040 Speaker 4: what you have to understand is that with the emergence 241 00:13:13,120 --> 00:13:16,120 Speaker 4: of the DSM three in nineteen eighty, this was a 242 00:13:16,160 --> 00:13:19,440 Speaker 4: document that was created essentially to bring together a bunch 243 00:13:19,480 --> 00:13:22,760 Speaker 4: of different stakeholders under a very large tent. These stakeholders 244 00:13:22,800 --> 00:13:28,600 Speaker 4: included insurers, clinical researchers, formalcological companies of course, and of 245 00:13:28,600 --> 00:13:35,000 Speaker 4: course patients and doctors. And the DSM describes clusters of symptoms, 246 00:13:35,280 --> 00:13:39,400 Speaker 4: that is, syndromes that tend to occur together. So, for instance, 247 00:13:39,880 --> 00:13:44,160 Speaker 4: here's a list of ten to twelve behavioral manifestations that 248 00:13:44,280 --> 00:13:47,319 Speaker 4: tend to cluster together and we're going to call that depression, 249 00:13:47,600 --> 00:13:50,240 Speaker 4: so on and so forth. But particularly in nineteen eighty, 250 00:13:50,280 --> 00:13:54,080 Speaker 4: there was not a robust sense of what the neurological 251 00:13:54,200 --> 00:13:58,640 Speaker 4: underpinning of each of these diagnoses were. These were descriptions 252 00:13:59,080 --> 00:14:03,880 Speaker 4: behaviorally of how these syndromes manifest that were presumed to 253 00:14:03,960 --> 00:14:07,240 Speaker 4: be disease entities. But I mean, if you ask anyone 254 00:14:07,320 --> 00:14:09,720 Speaker 4: working at the cutting edge of sort of neurology psychiatry 255 00:14:09,800 --> 00:14:11,480 Speaker 4: right now, they will tell you quite frankly, that there 256 00:14:11,520 --> 00:14:14,880 Speaker 4: is no guarantee that any one case of let's say, 257 00:14:14,920 --> 00:14:20,200 Speaker 4: depression or anxiety neurologically looks like any other case of 258 00:14:20,280 --> 00:14:23,080 Speaker 4: depression or anxiety. That's because there are many different ways 259 00:14:23,080 --> 00:14:25,480 Speaker 4: to have depressions. Some people might be crying a lot 260 00:14:25,520 --> 00:14:27,600 Speaker 4: and not eating very much. Someone else might not be 261 00:14:27,640 --> 00:14:30,640 Speaker 4: crying very much and eating a lot, for instance, right, 262 00:14:30,680 --> 00:14:34,960 Speaker 4: and so there's no guarantee that each instance of the 263 00:14:35,000 --> 00:14:37,560 Speaker 4: disease entity is going to have the same sort of 264 00:14:38,080 --> 00:14:43,360 Speaker 4: biological underpinning behind it. Now, this works fine for things 265 00:14:43,400 --> 00:14:46,480 Speaker 4: like insurance markets or billing insurers, or sort of getting 266 00:14:46,480 --> 00:14:48,520 Speaker 4: medicine done in a sort of day to day sense, 267 00:14:48,560 --> 00:14:51,520 Speaker 4: But once it comes to sort of extrapolating and understanding 268 00:14:51,520 --> 00:14:54,800 Speaker 4: the neurological basis of diseases, the system does sort of 269 00:14:54,920 --> 00:14:58,160 Speaker 4: fall apart. This is why increasingly clinical research is moving 270 00:14:58,200 --> 00:15:02,440 Speaker 4: towards the ICD system rather than the DSM system. So 271 00:15:02,680 --> 00:15:05,520 Speaker 4: this is neither here nor there, perhaps generally, but specifically 272 00:15:05,520 --> 00:15:07,920 Speaker 4: when it comes to add and ADHD, I think it's 273 00:15:08,000 --> 00:15:10,800 Speaker 4: very important to keep in mind that there is no 274 00:15:11,120 --> 00:15:17,400 Speaker 4: widely accepted, beyond contestation understanding of what these disease entities 275 00:15:17,440 --> 00:15:22,880 Speaker 4: actually are on a neurobiological basis. So there are theories 276 00:15:23,080 --> 00:15:27,560 Speaker 4: that there's some sort of deficit in dopamine production or 277 00:15:27,560 --> 00:15:31,080 Speaker 4: the rear partake of nopernepherin and dopamine. But I think 278 00:15:31,120 --> 00:15:34,680 Speaker 4: it's important to keep in mind that these explanations they 279 00:15:34,760 --> 00:15:37,360 Speaker 4: might be having prevalence now. But if you think about 280 00:15:37,400 --> 00:15:40,760 Speaker 4: the rise of, for instance, the serotonin hypothesis when it 281 00:15:40,800 --> 00:15:45,760 Speaker 4: comes to depression, the serotonin hypothesis dominated theories of depression 282 00:15:46,040 --> 00:15:49,640 Speaker 4: for quite some time and then has been pretty roundly disproven. 283 00:15:49,680 --> 00:15:54,840 Speaker 4: There is not a robust link between depression and serotonin deficits, 284 00:15:55,200 --> 00:15:57,480 Speaker 4: and so I think that's one important thing to keep 285 00:15:57,480 --> 00:16:01,160 Speaker 4: in mind, is that we don't necessarily have a robust 286 00:16:01,280 --> 00:16:05,800 Speaker 4: and agreed upon understanding of what this disease entity quote 287 00:16:05,840 --> 00:16:09,520 Speaker 4: unquote actually is. Now when it comes to what it 288 00:16:09,640 --> 00:16:13,200 Speaker 4: is that stimulants actually do in the brain, the brain 289 00:16:13,240 --> 00:16:17,920 Speaker 4: releases neurotransmitters that then sort of hang out in the 290 00:16:18,040 --> 00:16:20,920 Speaker 4: space in the sort of synaptic space between the axon 291 00:16:21,000 --> 00:16:25,080 Speaker 4: and the dendrite and then are reabsorbed. So neurotransmitters are 292 00:16:25,080 --> 00:16:28,360 Speaker 4: things like, for instance, nopernethyrine, dopamine. Right there's these are 293 00:16:28,360 --> 00:16:31,480 Speaker 4: things that your listeners probably have already heard of. Something 294 00:16:31,760 --> 00:16:36,680 Speaker 4: like an amphetamine decreases the amount of those neurotransmitters that 295 00:16:36,720 --> 00:16:40,000 Speaker 4: are re uptaken, meaning that the sort of synapse is 296 00:16:40,080 --> 00:16:43,640 Speaker 4: bathed for a longer period of time by those chemicals. 297 00:16:44,160 --> 00:16:47,680 Speaker 4: So that's how an amphetamine works, is that it really 298 00:16:47,840 --> 00:16:51,680 Speaker 4: bathes the brain. In dopamine no reprodefron. Dopamine is sort 299 00:16:51,720 --> 00:16:55,560 Speaker 4: of widely theorized or described as being a chemical that 300 00:16:55,640 --> 00:16:59,120 Speaker 4: codes for expectation of reward. So one way that I 301 00:16:59,240 --> 00:17:00,680 Speaker 4: like to explain this is that if you go to 302 00:17:00,680 --> 00:17:03,840 Speaker 4: a gumball and you're expecting to get one gumball, but 303 00:17:03,880 --> 00:17:06,280 Speaker 4: the machine gives you two for one quarter, you're going 304 00:17:06,359 --> 00:17:10,199 Speaker 4: to have a huge dopamine spike because that reward is 305 00:17:10,320 --> 00:17:13,119 Speaker 4: double what you were expecting. And when you think about 306 00:17:13,160 --> 00:17:17,359 Speaker 4: the way that, for instance, addictive technologies like video gambling 307 00:17:17,600 --> 00:17:22,400 Speaker 4: or social media work, they work by introducing variable rewards 308 00:17:22,800 --> 00:17:27,840 Speaker 4: that hook into this very very motivating dopaminergic system in 309 00:17:27,880 --> 00:17:31,800 Speaker 4: the brain. No Ropernaffron similarly controls the body's sort of 310 00:17:31,840 --> 00:17:34,879 Speaker 4: readiness for fight or flight, and so it sort of 311 00:17:35,160 --> 00:17:39,439 Speaker 4: generally increases a feeling of alertness and readiness. But this 312 00:17:39,600 --> 00:17:42,560 Speaker 4: is why you know, it feels really really good to 313 00:17:42,640 --> 00:17:45,320 Speaker 4: be on amphetamines, and it sort of increases this general 314 00:17:45,359 --> 00:17:49,040 Speaker 4: sense of well being and alertness. And indeed, this is 315 00:17:49,040 --> 00:17:52,080 Speaker 4: why you know in the early nineteen thirties, am fetamine 316 00:17:52,119 --> 00:17:55,680 Speaker 4: was widely prescribed for antedonia or a lack of pleasure. 317 00:17:55,760 --> 00:17:59,359 Speaker 4: In fact, historian Nicholas Rismusin has made the case convincingly. 318 00:17:59,400 --> 00:18:02,639 Speaker 4: I think that empetamine was in fact the first antidepressant. 