WEBVTT - I Drink Your Blood

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<v Speaker 1>Welcome to Stuff to Blow Your Mind from how Stuff

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<v Speaker 1>Works dot com. Hey, wasn't the Stuff to Blow your Mind?

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<v Speaker 1>My name is Robert Lamb and dot Joe McCormick, and hey,

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<v Speaker 1>it's Halloween season. Today's episode is kind of HALLOWEENI we

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<v Speaker 1>also want to remind you to feature to check out

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<v Speaker 1>Stuff to Blow your Mind dot com. That is, uh,

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<v Speaker 1>the main site. That's where you find all of the podcast,

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<v Speaker 1>all the videos of various blog posts. And we have

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<v Speaker 1>a two interesting things going on this month. Monster Science,

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<v Speaker 1>the video series that I've been doing in the past

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<v Speaker 1>here is coming back these last two weeks of October

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<v Speaker 1>four new episodes with the sort of vhs leyden Um

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<v Speaker 1>horror cinema themed explorations of science. All right, so let's

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<v Speaker 1>get rolling with this. I want to kick off by

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<v Speaker 1>just asking you. It's just a very basic question here, Joe.

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<v Speaker 1>Do you see yourself as you eventually enter old age?

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<v Speaker 1>Do you see yourself drinking the blood of the young

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<v Speaker 1>in order to sustaining your unnatural life? M Now, are

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<v Speaker 1>we're talking about the blood of the young human or

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<v Speaker 1>the blood of any young animal? I mean, I assume

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<v Speaker 1>the young deman. I mean that's where the vitality is.

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<v Speaker 1>That's what human life force is. If I'm going to

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<v Speaker 1>keep my own human life force going, that's a good

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<v Speaker 1>place to go, right it could be. But then again,

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<v Speaker 1>if we follow our our magical intuitions and the history

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<v Speaker 1>of our practices, I think animal blood rituals have been

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<v Speaker 1>fairly common in human history, right, yeah, and certainly not

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<v Speaker 1>only animal blood rights, but even into early pseudo scientific

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<v Speaker 1>ideas of of taking elements from particularly virile seeming specimens

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<v Speaker 1>and and using those tissues in our own body. You know,

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<v Speaker 1>I think I would feel rude drinking the blood of

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<v Speaker 1>young humans. But what I might do is a kind

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<v Speaker 1>of mithraic ritual where I would get into some contraption

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<v Speaker 1>and have a bull on a grate above me and

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<v Speaker 1>then just bathe in its showering blood as it is butchered. Okay, well, yeah,

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<v Speaker 1>that that was that way. It's not like the direct

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<v Speaker 1>bathing or the direct consumption of the blood. There's a

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<v Speaker 1>there's a buffer, a mythic buffer zone there. Yeah. Yeah, yeah,

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<v Speaker 1>And then of course you get all of the all

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<v Speaker 1>of the wonderful attributes to the bull, right, the strength,

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<v Speaker 1>the power, the virility, it's good stuff. Yeah, Or potentially

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<v Speaker 1>just like a bull Testies young person blood smoothie, that

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<v Speaker 1>that might end up being my like vampiric morning ritual

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<v Speaker 1>when I'm an old person. Now, Robert, obviously you brought

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<v Speaker 1>this up for a reason. Are are you thinking about

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<v Speaker 1>drinking blood anytime soon? Well? I can't help but think

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<v Speaker 1>about it a little bit, just based on some of

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<v Speaker 1>our the research we've been doing here, uh, some some

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<v Speaker 1>mythic research and historical research, and most importantly some modern

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<v Speaker 1>scientific research into the advantages of taking another individual's blood

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<v Speaker 1>into your own body. That that sounds like you're hedging there,

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<v Speaker 1>you know, so, so not necessarily always just drinking blood,

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<v Speaker 1>but but at least some way taking blood, taking someone's blood, Yeah,

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<v Speaker 1>I mean, because certainly there are various ways of of

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<v Speaker 1>of taking another individual's blood and gaining some sort of

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<v Speaker 1>life essence from it. Right, Probably the most notable mythological,

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<v Speaker 1>folkloric example of this, if not actual historical fact, is

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<v Speaker 1>that of Hungarian Countess Elizabeth Bathing Right, the blood Countess. Right,

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<v Speaker 1>So she was one according to the historical record, I mean,

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<v Speaker 1>we can never really know. She was apparently one of

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<v Speaker 1>the most prolific serial killers in human history. Yes, I mean,

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<v Speaker 1>we're talking to like six fifty victims during her reign,

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<v Speaker 1>and the charges level against we're pretty out there, right,

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<v Speaker 1>I mean, and that's one of the problems looking back

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<v Speaker 1>at it. To what extent are these uh, these charges

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<v Speaker 1>in Bellish, To what extent are they outright slander? Right? Right?

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<v Speaker 1>But at least what she was charged with was the

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<v Speaker 1>murder of hundreds of I think it was mostly young girls. Yes, Yeah,

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<v Speaker 1>there were charges that that young virsion girls were favorite victim. Yeah.

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<v Speaker 1>And the story goes that Countess Bathie feared aging, that

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<v Speaker 1>she didn't want to become old and shriveled and and

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<v Speaker 1>see her youth to evaporate before her eyes, and she

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<v Speaker 1>got a pretty interesting idea in her head what if

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<v Speaker 1>she could maintain her youth with the blood of the young. Again,

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<v Speaker 1>we we don't know to what extending Any of this

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<v Speaker 1>is history. A lot of it's probably just made up

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<v Speaker 1>legend about her. It is pretty certain, I think, I

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<v Speaker 1>think most historians think that she did really or was

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<v Speaker 1>involved in the killing of lots of young girls. But

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<v Speaker 1>you know, her motivations for it, and whether she actually

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<v Speaker 1>bathed in their blood or consume their blood or anything

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<v Speaker 1>like that that. I think that's a lot shakier. Yeah,

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<v Speaker 1>you don't really see many of any historians say yeah,

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<v Speaker 1>I think she actually bathed in the blood of virgins.

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<v Speaker 1>More likely they tend to run the gannet between she

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<v Speaker 1>was just a victim of conspiracy, uh, but was also

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<v Speaker 1>a part of a bread and murderous, an awful family

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<v Speaker 1>who Yeah, she was a really awful ruler who probably

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<v Speaker 1>got what was coming to her. So you can sort

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<v Speaker 1>of pick and choose and decide where you're gonna fall

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<v Speaker 1>in there. But the the idea, the myth of the

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<v Speaker 1>thing that the folkloric idea of this evil, rich ruler

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<v Speaker 1>uh bathing in a young person's blood in order to

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<v Speaker 1>stay young, that continues to resonate, and and of course

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<v Speaker 1>it also has various um racist and sexist qualities to

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<v Speaker 1>it as well. And besides from this, you know sort

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<v Speaker 1>of out the outskirts of Europe, Yeah, Eastern European. She's exotic,

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<v Speaker 1>she's dangerous, uh, And of course all she wants to

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<v Speaker 1>do is is a peer young. She's so vain and

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<v Speaker 1>so hateful towards those who actually have beauty and youth

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<v Speaker 1>that she would murder them and bathe in their blood.

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<v Speaker 1>Now there's a tangent about Elizabeth Bathory that I cannot resist.

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<v Speaker 1>It's not really related, but I remember back when I

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<v Speaker 1>was in high school, coming across it was either a

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<v Speaker 1>seat or a tape of a metal band called Bathory

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<v Speaker 1>that I thought was the funniest CD cover I've ever

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<v Speaker 1>seen because the bad calligraphy on the name Bathory made

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<v Speaker 1>it look like it said bat Lord. Wouldn't that be

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<v Speaker 1>a great metal band? That Lord sounds good too? And

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<v Speaker 1>also you know, vampirick and also so I like it. Uh. Now,

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<v Speaker 1>when we get into mythology and folklore, of course, there

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<v Speaker 1>are way too many examples of blood drinkers and vampireic creatures.

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<v Speaker 1>They're far too many examples of blood rituals to even

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<v Speaker 1>go into right there. Just it's a common trope throughout

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<v Speaker 1>human history. Um, we even had and we have so

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<v Speaker 1>many examples even of our own culture. One that came

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<v Speaker 1>to mind when we were talking the other day was

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<v Speaker 1>the nineteen seventies TV show called The Immortal. I've never

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<v Speaker 1>seen this. I only saw it because there was a

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<v Speaker 1>brief time in the late nineties, I think maybe the

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<v Speaker 1>early two thousands where they were showing reruns on the

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<v Speaker 1>Sci Fi Channel, and it was one of these shows

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<v Speaker 1>where it was like it was an ABC it was

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<v Speaker 1>an ABC Movie of the Week and then a very

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<v Speaker 1>brief television show that didn't take off, And it was

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<v Speaker 1>kind of from The Incredible Hulk mold. So you have

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<v Speaker 1>this going from town to town. Yeah, somebody's chasing him.

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<v Speaker 1>There's something this overarching plot of these people who are

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<v Speaker 1>after him. But then from in each town that he

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<v Speaker 1>goes to, he has this ability to help people or

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<v Speaker 1>their new sub villains to deal with. Also, like The

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<v Speaker 1>Incredible Hulk, he's got a power that's both a blessing

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<v Speaker 1>and a curse. Yes, So his his whole deal in

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<v Speaker 1>this show is that his blood uh is essentially kind

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<v Speaker 1>of magic, right, It's this wonderful, wonderful blood. In a

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<v Speaker 1>transfusion of this blood will basically wipe out any of

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<v Speaker 1>your illnesses and it can allow you to live longer.

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<v Speaker 1>So it's a it's it's it's a longevity uh drug

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<v Speaker 1>in this man's veins. It's like a biological anti virus program. Yeah.

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<v Speaker 1>And so of course there's a particular rich old dude

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<v Speaker 1>who wants nothing more than to just keep him closed

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<v Speaker 1>up in his mansion to himself, so he can just

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<v Speaker 1>have as much of his blood as he needs to

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<v Speaker 1>keep going and make him the mad Max blood bag

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<v Speaker 1>on the front of his car. Yeah yeah, right there

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<v Speaker 1>in the front of his limo. Uh so, but of

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<v Speaker 1>course the hero doesn't doesn't dig that, so he escapes,

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<v Speaker 1>he's on the run, and uh you know, it's a

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<v Speaker 1>it's a very nineteen seventies kind of an incredible Hulk delivery,

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<v Speaker 1>but it's kind of a cool idea and it definitely

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<v Speaker 1>ties in with a lot of the actual science we're

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<v Speaker 1>going to discuss later in the episode. Well, there there

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<v Speaker 1>are multiple ways that I think people would imagine blood

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<v Speaker 1>could have a power to rejuvenate, to invigorate, to give

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<v Speaker 1>you the strength of the young, and I think they

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<v Speaker 1>sort of occur along a scale of magical thinking. Like

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<v Speaker 1>on one hand, there's a much more straightforward, I think

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<v Speaker 1>material kind of approach to it, where you'd think, well,

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<v Speaker 1>there's something about young people's blood that gives them their

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<v Speaker 1>body strength, and so it must be nutritious in a way.

