WEBVTT - Ep 198 Sleep Part 1: Sleeping with one eye open

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<v Speaker 1>Hey everyone, it's Stephen Ray Morris. I'm here to tell

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<v Speaker 1>you a little bit about sleep paralysis and lucid dreaming

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<v Speaker 1>and where the two meet in the middle, which is me.

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<v Speaker 1>Sleeping has always been especially lately has been pretty difficult,

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<v Speaker 1>But for most of my life I've had pretty like

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<v Speaker 1>stressful dreams, to the point where I feel like sleep

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<v Speaker 1>isn't very RESTful for me. When I was younger, it

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<v Speaker 1>used to be really easy for me to fall asleep,

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<v Speaker 1>but then the actual dreams and things themselves wouldn't be

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<v Speaker 1>very RESTful. And that I think like a common theme

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<v Speaker 1>in my dreams is that I have to do a

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<v Speaker 1>task in a limited amount of time and there's an

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<v Speaker 1>obstacle getting in the way. And some of my favorite

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<v Speaker 1>examples of this are I am like a manager at

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<v Speaker 1>a brothel Christmas party, and I have to make sure

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<v Speaker 1>everybody gets their gifts, but all the gifts are unlabeled.

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<v Speaker 1>I have to catch a train, but I keep running

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<v Speaker 1>into people I haven't seen in a long time, so hey,

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<v Speaker 1>nice to see I Actually I got to catch that

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<v Speaker 1>train and then I run into somebody else. In college,

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<v Speaker 1>I started getting sleep paralysis. I still do from time

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<v Speaker 1>to time, but it was really bad where you know,

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<v Speaker 1>it's your brain is awake but your body is asleep.

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<v Speaker 1>So there's usually some sort of demon like nausicle dementor

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<v Speaker 1>style thing in the corner of the room, and it

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<v Speaker 1>just causes this intense fear and terror, and so I

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<v Speaker 1>usually wake up like everyone I've ever is whatever spent

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<v Speaker 1>the night with, have always had to deal with me

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<v Speaker 1>waking up and screaming from these forces. In college, I

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<v Speaker 1>met my roommate and my buddy Evan who's from the

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<v Speaker 1>Bay Area, and you know, we all watched Waking Life,

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<v Speaker 1>and in that movie they talk about lucy dreaming, which is,

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<v Speaker 1>you know, the ability to be aware that you're dreaming

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<v Speaker 1>and control your dreaming, etc.

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<v Speaker 2>Etc.

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<v Speaker 1>The two main things that I took away from it are,

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<v Speaker 1>you know, like AI, look at your hands or look

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<v Speaker 1>at clocks, because dreams can't represent either of the things

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<v Speaker 1>very well, so if you see them, that means you

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<v Speaker 1>know you're dreaming. So I started continuing these dreams where

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<v Speaker 1>just this intense fear as this dark figure is looming

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<v Speaker 1>in the corner, and I, after all this lucid dreaming

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<v Speaker 1>training or whatever, I started to like wriggle a little

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<v Speaker 1>bit you know, because I was so scared that I

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<v Speaker 1>was really trying to get away. And then one night,

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<v Speaker 1>as it got right over my bed was looming down

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<v Speaker 1>at me, I just remember this feeling of a you know,

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<v Speaker 1>like full like superhero movie like the strain, and I

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<v Speaker 1>reached my hand out and grabbed this sleep process demon

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<v Speaker 1>by the wrist, and then I woke up and I

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<v Speaker 1>didn't have sleep process again for a few years. I

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<v Speaker 1>still remember this so clearly like it was yesterday, even

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<v Speaker 1>though this was maybe, like I don't know, almost twenty

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<v Speaker 1>years ago. The sleep process still happens every once in

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<v Speaker 1>a while, but I think my lucid dreaming training still

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<v Speaker 1>serves me well occasionally, so I'm prepared basically anytime sleep

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<v Speaker 1>roll Stevens come at me.

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<v Speaker 3>Stephen, Stephen, I mean, first of all, terrifying, but also secondly,

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<v Speaker 3>what a joy to hear your voice.

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<v Speaker 4>Thank you so much for sharing your sleep and sleep

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<v Speaker 4>dreams sleep paralysis story with us.

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<v Speaker 3>It is so scary. I've had sleep proalyssis just a

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<v Speaker 3>few times in my life and I truly thought I

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<v Speaker 3>was dying.

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<v Speaker 4>I know, I don't know that I've ever had it,

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<v Speaker 4>but all of the stories that I hear, are like

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<v Speaker 4>really terrifying.

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<v Speaker 3>Yeah, yeah, so yeah, thank you, thank you.

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<v Speaker 5>Hi.

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<v Speaker 6>I'm Aaron Welsh and I'm Erin Allman.

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<v Speaker 3>Update and this is this podcast will kill you. Welcome

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<v Speaker 3>to the exactly Right Studio, Yes, where we will be

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<v Speaker 3>discussing in two episodes sleep. I'm excited for this very much.

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<v Speaker 3>So what are we going to be talking about. There's

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<v Speaker 3>a lot that we're going to cover and we will

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<v Speaker 3>not cover, so we are going to be typing. This

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<v Speaker 3>first episode, we're focusing on what sleep is essentially, like,

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<v Speaker 3>what does it entail, what is your brain doing a

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<v Speaker 3>little bit about why sleep is important or what we

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<v Speaker 3>think sleep is important for. I'm going to be talking

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<v Speaker 3>about sleep in animals a lot.

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<v Speaker 6>I'm really excited about it. I'm excited about too.

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<v Speaker 3>I did not know where it was going to go right.

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<v Speaker 3>And then next episode we're going to talk about some

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<v Speaker 3>of the consequences of sleep deprivation and also we're going

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<v Speaker 3>to be talking about the history of human sleep.

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<v Speaker 4>I'm really excited about that too. I think the second

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<v Speaker 4>episode is going to be a lot of interesting discussion

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<v Speaker 4>about how we think about sleep today.

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<v Speaker 3>I think so too. It I personally felt a lot

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<v Speaker 3>better about sleep.

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<v Speaker 4>Oh good, Yeah, that's great at the end of it,

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<v Speaker 4>happy to hear it, thank you, thank you hopefully everyone,

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<v Speaker 4>but not this week. No, this week you'll just learn

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<v Speaker 4>a lot about sleep.

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<v Speaker 3>Yeah, I'm excited, and you'll also have a really delicious.

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<v Speaker 4>Beverage go along with it, right, because it's quarantin any time.

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<v Speaker 3>It is in this case, it's plas breta time because alcohol,

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<v Speaker 3>spoiler alert, makes you sleep badly.

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<v Speaker 4>It's not good for your sleep, even though lots of

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<v Speaker 4>people use it as a sleep aid, far an anxiolytic.

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<v Speaker 6>Hmm, it's not good for either of those.

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<v Speaker 3>I mean, alcohol is not good for anything period, not

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<v Speaker 3>good for your body. There's no safe amount anyway.

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<v Speaker 6>Anyways, So.

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<v Speaker 4>Is is basically like a really nice version of a

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<v Speaker 4>Camma meal tea.

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<v Speaker 3>But what is it called erin it's called.

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<v Speaker 6>Pillar talk.

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<v Speaker 4>Yeah, the long pause of be trying to remember.

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<v Speaker 3>Well, because we had a few different options. There was

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<v Speaker 3>also bedtime stortory. Yeah, which would it's a great one. Yeah. Yeah,

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<v Speaker 3>it's a Cama meal tea plus ginger, honey syrup so good,

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<v Speaker 3>and a little bit of lemon in there.

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<v Speaker 6>Yeah. Kind of wish we had that sound.

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<v Speaker 3>Nice sounds good for your throat. Yeah.

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<v Speaker 4>Anyways, but you can make one and drink along with us.

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<v Speaker 4>We'll post the full recipe on our social media channels

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<v Speaker 4>for sure. Maybe on our website. Aaron walk us through

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<v Speaker 4>the website.

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<v Speaker 3>Oh, the website. Sorry for throwing are Yeah. The website

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<v Speaker 3>is a real joy to discover. You can find things

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<v Speaker 3>like transcripts. You can find things like the sources for

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<v Speaker 3>each and every one of our episodes. You can find

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<v Speaker 3>links to our bookshop dot org affiliate page, goodreads list, merch,

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<v Speaker 3>some pretty sweet merch. You can find links to music

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<v Speaker 3>by Bloodmobile, to contact us, form a first hand account form,

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<v Speaker 3>and probably some other things. There's an about us page too.

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<v Speaker 6>Sure it's not like four lines yep, it does.

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<v Speaker 3>Not contain a lot of information.

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<v Speaker 6>Oh so check that out.

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<v Speaker 4>Check it out, make sure you are rated, rate it,

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<v Speaker 4>make sure you are rape, make sure you have subscribed

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<v Speaker 4>and rate it.

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<v Speaker 6>Like to review and review the podcast.

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<v Speaker 4>We would appreciate that we're doing great. We're really killing

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<v Speaker 4>it today. Yeah, and if you are a fan of

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<v Speaker 4>watching things, we're on YouTube on the exactly.

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<v Speaker 3>Right so you can see some sweet pjs that we're wearing.

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<v Speaker 6>We're pretty excited about it.

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<v Speaker 3>I really like, I really like yours. It's very beatle juice.

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<v Speaker 6>Yours too, it is very beatle juice.

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<v Speaker 3>Thank you.

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<v Speaker 6>I love it.

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<v Speaker 4>We took a long time picking these out, everyone, so

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<v Speaker 4>we did. Okay, well with that.

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<v Speaker 3>Aaron, shall we take a break.

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<v Speaker 6>Business complete it, Business complete. Let's move on to learning

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<v Speaker 6>about sleep.

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<v Speaker 3>Love it?

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<v Speaker 2>Okay.

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<v Speaker 4>We all sleep, all of us humans, and Aarin, I

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<v Speaker 4>know that you are going to walk us through some

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<v Speaker 4>of the many different ways that animals sleep, which I'm

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<v Speaker 4>quite excited about, Like what does that.

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<v Speaker 6>Mean in animals?

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<v Speaker 3>What does it mean?

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<v Speaker 6>And there's such a variety there.

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<v Speaker 3>What does it mean to humans?

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<v Speaker 4>Well, let me tell you about it? And that's an

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<v Speaker 4>interesting question. It's because we all sleep. I think that

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<v Speaker 4>we all.

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<v Speaker 6>Know what it means to sleep.

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<v Speaker 4>One could even go so far as to say, much

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<v Speaker 4>like the Supreme Court Justice Potter Stewart said in nineteen

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<v Speaker 4>sixty four when trying to define hardcore pornography, I know

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<v Speaker 4>it when I see it. Yeah, yeah, we all know

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<v Speaker 4>what sleep is.

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<v Speaker 6>But what is sleep?

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<v Speaker 4>If we're trying to put like a label on it?

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<v Speaker 4>What are our brains doing when we sleep? And these

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<v Speaker 4>are the questions that I'm going to try and answer today,

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<v Speaker 4>But the biggest question is one that we cannot really

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<v Speaker 4>answer with what we know, and that is why, exactly

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<v Speaker 4>why do we sleep? We don't really know truly the

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<v Speaker 4>function of sleep, but we do have a lot of

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<v Speaker 4>thoughts and hypotheses which have various levels of support. So

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<v Speaker 4>we'll get into some of that as well, and then

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<v Speaker 4>next week, like we said, we'll talk more about what

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<v Speaker 4>makes good sleep good and what makes bad sleep bad?

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<v Speaker 3>It's so, and then what about like the quantities of

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<v Speaker 3>sleep and.

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<v Speaker 4>Allus we'll get into the architecture of sleep. You get

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<v Speaker 4>a dollar, okay, So what is sleep? If we define it? Sure,

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<v Speaker 4>a simplified definition is like a reduced state of voluntary

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<v Speaker 4>motor activity, so you're not mo you've got a decreased

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<v Speaker 4>response to stimulation. And in general, there's a stereotypic posture

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<v Speaker 4>associated with sleep. I know you'll talk more about that aeron,

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<v Speaker 4>but humans, the thought postures, I know, right, in humans

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<v Speaker 4>we lay down, right, Yeah, that's what we do for sleep.

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<v Speaker 4>And in contrast to other states that might be similar

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<v Speaker 4>to sleep, like say a coma, sleep is easily reversible, okay,

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<v Speaker 4>But in reality, in medicine, we have defined sleep based

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<v Speaker 4>on specific patterns of electrical activity in our brains e g.

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<v Speaker 6>Egs.

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<v Speaker 4>So let's get into it. We talked about egs or

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<v Speaker 4>electro encephalograms in our epilepsy episode.

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<v Speaker 3>Oh gosh, that was a long time ago.

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<v Speaker 4>It was a while back, and at that time I

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<v Speaker 4>was just like, I don't want to get into it, goodbye,

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<v Speaker 4>and we just didn't.

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<v Speaker 3>Talk to it someday today, today's the day.

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<v Speaker 4>So EEG's measure the electrical activity happening in our brains,

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<v Speaker 4>and the readouts of EEG's when you see them on

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<v Speaker 4>paper or on a computer, are these wave patterns, kind

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<v Speaker 4>of like if you've ever edited like a sound file,

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<v Speaker 4>you see these little wave patterns. They look very similar

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<v Speaker 4>to that. And waves, if anyone hasn't taken physics in

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<v Speaker 4>a long time, are measured by two main main measurements,

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<v Speaker 4>and that is amplitude.

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<v Speaker 6>Which is the height of the waves.

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<v Speaker 4>And frequency, which is the number of waves per second

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<v Speaker 4>or per.

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<v Speaker 6>Unit of time.

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<v Speaker 4>Right, Okay, So the higher the frequency, that means the

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<v Speaker 4>faster the waves, the closer together the waves are, and

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<v Speaker 4>we call that a high frequency, and then lower frequency

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<v Speaker 4>are slower waves. Okay, So longer wavelength, longer frequency. Okay,

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<v Speaker 4>Depending on what our brain is doing, our EG makes

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<v Speaker 4>a number of kind of predictable patterns, some of which

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<v Speaker 4>we only see when we're awake and some of which

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<v Speaker 4>we only really see when we're asleep. So when we're awake,

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<v Speaker 4>our EEG pattern shows these fast frequency, low amplitude waves.

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<v Speaker 3>Fast frequency low amplication, high frequency low altitude.

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<v Speaker 2>Yeah.

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<v Speaker 4>Yeah, so they're like close together waves and they're they're

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<v Speaker 4>not they're just little little baby waves. And the most

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<v Speaker 4>common two types of waveforms are called alpha waves and

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<v Speaker 4>beta waves.

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<v Speaker 6>There's a few others too.

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<v Speaker 4>Alpha rhythms are like calm, eyes closed, like meditation type

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<v Speaker 4>of vibes, and then beta waves are what we see

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<v Speaker 4>more with like activity of the brain.

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<v Speaker 3>Sorry, so we're talking about these are sleep, awake, sleep away.

0:12:29.840 --> 0:12:32.400
<v Speaker 6>This is what we're doing right now. We're probably beta waving.

0:12:33.160 --> 0:12:37.640
<v Speaker 3>We're definitely beta waving, not calm at all.

0:12:38.280 --> 0:12:43.360
<v Speaker 4>But during sleep, our EEG patterns change and we can

0:12:43.400 --> 0:12:47.480
<v Speaker 4>measure more than just the brain electricity. Actually, so when

0:12:47.520 --> 0:12:50.520
<v Speaker 4>we're measuring sleep, there's three main sets of measurements that

0:12:50.559 --> 0:12:53.880
<v Speaker 4>we're looking at. The EEG which is your brain electrical activity,

0:12:54.240 --> 0:12:58.840
<v Speaker 4>the e MG or electro milogram, which records activity in

0:12:58.840 --> 0:12:59.920
<v Speaker 4>our skeletal muscles.

0:13:00.040 --> 0:13:02.640
<v Speaker 6>Okay, and then the EOG.

0:13:02.320 --> 0:13:07.240
<v Speaker 4>Or electro oculogram, yes, which is measuring rapid eye movement, yes,

0:13:07.360 --> 0:13:11.199
<v Speaker 4>horizontal eye movement. And if we put all three of

0:13:11.240 --> 0:13:15.400
<v Speaker 4>these together, they result in what's called a polysomnogram or PSG.

0:13:16.200 --> 0:13:17.800
<v Speaker 4>So you can look up a picture of a PSG.

0:13:17.880 --> 0:13:20.600
<v Speaker 4>But it's like a lot of wires, a lot of Yeah,

0:13:20.640 --> 0:13:22.920
<v Speaker 4>and sometimes there's more if you're measuring like your pull

0:13:23.040 --> 0:13:24.520
<v Speaker 4>socks and your heart rate and things like that.

0:13:24.640 --> 0:13:29.040
<v Speaker 3>Okay. I've always wondered this about sleep study things. Yeah,

0:13:29.120 --> 0:13:30.800
<v Speaker 3>I feel like I would sleep terribly.

0:13:30.960 --> 0:13:34.080
<v Speaker 4>I know it's a valid concern. I don't have an

0:13:34.120 --> 0:13:34.600
<v Speaker 4>answer for.

0:13:34.600 --> 0:13:38.520
<v Speaker 3>It, Okay, So like how okay, another question, then, how

0:13:38.520 --> 0:13:42.480
<v Speaker 3>many nights will you sleep with wires, et cetera to

0:13:42.520 --> 0:13:44.960
<v Speaker 3>get like a good model of what your sleep is?

0:13:45.000 --> 0:13:48.840
<v Speaker 6>Like, that's a great question. I don't know a lot

0:13:48.840 --> 0:13:51.160
<v Speaker 6>of a lot of times.

0:13:51.360 --> 0:13:53.880
<v Speaker 4>It might just be one night, just one night, yeah,

0:13:53.920 --> 0:13:56.240
<v Speaker 4>but it totally depends on what the scenario is, what

0:13:56.280 --> 0:13:58.760
<v Speaker 4>the study is, and like what information they get from

0:13:58.760 --> 0:13:59.880
<v Speaker 4>that kind of a thing.

0:14:00.120 --> 0:14:02.480
<v Speaker 3>I find that so interesting because I feel like sleep

0:14:02.559 --> 0:14:03.480
<v Speaker 3>is so variable.