319 00:18:02,640 --> 00:18:06,920 Speaker 4: But at a neurological level, that is essentially what amphetamines 320 00:18:06,920 --> 00:18:10,120 Speaker 4: are doing. They also, because of their dopaminergic action, they 321 00:18:10,160 --> 00:18:14,560 Speaker 4: increase the rewardingness of a task. It is a common 322 00:18:14,640 --> 00:18:19,240 Speaker 4: talking point for sort of ADHD advocates that amphetamines only 323 00:18:19,359 --> 00:18:24,080 Speaker 4: work if you indeed have add or ADHD, and unfortunately 324 00:18:24,280 --> 00:18:28,680 Speaker 4: this is simply not true. Anyone who takes amphetamines has 325 00:18:28,800 --> 00:18:32,440 Speaker 4: this burst in heart rate, burst in feelings of well being, 326 00:18:32,760 --> 00:18:36,480 Speaker 4: burst in ability to concentrate. This has been documented clinically 327 00:18:36,560 --> 00:18:39,679 Speaker 4: over and over again that there's not really a perceptible 328 00:18:39,720 --> 00:18:43,520 Speaker 4: difference between people who have been diagnosed with add or 329 00:18:43,560 --> 00:18:46,600 Speaker 4: ADHD and people who have not when they take these drugs. 330 00:18:47,000 --> 00:18:50,520 Speaker 2: So someone like myself who sometimes worries that maybe I 331 00:18:50,680 --> 00:18:54,640 Speaker 2: have another level of productivity above me, even I've never 332 00:18:54,680 --> 00:18:58,399 Speaker 2: been diagnosed with anything, like, maybe that's true. So you know, 333 00:18:58,480 --> 00:19:01,040 Speaker 2: I get like, as you say, okay, it makes internet 334 00:19:01,080 --> 00:19:05,479 Speaker 2: gambling you could see or tweeting, tweeting, et cetera. But like, 335 00:19:05,800 --> 00:19:07,879 Speaker 2: what is the theory by which like a bunch of 336 00:19:07,880 --> 00:19:11,280 Speaker 2: people who have jobs where they have to make powerpoints 337 00:19:11,320 --> 00:19:14,840 Speaker 2: about some m and a deal and they're all many 338 00:19:14,880 --> 00:19:19,040 Speaker 2: of them apparently on adderall. Like for that person they 339 00:19:19,080 --> 00:19:22,440 Speaker 2: have a job, they're in the office until eleven pm, 340 00:19:22,760 --> 00:19:24,680 Speaker 2: they get one TYPEO wrong, they have to start it 341 00:19:24,720 --> 00:19:27,560 Speaker 2: all over. What does ederall do for them in the 342 00:19:27,920 --> 00:19:30,119 Speaker 2: sort of corporate context or the work context. 343 00:19:30,440 --> 00:19:32,320 Speaker 4: So one of the things that I discussed in my 344 00:19:32,520 --> 00:19:37,440 Speaker 4: essay was clinical literature around what psychiatrists call punding, which 345 00:19:37,480 --> 00:19:41,840 Speaker 4: is repetitive behavioral loops that are often observed in patients 346 00:19:41,840 --> 00:19:45,560 Speaker 4: that are taking drugs that bathe the brain in dopinergic chemicals. 347 00:19:45,840 --> 00:19:49,880 Speaker 4: So punding was first described in the nineteen seventies by 348 00:19:49,880 --> 00:19:53,320 Speaker 4: a psychiatrist who was observing the sort of repetitive behavioral 349 00:19:53,320 --> 00:19:58,199 Speaker 4: loops like tweezing your eyebrows, or sorting and handling objects, 350 00:19:58,440 --> 00:20:01,239 Speaker 4: or hunting for things or collecting things, so on and 351 00:20:01,240 --> 00:20:04,760 Speaker 4: so forth in patients who are taking levadopa, which is 352 00:20:04,760 --> 00:20:08,320 Speaker 4: a dopamine replacement that is used in patients with Parkinson's. 353 00:20:08,920 --> 00:20:11,920 Speaker 4: And I think that this gives us a pretty interesting 354 00:20:12,040 --> 00:20:16,360 Speaker 4: angle into what it is exactly that amphetamines do, which 355 00:20:16,400 --> 00:20:21,160 Speaker 4: is to make these repetitive tasks much much more rewarding 356 00:20:21,240 --> 00:20:23,400 Speaker 4: than they would otherwise be. And so, when you think 357 00:20:23,400 --> 00:20:26,199 Speaker 4: about the forms of work that predominate in the so 358 00:20:26,359 --> 00:20:29,879 Speaker 4: called knowledge economy, right where you're on a computer looking 359 00:20:29,920 --> 00:20:34,520 Speaker 4: for things, searching for information, organizing information, so on and so forth. 360 00:20:35,080 --> 00:20:37,800 Speaker 4: First of all, and amfetamine makes any task that you're 361 00:20:37,800 --> 00:20:41,520 Speaker 4: engaged in much more rewarding because it's massively ramping up 362 00:20:41,600 --> 00:20:44,560 Speaker 4: the dopamine signals in your brain that are telling you 363 00:20:44,840 --> 00:20:47,160 Speaker 4: keep doing this. This thing that you're doing is better 364 00:20:47,160 --> 00:20:49,600 Speaker 4: and better and better than you expected. But I think 365 00:20:49,600 --> 00:20:53,199 Speaker 4: that what's interesting about the role of emphetamine specifically in 366 00:20:53,280 --> 00:20:56,439 Speaker 4: sort of knowledge work is that it makes these repetitive 367 00:20:56,480 --> 00:20:59,960 Speaker 4: tasks feel more like hunting and gathering. Right, It's more 368 00:21:00,040 --> 00:21:04,880 Speaker 4: or it's a more exciting task to do these repetitive tasks. 369 00:21:05,119 --> 00:21:07,679 Speaker 4: And this is not something that is specific to the 370 00:21:07,720 --> 00:21:11,480 Speaker 4: nineteen nineties. When psychiatrist Abraham Myerson, who is one of 371 00:21:11,520 --> 00:21:17,160 Speaker 4: the first psychiatrists to widely use benzydream for a depressed 372 00:21:17,280 --> 00:21:20,920 Speaker 4: and antidonic patients in the nineteen twenties, his clinical area 373 00:21:20,960 --> 00:21:23,879 Speaker 4: of expertise was the sort of neurosis of what he 374 00:21:23,960 --> 00:21:26,800 Speaker 4: called the brain workers of the upper class. So I 375 00:21:26,840 --> 00:21:29,400 Speaker 4: think that there is, you know, a robust through line 376 00:21:29,440 --> 00:21:33,119 Speaker 4: of amphetamines being used for these emergent forms of work 377 00:21:33,240 --> 00:21:34,880 Speaker 4: in the US. That was great. 378 00:21:34,920 --> 00:21:37,520 Speaker 2: By the way, I never heard punding before you wrote 379 00:21:37,520 --> 00:21:39,520 Speaker 2: about it, but if you go to the Wikipedia page 380 00:21:39,640 --> 00:21:42,000 Speaker 2: for punding, there is a very cute photo of someone 381 00:21:42,040 --> 00:21:44,119 Speaker 2: who has lined up all of their rubber duckies. I 382 00:21:44,200 --> 00:21:47,160 Speaker 2: was just looking in sequence, so I guess that person, 383 00:21:47,520 --> 00:21:50,159 Speaker 2: you know, there you go, must have been very satisfying 384 00:21:50,200 --> 00:21:52,200 Speaker 2: for that person to arrange all of their toys. 385 00:21:52,440 --> 00:21:55,359 Speaker 4: If you think about the sort of phenomenological experience of 386 00:21:55,400 --> 00:21:58,640 Speaker 4: what it is like to be online on adderall or 387 00:21:58,680 --> 00:22:01,280 Speaker 4: to do research on at there is a sort of 388 00:22:01,320 --> 00:22:05,520 Speaker 4: punding like quality to always another real watch, always another 389 00:22:05,600 --> 00:22:08,879 Speaker 4: link to open right, and the sort of punding phenomenon 390 00:22:08,920 --> 00:22:12,000 Speaker 4: I think is definitely one way to describe the addictive 391 00:22:12,040 --> 00:22:15,800 Speaker 4: behavioral loops that are built into this sort of giant 392 00:22:15,880 --> 00:22:18,400 Speaker 4: casino called the Internet that we all live in now. 393 00:22:19,200 --> 00:22:21,239 Speaker 3: So this is one of the reasons we wanted to 394 00:22:21,280 --> 00:22:24,680 Speaker 3: talk to you specifically, because you do write about this 395 00:22:24,800 --> 00:22:28,399 Speaker 3: in your essay. This idea that, Okay, the medication is 396 00:22:28,880 --> 00:22:32,560 Speaker 3: now available and more people can access it, but at 397 00:22:32,560 --> 00:22:35,240 Speaker 3: the same time, there might be things actually going on 398 00:22:35,560 --> 00:22:40,159 Speaker 3: with our society, with our economy that make this medication 399 00:22:40,600 --> 00:22:44,560 Speaker 3: more desirable or more useful to people. This idea that 400 00:22:44,600 --> 00:22:47,960 Speaker 3: we're doing more repetitive tasks, that the amount of content 401 00:22:48,080 --> 00:22:51,159 Speaker 3: available to us is basically endless, and so if we 402 00:22:51,240 --> 00:22:54,080 Speaker 3: have a drug that makes it more even more enjoyable 403 00:22:54,440 --> 00:22:56,879 Speaker 3: to sift through all of it. It's sort of like 404 00:22:57,000 --> 00:22:59,240 Speaker 3: two self reinforcing things here. 405 00:23:00,119 --> 00:23:01,800 