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<v Speaker 1>You know, you can imagine people wanting to consume it

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<v Speaker 1>with a with a fairly secular mindset, as long as

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<v Speaker 1>they don't know much about modern medicine. Um. But then

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<v Speaker 1>there's also the magical end where you start getting into

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<v Speaker 1>magical associative thinking, where where properties of a thing can

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<v Speaker 1>be absorbed by coming into contact with its essence. And

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<v Speaker 1>then you get into some of these funeral cannibal rights

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<v Speaker 1>where an individual will partake of the flesh of a

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<v Speaker 1>loved one after they have died in order to absorb

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<v Speaker 1>part of them. And then there's the whole realm of

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<v Speaker 1>what James Frasier called homeopathic magic, where light cures likes

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<v Speaker 1>and the thinking here would go that the blood of

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<v Speaker 1>the young must cure the old and turned back the clock,

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<v Speaker 1>because that's just that's what it is. That's the the

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<v Speaker 1>inherent nature of how how different properties interact with each other. Yeah,

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<v Speaker 1>So throughout the history of using homeopathic magical medicine, the

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<v Speaker 1>idea might be that you take a thing associated with

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<v Speaker 1>another thing to cure that second thing. So, you know,

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<v Speaker 1>if you had problems with your hand, you might consume

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<v Speaker 1>the paw of an animal or the hand of a

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<v Speaker 1>person or something like that, you know, or a problem

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<v Speaker 1>if you had headaches, you might consume ground up skull

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<v Speaker 1>or something like that. So yeah, if your if your

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<v Speaker 1>problem is aging, you can consume youth. And what is

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<v Speaker 1>the essence of youth more than the juice of young people?

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<v Speaker 1>Young people's blood. And another influence I can also think

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<v Speaker 1>of that might have made people over the centuries want

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<v Speaker 1>to imbibe the blood of the young in order to

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<v Speaker 1>avoid aging or to restore vigor and vitality, is the

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<v Speaker 1>sort of bodily humor thinking. You know that you had

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<v Speaker 1>the four temperaments that went along with the bodily humors theory,

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<v Speaker 1>and in that traditional order of temperaments, the sanguine temperament,

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<v Speaker 1>the one that's associated with blood is the one that's

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<v Speaker 1>like positive and excitable and high energy and playful. It's

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<v Speaker 1>still there in our language, like to be sanguine about

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<v Speaker 1>something is to be optimistic or positive about it. So

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<v Speaker 1>I don't know if that association within the body Humor's

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<v Speaker 1>theory is a symptom of this underlying association we have

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<v Speaker 1>between blood and then youth and vigor and vitality, or

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<v Speaker 1>if the association between blood and youth and vigor comes

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<v Speaker 1>from the bodily humor's theory. Yeah, that's that's an interesting take.

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<v Speaker 1>I hadn't thought about that. You know, another thing that

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<v Speaker 1>comes to mind, at least for the modern era, is

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<v Speaker 1>that since we we talked before about how we can't

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<v Speaker 1>help but think of ourselves and think of reality in

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<v Speaker 1>terms of whatever our technology is. So uh, you know,

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<v Speaker 1>for a while, certainly in the industrial age, we've we've

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<v Speaker 1>looked at the body as biomechanical, and here we're having

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<v Speaker 1>to deal with all our automobiles, and what do you

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<v Speaker 1>have to do with your automobile? You have to take

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<v Speaker 1>out the old oil, right and get some new oil

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<v Speaker 1>in there. So maybe on a subliminal level, even a

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<v Speaker 1>subconscious level, rather we end up thinking of of ourselves

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<v Speaker 1>as an automobile and like, well, maybe I'm just filled

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<v Speaker 1>with all this old oil, and what if I could

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<v Speaker 1>get that old oil out and get a you know,

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<v Speaker 1>a a transfusion of new oil. Yeah, So I could

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<v Speaker 1>see where we might buy into the concept, um, Yeah,

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<v Speaker 1>at a subconscious level, just based on our technology. And

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<v Speaker 1>it's also of course easy to to think of it

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<v Speaker 1>just as pure metaphor, right, because we're we're surrounded by

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<v Speaker 1>you know, largely youth obsessed culture. You see plenty of

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<v Speaker 1>examples of of middle age and older individuals who is

0:12:26.559 --> 0:12:29.880
<v Speaker 1>grasping after that youth right made sometimes quite literally in

0:12:29.880 --> 0:12:34.280
<v Speaker 1>the form of rich old men with very young romantic partners. Now,

0:12:34.400 --> 0:12:36.320
<v Speaker 1>I can't remember where I read this. I think it

0:12:36.400 --> 0:12:38.320
<v Speaker 1>was in one of our sources, maybe let me know,

0:12:38.679 --> 0:12:43.760
<v Speaker 1>But there was a suggestion that the idea of grasping

0:12:43.800 --> 0:12:47.920
<v Speaker 1>back after youth might also be a fairly recent thing

0:12:48.559 --> 0:12:51.400
<v Speaker 1>in the history of humanity, because it's only recently that

0:12:51.520 --> 0:12:55.040
<v Speaker 1>humans have begun to regularly live to old age. In

0:12:55.120 --> 0:12:57.880
<v Speaker 1>some parts of the world, I mean, more often there

0:12:57.920 --> 0:13:01.160
<v Speaker 1>was high infant mortality, more people side in middle age

0:13:01.280 --> 0:13:04.240
<v Speaker 1>or younger. Uh, And now it's pretty common that if

0:13:04.280 --> 0:13:07.520
<v Speaker 1>you have access to good, high quality medical care, you

0:13:07.559 --> 0:13:11.079
<v Speaker 1>can usually live to a decently long age. Well, that's

0:13:11.120 --> 0:13:13.840
<v Speaker 1>that's an interesting take on it there too. Yeah. Yeah,

0:13:13.840 --> 0:13:16.199
<v Speaker 1>so maybe that is kind of something we should have

0:13:16.200 --> 0:13:20.000
<v Speaker 1>looped in with the biomechanical body as a more modern

0:13:20.120 --> 0:13:24.600
<v Speaker 1>view on on vampiod diets. Now, before we really get

0:13:24.640 --> 0:13:26.560
<v Speaker 1>into the topic, though, we probably just have to talk

0:13:26.600 --> 0:13:30.360
<v Speaker 1>about the consumption of blood as a food, like what

0:13:30.440 --> 0:13:32.959
<v Speaker 1>does that mean? What does that entail? And it's a

0:13:33.040 --> 0:13:37.040
<v Speaker 1>it's pretty interesting, uh, to stop and study that, particularly

0:13:37.080 --> 0:13:41.000
<v Speaker 1>when you look at animals that are obligate. Sango VORs

0:13:41.120 --> 0:13:44.280
<v Speaker 1>that that feed exclusively on blood, like the vampire bat

0:13:44.559 --> 0:13:49.520
<v Speaker 1>say that category again obligates, So that's great blood only.

0:13:49.640 --> 0:13:51.200
<v Speaker 1>They go to the they go to the restaurant. They

0:13:51.200 --> 0:13:53.920
<v Speaker 1>need to see the blood only menu. They're not gonna

0:13:53.920 --> 0:13:56.320
<v Speaker 1>eat the salad. They're not gonna eat the steak. It's

0:13:56.400 --> 0:13:59.600
<v Speaker 1>just the blood. That's the corner that they've they've painted

0:13:59.600 --> 0:14:03.840
<v Speaker 1>themselves into evolutionarily, well, from a lay person's point of view,

0:14:03.840 --> 0:14:06.640
<v Speaker 1>it would seem like blood would be a perfectly nutritious thing.

0:14:06.640 --> 0:14:08.880
<v Speaker 1>I mean, the conventional wisdom is that the blood is

0:14:08.920 --> 0:14:11.360
<v Speaker 1>the life, right, Yeah, I mean it's the life, it's

0:14:11.400 --> 0:14:14.040
<v Speaker 1>the life blood. This is the stuff itself. This is

0:14:14.080 --> 0:14:18.640
<v Speaker 1>like the pure essence. This is like humanity straight. Yeah,

0:14:18.800 --> 0:14:22.040
<v Speaker 1>you think that's kind of ore the magical mythic realm

0:14:22.080 --> 0:14:25.040
<v Speaker 1>to it. But when you actually look at something like

0:14:25.080 --> 0:14:28.600
<v Speaker 1>a vampire bat um and you look at its consumption

0:14:28.600 --> 0:14:31.360
<v Speaker 1>of blood, I mean it's basically consuming protein and water.

0:14:31.440 --> 0:14:34.480
<v Speaker 1>There's there's no fat for the bat to store away,

0:14:34.880 --> 0:14:38.920
<v Speaker 1>So unlike their insect and fruit eating kin, they can't hibernate,

0:14:38.960 --> 0:14:42.200
<v Speaker 1>they can't migrate because they lack the fat stores. Instead,

0:14:42.200 --> 0:14:45.560
<v Speaker 1>they have to feed every night, lapping up to their

0:14:45.560 --> 0:14:50.160
<v Speaker 1>body weight in order to survive, and um, it sounds

0:14:50.200 --> 0:14:55.000
<v Speaker 1>like a very difficult limited diet. Yeah. Yeah, And and

0:14:55.320 --> 0:14:57.000
<v Speaker 1>there are a lot of fascinating theories about how it

0:14:57.000 --> 0:14:59.960
<v Speaker 1>occurred that they may have started out feeding on parasite

0:15:00.520 --> 0:15:04.080
<v Speaker 1>that contain the blood, and then eventually that they decided

0:15:04.240 --> 0:15:07.240
<v Speaker 1>weren't decided. Eventually they evolve more in the direction of

0:15:07.280 --> 0:15:10.000
<v Speaker 1>feeding exclusively and directly on the blood, as opposed to

0:15:10.040 --> 0:15:12.520
<v Speaker 1>the creatures that feed on blood. Oh, interesting, how an

0:15:12.520 --> 0:15:15.560
<v Speaker 1>intermediary could come in there? What was that story I

0:15:15.600 --> 0:15:17.960
<v Speaker 1>was reading about a while back about there's a particular

0:15:18.000 --> 0:15:21.960
<v Speaker 1>species of African jumping spider that likes human blood but

0:15:22.080 --> 0:15:25.440
<v Speaker 1>not drinking it directly from humans, right, praise on mosquitoes

0:15:25.440 --> 0:15:27.440
<v Speaker 1>that contain it. Yeah, so it's the same, the same

0:15:27.480 --> 0:15:30.520
<v Speaker 1>sort of situation where yeah, eventually you just give up

0:15:30.520 --> 0:15:33.240
<v Speaker 1>the middleman and just going straight for this might come

0:15:33.320 --> 0:15:36.880
<v Speaker 1>straight to us. Yeah, And so that's one of the

0:15:36.920 --> 0:15:41.280
<v Speaker 1>reasons that it's hard to imagine a human feeding exclusively

0:15:41.320 --> 0:15:43.600
<v Speaker 1>on blood to get into or even even a humanoid

0:15:44.040 --> 0:15:48.400
<v Speaker 1>certainly a larger creature, just because the energy levels required.

0:15:48.600 --> 0:15:52.240
<v Speaker 1>But we know fully well that humans do sometimes consume blood,

0:15:52.240 --> 0:15:54.960
<v Speaker 1>don't they. I mean, I I have seen a blood sausage,

0:15:54.960 --> 0:15:56.960
<v Speaker 1>but I don't think I've ever eaten one. I don't

0:15:56.960 --> 0:15:59.360
<v Speaker 1>know that I have either, unless, I mean, after I

0:15:59.720 --> 0:16:02.080
<v Speaker 1>would reading about it, I thought, well, maybe I've had

0:16:02.080 --> 0:16:04.480
<v Speaker 1>it on an airplane. It didn't realize it because I've

0:16:04.560 --> 0:16:09.040
<v Speaker 1>like I've flown some some some particularly some Asian airlines

0:16:09.120 --> 0:16:11.000
<v Speaker 1>before where there's like some sort of a sausage meat

0:16:11.040 --> 0:16:14.200
<v Speaker 1>that I couldn't identify looking at pictures. Maybe that was

0:16:14.240 --> 0:16:17.400
<v Speaker 1>blood sausage. I don't know, but you see some version

0:16:17.440 --> 0:16:21.200
<v Speaker 1>of blood sausage in a lot of different cultures, and uh,

0:16:21.560 --> 0:16:24.800
<v Speaker 1>including I was. I found this interesting. The red tofu

0:16:25.040 --> 0:16:28.640
<v Speaker 1>found in some parts of China, the blood tofu blood tofuu. Yeah,

0:16:28.680 --> 0:16:31.360
<v Speaker 1>it's made from like pigs blood or something. Yeah, so

0:16:31.440 --> 0:16:34.800
<v Speaker 1>it's not not really tofu. So any any vegetarians out

0:16:34.800 --> 0:16:37.120
<v Speaker 1>there see that on the menu, you might, and you know,

0:16:37.160 --> 0:16:39.800
<v Speaker 1>ask a few questions about it before you order it. Uh.