0:14:03.559 --> 0:14:08.040
<v Speaker 4>Oh, it's so variable, Aaron, It can totally be so variable. Yeah,

0:14:08.080 --> 0:14:10.319
<v Speaker 4>So I don't have a great answer to that, Okay, yeah, yeah,

0:14:10.440 --> 0:14:12.240
<v Speaker 4>totally totally depends on the study and what they're doing,

0:14:12.240 --> 0:14:15.880
<v Speaker 4>what they're looking for. But based on these PSG readings,

0:14:15.920 --> 0:14:17.679
<v Speaker 4>what we've done over the years in studying many people

0:14:17.720 --> 0:14:20.680
<v Speaker 4>for longer periods and in the lab et cetera, we

0:14:20.880 --> 0:14:26.600
<v Speaker 4>now can divide sleep into two main phases. There's REM

0:14:26.720 --> 0:14:30.520
<v Speaker 4>sleep just two okay, well, two main divisions. Y, there's

0:14:30.520 --> 0:14:33.560
<v Speaker 4>faces within these, but the two main divisions are REM

0:14:33.640 --> 0:14:37.800
<v Speaker 4>or rapid eye movement sleep and non REM or non rapid.

0:14:37.520 --> 0:14:38.200
<v Speaker 6>Eye movement sleep.

0:14:38.280 --> 0:14:38.760
<v Speaker 3>Yeah.

0:14:38.880 --> 0:14:43.080
<v Speaker 4>Within non REM sleep, there are three different phases sometimes four.

0:14:43.600 --> 0:14:45.960
<v Speaker 4>Sometimes Stage three and four are separated.

0:14:46.080 --> 0:14:48.440
<v Speaker 3>And this is just depending on classification, not like.

0:14:48.520 --> 0:14:52.200
<v Speaker 4>Yeah, the older the older literature kind of says there's

0:14:52.240 --> 0:14:56.800
<v Speaker 4>four stages of non REM and the newer literature is like, realistically,

0:14:56.840 --> 0:14:58.840
<v Speaker 4>deep sleep is all deep sleep. We'll just call it

0:14:58.880 --> 0:15:02.000
<v Speaker 4>phase three. Oh interesting, So anyways, it doesn't really matter.

0:15:02.280 --> 0:15:04.840
<v Speaker 4>But let's walk through what a night of sleep looks

0:15:04.920 --> 0:15:11.200
<v Speaker 4>like together. Because we fall asleep in relatively predictable patterns

0:15:11.280 --> 0:15:14.200
<v Speaker 4>and as we fall asleep, our brain waves kind of

0:15:14.200 --> 0:15:17.840
<v Speaker 4>get slower and slower as we go. So, like I

0:15:17.840 --> 0:15:20.200
<v Speaker 4>said before, as we're awake and relaxed, our brain is

0:15:20.200 --> 0:15:24.480
<v Speaker 4>in this alpha wave pattern, which is low amplitude, relatively

0:15:24.560 --> 0:15:31.080
<v Speaker 4>high frequency waves. Then as we fall into stage one sleep,

0:15:31.120 --> 0:15:33.600
<v Speaker 4>which is one of the stages of non rem we

0:15:33.680 --> 0:15:37.400
<v Speaker 4>call it kind of drowsiness, we'll slip into this pattern

0:15:37.480 --> 0:15:45.000
<v Speaker 4>called theta waves, which is slightly lower frequency, still low amplitude.

0:15:45.520 --> 0:15:47.360
<v Speaker 3>Slightly lower frequency.

0:15:46.920 --> 0:15:51.119
<v Speaker 4>So a little longer wavelengths and a little longer frequency

0:15:51.840 --> 0:15:56.640
<v Speaker 4>than the alpha waves, but still low amplitude.

0:15:56.800 --> 0:15:58.920
<v Speaker 3>Okay, little down there.

0:15:59.480 --> 0:16:02.320
<v Speaker 4>Muscle eyes, you might have these little like twitches or

0:16:02.400 --> 0:16:05.480
<v Speaker 4>muscle jerks as we all know why, I don't know.

0:16:08.600 --> 0:16:11.720
<v Speaker 4>And then stage two is when you start to truly

0:16:11.800 --> 0:16:15.360
<v Speaker 4>fall asleep. This is when conscious awareness is gone. Your

0:16:15.440 --> 0:16:19.800
<v Speaker 4>muscle activity decreases substantially, and your brain waves will continue

0:16:19.840 --> 0:16:21.840
<v Speaker 4>in this theta wave pattern. But then we see them

0:16:21.880 --> 0:16:26.320
<v Speaker 4>punctuated by these really weird little bursts of activity, these

0:16:26.560 --> 0:16:30.440
<v Speaker 4>short little bursts of super high frequency events that are

0:16:30.480 --> 0:16:34.560
<v Speaker 4>called spindles, followed by what's called a K complex, which

0:16:34.600 --> 0:16:39.720
<v Speaker 4>is this very it's a low frequency, high amplitude just

0:16:39.760 --> 0:16:46.080
<v Speaker 4>like one two high amplitude so like wide and tall, weird?

0:16:46.640 --> 0:16:49.240
<v Speaker 4>Just what and that's a k complex okay, And that's

0:16:49.280 --> 0:16:52.240
<v Speaker 4>like stage two. So we see this mostly like slightly

0:16:52.360 --> 0:16:55.360
<v Speaker 4>chiller pattern, then awake and then little bursts of.

0:16:56.920 --> 0:16:59.160
<v Speaker 3>Ye yeah, like a heart almost like a heartbeat kind

0:16:59.200 --> 0:17:00.200
<v Speaker 3>of yeah.

0:17:00.840 --> 0:17:06.560
<v Speaker 4>Sure, we'll say sure, yeah. And then after stage two

0:17:06.720 --> 0:17:09.680
<v Speaker 4>we fall into deep sleep or slow wave sleep.

0:17:09.760 --> 0:17:13.480
<v Speaker 3>Stage three, I'm guessing frequency goes down, yeah, tell me

0:17:13.520 --> 0:17:14.480
<v Speaker 3>about amplitude.

0:17:14.600 --> 0:17:18.639
<v Speaker 4>Amplitude goes up. So we see this high amplitude low

0:17:18.760 --> 0:17:22.840
<v Speaker 4>low frequency slow waves that we call delta waves.

0:17:23.640 --> 0:17:27.480
<v Speaker 3>What is what does it mean to have high amplitude?

0:17:27.560 --> 0:17:27.760
<v Speaker 5>You know?

0:17:28.080 --> 0:17:28.679
<v Speaker 3>Yeah?

0:17:29.040 --> 0:17:33.240
<v Speaker 4>So the waves are created essentially by this like activity

0:17:33.320 --> 0:17:37.119
<v Speaker 4>of our neurotransmitters happening all at once, and so really

0:17:37.160 --> 0:17:40.600
<v Speaker 4>it's that the activity patterns in various parts of our

0:17:40.640 --> 0:17:44.960
<v Speaker 4>brain have slowed down, essentially, is what we're seeing.

0:17:44.680 --> 0:17:47.040
<v Speaker 3>For the frequency, right, And what about the amplitude.

0:17:47.080 --> 0:17:49.920
<v Speaker 4>I don't know the answer, amplitude, Yeah, I really don't.

0:17:50.400 --> 0:17:53.040
<v Speaker 4>This is why I'm like not an EEG expert, and

0:17:53.080 --> 0:17:54.679
<v Speaker 4>maybe someone who is can let us know.

0:17:55.480 --> 0:17:56.000
<v Speaker 6>I don't.

0:17:57.520 --> 0:18:00.879
<v Speaker 4>But that is deep sleep or slow wave sleep so

0:18:00.920 --> 0:18:03.840
<v Speaker 4>we'll stay in that sleep for a period of time,

0:18:04.240 --> 0:18:07.720
<v Speaker 4>don't know how long, depends on you, and then we

0:18:07.880 --> 0:18:10.520
<v Speaker 4>pop up quickly to stage two. We pass through that

0:18:10.520 --> 0:18:14.199
<v Speaker 4>pretty quickly, and then we enter our first rem sleep

0:18:14.440 --> 0:18:14.960
<v Speaker 4>of the night.

0:18:15.240 --> 0:18:19.520
<v Speaker 3>So deep sleep is one. That's stage that's the first

0:18:19.560 --> 0:18:20.479
<v Speaker 3>thing that we encounter.

0:18:20.680 --> 0:18:24.160
<v Speaker 4>No, we go we go stage one, Stage two, Stage three,

0:18:24.240 --> 0:18:25.080
<v Speaker 4>which is deep sleep.

0:18:25.160 --> 0:18:26.320
<v Speaker 6>Oh, okay, we'll stay.

0:18:26.119 --> 0:18:28.880
<v Speaker 4>There for a little while, and then we'll go stage two.

0:18:29.080 --> 0:18:33.480
<v Speaker 4>Rem got it, okay. And in contrast to all these

0:18:33.520 --> 0:18:38.879
<v Speaker 4>other sleep patterns where waves are getting longer and in

0:18:39.080 --> 0:18:42.480
<v Speaker 4>REM sleep, your brain EEG pattern looks like you're awake.

0:18:43.040 --> 0:18:45.520
<v Speaker 4>It is an awake beta wave, so not even like

0:18:45.520 --> 0:18:48.000
<v Speaker 4>a calm alpha wave pattern. It's like a beta wave.

0:18:48.520 --> 0:18:50.960
<v Speaker 4>This is a type of pattern.

0:18:50.920 --> 0:18:54.360
<v Speaker 3>Like we're recording an episode in our sleep. Our sleep.

0:18:55.960 --> 0:18:58.800
<v Speaker 4>And REM sleep is also characterized by like a more

0:18:58.880 --> 0:19:01.760
<v Speaker 4>awake type of physio. Our blood pressure is higher, our

0:19:01.800 --> 0:19:04.760
<v Speaker 4>heart rate is higher, our respiratory rate is higher compared

0:19:04.800 --> 0:19:05.840
<v Speaker 4>to non REM sleep.

0:19:06.119 --> 0:19:07.920
<v Speaker 3>What about our temperature our body temp.

0:19:08.200 --> 0:19:09.960
<v Speaker 4>Oh, that's a good question. I think our body temperature

0:19:09.960 --> 0:19:12.200
<v Speaker 4>goes up as well too. Okay, still probably not quite

0:19:12.240 --> 0:19:14.360
<v Speaker 4>as high as it is because in general our body

0:19:14.359 --> 0:19:16.199
<v Speaker 4>temperature falls with sleep, but it's going to go up

0:19:16.200 --> 0:19:21.280
<v Speaker 4>compared to deep sleep. Okay, however, we have two weird

0:19:21.320 --> 0:19:23.640
<v Speaker 4>things happening in REM sleep that we do not see

0:19:23.640 --> 0:19:27.000
<v Speaker 4>when we're awake, and that is these rapid horizontal eye

0:19:27.040 --> 0:19:32.680
<v Speaker 4>movements Yep, that happen, and our skeletal muscle activity is

0:19:32.760 --> 0:19:33.840
<v Speaker 4>essentially atonic.

0:19:34.040 --> 0:19:35.440
<v Speaker 6>We really do not move.

0:19:35.840 --> 0:19:38.000
<v Speaker 3>We don't so we move even less than we do

0:19:38.119 --> 0:19:39.920
<v Speaker 3>in our falling asleep twitchy.

0:19:39.800 --> 0:19:43.320
<v Speaker 4>Correct, Yeah, you might still have occasional muscle twitches, but

0:19:43.400 --> 0:19:46.400
<v Speaker 4>in general, your skeletal muscles, so like arms and legs,

0:19:46.480 --> 0:19:47.920
<v Speaker 4>are not really moving.

0:19:48.480 --> 0:19:50.960
<v Speaker 3>I know that this is all foundational, so that someday

0:19:51.000 --> 0:19:53.440
<v Speaker 3>we will talk about sleep disorders in more details. Yeah,

0:19:53.480 --> 0:19:55.960
<v Speaker 3>but it is making me want to ask one thousand

0:19:56.000 --> 0:20:01.000
<v Speaker 3>and one question. Yeah about like what happens when sleepwalking anyway?

0:20:01.040 --> 0:20:03.520
<v Speaker 4>We yeah, yeah, sleepwalking is something you'd see more in

0:20:03.600 --> 0:20:06.080
<v Speaker 4>the deep sleep. In the deep sleep, right, because you're

0:20:06.119 --> 0:20:09.240
<v Speaker 4>again in REM sleep, your muscles are not moving, right,

0:20:09.359 --> 0:20:12.480
<v Speaker 4>so in REM sleep we can see things like sleep paralysis.

0:20:12.480 --> 0:20:13.440
<v Speaker 4>We think that that's like.

0:20:13.680 --> 0:20:16.240
<v Speaker 3>You're yeah, because you can't move, you're.

0:20:16.040 --> 0:20:21.399
<v Speaker 4>Having basically rem sleep muscle activity, but with an awake

0:20:21.480 --> 0:20:23.719
<v Speaker 4>brain where you actually do wake up. And that's what

0:20:23.760 --> 0:20:25.639
<v Speaker 4>we think is happening in sleep paralysis.

0:20:26.760 --> 0:20:28.040
<v Speaker 6>And that's all I'm going to talk about when it

0:20:28.080 --> 0:20:28.600
<v Speaker 6>comes to dreams.

0:20:28.680 --> 0:20:29.320
<v Speaker 3>Yeah, FYI.

0:20:30.640 --> 0:20:33.560
<v Speaker 4>So in a night of sleep, we cycle through both

0:20:33.600 --> 0:20:36.920
<v Speaker 4>non REM and REM sleep in a pretty typical pattern.

0:20:37.040 --> 0:20:40.000
<v Speaker 4>We go from stage one to two to three that

0:20:40.080 --> 0:20:42.840
<v Speaker 4>quick pickstop at two and then back up to REM

0:20:43.240 --> 0:20:47.400
<v Speaker 4>and that once we end that REM cycle is considered

0:20:47.480 --> 0:20:51.040
<v Speaker 4>one sleep cycle. And in adults, a sleep cycle lasts

0:20:51.040 --> 0:20:54.200
<v Speaker 4>between like ninety and one hundred or so minutes. Okay,

0:20:54.680 --> 0:20:57.359
<v Speaker 4>so depending on how long you sleep at night, we

0:20:57.440 --> 0:21:00.440
<v Speaker 4>might go through like four or five or more of

0:21:00.480 --> 0:21:01.440
<v Speaker 4>these cycles.

0:21:01.920 --> 0:21:03.919
<v Speaker 3>Okay, I have a question about give it to me

0:21:04.760 --> 0:21:09.159
<v Speaker 3>the REM like deep sleep. So I remember reading that

0:21:09.200 --> 0:21:13.920
<v Speaker 3>deep sleep happens early on in the night. Correct, yes, why,

0:21:14.960 --> 0:21:16.960
<v Speaker 3>and but REM sleep happens throughout.

0:21:17.160 --> 0:21:19.960
<v Speaker 4>We tend to have more deep sleep early in the night,

0:21:20.560 --> 0:21:23.159
<v Speaker 4>and then like shorter periods of REM sleep earlier in

0:21:23.200 --> 0:21:25.600
<v Speaker 4>the night and longer periods of REM sleep later in

0:21:25.600 --> 0:21:28.919
<v Speaker 4>the night, and then it's possible that you might not

0:21:29.160 --> 0:21:31.440
<v Speaker 4>like later in the night, drop all the way down

0:21:31.440 --> 0:21:35.679
<v Speaker 4>to that deep sleep like stage three n REM, you

0:21:35.760 --> 0:21:38.000
<v Speaker 4>might maybe just go to stage two then up to

0:21:38.080 --> 0:21:40.760
<v Speaker 4>REM a couple of times in your later sleep cycles.

0:21:42.200 --> 0:21:43.080
<v Speaker 6>Yes, that is true.

0:21:43.119 --> 0:21:47.159
<v Speaker 4>Why I don't know Erin It's also really interesting because

0:21:47.200 --> 0:21:49.119
<v Speaker 4>like the amount of deep sleep that you get also

0:21:49.200 --> 0:21:52.880
<v Speaker 4>correlates to how much sleep you got, say, the night before.

0:21:53.520 --> 0:21:55.920
<v Speaker 4>So if you are sleep deprived and you're running off

0:21:55.960 --> 0:21:59.200
<v Speaker 4>of like sleep debt as they sometimes call it, then

0:21:59.280 --> 0:22:01.879
<v Speaker 4>your next night of sleep will likely have more of

0:22:01.920 --> 0:22:04.159
<v Speaker 4>that slow wave or deep sleep compared to the night

0:22:04.200 --> 0:22:05.879
<v Speaker 4>before recovery sleep.

0:22:06.040 --> 0:22:09.320
<v Speaker 3>Kind of, So the in terms of the breakdown of

0:22:09.520 --> 0:22:12.879
<v Speaker 3>like I'm the sleep cycle, not even like the number,

0:22:12.920 --> 0:22:16.280
<v Speaker 3>but just the proportion overall. I'm getting ahead of things

0:22:16.320 --> 0:22:20.960
<v Speaker 3>you are. Yeah, but I'm what proportion of sleep quote

0:22:21.000 --> 0:22:25.280
<v Speaker 3>unquote should be REM, should be deep sleep, should be whatever?

0:22:25.440 --> 0:22:25.960
<v Speaker 3>Stage two?

0:22:26.080 --> 0:22:28.439
<v Speaker 4>Yeah, it depends on your age and your stage of

0:22:28.480 --> 0:22:30.600
<v Speaker 4>life and things like that. So babies have like a

0:22:30.640 --> 0:22:33.360
<v Speaker 4>lot more REM sleep than adults. They've got like over

0:22:33.440 --> 0:22:36.720
<v Speaker 4>forty percent REM sleep. Adults it's usually twenty to thirty

0:22:36.760 --> 0:22:41.040
<v Speaker 4>percent is considered typical, and then twenty I think it's

0:22:41.040 --> 0:22:42.840
<v Speaker 4>like fifteen to twenty percent. It's in my notes from

0:22:42.840 --> 0:22:45.720
<v Speaker 4>next episodes, so we'll get more into it. But yeah,

0:22:45.760 --> 0:22:47.960
<v Speaker 4>it's usually like fifteen to twenty percent or so. Is

0:22:48.000 --> 0:22:50.800
<v Speaker 4>deep sleep oh or should be deep sleep typical deep?

0:22:50.920 --> 0:22:52.160
<v Speaker 3>Oh my gosh, I mean.