Speaker 4: Yeah, absolutely, And I mean I think I want to 406 00:23:01,880 --> 00:23:04,000 Speaker 4: duck out of coming down on the side of chicken 407 00:23:04,160 --> 00:23:07,439 Speaker 4: or egg here. Right, these things are co constitutive. But 408 00:23:07,920 --> 00:23:09,720 Speaker 4: the reason that I wrote the piece was that I 409 00:23:09,720 --> 00:23:12,080 Speaker 4: think that there has been a prevalence of a certain 410 00:23:12,200 --> 00:23:15,600 Speaker 4: kind of narrative about the relation between the so called 411 00:23:15,640 --> 00:23:20,359 Speaker 4: attention crisis, the Internet and aderall. And I think in 412 00:23:20,440 --> 00:23:22,800 Speaker 4: most of the commentary that I've read, even commentary that 413 00:23:22,840 --> 00:23:26,639 Speaker 4: has been very critical of the proliferation of telehealth startups 414 00:23:26,680 --> 00:23:29,479 Speaker 4: such as Cerebral or Done, and I'm sure we'll talk 415 00:23:29,520 --> 00:23:33,480 Speaker 4: about those in a little bit. Even in these critiques 416 00:23:34,080 --> 00:23:37,800 Speaker 4: of the overreaches of telepsychiatry and the sudden boom, the 417 00:23:37,920 --> 00:23:42,840 Speaker 4: latest boom in prescription for ADHD and add stimulant medication, 418 00:23:43,520 --> 00:23:48,080 Speaker 4: there's this idea that we are medicating an attention crisis 419 00:23:48,119 --> 00:23:51,000 Speaker 4: that is in fact caused by the prevalence of smartphones 420 00:23:51,000 --> 00:23:53,600 Speaker 4: in the Internet. So then the causal chain there would 421 00:23:53,600 --> 00:23:57,000 Speaker 4: be first you have the Internet, then you have the 422 00:23:57,040 --> 00:24:02,840 Speaker 4: attention crisis, and then we're medicating that attention crisis through adderall. 423 00:24:02,880 --> 00:24:06,120 Speaker 4: And I think that that's only one half of the story. 424 00:24:06,520 --> 00:24:09,159 Speaker 4: One of the arguments that I make in the piece 425 00:24:09,359 --> 00:24:12,240 Speaker 4: is that, in fact, if you look at the emergence 426 00:24:12,400 --> 00:24:15,280 Speaker 4: of let's say, millennial Internet culture, which is to say, 427 00:24:15,320 --> 00:24:18,960 Speaker 4: sort of smartphone CUSP internet culture, first of all, the 428 00:24:18,960 --> 00:24:23,160 Speaker 4: technical architecture of the Internet is overwhelmingly created by people 429 00:24:23,200 --> 00:24:26,600 Speaker 4: who are on stimulants. If you think about the extraordinary 430 00:24:26,720 --> 00:24:31,920 Speaker 4: prevalence of ADHD medication among coders, you could hardly imagine 431 00:24:31,960 --> 00:24:36,080 Speaker 4: a job that lends itself better to the sort of 432 00:24:36,400 --> 00:24:39,720 Speaker 4: jacking up of reward systems that amfetines produced than the 433 00:24:39,760 --> 00:24:43,359 Speaker 4: extremely boring task of coding. Right. So there's that. And 434 00:24:43,400 --> 00:24:46,159 Speaker 4: then also if you kind of think about that moment 435 00:24:46,240 --> 00:24:49,200 Speaker 4: from let's say two thousand and five to twenty fifteen, 436 00:24:49,760 --> 00:24:53,080 Speaker 4: where you had the proliferation of things like alt lit, 437 00:24:53,280 --> 00:24:58,600 Speaker 4: tau l in, Ben Lerner, Jonathan Saffaran Foyer, Vice Pitchfork, right, 438 00:24:58,640 --> 00:25:01,600 Speaker 4: if you think about that sort of milange that was 439 00:25:01,920 --> 00:25:05,480 Speaker 4: that moment in the culture, I think that one of 440 00:25:05,520 --> 00:25:10,960 Speaker 4: the defining features of that zeitgeist was the prevalence of 441 00:25:11,000 --> 00:25:13,640 Speaker 4: adderall and the prevalence of millennials who had either been 442 00:25:13,640 --> 00:25:17,080 Speaker 4: put on adderall as children, overwhelming the upper middle class 443 00:25:17,160 --> 00:25:19,720 Speaker 4: ensured children who then go on to sort of set 444 00:25:19,800 --> 00:25:23,240 Speaker 4: the BPM of the culture in the zeitgeist, right or 445 00:25:23,400 --> 00:25:26,640 Speaker 4: the dissemination of adderall through elite college networks. 446 00:25:27,560 --> 00:25:30,280 Speaker 2: I want to get to the rise of telehealth and 447 00:25:30,320 --> 00:25:32,639 Speaker 2: the pandemic and how that sort of opened up the 448 00:25:32,640 --> 00:25:34,440 Speaker 2: door to many more people. But before we even get 449 00:25:34,440 --> 00:25:37,640 Speaker 2: to the sort of broader question, is it a phenomenon 450 00:25:37,720 --> 00:25:40,119 Speaker 2: when you looking at history, and it certainly sounds like 451 00:25:40,119 --> 00:25:44,280 Speaker 2: it where whether it's the government or regulators or the 452 00:25:44,320 --> 00:25:47,360 Speaker 2: medical profession, it sounds like these things go in waves, 453 00:25:47,440 --> 00:25:51,239 Speaker 2: and it's like there's a drug gets prescribed popularly. Then 454 00:25:51,280 --> 00:25:53,840 Speaker 2: there's a backlash and everyone gets concerned. Maybe we're part 455 00:25:53,840 --> 00:25:56,440 Speaker 2: of the backlash right now to adderall. Then everyone gets concerned. 456 00:25:56,600 --> 00:25:59,560 Speaker 2: Then it sort of attenuates for a while, and then 457 00:25:59,680 --> 00:26:01,919 Speaker 2: suddenly there's a new reason and then it picks back up. 458 00:26:02,200 --> 00:26:06,160 Speaker 2: Is that a general phenomenon in psychology? 459 00:26:07,359 --> 00:26:10,520 Speaker 4: Yeah, Well, you know, I think that I'm prone to 460 00:26:10,560 --> 00:26:13,760 Speaker 4: describe things as a dialectic in that sense, I would 461 00:26:13,800 --> 00:26:16,280 Speaker 4: say yes, But you can see this type of pattern 462 00:26:16,359 --> 00:26:20,439 Speaker 4: and a variety of psychiatric medications. For instance, if you 463 00:26:20,520 --> 00:26:27,639 Speaker 4: think about the emergence of antidepressants SSRIs, SNRIs like prozac, likexepro, 464 00:26:27,920 --> 00:26:30,960 Speaker 4: well beutrid and so on and so forth in the nineties, 465 00:26:31,040 --> 00:26:35,720 Speaker 4: there is a huge amount of optimism about the serotonin hypothesis, 466 00:26:35,760 --> 00:26:39,200 Speaker 4: that is that serious mood disorders like depression are caused 467 00:26:39,240 --> 00:26:42,199 Speaker 4: by a deficiency of serotonin in the brain. And this 468 00:26:42,400 --> 00:26:48,119 Speaker 4: is coterminous with very serious marketing campaigns by pharmaceutical companies 469 00:26:48,480 --> 00:26:52,960 Speaker 4: that include things like funding patients advocacy groups to sort 470 00:26:52,960 --> 00:26:56,840 Speaker 4: of demand recognition and access to these drugs. And then 471 00:26:56,880 --> 00:27:00,520 Speaker 4: you have this sort of decline in optimism around these 472 00:27:00,600 --> 00:27:03,960 Speaker 4: drugs that I would say dates roughly to twenty ten, 473 00:27:04,359 --> 00:27:08,240 Speaker 4: and the sort of fall in optimism because in fact, 474 00:27:08,600 --> 00:27:11,920 Speaker 4: most SSRIs and sent arized do not perform very much 475 00:27:11,960 --> 00:27:15,439 Speaker 4: better than placebos when looked at in aggregate, that is, 476 00:27:15,520 --> 00:27:17,800 Speaker 4: through meta analyzes, and so I do think that there 477 00:27:17,880 --> 00:27:20,720 Speaker 4: is a kind of push and pull here that is 478 00:27:20,800 --> 00:27:25,840 Speaker 4: maybe not so dissimilar to this general dynamic in psychiatric 479 00:27:25,880 --> 00:27:30,240 Speaker 4: medications more broadly. But what's interesting about amphetamines in particular 480 00:27:30,760 --> 00:27:33,480 Speaker 4: is that sort of the first wave of amphetamine use 481 00:27:34,040 --> 00:27:38,120 Speaker 4: really gets going during World War Two, when both Allied 482 00:27:38,200 --> 00:27:42,760 Speaker 4: and Axis powers are using amphetamines or in the case 483 00:27:42,800 --> 00:27:46,960 Speaker 4: of the Germans, just meth straight up to fuel wartime 484 00:27:47,359 --> 00:27:50,399 Speaker 4: activities and to quote unquote boost morale. But I mean, 485 00:27:50,480 --> 00:27:54,120 Speaker 4: there's a historian named Norman Ohler has laid out very capably. 486 00:27:54,160 --> 00:27:57,399 Speaker 4: I think the argument that, like for instance, Blitzkraig, cannot 487 00:27:57,440 --> 00:28:01,520 Speaker 4: be understood apart from the widespread use of by German troops. 