1 00:00:02,600 --> 00:00:15,919 Speaker 1: Bloomberg Audio Studios, Podcasts, Radio News. 2 00:00:18,000 --> 00:00:21,240 Speaker 2: Hello and welcome to another episode of the Odd Lots podcast. 3 00:00:21,320 --> 00:00:22,880 Speaker 2: I'm Tracy Alloway and I'm Joe. 4 00:00:22,920 --> 00:00:24,000 Speaker 3: Why isn't thal Joe? 5 00:00:24,040 --> 00:00:25,320 Speaker 2: Do you know much about MODERNA? 6 00:00:26,480 --> 00:00:27,360 Speaker 4: Well, I had. 7 00:00:27,280 --> 00:00:29,920 Speaker 3: Heard the name for maybe a few years, and then 8 00:00:29,960 --> 00:00:33,680 Speaker 3: they became household name some point in twenty twenty when 9 00:00:33,840 --> 00:00:36,919 Speaker 3: they were ahead of the race to develop a COVID vaccine. 10 00:00:37,400 --> 00:00:40,720 Speaker 3: Then it became massive, and then I don't know much 11 00:00:40,760 --> 00:00:41,159 Speaker 3: beyond that. 12 00:00:41,600 --> 00:00:43,519 Speaker 2: Yeah, for me, this is a company that kind of 13 00:00:43,600 --> 00:00:46,599 Speaker 2: came out of nowhere during the pandemic, and as you're right, 14 00:00:46,640 --> 00:00:50,720 Speaker 2: it kind of shot into household name territory. Here's my 15 00:00:50,760 --> 00:00:53,320 Speaker 2: other question. Do you know what a CFO does? 16 00:00:54,760 --> 00:00:54,840 Speaker 5: What? 17 00:00:55,040 --> 00:00:58,680 Speaker 3: That is a great question, actually, because I mean, I 18 00:00:58,680 --> 00:01:02,720 Speaker 3: guess I would say yes in this sense that I 19 00:01:02,800 --> 00:01:06,840 Speaker 3: think they're the ones who are sort of watching the financing, 20 00:01:07,480 --> 00:01:11,679 Speaker 3: helping to make capital allocation decisions, although I imagine that 21 00:01:11,760 --> 00:01:15,280 Speaker 3: the CEO also has that. I think the CFO is 22 00:01:15,319 --> 00:01:19,800 Speaker 3: the one primarily involved in putting together the earnings and 23 00:01:20,120 --> 00:01:23,560 Speaker 3: you know, communicating the finance side, specifically the analyst. But 24 00:01:24,040 --> 00:01:26,399 Speaker 3: I guess I only partly know what a CFO does 25 00:01:26,640 --> 00:01:26,880 Speaker 3: to me. 26 00:01:27,080 --> 00:01:29,399 Speaker 2: The thing I always think when I hear CFO I 27 00:01:29,400 --> 00:01:32,640 Speaker 2: always think they're the hard ones. Sorry, They're the ones 28 00:01:32,760 --> 00:01:36,600 Speaker 2: that answer the hard questions on the on the earnings calls. 29 00:01:36,800 --> 00:01:37,600 Speaker 2: That's what they do. 30 00:01:38,120 --> 00:01:40,400 Speaker 4: I love that. I think that, yes, that's right. 31 00:01:40,440 --> 00:01:42,440 Speaker 3: The CEO is like, oh, we get to these great 32 00:01:42,480 --> 00:01:44,920 Speaker 3: products and blah blah. And then like someone asked a 33 00:01:44,959 --> 00:01:48,080 Speaker 3: really technical question about like well if your borrow will 34 00:01:48,120 --> 00:01:50,160 Speaker 3: get this above so far and margins and they're like, 35 00:01:50,200 --> 00:01:51,760 Speaker 3: I'm going to bring the CFO in the answer this. 36 00:01:51,880 --> 00:01:55,840 Speaker 2: Then yeah, exactly. Well, I'm pleased to say today we do, 37 00:01:55,960 --> 00:01:58,960 Speaker 2: in fact have the perfect guest to answer the question 38 00:01:59,120 --> 00:02:01,640 Speaker 2: of what is modern and also what does a CFO 39 00:02:01,840 --> 00:02:04,440 Speaker 2: actually do. We are going to be speaking to the 40 00:02:04,440 --> 00:02:08,040 Speaker 2: CFO of MODERNA, Jamie Mack. Jamie, thank you so much 41 00:02:08,040 --> 00:02:09,240 Speaker 2: for coming on on thoughts. 42 00:02:09,480 --> 00:02:12,240 Speaker 5: Hi, Tracy and Joe, thank you for having me. It's 43 00:02:12,240 --> 00:02:13,320 Speaker 5: a pleasure to be here with you. 44 00:02:13,919 --> 00:02:16,200 Speaker 2: So maybe just to begin, can you give us the 45 00:02:16,480 --> 00:02:19,840 Speaker 2: sort of elevator pitch summary of what it is that 46 00:02:19,960 --> 00:02:23,640 Speaker 2: MODERNA does and full disclosure, I was in Hong Kong 47 00:02:23,760 --> 00:02:27,080 Speaker 2: for a few years of the pandemic, so I missed 48 00:02:27,200 --> 00:02:30,720 Speaker 2: a lot of the vaccine conversation here in the US. 49 00:02:30,800 --> 00:02:33,720 Speaker 2: There was a very different vaccine conversation that was happening 50 00:02:33,720 --> 00:02:36,200 Speaker 2: in Hong Kong and in mainland China at the time. 51 00:02:36,639 --> 00:02:39,360 Speaker 2: But what is it that you actually do and how 52 00:02:39,480 --> 00:02:42,280 Speaker 2: is it that you have become a household name in 53 00:02:42,320 --> 00:02:44,200 Speaker 2: a relatively few short years. 54 00:02:44,400 --> 00:02:48,160 Speaker 5: Well sure, so, first I found your introduction quite entertaining. 55 00:02:49,440 --> 00:02:53,560 Speaker 5: The CFO actually in our business because we are very 56 00:02:53,639 --> 00:02:55,720 Speaker 5: much a science business, which I'll get into. 57 00:02:55,960 --> 00:02:58,000 Speaker 4: It's actually our president and CEO. 58 00:02:57,760 --> 00:03:00,160 Speaker 5: That get the really tough questions. But I get to 59 00:03:00,760 --> 00:03:02,560 Speaker 5: my own share as well, which we can get into. 60 00:03:02,639 --> 00:03:06,560 Speaker 3: But the CEO has to answer the tough biology questions. 61 00:03:07,639 --> 00:03:10,560 Speaker 4: Well, he's quite good at it. He's he was part 62 00:03:10,600 --> 00:03:12,720 Speaker 4: you employee number one and. 63 00:03:13,000 --> 00:03:15,120 Speaker 5: Has been here and built this business for thirteen years 64 00:03:15,160 --> 00:03:19,080 Speaker 5: so and he's got a science background, so he's quite 65 00:03:19,080 --> 00:03:21,440 Speaker 5: good at it. And then our president, Stephen Hoague is 66 00:03:21,520 --> 00:03:24,919 Speaker 5: a doctor by trade, so obviously they answered most of 67 00:03:24,960 --> 00:03:25,960 Speaker 5: the scientific questions. 68 00:03:25,960 --> 00:03:28,800 Speaker 4: But so Maderna is obviously known. 69 00:03:28,720 --> 00:03:31,760 Speaker 5: Due to how we help the global community with COVID, 70 00:03:32,320 --> 00:03:34,320 Speaker 5: but it's really much more than that. It is a 71 00:03:34,360 --> 00:03:38,840 Speaker 5: platform company revolving around MR and a which really makes 72 00:03:38,880 --> 00:03:42,160 Speaker 5: the proteins in a body, and those proteins can help 73 00:03:42,240 --> 00:03:46,040 Speaker 5: either fight infectious diseases and prevent against any kind of 74 00:03:46,360 --> 00:03:49,680 Speaker 5: infectious disease, or be a therapy, and we can get 75 00:03:49,680 --> 00:03:51,440 Speaker 5: into the segments that we're in, but it can be 76 00:03:51,440 --> 00:03:53,920 Speaker 5: in oncology, it can be a rare disease. And we 77 00:03:54,000 --> 00:03:56,440 Speaker 5: actually believed, and that was the principal belief in the 78 00:03:56,440 --> 00:03:59,680 Speaker 5: company is if this platform can work, it's going to 79 00:03:59,720 --> 00:04:02,720 Speaker 5: be able. Since it's part of your natural body, it's 80 00:04:02,760 --> 00:04:05,680 Speaker 5: going to be able to help solve many different therapeutic 81 00:04:05,760 --> 00:04:07,200 Speaker 5: areas in the body. 82 00:04:07,720 --> 00:04:09,240 Speaker 4: And so that's a little bit about Maderna. 83 00:04:09,480 --> 00:04:12,800 Speaker 5: In over the last thirteen years, we've built a pipeline 84 00:04:12,840 --> 00:04:16,760 Speaker 5: of forty five drug candidates. Obviously we're known for covid, 85 00:04:16,880 --> 00:04:19,359 Speaker 5: but also in other respiratory diseases. We hope to launch 86 00:04:19,360 --> 00:04:22,800 Speaker 5: our second drug this year, RSV, which became pretty well 87 00:04:22,839 --> 00:04:26,239 Speaker 5: known last year as it had a pretty significant spike, 88 00:04:26,640 --> 00:04:30,040 Speaker 5: but also in flu and other respiratory diseases. And then 89 00:04:30,120 --> 00:04:33,520 Speaker 5: in oncology we've got an exciting cancer therapy that we 90 00:04:33,560 --> 00:04:36,800 Speaker 5: are excited about rare diseases and other latent diseases. So 91 00:04:36,800 --> 00:04:38,680 Speaker 5: that's a little bit about Maderna. We've been around since 92 00:04:38,680 --> 00:04:43,160 Speaker 5: twenty eleven. We've got almost six thousand employees. We're based 93 00:04:43,160 --> 00:04:45,240 Speaker 5: out of Cambridge, Massachusetts, but have. 94 00:04:45,400 --> 00:04:48,599 Speaker 4: Some facilities all across the globe, and we've got quite 95 00:04:48,640 --> 00:04:51,400 Speaker 4: an exciting pipeline ahead of us. That was excellent. 