0:16:39.800 --> 0:16:43.040
<v Speaker 1>And then of course there are various blood festivals. There's

0:16:43.040 --> 0:16:46.120
<v Speaker 1>a Nepalese Yak blood festival in which they drink blood.

0:16:46.120 --> 0:16:49.440
<v Speaker 1>They are various traditions throughout the world. Where blood is

0:16:49.880 --> 0:16:53.800
<v Speaker 1>consumed directly as sort of a culinary ritual. And certainly

0:16:54.120 --> 0:16:56.840
<v Speaker 1>in the American tradition, what everyone the whole thing is

0:16:56.840 --> 0:16:59.240
<v Speaker 1>to have a big rare steak, right, And certainly that

0:16:59.360 --> 0:17:02.760
<v Speaker 1>is blood leaking out of that meat. You know, I've

0:17:02.800 --> 0:17:04.840
<v Speaker 1>heard that all my life, but I think I've actually

0:17:04.880 --> 0:17:08.320
<v Speaker 1>read recently that that is not true. That the that

0:17:08.480 --> 0:17:11.480
<v Speaker 1>a the like the meat you would buy package the

0:17:11.560 --> 0:17:14.520
<v Speaker 1>grocery store, is mostly drained of blood. There's really not

0:17:14.560 --> 0:17:16.960
<v Speaker 1>going to be much blood in it. Uh. And that

0:17:17.080 --> 0:17:19.480
<v Speaker 1>when you cut into a bloody steak, you know, like

0:17:19.520 --> 0:17:22.160
<v Speaker 1>a nice rare steak, and all that red liquid comes out,

0:17:22.240 --> 0:17:24.760
<v Speaker 1>that's mostly just a mixture of water and then some

0:17:24.800 --> 0:17:28.560
<v Speaker 1>other protein. I think it might have been myoglobin. Okay, well,

0:17:28.600 --> 0:17:31.159
<v Speaker 1>you know, maybe I'm thrown off here by vampire movies

0:17:31.200 --> 0:17:34.600
<v Speaker 1>in which like a newly turned vampire starts sucking steaks

0:17:34.960 --> 0:17:37.520
<v Speaker 1>to stay alive. I feel like that trope has shown up,

0:17:38.200 --> 0:17:41.720
<v Speaker 1>I think inhabit and perhaps in Chronos as well. I

0:17:41.760 --> 0:17:44.920
<v Speaker 1>can't remember Chronos. That's a great one. So yeah, maybe

0:17:45.000 --> 0:17:47.320
<v Speaker 1>maybe this is an example of my my knowledge is

0:17:47.359 --> 0:17:51.280
<v Speaker 1>that has based more fiction than reality. But but either way,

0:17:51.640 --> 0:17:55.280
<v Speaker 1>humans have not been averse to consuming blood throughout history

0:17:55.320 --> 0:17:59.200
<v Speaker 1>as part of their diet, but not exclusively. Well, now

0:17:59.200 --> 0:18:02.119
<v Speaker 1>that leads us to just again the idea of medicinal

0:18:02.160 --> 0:18:05.280
<v Speaker 1>consumption of blood. Occasional consumption of blood is part of

0:18:05.720 --> 0:18:10.439
<v Speaker 1>some actual treatment of malady or illness, or just some

0:18:10.520 --> 0:18:14.400
<v Speaker 1>sort of a ritualistic practice, and there are a number

0:18:14.400 --> 0:18:17.320
<v Speaker 1>of cool examples of this. Drawing up most of these

0:18:17.320 --> 0:18:20.359
<v Speaker 1>examples from two different sources here, there's an excellent article

0:18:20.480 --> 0:18:24.840
<v Speaker 1>by Maria Dolan from Smithsonian Magazine titled The Gruesome History

0:18:24.840 --> 0:18:27.440
<v Speaker 1>of Eating corpses as Medicine, and of course that goes

0:18:27.480 --> 0:18:29.400
<v Speaker 1>into a lot more than just blood consumption, but also

0:18:29.480 --> 0:18:32.040
<v Speaker 1>flesh consumption. Is great article. I'll include a link to

0:18:32.040 --> 0:18:34.080
<v Speaker 1>it on the landing page for this episode. And there's

0:18:34.119 --> 0:18:38.199
<v Speaker 1>also another great article, Young Blood, by Jess Zimmerman writing

0:18:38.200 --> 0:18:41.360
<v Speaker 1>for Ian Magazine. I really liked both of these articles too,

0:18:41.400 --> 0:18:44.480
<v Speaker 1>that were great reads. But yeah, so some of the facts.

0:18:44.520 --> 0:18:48.879
<v Speaker 1>According to a description by Plenty the Elder, who is

0:18:48.920 --> 0:18:54.040
<v Speaker 1>a Roman historian, apparently Romans loved to drink the blood

0:18:54.200 --> 0:18:57.800
<v Speaker 1>of gladiators who were killed in the arena in ancient Rome,

0:18:58.440 --> 0:19:01.120
<v Speaker 1>so you'd have people down there. It out. I guess

0:19:01.200 --> 0:19:03.320
<v Speaker 1>one of them gets skewered with one of those little

0:19:03.320 --> 0:19:06.880
<v Speaker 1>pokey pokey Roman swords, the blood starts to come out,

0:19:06.920 --> 0:19:09.400
<v Speaker 1>and people just be like, give me some don't count

0:19:09.440 --> 0:19:11.639
<v Speaker 1>out the trident, dude. I always like to try it

0:19:11.760 --> 0:19:14.560
<v Speaker 1>ent and that guy, to whatever extent, that was actually

0:19:14.760 --> 0:19:17.200
<v Speaker 1>a thing and not just an artistic motif. But I

0:19:17.200 --> 0:19:19.080
<v Speaker 1>always I was always rooting for him because he had

0:19:19.200 --> 0:19:21.680
<v Speaker 1>more of the uphill battle. Yeah, I guess so. Yeah,

0:19:22.160 --> 0:19:26.680
<v Speaker 1>I would drink his blood because clearly he's he's he's smart, powerful,

0:19:26.680 --> 0:19:29.320
<v Speaker 1>but smart. Yeah, so that's what I want before I

0:19:29.320 --> 0:19:32.280
<v Speaker 1>go into podcasts. Again, I'm not sure exactly where this

0:19:32.359 --> 0:19:35.800
<v Speaker 1>falls on that scale I talked about earlier, like the

0:19:35.560 --> 0:19:39.040
<v Speaker 1>the sort of secular this is some kind of material

0:19:39.160 --> 0:19:42.879
<v Speaker 1>nutrition thinking to the magical I'm gaining the power and

0:19:43.119 --> 0:19:46.800
<v Speaker 1>essence of the gladiator thinking, I'd imagine this falls more

0:19:46.880 --> 0:19:50.879
<v Speaker 1>to the magical side, right, Yeah, I would think so. Um,

0:19:50.920 --> 0:19:53.240
<v Speaker 1>And it seems like it based on what I was reading.

0:19:53.280 --> 0:19:57.520
<v Speaker 1>It may have its roots in Truscan funeral rights, so

0:19:57.680 --> 0:20:01.000
<v Speaker 1>it may go beyond just you know, the near near

0:20:01.040 --> 0:20:03.760
<v Speaker 1>bloodthirsty aspect of the culture at the time. And I've

0:20:03.800 --> 0:20:06.800
<v Speaker 1>also read there's a two thousand three paper title between

0:20:06.880 --> 0:20:10.560
<v Speaker 1>Horror and Hope Gladiator's blood as a cure for UH

0:20:10.680 --> 0:20:13.520
<v Speaker 1>epileptics in Ancient Medicine, And this is published in the

0:20:13.600 --> 0:20:19.879
<v Speaker 1>Journal of Historical Neuroscience. And this article posited that spontaneous

0:20:19.880 --> 0:20:23.639
<v Speaker 1>recovery from some forms of epilepsy may be responsible for

0:20:23.680 --> 0:20:28.560
<v Speaker 1>the illusion of therapeutic effectiveness UH from drinking the blood

0:20:28.600 --> 0:20:30.600
<v Speaker 1>of a gladiator. So it's one of those things where

0:20:30.760 --> 0:20:33.640
<v Speaker 1>it seemed to work enough of the time, so why

0:20:33.680 --> 0:20:35.880
<v Speaker 1>not because it's also it's just it's just good fun.

0:20:36.000 --> 0:20:37.919
<v Speaker 1>It's just part of the part of going out on

0:20:37.960 --> 0:20:41.199
<v Speaker 1>the town and enjoying a gladiatorial contest. Well, yeah, the

0:20:41.200 --> 0:20:44.320
<v Speaker 1>false cure working by this method, I think was a

0:20:44.359 --> 0:20:47.400
<v Speaker 1>common feature of ancient medicine. You always read about these

0:20:47.400 --> 0:20:50.879
<v Speaker 1>types of medicines that that ancient people's thought would be

0:20:50.920 --> 0:20:54.359
<v Speaker 1>effective at curing X, Y or Z, when we now know,

0:20:54.960 --> 0:20:56.720
<v Speaker 1>you know, this has no effect at all. Why do

0:20:56.800 --> 0:21:00.199
<v Speaker 1>people think this? What might have happened really often is

0:21:00.240 --> 0:21:04.840
<v Speaker 1>that somebody took some of this in an unrelated way.