488 00:28:01,640 --> 00:28:04,800 Speaker 4: So you have the sort of large, large spike in 489 00:28:04,920 --> 00:28:08,800 Speaker 4: population levels of usage around World War Two, that sort 490 00:28:08,800 --> 00:28:11,320 Speaker 4: of rises and rises and rises and rises. And then 491 00:28:11,760 --> 00:28:15,719 Speaker 4: with the sort of panic around overprescription among children in 492 00:28:15,760 --> 00:28:19,760 Speaker 4: the early nineteen seventies, I think that that backlash against 493 00:28:19,800 --> 00:28:23,120 Speaker 4: the sort of psychiatric medication being used on children has 494 00:28:23,160 --> 00:28:27,120 Speaker 4: to be understood in tandem with, for instance, youth counterculture, 495 00:28:27,560 --> 00:28:31,480 Speaker 4: with youth suspicion of the way that older generations were, 496 00:28:31,560 --> 00:28:34,639 Speaker 4: you know, doing things like suppressing student organizing. Right, the 497 00:28:35,080 --> 00:28:38,240 Speaker 4: youth culture comes to be this sort of anti establishment 498 00:28:38,760 --> 00:28:43,320 Speaker 4: suspicion of a variety of different systems, including electoral systems, 499 00:28:43,320 --> 00:28:47,160 Speaker 4: but also specifically the psychiatric system as an agent of control. Right, 500 00:28:47,200 --> 00:28:50,680 Speaker 4: So if you think about, for instance, Michelle Fucou, Thomas Zazz, 501 00:28:51,080 --> 00:28:53,680 Speaker 4: the wide spectrum of thinkers in the nineteen seventies who 502 00:28:53,720 --> 00:28:56,600 Speaker 4: were explicitly making the case that psychiatry was an agent 503 00:28:56,640 --> 00:29:02,480 Speaker 4: of social control. The backlash against emphetamines, particularly emphatamines, being 504 00:29:02,600 --> 00:29:06,680 Speaker 4: used to treat child behavioral disorders becomes a bit more legible, 505 00:29:07,120 --> 00:29:09,520 Speaker 4: and so then, of course, you know, in the nineteen eighties, 506 00:29:09,680 --> 00:29:13,000 Speaker 4: with the crackdown on emphetamines, this is one of the 507 00:29:13,000 --> 00:29:16,800 Speaker 4: conditions for the rise of cocaine usage, for instance. But 508 00:29:16,840 --> 00:29:19,000 Speaker 4: I think that there is this kind of push and pull, 509 00:29:19,360 --> 00:29:22,800 Speaker 4: a sort of dialectic, if you will, between the cultural 510 00:29:22,880 --> 00:29:25,800 Speaker 4: meanings of em fetamine, and we're now at a moment 511 00:29:25,880 --> 00:29:30,360 Speaker 4: where I think there's real tension between a narrative that says, oh, well, 512 00:29:30,480 --> 00:29:33,280 Speaker 4: when you look at the increase in prescriptions that have 513 00:29:33,400 --> 00:29:36,880 Speaker 4: been enabled by, for instance, the rise of telepsychiatry, most 514 00:29:36,880 --> 00:29:39,760 Speaker 4: of those prescriptions are going to women in their twenties 515 00:29:39,760 --> 00:29:42,840 Speaker 4: and thirties who may have been, you know, left out 516 00:29:42,920 --> 00:29:46,920 Speaker 4: of a sort of sexist division of prescribing, whereby their 517 00:29:46,960 --> 00:29:51,560 Speaker 4: ADHD was not recognized for gendered reasons. So on the 518 00:29:51,600 --> 00:29:54,800 Speaker 4: one hand, that would be good presumably right. And then 519 00:29:54,960 --> 00:29:57,920 Speaker 4: you know another line of critique that says that the 520 00:29:57,960 --> 00:30:03,360 Speaker 4: shocking and enormous rise in stimulant prescription, especially during the pandemic, 521 00:30:03,520 --> 00:30:06,520 Speaker 4: is maybe more profit driven and not so salutary. And 522 00:30:06,600 --> 00:30:09,080 Speaker 4: I think like that's the space in which this conversation 523 00:30:09,160 --> 00:30:23,920 Speaker 4: is unfolding today. 524 00:30:25,680 --> 00:30:31,960 Speaker 3: What actually drives the availability of adderall currently? Is it regulation? 525 00:30:32,240 --> 00:30:35,240 Speaker 3: And one thing I didn't realize before I started asking 526 00:30:35,280 --> 00:30:38,560 Speaker 3: around about this, but Adderall isn't licensed in the UK, 527 00:30:38,960 --> 00:30:41,080 Speaker 3: so I don't think you can get a prescription for 528 00:30:41,080 --> 00:30:44,360 Speaker 3: adderall over there. Is it the rise of prescriptions, the 529 00:30:44,440 --> 00:30:47,920 Speaker 3: increased use of telehealth which makes it maybe easier to 530 00:30:48,080 --> 00:30:51,800 Speaker 3: access this drug, or is it the companies themselves? I 531 00:30:51,840 --> 00:30:55,160 Speaker 3: mean this has been a talking point with the opioid epidemic, 532 00:30:55,240 --> 00:30:58,040 Speaker 3: this idea that there is a built in incentive for 533 00:30:58,200 --> 00:31:02,720 Speaker 3: a pharma company to want to demand for its own supply. 534 00:31:02,920 --> 00:31:06,360 Speaker 3: So what exactly is driving the availability here? 535 00:31:07,120 --> 00:31:09,240 Speaker 4: Yeah? Okay, So I think this is where maybe we 536 00:31:09,280 --> 00:31:14,320 Speaker 4: talk about what is specific about pandemic telepsychiatry to the 537 00:31:14,360 --> 00:31:17,440 Speaker 4: recent adderall boom. I think the first thing to be noted, 538 00:31:17,520 --> 00:31:20,920 Speaker 4: as you mentioned, is that this is a specifically US phenomenon. 539 00:31:21,000 --> 00:31:24,080 Speaker 4: And I think that, like for all of the activism, 540 00:31:24,080 --> 00:31:25,959 Speaker 4: and I'm sure, like you know, I'm going to get 541 00:31:26,000 --> 00:31:28,480 Speaker 4: a lot of angry emails after this podcast you always 542 00:31:28,520 --> 00:31:33,480 Speaker 4: get about I mean, honestly, don't email me, but you 543 00:31:33,520 --> 00:31:35,680 Speaker 4: know what I mean. I think that for all that 544 00:31:35,680 --> 00:31:38,960 Speaker 4: people want to really double down on the validity of 545 00:31:39,000 --> 00:31:43,240 Speaker 4: the ADD or ADHD diagnosis, there is, you know, significant 546 00:31:43,280 --> 00:31:46,479 Speaker 4: evidence that this is a culturally bound phenomenon just by 547 00:31:46,600 --> 00:31:50,400 Speaker 4: virtue of the fact that it is essentially a US 548 00:31:50,480 --> 00:31:52,840 Speaker 4: bounded phenomenon. I think that people should take that pretty 549 00:31:52,840 --> 00:31:56,160 Speaker 4: seriously when we think about what is driving the current 550 00:31:56,240 --> 00:31:59,680 Speaker 4: adderall shortage, which was announced by the FDA in October 551 00:31:59,680 --> 00:32:03,480 Speaker 4: of two. In twenty two, because of the classification of 552 00:32:03,600 --> 00:32:06,560 Speaker 4: m fatamines as a schedule to substance in the nineteen 553 00:32:06,600 --> 00:32:10,600 Speaker 4: seventy one order from Congress to the DEA. This means 554 00:32:10,600 --> 00:32:14,480 Speaker 4: that there are quotas that are established for how many 555 00:32:14,520 --> 00:32:17,959 Speaker 4: emphatamine salts can be produced and how those are distributed. Now, 556 00:32:18,000 --> 00:32:20,880 Speaker 4: there's been a lot of back and forth between pharmaceutical 557 00:32:20,920 --> 00:32:23,960 Speaker 4: companies and the DA sort of pointing fingers, and the 558 00:32:24,000 --> 00:32:26,800 Speaker 4: DEA says that in fact, what's going on is that 559 00:32:27,120 --> 00:32:32,600 Speaker 4: pharmaceutical manufacturers are not actually hitting their production quotas. Pharmaceutical 560 00:32:32,640 --> 00:32:35,760 Speaker 4: companies are striking back and saying no, in fact, the 561 00:32:35,800 --> 00:32:39,600 Speaker 4: production quotas on the amphetamine salts themselves are too low. 562 00:32:39,800 --> 00:32:42,240 Speaker 4: I don't actually know which one is true. It seems 563 00:32:42,280 --> 00:32:44,720 Speaker 4: pretty hard to figure out which one is true. But 564 00:32:44,800 --> 00:32:49,080 Speaker 4: when we look at the enormous recent spike, even between 565 00:32:49,320 --> 00:32:53,800 Speaker 4: twenty nineteen and twenty twenty two. In twenty nineteen, for instance, 566 00:32:53,880 --> 00:32:57,560 Speaker 4: there were sixty six point six million prescriptions for all 567 00:32:57,840 --> 00:33:02,480 Speaker 4: ADHD medications that includes things like vibance, concerta riddle and 568 00:33:02,520 --> 00:33:06,000 Speaker 4: so on, in forty five million for adderall alone, And 569 00:33:06,120 --> 00:33:09,000 Speaker 4: in the first two years of the pandemic there was 570 00:33:09,040 --> 00:33:12,920 