96 00:04:51,400 --> 00:04:55,320 Speaker 3: All right, Now, what does the CFO or you specifically? 97 00:04:55,360 --> 00:04:57,919 Speaker 3: What is your job within the company? 98 00:04:58,200 --> 00:05:01,720 Speaker 5: So my CFO role is really not that different than 99 00:05:01,839 --> 00:05:04,640 Speaker 5: many other CFOs. It's just you know, in a different space. 100 00:05:04,680 --> 00:05:08,720 Speaker 5: And I think there's principally four different areas. One is 101 00:05:09,400 --> 00:05:13,360 Speaker 5: the foundation, which is controllership, so that's accurate books and records. 102 00:05:13,400 --> 00:05:16,800 Speaker 5: That's safeguarding our assets, and that's got to be foundational and. 103 00:05:16,760 --> 00:05:17,679 Speaker 4: An absolute given. 104 00:05:17,880 --> 00:05:20,640 Speaker 5: The second is allocating capital, and we can talk about 105 00:05:20,640 --> 00:05:22,760 Speaker 5: that some more, but what is the envelope where we 106 00:05:22,839 --> 00:05:25,840 Speaker 5: going to spend it? How much goes into our investment 107 00:05:25,920 --> 00:05:28,400 Speaker 5: in our R and D pipeline, how much goes into capital. 108 00:05:28,080 --> 00:05:29,520 Speaker 4: Expenditure and S G and A. 109 00:05:30,440 --> 00:05:33,200 Speaker 5: The third is to support decision making across the company 110 00:05:33,480 --> 00:05:36,960 Speaker 5: and train our teams to understand how to measure return 111 00:05:37,000 --> 00:05:40,600 Speaker 5: on investment and how to think through decisions that are 112 00:05:40,600 --> 00:05:43,320 Speaker 5: made every single day, thousands of decisions across the company 113 00:05:43,360 --> 00:05:46,120 Speaker 5: every single day. And then the last is stakeholder management 114 00:05:46,320 --> 00:05:52,800 Speaker 5: and with whether it's investors, employees, the board of directors, customers, partners, suppliers. 115 00:05:53,279 --> 00:05:53,440 Speaker 4: You know. 116 00:05:53,440 --> 00:05:55,240 Speaker 5: That's how I think about it, which really isn't too 117 00:05:55,279 --> 00:05:57,599 Speaker 5: different from my prior role. Is it's a CFO of 118 00:05:57,600 --> 00:06:00,919 Speaker 5: a different company or in my opinion, and many of 119 00:06:00,920 --> 00:06:03,400 Speaker 5: the CFOs that are out there, how they operate every day. 120 00:06:04,080 --> 00:06:06,960 Speaker 2: So you mentioned that the CFO role is kind of 121 00:06:07,240 --> 00:06:10,240 Speaker 2: uniform across companies, but I have to imagine there are 122 00:06:10,320 --> 00:06:13,640 Speaker 2: some aspects of the pharma industry that make it a 123 00:06:13,640 --> 00:06:15,839 Speaker 2: little bit different, and one of them has to be 124 00:06:16,320 --> 00:06:20,040 Speaker 2: I guess the lead times in developing new treatments and 125 00:06:20,080 --> 00:06:23,919 Speaker 2: new medicines, and perhaps the risk as well. So you 126 00:06:24,000 --> 00:06:27,320 Speaker 2: might spend ten years developing this one thing and then 127 00:06:27,360 --> 00:06:29,400 Speaker 2: you find out at the very end that it has 128 00:06:29,440 --> 00:06:32,760 Speaker 2: an awful side effect or that the regulators aren't going 129 00:06:32,839 --> 00:06:36,280 Speaker 2: to approve it. How does that aspect of the business, 130 00:06:36,440 --> 00:06:39,400 Speaker 2: that uniqueness, feed into the CFO role. 131 00:06:39,720 --> 00:06:41,920 Speaker 5: Yeah, you're absolutely right, And maybe just to talk about 132 00:06:41,960 --> 00:06:44,520 Speaker 5: that process we call it, you know, we take a 133 00:06:44,560 --> 00:06:48,279 Speaker 5: drug from pure research to kind of pre clinical which 134 00:06:48,440 --> 00:06:50,440 Speaker 5: doesn't go into a human body, and you're kind of 135 00:06:50,480 --> 00:06:52,960 Speaker 5: testing how it works in the animals, and then it 136 00:06:53,080 --> 00:06:56,560 Speaker 5: gets into an IMD process or a new drug candidate, 137 00:06:56,839 --> 00:06:59,520 Speaker 5: and there are phase one, phase two, phase three, and 138 00:06:59,640 --> 00:07:02,520 Speaker 5: you're right, I mean, the probability is success from basic 139 00:07:02,600 --> 00:07:05,560 Speaker 5: research all the way through not only getting it launched 140 00:07:05,800 --> 00:07:08,120 Speaker 5: with the FDA in the United States as an example, 141 00:07:08,160 --> 00:07:11,560 Speaker 5: but there's healthcare regulators all across the globe, and. 142 00:07:11,480 --> 00:07:12,800 Speaker 4: Then commercial success as well. 143 00:07:12,880 --> 00:07:14,960 Speaker 5: So there's a ton of risk that goes into it, 144 00:07:15,200 --> 00:07:18,240 Speaker 5: and that's what we spend our time doing. And we 145 00:07:18,280 --> 00:07:21,000 Speaker 5: as a platform company believe that. You know, we've been 146 00:07:21,040 --> 00:07:24,840 Speaker 5: studying the science of mr anda in different verticals. A 147 00:07:24,960 --> 00:07:29,360 Speaker 5: vertical might be respiratory vaccines, as I mentioned, and if 148 00:07:29,400 --> 00:07:32,160 Speaker 5: we know that our mr and a platform can work 149 00:07:32,360 --> 00:07:35,080 Speaker 5: with COVID, then we have a high conviction that it 150 00:07:35,120 --> 00:07:37,200 Speaker 5: can work with RSP and a high conviction that it 151 00:07:37,240 --> 00:07:38,320 Speaker 5: can work with through another. 152 00:07:38,080 --> 00:07:40,680 Speaker 4: Respiratory and so we derisk that throughout the process. 153 00:07:41,120 --> 00:07:42,920 Speaker 5: We do it in basic research, we do it in 154 00:07:42,960 --> 00:07:45,360 Speaker 5: pre clinical, we do it in phase one trials, phase 155 00:07:45,360 --> 00:07:48,360 Speaker 5: two trials, and all those trials are just more patients. 156 00:07:48,360 --> 00:07:52,000 Speaker 5: So you might start with literally ten to fifteen patients 157 00:07:52,040 --> 00:07:53,680 Speaker 5: in phase one and then. 158 00:07:53,600 --> 00:07:54,720 Speaker 4: A respiratory trial. 159 00:07:54,920 --> 00:07:58,800 Speaker 5: Our RSP trial for phase three was thirty seven thousand patients. 160 00:07:59,160 --> 00:08:01,360 Speaker 5: And you just continue to assess what is the risk 161 00:08:01,400 --> 00:08:03,280 Speaker 5: and what is the capabilities, And so that's what we 162 00:08:03,320 --> 00:08:05,120 Speaker 5: spend a ton of time doing when we think about 163 00:08:05,160 --> 00:08:08,920 Speaker 5: allocating capital to our pipeline and our next drug candidates. 164 00:08:09,800 --> 00:08:12,880 Speaker 3: Talk to us a little bit more about that. I 165 00:08:12,880 --> 00:08:16,640 Speaker 3: think you said you had forty or forty something various 166 00:08:16,640 --> 00:08:20,840 Speaker 3: candidates in the pipeline. Obviously it'd be nice to have 167 00:08:21,200 --> 00:08:24,360 Speaker 3: unlimited money and work on all of them. You know, 168 00:08:24,400 --> 00:08:28,960 Speaker 3: when you are thinking about capital allocation, R and D allocation, 169 00:08:29,440 --> 00:08:33,640 Speaker 3: et cetera, Like, what are the factors that go into 170 00:08:33,679 --> 00:08:34,800 Speaker 3: making these decisions? 171 00:08:35,200 --> 00:08:39,239 Speaker 5: Sure, yeah, there's a lot, but I'll kind of summarize 172 00:08:39,240 --> 00:08:41,840 Speaker 5: it into a few, which is getting back to that 173 00:08:42,000 --> 00:08:46,400 Speaker 5: sense of risk and comparing it to our capabilities. So 174 00:08:46,960 --> 00:08:49,800 Speaker 5: I mentioned we have higher conviction and respiratory vaccines, so 175 00:08:49,840 --> 00:08:53,760 Speaker 5: therefore it's much easier to place bets and further dollars 176 00:08:53,800 --> 00:08:58,280 Speaker 5: behind respiratory vaccines. We are currently hoping to de risk 177 00:08:58,280 --> 00:09:03,360 Speaker 5: our latent vaccine therapeutic area. We've recently de risked our 178 00:09:04,040 --> 00:09:07,800 Speaker 5: oncology area, which we call individualized antigen therapy, which is 179 00:09:07,800 --> 00:09:11,520 Speaker 5: a mouthful, but in essence it helps stimulate key. 180 00:09:11,280 --> 00:09:12,480 Speaker 4: Sales to attack cancer. 