0:21:04.880 --> 0:21:07.439
<v Speaker 1>They just got better and it's like, look, it worked,

0:21:07.920 --> 0:21:10.640
<v Speaker 1>or they might have received a placebo effect boost from

0:21:10.720 --> 0:21:15.400
<v Speaker 1>from obtaining it. And then likewise, since uh, either they

0:21:15.440 --> 0:21:18.480
<v Speaker 1>had to pay a certain amount to obtain this gladiator

0:21:18.520 --> 0:21:20.480
<v Speaker 1>blood or it was such a big deal to get

0:21:20.520 --> 0:21:24.359
<v Speaker 1>it that you end up tweaking your memories enough to where,

0:21:24.359 --> 0:21:26.840
<v Speaker 1>of course it was a gladiator blood. I didn't drink

0:21:26.920 --> 0:21:31.240
<v Speaker 1>the blood of a dead slave and not benefit from

0:21:31.240 --> 0:21:33.560
<v Speaker 1>it and a monster, do you think, I am? No, no, no,

0:21:33.680 --> 0:21:35.840
<v Speaker 1>that that makes sense too, because we you know, we

0:21:36.040 --> 0:21:39.359
<v Speaker 1>go through all kinds of mental justification to justify things

0:21:39.359 --> 0:21:41.239
<v Speaker 1>that were difficult to get. So if you spend a

0:21:41.240 --> 0:21:44.760
<v Speaker 1>lot of money on appliance or a piece of furniture,

0:21:44.840 --> 0:21:47.200
<v Speaker 1>you end up coming up with ways of thinking this

0:21:47.280 --> 0:21:50.080
<v Speaker 1>was a good investment. The same could be true some

0:21:50.160 --> 0:21:54.280
<v Speaker 1>gladiator blood. I'm quite sure. So we we see this

0:21:54.280 --> 0:21:56.199
<v Speaker 1>trend throughout history, and we're gonna roll through some of

0:21:56.200 --> 0:21:59.240
<v Speaker 1>the examples, and some of these you're gonna get into

0:21:59.800 --> 0:22:04.920
<v Speaker 1>a very alleged territory because it's a popular motif as well,

0:22:05.200 --> 0:22:08.840
<v Speaker 1>to slander your enemy by saying they drink your people ahead. Yeah,

0:22:08.960 --> 0:22:12.080
<v Speaker 1>quite common in fact. Like so, one example would be

0:22:12.320 --> 0:22:16.879
<v Speaker 1>Pope Innocent the Eighth who died in fourtwo, and the

0:22:17.359 --> 0:22:19.720
<v Speaker 1>story is that he was one of the first people

0:22:19.840 --> 0:22:24.000
<v Speaker 1>to receive an attempted blood transfusion. But I think the

0:22:24.040 --> 0:22:26.119
<v Speaker 1>stories seemed to be all over the place. It's like

0:22:26.680 --> 0:22:30.080
<v Speaker 1>some say that he got blood from willing donors, or

0:22:30.119 --> 0:22:34.600
<v Speaker 1>that he drank the blood of Jewish children, or yeah, yeah,

0:22:34.720 --> 0:22:38.480
<v Speaker 1>sort of a reverse of the blood libel often leveled

0:22:38.520 --> 0:22:42.280
<v Speaker 1>against Jews in medieval times, saying that they're they're they're

0:22:42.359 --> 0:22:46.280
<v Speaker 1>drinking the blood of of of gentile children or processing

0:22:46.280 --> 0:22:49.760
<v Speaker 1>it into some sort of abait good. Yeah. So so

0:22:50.640 --> 0:22:53.720
<v Speaker 1>obviously that was not true with Pope Innocent the Eighth.

0:22:53.720 --> 0:22:57.520
<v Speaker 1>I'd say grain AsSalt there, yeah, yeah, and not just

0:22:57.560 --> 0:23:00.439
<v Speaker 1>as a flavor, the blood of the young boy. No, no,

0:23:00.440 --> 0:23:03.320
<v Speaker 1>no drinking. But but obviously the idea there was that

0:23:03.359 --> 0:23:06.640
<v Speaker 1>while you had an ailing, dying pope, maybe giving them

0:23:06.680 --> 0:23:10.640
<v Speaker 1>the blood of someone younger could help stave off death, right, yeah,

0:23:10.840 --> 0:23:13.640
<v Speaker 1>And of course you have various um minds that are

0:23:14.040 --> 0:23:18.720
<v Speaker 1>that are chiming in on this. Fifteenth century philosopher Marsilio

0:23:18.840 --> 0:23:22.439
<v Speaker 1>Ficino suggested drinking blood from the arm of a young person,

0:23:23.200 --> 0:23:27.000
<v Speaker 1>might I give you a health boost? So so you

0:23:27.040 --> 0:23:30.159
<v Speaker 1>have that to to boost you or to encourage you

0:23:30.240 --> 0:23:35.080
<v Speaker 1>to try it. So I assume I still living young person. Um, well,

0:23:35.119 --> 0:23:37.400
<v Speaker 1>you know they're young people. So unless you're just you're

0:23:37.520 --> 0:23:41.080
<v Speaker 1>lucky and they're not, you're probably gaining it from a

0:23:41.080 --> 0:23:42.920
<v Speaker 1>young person. Also, you know they're young people. They don't

0:23:42.960 --> 0:23:45.320
<v Speaker 1>have a lot of money. Maybe they want to make

0:23:45.320 --> 0:23:47.520
<v Speaker 1>a few bucks on the side by draining a little

0:23:47.560 --> 0:23:51.760
<v Speaker 1>blood off into a into a little uh little glass

0:23:51.800 --> 0:23:55.159
<v Speaker 1>for a little goblet for elderly members of the society.

0:23:55.240 --> 0:23:58.280
<v Speaker 1>I find the arm specification here kind of funny, like

0:23:58.440 --> 0:24:00.800
<v Speaker 1>is that just an accident? End have said, well, the

0:24:00.800 --> 0:24:02.520
<v Speaker 1>easiest place to get it is from the arm or

0:24:02.560 --> 0:24:05.800
<v Speaker 1>did the arm matter? To him? Was like, now if

0:24:05.800 --> 0:24:08.840
<v Speaker 1>you drink it from there, from their butt cheek, you're

0:24:08.920 --> 0:24:11.919
<v Speaker 1>not going to get the same restorative power. Well, he

0:24:12.000 --> 0:24:14.880
<v Speaker 1>must be referring to to obtaining it from a young,

0:24:15.200 --> 0:24:18.400
<v Speaker 1>probably willing person here, and then they're not draining them

0:24:18.480 --> 0:24:21.400
<v Speaker 1>whole because yeah, the arm is far enough away from

0:24:21.440 --> 0:24:24.720
<v Speaker 1>your center of being. It's it's it's not close to anything.

0:24:24.920 --> 0:24:29.480
<v Speaker 1>Uh that's too important, so yeah. Yeah. And then of course,

0:24:29.560 --> 0:24:32.120
<v Speaker 1>up through the Renaissance, you you still had all these

0:24:32.119 --> 0:24:35.760
<v Speaker 1>beliefs that consuming the flesh or the blood of humans

0:24:35.760 --> 0:24:38.840
<v Speaker 1>in various ways could cure all kinds of diseases, right,

0:24:39.720 --> 0:24:43.840
<v Speaker 1>Oh yeah, yeah, sixteen and seventeenth century, you had many Europeans,

0:24:44.080 --> 0:24:47.560
<v Speaker 1>including royalty priests, even scientists of the day that are

0:24:47.800 --> 0:24:50.399
<v Speaker 1>that are trying remedies that are made from human bone,

0:24:50.680 --> 0:24:54.040
<v Speaker 1>from fat, or from blood. Uh, in order to treat

0:24:54.080 --> 0:24:56.840
<v Speaker 1>everything from headache to epilepsy. And despite some of the

0:24:56.840 --> 0:24:59.040
<v Speaker 1>science we're gonna get into later in this episode, I

0:24:59.080 --> 0:25:04.119
<v Speaker 1>think we can assume probably none of that actually worked. Um,

0:25:04.200 --> 0:25:06.720
<v Speaker 1>let's see some other points here. At sixteenth century Italian

0:25:06.800 --> 0:25:11.400
<v Speaker 1>alchemist recommended taking children under the age of thirteen, shutting

0:25:11.440 --> 0:25:14.240
<v Speaker 1>them in a well enclosed room, sizening out the air

0:25:15.200 --> 0:25:18.119
<v Speaker 1>which would be quote filled with the breath and expired

0:25:18.200 --> 0:25:22.240
<v Speaker 1>substance of these five young virgins there for curative powers.

0:25:22.400 --> 0:25:25.880
<v Speaker 1>But again this is an alchemist, so yeah again grain

0:25:25.920 --> 0:25:28.719
<v Speaker 1>of salt. And of course through all these different rituals

0:25:28.720 --> 0:25:30.760
<v Speaker 1>that come up, the blood needs to be fresh, you needs.

0:25:31.600 --> 0:25:34.159
<v Speaker 1>It's not just a matter of finding a dead body

0:25:34.240 --> 0:25:36.480
<v Speaker 1>and draining it like the body needs either needs to

0:25:36.480 --> 0:25:41.280
<v Speaker 1>be still alive or very very very quickly exterminated. So

0:25:41.320 --> 0:25:44.280
<v Speaker 1>there you can think of the gladiatorial arena. Of course,

0:25:44.400 --> 0:25:46.560
<v Speaker 1>you've got somebody killed right there in front of you,

0:25:46.640 --> 0:25:50.760
<v Speaker 1>so you know it's fresh. Or you could go to

0:25:50.840 --> 0:25:53.600
<v Speaker 1>the other route, of the less valorous route, and stand

0:25:53.600 --> 0:25:56.800
<v Speaker 1>around waiting for a prisoner to be executed. Ah. Yes,

0:25:56.840 --> 0:25:59.080
<v Speaker 1>and here we see this, this tradition of the of

0:25:59.119 --> 0:26:02.480
<v Speaker 1>the gladiators blood being carried on really into two fairly

0:26:03.080 --> 0:26:08.400
<v Speaker 1>recent times. UM. I was reading one of the sources

0:26:08.440 --> 0:26:11.439
<v Speaker 1>here of that article by Maria Dolan Smithsonian said that

0:26:11.880 --> 0:26:15.160
<v Speaker 1>in nineteen o eight we saw the last known attempt

0:26:15.560 --> 0:26:19.719
<v Speaker 1>made in Germany to swallow blood from a an executed

0:26:20.119 --> 0:26:23.920
<v Speaker 1>criminal at the scaffold. Because for for a long time,

0:26:24.720 --> 0:26:26.480
<v Speaker 1>apparently this was the thing. You would go to an

0:26:26.520 --> 0:26:29.640
<v Speaker 1>execution and you drop a few coins for a cup

0:26:29.720 --> 0:26:32.760
<v Speaker 1>of still warm blood from the executed Because the executioner

0:26:33.080 --> 0:26:36.639
<v Speaker 1>he's kind of a magical boundary walker right between life

0:26:36.640 --> 0:26:41.440
<v Speaker 1>and death, between accepted society and the outside. Often he's

0:26:41.440 --> 0:26:45.000
<v Speaker 1>wearing a hood, right, and so this is where where

0:26:45.040 --> 0:26:46.720
<v Speaker 1>you can go to him. He's a master of life

0:26:46.720 --> 0:26:48.040
<v Speaker 1>and death, so he can give you some of the

0:26:48.480 --> 0:26:51.760
<v Speaker 1>juice of life and death. Um. And again they're no

0:26:51.800 --> 0:26:54.440
<v Speaker 1>more gladiatorial contest. This is your best bet at getting

0:26:54.440 --> 0:26:58.640
<v Speaker 1>a young person's blood, because because that's the best kind.

0:26:58.680 --> 0:27:00.879
<v Speaker 1>You gotta get the young virgin nor the young man's

0:27:00.840 --> 0:27:03.800
<v Speaker 1>so the virile young blood, that's where the magic is. Yeah,

0:27:03.840 --> 0:27:06.919
<v Speaker 1>and along those lines, I think sometimes people recommended trying

0:27:06.920 --> 0:27:09.159
<v Speaker 1>to get blood from people who were still alive. I

0:27:09.160 --> 0:27:11.479
<v Speaker 1>guess like we were talking about was probably meant by

0:27:11.480 --> 0:27:13.919
<v Speaker 1>the arm and the young person earlier. But people like

0:27:14.040 --> 0:27:19.760
<v Speaker 1>paracelsis where we're suggesting that you should should drink fresh blood. Right, Yeah,

0:27:19.840 --> 0:27:24.199
<v Speaker 1>sixteenth century Germans with physician general Renaissance man, you know,

0:27:24.320 --> 0:27:28.239
<v Speaker 1>just hit his hands and everything, great Renaissance weirdo. And

0:27:28.280 --> 0:27:30.880
<v Speaker 1>he believed yet the blood was probably good for drinking.