Speaker 4: six million new prescriptions. So one of the narratives that 571 00:33:13,040 --> 00:33:18,080 Speaker 4: you'll hear a lot about this extraordinary rise in stimulant 572 00:33:18,160 --> 00:33:20,960 Speaker 4: prescriptions is that this is owing to the proliferation of 573 00:33:21,000 --> 00:33:25,600 Speaker 4: telepsychiatry companies like Cerebral Done and so on. And I 574 00:33:25,600 --> 00:33:29,160 Speaker 4: think this only gets a part of the story. During COVID, 575 00:33:29,360 --> 00:33:33,640 Speaker 4: the rule that mandated that Schedule two substances could not 576 00:33:33,800 --> 00:33:39,520 Speaker 4: be prescribed over telepsychiatry was lifted, which meant, especially that 577 00:33:39,560 --> 00:33:44,080 Speaker 4: people who had never had an ADHD medication prescription before 578 00:33:44,320 --> 00:33:47,800 Speaker 4: could suddenly get one. There's been a lot of fighting 579 00:33:47,880 --> 00:33:50,520 Speaker 4: over whether or not that rule will be extended, but 580 00:33:50,560 --> 00:33:53,760 Speaker 4: that's certainly a huge part of the proliferation of these 581 00:33:53,760 --> 00:33:57,640 Speaker 4: telepsychiatry prescription rates. But what's interesting is that a recent 582 00:33:57,680 --> 00:34:02,400 Speaker 4: study using CDC data know that the rise through tele 583 00:34:02,440 --> 00:34:08,520 Speaker 4: psychiatry of these prescriptions are specific to VC backed startups. 584 00:34:08,560 --> 00:34:12,080 Speaker 4: That is, if you were getting telepsychiatry through a sort 585 00:34:12,120 --> 00:34:16,080 Speaker 4: of established provider like let's say Kaiser or something who 586 00:34:16,160 --> 00:34:18,719 Speaker 4: had been doing tele psychiatry before, there was not a 587 00:34:18,800 --> 00:34:22,680 Speaker 4: huge increase in adderall prescriptions for those types of companies. 588 00:34:22,880 --> 00:34:25,640 Speaker 4: It was specifically the emergence of these new types of 589 00:34:25,640 --> 00:34:30,400 Speaker 4: companies like Cerebral and Done that were pushing this enormous 590 00:34:30,400 --> 00:34:32,880 Speaker 4: increase in diagnosis. And I think that part of this 591 00:34:33,000 --> 00:34:35,279 Speaker 4: is just a pretty open and shutcase of like a 592 00:34:35,360 --> 00:34:40,280 Speaker 4: company basing its profit model on slinging addictive medications into 593 00:34:40,280 --> 00:34:42,920 Speaker 4: this loophole that was created by the pandemic. The Wall 594 00:34:42,920 --> 00:34:47,000 Speaker 4: Street Journal has done a pretty magisterial and heroic reporting 595 00:34:47,080 --> 00:34:49,600 Speaker 4: job I think of documenting that. But one of the 596 00:34:49,640 --> 00:34:52,160 Speaker 4: interesting thing that comes out of that type of reporting 597 00:34:52,680 --> 00:34:56,239 Speaker 4: is that it's very difficult to get national data about 598 00:34:56,320 --> 00:35:00,799 Speaker 4: levels of prescribing because there is no rule MANDATEA that 599 00:35:01,080 --> 00:35:05,040 Speaker 4: the number of prescriptions for these stimulants be made publicly 600 00:35:05,080 --> 00:35:07,520 Speaker 4: available in any way. The CDC has to collect this 601 00:35:07,600 --> 00:35:10,959 Speaker 4: data by doing reviews of private insurance records, but those 602 00:35:11,040 --> 00:35:13,400 Speaker 4: tend to lag by about a year to two years. 603 00:35:13,400 --> 00:35:16,719 Speaker 4: And so when we all started seeing these advertisements for 604 00:35:16,800 --> 00:35:20,239 Speaker 4: cerebral which were all over TikTok, all over Instagram, that 605 00:35:20,280 --> 00:35:23,239 Speaker 4: were basically like do you want some adderall you can 606 00:35:23,280 --> 00:35:26,840 Speaker 4: basically have some, it was very hard for reporters to 607 00:35:26,880 --> 00:35:31,120 Speaker 4: sort of track the increase that was actually represented by 608 00:35:31,160 --> 00:35:34,279 Speaker 4: those prescribing numbers because they simply aren't federally available. I mean, 609 00:35:34,320 --> 00:35:37,439 Speaker 4: I think among the many arguments for a national health 610 00:35:37,480 --> 00:35:39,640 Speaker 4: insurance or Medicare for All as it's called in the 611 00:35:39,760 --> 00:35:43,279 Speaker 4: United States, is that it's very difficult to track the 612 00:35:43,440 --> 00:35:47,560 Speaker 4: number of controlled substance prescriptions in a way that sort 613 00:35:47,560 --> 00:35:50,400 Speaker 4: of stays ocurrant. You know, this is also relevant I 614 00:35:50,440 --> 00:35:53,239 Speaker 4: think too, for instance, the opiate crisis. But yes, I 615 00:35:53,280 --> 00:35:56,680 Speaker 4: think that when you look at this enormous increase in 616 00:35:56,840 --> 00:36:01,680 Speaker 4: telepsychiatry prescription, there's both this sort of que bono line 617 00:36:01,719 --> 00:36:03,520 Speaker 4: that you can take of, just like there was an 618 00:36:03,640 --> 00:36:06,240 Speaker 4: enormous amount of money to be made through these telepsychiatry 619 00:36:06,560 --> 00:36:11,600 Speaker 4: loopholes that allowed slinging these addictive substances into a pandemic. 620 00:36:12,000 --> 00:36:15,480 Speaker 4: And then simultaneously, I think there is the reality that 621 00:36:15,640 --> 00:36:19,719 Speaker 4: it was enormously difficult to pay attention to anything during 622 00:36:19,760 --> 00:36:22,520 Speaker 4: the pandemic, which contributed I think to many people feeling 623 00:36:22,600 --> 00:36:25,040 Speaker 4: that because it was difficult for them to pay attention 624 00:36:25,120 --> 00:36:27,640 Speaker 4: in zooms for ten hours or you know, or however 625 00:36:27,680 --> 00:36:29,640 Speaker 4: long it was, that they must have some sort of 626 00:36:29,640 --> 00:36:31,439 Speaker 4: attention deficit diagnosis. 627 00:36:31,719 --> 00:36:35,920 Speaker 2: I find that really fascinating this idea, especially that point 628 00:36:35,960 --> 00:36:39,960 Speaker 2: about the gap and the increase in prescriptions from the 629 00:36:40,000 --> 00:36:43,240 Speaker 2: sort of vcback startups which we know need growth, growth, growth, 630 00:36:43,600 --> 00:36:46,879 Speaker 2: versus the sort of legacy healthcare providers that had been 631 00:36:46,920 --> 00:36:51,000 Speaker 2: doing telemedicine for some time that didn't pick up. I 632 00:36:51,000 --> 00:36:53,560 Speaker 2: guess I should have just like done a test, But like, 633 00:36:53,600 --> 00:36:55,239 Speaker 2: what do you have to demonstrate to get at all? 634 00:36:55,280 --> 00:36:58,640 Speaker 2: Presumably you can't just click a button. 635 00:36:58,320 --> 00:36:59,520 Speaker 3: But how simple you can? 636 00:36:59,680 --> 00:37:00,400 Speaker 4: Is it? Like? 637 00:37:00,440 --> 00:37:02,960 Speaker 2: What is there some sort of basic test? And like 638 00:37:03,000 --> 00:37:06,160 Speaker 2: do different doctors, like do the ones who worked through 639 00:37:06,200 --> 00:37:13,360 Speaker 2: the legacy providers have a more perhaps stringent test or expectations, 640 00:37:13,440 --> 00:37:16,080 Speaker 2: like what do the various types of medical professionals want 641 00:37:16,080 --> 00:37:17,800 Speaker 2: to see before they'll write data prescription. 642 00:37:18,400 --> 00:37:20,960 Speaker 4: I mean, I think the most succinct answer to this 643 00:37:21,080 --> 00:37:25,840 Speaker 4: question is that it has been and remains essentially vibes based, 644 00:37:26,040 --> 00:37:30,160 Speaker 4: and the quality of that vibees based assessment basically depends 645 00:37:30,280 --> 00:37:33,640 Speaker 4: on the quality of the medical care that you're receiving. 