0:22:52.000 --> 0:22:54.440
<v Speaker 4>And then the rest is that like stage two type

0:22:54.440 --> 0:22:57.880
<v Speaker 4>of sleep stage yeah, or bouncing between you know, stage

0:22:58.040 --> 0:22:59.000
<v Speaker 4>one and stage two.

0:22:58.920 --> 0:23:00.560
<v Speaker 3>Sort of like that, which is not I mean I

0:23:00.600 --> 0:23:02.600
<v Speaker 3>feel like deep sleep and RAM are like the stars

0:23:02.600 --> 0:23:03.119
<v Speaker 3>of the show.

0:23:03.320 --> 0:23:06.000
<v Speaker 4>Yeah, they get the crag even though you're not the

0:23:06.040 --> 0:23:07.080
<v Speaker 4>majority of your.

0:23:06.920 --> 0:23:08.920
<v Speaker 3>Sleep, right, which is also important.

0:23:09.040 --> 0:23:12.040
<v Speaker 4>It is it is, Yeah, but that is like how

0:23:12.119 --> 0:23:15.919
<v Speaker 4>your sleep cycle goes throughout the night, and it is

0:23:15.960 --> 0:23:17.960
<v Speaker 4>going to depend how much time you spend in each

0:23:18.000 --> 0:23:20.560
<v Speaker 4>one of these from night to night, from person to person,

0:23:20.760 --> 0:23:24.400
<v Speaker 4>And anybody who has one of those rings or one

0:23:24.400 --> 0:23:29.040
<v Speaker 4>of those watches that's monitoring your sleep knows that these

0:23:29.080 --> 0:23:29.760
<v Speaker 4>things are going to.

0:23:29.840 --> 0:23:30.520
<v Speaker 6>Very night tonight.

0:23:30.800 --> 0:23:34.159
<v Speaker 4>Yeah, So, speaking of which, I just wanted to good.

0:23:34.600 --> 0:23:36.320
<v Speaker 3>Yeah, I'm glad you're talking about I just wanted.

0:23:36.160 --> 0:23:38.760
<v Speaker 4>To talk about these real quick because there is so

0:23:39.040 --> 0:23:42.160
<v Speaker 4>much out there right now that's like you need one

0:23:42.200 --> 0:23:44.119
<v Speaker 4>of these rings to monitor your sleep, and you need

0:23:44.160 --> 0:23:46.600
<v Speaker 4>to be monitoring your sleep, and these are this one

0:23:46.640 --> 0:23:49.200
<v Speaker 4>is the best one to be monitoring it, et cetera.

0:23:51.800 --> 0:23:55.959
<v Speaker 4>I found a paper that was not sponsored by the

0:23:56.000 --> 0:23:58.919
<v Speaker 4>manufacturer of any of these devices, just the one.

0:23:59.080 --> 0:23:59.360
<v Speaker 3>Just one.

0:23:59.400 --> 0:24:00.359
<v Speaker 6>There's a lot of.

0:24:00.119 --> 0:24:02.320
<v Speaker 4>Papers that are sponsored by that were like funded by

0:24:02.320 --> 0:24:04.600
<v Speaker 4>the manufacturing of these things, who will say like, oh,

0:24:04.640 --> 0:24:06.840
<v Speaker 4>these are like seventy five to eighty percent accurate compared

0:24:06.840 --> 0:24:10.040
<v Speaker 4>to PSGs, Like these are super super accurate. So I

0:24:10.080 --> 0:24:13.320
<v Speaker 4>found one paper that was comparing a number of different rings.

0:24:13.359 --> 0:24:16.840
<v Speaker 4>It wasn't as much looking at the watches that was

0:24:16.880 --> 0:24:19.320
<v Speaker 4>trying to figure out could these be as good as

0:24:19.640 --> 0:24:22.560
<v Speaker 4>PSGs that we do in clinic, which is really important

0:24:22.720 --> 0:24:25.720
<v Speaker 4>because especially to diagnose a lot of sleep disorders, like.

0:24:25.680 --> 0:24:28.359
<v Speaker 3>You do need this data, and it's like accessibility and

0:24:28.640 --> 0:24:29.960
<v Speaker 3>these and all of these things.

0:24:30.040 --> 0:24:32.040
<v Speaker 4>Right, So it's like if we could use these clinically,

0:24:32.080 --> 0:24:33.640
<v Speaker 4>that would be really awesome.

0:24:33.400 --> 0:24:34.919
<v Speaker 3>Right, And then you're not having to wear all of

0:24:34.960 --> 0:24:37.000
<v Speaker 3>these tubes that make you sleep poorly and then you're

0:24:37.000 --> 0:24:39.320
<v Speaker 3>like you're a terrible sleeper. You need all these things.

0:24:39.320 --> 0:24:40.199
<v Speaker 3>And it's like I was just.

0:24:40.359 --> 0:24:44.600
<v Speaker 4>Had well and like the ability to be able to

0:24:44.600 --> 0:24:47.159
<v Speaker 4>do it at home is so yeah. So there's so

0:24:47.280 --> 0:24:49.280
<v Speaker 4>much that would be great if these things were really great,

0:24:49.480 --> 0:24:51.359
<v Speaker 4>The problem is that they're not.

0:24:52.760 --> 0:24:55.880
<v Speaker 6>And it's not that they're not decent.

0:24:57.119 --> 0:25:00.800
<v Speaker 4>But I will quote here because I think that this

0:25:00.880 --> 0:25:04.680
<v Speaker 4>quote kind of summarizes it all. What they said was

0:25:04.720 --> 0:25:08.120
<v Speaker 4>that even the ones that correlate very strongly with the PSGs,

0:25:08.359 --> 0:25:12.680
<v Speaker 4>who like on average, agree with what the PSG readings are,

0:25:13.160 --> 0:25:19.080
<v Speaker 4>they said that quote this agreement masks substantial individual level inaccuracies,

0:25:19.440 --> 0:25:22.720
<v Speaker 4>prohibiting their use in clinical sleep medicine, as accurate assessment

0:25:22.800 --> 0:25:27.639
<v Speaker 4>of individual nights, including both nights with exceptionally low or

0:25:27.840 --> 0:25:32.560
<v Speaker 4>high quality and quantity, is essential for patient care. So

0:25:32.920 --> 0:25:35.920
<v Speaker 4>like on average, if you're just looking like population wide,

0:25:36.040 --> 0:25:39.040
<v Speaker 4>sure they decently, they do decently well, but on a

0:25:39.200 --> 0:25:42.000
<v Speaker 4>night to night basis, there's a lot of variability in

0:25:42.040 --> 0:25:44.440
<v Speaker 4>how well it's capturing you as an individual.

0:25:44.520 --> 0:25:46.440
<v Speaker 3>That makes sense. So you can't wake up in the

0:25:46.480 --> 0:25:47.920
<v Speaker 3>morning and go, how was last night?

0:25:48.119 --> 0:25:48.239
<v Speaker 6>Right?

0:25:48.440 --> 0:25:51.760
<v Speaker 3>Oh yeah, I see what happened? Yes, yeah, yeah, yeah,

0:25:51.800 --> 0:25:53.119
<v Speaker 3>like we did this morning.

0:25:52.960 --> 0:25:55.600
<v Speaker 4>We did like we've been doing the last couple of weeks.

0:25:56.000 --> 0:25:58.080
<v Speaker 4>So yeah, So that's just what I want to say

0:25:58.080 --> 0:26:00.400
<v Speaker 4>about those It's like they're not I.

0:26:00.400 --> 0:26:03.040
<v Speaker 3>Have heard that, Like, so they're not great at distinguishing

0:26:03.119 --> 0:26:06.359
<v Speaker 3>between among the stages of sleep, correct, But they are

0:26:06.560 --> 0:26:10.120
<v Speaker 3>okay at distinguishing awake and sleep.

0:26:09.960 --> 0:26:13.159
<v Speaker 4>Yes, so like to get like total duration, they're pretty decent.

0:26:13.640 --> 0:26:16.399
<v Speaker 4>But again, if you're trying to like understand especially like

0:26:16.600 --> 0:26:20.280
<v Speaker 4>quality what we call quality and like differentiating between the

0:26:20.320 --> 0:26:23.400
<v Speaker 4>different stages and things like that, or even if you're

0:26:23.400 --> 0:26:25.639
<v Speaker 4>trying to and this paper was specifically more looking at

0:26:25.680 --> 0:26:28.800
<v Speaker 4>people who have, say like obstructive sleep apnea or some

0:26:28.880 --> 0:26:30.800
<v Speaker 4>other kind of sleep disorder where you really want to

0:26:30.800 --> 0:26:33.760
<v Speaker 4>be able to get that fine detail, they weren't going

0:26:33.800 --> 0:26:36.919
<v Speaker 4>to be effective for that. And most of the studies

0:26:36.960 --> 0:26:40.240
<v Speaker 4>funded by the manufacturers are looking at like the general population,

0:26:40.359 --> 0:26:44.240
<v Speaker 4>so like healthy people without any diagnosed sleep disorders or anything.

0:26:44.560 --> 0:26:46.560
<v Speaker 4>So it's also a different population level.

0:26:46.320 --> 0:26:47.040
<v Speaker 6>That we're looking at, right.

0:26:48.000 --> 0:26:50.440
<v Speaker 4>So yeah, so that's what we know about those devices.

0:26:50.840 --> 0:26:55.520
<v Speaker 4>Moving on, before I get too deep into like why

0:26:55.600 --> 0:26:58.000
<v Speaker 4>what is happening? We know now what our brains are

0:26:58.000 --> 0:27:01.720
<v Speaker 4>doing as we monitor them, But before we get into

0:27:01.760 --> 0:27:04.200
<v Speaker 4>the maybe why of it, I want to touch base

0:27:04.280 --> 0:27:07.240
<v Speaker 4>really quickly on kind of how we sleep, Like what

0:27:07.359 --> 0:27:08.600
<v Speaker 4>is driving our sleep?

0:27:08.960 --> 0:27:12.600
<v Speaker 6>Okay, okay, sleep drive, sleep drive. That's the answer.

0:27:14.200 --> 0:27:15.639
<v Speaker 4>We did talk a little bit about this in our

0:27:15.680 --> 0:27:19.480
<v Speaker 4>circadian rhythm episode, yes, because our circadian rhythm is one

0:27:19.640 --> 0:27:22.520
<v Speaker 4>of the drivers of our sleep. So as a recap

0:27:22.560 --> 0:27:24.360
<v Speaker 4>so that you don't have to listen to that episode again.

0:27:25.280 --> 0:27:28.000
<v Speaker 4>There's a collection of cells deep in like the center

0:27:28.119 --> 0:27:32.000
<v Speaker 4>front of our brain behind our eyes, deep in our

0:27:32.000 --> 0:27:35.119
<v Speaker 4>brain that's called the super chismatic nucleus that is the

0:27:35.200 --> 0:27:39.280
<v Speaker 4>clock of our brain, then the SCN and it basically

0:27:39.359 --> 0:27:42.000
<v Speaker 4>generates this close to twenty four hour rhythm. All of

0:27:42.040 --> 0:27:44.080
<v Speaker 4>our cells do this to one degree or another.

0:27:43.840 --> 0:27:44.760
<v Speaker 3>Which is really cool.

0:27:44.840 --> 0:27:45.480
<v Speaker 6>It's so cool.

0:27:45.560 --> 0:27:48.320
<v Speaker 4>But this is like the master clock that keeps all

0:27:48.400 --> 0:27:52.000
<v Speaker 4>of our body functions in sync, mostly using signals from

0:27:52.080 --> 0:27:55.560
<v Speaker 4>light and dark from the sun. Right, and this circadian

0:27:55.600 --> 0:27:58.880
<v Speaker 4>clock of ours drives things like hormone production, among many

0:27:58.920 --> 0:28:03.200
<v Speaker 4>other things that help to promote sleep and awake at

0:28:03.200 --> 0:28:05.680
<v Speaker 4>the right times of day and night for us as

0:28:05.720 --> 0:28:10.760
<v Speaker 4>diurnal creatures. But our brain also has other mechanisms aside

0:28:10.760 --> 0:28:14.160
<v Speaker 4>from just the circadian clock that help to promote both

0:28:14.200 --> 0:28:17.760
<v Speaker 4>sleep and wakefulness or what's called arousal in the literature,

0:28:18.520 --> 0:28:21.359
<v Speaker 4>and it's mostly parts of our brain stem.

0:28:21.680 --> 0:28:22.000
<v Speaker 3>Right.

0:28:22.119 --> 0:28:25.320
<v Speaker 4>And our brain stem is like the deep back part

0:28:25.359 --> 0:28:27.639
<v Speaker 4>of our brain that connects to our spinal cord.

0:28:27.640 --> 0:28:28.119
<v Speaker 3>The stem.

0:28:28.320 --> 0:28:34.200
<v Speaker 4>The stem and parts of our brainstem release a whole

0:28:34.240 --> 0:28:39.680
<v Speaker 4>bunch of neurotransmitters that are involved mostly in promoting wakefulness

0:28:40.120 --> 0:28:44.200
<v Speaker 4>in wakefulness, right, so promoting us being awake and active

0:28:44.280 --> 0:28:48.560
<v Speaker 4>during the day. These are things like histamine, dopamine, nor adrenaline, serotonin,

0:28:48.960 --> 0:28:53.480
<v Speaker 4>all of these types of things that act in other

0:28:53.520 --> 0:28:55.640
<v Speaker 4>parts of our brain to be like, go do things

0:28:55.800 --> 0:28:59.440
<v Speaker 4>be awake? Yeah, that's what I imagine they're saying. And we

0:28:59.520 --> 0:29:02.480
<v Speaker 4>think that sleep ends up happening from a couple things

0:29:02.960 --> 0:29:06.080
<v Speaker 4>changing in our brain. One is that there's other parts

0:29:06.120 --> 0:29:08.640
<v Speaker 4>of our brain closer towards the front of it that

0:29:09.000 --> 0:29:13.320
<v Speaker 4>send signals to start to inhibit those awake signals. So like,

0:29:13.360 --> 0:29:15.520
<v Speaker 4>at some point in the day, other parts of our

0:29:15.560 --> 0:29:18.560
<v Speaker 4>brain will send signals and be like, hey, listen, histamine,

0:29:18.720 --> 0:29:21.200
<v Speaker 4>chill out a little bit. You've done enough today, So

0:29:21.240 --> 0:29:24.120
<v Speaker 4>they'll start to inhibit the release of histamine, ou rexin

0:29:24.240 --> 0:29:26.920
<v Speaker 4>or other signals that are saying be awake.

0:29:26.680 --> 0:29:29.000
<v Speaker 3>Be awake, right, and so okay.

0:29:29.400 --> 0:29:33.720
<v Speaker 4>And then the other part alway, Yeah, the other part

0:29:34.080 --> 0:29:36.920
<v Speaker 4>is that and this I think is really interesting we

0:29:37.080 --> 0:29:40.920
<v Speaker 4>also during the day, like just with our normal metabolism,

0:29:41.000 --> 0:29:43.600
<v Speaker 4>how our brain is functioning all day long, we are

0:29:43.600 --> 0:29:46.480
<v Speaker 4>making a bunch of stuff, and some of those things

0:29:46.640 --> 0:29:51.400
<v Speaker 4>we think act as like sleepy substances, where as they

0:29:51.440 --> 0:29:54.560
<v Speaker 4>build up in our brains throughout the day. As the

0:29:54.720 --> 0:29:59.880
<v Speaker 4>concentration of this substance or these substances really accumulate a

0:30:00.200 --> 0:30:04.840
<v Speaker 4>our body tissues, including our brain, they increase sleep pressure.

0:30:05.080 --> 0:30:05.440
<v Speaker 3>Yeah.

0:30:05.880 --> 0:30:06.360
<v Speaker 6>One of the.

0:30:06.360 --> 0:30:10.080
<v Speaker 4>Classic ones of these is a dentosine m HM and

0:30:10.160 --> 0:30:12.920
<v Speaker 4>a denizine we produce just as a byproduct of metabolism,

0:30:13.240 --> 0:30:16.040
<v Speaker 4>but as we produce that and it builds up in

0:30:16.080 --> 0:30:19.840
<v Speaker 4>our brain, it makes us more sleepy. Caffeine, Yes, we

0:30:19.840 --> 0:30:22.640
<v Speaker 4>talked about I was just about to ask about caffeine.

0:30:22.680 --> 0:30:27.120
<v Speaker 4>Caffeine inhibits the A dentizine receptors, so it tricks our

0:30:27.120 --> 0:30:29.160
<v Speaker 4>brain into thinking that we don't have a build up

0:30:29.240 --> 0:30:32.720
<v Speaker 4>of this sleepy substance when we actually do, and that's

0:30:32.760 --> 0:30:33.560
<v Speaker 4>how it works.

0:30:33.280 --> 0:30:34.040
<v Speaker 6>To keep us awake.

0:30:34.360 --> 0:30:37.360
<v Speaker 3>What about like mourning though, because if we're starting, are

0:30:37.400 --> 0:30:40.280
<v Speaker 3>we starting the day fresh? Everything's cleared out? Tell me

0:30:40.280 --> 0:30:43.360
<v Speaker 3>again about caffeine. It's been way too long since that episode.

0:30:42.960 --> 0:30:43.600
<v Speaker 6>So caffeine.

0:30:43.640 --> 0:30:46.480
<v Speaker 4>Basically like we because we're making a dentizine, just like

0:30:46.800 --> 0:30:49.920
<v Speaker 4>from metabolism, we break down atp we make a dentizine.

0:30:49.960 --> 0:30:51.600
<v Speaker 4>So throughout the day, it's just going to build up,

0:30:51.600 --> 0:30:53.720
<v Speaker 4>build up, build up, build up, and it's going to

0:30:53.760 --> 0:30:56.800
<v Speaker 4>bind to these receptors that do inhibition stuff.

0:30:56.800 --> 0:30:58.520
<v Speaker 6>That's like go to sleep, go to sleep.

0:30:59.040 --> 0:31:01.760
<v Speaker 4>Caffeine binds to those receptors, right, So it doesn't matter

0:31:01.800 --> 0:31:03.640
<v Speaker 4>how much a dentizy you have, there's nothing for them

0:31:03.640 --> 0:31:05.840
<v Speaker 4>to bind too, got it, because caffeine is blocking them,

0:31:06.120 --> 0:31:07.880
<v Speaker 4>and so it tricks our brain into being like there's

0:31:07.880 --> 0:31:09.840
<v Speaker 4>no identity here, I don't need to go to sleep,

0:31:10.080 --> 0:31:12.240
<v Speaker 4>and it is quite effective. Like there's so many studies

0:31:12.280 --> 0:31:15.080
<v Speaker 4>on like caffeine helping to alleviate sleepiness.