0:27:30.920 --> 0:27:33.159
<v Speaker 1>And it was one of his followers that took this

0:27:33.280 --> 0:27:35.399
<v Speaker 1>even further by suggesting that you take blood from a

0:27:35.440 --> 0:27:39.200
<v Speaker 1>living body. And again there there there's a tradition here

0:27:39.280 --> 0:27:44.760
<v Speaker 1>of of learned men at least contemplating the prospect. Leonardo

0:27:44.800 --> 0:27:47.359
<v Speaker 1>da Vinci said, we preserve our life with the death

0:27:47.400 --> 0:27:50.520
<v Speaker 1>of others in a dead thing in since a life remains,

0:27:50.600 --> 0:27:53.760
<v Speaker 1>which when it is reunited with the stomachs of the living,

0:27:54.080 --> 0:27:59.360
<v Speaker 1>regains sensitive and intellectual life. That's an interesting take on digestion. Yeah,

0:27:59.600 --> 0:28:02.240
<v Speaker 1>so I'm the sources are there. You have some you have,

0:28:02.640 --> 0:28:05.920
<v Speaker 1>you have learned men who are talking about the potential

0:28:06.160 --> 0:28:10.359
<v Speaker 1>benefits of drinking blood. You have rituals and rights throughout history,

0:28:10.440 --> 0:28:13.040
<v Speaker 1>so it continues to seem to make a certain amount

0:28:13.080 --> 0:28:17.200
<v Speaker 1>of sense. Of course, if freshness isn't quite so necessary

0:28:17.200 --> 0:28:19.280
<v Speaker 1>to you, you could probably just work it into some

0:28:19.400 --> 0:28:22.640
<v Speaker 1>various recipes, right, you can make a marmalade out of it. Yeah,

0:28:22.640 --> 0:28:26.439
<v Speaker 1>apparently there was a Franciscan apothecary recipe from sixteen seventy

0:28:26.520 --> 0:28:32.760
<v Speaker 1>nine for a human blood based marmalade um. And as

0:28:32.840 --> 0:28:35.240
<v Speaker 1>this as wen we end up eventually sort of transferring

0:28:35.240 --> 0:28:39.440
<v Speaker 1>out of this. As as as medical science advances, suddenly

0:28:39.480 --> 0:28:42.080
<v Speaker 1>the the idea becomes more about tissue. I mean, we're

0:28:42.120 --> 0:28:45.440
<v Speaker 1>keeping the basic idea of absorbing the essence of some

0:28:45.680 --> 0:28:50.720
<v Speaker 1>other more vital person's body intact, but we're just switching

0:28:50.760 --> 0:28:55.120
<v Speaker 1>from blood to well, maybe we need to implant some testicles. Yeah, yeah,

0:28:55.120 --> 0:28:58.240
<v Speaker 1>you see this. In the eighteen nineties and paris Um,

0:28:58.400 --> 0:29:03.760
<v Speaker 1>Charles Edward Brown Sequad was with a champion of testes

0:29:03.800 --> 0:29:09.880
<v Speaker 1>implantation um, Sergei Voronoff, would physically remove healthy testicles from

0:29:09.920 --> 0:29:14.719
<v Speaker 1>young animals and implant the glands into patients. So you know,

0:29:16.400 --> 0:29:18.680
<v Speaker 1>the thing is like that they're they're off base here,

0:29:18.760 --> 0:29:21.560
<v Speaker 1>but it's it's forecasting like real science to come and

0:29:21.640 --> 0:29:26.600
<v Speaker 1>real usable principles of of tissue and oregan transplants sometimes

0:29:26.640 --> 0:29:30.600
<v Speaker 1>between species. And of course blood transfusions are an essential

0:29:30.680 --> 0:29:33.960
<v Speaker 1>part of modern medical science. And it's not so much

0:29:34.000 --> 0:29:37.360
<v Speaker 1>that you absorb the blood of the young to gain

0:29:37.440 --> 0:29:40.640
<v Speaker 1>the power of the gladiator. But if you are ailing,

0:29:40.680 --> 0:29:43.440
<v Speaker 1>if if you have a blood deficiency you need blood

0:29:43.440 --> 0:29:45.480
<v Speaker 1>for some reason, of course you can get a blood

0:29:45.520 --> 0:29:47.800
<v Speaker 1>donation from someone. Yeah, I mean to fall back on

0:29:47.880 --> 0:29:51.560
<v Speaker 1>the biomechanical automobile example, it's like it's not so much

0:29:51.600 --> 0:29:54.240
<v Speaker 1>that you know, say what you will about old oil

0:29:54.280 --> 0:29:56.640
<v Speaker 1>and new oil. The machine needs oil to run, and

0:29:56.640 --> 0:29:59.720
<v Speaker 1>if the oil leaking out, you've got to add some more. Obviously,

0:30:00.120 --> 0:30:02.800
<v Speaker 1>it's the difference between you wouldn't try to steal the

0:30:02.880 --> 0:30:05.960
<v Speaker 1>oil from a sports car to gain the vitality of

0:30:06.000 --> 0:30:09.760
<v Speaker 1>the sports car. You just need oil from somewhere. It

0:30:09.840 --> 0:30:12.920
<v Speaker 1>can come from wherever, and so in this we end

0:30:12.960 --> 0:30:15.920
<v Speaker 1>up working back up to our modern age, to our

0:30:16.080 --> 0:30:18.560
<v Speaker 1>very modern age, as in studies that have come out

0:30:18.920 --> 0:30:22.680
<v Speaker 1>this year the last few years where we again see

0:30:22.720 --> 0:30:27.520
<v Speaker 1>this motif re emerge that you could take young blood,

0:30:27.600 --> 0:30:32.480
<v Speaker 1>specifically young blood into your older body and benefit from

0:30:32.520 --> 0:30:38.880
<v Speaker 1>it both physically and mentally. So we've talked about the mythology,

0:30:38.960 --> 0:30:44.040
<v Speaker 1>the magical thinking of absorbing the powerful essence of a strong, young, vigorous,

0:30:44.800 --> 0:30:48.480
<v Speaker 1>vital person by claiming their blood and making it your own.

0:30:48.960 --> 0:30:53.480
<v Speaker 1>But there is some actual science that runs bizarrely close

0:30:53.600 --> 0:30:57.560
<v Speaker 1>to this magical tradition. And this science has been in

0:30:57.680 --> 0:30:59.920
<v Speaker 1>development for a long time. I think it's it's been

0:31:00.080 --> 0:31:04.520
<v Speaker 1>sort of brewing for more than a century based on

0:31:04.640 --> 0:31:07.800
<v Speaker 1>some old techniques, but it's only in the past decade

0:31:07.920 --> 0:31:10.240
<v Speaker 1>or maybe a little more than the people have really

0:31:10.320 --> 0:31:14.440
<v Speaker 1>started to catch on to exactly how potent this type

0:31:14.480 --> 0:31:17.120
<v Speaker 1>of therapy could be. Yeah, really to the point now

0:31:17.160 --> 0:31:20.720
<v Speaker 1>where it's it's very promising. Yeah. Uh, And we don't

0:31:20.720 --> 0:31:22.800
<v Speaker 1>know yet what all of the implications are going to be.

0:31:22.840 --> 0:31:26.640
<v Speaker 1>But let's get into the details of why you would

0:31:26.680 --> 0:31:29.280
<v Speaker 1>take the blood of the young and give it to

0:31:29.320 --> 0:31:32.800
<v Speaker 1>the old in a medical context. Yeah. And one of

0:31:32.800 --> 0:31:35.360
<v Speaker 1>the a couple of big studies here that that that

0:31:35.720 --> 0:31:37.880
<v Speaker 1>we're drawing from. One of them was the two thousand,

0:31:37.920 --> 0:31:41.280
<v Speaker 1>fourteen Stanford University Medical Center study. UH. And and these

0:31:41.560 --> 0:31:45.480
<v Speaker 1>these efforts, of course involved prior studies and continuing studies.

0:31:45.720 --> 0:31:48.600
<v Speaker 1>This is very much a it's a network of findings. Yeah,

0:31:48.600 --> 0:31:51.200
<v Speaker 1>it's not just like a one off by any means. Yeah.

0:31:51.240 --> 0:31:54.280
<v Speaker 1>So it had already been before this one particular study,

0:31:54.280 --> 0:31:58.240
<v Speaker 1>had already been established that, uh, there was some indication

0:31:58.480 --> 0:32:02.400
<v Speaker 1>that some reins of the brains of old mice, when

0:32:02.480 --> 0:32:06.640
<v Speaker 1>given the blood of young mice, would produce more nerve cells.

0:32:06.720 --> 0:32:10.440
<v Speaker 1>And so obviously that's a good thing. But unfortunately the

0:32:10.440 --> 0:32:13.280
<v Speaker 1>reverse also held true. So when you gave young mice

0:32:13.720 --> 0:32:16.680
<v Speaker 1>exposure to the blood of old mice, they suffered for

0:32:16.720 --> 0:32:22.040
<v Speaker 1>it that they had decreased health outcomes, we might say. Right. So,

0:32:22.280 --> 0:32:25.720
<v Speaker 1>this time the researchers checked both for changes within nerve

0:32:25.840 --> 0:32:30.040
<v Speaker 1>circuits and individual nerve cells, uh, in order to to

0:32:30.120 --> 0:32:33.800
<v Speaker 1>demonstrate improvements in learning and memory. So first they examined

0:32:33.840 --> 0:32:38.080
<v Speaker 1>the pairs of mice whose circulatory systems had been surgically conjoined.

0:32:39.000 --> 0:32:41.080
<v Speaker 1>And this is the process we've been we've been doing

0:32:41.120 --> 0:32:46.400
<v Speaker 1>for a while, UM, a process known as parabiosis. Yeah.

0:32:46.480 --> 0:32:50.240
<v Speaker 1>We actually talked about this process on an episode of

0:32:50.280 --> 0:32:52.640
<v Speaker 1>Forward thinking that I recorded with my co hosts on

0:32:52.680 --> 0:32:59.000
<v Speaker 1>that show last year. But parabiosis is a very interesting, creepy,

0:32:59.400 --> 0:33:02.560
<v Speaker 1>weird procedure that that really gives a lot of people

0:33:02.600 --> 0:33:05.560
<v Speaker 1>the willies, but it has led to some very interesting

0:33:05.640 --> 0:33:08.320
<v Speaker 1>and promising medical outcomes, so I think it's really worth

0:33:08.360 --> 0:33:13.320
<v Speaker 1>talking about. So in this case, parabiosys, it comes from

0:33:13.400 --> 0:33:16.560
<v Speaker 1>the words meaning sort of beside life, so side to

0:33:16.600 --> 0:33:21.120
<v Speaker 1>side life essentially, and it refers to taking a patch

0:33:21.200 --> 0:33:25.080
<v Speaker 1>of skin off of two mice and then sowing the

0:33:25.120 --> 0:33:28.960
<v Speaker 1>mice together. Okay, so basically like hooking up the plumbing,

0:33:29.240 --> 0:33:33.520
<v Speaker 1>the circulatory plumbing. Yeah, so you're creating a common circulatory

0:33:33.640 --> 0:33:37.400
<v Speaker 1>system and causing the two mice to share a blood

0:33:37.440 --> 0:33:42.360
<v Speaker 1>stream and the blood becomes one common pool. They're parabiotic.

0:33:42.920 --> 0:33:46.240
<v Speaker 1>And the process collaboration, Yeah, exactly, they were working together,

0:33:46.800 --> 0:33:49.680
<v Speaker 1>they're they're getting closer. So this was a process that

0:33:49.760 --> 0:33:52.960
<v Speaker 1>was described by a French physiologist named Paul Barrett. It

0:33:53.120 --> 0:33:55.640
<v Speaker 1>spelled like bert I believe in French, that'd be Barrett.