646 00:37:34,120 --> 00:37:36,920 Speaker 4: I mean, I remember that when I was prescribed adderall 647 00:37:37,000 --> 00:37:39,239 Speaker 4: as an eight year old, I went to like a 648 00:37:39,320 --> 00:37:43,320 Speaker 4: child psychiatrist who played a board game with me called Stop, 649 00:37:43,400 --> 00:37:46,640 Speaker 4: Relax and Think loosely based off of shoots and ladders, 650 00:37:46,880 --> 00:37:48,319 Speaker 4: and at the end of that, I walked out with 651 00:37:48,320 --> 00:37:51,080 Speaker 4: an adderall prescription, Right, And so, like, the thing is, 652 00:37:51,320 --> 00:37:54,720 Speaker 4: there's not any sort of blood test or genetic test 653 00:37:55,239 --> 00:37:58,880 Speaker 4: or brain scan that you could take that would stitch 654 00:37:59,239 --> 00:38:04,280 Speaker 4: some sort of by physiological substrate to this disease entity, 655 00:38:04,280 --> 00:38:07,960 Speaker 4: and to say there's no one to one correspondence between 656 00:38:08,160 --> 00:38:10,480 Speaker 4: the disease entity and some sort of test that you 657 00:38:10,520 --> 00:38:13,359 Speaker 4: could take, because it's not actually clear out neurological level 658 00:38:13,800 --> 00:38:17,839 Speaker 4: what this disease entity quote unquote is and so in 659 00:38:17,840 --> 00:38:22,399 Speaker 4: that sense, assessment is bound to be essentially vibespace. Now, 660 00:38:22,680 --> 00:38:26,000 Speaker 4: you know, if you have a clinician who is behaving responsibly, 661 00:38:26,480 --> 00:38:29,480 Speaker 4: they will do a variety of tests and sort of 662 00:38:29,560 --> 00:38:32,480 Speaker 4: ask either the child or the parent, or in the 663 00:38:32,480 --> 00:38:36,640 Speaker 4: case of adult ADHD diagnosis, the patient themselves about their 664 00:38:36,640 --> 00:38:41,080 Speaker 4: functioning across a variety of domains, including focus on work organization, 665 00:38:41,719 --> 00:38:43,920 Speaker 4: ability to sit still for long periods of time, and 666 00:38:43,920 --> 00:38:46,560 Speaker 4: so on and so forth. But in reality, there is 667 00:38:46,680 --> 00:38:53,480 Speaker 4: not really a robust test that differentiates people who do 668 00:38:53,600 --> 00:38:56,680 Speaker 4: have add from people who don't, even in the best 669 00:38:56,840 --> 00:39:00,840 Speaker 4: of cases, even in the case of very high quality 670 00:39:00,880 --> 00:39:04,440 Speaker 4: in person pediatric or adult psychiatric care. Now, when it 671 00:39:04,480 --> 00:39:08,360 Speaker 4: comes to something like telepsychiatry startups like done in Cerebral, 672 00:39:08,480 --> 00:39:10,880 Speaker 4: I think that there's been a lot of reporting and 673 00:39:10,960 --> 00:39:15,320 Speaker 4: documentation now on the way that providers who were essentially 674 00:39:15,360 --> 00:39:19,799 Speaker 4: working in this sort of gig economy Uber for psychiatric 675 00:39:19,800 --> 00:39:24,880 Speaker 4: professionals type of platform were punished if they refused to 676 00:39:24,920 --> 00:39:29,160 Speaker 4: prescribe stimulants at Cerebral for a while, if you refuse 677 00:39:29,280 --> 00:39:31,920 Speaker 4: to prescribe a stimulant, you had to write up a 678 00:39:32,040 --> 00:39:35,520 Speaker 4: justification for why you were not doing that, you would 679 00:39:35,520 --> 00:39:39,680 Speaker 4: think that responsible medical practice would be the opposite. Cerebral 680 00:39:39,719 --> 00:39:43,480 Speaker 4: has since after this series of investigations that prompted a 681 00:39:43,560 --> 00:39:48,840 Speaker 4: DJ investigation, stopped prescribing schedule to substances through their platform. 682 00:39:49,200 --> 00:39:51,359 Speaker 4: But I think that regardless of whether or not they're 683 00:39:51,360 --> 00:39:54,359 Speaker 4: still slinging like adderall or concerto on there, I think 684 00:39:54,360 --> 00:39:57,880 Speaker 4: that it bears on, for instance, what kinds of assessments 685 00:39:57,920 --> 00:40:01,440 Speaker 4: are being used to prescribe for it antidepressants, which are 686 00:40:01,480 --> 00:40:05,080 Speaker 4: also serious, psychoactive medifications that can be very very difficult 687 00:40:05,480 --> 00:40:08,600 Speaker 4: to wean off of. But in short, answers to your question, no, 688 00:40:08,840 --> 00:40:15,239 Speaker 4: there's no specific diagnostic test that guarantees the appropriateness of 689 00:40:15,440 --> 00:40:17,240 Speaker 4: amphetamines for any given patient. 690 00:40:17,960 --> 00:40:20,040 Speaker 3: This is a very wide ranging question. But what are 691 00:40:20,080 --> 00:40:25,040 Speaker 3: the implications for society of this increased adderall use? And 692 00:40:25,160 --> 00:40:30,120 Speaker 3: obviously there's a physical impact of having a higher proportion 693 00:40:30,280 --> 00:40:35,680 Speaker 3: of the population dependent in varying degrees on a particular substance. 694 00:40:36,000 --> 00:40:39,040 Speaker 3: But also I kind of joked in the intro about 695 00:40:39,239 --> 00:40:43,000 Speaker 3: unfairness and competitive edges here and then Joe said that 696 00:40:43,040 --> 00:40:45,520 Speaker 3: it's not the Olympics, but of course life is competitive, 697 00:40:45,560 --> 00:40:49,040 Speaker 3: and it is in some degree a competition, and you 698 00:40:49,080 --> 00:40:52,520 Speaker 3: could make a serious argument that, like, some people have 699 00:40:52,719 --> 00:40:57,320 Speaker 3: access to a drug that increases their productivity and has 700 00:40:57,600 --> 00:41:02,080 Speaker 3: positive outcomes on their economic lives at the very least, 701 00:41:02,080 --> 00:41:06,040 Speaker 3: So you have people who have boosted their careers by 702 00:41:06,080 --> 00:41:08,279 Speaker 3: being on this particular drug. And maybe they got the 703 00:41:08,280 --> 00:41:11,800 Speaker 3: prescription when they were younger because their parents had money 704 00:41:11,880 --> 00:41:14,400 Speaker 3: and health insurance and were able to get it, or 705 00:41:14,480 --> 00:41:17,719 Speaker 3: maybe they had a network of friends who are on 706 00:41:17,880 --> 00:41:20,960 Speaker 3: the drug or have access to it. In another slightly 707 00:41:21,000 --> 00:41:23,640 Speaker 3: more dubious way, it does feel like there might be 708 00:41:23,680 --> 00:41:26,399 Speaker 3: some fairness questions tied to this. 709 00:41:27,360 --> 00:41:29,279 Speaker 4: Yeah, I think one of the first things to be 710 00:41:29,320 --> 00:41:32,279 Speaker 4: said about this is, like so many other things in 711 00:41:32,320 --> 00:41:36,160 Speaker 4: psychiatric treatment, there are a series of strange paradoxes that 712 00:41:36,640 --> 00:41:41,719 Speaker 4: define how amphetamine treatment have been used over the twentieth century. So, 713 00:41:41,880 --> 00:41:45,480 Speaker 4: for instance, one of the big pushes against the use 714 00:41:45,520 --> 00:41:48,440 Speaker 4: of Riddlin for children in the nineteen seventies came from 715 00:41:48,520 --> 00:41:52,839 Speaker 4: the Black Panthers, who saw that amphetamines and Riddlin were 716 00:41:52,880 --> 00:41:56,960 Speaker 4: being tested on children in residential care facilities, many of 717 00:41:57,000 --> 00:42:00,719 Speaker 4: whom were black, right, And so there was a sort 718 00:42:00,760 --> 00:42:06,719 Speaker 4: of lower class iffication of amphetamines in the nineteen seventies 719 00:42:06,840 --> 00:42:11,960 Speaker 4: because they were being tested on populations in juvenile detention centers, 720 00:42:12,200 --> 00:42:15,239 Speaker 4: residential care homes, so on and so forth. There's a 721 00:42:15,280 --> 00:42:18,960 Speaker 4: real switch in the nineties, right when suddenly attention deficit 722 00:42:19,000 --> 00:42:24,560 Speaker 4: disorders become kind of the explanation for why white, well ensured, 723 00:42:24,640 --> 00:42:26,879 Speaker 4: upper middle class children are not doing as well as 724 00:42:26,880 --> 00:42:29,080 Speaker 4: would be expected in class. And so I think I 725 00:42:29,160 --> 00:42:31,920 Speaker 4: say that to just sort of problematize some of the 726 00:42:32,000 --> 00:42:35,960 Speaker 4: narratives that like emfetamine usage, it has always been considered 727 00:42:36,000 --> 00:42:40,479 Speaker 4: an upper middle class competitive edge thing, and I think 728 00:42:40,680 --> 00:42:45,080 Speaker 4: in line with this, for instance, I don't think necessarily 729 00:42:45,160 --> 00:42:49,000 Speaker 4: that empfetamine use always gives someone a sort of performance 730 00:42:49,440 --> 00:42:52,480 Speaker 4: enhancing edge. One of the arguments that I make in 731 00:42:52,520 --> 00:42:55,440 Speaker 4: the Adderall essay that I wrote is that in fact 732 00:42:55,520 --> 00:42:59,960 Speaker 4: adderall makes you more susceptible to different types of digital 733 00:43:00,040 --> 00:43:04,960 Speaker 4: behavioral loops, these addictive digital behavioral loops like scrolling Twitter 734 00:43:05,080 --> 00:43:09,880 Speaker 4: infinitely or scrolling TikTok infinitely that sort of directly impact 735 00:43:09,960 --> 00:43:13,920 Speaker 4: one's ability to lead like a