0:31:15.840 --> 0:31:20.720
<v Speaker 3>I think that like what is so interesting? Okay, speaking

0:31:20.720 --> 0:31:24.920
<v Speaker 3>for myself, Yeah, I feel like when if I am

0:31:24.960 --> 0:31:28.800
<v Speaker 3>sleepy during the day or in the evening or whatever,

0:31:28.960 --> 0:31:31.080
<v Speaker 3>just at any point in the day, I'm like, I

0:31:31.120 --> 0:31:33.480
<v Speaker 3>didn't get good sleep. I'm really tired, and I feel

0:31:33.480 --> 0:31:37.480
<v Speaker 3>like I expect that if to get really good sleep

0:31:37.640 --> 0:31:40.200
<v Speaker 3>or getting really good sleep makes me have no sleep drive,

0:31:40.240 --> 0:31:41.640
<v Speaker 3>and that's the ideal.

0:31:41.640 --> 0:31:43.440
<v Speaker 6>Oh, that's so interesting, you know what I mean? Yea,

0:31:43.720 --> 0:31:44.800
<v Speaker 6>I shouldn't ever be sleeping.

0:31:44.800 --> 0:31:47.200
<v Speaker 3>I shouldn't be sleepy until it's right before bed. And

0:31:47.240 --> 0:31:49.600
<v Speaker 3>now I just laid back, close my eyes and I'm

0:31:49.600 --> 0:31:51.320
<v Speaker 3>out boom, and I'm like, that would be great.

0:31:51.360 --> 0:31:53.320
<v Speaker 4>I would be great, But like it's not realistic.

0:31:53.360 --> 0:31:55.760
<v Speaker 3>It's not realistic. So sleep drive is so important, is

0:31:55.800 --> 0:31:56.360
<v Speaker 3>what I'm saying.

0:31:56.360 --> 0:31:58.840
<v Speaker 4>Well, and it's also it's interesting too because there is

0:31:58.880 --> 0:32:03.560
<v Speaker 4>this there's like a build up of our sleep drive

0:32:04.120 --> 0:32:07.440
<v Speaker 4>versus our circadian rhythm, and so sometimes those kind of

0:32:07.480 --> 0:32:09.640
<v Speaker 4>cross paths at a weird time where we can get

0:32:09.720 --> 0:32:12.760
<v Speaker 4>more sleepy than we expect in like the middle afternoon

0:32:12.960 --> 0:32:16.040
<v Speaker 4>or something like that. And so that's part of why

0:32:16.080 --> 0:32:18.080
<v Speaker 4>we might feel sleepy at times of day where we think, like,

0:32:18.120 --> 0:32:20.760
<v Speaker 4>I don't understand why I feel sleepy right now, and

0:32:20.800 --> 0:32:23.360
<v Speaker 4>it's just maybe because things are you know, it hasn't

0:32:23.360 --> 0:32:26.600
<v Speaker 4>overlapped in exactly the right way today kind of a thing,

0:32:26.640 --> 0:32:28.520
<v Speaker 4>But it doesn't necessarily mean that your sleep was terrible

0:32:28.560 --> 0:32:31.600
<v Speaker 4>the night before, right, So it is really interesting and

0:32:32.200 --> 0:32:35.280
<v Speaker 4>I'm probably not doing it justice, but there's obviously a

0:32:35.280 --> 0:32:36.720
<v Speaker 4>lot and it's not just a dentizy.

0:32:36.840 --> 0:32:36.959
<v Speaker 6>Right.

0:32:37.000 --> 0:32:38.760
<v Speaker 4>There's a lot of other substances that we think are

0:32:38.760 --> 0:32:41.600
<v Speaker 4>involved in this. So there's a lot that goes into

0:32:41.720 --> 0:32:44.240
<v Speaker 4>when and how we're sleepy. And some of it, too,

0:32:44.360 --> 0:32:47.080
<v Speaker 4>is genetics. So we know that some of our sleep

0:32:47.160 --> 0:32:50.320
<v Speaker 4>drive and a lot of our circadian rhythm, like whether

0:32:50.360 --> 0:32:53.680
<v Speaker 4>we are a night owl or a morning bird morning

0:32:54.000 --> 0:32:58.480
<v Speaker 4>morning lark, like, some of that is genetics. There's also

0:32:58.600 --> 0:33:02.360
<v Speaker 4>some genetic markers that we think are associated with like

0:33:02.720 --> 0:33:05.640
<v Speaker 4>very short sleep where people sleep very little but are

0:33:05.760 --> 0:33:06.480
<v Speaker 4>totally fine.

0:33:06.640 --> 0:33:09.200
<v Speaker 6>Oh yeah, right, And.

0:33:09.440 --> 0:33:14.760
<v Speaker 4>Our need for and our pattern of sleep also changes drastically.

0:33:14.040 --> 0:33:15.000
<v Speaker 6>Over our lifetime.

0:33:15.120 --> 0:33:15.480
<v Speaker 3>It does.

0:33:15.880 --> 0:33:18.400
<v Speaker 4>My favorite example of this are tiny babies.

0:33:18.480 --> 0:33:20.200
<v Speaker 6>Oh yeah, because.

0:33:20.280 --> 0:33:23.240
<v Speaker 4>Even though fetus is sleep when they are still in utero,

0:33:24.560 --> 0:33:27.320
<v Speaker 4>they do that like mostly in sync with the human

0:33:27.360 --> 0:33:32.840
<v Speaker 4>who's housing them. But once a baby is born, they

0:33:33.000 --> 0:33:35.840
<v Speaker 4>do not have a well defined circadian clock.

0:33:35.960 --> 0:33:38.720
<v Speaker 3>It's a mess, it is a disaster, yea.

0:33:39.880 --> 0:33:43.040
<v Speaker 4>Their circadian clock is much less than twenty four hours,

0:33:43.760 --> 0:33:47.840
<v Speaker 4>and their sleep pattern, like I said, a sleep cycle

0:33:47.880 --> 0:33:50.920
<v Speaker 4>is like ninety minutes. It's much shorter in babies, so

0:33:50.960 --> 0:33:53.480
<v Speaker 4>they're also cycling through a whole cycle of sleep in

0:33:53.600 --> 0:33:57.560
<v Speaker 4>much less time, yep, and their sleep pattern is totally random, yeah,

0:33:57.600 --> 0:34:00.520
<v Speaker 4>completely random, and they'll sleep up till like hours a

0:34:00.560 --> 0:34:04.320
<v Speaker 4>day like a dog, and not in any pattern that's

0:34:04.320 --> 0:34:08.080
<v Speaker 4>compatible with adult sleep patterns. And it's not until the

0:34:08.200 --> 0:34:11.280
<v Speaker 4>first like six to twelve months of life that they

0:34:11.320 --> 0:34:15.440
<v Speaker 4>start to consolidate their sleep into these twenty four hour patterns.

0:34:15.760 --> 0:34:18.560
<v Speaker 4>And because I fell into what is very common these

0:34:18.640 --> 0:34:22.239
<v Speaker 4>days of being very obsessive about my infant sleep when

0:34:22.239 --> 0:34:27.000
<v Speaker 4>my first child was born, I have data that you

0:34:27.040 --> 0:34:30.000
<v Speaker 4>can check out if you're watching the YouTube of my

0:34:30.160 --> 0:34:32.560
<v Speaker 4>kid's sleep pattern when he was an infant, and you

0:34:32.600 --> 0:34:35.080
<v Speaker 4>can see that it is literally all over the place.

0:34:35.160 --> 0:34:37.880
<v Speaker 3>I don't think anyone listening is surprised that you collected

0:34:37.960 --> 0:34:40.279
<v Speaker 3>data for how many months.

0:34:40.239 --> 0:34:42.160
<v Speaker 6>Of your first kids life? So many months?

0:34:42.400 --> 0:34:44.480
<v Speaker 3>Many? I mean the first probably fifteen. That's just one

0:34:44.520 --> 0:34:47.360
<v Speaker 3>aspect I had. The amount of date I remember too.

0:34:47.320 --> 0:34:49.279
<v Speaker 4>There was so much. Yeah, the second one I didn't

0:34:49.320 --> 0:34:52.759
<v Speaker 4>do any of that. But you can then see that

0:34:52.880 --> 0:34:56.320
<v Speaker 4>by eleven or twelve months, even though sleep wasn't great,

0:34:56.719 --> 0:34:59.200
<v Speaker 4>you can see this twenty four hour pattern emerge where

0:34:59.239 --> 0:35:00.879
<v Speaker 4>there's like a nap in the middle of the day

0:35:01.080 --> 0:35:03.480
<v Speaker 4>or maybe two naps, But then the majority of sleep

0:35:03.560 --> 0:35:06.560
<v Speaker 4>is happening over the night time period, and that is

0:35:06.600 --> 0:35:09.400
<v Speaker 4>because that's how long it really takes for infants to

0:35:09.480 --> 0:35:11.600
<v Speaker 4>develop this twenty four hour pattern, which I think is

0:35:11.640 --> 0:35:15.120
<v Speaker 4>just so interesting. And then the amount of sleep that

0:35:15.160 --> 0:35:17.960
<v Speaker 4>we need over our lifetime changes too. Kids need a

0:35:17.960 --> 0:35:21.240
<v Speaker 4>lot more sleep. Teenagers we talked about in our circadian

0:35:21.320 --> 0:35:24.920
<v Speaker 4>rhythm episode do actually have a shift in their circadian

0:35:25.000 --> 0:35:29.120
<v Speaker 4>rhythm towards night owl tendencies, and so they tend to

0:35:29.160 --> 0:35:33.040
<v Speaker 4>sleep later and wake up later, and that can put

0:35:33.040 --> 0:35:36.160
<v Speaker 4>them out of sync with our modern society. And then

0:35:36.200 --> 0:35:38.640
<v Speaker 4>as adults, especially older adults, a lot of times we

0:35:38.719 --> 0:35:41.080
<v Speaker 4>don't need quite as much sleep. So the amount of

0:35:41.080 --> 0:35:46.279
<v Speaker 4>sleep that we actually need varies. So why do we

0:35:46.320 --> 0:35:52.080
<v Speaker 4>need this much sleep? Like why I'm I'm but it's

0:35:52.120 --> 0:35:54.960
<v Speaker 4>a rhetorical question that I'm going to try and answer,

0:35:55.200 --> 0:35:57.960
<v Speaker 4>asking the room ask does anybody know?

0:35:58.040 --> 0:35:58.719
<v Speaker 3>Does anyone know?

0:36:01.520 --> 0:36:03.600
<v Speaker 6>We still like, we still don't really know.

0:36:04.280 --> 0:36:06.560
<v Speaker 3>We don't exactly.

0:36:05.960 --> 0:36:08.040
<v Speaker 4>What our brains are doing in terms of the function

0:36:08.320 --> 0:36:09.439
<v Speaker 4>of our sleep, Like.

0:36:09.360 --> 0:36:11.799
<v Speaker 3>We know what happens. We know there are bad things

0:36:11.800 --> 0:36:14.000
<v Speaker 3>that happen when we don't get enough skit correct and

0:36:14.160 --> 0:36:16.160
<v Speaker 3>that's a lot about that. That's what guides a lot

0:36:16.200 --> 0:36:18.560
<v Speaker 3>of our assumptions about why sleep is important.

0:36:18.719 --> 0:36:21.120
<v Speaker 4>Yes, and like what our brains are really like doing

0:36:21.280 --> 0:36:24.920
<v Speaker 4>during sleep. Yeah, so we do see and the one

0:36:24.960 --> 0:36:27.440
<v Speaker 4>of the hypotheses I'll kind of walk through the biggest ones.

0:36:27.760 --> 0:36:29.759
<v Speaker 4>One of the hypotheses is that it is kind of

0:36:29.920 --> 0:36:33.520
<v Speaker 4>energy conservation during sleep, and that is because we do

0:36:33.600 --> 0:36:36.880
<v Speaker 4>see a relative decrease in metabolism during sleep.

0:36:37.320 --> 0:36:41.360
<v Speaker 3>However, not really, I mean especially yeah, yeah.

0:36:41.200 --> 0:36:43.960
<v Speaker 4>Yeah, especially if you're looking at total body metabolism, Like

0:36:44.080 --> 0:36:47.160
<v Speaker 4>during rem sleep, our metabolism is essentially the same as

0:36:47.200 --> 0:36:52.720
<v Speaker 4>when we're awake. Our brain metabolism does decrease substantially, especially

0:36:52.840 --> 0:36:55.920
<v Speaker 4>during non rem sleep, but again that's only a portion

0:36:56.200 --> 0:36:59.200
<v Speaker 4>of our total sleep, right, and it's nothing like like

0:36:59.239 --> 0:37:02.320
<v Speaker 4>our sleep is nothing like hibernation or torpor or something

0:37:02.360 --> 0:37:04.480
<v Speaker 4>where we're truly decreasing metabolism.

0:37:04.840 --> 0:37:07.560
<v Speaker 6>So that's clearly not the whole story. Could be part

0:37:07.560 --> 0:37:07.799
<v Speaker 6>of it.

0:37:08.640 --> 0:37:11.239
<v Speaker 4>There is a lot of evidence that we see changes

0:37:11.280 --> 0:37:14.839
<v Speaker 4>in things like gene expression, so like certain things turn

0:37:15.000 --> 0:37:17.799
<v Speaker 4>on and certain things turn off when we're asleep. That

0:37:17.920 --> 0:37:20.759
<v Speaker 4>only happens when we're asleep, So we think that must

0:37:20.760 --> 0:37:25.040
<v Speaker 4>be important. But why exactly We don't know. I mean, yeah,

0:37:25.360 --> 0:37:28.040
<v Speaker 4>because I talked about these like sleepy substances and things

0:37:28.120 --> 0:37:29.960
<v Speaker 4>like that. We do think that there's sort of like

0:37:30.040 --> 0:37:33.480
<v Speaker 4>a clean out of the build up of these neurotransmitters

0:37:33.480 --> 0:37:34.640
<v Speaker 4>that happens during the day.

0:37:34.960 --> 0:37:35.520
<v Speaker 3>Detox.

0:37:35.960 --> 0:37:37.799
<v Speaker 6>Yeah, brain detox. I hate that word.

0:37:37.840 --> 0:37:40.239
<v Speaker 4>It's not accurate, but but we do see like an

0:37:40.280 --> 0:37:44.000
<v Speaker 4>increase of cerebral spinal fluid flow during sleep and things.

0:37:44.120 --> 0:37:47.960
<v Speaker 3>Wash was so I've just heard it described getting rid

0:37:48.000 --> 0:37:51.480
<v Speaker 3>of all these neurotransmitters and replenishing others. It's very like

0:37:51.520 --> 0:37:54.319
<v Speaker 3>it's a very satisfying image to think about, just like

0:37:55.800 --> 0:37:58.040
<v Speaker 3>just like a gentle washing of the brain.

0:37:58.160 --> 0:38:01.640
<v Speaker 4>That's what you're hearing as you all asleep anyways, great

0:38:01.640 --> 0:38:06.960
<v Speaker 4>white noise. How much of is that the function of sleep?

0:38:07.320 --> 0:38:07.920
<v Speaker 6>Maybe?

0:38:08.160 --> 0:38:08.399
<v Speaker 3>Yeah.

0:38:08.800 --> 0:38:11.720
<v Speaker 4>And then one of the biggest hypotheses is that sleep

0:38:11.800 --> 0:38:14.320
<v Speaker 4>is required for consolidation of our memory.

0:38:14.040 --> 0:38:18.000
<v Speaker 3>Memory consolidation. Why do we have to whisper?

0:38:18.239 --> 0:38:21.600
<v Speaker 4>I don't know, And we do know there's something called

0:38:21.680 --> 0:38:25.400
<v Speaker 4>sleep dependent memory processing where there's done. We've done a

0:38:25.400 --> 0:38:27.480
<v Speaker 4>bunch of studies where if you give humans or animals

0:38:27.520 --> 0:38:29.919
<v Speaker 4>a task and then deprive them of sleep. They never

0:38:29.960 --> 0:38:32.440
<v Speaker 4>really learn that task to the same degree that they

0:38:32.480 --> 0:38:36.239
<v Speaker 4>would if you let them sleep after it. But even this,

0:38:36.600 --> 0:38:39.239
<v Speaker 4>the data is a little it's a little bit controversial

0:38:39.320 --> 0:38:43.120
<v Speaker 4>still that like is this truly the function of sleep,

0:38:43.320 --> 0:38:46.440
<v Speaker 4>especially because it's like we're trying to compare human brains

0:38:46.480 --> 0:38:49.560
<v Speaker 4>to like, well, we don't have like lots of animals

0:38:49.560 --> 0:38:52.160
<v Speaker 4>sleep that don't we don't know anything about their memory.

0:38:52.200 --> 0:38:54.520
<v Speaker 6>Oh you'll get to it. You'll get it with those eyebrows.

0:38:54.520 --> 0:38:57.319
<v Speaker 3>Sorry, I love it, but but.

0:38:57.320 --> 0:38:58.759
<v Speaker 4>Yeah, that's that is one of the kind of big

0:38:58.840 --> 0:39:01.760
<v Speaker 4>hypotheses that like sleep is essential for our memory.

0:39:03.520 --> 0:39:08.240
<v Speaker 3>Okay, but like I don't understand why that's controversial, only

0:39:08.320 --> 0:39:11.200
<v Speaker 3>in that if it's overstated that this is the function.

0:39:11.239 --> 0:39:12.960
<v Speaker 6>That's what it is. That's what it is. It's that

0:39:13.000 --> 0:39:14.400
<v Speaker 6>it like we know that it's essential.

0:39:14.440 --> 0:39:15.160
<v Speaker 3>It is a function.

0:39:15.320 --> 0:39:17.200
<v Speaker 6>It is a function. But I think I think.

0:39:17.000 --> 0:39:19.279
<v Speaker 4>That it's just that people are so obsessed with this

0:39:19.360 --> 0:39:22.040
<v Speaker 4>idea that there is like a reason for things.

0:39:22.280 --> 0:39:27.879
<v Speaker 3>Nah, that's just sorry, but that's true, right, Like it's

0:39:27.960 --> 0:39:31.560
<v Speaker 3>not we're not going to get to oh like this

0:39:31.800 --> 0:39:35.200
<v Speaker 3>like like Laurie will not will not arrive.