0:33:55.760 --> 0:33:59.560
<v Speaker 1>I apologize if I'm wrong about that. In the sixties,

0:33:59.560 --> 0:34:03.840
<v Speaker 1>I think it, and then later in the nineteen thirties,

0:34:03.880 --> 0:34:07.120
<v Speaker 1>the process was improved upon by a pair of people

0:34:07.200 --> 0:34:12.040
<v Speaker 1>named Bunster and Meer. But essentially it entails taking two

0:34:12.080 --> 0:34:16.000
<v Speaker 1>mice side by side and attaching them at parallel elbows

0:34:16.000 --> 0:34:19.359
<v Speaker 1>and knees, and then sewing together an exposed patch of

0:34:19.400 --> 0:34:23.560
<v Speaker 1>skin along the sides, and of course then the natural

0:34:23.600 --> 0:34:27.960
<v Speaker 1>mammalian healing process kicks in the sides attached together, they

0:34:28.160 --> 0:34:31.440
<v Speaker 1>fuse the skin joins and the capillaries connect, and then

0:34:31.480 --> 0:34:34.160
<v Speaker 1>the mice can share this blood system and then apparently

0:34:34.200 --> 0:34:36.520
<v Speaker 1>after some length of time, the pair can be separated

0:34:36.560 --> 0:34:41.640
<v Speaker 1>again if necessary for the experiment. So that's the parabiasis.

0:34:41.680 --> 0:34:45.399
<v Speaker 1>But what is hetero chronic parabiasis, because that's what they

0:34:45.400 --> 0:34:50.279
<v Speaker 1>were really practicing here. Hetero chronic would mean mixed time right,

0:34:50.440 --> 0:34:54.239
<v Speaker 1>mixed time scales. So when you're creating parabiotic mice that

0:34:54.440 --> 0:34:57.960
<v Speaker 1>are hetero chronic, that means one old mouse and one

0:34:58.040 --> 0:35:02.160
<v Speaker 1>young mouse. And this is where the fund comes in,

0:35:02.360 --> 0:35:05.640
<v Speaker 1>because apparently when you join one old mouse and one

0:35:05.680 --> 0:35:10.160
<v Speaker 1>young mouse, you get startling results. In the nineteen fifties,

0:35:10.200 --> 0:35:13.440
<v Speaker 1>there was a guy at Cornell named Clive mackay, and

0:35:13.560 --> 0:35:19.759
<v Speaker 1>McKay performed experiments on parabiasis, essentially trying to learn what

0:35:19.840 --> 0:35:22.600
<v Speaker 1>he could about how to prolong lifespan. Can can you

0:35:22.680 --> 0:35:26.360
<v Speaker 1>take mammals and make them live longer by sharing blood

0:35:26.360 --> 0:35:29.120
<v Speaker 1>in this way? And what they found was that the

0:35:29.200 --> 0:35:33.200
<v Speaker 1>old mice who got paired up, who got sewn together

0:35:33.239 --> 0:35:37.360
<v Speaker 1>with a young mouse, showed rejuvenated cartilage, meaning that the

0:35:37.400 --> 0:35:42.080
<v Speaker 1>cartilage andist tissue in their body actually appeared younger. Uh.

0:35:42.120 --> 0:35:44.680
<v Speaker 1>And more recently, this line of research was picked up

0:35:44.719 --> 0:35:48.840
<v Speaker 1>on by a researcher named Thomas A. Rando who continue

0:35:49.000 --> 0:35:51.600
<v Speaker 1>continued this and published a study in Nature in two

0:35:51.640 --> 0:35:53.920
<v Speaker 1>thousand five. And this showed that if you took two

0:35:53.960 --> 0:35:56.160
<v Speaker 1>of these mice and you sewed them together, one old

0:35:56.200 --> 0:35:58.880
<v Speaker 1>mouse and one young mouse, and you left him that

0:35:58.920 --> 0:36:02.600
<v Speaker 1>way for five weeks, eventually the older mice showed improved

0:36:02.680 --> 0:36:07.680
<v Speaker 1>rates of muscle healing and liver cell regeneration. So that's

0:36:07.840 --> 0:36:11.799
<v Speaker 1>very interesting and promising. I read a Nature News piece

0:36:11.880 --> 0:36:14.320
<v Speaker 1>about this line of research that had a very funny

0:36:14.360 --> 0:36:17.600
<v Speaker 1>part where it said quote after the team published its results,

0:36:17.719 --> 0:36:21.399
<v Speaker 1>Rando's phone started ringing incessantly. Some of the calls were

0:36:21.440 --> 0:36:24.400
<v Speaker 1>from men's health magazines looking for ways to build muscle.

0:36:24.719 --> 0:36:28.240
<v Speaker 1>Others were from people fascinated by the idea of forestalling death.

0:36:28.520 --> 0:36:31.400
<v Speaker 1>They wanted to know whether young blood extended lifespan. So

0:36:31.480 --> 0:36:35.359
<v Speaker 1>already the vultures who don't want to die and don't

0:36:35.400 --> 0:36:39.239
<v Speaker 1>want to grow old are starting to pounce, said, I

0:36:39.320 --> 0:36:43.080
<v Speaker 1>find a young person without any limbs and just kind

0:36:43.080 --> 0:36:45.000
<v Speaker 1>of sew them out of my back like a living,

0:36:45.480 --> 0:36:50.879
<v Speaker 1>rejuvenating back back. You'd become master Blaster from from Thunderdome,

0:36:51.000 --> 0:36:54.240
<v Speaker 1>except it it would be you. I guess you'd be Blaster,

0:36:54.800 --> 0:36:57.680
<v Speaker 1>and then you'd have a master on your back who

0:36:57.800 --> 0:37:01.640
<v Speaker 1>is actually your blood slavey stitch on a millennial and

0:37:01.640 --> 0:37:04.680
<v Speaker 1>and hit the clubs right. But anyway, that's all of

0:37:04.719 --> 0:37:07.600
<v Speaker 1>the heterochronic parabiases, and that sort of brings us back

0:37:07.719 --> 0:37:10.759
<v Speaker 1>up into the research of the more recent years, including

0:37:10.760 --> 0:37:14.799
<v Speaker 1>this study. Yeah, and this study the hippocampus was really

0:37:14.880 --> 0:37:16.040
<v Speaker 1>craz key. You. Now, this is a part of the

0:37:16.080 --> 0:37:18.800
<v Speaker 1>brain brain that's critical for forming certain types of memories,

0:37:18.840 --> 0:37:25.600
<v Speaker 1>notably used in recollection and recognition of spatial patterns. Experience

0:37:25.719 --> 0:37:31.200
<v Speaker 1>physically alters it, and and various quote detrimental, anatomical and

0:37:31.280 --> 0:37:35.080
<v Speaker 1>functional changes occur there as an individual ages. So as

0:37:35.080 --> 0:37:37.680
<v Speaker 1>you get older, you're this part of your brain. I

0:37:37.719 --> 0:37:39.719
<v Speaker 1>think the brain in general, but especially this part of

0:37:39.719 --> 0:37:42.600
<v Speaker 1>your brain sees decline. Right. And it's also like one

0:37:42.600 --> 0:37:44.359
<v Speaker 1>of the examples is often thrown out, and I think

0:37:44.360 --> 0:37:45.799
<v Speaker 1>this has come up on the podcast before. You have

0:37:45.880 --> 0:37:50.160
<v Speaker 1>London cabbies who have who actually have have larger hippocampuses

0:37:50.840 --> 0:37:54.480
<v Speaker 1>due to the uh, you know, all the their knowledge,

0:37:54.480 --> 0:37:59.560
<v Speaker 1>their physical knowledge of the city. They not yeah, the knowledge. Um,

0:37:59.560 --> 0:38:04.080
<v Speaker 1>it's like or an order of warlocks, the kind of

0:38:04.080 --> 0:38:07.400
<v Speaker 1>warlocks of their own kind. Um. But in old mice

0:38:07.480 --> 0:38:10.880
<v Speaker 1>with new blood, they quote found consistent differences in a

0:38:10.960 --> 0:38:15.960
<v Speaker 1>number of biochemical, anatomical, and electrophysiological measures known to be

0:38:16.000 --> 0:38:20.680
<v Speaker 1>important to nerve cell circuits encoding of new experiences for

0:38:20.880 --> 0:38:25.480
<v Speaker 1>retention in the cerebral cortex. So essentially what's happening here

0:38:25.520 --> 0:38:28.799
<v Speaker 1>is the hippocamp i of older mice resemble that of

0:38:28.880 --> 0:38:33.480
<v Speaker 1>younger mice. They made greater amounts of various substances that

0:38:33.600 --> 0:38:37.240
<v Speaker 1>hippocampal cells are known to produce when learning is taking place,

0:38:37.280 --> 0:38:40.960
<v Speaker 1>So we see not only a tissue boost here, but

0:38:41.040 --> 0:38:45.240
<v Speaker 1>in actual mental boost like it's it's recharging the hippocampus,

0:38:45.280 --> 0:38:48.840
<v Speaker 1>recharging the mind of the young mouse. They also found

0:38:48.840 --> 0:38:52.680
<v Speaker 1>that hippocampal nerve cells from older members members of these uh,

0:38:52.960 --> 0:38:58.200
<v Speaker 1>these old young parabiotic pairs words, also showed an enhanced

0:38:58.239 --> 0:39:01.880
<v Speaker 1>ability to strengthen the connection between one nerve cell and another,

0:39:02.080 --> 0:39:05.240
<v Speaker 1>which again is essential to learning and forming new memories,

0:39:05.480 --> 0:39:09.719
<v Speaker 1>forging those internal pathways in the mind. And older mice

0:39:10.040 --> 0:39:12.440
<v Speaker 1>and fused with young blood also did better on food

0:39:12.520 --> 0:39:14.800
<v Speaker 1>hunting tests, such as one in particular where they would

0:39:14.920 --> 0:39:19.239
<v Speaker 1>have a food platform that's submerged in a water filled container. Okay,

0:39:19.320 --> 0:39:22.960
<v Speaker 1>so in this study they're not just looking at the

0:39:23.280 --> 0:39:26.400
<v Speaker 1>anatomical information. They're not just saying, hey, you know, what

0:39:26.560 --> 0:39:28.440
<v Speaker 1>is the number of cells we can find in this

0:39:28.480 --> 0:39:31.480
<v Speaker 1>part of the brain, but they're actually testing behavior how

0:39:31.520 --> 0:39:34.520
<v Speaker 1>it works in the field. Yea. Indeed, they also found

0:39:34.560 --> 0:39:36.960
<v Speaker 1>they performed better and freeze tests. Now, this is where

0:39:37.239 --> 0:39:40.239
<v Speaker 1>mice are trained to freeze and fear when plucked into

0:39:40.239 --> 0:39:44.080
<v Speaker 1>a particular environment. And while old mile mice usually perform

0:39:44.200 --> 0:39:47.440
<v Speaker 1>worse than the young, freezing for shorter periods of time,

0:39:47.600 --> 0:39:50.879
<v Speaker 1>betraying a lack of recognition. So, in other words, you've

0:39:50.920 --> 0:39:53.560
<v Speaker 1>been training to fear this environment, and if you the faster,

0:39:53.680 --> 0:39:56.480
<v Speaker 1>you recognize it and freeze and fear the longer you're frozen.