181 00:09:13,320 --> 00:09:15,600 Speaker 5: And so when we look through it, we say, okay, 182 00:09:15,600 --> 00:09:19,760 Speaker 5: what is the mRNA capabilities? Have we derisked this area? 183 00:09:20,080 --> 00:09:22,840 Speaker 5: And therefore, you know, every step of the way, allocate 184 00:09:22,880 --> 00:09:23,280 Speaker 5: more dollars. 185 00:09:23,280 --> 00:09:25,360 Speaker 4: So that's number one. Number two is we look at 186 00:09:25,360 --> 00:09:26,280 Speaker 4: the size of the opportunity. 187 00:09:26,360 --> 00:09:28,280 Speaker 5: So this really isn't any different than any business case 188 00:09:28,320 --> 00:09:29,760 Speaker 5: for any company in any industry. 189 00:09:30,240 --> 00:09:32,559 Speaker 4: You know, respiratory vaccines is a very large market. 190 00:09:32,600 --> 00:09:36,000 Speaker 5: We think it's a thirty billion dollar market between flue, covid, 191 00:09:36,120 --> 00:09:38,760 Speaker 5: rsv SO, and there's only a few players, and there's 192 00:09:38,760 --> 00:09:41,320 Speaker 5: a very high barrier to entry because you have to 193 00:09:41,400 --> 00:09:44,160 Speaker 5: test so many patients and those trials are quite expensive. 194 00:09:44,960 --> 00:09:49,280 Speaker 5: Third is what's the competition and what's our commercial capabilities? 195 00:09:49,800 --> 00:09:52,520 Speaker 5: Will we be successful? Will we have something that differentiates 196 00:09:52,559 --> 00:09:55,560 Speaker 5: our product versus another product? And then the fourth is timing, 197 00:09:55,600 --> 00:09:59,600 Speaker 5: particularly when you're we're still a relatively young biotech company. 198 00:09:59,600 --> 00:10:02,480 Speaker 4: Thirteen years old is not that old in the grand 199 00:10:02,480 --> 00:10:02,920 Speaker 4: scheme of. 200 00:10:02,840 --> 00:10:06,800 Speaker 5: Things, and so therefore we have to understand Okay, what's 201 00:10:06,800 --> 00:10:09,160 Speaker 5: our cash balance? You know, how much revenue and profit 202 00:10:09,200 --> 00:10:11,240 Speaker 5: are we going to be generating in the next few years. 203 00:10:11,440 --> 00:10:13,800 Speaker 5: And therefore we want to turn over the portfolio to 204 00:10:13,840 --> 00:10:15,440 Speaker 5: not just be a COVID company, but to be a 205 00:10:15,520 --> 00:10:19,320 Speaker 5: multi drug company in various different areas. And so therefore 206 00:10:19,360 --> 00:10:21,079 Speaker 5: we look at, well, is this going to start generating 207 00:10:21,080 --> 00:10:23,600 Speaker 5: revenue in twenty twenty five, twenty twenty six, or some 208 00:10:23,679 --> 00:10:26,280 Speaker 5: of these won't be till twenty thirty five. So we 209 00:10:26,400 --> 00:10:28,319 Speaker 5: have to kind of balance all those things to make 210 00:10:28,320 --> 00:10:30,960 Speaker 5: sure that we have a sustainable company and bring the 211 00:10:31,000 --> 00:10:34,160 Speaker 5: most drugs to market with the highest probability of success. 212 00:10:34,600 --> 00:10:37,240 Speaker 2: So one thing that always interests me in these types 213 00:10:37,280 --> 00:10:41,680 Speaker 2: of conversations is the decision on allocating resources. And we're 214 00:10:41,679 --> 00:10:45,600 Speaker 2: talking about okay, thirteen years old, still relatively small in 215 00:10:45,880 --> 00:10:49,960 Speaker 2: the grand scheme of large pharma companies. But you have 216 00:10:50,000 --> 00:10:52,439 Speaker 2: a lot of people, you have a decent amount of money, 217 00:10:52,440 --> 00:10:55,679 Speaker 2: it seems, how do you decide where to put that 218 00:10:55,840 --> 00:10:59,240 Speaker 2: money to work? And I guess how granular do those 219 00:10:59,280 --> 00:11:02,520 Speaker 2: decisions actually get. Is there like a line item for 220 00:11:02,679 --> 00:11:05,800 Speaker 2: R and D expenses every year and it's just like 221 00:11:05,880 --> 00:11:08,800 Speaker 2: a big bundle and then there are people who are 222 00:11:08,840 --> 00:11:12,760 Speaker 2: specifically dedicated to dividing that up or would you, as CFO, 223 00:11:12,960 --> 00:11:16,160 Speaker 2: be like, I'm going to give X amount to this 224 00:11:16,280 --> 00:11:21,400 Speaker 2: project and why amount to this other developmental treatment. 225 00:11:22,080 --> 00:11:25,800 Speaker 5: Yeah, So at the high level, we work with the 226 00:11:25,840 --> 00:11:29,800 Speaker 5: executive team and the board to understand what is the 227 00:11:29,920 --> 00:11:32,640 Speaker 5: envelope of capital will give to R and D in 228 00:11:32,679 --> 00:11:36,600 Speaker 5: that example, because we also have to give capital to SGNA, 229 00:11:37,080 --> 00:11:40,559 Speaker 5: We have to give capital to capital expenditures, and historically 230 00:11:40,559 --> 00:11:42,160 Speaker 5: over the last couple of years, we had bought back shares, 231 00:11:42,200 --> 00:11:44,800 Speaker 5: although we've stopped buying backshares at this point because we 232 00:11:44,920 --> 00:11:45,800 Speaker 5: primarily want to. 233 00:11:45,760 --> 00:11:46,960 Speaker 4: Invest in this pipeline. 234 00:11:47,400 --> 00:11:49,599 Speaker 5: So after that, so once you size the envelope in 235 00:11:49,679 --> 00:11:51,520 Speaker 5: terms of, Okay, here's how much I'm willing to spend. 236 00:11:51,920 --> 00:11:53,800 Speaker 5: As an example, in twenty twenty four, we think we'll 237 00:11:53,840 --> 00:11:56,120 Speaker 5: spend approximately four and a half billion dollars. So then 238 00:11:56,160 --> 00:11:59,400 Speaker 5: the next step is, Okay, you have forty five drug candidates, 239 00:11:59,800 --> 00:12:02,000 Speaker 5: which ones why? Which is what I just kind of 240 00:12:02,000 --> 00:12:04,400 Speaker 5: talked through in terms of capabilities and the size of opportunities. 241 00:12:04,400 --> 00:12:06,120 Speaker 5: But just to maybe give a little bit more flavor, 242 00:12:07,040 --> 00:12:11,120 Speaker 5: a drug is not so simple, even COVID as an example, 243 00:12:11,520 --> 00:12:15,880 Speaker 5: you know, there's different patient populations. So there's the immunal compromised, 244 00:12:16,160 --> 00:12:20,440 Speaker 5: there's age sixty plus, there's age fifty to fifty nine, 245 00:12:21,040 --> 00:12:24,600 Speaker 5: there's age eighteen to forty nine, there's you know, I 246 00:12:24,640 --> 00:12:28,160 Speaker 5: think six to eighteen. And then there's pediatrics as well, 247 00:12:28,200 --> 00:12:31,880 Speaker 5: which all take a different level of testing and regulatory 248 00:12:32,000 --> 00:12:35,680 Speaker 5: oversight because there are different types of patients and the 249 00:12:35,720 --> 00:12:38,079 Speaker 5: bodies react in different ways, and the regulators want you 250 00:12:38,160 --> 00:12:41,640 Speaker 5: to study different things. So a lot of the actual 251 00:12:41,840 --> 00:12:44,839 Speaker 5: details is under Okay, yes, we've said we're going to 252 00:12:44,880 --> 00:12:47,640 Speaker 5: go with an RSV vaccine, where are we going to 253 00:12:47,720 --> 00:12:48,840 Speaker 5: start and how much will that cost? 254 00:12:48,960 --> 00:12:51,520 Speaker 4: And right now we've said age is sixty and over. 255 00:12:52,160 --> 00:12:54,599 Speaker 5: But then we might look at pediatrics because RSPA is 256 00:12:54,640 --> 00:13:00,600 Speaker 5: often hitting quite materially or significantly younger population. And so 257 00:13:00,679 --> 00:13:03,040 Speaker 5: that's kind of the next level of allocation, which is 258 00:13:03,080 --> 00:13:06,319 Speaker 5: you size the envelope, You then pick a program the 259 00:13:06,160 --> 00:13:09,000 Speaker 5: You then say which patient populations or indications are you 260 00:13:09,040 --> 00:13:11,840 Speaker 5: going to go after. Another example is oncology. So I 261 00:13:11,880 --> 00:13:13,920 Speaker 5: talked about this product that we have and we are 262 00:13:13,960 --> 00:13:18,360 Speaker 5: starting with adjuvant melanoma, and because adjuvant melanoma really in 263 00:13:18,400 --> 00:13:22,000 Speaker 5: immunooncology really seems to work quite well, and we are 264 00:13:22,040 --> 00:13:25,000 Speaker 5: kind of bundled with immunooncology and stimulating it even more. 265 00:13:25,440 --> 00:13:28,160 Speaker 4: And so we started there and it's you know, right now. 266 00:13:28,000 --> 00:13:31,760 Speaker 5: The data that we've released is quite positive over three 267 00:13:31,840 --> 00:13:34,640 Speaker 5: years and improves the life of a patient's success in 268 00:13:34,720 --> 00:13:37,680 Speaker 5: terms of recurrence or death by fifty percent, which is 269 00:13:37,760 --> 00:13:40,800 Speaker 5: outstanding in terms of cancer. And then you've got to 270 00:13:40,800 --> 00:13:43,800 Speaker 5: figure out, well, there's you know, loads of different cancer types, 271 00:13:43,960 --> 00:13:46,600 Speaker 5: where will this product work best? And that's what we 272 00:13:47,080 --> 00:13:49,160 Speaker 5: try to determine every single day as we get more 273 00:13:49,160 --> 00:13:51,680 Speaker 5: and more specific underneath that envelope the capital. 