0:39:35.320 --> 0:39:37.800
<v Speaker 6>It's a bunch of different things happen when we sleep.

0:39:38.000 --> 0:39:41.640
<v Speaker 3>I know I'm not satisfying as right, we found it.

0:39:41.800 --> 0:39:45.319
<v Speaker 3>Here is the answer, the reason for sleep. Right the

0:39:45.640 --> 0:39:49.160
<v Speaker 3>singular point, that's ridiculous.

0:39:49.320 --> 0:39:51.319
<v Speaker 4>We sleep for a bunch of different reasons, and as

0:39:51.360 --> 0:39:52.440
<v Speaker 4>we'll see you next episode.

0:39:52.480 --> 0:39:53.840
<v Speaker 6>If we don't, there's.

0:39:53.680 --> 0:39:57.480
<v Speaker 3>A problem a lot of different things beyond memory.

0:39:58.080 --> 0:40:01.000
<v Speaker 6>But that's for next episode.

0:40:01.000 --> 0:40:04.200
<v Speaker 4>So, Aaron, what I'd like to know from you please

0:40:04.840 --> 0:40:07.880
<v Speaker 4>is like, obviously, I know my dog sleeps.

0:40:08.080 --> 0:40:09.560
<v Speaker 6>My cat all he does is sleep?

0:40:09.960 --> 0:40:10.360
<v Speaker 3>Yeah?

0:40:10.520 --> 0:40:12.240
<v Speaker 6>Do all animals sleep?

0:40:12.320 --> 0:40:12.400
<v Speaker 5>Like?

0:40:12.560 --> 0:40:13.200
<v Speaker 3>Oh?

0:40:13.520 --> 0:40:15.880
<v Speaker 6>Do they?

0:40:16.600 --> 0:40:32.799
<v Speaker 7>I'll tell you, Okay.

0:40:36.080 --> 0:40:41.440
<v Speaker 3>In nineteen seventy one, renowned sleep researcher Alan Rechschaffen wrote

0:40:41.480 --> 0:40:45.760
<v Speaker 3>that quote, if sleep does not serve an absolute vital function,

0:40:46.120 --> 0:40:49.839
<v Speaker 3>then it is the biggest mistake the evolutionary process has

0:40:49.920 --> 0:40:52.160
<v Speaker 3>ever made.

0:40:52.200 --> 0:40:54.719
<v Speaker 6>I love that, right. Yeah, okay, So.

0:40:55.120 --> 0:40:58.319
<v Speaker 3>Let's break that statement down first. Why would sleep be

0:40:58.360 --> 0:41:03.120
<v Speaker 3>a mistake? Gives us vulnerable to predators and bugs and

0:41:03.200 --> 0:41:06.840
<v Speaker 3>parasites transmitted by bugs, and it takes up precious time

0:41:06.880 --> 0:41:08.880
<v Speaker 3>that we could be using to do something else like

0:41:09.040 --> 0:41:11.320
<v Speaker 3>forage or mate or socialize or read a book, or

0:41:11.360 --> 0:41:13.560
<v Speaker 3>do your taxes or play with your kids, or exercise,

0:41:13.640 --> 0:41:15.319
<v Speaker 3>or cook a nice meal, or work more hours at

0:41:15.320 --> 0:41:19.000
<v Speaker 3>the office. It's so true, so many things. I know

0:41:19.080 --> 0:41:21.240
<v Speaker 3>that many tech bros view sleep as a mistake.

0:41:21.320 --> 0:41:22.799
<v Speaker 6>Oh yeah, you don't even need it.

0:41:22.920 --> 0:41:24.640
<v Speaker 3>You don't need it, You could just wake up it

0:41:24.680 --> 0:41:31.759
<v Speaker 3>three am. Sorry, Wow, I think something just happened there.

0:41:32.120 --> 0:41:35.680
<v Speaker 3>I liked it, but I mean that aside, though, I

0:41:35.719 --> 0:41:37.880
<v Speaker 3>do think that most of us have, at one point

0:41:37.880 --> 0:41:39.600
<v Speaker 3>in our lives wish that we didn't have to sleep

0:41:39.600 --> 0:41:42.080
<v Speaker 3>as much as we did because we could get so

0:41:42.200 --> 0:41:44.680
<v Speaker 3>much more done. I know that I have wished that,

0:41:44.920 --> 0:41:47.400
<v Speaker 3>Like gosh, I could just if I didn't have to

0:41:48.200 --> 0:41:51.239
<v Speaker 3>sleep as much, I could do things I wanted to do.

0:41:52.000 --> 0:41:55.480
<v Speaker 3>It is undeniable that sleep is costly, but it would

0:41:55.520 --> 0:41:58.359
<v Speaker 3>only be a mistake if we didn't get anything out

0:41:58.400 --> 0:42:02.280
<v Speaker 3>of it. Okay, Second, does sleep serve a vital function?

0:42:02.680 --> 0:42:05.240
<v Speaker 3>From what you just told us, erin, it serves multiple

0:42:05.480 --> 0:42:10.080
<v Speaker 3>vital functions. We may not know precisely how sleep helps

0:42:10.160 --> 0:42:12.160
<v Speaker 3>us and the pathways that it works along, but we

0:42:12.200 --> 0:42:16.960
<v Speaker 3>know from experimental and observational research that sleep deprivation is harmful,

0:42:17.160 --> 0:42:19.320
<v Speaker 3>and that when we lose out on sleep, our body

0:42:19.360 --> 0:42:23.560
<v Speaker 3>compensates by increasing sleep. There's like sleep homeostasis kind of

0:42:23.719 --> 0:42:27.080
<v Speaker 3>totally okay, So now why would sleep be the biggest

0:42:27.640 --> 0:42:31.360
<v Speaker 3>mistake that the evolutionary process ever made? Because sleep is

0:42:31.560 --> 0:42:33.840
<v Speaker 3>ubiquitous across the animal kingdom?

0:42:34.040 --> 0:42:34.440
<v Speaker 6>Love this.

0:42:35.400 --> 0:42:38.319
<v Speaker 3>At this point in our understanding of sleep, it would

0:42:38.320 --> 0:42:41.120
<v Speaker 3>be much harder to prove that an animal doesn't sleep

0:42:41.760 --> 0:42:45.960
<v Speaker 3>than determine that it does. Even cavefish species like the

0:42:46.000 --> 0:42:49.640
<v Speaker 3>Mexican blind cavefish, which has lost eyes and pigmentation and

0:42:49.719 --> 0:42:51.640
<v Speaker 3>much of their circadian rhythm pattern.

0:42:51.400 --> 0:42:54.520
<v Speaker 6>Because they're in the completely.

0:42:53.640 --> 0:42:58.000
<v Speaker 3>Darkness, they still retain some sleep. Wow, it's reduced as

0:42:58.080 --> 0:43:01.120
<v Speaker 3>much as like eighty percent, but still there are indications

0:43:01.160 --> 0:43:03.920
<v Speaker 3>of sleep. What does indications of sleep means?

0:43:04.040 --> 0:43:04.799
<v Speaker 6>Especially in a fit?

0:43:05.080 --> 0:43:05.520
<v Speaker 3>I know?

0:43:05.840 --> 0:43:06.160
<v Speaker 6>Okay?

0:43:07.200 --> 0:43:09.560
<v Speaker 3>So for us to recognize and measure sleep in non

0:43:09.680 --> 0:43:13.279
<v Speaker 3>human animals, we have to step outside of our human box. So,

0:43:13.760 --> 0:43:16.600
<v Speaker 3>for one, there's the logistical challenge of recording an EEG

0:43:16.760 --> 0:43:17.880
<v Speaker 3>on a Mexican blind.

0:43:17.680 --> 0:43:19.239
<v Speaker 6>Kfish, Like that's can you do it?

0:43:19.280 --> 0:43:23.719
<v Speaker 3>Can you do it? I don't know, it's pretty difficult, challenging.

0:43:24.040 --> 0:43:25.960
<v Speaker 3>And then for two, we want to be able to

0:43:26.000 --> 0:43:29.759
<v Speaker 3>observe sleep in more natural settings. And for three it's

0:43:29.760 --> 0:43:32.680
<v Speaker 3>important to step back from our tendency to make humans

0:43:32.880 --> 0:43:34.799
<v Speaker 3>like the ideal of the norm, right, like, oh, if

0:43:34.800 --> 0:43:37.359
<v Speaker 3>you don't sleep like a human, are you sleeping at all?

0:43:39.640 --> 0:43:43.520
<v Speaker 3>So we can measure sleep elect electrophysiologically using EEGs, and

0:43:43.520 --> 0:43:45.719
<v Speaker 3>we have done that for a number of animal species,

0:43:46.360 --> 0:43:50.359
<v Speaker 3>and we can measure it behaviorally. So researchers use five

0:43:50.440 --> 0:43:53.880
<v Speaker 3>criteria to say that an animal sleeps. Number one, and

0:43:53.920 --> 0:43:56.360
<v Speaker 3>it's very similar like you mentioned some of these. Number

0:43:56.360 --> 0:44:01.400
<v Speaker 3>one prolonged behavioral quiescence basically stop doing stuff, not doing stuff,

0:44:01.600 --> 0:44:07.040
<v Speaker 3>not doing it. Number two reversible upon stimulation, unlike like

0:44:07.080 --> 0:44:11.600
<v Speaker 3>you said, torpor or coma. Three a species specific posture,

0:44:11.600 --> 0:44:14.640
<v Speaker 3>it's not just him, and like laying down or tucking

0:44:14.640 --> 0:44:17.360
<v Speaker 3>your antenna away. And then I have a picture of

0:44:17.400 --> 0:44:20.680
<v Speaker 3>my dog in bagel formation, which is a very he's

0:44:20.800 --> 0:44:25.279
<v Speaker 3>one of his favorites. Number four increased arousal threshold. So

0:44:25.320 --> 0:44:29.560
<v Speaker 3>you need a louder or like more substantial stimulus like

0:44:29.600 --> 0:44:31.560
<v Speaker 3>a noise to get you to respond that if you're awake.

0:44:31.680 --> 0:44:35.080
<v Speaker 4>Decreased response to stimulations you maybe like whispering like hey

0:44:35.360 --> 0:44:36.160
<v Speaker 4>wake up now.

0:44:36.160 --> 0:44:39.120
<v Speaker 6>Would you please roll over? Might not do it?

0:44:39.360 --> 0:44:44.440
<v Speaker 3>You're snoring, So like your senses are dulled and number

0:44:44.440 --> 0:44:47.640
<v Speaker 3>five rebound after being sleep deprived, you sleep more. And

0:44:47.680 --> 0:44:49.239
<v Speaker 3>so these are the things that we can use to

0:44:49.280 --> 0:44:53.319
<v Speaker 3>say that animal is sleeping because it's doing all these things.

0:44:53.680 --> 0:44:57.360
<v Speaker 3>And so using these criteria, we can describe and define

0:44:57.400 --> 0:45:02.839
<v Speaker 3>sleep in a huge array of species like pond snails, octopus, cuttlefish,

0:45:03.040 --> 0:45:04.800
<v Speaker 3>which may even exhibit rem sleep.

0:45:05.000 --> 0:45:11.680
<v Speaker 5>Sorry snails, snails, Oh, it gets even more extreme, yeah, lobsters, mice, armadillos, flies,

0:45:12.280 --> 0:45:15.719
<v Speaker 5>And funnily enough, whether animals truly sleep is kind of

0:45:15.719 --> 0:45:16.920
<v Speaker 5>a more recent question.

0:45:17.200 --> 0:45:21.440
<v Speaker 3>Ancient scholars like Aristotle fully believed that animals sleep. Of

0:45:21.440 --> 0:45:24.239
<v Speaker 3>course they sleep. And there's an adorable quote I'm going

0:45:24.280 --> 0:45:26.680
<v Speaker 3>to read to you from an eighteen sixty five book

0:45:26.719 --> 0:45:31.080
<v Speaker 3>called Yearbook of Facts. Quote. An insect composes itself to

0:45:31.160 --> 0:45:34.320
<v Speaker 3>sleep with its antenna folded. Some of the beetles adjust

0:45:34.400 --> 0:45:37.640
<v Speaker 3>them to their breast. The butterfly seeks some particular aspect

0:45:37.680 --> 0:45:40.680
<v Speaker 3>of a tree and folds vertically its wings, throws back

0:45:40.680 --> 0:45:45.640
<v Speaker 3>the antennae, and remains motionless and insensible to all external circumstances.

0:45:46.160 --> 0:45:50.680
<v Speaker 3>When caterpillars, which are insatiable feeders, are observed resting, immovable

0:45:50.680 --> 0:45:53.040
<v Speaker 3>with their heads down. They are asleep.

0:45:53.960 --> 0:45:54.400
<v Speaker 6>I love it.

0:45:54.480 --> 0:45:57.600
<v Speaker 4>Quote like we don't eat an eeg bro look at

0:45:57.600 --> 0:45:58.160
<v Speaker 4>the book.

0:45:57.960 --> 0:46:01.880
<v Speaker 3>At their little antennae, they're all yeah.

0:46:01.440 --> 0:46:04.920
<v Speaker 6>And you can hear them quietly towering. Yeah. So it's

0:46:05.040 --> 0:46:05.920
<v Speaker 6>so cute.

0:46:06.640 --> 0:46:09.000
<v Speaker 3>But it's still helpful to have these specific standards for

0:46:09.040 --> 0:46:11.640
<v Speaker 3>what counts as sleep because we can then also try

0:46:11.680 --> 0:46:15.920
<v Speaker 3>to trace the genetic basis and neurological pathways of sleep. Okay, So,

0:46:15.960 --> 0:46:21.160
<v Speaker 3>for example, Sea Elegance, the research world's favorite worm, contains

0:46:21.200 --> 0:46:24.520
<v Speaker 3>a mere three hundred and two neurons, wow, compared to

0:46:24.600 --> 0:46:26.800
<v Speaker 3>an adult fruitfly, which has two hundred and fifty thousand.

0:46:27.360 --> 0:46:31.480
<v Speaker 3>So right, and since Sea Elegant sleeps, we can map

0:46:31.520 --> 0:46:33.680
<v Speaker 3>out the neural pathway of sleep at least in that

0:46:33.719 --> 0:46:34.839
<v Speaker 3>critter because there are so few.

0:46:35.719 --> 0:46:36.000
<v Speaker 6>Wow.

0:46:36.040 --> 0:46:39.600
<v Speaker 3>That's really cool, Okay, really cool. But what's even more

0:46:39.640 --> 0:46:42.719
<v Speaker 3>amazing is that this isn't the quote unquote like simplest

0:46:43.160 --> 0:46:48.759
<v Speaker 3>creature to sleep. Using those behavioral criteria, researchers concluded that

0:46:48.840 --> 0:46:52.959
<v Speaker 3>the upside down jellyfish in the genus Cassiopeia sleep.

0:46:53.160 --> 0:46:55.520
<v Speaker 6>Jellyfish jellyfish jellyfish.

0:46:56.160 --> 0:46:59.560
<v Speaker 3>Unlike sea elegans, these jellyfish. They don't have a central

0:46:59.560 --> 0:47:03.279
<v Speaker 3>nervous just a nerve net like rings of neurons, And

0:47:03.320 --> 0:47:06.560
<v Speaker 3>so scientists observed that when the jellyfish is active, their

0:47:06.600 --> 0:47:10.120
<v Speaker 3>nerve net contracts and causes pulsing behavior that lets them

0:47:10.160 --> 0:47:13.880
<v Speaker 3>feed and get nutrients. But at night, the pulsing behavior

0:47:13.920 --> 0:47:17.960
<v Speaker 3>reduces and they become less responsive to external stimuli. And

0:47:18.000 --> 0:47:20.520
<v Speaker 3>then when you disrupt their resting time, like you keep

0:47:20.680 --> 0:47:24.520
<v Speaker 3>splashing them with water waves or whatever, they will pulse

0:47:24.600 --> 0:47:27.719
<v Speaker 3>even less the next day, indicative of sleep rebound. Oh

0:47:27.760 --> 0:47:31.600
<v Speaker 3>my gosh, right, I love it, isn't that wild? Yes,

0:47:32.080 --> 0:47:35.600
<v Speaker 3>And so this means that sleep likely evolved before a

0:47:35.640 --> 0:47:36.720
<v Speaker 3>central nervous system.

0:47:37.239 --> 0:47:42.120
<v Speaker 4>That is so interesting, huge, huge, especially the context of

0:47:42.200 --> 0:47:43.520
<v Speaker 4>memory and stuff like that.

0:47:43.520 --> 0:47:48.520
<v Speaker 8>Right, I mean, okay, yeah, okay, yeah, yeah yeah. But

0:47:48.640 --> 0:47:51.359
<v Speaker 8>like this is this is an ancient and widespread thing,

0:47:51.400 --> 0:47:53.879
<v Speaker 8>and so given how ancient and widespread it is, it

0:47:53.960 --> 0:47:56.759
<v Speaker 8>doesn't really seem like uh.

0:47:56.520 --> 0:47:59.160
<v Speaker 3>Sleep is it is a mistake. And as far as

0:47:59.239 --> 0:48:01.719
<v Speaker 3>I mean, sleep doesn't get fossilized because it's a behavior.

0:48:02.800 --> 0:48:04.960
<v Speaker 3>But as far as we can tell, no species has

0:48:05.200 --> 0:48:08.000
<v Speaker 3>entirely lost the capacity for sleep, meaning that it is

0:48:08.040 --> 0:48:13.400
<v Speaker 3>still so vital too existence. Yeah. Yeah, sleep disturbances or

0:48:13.440 --> 0:48:16.280
<v Speaker 3>a lack of sleep can have profound effects on health

0:48:16.320 --> 0:48:22.320
<v Speaker 3>and overall performance, vulnerability to infections, attentiveness, reaction time, memory formation.

0:48:22.920 --> 0:48:26.440
<v Speaker 3>Mollusks that have been deprived of sleep cannot form new memories.

0:48:27.400 --> 0:48:30.600
<v Speaker 4>So like, how do you measure a mollusc's memory?

0:48:30.760 --> 0:48:33.000
<v Speaker 3>I don't know. I didn't go that deep.

0:48:34.040 --> 0:48:34.880
<v Speaker 6>Now I need to.