0:39:56.880 --> 0:40:00.479
<v Speaker 1>That shows that you're you're recalling it. But older mice

0:40:00.520 --> 0:40:03.759
<v Speaker 1>get desensitized to this. They don't recognize their conditions as

0:40:03.840 --> 0:40:09.880
<v Speaker 1>quickly correct. But when they have that that rejuvenating influx

0:40:09.880 --> 0:40:13.120
<v Speaker 1>of young blood, they perform better on the freeze test. Yeah,

0:40:13.440 --> 0:40:17.960
<v Speaker 1>but this kind of thing makes you wonder what is

0:40:18.000 --> 0:40:21.640
<v Speaker 1>it about the blood, because surely it's not it's not

0:40:21.719 --> 0:40:25.640
<v Speaker 1>a magical essence. It's not the gladiator strength being carried

0:40:25.640 --> 0:40:28.560
<v Speaker 1>through the magical properties of the blood. But it must

0:40:28.640 --> 0:40:31.760
<v Speaker 1>be some kind of material that's in the blood that's

0:40:31.840 --> 0:40:35.160
<v Speaker 1>doing this work of rejuvenation in the older mouse's brain.

0:40:35.640 --> 0:40:38.080
<v Speaker 1>So it would be interesting to see if we could

0:40:38.200 --> 0:40:41.560
<v Speaker 1>narrow down what it is in the blood that's causing

0:40:41.560 --> 0:40:44.520
<v Speaker 1>this change. And one of the interesting things that you

0:40:44.640 --> 0:40:47.200
<v Speaker 1>mentioned in a note about this is that apparently it

0:40:47.280 --> 0:40:51.960
<v Speaker 1>didn't work if you heat it up the blood plasma, right, Yeah,

0:40:51.960 --> 0:40:53.720
<v Speaker 1>So what apparently happens when you heat up the blood

0:40:54.000 --> 0:40:57.279
<v Speaker 1>is that it be natures or breaks apart key proteins.

0:40:57.320 --> 0:41:00.160
<v Speaker 1>And so there could be some blood borne protein means

0:41:00.160 --> 0:41:03.040
<v Speaker 1>that we've yet to identify and exploit that are are

0:41:03.160 --> 0:41:06.360
<v Speaker 1>central to this, uh, this this taking place. Yeah, and

0:41:06.400 --> 0:41:10.319
<v Speaker 1>then of course another study has I think identified what

0:41:10.400 --> 0:41:12.839
<v Speaker 1>they think are at least one of the key proteins.

0:41:13.040 --> 0:41:15.960
<v Speaker 1>That's right. A series of recent Harvard studies and these

0:41:16.000 --> 0:41:21.440
<v Speaker 1>are also using the stitch together old young mouse pairs

0:41:21.840 --> 0:41:26.560
<v Speaker 1>and uh. This research headed by stem cell researcher Amy Wagers,

0:41:26.800 --> 0:41:31.440
<v Speaker 1>isolated a specific protein from mouse blood growth differentiation factor

0:41:31.520 --> 0:41:34.799
<v Speaker 1>at eleven or g DF eleven, and this seems to

0:41:35.040 --> 0:41:37.960
<v Speaker 1>regulate stem cell activity and it's abundant in young mice,

0:41:38.000 --> 0:41:40.360
<v Speaker 1>but it's level drops at the animals a right, So

0:41:40.400 --> 0:41:42.279
<v Speaker 1>if you look at blood from a young mouse that's

0:41:42.320 --> 0:41:44.720
<v Speaker 1>got plenty of g DF eleven, you look at blood

0:41:44.719 --> 0:41:46.920
<v Speaker 1>from an old mouse, it has a lot less. So

0:41:47.000 --> 0:41:49.279
<v Speaker 1>this would seem to be something that you could be

0:41:49.360 --> 0:41:52.200
<v Speaker 1>re supplying to older mice by giving them the blood

0:41:52.200 --> 0:41:55.680
<v Speaker 1>plasma of younger mice. Yeah, And indeed they found that

0:41:55.760 --> 0:41:58.280
<v Speaker 1>injections of d d F eleven can reduce the thickening

0:41:58.320 --> 0:42:00.880
<v Speaker 1>of the heart to take with quickly comes with aging

0:42:00.920 --> 0:42:04.080
<v Speaker 1>in mice. They've also found that GDF eleven works nearly

0:42:04.120 --> 0:42:08.280
<v Speaker 1>as well as parabiosis in helping aging mouth mice recover

0:42:08.400 --> 0:42:11.760
<v Speaker 1>from muscle injuries, and it boost their performance on running

0:42:11.800 --> 0:42:16.000
<v Speaker 1>and grip strength tests. Grip strength huh yeah, grip strength

0:42:16.080 --> 0:42:20.520
<v Speaker 1>little mouse squeezies, I guess. Yeah, so you wouldn't just

0:42:20.600 --> 0:42:23.480
<v Speaker 1>be like a mentally rejuvenated mouse in a in a

0:42:23.520 --> 0:42:26.480
<v Speaker 1>weak decrepit body like it can actually give you some

0:42:26.480 --> 0:42:29.960
<v Speaker 1>some juice back to So along with the Easter Island

0:42:30.000 --> 0:42:36.239
<v Speaker 1>fungal agent reppams and also known as rapamune by fiser uh.

0:42:36.640 --> 0:42:41.080
<v Speaker 1>Along with that and caloric restriction. Uh, this is one

0:42:41.160 --> 0:42:46.240
<v Speaker 1>of only three intervention shown to reverse aging and multiple tissues.

0:42:46.520 --> 0:42:49.760
<v Speaker 1>So it's pretty pretty big. Yeah, but we do also

0:42:49.840 --> 0:42:53.440
<v Speaker 1>want to show caution here and say that it hasn't

0:42:53.520 --> 0:42:58.040
<v Speaker 1>yet been successfully demonstrated in humans, and that most of

0:42:58.080 --> 0:43:01.280
<v Speaker 1>the researchers who are trying to explain this to the public,

0:43:01.520 --> 0:43:05.920
<v Speaker 1>they always want to emphasize that this isn't necessarily like

0:43:06.000 --> 0:43:09.160
<v Speaker 1>a way to cheat death. It hasn't been shown to

0:43:09.320 --> 0:43:13.640
<v Speaker 1>prolonged life unnaturally. I mean it might if if the

0:43:13.760 --> 0:43:16.120
<v Speaker 1>data turns up, but it hasn't been shown to do

0:43:16.200 --> 0:43:21.040
<v Speaker 1>that yet. Instead, it's talking about showing renewed capacity in

0:43:21.160 --> 0:43:25.560
<v Speaker 1>certain tissues in older organisms. Yeah. So the more likely

0:43:26.280 --> 0:43:29.880
<v Speaker 1>use of this technology, this, uh, this procedure would be

0:43:29.920 --> 0:43:33.200
<v Speaker 1>for the treatment of Alzheimer's disease, the treatment of heart disease,

0:43:33.640 --> 0:43:39.279
<v Speaker 1>as opposed to some sort of futuristic slightly morbid longevity

0:43:39.320 --> 0:43:43.400
<v Speaker 1>treatment for the rich and privileged. Uh And and some

0:43:43.440 --> 0:43:45.080
<v Speaker 1>of the other caveats that are thrown out there is

0:43:45.680 --> 0:43:47.560
<v Speaker 1>the old mice that are used in many of these

0:43:47.560 --> 0:43:52.000
<v Speaker 1>experiments are essentially middle aged mice, and we're not sure

0:43:52.080 --> 0:43:54.080
<v Speaker 1>what the effects would be if they would be less

0:43:54.120 --> 0:43:58.680
<v Speaker 1>pronounced with truly old mice, or indeed with truly old humans.

0:43:59.280 --> 0:44:02.080
<v Speaker 1>But the cool thing is that since uh since blood

0:44:02.080 --> 0:44:06.480
<v Speaker 1>blood transfusions are routinely given to patients, trials like this

0:44:06.560 --> 0:44:10.319
<v Speaker 1>would not be would not have to have um authorization

0:44:10.320 --> 0:44:14.200
<v Speaker 1>from the US Food and Drug Administration. Uh So researchers

0:44:14.200 --> 0:44:16.640
<v Speaker 1>can test this out in humans, sooner read it than later. Now.

0:44:16.680 --> 0:44:18.640
<v Speaker 1>Of course, if they're testing this on humans, we're not

0:44:18.680 --> 0:44:22.480
<v Speaker 1>talking about parabiasis, not at all. They wouldn't be uh

0:44:22.640 --> 0:44:25.120
<v Speaker 1>so well, I mean, who knows. I really don't think

0:44:25.320 --> 0:44:28.440
<v Speaker 1>they would ever be thinking about sewing too humans together,

0:44:28.880 --> 0:44:31.960
<v Speaker 1>sewing you together with your grandpa to see if it

0:44:32.800 --> 0:44:35.960
<v Speaker 1>if it makes him healthier and you less healthy. And

0:44:36.000 --> 0:44:39.440
<v Speaker 1>another way that this would not be used is drinking blood,

0:44:39.480 --> 0:44:41.719
<v Speaker 1>because that's not what we're talking about. In fact, there

0:44:41.760 --> 0:44:44.000
<v Speaker 1>was a funny way I mentioned this in the Forward

0:44:44.000 --> 0:44:46.920
<v Speaker 1>Thinking podcast, but there was a New Scientist article interviewed

0:44:46.960 --> 0:44:49.000
<v Speaker 1>a guy named Tony whis Corey who was one of

0:44:49.000 --> 0:44:52.239
<v Speaker 1>the people working on this subject, and they got a

0:44:52.320 --> 0:44:54.719
<v Speaker 1>quote from him where he's like, certainly you can't drink

0:44:54.760 --> 0:44:59.880
<v Speaker 1>the blood, although obviously we haven't tried that experiment, so

0:45:00.239 --> 0:45:03.240
<v Speaker 1>I don't know if he was trying to say maybe

0:45:03.280 --> 0:45:04.960
<v Speaker 1>you could drink the blood that I don't think. So.