274 00:14:07,360 --> 00:14:09,880 Speaker 3: What is the process by which I mean I have 275 00:14:09,920 --> 00:14:15,080 Speaker 3: to imagine that with e within each internal candidate, the 276 00:14:15,160 --> 00:14:18,520 Speaker 3: various scientists, the various teams, like they probably want more 277 00:14:18,960 --> 00:14:22,440 Speaker 3: for their the specific thing that they're working on. What 278 00:14:22,720 --> 00:14:26,480 Speaker 3: is this sort of internal process? Is it a sort 279 00:14:26,520 --> 00:14:30,960 Speaker 3: of is it an internal lobbying process? That's sort of 280 00:14:31,000 --> 00:14:32,480 Speaker 3: what I imagine my head where they come to you 281 00:14:32,520 --> 00:14:34,440 Speaker 3: and they're like, look, we believe that we can do this, 282 00:14:34,960 --> 00:14:37,560 Speaker 3: and if we could increase the R and D on 283 00:14:37,680 --> 00:14:40,040 Speaker 3: this thing, then we believe that we can maybe get 284 00:14:40,080 --> 00:14:42,200 Speaker 3: it to market or get to the next stage of 285 00:14:42,200 --> 00:14:44,720 Speaker 3: trials faster than X. Like, what is sort of your 286 00:14:44,880 --> 00:14:49,000 Speaker 3: internal process for working with the various champions of different 287 00:14:49,120 --> 00:14:52,600 Speaker 3: potential products where they make the case that they could 288 00:14:52,720 --> 00:14:54,280 Speaker 3: use money in a productive way. 289 00:14:54,680 --> 00:14:54,960 Speaker 4: Yeah. 290 00:14:55,000 --> 00:14:59,200 Speaker 5: So, first and I tell every industry, we could certainly 291 00:14:59,200 --> 00:15:01,080 Speaker 5: spend a lot more than four and a half billion dollars, 292 00:15:01,160 --> 00:15:03,320 Speaker 5: and that is a wonderful thing, because the minute we 293 00:15:03,400 --> 00:15:06,760 Speaker 5: run out of ideas and pipelines, we're in trouble and 294 00:15:06,800 --> 00:15:07,600 Speaker 5: we'll stop growing. 295 00:15:07,640 --> 00:15:12,560 Speaker 4: So it is definitely a hot debate, I would say, 296 00:15:12,600 --> 00:15:14,400 Speaker 4: in terms of where we're going to allocate our capital. 297 00:15:14,400 --> 00:15:17,520 Speaker 4: But let me just give you maybe I'd say three 298 00:15:17,920 --> 00:15:19,720 Speaker 4: processes that we run. Great. 299 00:15:20,000 --> 00:15:23,200 Speaker 5: So, first off, we have twice a year a look 300 00:15:23,240 --> 00:15:27,280 Speaker 5: at our entire portfolio and we call it a strategy 301 00:15:27,280 --> 00:15:31,520 Speaker 5: review to understand, Okay, let's make these decisions, given the envelope, 302 00:15:31,560 --> 00:15:34,120 Speaker 5: the capital we have, let's prioritize these things and we 303 00:15:34,200 --> 00:15:34,760 Speaker 5: pull together. 304 00:15:34,920 --> 00:15:39,600 Speaker 4: It's extremely cross functional. It is even within R and D. 305 00:15:39,680 --> 00:15:41,720 Speaker 5: There are many different functions within R and D, and 306 00:15:41,760 --> 00:15:43,920 Speaker 5: we bring in all of those people that are product 307 00:15:44,000 --> 00:15:49,800 Speaker 5: specialists or epidemiologists or development specialists, et cetera. We bring 308 00:15:49,840 --> 00:15:52,280 Speaker 5: in the finance team to obviously run the financials and 309 00:15:52,360 --> 00:15:55,040 Speaker 5: understand the reward, the commercial team to understand the size 310 00:15:55,080 --> 00:15:58,840 Speaker 5: of the opportunity, and we debate and say, okay, strategically, 311 00:15:58,840 --> 00:16:01,440 Speaker 5: as a company, if we want to be this year, 312 00:16:01,480 --> 00:16:04,040 Speaker 5: we think we'll be four billion in sales. If we 313 00:16:04,080 --> 00:16:06,720 Speaker 5: want to get to I'll just make it up a number, 314 00:16:06,840 --> 00:16:10,000 Speaker 5: say ten billion dollars in sales by twenty twenty seven. 315 00:16:10,440 --> 00:16:13,040 Speaker 5: And if that's a priority, that's not the only priority, 316 00:16:13,040 --> 00:16:15,200 Speaker 5: but that is a priority to say, okay, let's have 317 00:16:15,240 --> 00:16:16,040 Speaker 5: that lens on it. 318 00:16:16,360 --> 00:16:18,360 Speaker 4: Number one. Number two, here's another lens. 319 00:16:18,440 --> 00:16:20,480 Speaker 5: We want to diversify our revenue streams, so we don't 320 00:16:20,480 --> 00:16:22,680 Speaker 5: want to be solely a respiratory business. So we've got 321 00:16:22,720 --> 00:16:26,080 Speaker 5: to make sure we are investing in other latent areas, 322 00:16:26,160 --> 00:16:29,160 Speaker 5: latent disease areas or oncology that we also want to 323 00:16:29,160 --> 00:16:31,880 Speaker 5: bring to market, and we have those strategic and that 324 00:16:31,960 --> 00:16:33,240 Speaker 5: kind of sets the foundation. 325 00:16:33,800 --> 00:16:35,840 Speaker 4: Then. So that's process one that happens twice. 326 00:16:35,640 --> 00:16:37,320 Speaker 5: A year, and we figure out which products we want 327 00:16:37,360 --> 00:16:39,760 Speaker 5: to fund in theory, and that's what we start co 328 00:16:39,760 --> 00:16:43,560 Speaker 5: operating too. But then there's underlying research and clinical trials 329 00:16:43,560 --> 00:16:46,240 Speaker 5: that are going on every single day, and there's report 330 00:16:46,280 --> 00:16:48,960 Speaker 5: outs and you might get different data, different answers that 331 00:16:49,040 --> 00:16:53,160 Speaker 5: actually changes that and that is a very well governed 332 00:16:53,200 --> 00:16:57,080 Speaker 5: process that we call a stage gay process. And as 333 00:16:57,120 --> 00:17:00,240 Speaker 5: an example, you know, I myself have to approve whether 334 00:17:00,240 --> 00:17:02,240 Speaker 5: we go to a phase three trial because those are 335 00:17:02,360 --> 00:17:05,439 Speaker 5: very expensive, as I mentioned earlier, so you know, but 336 00:17:05,480 --> 00:17:08,520 Speaker 5: there are gates into even before it gets into the 337 00:17:08,560 --> 00:17:11,760 Speaker 5: clinical there's gates in the research area, in pre clinical area, 338 00:17:12,080 --> 00:17:13,920 Speaker 5: and then there's gates before you go to phase one, 339 00:17:13,960 --> 00:17:16,879 Speaker 5: phase two, phase three, and those you know, we have 340 00:17:16,960 --> 00:17:19,600 Speaker 5: a theory based on the strategy of what we wanted 341 00:17:19,600 --> 00:17:21,639 Speaker 5: to invest in, but new data. 342 00:17:21,359 --> 00:17:22,800 Speaker 4: Comes out and you have to adjust to it. 343 00:17:23,080 --> 00:17:25,000 Speaker 5: So I'd say that's kind of the second process that 344 00:17:25,119 --> 00:17:28,199 Speaker 5: is highly governed. So you have this top level strategy, 345 00:17:28,359 --> 00:17:30,720 Speaker 5: then you have actual data that's coming through that is 346 00:17:30,720 --> 00:17:33,280 Speaker 5: well governed. And then the last thing is particularly on 347 00:17:33,640 --> 00:17:35,240 Speaker 5: how much we're going to spend and whether we go 348 00:17:35,480 --> 00:17:37,480 Speaker 5: and spend more on these phase three trials. We actually 349 00:17:37,480 --> 00:17:39,879 Speaker 5: take it to a subcommittee of the board, so the 350 00:17:39,880 --> 00:17:42,720 Speaker 5: Board of Directors, which we have some scientists and doctors 351 00:17:42,720 --> 00:17:44,679 Speaker 5: that are on our board and oversee it and have 352 00:17:44,680 --> 00:17:48,240 Speaker 5: a lot of experience also govern Yeah, we think it's worse. 