0:48:35.440 --> 0:48:40.080
<v Speaker 3>I will find the paper, right, And then there are

0:48:40.120 --> 0:48:43.560
<v Speaker 3>a few gruesome experiments where rats that were completely deprived

0:48:43.600 --> 0:48:45.640
<v Speaker 3>of sleep for like a long period of time died.

0:48:45.840 --> 0:48:46.799
<v Speaker 6>Oh my god, they died.

0:48:46.920 --> 0:48:51.320
<v Speaker 3>Yeah. The world record for no sleep, sleep deprivation and

0:48:51.400 --> 0:48:54.200
<v Speaker 3>a human is eleven days. I heard that two hundred

0:48:54.200 --> 0:48:57.040
<v Speaker 3>and sixty four hours, held by a San Diego teenager

0:48:57.120 --> 0:49:00.840
<v Speaker 3>named Randy Gardner who in nineteen sixty five played basketball

0:49:00.880 --> 0:49:04.319
<v Speaker 3>throughout the night to stay awake. But apparently, like I

0:49:04.360 --> 0:49:07.200
<v Speaker 3>think in I don't know how they determine this, but

0:49:07.680 --> 0:49:10.160
<v Speaker 3>they were discovering that he was taking like microground, as

0:49:10.400 --> 0:49:12.200
<v Speaker 3>of course he was, and so was it truly two

0:49:12.239 --> 0:49:13.520
<v Speaker 3>hundred and sixty four hours?

0:49:13.600 --> 0:49:13.799
<v Speaker 1>You know?

0:49:14.040 --> 0:49:16.040
<v Speaker 6>Yeah, I mean his brain was falling asleep. He just

0:49:16.080 --> 0:49:16.560
<v Speaker 6>did not know it.

0:49:16.680 --> 0:49:18.560
<v Speaker 3>He didn't know it, and no one else knew that

0:49:18.600 --> 0:49:20.680
<v Speaker 3>he was. Yeah, but any that's like, I do not

0:49:20.760 --> 0:49:24.239
<v Speaker 3>try that at home situation. Yeah, So even though we

0:49:24.280 --> 0:49:27.080
<v Speaker 3>all sleep in some capacity, we don't all sleep the same.

0:49:27.600 --> 0:49:31.120
<v Speaker 3>Elephants sleep about half the time that humans do, four

0:49:31.160 --> 0:49:33.840
<v Speaker 3>hours compared to our eight, which is really more like

0:49:33.880 --> 0:49:38.040
<v Speaker 3>six to seven. Brown bats sleep about nineteen hours a day,

0:49:38.360 --> 0:49:41.880
<v Speaker 3>similar to Armadilla's. Koala's sleep even longer, twenty to twenty

0:49:41.880 --> 0:49:46.120
<v Speaker 3>two hours. Meanwhile, donkeys sleep about three hours. Cats sleep

0:49:46.200 --> 0:49:47.680
<v Speaker 3>twelve and a half hours a day, which seems like

0:49:47.680 --> 0:49:48.720
<v Speaker 3>an underrested.

0:49:48.320 --> 0:49:49.400
<v Speaker 6>Absolutely an addressment.

0:49:49.840 --> 0:49:53.359
<v Speaker 3>Goats five point three on average, guinea pigs nine point four.

0:49:53.400 --> 0:49:55.879
<v Speaker 3>I mean, just to show you, it's all over the map.

0:49:56.680 --> 0:49:59.160
<v Speaker 3>And really many of these sleep duration estimates we do

0:49:59.200 --> 0:50:00.719
<v Speaker 3>have to take with a grain of s because like

0:50:00.800 --> 0:50:03.640
<v Speaker 3>we're measuring sleep in the lab, and so there tends

0:50:03.680 --> 0:50:08.680
<v Speaker 3>to be a bias towards like longer sleep because they're like,

0:50:08.719 --> 0:50:11.719
<v Speaker 3>I don't have to worry about predators. I've got food here,

0:50:12.120 --> 0:50:14.759
<v Speaker 3>i've got water, I'm chillen. Might as well take a nap,

0:50:14.840 --> 0:50:18.520
<v Speaker 3>might as well just nap all the time. But even still,

0:50:18.560 --> 0:50:21.000
<v Speaker 3>we do have this huge variation in how much sleep

0:50:21.000 --> 0:50:25.080
<v Speaker 3>different species need. But duration is just one component of sleep,

0:50:25.239 --> 0:50:28.000
<v Speaker 3>as we talked about. There's also whether you sleep in

0:50:28.080 --> 0:50:31.480
<v Speaker 3>one big chunk or multiple times throughout the day or

0:50:31.520 --> 0:50:34.760
<v Speaker 3>throughout the night, like monophasic sleep is one big chunk,

0:50:35.120 --> 0:50:37.920
<v Speaker 3>which is what humans usually do big asterisk on that,

0:50:38.760 --> 0:50:41.680
<v Speaker 3>by phasic sleep, which is two chunks, which is what

0:50:41.760 --> 0:50:45.560
<v Speaker 3>humans may be used to do, asterisk on that, or

0:50:45.760 --> 0:50:51.520
<v Speaker 3>polyphasic sleep like multiple chunks, like a dog who sleeps constantly. Yeah.

0:50:52.200 --> 0:50:54.200
<v Speaker 3>Whether you tend to sleep during the night time, during

0:50:54.320 --> 0:50:57.160
<v Speaker 3>or during the day is another big component of this,

0:50:57.239 --> 0:50:59.840
<v Speaker 3>like a red tailed hawk versus a barn owl for instance,

0:51:00.160 --> 0:51:03.279
<v Speaker 3>talking birds and not all owls are nocturnal. A lot

0:51:03.360 --> 0:51:05.600
<v Speaker 3>are crepuscular, So it took me a while to find

0:51:05.600 --> 0:51:09.319
<v Speaker 3>one that I was like, it's a great word, crepuscular. Yeah,

0:51:09.320 --> 0:51:13.040
<v Speaker 3>it's very good. There's also whether or not you have remsleep.

0:51:13.239 --> 0:51:16.880
<v Speaker 3>So generally speaking, mammals and birds are the only animals

0:51:16.880 --> 0:51:20.480
<v Speaker 3>with remsleep, except for maybe the cuttlefish. That's so weird,

0:51:20.560 --> 0:51:24.240
<v Speaker 3>I know, I know, And not all mammals have sleep

0:51:24.440 --> 0:51:29.040
<v Speaker 3>really yeah, okay, so side note, remsleep evolved after non

0:51:29.080 --> 0:51:31.280
<v Speaker 3>remsleep as far as we can tell, and it's thought

0:51:31.320 --> 0:51:34.040
<v Speaker 3>to have emerged in mammals and birds independently.

0:51:34.200 --> 0:51:35.520
<v Speaker 6>Oh that's interesting.

0:51:35.760 --> 0:51:38.920
<v Speaker 3>Yeah, so, which indicates that it might be really important

0:51:38.920 --> 0:51:43.560
<v Speaker 3>for cognitive activities or warm bloodedness like aka and a thermy.

0:51:43.719 --> 0:51:47.919
<v Speaker 3>Oh interesting, Okay, cuttlefish, I don't know.

0:51:48.400 --> 0:51:49.720
<v Speaker 6>Cuttlefish are weird ones.

0:51:49.840 --> 0:51:54.880
<v Speaker 3>They are so cute. But if you do have remsleep,

0:51:54.920 --> 0:51:57.439
<v Speaker 3>you know how long are your sleep cycles between rem

0:51:57.480 --> 0:51:59.920
<v Speaker 3>and non rem. So, for instance, you said human is

0:52:00.120 --> 0:52:04.360
<v Speaker 3>ninety minutes, or so, the chinchilla is six minutes, six minutes.

0:52:04.800 --> 0:52:08.160
<v Speaker 6>They go through a whole six minutes. Yes, Oh my gosh,

0:52:08.400 --> 0:52:08.839
<v Speaker 6>you're like.

0:52:08.840 --> 0:52:14.520
<v Speaker 3>Done and up. There's also whether you sleep with all

0:52:14.560 --> 0:52:16.480
<v Speaker 3>of your brain or half of it.

0:52:16.560 --> 0:52:18.520
<v Speaker 4>That's I think one of my favorite facts I learned

0:52:18.560 --> 0:52:21.319
<v Speaker 4>in a children's book accidentally before we were It was

0:52:21.320 --> 0:52:24.040
<v Speaker 4>called sleepy, and that is where I learned about uni

0:52:24.080 --> 0:52:25.120
<v Speaker 4>hemispheric sleeping.

0:52:25.160 --> 0:52:28.560
<v Speaker 3>Hemispheric sleep Yep, it's a real thing, sleeping with one

0:52:28.560 --> 0:52:33.200
<v Speaker 3>eye open. It was a real thing. Aquatic mammals like whales, dolphins,

0:52:33.280 --> 0:52:35.839
<v Speaker 3>and seals, as well as some bird species, especially those

0:52:35.880 --> 0:52:38.279
<v Speaker 3>that are undergoing like long migrations, like.

0:52:38.200 --> 0:52:40.920
<v Speaker 4>The what's someone that never touches the land for albatross.

0:52:41.040 --> 0:52:41.719
<v Speaker 6>Yeah, is that it?

0:52:42.080 --> 0:52:48.920
<v Speaker 3>Oh gosh, I don't know. Sorry, sorry ornithologists, But yeah,

0:52:49.120 --> 0:52:52.719
<v Speaker 3>union hemispheric sleep. And we've got a little thing here

0:52:52.760 --> 0:52:54.719
<v Speaker 3>that shows like the eeg of what it looks like

0:52:54.840 --> 0:52:56.239
<v Speaker 3>when you have like once part of.

0:52:56.160 --> 0:52:57.719
<v Speaker 6>The part of your brain is on and part of

0:52:57.719 --> 0:52:59.560
<v Speaker 6>your brain is off. Yeah, Oh my gosh.

0:52:59.560 --> 0:53:04.360
<v Speaker 3>That's so it's interesting, amazing in the right and the left. Yeah.

0:53:04.400 --> 0:53:08.080
<v Speaker 3>And what's even weirder about this is that whales, dolphins,

0:53:08.080 --> 0:53:10.919
<v Speaker 3>and porpoises who do this union hemispheric sleep, they don't

0:53:10.920 --> 0:53:13.960
<v Speaker 3>seem to have rem sleep, or if they do, it's

0:53:14.040 --> 0:53:15.600
<v Speaker 3>not in a form that we recognize.

0:53:15.719 --> 0:53:17.200
<v Speaker 6>Oh that's so interesting.

0:53:17.320 --> 0:53:21.080
<v Speaker 3>Yeah. So it's like, did they lose remsleep right when

0:53:21.080 --> 0:53:24.080
<v Speaker 3>they went back to the oceans? Right, I don't know,

0:53:24.719 --> 0:53:27.840
<v Speaker 3>I don't know. Okay, but why do aquatic mammals sleep

0:53:27.840 --> 0:53:29.920
<v Speaker 3>with just one half of their brain? The mean a

0:53:29.960 --> 0:53:32.920
<v Speaker 3>few different possible reasons, right, So one is because they

0:53:32.920 --> 0:53:34.200
<v Speaker 3>need to breathe, right, and so they need to be

0:53:34.239 --> 0:53:36.160
<v Speaker 3>able to come up and have that more active thing.

0:53:36.320 --> 0:53:39.239
<v Speaker 3>Another is to reduce heat loss. Apparently it's supposed to

0:53:39.280 --> 0:53:41.600
<v Speaker 3>help with like thermogeneration.

0:53:41.000 --> 0:53:42.680
<v Speaker 6>Interesting, And a third is to be.

0:53:42.640 --> 0:53:44.759
<v Speaker 3>On the lookout for predators, and a fourth is to

0:53:45.600 --> 0:53:47.960
<v Speaker 3>stay close to one another because you can really drift

0:53:47.960 --> 0:53:51.600
<v Speaker 3>apart because if you're just drifting. Yeah, like if you've

0:53:51.600 --> 0:53:55.160
<v Speaker 3>seen those amazing videos of sperm whales all sleeping vertical

0:53:55.320 --> 0:53:59.200
<v Speaker 3>and like a like a forest of sperm whales. Yeah,

0:53:59.320 --> 0:54:02.040
<v Speaker 3>sea otters of course hold hands when they sleep, which

0:54:02.080 --> 0:54:07.319
<v Speaker 3>is just it's so cute pain sleep cute yep. And

0:54:07.520 --> 0:54:12.440
<v Speaker 3>unlike terrestrial mammals, newborn dolphins and orca whales are on

0:54:12.520 --> 0:54:15.760
<v Speaker 3>the move from the first moment. And unlike human babies,

0:54:15.800 --> 0:54:18.680
<v Speaker 3>which sleep, like you said so much, so randomly all

0:54:18.719 --> 0:54:22.560
<v Speaker 3>over the place, these baby dolphins and orca whales are

0:54:22.560 --> 0:54:25.920
<v Speaker 3>continuously active for like four weeks, like no sleep, you

0:54:25.920 --> 0:54:27.839
<v Speaker 3>don't sleep at all, no sleep along with mom.

0:54:27.880 --> 0:54:29.520
<v Speaker 6>Yeah, fascinating yep, yep.

0:54:29.840 --> 0:54:33.400
<v Speaker 3>And it's only after those weeks that sleep gradually returns.

0:54:33.760 --> 0:54:35.600
<v Speaker 3>And this might be because it's just a really vulnerable

0:54:35.600 --> 0:54:40.200
<v Speaker 3>time for those babies, it. Yeah. And even when sleeping,

0:54:40.400 --> 0:54:43.680
<v Speaker 3>these aquatic mammals are moving quite a bit. So dolphins

0:54:43.719 --> 0:54:46.960
<v Speaker 3>make counterclockwise circles regardless of which half of the brain is.

0:54:46.960 --> 0:54:49.080
<v Speaker 6>Sleeping counterclockwise circles.

0:54:49.920 --> 0:54:56.040
<v Speaker 3>Why, great question. I do not know. I do not know.

0:54:56.680 --> 0:54:59.680
<v Speaker 4>Counterclockwise circles regardless of which part of their brain is sleeping.

0:55:00.520 --> 0:55:04.799
<v Speaker 4>That is so interesting. I do they sleep? Sorry, I'm

0:55:04.800 --> 0:55:06.520
<v Speaker 4>gonna ask more details. Do they sleep?

0:55:06.600 --> 0:55:06.680
<v Speaker 2>Like?

0:55:06.760 --> 0:55:08.480
<v Speaker 4>Obviously it's one half at a time, but is it

0:55:08.600 --> 0:55:11.880
<v Speaker 4>like consolidated like at night time they're gonna like, okay,

0:55:12.040 --> 0:55:13.960
<v Speaker 4>forty minutes on this half and then forty minutes on

0:55:14.000 --> 0:55:14.680
<v Speaker 4>this half or whatever.

0:55:14.840 --> 0:55:15.160
<v Speaker 3>Question.

0:55:15.360 --> 0:55:15.799
<v Speaker 6>I don't know.

0:55:16.160 --> 0:55:16.600
<v Speaker 3>I don't know.

0:55:16.840 --> 0:55:18.239
<v Speaker 6>Okay, I'm so I can said.

0:55:18.280 --> 0:55:20.640
<v Speaker 3>There's a really great paper that I have I'll shout

0:55:20.640 --> 0:55:22.880
<v Speaker 3>out at the end that has like a lot more

0:55:22.960 --> 0:55:25.280
<v Speaker 3>information on this and even like pictures of dolphins sleeping

0:55:25.280 --> 0:55:28.760
<v Speaker 3>at the bottom of like enclosures and whales and stuff

0:55:28.800 --> 0:55:33.040
<v Speaker 3>like that. Yeah, yeah, okay. Fur seals listen to this description.

0:55:33.080 --> 0:55:33.920
<v Speaker 6>It's very cute.

0:55:34.160 --> 0:55:36.960
<v Speaker 3>When first seals sleep in water, they usually float on

0:55:37.000 --> 0:55:40.600
<v Speaker 3>their sides, holding one front and two hind flippers in

0:55:40.640 --> 0:55:44.280
<v Speaker 3>the air. The front flipper in the water constantly paddles

0:55:45.280 --> 0:55:47.160
<v Speaker 3>something cute, and the rest are just like up in

0:55:47.200 --> 0:55:51.400
<v Speaker 3>the air. One I always open and the other is closed. Wow.

0:55:52.920 --> 0:55:55.680
<v Speaker 3>Fur Seals also are one of these creatures that spend

0:55:55.719 --> 0:55:58.040
<v Speaker 3>some time on land and guess what their sleep is

0:55:58.080 --> 0:56:01.919
<v Speaker 3>like on land like a dog, like any other terrestrial mammal.

0:56:01.680 --> 0:56:04.400
<v Speaker 6>But when they're in the water they uni hemispheric.

0:56:04.080 --> 0:56:07.680
<v Speaker 3>Uni hemispheric sleep. What And when they're on land, both

0:56:07.680 --> 0:56:10.880
<v Speaker 3>eyes are closed and they cycle through REM and non rem.

0:56:11.000 --> 0:56:12.640
<v Speaker 6>But when they're in the water they don't.

0:56:12.719 --> 0:56:13.160
<v Speaker 3>Nope.

0:56:13.719 --> 0:56:16.360
<v Speaker 6>Oh that is so interesting, I know, I know.

0:56:17.440 --> 0:56:21.000
<v Speaker 3>Oh wow, it makes me like I never I mean,

0:56:21.040 --> 0:56:23.000
<v Speaker 3>I have like thought about sleep mostly in like a

0:56:23.080 --> 0:56:25.200
<v Speaker 3>very selfish like am I sleeping enough? Oh my gosh,

0:56:25.239 --> 0:56:28.680
<v Speaker 3>my sleep kind of away? But this is maybe more

0:56:28.719 --> 0:56:31.279
<v Speaker 3>interested in rem sleep than like ever.

0:56:31.600 --> 0:56:34.399
<v Speaker 6>Yeah yeah, same, Yeah, I did not know any of that.