thoughtful, well informed life. 736 00:43:14,640 --> 00:43:15,160 Speaker 3: One of the. 737 00:43:15,719 --> 00:43:21,000 Speaker 4: Interesting responses to the club Med Adderall essay collection I 738 00:43:21,040 --> 00:43:22,880 Speaker 4: thought was that there was a lot of anger and 739 00:43:23,000 --> 00:43:27,040 Speaker 4: accusations that some of the arguments that the authors made 740 00:43:27,239 --> 00:43:31,960 Speaker 4: were prohibitionist in impulse, And I can see why that 741 00:43:32,000 --> 00:43:35,479 Speaker 4: would be a concern, but I think that it's misplaced, because, 742 00:43:35,520 --> 00:43:39,479 Speaker 4: in fact, if you think about the clinically documented fact 743 00:43:39,520 --> 00:43:41,880 Speaker 4: that there is really not that much of a difference 744 00:43:42,320 --> 00:43:46,120 Speaker 4: in effectivity for emphetamines between people who have been diagnosed 745 00:43:46,160 --> 00:43:49,319 Speaker 4: with attention deficit disorders and people who have not, then 746 00:43:49,360 --> 00:43:51,799 Speaker 4: in fact, the real prohibitionist impulse is to say that 747 00:43:51,880 --> 00:43:56,120 Speaker 4: because we have this real diagnostic clinical entity, which is 748 00:43:56,160 --> 00:43:58,759 Speaker 4: you know, in fact, like quite contested and not a 749 00:43:58,840 --> 00:44:02,520 Speaker 4: robust disease entity, all, because we have this robust disease entity, 750 00:44:02,800 --> 00:44:05,640 Speaker 4: we are the only ones who should have adderall. And 751 00:44:05,719 --> 00:44:08,080 Speaker 4: I think that there's this very serious conversation to be 752 00:44:08,120 --> 00:44:13,480 Speaker 4: had about equity and distribution and what prohibitionism actually means 753 00:44:14,040 --> 00:44:18,239 Speaker 4: in terms of the implications, however, for widespread amphetamine use. 754 00:44:18,800 --> 00:44:21,920 Speaker 4: I think that when we look at emerging forms and 755 00:44:22,040 --> 00:44:25,680 Speaker 4: organizations of work, which many theorists have described as sort 756 00:44:25,680 --> 00:44:29,200 Speaker 4: of just in time production flexible production, when you think 757 00:44:29,200 --> 00:44:33,239 Speaker 4: about the sort of increased stretching of the worker, the 758 00:44:33,320 --> 00:44:36,280 Speaker 4: need for different types of flexibility across time and space 759 00:44:36,360 --> 00:44:37,920 Speaker 4: and so on and so forth, and the sort of 760 00:44:38,280 --> 00:44:41,600 Speaker 4: ever increasing demands for a sort of infinitely flexible worker. 761 00:44:42,000 --> 00:44:43,759 Speaker 4: I think that it makes a lot of sense why 762 00:44:43,840 --> 00:44:47,760 Speaker 4: adderall or different types of amphetamines would be the drug 763 00:44:47,880 --> 00:44:49,239 Speaker 4: that facilitates that. 764 00:44:50,040 --> 00:44:51,200 Speaker 5: But I think that the. 765 00:44:51,200 --> 00:44:53,960 Speaker 4: Conversation that I hope to see emerged in the coming 766 00:44:54,080 --> 00:44:57,399 Speaker 4: years is one that's less focused on sort of who 767 00:44:57,480 --> 00:45:01,680 Speaker 4: legitimately has ADHD and who does, because in fact, these 768 00:45:01,680 --> 00:45:05,680 Speaker 4: and fetimins have remarkable advocacy for both groups that have 769 00:45:05,760 --> 00:45:08,520 Speaker 4: been diagnosed in groups that haven't, and more of a 770 00:45:08,560 --> 00:45:11,880 Speaker 4: turn towards thinking about what it is that adderall does 771 00:45:11,960 --> 00:45:14,879 Speaker 4: in terms of setting a sort of pace of freneticism 772 00:45:15,400 --> 00:45:20,880 Speaker 4: and susceptibility to different forms of behavioral addiction, particularly Internet 773 00:45:20,880 --> 00:45:24,000 Speaker 4: based behavioral addiction. And I guess my closing point here 774 00:45:24,000 --> 00:45:27,080 Speaker 4: would be that adderall cannot fix the sort of internetified 775 00:45:27,160 --> 00:45:31,240 Speaker 4: attention crisis because adderall hooks us deeper than ever into 776 00:45:31,440 --> 00:45:34,480 Speaker 4: the sort of structures of addiction that are the sand 777 00:45:34,520 --> 00:45:38,160 Speaker 4: Quanon of the Internet as a sort of giant casino 778 00:45:38,200 --> 00:45:38,920 Speaker 4: that we all live in. 779 00:45:39,480 --> 00:45:42,880 Speaker 2: Danielle, this was fascinating. We can probably talk for hours 780 00:45:43,040 --> 00:45:45,320 Speaker 2: on this subject. I just want to say I'm addicted 781 00:45:45,400 --> 00:45:49,399 Speaker 2: to Twitter and Instagram totally naturally, totally clean. But thank 782 00:45:49,480 --> 00:45:51,799 Speaker 2: you so much for coming on odd Lauds. There's a 783 00:45:51,800 --> 00:45:54,400 Speaker 2: great conversation and glad we finally got a chance. 784 00:45:54,239 --> 00:45:55,640 Speaker 4: To talk to Thank you so much. 785 00:45:55,680 --> 00:46:10,080 Speaker 5: This was really fun, Tracy. 786 00:46:10,239 --> 00:46:13,239 Speaker 2: I really enjoyed that conversation, and there were a number 787 00:46:13,239 --> 00:46:14,920 Speaker 2: of things that really are going to stick with me. 788 00:46:15,239 --> 00:46:17,839 Speaker 2: But you know, one thing that sort of I had 789 00:46:17,960 --> 00:46:21,320 Speaker 2: never really thought about before is the idea that sure 790 00:46:21,640 --> 00:46:24,200 Speaker 2: being on one of these drugs can sort of change 791 00:46:24,239 --> 00:46:27,359 Speaker 2: the way you consume information or perform tasks online, whether 792 00:46:27,400 --> 00:46:31,040 Speaker 2: productive or unproductive, but also the idea that the entire 793 00:46:31,120 --> 00:46:34,080 Speaker 2: online world was also built by the people on these drugs. 794 00:46:34,280 --> 00:46:37,319 Speaker 3: Yeah, it's sort of intertwined. Yeah, right. The other thing 795 00:46:37,320 --> 00:46:40,120 Speaker 3: that I thought was really interesting was Danielle's point about 796 00:46:40,120 --> 00:46:42,759 Speaker 3: the knowledge economy. And part of this is because I've 797 00:46:42,760 --> 00:46:46,000 Speaker 3: been reading Oh I'm going to have to Censor myself 798 00:46:46,160 --> 00:46:50,360 Speaker 3: BS Jobs by David Graber, and it's sort of like 799 00:46:50,400 --> 00:46:54,239 Speaker 3: a dystopian Studs tircle in the sense that it just 800 00:46:54,360 --> 00:46:58,200 Speaker 3: details how much dissatisfaction people seem to have with a 801 00:46:58,239 --> 00:47:01,120 Speaker 3: lot of modern day jobs where you feel like you're 802 00:47:01,160 --> 00:47:03,920 Speaker 3: not really doing anything. There's a lot of bureaucracy involved, 803 00:47:03,960 --> 00:47:07,360 Speaker 3: and yet you have to pay attention, per Danielle's points, 804 00:47:07,400 --> 00:47:09,440 Speaker 3: So I think there's an aspect of that in there. 805 00:47:09,760 --> 00:47:14,280 Speaker 3: The other thing that was very I guess attention grabbing 806 00:47:14,760 --> 00:47:18,400 Speaker 3: was the idea of no pun intended was the idea 807 00:47:18,480 --> 00:47:22,440 Speaker 3: of some of the venture capital backed health services writing 808 00:47:22,480 --> 00:47:25,799 Speaker 3: more prescriptions than perhaps some of the more traditional health 809 00:47:25,840 --> 00:47:26,640 Speaker 3: care providers. 810 00:47:27,000 --> 00:47:29,319 Speaker 2: That was totally eye opening for me, and I was, 811 00:47:29,520 --> 00:47:33,480 Speaker 2: you know, I'm aware of the proliferation of these telehealth companies. 812 00:47:33,920 --> 00:47:36,839 Speaker 2: As a mail in my mid forties, I constantly get 813 00:47:36,880 --> 00:47:39,040 Speaker 2: ads for you know, various pills that I can just 814 00:47:39,080 --> 00:47:41,200 Speaker 2: go on for like hair loss and things like that, 815 00:47:41,320 --> 00:47:44,360 Speaker 2: and so I see them targeted to me all the time. 816 00:47:44,719 --> 00:47:48,759 Speaker 2: But I hadn't realized the degree to which that specific 817 00:47:48,840 --> 00:47:54,160 Speaker 2: combination that Danielle described, which was the relaxation of prescription 818 00:47:54,400 --> 00:47:58,600 Speaker 2: drug obligations due to the pandemic and then the simultaneous 819 00:47:58,680 --> 00:48:03,320 Speaker 2: explosion of these news services, which it sounds like the 820 00:48:03,400 --> 00:48:05,320 Speaker 2: drugs are kind of being given out like candy. 