353 00:17:48,320 --> 00:17:49,880 Speaker 5: We get it, we get the strategy. If it's into 354 00:17:49,920 --> 00:17:51,760 Speaker 5: our strategy, we understand the risks, and we think you 355 00:17:51,800 --> 00:17:54,959 Speaker 5: should move forward. So those are kind of three different 356 00:17:55,000 --> 00:17:57,960 Speaker 5: processes in terms of how we govern our product strategies. 357 00:17:58,240 --> 00:18:01,280 Speaker 2: Where does the money actually come from? And I realized 358 00:18:01,280 --> 00:18:05,239 Speaker 2: like maybe maybe there's some obvious answers here. You are 359 00:18:05,400 --> 00:18:08,160 Speaker 2: a publicly traded company, but this is a really capital 360 00:18:08,359 --> 00:18:12,840 Speaker 2: intensive business. And I was looking on the Bloomberg terminal earlier. 361 00:18:13,200 --> 00:18:16,560 Speaker 2: It doesn't seem like you have any bonds, which is 362 00:18:16,960 --> 00:18:21,919 Speaker 2: kind of unusual nowadays. Where does that like funding mix 363 00:18:22,119 --> 00:18:23,200 Speaker 2: actually come from. 364 00:18:23,480 --> 00:18:26,760 Speaker 5: Yeah, so I'll chase the answer that question in the industry, 365 00:18:26,760 --> 00:18:28,480 Speaker 5: but also the specific to us because we're a little 366 00:18:28,480 --> 00:18:32,359 Speaker 5: bit different. Sure, so specific to us, we actually, because 367 00:18:32,440 --> 00:18:35,960 Speaker 5: of COVID and how successful our vaccine was to help 368 00:18:36,000 --> 00:18:39,480 Speaker 5: support the global population, we're actually sitting on thirteen billion 369 00:18:39,560 --> 00:18:43,240 Speaker 5: dollars in cash. That is very unique to a biotech company. 370 00:18:43,400 --> 00:18:46,440 Speaker 5: So we are quite fortunate. And as an example, we 371 00:18:46,480 --> 00:18:48,480 Speaker 5: said this year we're going to actually burn through four 372 00:18:48,520 --> 00:18:50,600 Speaker 5: billion dollars in cash. So we believe in this platform 373 00:18:50,680 --> 00:18:52,320 Speaker 5: so much that we need to advance the next set 374 00:18:52,320 --> 00:18:53,960 Speaker 5: of pipeline of drug candidates. 375 00:18:54,600 --> 00:18:56,720 Speaker 4: And we have a plan all the way for the 376 00:18:56,720 --> 00:18:57,320 Speaker 4: next three. 377 00:18:57,119 --> 00:18:59,320 Speaker 5: To five years that we're actually going to go from 378 00:18:59,400 --> 00:19:01,840 Speaker 5: thirteen billion to nine billion in the year twenty twenty 379 00:19:01,840 --> 00:19:03,520 Speaker 5: four because we think it's the right thing to do. 380 00:19:03,680 --> 00:19:04,840 Speaker 5: And then we said we're going to do it a 381 00:19:04,840 --> 00:19:06,439 Speaker 5: little bit again, that we're going to burn another two 382 00:19:06,480 --> 00:19:08,800 Speaker 5: to three billion in twenty twenty five before breaking even 383 00:19:08,840 --> 00:19:11,800 Speaker 5: in twenty twenty six as we'd launch new drugs. So 384 00:19:11,920 --> 00:19:14,720 Speaker 5: that's a bit unique in the biotech world, I would 385 00:19:14,720 --> 00:19:18,560 Speaker 5: say broadly though for the sector, there are various avenues 386 00:19:18,560 --> 00:19:22,000 Speaker 5: that obviously public investors, capital markets, like you said, there 387 00:19:22,040 --> 00:19:25,560 Speaker 5: are some government projects with Barta Covid as an example, 388 00:19:25,800 --> 00:19:28,440 Speaker 5: the US government helped fund some of the COVID research 389 00:19:28,480 --> 00:19:31,399 Speaker 5: and development of our product, and so there are different 390 00:19:31,440 --> 00:19:33,760 Speaker 5: government agencies across the globe that you can tap into. 391 00:19:34,359 --> 00:19:35,280 Speaker 4: There are other companies. 392 00:19:35,320 --> 00:19:38,120 Speaker 5: So before we were you know, before Covid, we had 393 00:19:38,160 --> 00:19:40,520 Speaker 5: no we had no products that had ever been approved, 394 00:19:41,240 --> 00:19:44,840 Speaker 5: and so we started in twenty eleven and in twenty 395 00:19:44,960 --> 00:19:47,880 Speaker 5: sixteen we actually went to a different company, company called Merk. 396 00:19:48,280 --> 00:19:51,480 Speaker 5: I'm sure you've heard of them, and they actually helped 397 00:19:51,520 --> 00:19:55,520 Speaker 5: fund our oncology product because it is in conjunction with 398 00:19:55,560 --> 00:19:59,320 Speaker 5: their product k Trudea. So that's another outlet for capital 399 00:19:59,320 --> 00:20:02,320 Speaker 5: that you can part with a collaboration where you know, 400 00:20:02,760 --> 00:20:05,080 Speaker 5: a company like Mark gave us I think two hundred 401 00:20:05,080 --> 00:20:07,760 Speaker 5: and fifty million dollars back in twenty sixteen to launch 402 00:20:07,840 --> 00:20:10,480 Speaker 5: this product and advance the science that is now so 403 00:20:10,640 --> 00:20:14,439 Speaker 5: fruitful come twenty twenty four. And then the last one 404 00:20:14,520 --> 00:20:17,160 Speaker 5: is just foundations, and we tap into foundations as well, 405 00:20:17,560 --> 00:20:20,200 Speaker 5: not as much now that we have a fair amount 406 00:20:20,200 --> 00:20:23,560 Speaker 5: of funding ourselves, but Bell and Melinda Gates as an example, 407 00:20:23,600 --> 00:20:26,680 Speaker 5: we were working with them on certain infectious disease vaccines. 408 00:20:26,800 --> 00:20:29,640 Speaker 5: So those are kind of the areas. So it's capital markets, 409 00:20:29,680 --> 00:20:33,160 Speaker 5: it's the government, it's other companies and collaborations that might 410 00:20:33,240 --> 00:20:36,440 Speaker 5: fund it, and then there's foundations as well. 411 00:20:36,560 --> 00:20:38,879 Speaker 3: Let's talk about the role of the government. One of 412 00:20:38,920 --> 00:20:42,919 Speaker 3: the extraordinary things, and you know, Operation Warp Speed was 413 00:20:42,960 --> 00:20:47,520 Speaker 3: sort of this incredible endeavor that involved upfront money and 414 00:20:47,680 --> 00:20:52,280 Speaker 3: also advanced purchasing agreement so that once you got the 415 00:20:52,359 --> 00:20:55,879 Speaker 3: vaccine to market that you had guaranteed sales talk to 416 00:20:55,960 --> 00:21:00,119 Speaker 3: us just about the math of Operation Warp Speed, what 417 00:21:00,200 --> 00:21:03,920 Speaker 3: it meant for Maderi NA, and then specifically the power 418 00:21:04,240 --> 00:21:07,199 Speaker 3: of the advanced purchase agreements and whether that is a 419 00:21:07,280 --> 00:21:11,560 Speaker 3: model that you see being replicated going forwards, like a 420 00:21:11,680 --> 00:21:14,240 Speaker 3: sort of a way of de risking the entire process. 421 00:21:14,480 --> 00:21:14,720 Speaker 4: Sure. 422 00:21:14,800 --> 00:21:17,920 Speaker 5: Yeah, as you and I spoke beforehand, Joe, I wasn't 423 00:21:17,960 --> 00:21:20,399 Speaker 5: here during COVID. I joined the company at the end 424 00:21:20,400 --> 00:21:22,240 Speaker 5: of twenty twenty two, in September of twenty two, so 425 00:21:22,240 --> 00:21:24,639 Speaker 5: I've been here for eighteen months, so I obviously am 426 00:21:24,680 --> 00:21:26,400 Speaker 5: aware of what went on, but I don't know all 427 00:21:26,480 --> 00:21:28,879 Speaker 5: the intimate details. So I'll give you my general opinion 428 00:21:28,920 --> 00:21:31,720 Speaker 5: and impression, and you know it works. Me. I forget 429 00:21:31,720 --> 00:21:34,119 Speaker 5: the exact money, but I think it might be in 430 00:21:34,160 --> 00:21:36,040 Speaker 5: the range of a billion dollars. Don't quote me on that. 431 00:21:36,119 --> 00:21:38,480 Speaker 5: It's in our disclosures. You can actually pull it up 432 00:21:38,520 --> 00:21:41,119 Speaker 5: and get the exact numbers. But it was not insignificant. 433 00:21:41,600 --> 00:21:44,440 Speaker 5: And I think this is an example of a terrific 434 00:21:45,080 --> 00:21:48,320 Speaker 5: public private partnership that actually did great for the world. 