0:56:34.680 --> 0:56:40.000
<v Speaker 3>Yep either. How interesting it's amazing. Yeah, okay, So, but

0:56:40.080 --> 0:56:43.400
<v Speaker 3>the fact that sleep comes in all shapes and sizes

0:56:43.440 --> 0:56:46.120
<v Speaker 3>across the animal kingdom and is even variable, like you said,

0:56:46.120 --> 0:56:49.120
<v Speaker 3>within an individual's life, it shows us that sleep is

0:56:49.160 --> 0:56:52.840
<v Speaker 3>not random, right, how species sleeps is the outcome of

0:56:52.960 --> 0:56:57.440
<v Speaker 3>millennia of adaptations. Nor is sleep rigid? Right? There may

0:56:57.480 --> 0:56:59.920
<v Speaker 3>be times when when we need to go with less sleep,

0:57:00.120 --> 0:57:04.080
<v Speaker 3>then we you know, ideally like to have migration, mid terms,

0:57:04.520 --> 0:57:11.680
<v Speaker 3>having a newborn, I love it, socializing stress. You know,

0:57:11.680 --> 0:57:13.920
<v Speaker 3>there's a lot of different reasons that might affect our

0:57:13.960 --> 0:57:17.360
<v Speaker 3>sleep duration, and we can do that, we can sleep

0:57:17.400 --> 0:57:19.200
<v Speaker 3>with we can have less sleep than we'd like for

0:57:19.560 --> 0:57:21.640
<v Speaker 3>a limited like a certain amount of time, and then

0:57:21.680 --> 0:57:24.800
<v Speaker 3>our bodies know to recover from.

0:57:24.600 --> 0:57:25.320
<v Speaker 6>That sleep debt.

0:57:26.120 --> 0:57:28.680
<v Speaker 3>So if the way that we sleep is not random,

0:57:29.240 --> 0:57:33.320
<v Speaker 3>what determines how species sleep? Why does a chinchilla have

0:57:33.360 --> 0:57:35.600
<v Speaker 3>a six minute that? I can't answer that. I don't

0:57:35.640 --> 0:57:37.800
<v Speaker 3>know about that, but it is. It is a great

0:57:37.840 --> 0:57:40.680
<v Speaker 3>question overall, and we don't exactly know. And so there

0:57:40.680 --> 0:57:43.720
<v Speaker 3>are some general patterns that I'll take you through. But

0:57:43.840 --> 0:57:47.880
<v Speaker 3>to every pattern there's an exceptions. So if we take

0:57:48.040 --> 0:57:50.920
<v Speaker 3>all that we know about sleep in animals and we

0:57:50.960 --> 0:57:54.400
<v Speaker 3>look for similarities after controlling for how related, they are

0:57:55.080 --> 0:58:02.240
<v Speaker 3>a few strong drivers emerge predation, metabolism, immune function, gestation, length,

0:58:02.880 --> 0:58:06.080
<v Speaker 3>brain mass, and neuroanatomical regions like the amygdala.

0:58:06.240 --> 0:58:08.200
<v Speaker 4>So these are all the parts of things that are

0:58:08.240 --> 0:58:11.800
<v Speaker 4>contributing to how long and how an animal is sleeping.

0:58:12.800 --> 0:58:16.840
<v Speaker 3>Mostly I would say, like how long and the polyphasic

0:58:16.920 --> 0:58:21.040
<v Speaker 3>versus got it? Yeah, yeah, monophasic, et cetera. Okay, And

0:58:21.880 --> 0:58:24.680
<v Speaker 3>I don't like there are some aspects of REM and

0:58:24.800 --> 0:58:27.600
<v Speaker 3>non REM, but like that, I mean, it's just like

0:58:27.640 --> 0:58:31.720
<v Speaker 3>it's really difficult to draw any sort of yeah, like parallels.

0:58:31.800 --> 0:58:33.680
<v Speaker 4>Well, and I feel like it's so interesting because one

0:58:33.680 --> 0:58:36.400
<v Speaker 4>of the books that I read it was like how

0:58:36.480 --> 0:58:39.280
<v Speaker 4>you define sleep in animals, Like with this behavioral thing

0:58:39.360 --> 0:58:42.840
<v Speaker 4>then also affects how we think about and look at.

0:58:42.720 --> 0:58:44.080
<v Speaker 6>The why of sleep.

0:58:44.200 --> 0:58:46.400
<v Speaker 4>Right, if you define it in slightly different ways, then

0:58:46.400 --> 0:58:48.200
<v Speaker 4>you might come to a different conclusion as to the

0:58:48.280 --> 0:58:49.400
<v Speaker 4>function of sleep.

0:58:49.560 --> 0:58:51.800
<v Speaker 3>It's a little bit of a guiding hypothesis, that's kind

0:58:51.800 --> 0:58:54.439
<v Speaker 3>of a thing. Yeah, and you're like, well, if if

0:58:54.520 --> 0:58:57.120
<v Speaker 3>REM is really the questions that you're asking are driving

0:58:57.160 --> 0:58:58.680
<v Speaker 3>that how you're looking.

0:58:58.440 --> 0:59:00.880
<v Speaker 4>For data, if you're only counting REM sleep as sleep,

0:59:00.960 --> 0:59:02.800
<v Speaker 4>then your conclusions are going to be totally different.

0:59:03.240 --> 0:59:05.360
<v Speaker 3>Or is more REM sleep better?

0:59:05.640 --> 0:59:05.800
<v Speaker 4>Right?

0:59:06.560 --> 0:59:07.880
<v Speaker 6>Yeah, it's so interesting.

0:59:07.880 --> 0:59:11.440
<v Speaker 3>It's really interesting. Okay, so let's talk about some of

0:59:11.480 --> 0:59:14.080
<v Speaker 3>these some of these different factors. When you're sleeping, you

0:59:14.120 --> 0:59:17.000
<v Speaker 3>are in a vulnerable state. Your senses are dulled, so

0:59:17.040 --> 0:59:20.120
<v Speaker 3>you can't hear that twig snap, and you're laying there motionless,

0:59:20.160 --> 0:59:22.920
<v Speaker 3>looking like a nice tasty snack for that tiger that's

0:59:23.000 --> 0:59:25.520
<v Speaker 3>you know, just caught your scent and creeping away from there,

0:59:25.840 --> 0:59:30.080
<v Speaker 3>creeping towards you. Actually creeping away would be great. So

0:59:30.120 --> 0:59:32.000
<v Speaker 3>you might be a little better off if you had

0:59:32.080 --> 0:59:34.440
<v Speaker 3>like a burrow or a tree hole to nestle into.

0:59:34.560 --> 0:59:36.760
<v Speaker 3>But if you just PLoP down in an exposed area,

0:59:37.440 --> 0:59:40.920
<v Speaker 3>you're you're playing a very risky, very risky game. Yeah,

0:59:40.960 --> 0:59:43.400
<v Speaker 3>and so to lower that risk, you might sleep less.

0:59:44.440 --> 0:59:47.320
<v Speaker 3>And that is what we tend to see. Prey species

0:59:47.480 --> 0:59:50.560
<v Speaker 3>or species that sleep in more vulnerable locations, like on

0:59:50.600 --> 0:59:52.920
<v Speaker 3>the ground, as opposed to like in the tree, they

0:59:52.960 --> 0:59:56.040
<v Speaker 3>tend to have shorter sleep durations. Interesting and in one experiment,

0:59:56.160 --> 0:59:59.560
<v Speaker 3>rats that encountered a predator got less sleep afterwards both

0:59:59.840 --> 1:00:02.640
<v Speaker 3>and they were like edge, you're just on edge. You

1:00:02.680 --> 1:00:04.720
<v Speaker 3>got to be like you're in lighter sleep. I guess

1:00:05.400 --> 1:00:09.040
<v Speaker 3>some research actually, some researchers actually suggest that light sleepers

1:00:09.080 --> 1:00:12.520
<v Speaker 3>and people with insomnia might have those predator or biting

1:00:12.600 --> 1:00:16.800
<v Speaker 3>insect vigilance mechanisms on overdrive. So if you're like someone

1:00:16.800 --> 1:00:20.000
<v Speaker 3>who is really hard time getting into like your wake

1:00:20.080 --> 1:00:22.960
<v Speaker 3>at the drop of it, like just a little rustle, yeah,

1:00:23.360 --> 1:00:27.280
<v Speaker 3>you might be. It's just it's adaptive, not anymore of

1:00:27.320 --> 1:00:30.960
<v Speaker 3>those you won't get eaten. It once was adaptive. Yeah,

1:00:31.000 --> 1:00:34.280
<v Speaker 3>and so sleeping in larger groups, like larger social groups,

1:00:34.320 --> 1:00:37.280
<v Speaker 3>that might help counteract them the vulnerability to predators while

1:00:37.280 --> 1:00:39.600
<v Speaker 3>you're sleeping. But then there's also the trade off of

1:00:39.680 --> 1:00:43.040
<v Speaker 3>social disturbances and parasite transmission.

1:00:42.520 --> 1:00:44.280
<v Speaker 6>Because you're just like alltogether.

1:00:44.840 --> 1:00:48.040
<v Speaker 3>Yeah, but so it's like sleep alone and be easier prey,

1:00:48.320 --> 1:00:50.640
<v Speaker 3>or sleep in a group and get less sleep, not

1:00:50.680 --> 1:00:53.680
<v Speaker 3>necessarily worse, but like, and maybe it's more efficient sleep,

1:00:53.680 --> 1:00:56.800
<v Speaker 3>but it does seem like sometimes it's shorter sleep okay. Interesting,

1:00:57.520 --> 1:01:00.880
<v Speaker 3>or you could sleep while your predators also sleep okay,

1:01:01.560 --> 1:01:04.560
<v Speaker 3>and predators tend to get more sleep just on average.

1:01:04.640 --> 1:01:08.360
<v Speaker 3>You're like, it's fine, bro right, Like I'm chilling. And

1:01:08.880 --> 1:01:11.240
<v Speaker 3>metabolism might also play a role in that when it

1:01:11.240 --> 1:01:15.240
<v Speaker 3>comes to predators versus prey because herbivores, which are more

1:01:15.320 --> 1:01:19.560
<v Speaker 3>generally more often prey, they need to eat more frequently

1:01:19.920 --> 1:01:23.120
<v Speaker 3>because they have faster metabolisms or like their food is

1:01:23.200 --> 1:01:26.160
<v Speaker 3>less calorically dense, and so they have to spend a

1:01:26.160 --> 1:01:29.400
<v Speaker 3>good chunk of their time foraging, especially if their food

1:01:29.640 --> 1:01:32.919
<v Speaker 3>is their preferred food is dispersed across the landscape, like, oh,

1:01:33.080 --> 1:01:34.600
<v Speaker 3>I have to get fruit trees, and I have to

1:01:34.640 --> 1:01:38.240
<v Speaker 3>go far to find them, and so you're like you're commute,

1:01:38.320 --> 1:01:39.280
<v Speaker 3>its long.

1:01:39.240 --> 1:01:39.560
<v Speaker 6>Got it?

1:01:39.600 --> 1:01:41.160
<v Speaker 3>And you're like, I got to get back to my

1:01:41.560 --> 1:01:42.240
<v Speaker 3>little burrow.

1:01:42.400 --> 1:01:42.640
<v Speaker 6>Yes.

1:01:43.440 --> 1:01:47.960
<v Speaker 3>Yeah. Animals with faster metabolisms relative to body size also

1:01:48.200 --> 1:01:51.600
<v Speaker 3>sleep less and smaller animals tend to sleep throughout the day.

1:01:51.600 --> 1:01:55.400
<v Speaker 3>They're polyphasic sleepers immune function, so we all know that

1:01:55.520 --> 1:01:58.760
<v Speaker 3>not getting enough sleep leaves us more vulnerable to infections,

1:01:58.960 --> 1:02:02.600
<v Speaker 3>and some studies us that species with longer sleep durations

1:02:02.720 --> 1:02:05.240
<v Speaker 3>have higher white blood cell counts and are less likely

1:02:05.320 --> 1:02:06.200
<v Speaker 3>to be parasitized.

1:02:06.560 --> 1:02:07.120
<v Speaker 6>Interesting.

1:02:07.600 --> 1:02:10.800
<v Speaker 3>I think this is a very big generality exactly.

1:02:11.080 --> 1:02:11.880
<v Speaker 6>Yeah.

1:02:11.920 --> 1:02:16.400
<v Speaker 3>And finally, oh, there's also gestation length. So longer gestations

1:02:16.440 --> 1:02:18.040
<v Speaker 3>are associated with shorter sleep.

1:02:18.280 --> 1:02:21.440
<v Speaker 4>So that's why, like elephants you said get only four hours. Yeah,

1:02:21.560 --> 1:02:24.960
<v Speaker 4>that's really weird though, why maybe it's just a correlation.

1:02:25.160 --> 1:02:29.640
<v Speaker 3>Yeah, it could be they're all metablet I don't. I mean,

1:02:29.640 --> 1:02:31.120
<v Speaker 3>that's like a lot, and this is like a very

1:02:31.200 --> 1:02:35.360
<v Speaker 3>much and I don't know episode how interesting though. And

1:02:35.400 --> 1:02:40.960
<v Speaker 3>then finally, bigger brains like body size. Yeah, and proportion

1:02:41.000 --> 1:02:43.440
<v Speaker 3>of body size equals a bigger chunk of time spent

1:02:43.520 --> 1:02:44.240
<v Speaker 3>in REM.

1:02:44.040 --> 1:02:45.720
<v Speaker 6>Sleep in REM sleep specifically.

1:02:45.920 --> 1:02:49.680
<v Speaker 3>Okay, but again this is all messy. So there was

1:02:49.720 --> 1:02:52.240
<v Speaker 3>a cool paper though I read that showed how vastly

1:02:52.240 --> 1:02:55.760
<v Speaker 3>different sleep could be for two closely related species and

1:02:56.240 --> 1:02:59.760
<v Speaker 3>how similar it could be for distantly related species. So,

1:02:59.800 --> 1:03:02.800
<v Speaker 3>for since the domestic cat and its relative the genet,

1:03:03.080 --> 1:03:04.960
<v Speaker 3>a cat gets around twelve and a half.

1:03:04.840 --> 1:03:06.800
<v Speaker 6>Hours of sleep, like I said a day with.

1:03:06.840 --> 1:03:09.760
<v Speaker 3>Three point two hours REM, and a genet gets about

1:03:09.800 --> 1:03:12.360
<v Speaker 3>half that six point three hours with one point three

1:03:12.360 --> 1:03:14.960
<v Speaker 3>hours RIM. And those are like closely related species.

1:03:15.080 --> 1:03:17.440
<v Speaker 4>Yeah yeah, and I is that just like because domestic

1:03:17.480 --> 1:03:19.160
<v Speaker 4>cats are just chillen.

1:03:19.120 --> 1:03:21.840
<v Speaker 3>They might be just domestic cats. Yeah. But then there's

1:03:21.880 --> 1:03:25.439
<v Speaker 3>also a golden mantled ground squirrel and a daegu, again

1:03:25.520 --> 1:03:29.600
<v Speaker 3>closely related. The squirrels fifteen point nine hours of sleep

1:03:29.840 --> 1:03:32.720
<v Speaker 3>with three in REM and seven point seven for the

1:03:32.800 --> 1:03:34.200
<v Speaker 3>daegu with point nine in REM.

1:03:34.280 --> 1:03:34.920
<v Speaker 6>How interesting.

1:03:34.920 --> 1:03:37.760
<v Speaker 3>So it's not just about like domestication, although I'm assuming

1:03:37.800 --> 1:03:39.400
<v Speaker 3>that is a decent part of it for the cat.

1:03:39.560 --> 1:03:39.760
<v Speaker 6>Yeah.

1:03:40.400 --> 1:03:43.880
<v Speaker 3>Then take a guinea pig in a baboon, not closely related,

1:03:44.080 --> 1:03:46.640
<v Speaker 3>but their sleep architecture is or they're not architecture, their

1:03:46.680 --> 1:03:51.400
<v Speaker 3>sleep like duration and REM proportion is very similar. They

1:03:51.400 --> 1:03:53.680
<v Speaker 3>each get about nine point four hours of sleep and

1:03:53.720 --> 1:03:54.360
<v Speaker 3>one of REM.

1:03:54.640 --> 1:03:55.960
<v Speaker 6>That's so interesting.

1:03:56.400 --> 1:03:59.240
<v Speaker 3>And in case you were wondering for humans humans, we

1:03:59.360 --> 1:04:01.720
<v Speaker 3>humans get the same amount of sleep as an Eastern

1:04:01.760 --> 1:04:07.840
<v Speaker 3>American mole. We get seven to eight hours and we

1:04:07.880 --> 1:04:10.880
<v Speaker 3>both have about two hours sleep REM. Oh, my gosh. Interesting,

1:04:11.040 --> 1:04:15.439
<v Speaker 3>that's funny. Yeah, it's really funny. But among primates though

1:04:15.560 --> 1:04:19.280
<v Speaker 3>humans are the exception, we are at the very extreme

1:04:19.520 --> 1:04:22.640
<v Speaker 3>end of sleep duration, with some of the shortest sleeps

1:04:22.720 --> 1:04:25.640
<v Speaker 3>of all primate species. The shortest sleeps.

1:04:25.680 --> 1:04:27.240
<v Speaker 4>Yeah, the shortest sleep of all primates.

1:04:27.280 --> 1:04:29.080
<v Speaker 6>Yep, huh yeah.

1:04:29.120 --> 1:04:32.720
<v Speaker 3>On the other end of the spectrum are owl or

1:04:32.800 --> 1:04:35.520
<v Speaker 3>night monkeys owl monkeys or night monkeys, which sleep about

1:04:35.520 --> 1:04:38.600
<v Speaker 3>seventeen hours, but they get the same amount of REM

1:04:38.680 --> 1:04:39.520
<v Speaker 3>sleep as humans.

1:04:40.520 --> 1:04:43.320
<v Speaker 6>That is so interesting. Yeah, oh, I do want to

1:04:43.320 --> 1:04:45.720
<v Speaker 6>look so much more into REM now. I know, right,

1:04:46.880 --> 1:04:48.040
<v Speaker 6>what is up with that?

1:04:49.360 --> 1:04:52.600
<v Speaker 3>I know what is up with that sleep?

1:04:52.640 --> 1:04:53.440
<v Speaker 6>What is up with that?

1:04:54.440 --> 1:04:58.200
<v Speaker 3>Based on our human body size, body or brain size,

1:04:58.240 --> 1:05:02.680
<v Speaker 3>body mass, predation, risks, foraging needs, sexual selection, dynamics, diet,

1:05:02.720 --> 1:05:05.240
<v Speaker 3>and what we know about other primates like researchers have

1:05:05.320 --> 1:05:07.880
<v Speaker 3>kind of compiled this model to be like, how should

1:05:07.880 --> 1:05:10.600
<v Speaker 3>we how should we expect humans to sleep based on

1:05:10.640 --> 1:05:13.200
<v Speaker 3>what we know about all other primates? And that comes

1:05:13.200 --> 1:05:14.800
<v Speaker 3>out to nine and a half hours a night.