0:45:05.120 --> 0:45:06.800
<v Speaker 1>I don't think drinking the blood will do it. It

0:45:06.840 --> 0:45:11.000
<v Speaker 1>seems like it it's uh involving the direct transfusion of

0:45:11.040 --> 0:45:15.080
<v Speaker 1>the plasma, specially that g DF eleven, the growth growth

0:45:15.160 --> 0:45:19.239
<v Speaker 1>differentiation factor eleven, and then maybe some other elements in

0:45:19.360 --> 0:45:21.680
<v Speaker 1>the blood or the plasma. Yeah, I mean it has

0:45:21.719 --> 0:45:24.279
<v Speaker 1>to be circle tory to circulatory, not circular tory to

0:45:25.000 --> 0:45:28.760
<v Speaker 1>gastroid testinal. Yeah, that doesn't make sense. That's like cooking

0:45:28.840 --> 0:45:32.240
<v Speaker 1>your electricity up here to your planning system. But speaking

0:45:32.280 --> 0:45:36.799
<v Speaker 1>of Tony whist Corey, there is apparently under this particular

0:45:36.840 --> 0:45:41.880
<v Speaker 1>researcher and ongoing project that's studying the effect on human

0:45:41.920 --> 0:45:46.160
<v Speaker 1>Alzheimer's patients, and I think this is very interesting. The

0:45:46.520 --> 0:45:49.880
<v Speaker 1>last public update I found about this was a Nature

0:45:49.920 --> 0:45:54.640
<v Speaker 1>News article from January, so earlier this year, saying that

0:45:55.120 --> 0:45:59.759
<v Speaker 1>the experiment had started in September and it was a randomized,

0:46:00.040 --> 0:46:04.440
<v Speaker 1>cebo controlled, double blind trial, UH testing the safety and

0:46:04.440 --> 0:46:09.120
<v Speaker 1>efficacy of using young plasma to treat Alzheimer's disease. That

0:46:09.120 --> 0:46:10.600
<v Speaker 1>that was what they said, And then that they said

0:46:10.640 --> 0:46:13.879
<v Speaker 1>that six out of eighteen people who had originally been

0:46:13.920 --> 0:46:17.080
<v Speaker 1>planned for the experiment, who were all older than fifty,

0:46:17.200 --> 0:46:19.960
<v Speaker 1>had already started receiving the treatment, So they had already

0:46:20.000 --> 0:46:24.080
<v Speaker 1>been getting plasma that came from people who were below

0:46:24.120 --> 0:46:27.360
<v Speaker 1>the age of thirty. And so we haven't seen the

0:46:27.360 --> 0:46:29.120
<v Speaker 1>results of this yet, but I think it's going to

0:46:29.200 --> 0:46:35.560
<v Speaker 1>be really really interesting to see how this experiment turns out. Yeah,

0:46:35.560 --> 0:46:38.239
<v Speaker 1>I mean, when you sort of cut away all of

0:46:38.280 --> 0:46:42.240
<v Speaker 1>the mythic ghastliness that is built up with the idea

0:46:42.600 --> 0:46:46.560
<v Speaker 1>of reusing human blood or consuming it, or or the

0:46:46.640 --> 0:46:49.080
<v Speaker 1>old growing strong and the blood of the young, there's

0:46:49.120 --> 0:46:51.719
<v Speaker 1>a lot of there are a lot of wonderful possibilities

0:46:51.719 --> 0:46:56.000
<v Speaker 1>here for the treatment of conditions like Alzheimer's and heart disease. Yes, certainly.

0:46:56.320 --> 0:46:58.480
<v Speaker 1>Though then again, on the other side, there have been

0:46:58.520 --> 0:47:02.480
<v Speaker 1>other researchers who have been quick to warn that there

0:47:02.480 --> 0:47:05.000
<v Speaker 1>would be limits to even this type of procedure. Like

0:47:05.120 --> 0:47:08.399
<v Speaker 1>let's say that the results on the study come back

0:47:08.480 --> 0:47:13.000
<v Speaker 1>and they say, WHOA, Giving older people younger people's blood

0:47:13.000 --> 0:47:16.440
<v Speaker 1>has amazing effects even in humans, and it's been shown

0:47:16.480 --> 0:47:20.640
<v Speaker 1>in this double blind, placebo controlled trial. Uh, so we've

0:47:20.640 --> 0:47:24.360
<v Speaker 1>got a real, very important phenomenon on our hands. Even then,

0:47:24.440 --> 0:47:26.719
<v Speaker 1>you might want to show some caution because there was

0:47:26.760 --> 0:47:28.840
<v Speaker 1>a quote given to that Nature News piece I was

0:47:28.880 --> 0:47:33.200
<v Speaker 1>talking about from from that that same researcher that I

0:47:33.200 --> 0:47:37.359
<v Speaker 1>talked about earlier, Thomas A. Rando, and he said that

0:47:37.640 --> 0:47:40.279
<v Speaker 1>this could result in too much cell division. He said,

0:47:40.320 --> 0:47:44.640
<v Speaker 1>my suspicion is that chronic treatments with anything plasma drugs

0:47:44.680 --> 0:47:47.799
<v Speaker 1>that rejuvenate cells in old animals is going to lead

0:47:47.840 --> 0:47:51.160
<v Speaker 1>to an increase in cancer. Even if we learn how

0:47:51.200 --> 0:47:54.560
<v Speaker 1>to make cells young, it's something we'll want to do judiciously.

0:47:54.880 --> 0:47:56.319
<v Speaker 1>And that makes a lot of sense to me. So,

0:47:56.400 --> 0:47:58.640
<v Speaker 1>if you've got a problem, which is that there's not

0:47:58.800 --> 0:48:02.120
<v Speaker 1>enough cell division and cell growth in the body because

0:48:02.160 --> 0:48:05.480
<v Speaker 1>you've gotten old, if you want to fix it by

0:48:05.640 --> 0:48:08.960
<v Speaker 1>spurring lots of cell division and cell growth. That is

0:48:09.040 --> 0:48:13.720
<v Speaker 1>what leads to cancer. It's it's the balance of life.

0:48:13.760 --> 0:48:16.120
<v Speaker 1>I guess, yeah, But then again, I can easily imagine

0:48:16.120 --> 0:48:19.920
<v Speaker 1>it's an area where, again this is just speculating, where

0:48:20.320 --> 0:48:23.480
<v Speaker 1>an older individual has to make that choice. And I'm like, well,

0:48:24.000 --> 0:48:27.520
<v Speaker 1>I could certainly, I can certainly afford to hook this

0:48:27.600 --> 0:48:30.440
<v Speaker 1>young person up to meet some of their blood and

0:48:30.520 --> 0:48:33.000
<v Speaker 1>I'm gonna be a little sharper, my tissue is gonna improve,

0:48:33.040 --> 0:48:34.920
<v Speaker 1>I'm gonna feel a little younger, but I'm also going

0:48:34.960 --> 0:48:38.800
<v Speaker 1>to be more prone to cancer. You know, we're humans.

0:48:38.920 --> 0:48:42.839
<v Speaker 1>We're really suck at weighing a short term versus long term, right,

0:48:42.960 --> 0:48:44.919
<v Speaker 1>So I can I can see them saying, you know what,

0:48:45.040 --> 0:48:47.319
<v Speaker 1>I'm gonna feel young this week, and I'll worry about

0:48:47.360 --> 0:48:49.520
<v Speaker 1>cancer next week. I guess you could always go back

0:48:49.560 --> 0:48:52.360
<v Speaker 1>and forth, right, you could get maybe say, in the future,

0:48:52.400 --> 0:48:55.359
<v Speaker 1>we get really really good at treating cancer. So people

0:48:55.400 --> 0:48:58.400
<v Speaker 1>are taking way too many stem cells or blood transfusions

0:48:58.440 --> 0:49:02.560
<v Speaker 1>from the young get think this rejuvenated effect, but then

0:49:02.600 --> 0:49:05.719
<v Speaker 1>also getting cancer. And then they're just using our strongest

0:49:05.800 --> 0:49:08.799
<v Speaker 1>cancer fighting methods to fight off the cancer. And in

0:49:08.920 --> 0:49:12.600
<v Speaker 1>time to get some more rejuvenating juice from the young.

0:49:13.000 --> 0:49:16.879
<v Speaker 1>I think that these scenarios, as fun as they are

0:49:16.920 --> 0:49:19.319
<v Speaker 1>to imagine, somehow I don't think it's quite gonna work

0:49:19.360 --> 0:49:23.080
<v Speaker 1>out that way, because I I don't want this to

0:49:23.120 --> 0:49:25.719
<v Speaker 1>be the case. But what I suspect is that we

0:49:25.760 --> 0:49:28.320
<v Speaker 1>will see some result from this, but it will be

0:49:28.440 --> 0:49:32.120
<v Speaker 1>kind of modest, you know. But again, you combine that

0:49:32.400 --> 0:49:36.200
<v Speaker 1>with magical thinking, you combine that with the cebo effect,

0:49:36.320 --> 0:49:39.440
<v Speaker 1>you combine that with kind of a desperate willingness to

0:49:39.480 --> 0:49:44.200
<v Speaker 1>try something. I'm pretty confident you're gonna have some older,

0:49:44.280 --> 0:49:47.160
<v Speaker 1>well off individuals. She is going to make this happen

0:49:47.239 --> 0:49:51.000
<v Speaker 1>for himself or himself. Uh. One last thing I think

0:49:51.000 --> 0:49:55.240
<v Speaker 1>we should say again before the end of this episode is, unfortunately,

0:49:55.320 --> 0:49:58.319
<v Speaker 1>if you are reading anything about this, research that up

0:49:58.320 --> 0:50:00.960
<v Speaker 1>to this point has said that lud or plasma from

0:50:01.000 --> 0:50:04.600
<v Speaker 1>the young will make you live forever unnaturally extend your lifespan.

0:50:04.920 --> 0:50:07.200
<v Speaker 1>So far that is not true. That has not been

0:50:07.239 --> 0:50:12.360
<v Speaker 1>shown in any experiment that we could find evidence of,

0:50:12.920 --> 0:50:18.359
<v Speaker 1>so for now that ain't the case. Unfortunately. All Right,

0:50:18.400 --> 0:50:21.400
<v Speaker 1>So there you have it a little of the history,

0:50:21.880 --> 0:50:26.120
<v Speaker 1>the science and mythology of old people drinking young people's blood,

0:50:26.160 --> 0:50:29.160
<v Speaker 1>old people taking young blood into themselves, essentially the curative

0:50:29.320 --> 0:50:32.799
<v Speaker 1>properties of young blood. My main takeaway from this is

0:50:32.880 --> 0:50:36.520
<v Speaker 1>I want to drink whatever substance it is that will

0:50:37.120 --> 0:50:40.160
<v Speaker 1>help me look like Gary Oldman does at the beginning

0:50:40.200 --> 0:50:43.399
<v Speaker 1>of Francis Ford Coppola's Dracula. You mean the old bun

0:50:43.440 --> 0:50:46.680
<v Speaker 1>hair or the bun hair the young flashback out of

0:50:46.760 --> 0:50:49.200
<v Speaker 1>version with the with the cool armor. Oh well, well,

0:50:49.280 --> 0:50:51.840
<v Speaker 1>either way it would be great. But I mean, see,

0:50:51.920 --> 0:50:55.479
<v Speaker 1>if you're Gary Oldman's Dracula, you look great when you're

0:50:55.560 --> 0:50:58.040
<v Speaker 1>young and vital, and you look great as an old

0:50:58.080 --> 0:51:02.040
<v Speaker 1>decrepit bun hair. Either way, you're awesome. But also you're

0:51:02.120 --> 0:51:04.360
<v Speaker 1>kind of saying as an old person, I want to

0:51:04.400 --> 0:51:07.279
<v Speaker 1>look like I have that distinct look of a young

0:51:07.400 --> 0:51:10.120
<v Speaker 1>actor that's been made up to look like an old man,

0:51:10.239 --> 0:51:16.360
<v Speaker 1>sort of like the Prometheus version of what's his face? Right? Oh? Oh, no,

0:51:16.520 --> 0:51:20.120
<v Speaker 1>guy Pierce. And that's the worst makeup job I've ever

0:51:20.160 --> 0:51:23.719
<v Speaker 1>seen in film. No, Gary Oldman in Coppolis Dracula is

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<v Speaker 1>much better. Are not your ways? Our ways are not

0:51:29.120 --> 0:51:30.600
<v Speaker 1>your ways. This is a good place to leave off

0:51:30.640 --> 0:51:32.040
<v Speaker 1>with this one. So hey, if you want to check

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<v Speaker 1>out more episodes of Stuff to Blow Your Mind again,

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<v Speaker 1>head on over to stuff to Blow your Mind dot com.

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<v Speaker 1>That's the mother ship. That's where you'll find blog post galleries,

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<v Speaker 1>top ten with us, all the podcast episodes we've ever

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<v Speaker 1>social media accounts, and if you want to get in

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<v Speaker 1>touch with us with your thoughts about the consumption of

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<v Speaker 1>human blood, you can email us at blow the Mind

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<v Speaker 1>at how stuff works dot com for more on this

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<v Speaker 1>and thousands of other topics. Because House of Works dot

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<v Speaker 1>com h