435 00:21:49,119 --> 00:21:52,359 Speaker 5: And to put that into perspective, and it wasn't just 436 00:21:52,359 --> 00:21:54,080 Speaker 5: the funding. By the way, we can get into it. 437 00:21:54,200 --> 00:21:56,919 Speaker 5: There was so much help throughout the entire process in 438 00:21:57,000 --> 00:22:01,479 Speaker 5: twenty twenty in many different areas, shippings, et cetera. A 439 00:22:01,480 --> 00:22:04,080 Speaker 5: lot of red tape to cut through, but it actually 440 00:22:04,240 --> 00:22:07,720 Speaker 5: proves that in one year we went from COVID that 441 00:22:07,840 --> 00:22:12,440 Speaker 5: came out, we identified the vaccine in two days, and. 442 00:22:12,359 --> 00:22:15,400 Speaker 4: We got it approved from market in eleven months. 443 00:22:15,920 --> 00:22:20,919 Speaker 5: That is unparalleled in the pharmaceutical biotech industry. And so 444 00:22:21,440 --> 00:22:23,199 Speaker 5: it shows you the art of the possible. There is 445 00:22:23,480 --> 00:22:27,160 Speaker 5: good reason why things are regulated because there's safety concerns 446 00:22:27,200 --> 00:22:29,560 Speaker 5: and we have to do that, but it also shows 447 00:22:29,600 --> 00:22:32,040 Speaker 5: you that you can accelerate this timeline if you cut 448 00:22:32,040 --> 00:22:35,040 Speaker 5: through some red tape for something that has been very powerful, 449 00:22:35,480 --> 00:22:37,880 Speaker 5: very safe and effective and really has changed the world 450 00:22:37,920 --> 00:22:40,439 Speaker 5: in a very rapid way. So I'm a huge believer 451 00:22:40,520 --> 00:22:43,480 Speaker 5: in the success of that. In terms of the APA SEAH, 452 00:22:43,480 --> 00:22:46,960 Speaker 5: I mean to think about our situation. We had zero 453 00:22:47,119 --> 00:22:51,560 Speaker 5: revenue and we were asked to go invest literally hundreds 454 00:22:51,560 --> 00:22:53,840 Speaker 5: and billions of dollars to get this over the hump. 455 00:22:54,160 --> 00:22:57,120 Speaker 5: It was a make or break decision for us. I mean, 456 00:22:57,160 --> 00:23:00,600 Speaker 5: we were sitting there going we were public company. You 457 00:23:00,600 --> 00:23:03,280 Speaker 5: could run out of cash and a heartbeat, and so 458 00:23:03,640 --> 00:23:05,600 Speaker 5: we you know, we needed a partner to help take 459 00:23:05,640 --> 00:23:09,000 Speaker 5: that risk, and ultimately it worked out and worked very well. 460 00:23:09,080 --> 00:23:11,560 Speaker 4: So the APAs to your second part of your question 461 00:23:11,600 --> 00:23:12,480 Speaker 4: there were. 462 00:23:12,400 --> 00:23:14,159 Speaker 5: Very important because we had to know that if we're 463 00:23:14,160 --> 00:23:16,440 Speaker 5: going to go invest all this money and in our infrastructure, 464 00:23:16,480 --> 00:23:19,280 Speaker 5: forget about the research and development, we have to bring 465 00:23:19,359 --> 00:23:23,360 Speaker 5: on six different manufacturing partners across the globe. We had 466 00:23:23,359 --> 00:23:26,800 Speaker 5: to go make purchase commitments for inventory in the billions 467 00:23:26,840 --> 00:23:29,400 Speaker 5: of dollars with part you know, to say, hey, we 468 00:23:29,520 --> 00:23:31,440 Speaker 5: need we need to make a lot of COVID doses 469 00:23:31,480 --> 00:23:33,880 Speaker 5: over a billion on that time period that we made 470 00:23:34,119 --> 00:23:36,520 Speaker 5: a billion doses as this and we had that was a. 471 00:23:36,440 --> 00:23:36,920 Speaker 4: Lot of risk. 472 00:23:37,040 --> 00:23:38,560 Speaker 5: We needed to know that we were going to get 473 00:23:38,600 --> 00:23:40,800 Speaker 5: some return otherwise, you know, we were going to turn 474 00:23:40,880 --> 00:23:41,360 Speaker 5: upside down. 475 00:23:41,960 --> 00:23:43,760 Speaker 4: So APAs were important. 476 00:23:44,000 --> 00:23:46,600 Speaker 5: I believe that a partnership can work quite well, and 477 00:23:46,640 --> 00:23:49,320 Speaker 5: in this example, I think it works extremely well. I 478 00:23:49,440 --> 00:23:53,280 Speaker 5: get that there needs to be regulation for many different reasons, 479 00:23:53,320 --> 00:23:55,160 Speaker 5: but I think that shows you the art of the possible, 480 00:23:55,200 --> 00:23:58,160 Speaker 5: both in public private partnerships as well as what can 481 00:23:58,200 --> 00:24:01,920 Speaker 5: happen when you really try to expectegulatory process here's. 482 00:24:01,720 --> 00:24:04,600 Speaker 2: One thing I always wonder when it comes to CFOs 483 00:24:04,640 --> 00:24:07,399 Speaker 2: and their sort of daily life. But Joe has a 484 00:24:07,440 --> 00:24:10,480 Speaker 2: line that I think it actually came from Neil Data 485 00:24:10,600 --> 00:24:13,399 Speaker 2: and you co opted it. But the stock market is 486 00:24:13,440 --> 00:24:16,879 Speaker 2: not the economy. But it's not not the economy. And 487 00:24:16,920 --> 00:24:20,960 Speaker 2: when share prices go up, that means there's more availability 488 00:24:21,000 --> 00:24:24,280 Speaker 2: of funding for companies in general. So first of all, 489 00:24:24,560 --> 00:24:27,359 Speaker 2: how closely do you watch the moderna stock price? Is 490 00:24:27,359 --> 00:24:29,320 Speaker 2: that like the first thing you look at when you 491 00:24:29,359 --> 00:24:30,679 Speaker 2: come into the office every morning. 492 00:24:34,200 --> 00:24:36,640 Speaker 4: I mean I certainly monitor it quite a bit. Yes, 493 00:24:36,680 --> 00:24:39,200 Speaker 4: I do. It's important. I mean it's one of the 494 00:24:39,240 --> 00:24:40,600 Speaker 4: key stakeholders. 495 00:24:40,000 --> 00:24:43,200 Speaker 5: And one that I know most importantly own, which is 496 00:24:43,240 --> 00:24:43,960 Speaker 5: our investors. 497 00:24:44,000 --> 00:24:46,520 Speaker 4: So I have to make sure I'm watching that. And 498 00:24:46,560 --> 00:24:48,520 Speaker 4: so yes, I actually watch it in a fair amount. 499 00:24:49,119 --> 00:24:51,960 Speaker 2: And then okay, what do you think when it starts 500 00:24:52,119 --> 00:24:54,800 Speaker 2: going down? Is there like a thought process in your 501 00:24:54,840 --> 00:24:58,200 Speaker 2: head that says, oh, we need to think about specific 502 00:24:58,280 --> 00:25:01,840 Speaker 2: things that we could be doing to boost shares or 503 00:25:02,080 --> 00:25:04,320 Speaker 2: do you start thinking, well, you know, there are other 504 00:25:04,359 --> 00:25:07,840 Speaker 2: things going on in the economy, interest rates are going up. 505 00:25:07,920 --> 00:25:11,080 Speaker 2: That sort of thing. I just wonder, you know, put 506 00:25:11,119 --> 00:25:14,200 Speaker 2: us inside your mind for a second. As a CFO, 507 00:25:14,359 --> 00:25:16,879 Speaker 2: when you look at a share price, what is happening 508 00:25:16,920 --> 00:25:17,400 Speaker 2: in your head? 509 00:25:17,800 --> 00:25:18,600 Speaker 4: Yeah? I try. 510 00:25:18,680 --> 00:25:22,479 Speaker 5: I try to assess for really rapid movement, what is 511 00:25:22,520 --> 00:25:25,240 Speaker 5: going on? You know, day to day, stock's going to 512 00:25:25,320 --> 00:25:26,600 Speaker 5: jump all that, you know, a little bit up, a 513 00:25:26,600 --> 00:25:27,399 Speaker 5: little bit down, a little bit. 514 00:25:27,600 --> 00:25:28,480 Speaker 4: That happens all the time. 515 00:25:29,160 --> 00:25:32,040 Speaker 5: So I try to assess, Okay, Number one, is it 516 00:25:32,080 --> 00:25:36,320 Speaker 5: a specific event for us? A news item, whether it's 517 00:25:36,320 --> 00:25:40,280 Speaker 5: a regulatory update on a clinical trial, or whether we 518 00:25:40,440 --> 00:25:43,600 Speaker 5: give you know, guidance on financials or whatever it might be. 519 00:25:43,680 --> 00:25:46,040 Speaker 4: Is it a specific event? Did we do it well? 520 00:25:46,119 --> 00:25:47,360 Speaker 4: You know, we take that quite. 