1:05:14.880 --> 1:05:16.920
<v Speaker 4>That's how much we should be getting housted.

1:05:17.000 --> 1:05:19.720
<v Speaker 3>Based on these that is not and but we on

1:05:19.760 --> 1:05:22.920
<v Speaker 3>average it's six to seven hours for humans. And this

1:05:22.960 --> 1:05:24.760
<v Speaker 3>does not mean that we should all be sleeping nine.

1:05:24.680 --> 1:05:25.480
<v Speaker 6>And a half hours.

1:05:25.560 --> 1:05:28.680
<v Speaker 3>It's just what the model predicts based on other primates.

1:05:28.680 --> 1:05:30.400
<v Speaker 4>So it shows that we are weirdos.

1:05:30.640 --> 1:05:33.960
<v Speaker 3>Yes, because evidence, I mean, evidence points to six to

1:05:34.000 --> 1:05:36.320
<v Speaker 3>seven is normal sleep or six to eight is normal

1:05:36.360 --> 1:05:38.680
<v Speaker 3>sleep in humans. And it might just be that we

1:05:38.760 --> 1:05:41.840
<v Speaker 3>somehow squeezed our sleep into a shorter duration, like we're

1:05:41.840 --> 1:05:46.360
<v Speaker 3>more efficient or intense sleepers. Other grade apes sleep a

1:05:46.360 --> 1:05:48.960
<v Speaker 3>bit more than humans, but less than like night out

1:05:49.040 --> 1:05:52.520
<v Speaker 3>or night monkeys and like chimpanzees get about ten hours

1:05:52.600 --> 1:05:55.600
<v Speaker 3>with similar rem as humans, and gorilla sleep about twelve,

1:05:55.720 --> 1:06:00.320
<v Speaker 3>orangutangs sleep about nine, slightly rest less than humans. But

1:06:01.280 --> 1:06:05.680
<v Speaker 3>when it comes to humans and other great apes, we

1:06:05.760 --> 1:06:09.520
<v Speaker 3>do share other characteristics. So we have this high proportion

1:06:09.600 --> 1:06:13.240
<v Speaker 3>of rem sleep and we have nesting behavior, which I

1:06:13.520 --> 1:06:18.080
<v Speaker 3>just think is adorable. Many of the over four hundred

1:06:18.160 --> 1:06:21.640
<v Speaker 3>primate species that exist sleep in trees, whether that's in

1:06:21.680 --> 1:06:25.760
<v Speaker 3>tree holes or on bear branches, just like balancing up there.

1:06:26.480 --> 1:06:28.840
<v Speaker 3>Even if they spend like much of their waking time

1:06:28.960 --> 1:06:33.200
<v Speaker 3>on the ground, they will sleep in the trees. And

1:06:33.240 --> 1:06:36.560
<v Speaker 3>this might help with like predator avoidance. Probably other species

1:06:36.640 --> 1:06:39.040
<v Speaker 3>might sleep individually, or they might sleep in groups, or

1:06:39.120 --> 1:06:42.120
<v Speaker 3>they might sleep on bare ground or on cliffs, like

1:06:42.160 --> 1:06:45.360
<v Speaker 3>baboons sleep on cliffs and on bare grounds. And some

1:06:45.680 --> 1:06:50.240
<v Speaker 3>build nests mostly in trees. In fact, all great apes

1:06:50.320 --> 1:06:51.760
<v Speaker 3>build nests, all of them.

1:06:51.880 --> 1:06:52.640
<v Speaker 6>I did not know that.

1:06:52.960 --> 1:06:55.200
<v Speaker 3>Yeah, me either. Yeah, And so this suggests that the

1:06:55.240 --> 1:06:59.000
<v Speaker 3>behavior emerged about fourteen to eighteen million years ago. Interesting,

1:06:59.360 --> 1:07:02.959
<v Speaker 3>they are built individually, they take between one to seven

1:07:03.080 --> 1:07:06.800
<v Speaker 3>minutes to construct, and they're usually built every night with

1:07:07.200 --> 1:07:08.240
<v Speaker 3>occasional reuse.

1:07:08.440 --> 1:07:10.160
<v Speaker 6>So they just make their own new nests.

1:07:10.160 --> 1:07:11.840
<v Speaker 3>To make their own new nest, yeah, with a bunch

1:07:11.840 --> 1:07:14.600
<v Speaker 3>of different materials. It's there is so much more about

1:07:14.600 --> 1:07:17.200
<v Speaker 3>nest building. And I have a paper too, and so

1:07:17.640 --> 1:07:20.280
<v Speaker 3>why did we start to build nests. It's thought that

1:07:20.400 --> 1:07:23.560
<v Speaker 3>as body size got bigger in these great ape species,

1:07:23.960 --> 1:07:26.760
<v Speaker 3>they probably helped to make sleeping more comfortable overall and

1:07:26.840 --> 1:07:29.320
<v Speaker 3>to protect against damage. If you like fell out of

1:07:29.320 --> 1:07:31.040
<v Speaker 3>a tree, then like your body.

1:07:30.880 --> 1:07:32.760
<v Speaker 6>Was just like a little cushion.

1:07:32.840 --> 1:07:35.280
<v Speaker 3>You've got some cushions, so like you're yeah, it makes

1:07:35.280 --> 1:07:40.120
<v Speaker 3>it more comfortable. And so this also helped to avoid predation.

1:07:40.440 --> 1:07:44.080
<v Speaker 3>So research suggests that chimpanzees build nests higher and in

1:07:44.160 --> 1:07:46.720
<v Speaker 3>closer proximity to each other in places when there are

1:07:46.760 --> 1:07:50.720
<v Speaker 3>where there are more predators. Ah, and also thermal regulation,

1:07:50.880 --> 1:07:52.960
<v Speaker 3>so you can decide, Okay, is your nest placement going

1:07:53.040 --> 1:07:54.880
<v Speaker 3>to be higher up or lower down? Do I need

1:07:54.920 --> 1:07:57.120
<v Speaker 3>more insulation? Do I need to pack in some more leaves,

1:07:57.400 --> 1:07:59.760
<v Speaker 3>keep chilli night? Is it nice and warm? You know,

1:07:59.840 --> 1:08:01.480
<v Speaker 3>like I want to get a breeze up in there.

1:08:02.280 --> 1:08:05.560
<v Speaker 3>And finally, nests may also help to deter biting insects.

1:08:05.800 --> 1:08:09.280
<v Speaker 3>So researchers found that some orangutanks built their nests near

1:08:09.400 --> 1:08:13.959
<v Speaker 3>naturally mosquito repellent tree species when mosquitoes were abundant.

1:08:14.240 --> 1:08:16.200
<v Speaker 6>I love this so much, I know.

1:08:17.760 --> 1:08:19.320
<v Speaker 3>I mean, if you think about nest building is an

1:08:19.360 --> 1:08:22.760
<v Speaker 3>incredible behavior and there are some researchers that categorize it

1:08:22.840 --> 1:08:25.520
<v Speaker 3>under tool use, which would make it the most pervasive

1:08:25.640 --> 1:08:30.680
<v Speaker 3>among great apes. Wow, yeah, it's environmental problem solving when

1:08:30.680 --> 1:08:34.000
<v Speaker 3>it comes down to it. Did great apes build nests

1:08:34.120 --> 1:08:38.479
<v Speaker 3>because they were smart? Or did building nests help make

1:08:38.640 --> 1:08:43.479
<v Speaker 3>evolve smartness evolve enhanced cognition in Elisha, yeah, chicken or egg?

1:08:43.560 --> 1:08:43.920
<v Speaker 3>I don't know.

1:08:44.000 --> 1:08:44.600
<v Speaker 6>Yeah, I don't know.

1:08:45.400 --> 1:08:47.519
<v Speaker 3>But so, like I mentioned, most of these nests are

1:08:47.520 --> 1:08:50.439
<v Speaker 3>in trees. But humans have long slept on the ground,

1:08:50.640 --> 1:08:53.760
<v Speaker 3>despite the ground making us more vulnerable to predators, and

1:08:53.960 --> 1:08:57.599
<v Speaker 3>some researchers have suggested that this ground sleeping, with its

1:08:57.680 --> 1:09:01.880
<v Speaker 3>more stable surface, would have enabled even deeper sleep, which

1:09:01.920 --> 1:09:06.960
<v Speaker 3>then allowed us to sleep more intensely fall right, we

1:09:07.000 --> 1:09:10.000
<v Speaker 3>don't have to have that increased vigilance as much, and

1:09:10.080 --> 1:09:12.639
<v Speaker 3>so that's what maybe allowed us to shorten our sleep duration.

1:09:13.080 --> 1:09:16.639
<v Speaker 3>And then once humans developed the ability to control fire,

1:09:17.200 --> 1:09:19.320
<v Speaker 3>that would have cut down on the risk of predators

1:09:19.479 --> 1:09:22.560
<v Speaker 3>and biting insects, and it would have increased our thermoregulation

1:09:22.680 --> 1:09:27.439
<v Speaker 3>capacities while allowing us longer hours to socialize into the night,

1:09:27.720 --> 1:09:33.080
<v Speaker 3>exchanging ideas and storytelling, maybe even promoting the evolution of language.

1:09:33.320 --> 1:09:36.800
<v Speaker 3>And so in short, sleeping on the ground helped to

1:09:36.840 --> 1:09:44.479
<v Speaker 3>make us become human. Oh right, once we made it

1:09:44.520 --> 1:09:48.240
<v Speaker 3>there on the ground. What happened then? Did we just

1:09:48.280 --> 1:09:50.479
<v Speaker 3>stick to our six to eight hours a night with

1:09:50.680 --> 1:09:55.120
<v Speaker 3>no breaks? Or is the story slightly more complicated than that.

1:09:56.400 --> 1:09:58.360
<v Speaker 3>I'm leaving you on a cliffhanger, so you'll have to

1:09:58.400 --> 1:10:00.720
<v Speaker 3>tune in next week to find out. But I hope

1:10:00.760 --> 1:10:03.679
<v Speaker 3>you liked this little hodgepodge of a tour through animal

1:10:03.960 --> 1:10:05.040
<v Speaker 3>kingdom sleep.

1:10:05.200 --> 1:10:06.280
<v Speaker 6>I loved it.

1:10:06.280 --> 1:10:08.479
<v Speaker 3>It's not a mistake. No, sleep is not a.

1:10:08.520 --> 1:10:10.839
<v Speaker 6>Mistake, not an evolutionary mistake.

1:10:11.160 --> 1:10:13.839
<v Speaker 3>I think that was mostly said tongue and totally sounded

1:10:13.880 --> 1:10:14.080
<v Speaker 3>like it.

1:10:14.560 --> 1:10:16.000
<v Speaker 2>Yeah.

1:10:16.080 --> 1:10:18.240
<v Speaker 4>Oh that was really fun and it made me really

1:10:18.280 --> 1:10:20.960
<v Speaker 4>excited to find out what humans did with our sleep.

1:10:21.160 --> 1:10:22.559
<v Speaker 3>I can't wait to tellt you.

1:10:23.120 --> 1:10:24.360
<v Speaker 6>I mean, I don't sleep on the floor.

1:10:25.040 --> 1:10:26.680
<v Speaker 3>I don't sleep on the floor. I have slept on

1:10:26.800 --> 1:10:30.599
<v Speaker 3>floors many times, or on preferred benches. It's horrible.

1:10:32.360 --> 1:10:34.200
<v Speaker 4>So I can't wait to hear what we did when sleep.

1:10:35.840 --> 1:10:36.040
<v Speaker 6>Well.

1:10:36.080 --> 1:10:40.360
<v Speaker 3>In the meantime, there's a lot more reading. You shall

1:10:40.360 --> 1:10:42.000
<v Speaker 3>we tell the people where to read?

1:10:42.160 --> 1:10:43.360
<v Speaker 6>Let us okay, I tell them.

1:10:43.880 --> 1:10:47.320
<v Speaker 3>I have many sources, many sources for this one, because

1:10:47.320 --> 1:10:48.760
<v Speaker 3>I just kept going down rabbit holes.

1:10:48.840 --> 1:10:51.840
<v Speaker 6>I loved them all. We didn't even talk about rabbitsleep, didn't.

1:10:52.840 --> 1:10:54.720
<v Speaker 3>I actually did have a section where I was I

1:10:54.800 --> 1:10:58.320
<v Speaker 3>went through each of the animals on my jas to

1:10:58.360 --> 1:11:01.719
<v Speaker 3>be like, raccoon sleep, this amount, possum sleep, this amount,

1:11:01.800 --> 1:11:04.200
<v Speaker 3>my favorite animal besides the Tasmanian douvile.

1:11:04.200 --> 1:11:05.120
<v Speaker 6>Squirrels, et cetera.

1:11:05.240 --> 1:11:06.960
<v Speaker 3>And I cut it because I was like much, it's

1:11:06.960 --> 1:11:12.040
<v Speaker 3>way too many animals. Okay, you can find more information.

1:11:12.720 --> 1:11:15.599
<v Speaker 3>There's a book about a lot of animal sleep called

1:11:15.640 --> 1:11:20.240
<v Speaker 3>Evolution of Sleep, Phylogenetic and Functional Perspectives by McNamara at

1:11:20.280 --> 1:11:23.479
<v Speaker 3>all from twenty ten. Then there's a great paper I

1:11:23.479 --> 1:11:26.200
<v Speaker 3>loved from two thousand and eight called Unearthing the Phylogenetic

1:11:26.320 --> 1:11:29.920
<v Speaker 3>Roots of Sleep by Aladda and Seagull from two thousand

1:11:29.960 --> 1:11:31.439
<v Speaker 3>and eight. I think I already said two thousand and

1:11:31.439 --> 1:11:35.719
<v Speaker 3>eight multiple times by liaman at All from two thousand

1:11:35.760 --> 1:11:38.720
<v Speaker 3>and eight as well Cetacean Sleep, An Unusual Form of

1:11:38.720 --> 1:11:42.200
<v Speaker 3>Mammalian Sleep, and finally by Fruth and Stewart, Sleep and

1:11:42.280 --> 1:11:44.519
<v Speaker 3>Nesting Behavior in Primates a review.

1:11:45.280 --> 1:11:48.719
<v Speaker 6>Love it, great stuff. I had.

1:11:48.880 --> 1:11:51.439
<v Speaker 4>Most of this information that I shared came from a

1:11:51.479 --> 1:11:54.880
<v Speaker 4>book from twenty twelve that was called sleep a very

1:11:54.920 --> 1:11:59.920
<v Speaker 4>short introduction from Oxford University Press. It covers all the

1:12:01.320 --> 1:12:04.519
<v Speaker 4>But I also enjoyed a paper from Physiological Reviews from

1:12:04.520 --> 1:12:07.360
<v Speaker 4>also twenty twelve that's weird, that was called control of

1:12:07.360 --> 1:12:09.640
<v Speaker 4>Sleep and Wakefulness by Brown at All. And then the

1:12:09.680 --> 1:12:15.760
<v Speaker 4>paper that was not funded by industry about the wearable

1:12:15.800 --> 1:12:19.719
<v Speaker 4>finger tracker ring sleep measures was from Scientific Reports published

1:12:19.720 --> 1:12:20.880
<v Speaker 4>this year twenty twenty five.

1:12:21.160 --> 1:12:22.880
<v Speaker 3>Trying so hard not to say any brand name.

1:12:23.000 --> 1:12:25.000
<v Speaker 6>I know you know the ones.

1:12:26.520 --> 1:12:28.559
<v Speaker 4>I guess twenty twenty five is last year by the

1:12:28.560 --> 1:12:30.880
<v Speaker 4>time this comes out, doesn't matter anyways. It was by

1:12:31.080 --> 1:12:34.400
<v Speaker 4>Herberger at all and it was titled performance of Wearable

1:12:34.439 --> 1:12:38.000
<v Speaker 4>finger ring Trackers for diagnostic sleep measurement in the clinical context.

1:12:38.160 --> 1:12:39.680
<v Speaker 4>But I have other ones as well to you, and

1:12:39.760 --> 1:12:41.599
<v Speaker 4>so many more papers, so you can read them all

1:12:41.640 --> 1:12:43.719
<v Speaker 4>and find them all on our website.

1:12:43.720 --> 1:12:45.839
<v Speaker 6>This podcast will kill you dot com.

1:12:46.040 --> 1:12:50.080
<v Speaker 3>We will post them all there. Stephen Ray Morris, thank

1:12:50.120 --> 1:12:53.920
<v Speaker 3>you again, what an absolute delight. It was, really, Thank

1:12:53.920 --> 1:12:56.280
<v Speaker 3>you so much for sharing your story. Also, sorry that

1:12:56.320 --> 1:12:58.840
<v Speaker 3>you've had sleep proless. No we're not saying your sleep press.

1:12:58.880 --> 1:12:59.479
<v Speaker 6>This was a delight.

1:12:59.720 --> 1:13:02.920
<v Speaker 3>No hearing your voice. Hearing your sharing your story, it

1:13:02.920 --> 1:13:05.640
<v Speaker 3>was wonderful. Thank you and thank you also to Bloodmobile

1:13:05.680 --> 1:13:07.479
<v Speaker 3>for preventing the music for this episode, in all of

1:13:07.479 --> 1:13:08.519
<v Speaker 3>our episodes, thank.

1:13:08.400 --> 1:13:09.000
<v Speaker 6>You, thank you.

1:13:09.040 --> 1:13:12.720
<v Speaker 4>Thank you to everyone here and Exactly Right Studios, as

1:13:12.760 --> 1:13:15.120
<v Speaker 4>well as everyone who helps make this podcast possible.

1:13:15.360 --> 1:13:20.000
<v Speaker 3>Yes, including you listeners. Thank you for listening, patrons. Thank

1:13:20.040 --> 1:13:22.360
<v Speaker 3>you for patroning your patrons.

1:13:22.800 --> 1:13:23.200
<v Speaker 6>Patrons.

1:13:25.560 --> 1:13:27.799
<v Speaker 3>Yeah, thank you for everythank you.

1:13:27.840 --> 1:13:28.240
<v Speaker 6>Wow.

1:13:28.960 --> 1:13:31.439
<v Speaker 3>Until next time, wash your hands animals

1:13:37.560 --> 1:13:37.600
<v Speaker 2>A