821 00:48:05,600 --> 00:48:05,799 Speaker 4: Well. 822 00:48:05,880 --> 00:48:08,480 Speaker 3: The other thing that I think is something of a 823 00:48:08,600 --> 00:48:12,080 Speaker 3: tell is the fact that adderall is not licensed in 824 00:48:12,280 --> 00:48:15,480 Speaker 3: places like the UK. This seems in many respects to 825 00:48:15,560 --> 00:48:21,319 Speaker 3: be a sort of peculiarly or especially American phenomenon. 826 00:48:20,880 --> 00:48:22,560 Speaker 4: Which Tracy, Yes. 827 00:48:22,360 --> 00:48:23,879 Speaker 2: What do they do in the UK if they don't 828 00:48:23,920 --> 00:48:25,840 Speaker 2: get if they can't get ederall. 829 00:48:25,960 --> 00:48:28,279 Speaker 3: They get their energy. If you work in finance, you 830 00:48:28,320 --> 00:48:30,759 Speaker 3: get your energy the old fashioned way. I'm not gonna 831 00:48:30,800 --> 00:48:34,399 Speaker 3: say what that. I mean coffee of oh yes, uh no, 832 00:48:34,520 --> 00:48:37,440 Speaker 3: it's powdered coffee. Yeah, there we go. But I think 833 00:48:37,560 --> 00:48:40,799 Speaker 3: like it is suggestive as to what's going on here, 834 00:48:40,920 --> 00:48:44,160 Speaker 3: the fact that there might be something structural or specific 835 00:48:44,280 --> 00:48:46,920 Speaker 3: about the US economy or the healthcare system that seems 836 00:48:46,960 --> 00:48:48,200 Speaker 3: to be driving some of this. 837 00:48:48,600 --> 00:48:51,759 Speaker 2: Get two things on that. So Daniel made this point, 838 00:48:51,800 --> 00:48:55,080 Speaker 2: and I had realized this six months ago. I remember, 839 00:48:55,200 --> 00:48:58,080 Speaker 2: out of interest, trying to find some number about like 840 00:48:58,280 --> 00:49:00,840 Speaker 2: finding how much of a drug has been described, how 841 00:49:00,880 --> 00:49:03,960 Speaker 2: many doses prescribed? And you can't find it. And if 842 00:49:03,960 --> 00:49:07,200 Speaker 2: you look, the only entities that offer that data are 843 00:49:07,239 --> 00:49:09,520 Speaker 2: these like private for profit collectors, and you have to 844 00:49:09,520 --> 00:49:11,640 Speaker 2: pay like ten thousand dollars or whatever just for a 845 00:49:11,719 --> 00:49:14,520 Speaker 2: data set who try to aggregate, you know, how many 846 00:49:14,560 --> 00:49:18,239 Speaker 2: prescriptions of each and it's sort of this idea for 847 00:49:18,360 --> 00:49:21,160 Speaker 2: better or worse, and listeners can make up their mind. 848 00:49:21,440 --> 00:49:23,160 Speaker 2: But like, if you do have a sort of more 849 00:49:23,600 --> 00:49:29,120 Speaker 2: national healthcare system and there's only essentially one monopoly prescription writer, 850 00:49:29,239 --> 00:49:31,400 Speaker 2: whether it's the NHS or whatever it is they have 851 00:49:31,440 --> 00:49:33,879 Speaker 2: in Canada, then you know those numbers in real time 852 00:49:33,880 --> 00:49:35,680 Speaker 2: and you can say, oh my god, like these prescriptions 853 00:49:35,680 --> 00:49:36,560 Speaker 2: are totally exploding. 854 00:49:36,760 --> 00:49:39,200 Speaker 3: Yeah, that point by Danielle, the idea that maybe there 855 00:49:39,200 --> 00:49:42,840 Speaker 3: are data benefits to have a national healthcare service, that 856 00:49:42,960 --> 00:49:45,719 Speaker 3: was one I hadn't heard before. But it makes some 857 00:49:46,000 --> 00:49:48,200 Speaker 3: sense to have a sort of centralized body that is 858 00:49:48,239 --> 00:49:51,680 Speaker 3: actually writing these things, perhaps has a better outlook anyway, 859 00:49:51,800 --> 00:49:54,680 Speaker 3: fascinating conversation. You know it's going to be good when 860 00:49:54,760 --> 00:49:57,320 Speaker 3: you ask someone for context on this and they start 861 00:49:57,360 --> 00:49:59,799 Speaker 3: out with, you know, meth addiction in World War Two. 862 00:50:00,239 --> 00:50:03,080 Speaker 3: So I really enjoyed that conversation. I feel like I 863 00:50:03,160 --> 00:50:06,960 Speaker 3: have a better handle on a sort of cultural site 864 00:50:07,080 --> 00:50:09,800 Speaker 3: geist of the American economy. But wow, there are a 865 00:50:09,840 --> 00:50:12,320 Speaker 3: lot of questions that come out of this conversation. 866 00:50:12,680 --> 00:50:12,880 Speaker 4: You know. 867 00:50:12,960 --> 00:50:15,799 Speaker 2: One other thing too about this sort of maybe the 868 00:50:15,840 --> 00:50:19,520 Speaker 2: pathologies of the US healthcare system is I don't think 869 00:50:19,600 --> 00:50:22,200 Speaker 2: that any of these drugs are as bad as like 870 00:50:22,520 --> 00:50:25,520 Speaker 2: addictive painkillers. But it is striking to me that we 871 00:50:25,880 --> 00:50:28,799 Speaker 2: did just have this like huge, sort of multi year 872 00:50:29,000 --> 00:50:34,240 Speaker 2: realization that the opioid sellers that it was riven with abuse, 873 00:50:34,400 --> 00:50:36,560 Speaker 2: a lot of the same things about like so called 874 00:50:36,680 --> 00:50:40,760 Speaker 2: like nonprofit patient advocacy groups trying to make these drugs 875 00:50:40,800 --> 00:50:43,400 Speaker 2: more available and ease the regulations, and then we had 876 00:50:43,400 --> 00:50:47,000 Speaker 2: this big sort of national reckoning with it various books 877 00:50:47,040 --> 00:50:50,480 Speaker 2: and documentaries. Is such a disaster, and then we just 878 00:50:50,480 --> 00:50:52,560 Speaker 2: like move on to the next drug. And again I'm 879 00:50:52,560 --> 00:50:55,600 Speaker 2: not saying it's necessarily comparable, but the speed with which 880 00:50:55,640 --> 00:50:57,560 Speaker 2: we just sort of here's the new drug that we're 881 00:50:57,560 --> 00:51:01,239 Speaker 2: going to commercialize and promote aggressively, it's like, didn't we 882 00:51:01,360 --> 00:51:01,879 Speaker 2: just do this? 883 00:51:02,280 --> 00:51:02,520 Speaker 5: Well? 884 00:51:02,800 --> 00:51:05,080 Speaker 3: Danielle made that point to the idea that like it 885 00:51:05,200 --> 00:51:07,439 Speaker 3: kind of goes in cycles, all right, And it does 886 00:51:07,520 --> 00:51:09,880 Speaker 3: feel like these things kind of come and go in 887 00:51:09,960 --> 00:51:13,760 Speaker 3: terms of popularity, in terms of commercialization, as you mentioned 888 00:51:14,000 --> 00:51:17,040 Speaker 3: it is. Yeah, you're right, it's nuts, but it seems 889 00:51:17,080 --> 00:51:20,680 Speaker 3: like it is getting a little bit more attention nowadays. 890 00:51:20,719 --> 00:51:22,880 Speaker 3: We'll see what happens. We'll see shall we leave it there? 891 00:51:22,960 --> 00:51:23,719 Speaker 2: Let's leave it there. 892 00:51:23,920 --> 00:51:26,640 Speaker 3: This has been another episode of the All Blots podcast. 893 00:51:26,719 --> 00:51:29,680 Speaker 3: I'm Tracy Alloway. You can follow me at Tracy Alloway. 894 00:51:29,800 --> 00:51:32,600 Speaker 2: And I'm Joe Wisenthal. You can follow me at the Stalwart. 895 00:51:32,800 --> 00:51:37,480 Speaker 2: Follow our guest Danielle Carr, She's at Underscore Danielle Underscore Car. 896 00:51:37,719 --> 00:51:41,000 Speaker 2: Follow our producers Carmen Rodriguez at Carmen Arman, dash Ol 897 00:51:41,000 --> 00:51:44,440 Speaker 2: Bennett at Dashbot and Kilbrooks at Kilbrooks. Thank you to 898 00:51:44,480 --> 00:51:47,600 Speaker 2: our producer Moses Ondam. For more Oddlots content, go to 899 00:51:47,600 --> 00:51:50,200 Speaker 2: Bloomberg dot com slash odd Lots, where we have transcripts, 900 00:51:50,239 --> 00:51:52,799 Speaker 2: a blog and the newsletter and you can chat about 901 00:51:52,840 --> 00:51:54,759 Speaker 2: all of these topics twenty four to seven in the 902 00:51:54,800 --> 00:51:58,360 Speaker 2: discord with fellow listeners Discord dodgg slash Oddlines. 903 00:51:58,480 --> 00:52:00,400 Speaker 3: And if you enjoy All Blots, if you like it 904 00:52:00,400 --> 00:52:03,840 Speaker 3: when we do healthcare or pharma themed episodes, then please 905 00:52:03,920 --> 00:52:07,000 Speaker 3: leave us a positive review on your favorite podcast platform. 906 00:52:07,480 --> 00:52:10,280 Speaker 3: And remember, if you're a Bloomberg subscriber, you can listen 907 00:52:10,280 --> 00:52:13,360 Speaker 3: to all of our episodes absolutely ad free. All you 908 00:52:13,400 --> 00:52:16,839 Speaker 3: need to do is connect your Bloomberg account with Apple Podcasts. 909 00:52:17,080 --> 00:52:17,880 Speaker 3: Thanks for listening.