521 00:25:47,240 --> 00:25:49,399 Speaker 5: Seriously, and did we communicate it well where we clear 522 00:25:49,440 --> 00:25:51,760 Speaker 5: do people get it to investors get it? And even 523 00:25:51,760 --> 00:25:53,639 Speaker 5: if they get it, you know, if it's bad news, 524 00:25:53,760 --> 00:25:57,119 Speaker 5: the stock may go down, but they understand it and 525 00:25:57,359 --> 00:26:00,359 Speaker 5: there's a natural you know, implication to that. Or if 526 00:26:00,359 --> 00:26:02,520 Speaker 5: the stock goes up, they are clearly understanding the message 527 00:26:02,560 --> 00:26:03,199 Speaker 5: of what we're trying to say. 528 00:26:03,240 --> 00:26:04,560 Speaker 4: So I try to understand Number one, is there a 529 00:26:04,560 --> 00:26:05,680 Speaker 4: specific event for us? 530 00:26:06,560 --> 00:26:09,840 Speaker 5: The everyday events in terms of just the global economy 531 00:26:09,840 --> 00:26:13,879 Speaker 5: and interest rates worry me less. We're fortunate as I 532 00:26:13,920 --> 00:26:15,720 Speaker 5: mentioned to have thirteen billion dollars in cash. 533 00:26:15,720 --> 00:26:18,200 Speaker 4: We don't take it lightly. We try to understand what that. 534 00:26:18,119 --> 00:26:20,520 Speaker 5: Means for us over the coming years in terms of, Okay, 535 00:26:20,520 --> 00:26:23,399 Speaker 5: what's going to happen from a demand perspective, or you know, 536 00:26:23,440 --> 00:26:25,399 Speaker 5: the cash in the bank will return interest, And so 537 00:26:25,440 --> 00:26:28,399 Speaker 5: we obviously are cognizant on the of the implications on 538 00:26:28,440 --> 00:26:32,320 Speaker 5: our company, but overall, we're I think we spend the 539 00:26:32,359 --> 00:26:36,840 Speaker 5: most time focusing on our investors understanding the long term 540 00:26:36,880 --> 00:26:38,360 Speaker 5: opportunity for our company. 541 00:26:38,920 --> 00:26:41,800 Speaker 4: And I think that's what's critical for many companies. And 542 00:26:41,840 --> 00:26:42,960 Speaker 4: it is hard to. 543 00:26:42,920 --> 00:26:46,600 Speaker 5: Have investors really look at the long term, and you know, 544 00:26:46,880 --> 00:26:50,240 Speaker 5: different portfolio managers, investors have a different view on what 545 00:26:50,320 --> 00:26:53,480 Speaker 5: is long term, whether that's twenty four months, five years, 546 00:26:53,480 --> 00:26:55,919 Speaker 5: ten years, And we try to make sure that people. 547 00:26:55,680 --> 00:26:58,199 Speaker 4: Understand what is the opportunity ahead and. 548 00:26:58,720 --> 00:27:01,359 Speaker 5: Actually if they are saying it back to us, then 549 00:27:01,680 --> 00:27:04,280 Speaker 5: at least they understand it and they might make a 550 00:27:04,280 --> 00:27:07,199 Speaker 5: different decision, might wait for it, you know, and we 551 00:27:07,240 --> 00:27:08,840 Speaker 5: try to understand what does that mean in terms of 552 00:27:08,840 --> 00:27:09,720 Speaker 5: their buying behavior. 553 00:27:09,760 --> 00:27:10,800 Speaker 4: But that's what we. 554 00:27:10,720 --> 00:27:13,040 Speaker 5: Spend the most time doing, is to under just make 555 00:27:13,080 --> 00:27:16,439 Speaker 5: sure our investors understand our long term strategy and do 556 00:27:16,480 --> 00:27:30,639 Speaker 5: they believe in where we're going. 557 00:27:33,280 --> 00:27:37,439 Speaker 3: It does seem like for companies in some areas that 558 00:27:37,520 --> 00:27:41,119 Speaker 3: when a stock is moving lower or maybe higher, but 559 00:27:41,119 --> 00:27:43,480 Speaker 3: when this dog is moving lower, that there is an 560 00:27:43,520 --> 00:27:46,000 Speaker 3: impulse to course correct in some way. And so you 561 00:27:46,040 --> 00:27:49,280 Speaker 3: saw this, for example, I think within big tech, where 562 00:27:49,320 --> 00:27:51,560 Speaker 3: we saw this pretty big sell off in twenty twenty 563 00:27:51,600 --> 00:27:54,399 Speaker 3: two and a bunch of companies seem to get the 564 00:27:54,440 --> 00:27:56,760 Speaker 3: message like, oh, you know what, we really need to 565 00:27:56,800 --> 00:28:00,399 Speaker 3: slow our hiring, or maybe we shouldn't bet the entire 566 00:28:00,520 --> 00:28:03,440 Speaker 3: company on virtual reality goggles, and we need to cut 567 00:28:03,480 --> 00:28:06,000 Speaker 3: our research in this area. That there is this message 568 00:28:06,000 --> 00:28:08,680 Speaker 3: about something, and then you see the layoffs and they're like, look, 569 00:28:08,680 --> 00:28:11,840 Speaker 3: we've done much better about reducing our cash burned, et cetera. 570 00:28:12,520 --> 00:28:14,520 Speaker 3: Do you take a signal I mean, I get there 571 00:28:14,560 --> 00:28:16,959 Speaker 3: are certain things that are out of your control that 572 00:28:17,000 --> 00:28:18,840 Speaker 3: you have a long term message that you want to 573 00:28:18,840 --> 00:28:21,640 Speaker 3: tell the shareholders. But do you take a signal from 574 00:28:21,920 --> 00:28:25,639 Speaker 3: larger moves in the market that say, look, the investors 575 00:28:25,720 --> 00:28:28,520 Speaker 3: want to see X, and we need to course correct 576 00:28:28,560 --> 00:28:32,440 Speaker 3: in some way or another in order to align our goals. 577 00:28:32,840 --> 00:28:33,719 Speaker 4: That's a great question. 578 00:28:33,920 --> 00:28:37,600 Speaker 5: So I think, if there's a big move, and we 579 00:28:37,600 --> 00:28:39,920 Speaker 5: should be doing this all the time, but there's something 580 00:28:39,960 --> 00:28:43,120 Speaker 5: to listen to, and so I'll just take myself out 581 00:28:43,120 --> 00:28:45,959 Speaker 5: of Maderna. I mean, if you're a CFO and your 582 00:28:46,000 --> 00:28:49,120 Speaker 5: stock goes down twenty percent, that is a substantial amount 583 00:28:49,160 --> 00:28:52,240 Speaker 5: of investors saying it is less valuable. Something's going on, 584 00:28:52,880 --> 00:28:54,800 Speaker 5: And I think what you have to listen for is 585 00:28:55,240 --> 00:28:57,400 Speaker 5: do we already know that or is it something that 586 00:28:57,440 --> 00:29:00,280 Speaker 5: we really have We got to think differently about. So 587 00:29:00,520 --> 00:29:02,200 Speaker 5: is our revenue line not going to be what we 588 00:29:02,200 --> 00:29:03,880 Speaker 5: think it's going to be? And the investors are ahead 589 00:29:03,880 --> 00:29:05,720 Speaker 5: of us because they see something in the marketplace that 590 00:29:05,800 --> 00:29:09,000 Speaker 5: is changing. And if that's the case, then sometimes I 591 00:29:09,040 --> 00:29:12,200 Speaker 5: mean I take our conversations with investors as a two 592 00:29:12,240 --> 00:29:12,800 Speaker 5: way learning. 593 00:29:13,320 --> 00:29:14,120 Speaker 4: I learned from them. 594 00:29:14,200 --> 00:29:16,080 Speaker 5: They give me their thoughts on what they think that 595 00:29:16,160 --> 00:29:18,760 Speaker 5: where the market's going, where we're positioned, how we're positioned, 596 00:29:19,360 --> 00:29:21,280 Speaker 5: how successful they think we're going to be, just as 597 00:29:21,360 --> 00:29:23,320 Speaker 5: much as I try to tell them our view. And 598 00:29:23,360 --> 00:29:25,440 Speaker 5: so it is a two way learning. And especially when 599 00:29:25,520 --> 00:29:29,160 Speaker 5: there's a huge market move or significant market move, they're. 600 00:29:29,000 --> 00:29:29,800 Speaker 4: Telling you something. 601 00:29:31,400 --> 00:29:33,200 Speaker 5: The question of what you have to sift through is 602 00:29:33,320 --> 00:29:35,720 Speaker 5: did we already know that and therefore just stay the 603 00:29:35,760 --> 00:29:38,760 Speaker 5: course on strategy, or is it something that, hey, we 604 00:29:38,840 --> 00:29:41,200 Speaker 5: might need to think differently about and perhaps we're wrong 605 00:29:41,240 --> 00:29:44,040 Speaker 5: on one of our assumptions. So that's how I deal with, 606 00:29:44,080 --> 00:29:46,880 Speaker 5: you know, particularly significant moves in the share price. 607 00:29:47,640 --> 00:29:50,239 Speaker 2: So in the course of prepping for this interview, I 608 00:29:50,360 --> 00:29:54,080 Speaker 2: was doing, you know, some casual research into MODERNA and 609 00:29:54,080 --> 00:29:57,520 Speaker 2: pharma in general, and I stumbled on this article from 610 00:29:57,800 --> 00:30:01,640 Speaker 2: Science I think it was from March twenty twenty, so 611 00:30:02,040 --> 00:30:04,920 Speaker 2: right in the heart of the pandemic, and it opens 612 00:30:05,560 --> 00:30:09,200 Speaker 2: with a discussion of the gartment hype cycle and this 613 00:30:09,360 --> 00:30:11,760 Speaker 2: idea that you know, people get really excited about a 614 00:30:11,760 --> 00:30:15,760 Speaker 2: new technology. You see share prices of these tech companies 615 00:30:15,840 --> 00:30:19,200 Speaker 2: go through the roof, and then there's some adjustment process 616 00:30:19,240 --> 00:30:22,120 Speaker 2: or reality kind of sets in the shar's fall, and 617 00:30:22,160 --> 00:30:25,440 Speaker 2: then slowly there's a recovery as people kind of enter 618 00:30:25,680 --> 00:30:30,840 Speaker 2: realistic productivity and use of these new technologies. And looking 619 00:30:30,880 --> 00:30:34,320 Speaker 2: at the MODERNA share price since March of twenty twenty, 620 00:30:34,800 --> 00:30:38,200 Speaker 2: it really does look like a gartment hype cycle. Like 621 00:30:38,200 --> 00:30:41,120 Speaker 2: if you're going to choose a textbook example, it's kind 622 00:30:41,160 --> 00:30:43,520 Speaker 2: of this, So I guess my question is, like, how 623 00:30:43,560 --> 00:30:48,720 Speaker 2: do you balance people getting really enthusiastic about new technological 624 00:30:48,800 --> 00:30:53,280 Speaker 2: breakthroughs and all these new treatments we have in the pipeline. 625 00:30:53,360 --> 00:30:55,840 Speaker 2: I mean, I don't think you're working on this specifically, 626 00:30:55,920 --> 00:30:59,320 Speaker 2: but GLP one weight loss drugs are obviously something that's 627 00:30:59,360 --> 00:31:02,360 Speaker 2: kind of burst in to the public consciousness recently. How 628 00:31:02,360 --> 00:31:07,680 Speaker 2: do you balance that excitement and the hype versus like 629 00:31:07,760 --> 00:31:11,680 Speaker 2: the reality of putting these in production and again, going 630 00:31:11,720 --> 00:31:14,479 Speaker 2: back to the timelines that you were discussing the idea 631 00:31:14,560 --> 00:31:17,840 Speaker 2: of long term investment, like, don't get too excited. It's 632 00:31:17,840 --> 00:31:20,080 Speaker 2: going to take a while for these to enter the market, 633 00:31:20,120 --> 00:31:22,680 Speaker 2: and then it's going to potentially take even longer for 634 00:31:22,760 --> 00:31:25,440 Speaker 2: them to filter through in an efficient way. 635 00:31:26,040 --> 00:31:29,960 Speaker 5: I think in those cases, I don't know every single case, 636 00:31:30,800 --> 00:31:33,040 Speaker 5: but I'm a little closer to the Maderna case. Let's say, 637 00:31:33,640 --> 00:31:36,360 Speaker 5: I think it shows the art of the possible, and 638 00:31:36,400 --> 00:31:40,440 Speaker 5: I think people understand what could be from Maderna. And 639 00:31:40,480 --> 00:31:42,400 Speaker 5: to your point, maybe there's a little over exuberance at 640 00:31:42,400 --> 00:31:44,680 Speaker 5: a particular period and time, and I think that's where 641 00:31:44,920 --> 00:31:47,320 Speaker 5: I go to what we should be doing, which is 642 00:31:47,400 --> 00:31:50,320 Speaker 5: to not tell people that that's still not a real 643 00:31:50,480 --> 00:31:54,520 Speaker 5: possibility someday. Well, let's go through the timeline, let's go 644 00:31:54,600 --> 00:31:57,040 Speaker 5: through the risks and opportunities, and let's walk it through 645 00:31:57,560 --> 00:31:59,680 Speaker 5: our you know, as best to our ability in a 646 00:32:00,080 --> 00:32:00,720 Speaker 5: public way. 647 00:32:00,880 --> 00:32:02,560 Speaker 4: Here's what we believe and what. 648 00:32:02,480 --> 00:32:06,640 Speaker 5: Could happen when and after that, investors have to model 649 00:32:06,680 --> 00:32:09,080 Speaker 5: their own cashlowds. That's what a stock price is is 650 00:32:09,160 --> 00:32:11,520 Speaker 5: ultimately what they think the company's worth from. 651 00:32:11,360 --> 00:32:14,760 Speaker 4: A cashloaw perspective. So I think it's a delicate. 652 00:32:14,440 --> 00:32:18,680 Speaker 5: Balance of we still believe what MODERNA can be and 653 00:32:18,960 --> 00:32:21,640 Speaker 5: it should be someday in terms of being able to 654 00:32:21,640 --> 00:32:24,760 Speaker 5: solve so many therapeutic areas as a platform company that 655 00:32:24,840 --> 00:32:27,560 Speaker 5: can run the same technology through a manufacturing plant, and 656 00:32:27,600 --> 00:32:30,040 Speaker 5: so therefore the marginal cost of arguing with drugs should 657 00:32:30,080 --> 00:32:31,360 Speaker 5: go down substantially. 658 00:32:32,360 --> 00:32:33,840 Speaker 4: But there's a timeline for that. 659 00:32:33,920 --> 00:32:36,360 Speaker 5: There are regulators, and there's a timeline, and there's only 660 00:32:36,400 --> 00:32:38,880 Speaker 5: so much in development as expensive, and so we try 661 00:32:38,920 --> 00:32:42,440 Speaker 5: to be as transparent as possible with that, And I 662 00:32:42,480 --> 00:32:44,600 Speaker 5: don't know, I guess that's my belief is we sh 663 00:32:44,600 --> 00:32:47,320 Speaker 5: just to always make sure people understand what could happen someday, 664 00:32:47,480 --> 00:32:50,800 Speaker 5: but also give them the best assumptions possible. 665 00:32:50,920 --> 00:32:53,480 Speaker 4: To the best of your ability over the relative near term. 666 00:32:54,400 --> 00:32:57,239 Speaker 3: Maderna is a according to the Bloomberg right now, I'm 667 00:32:57,280 --> 00:33:01,000 Speaker 3: looking at a thirty seven billion dollar company. But obviously 668 00:33:01,360 --> 00:33:06,240 Speaker 3: this sort of accelerated development of the COVID vaccine, allowing 669 00:33:06,320 --> 00:33:09,080 Speaker 3: life to get back to normal in a maybe a 670 00:33:09,080 --> 00:33:12,080 Speaker 3: period of time that was much shorter than people expected. 671 00:33:12,320 --> 00:33:16,400 Speaker 3: You know, obviously orders of magnitude more valuable to the 672 00:33:16,400 --> 00:33:20,200 Speaker 3: global economy than perhaps what Maderna specifically accrued. And I 673 00:33:20,200 --> 00:33:23,480 Speaker 3: guess that's why you know, we had Operation warp Speed. 674 00:33:23,840 --> 00:33:26,360 Speaker 3: It certainly seems like in theory you could say the 675 00:33:26,400 --> 00:33:31,160 Speaker 3: same thing about other vaccines, other pharma products that are 676 00:33:31,240 --> 00:33:33,320 Speaker 3: in the works. You know, I don't know how much 677 00:33:33,360 --> 00:33:35,880 Speaker 3: money is lost to the flu every year, but it 678 00:33:35,880 --> 00:33:38,080 Speaker 3: would be probably very great for the economy if no 679 00:33:38,120 --> 00:33:40,680 Speaker 3: one got the flu anymore, or colds or any other 680 00:33:40,760 --> 00:33:44,800 Speaker 3: sort of sicknesses that disrupted our life. Do you think 681 00:33:45,040 --> 00:33:47,840 Speaker 3: like I've been a little surprised, you know that after 682 00:33:48,120 --> 00:33:53,440 Speaker 3: the Operation Warp Speed experience, we haven't seen more announcements 683 00:33:53,480 --> 00:33:55,920 Speaker 3: like hey, let's do an operation warp speed for X 684 00:33:56,000 --> 00:33:57,840 Speaker 3: or Y, or maybe they have been and I just 685 00:33:58,160 --> 00:34:01,640 Speaker 3: missed the stories like have you seen any follow up 686 00:34:01,680 --> 00:34:05,240 Speaker 3: on like, Hey, this model did something powerful, Let's do 687 00:34:05,320 --> 00:34:08,560 Speaker 3: it again, let's derisk it, Let's have the government step 688 00:34:08,600 --> 00:34:12,319 Speaker 3: in with this investment and guaranteed purchase agreements. Like have 689 00:34:12,440 --> 00:34:16,120 Speaker 3: people taken lessons from Operation Warp Speed and applied it 690 00:34:16,160 --> 00:34:17,560 Speaker 3: potentially to other areas? 691 00:34:18,440 --> 00:34:21,400 Speaker 5: I think you see some minor examples of that. But 692 00:34:21,440 --> 00:34:26,000 Speaker 5: I also just think that COVID was such a significant 693 00:34:26,080 --> 00:34:29,759 Speaker 5: event that affected the entire global population that it warranted 694 00:34:30,120 --> 00:34:33,000 Speaker 5: both you know, resources from a time perspective as well 695 00:34:33,040 --> 00:34:35,520 Speaker 5: as money perspective. And that's not to say that these 696 00:34:35,560 --> 00:34:38,520 Speaker 5: other ones don't, but it just it was a crisis. 697 00:34:38,600 --> 00:34:42,960 Speaker 5: And so you know, there are areas in oncology that 698 00:34:43,040 --> 00:34:44,840 Speaker 5: I think there's additional funding going behind. 699 00:34:44,920 --> 00:34:47,759 Speaker 4: I think people learning. Okay, rare disease, I hear a 700 00:34:47,760 --> 00:34:48,160 Speaker 4: lot of talk. 701 00:34:48,200 --> 00:34:50,480 Speaker 5: Again, I am not a scientist, I am not a regulator, 702 00:34:51,080 --> 00:34:53,560 Speaker 5: So take it with a grain of salt. But rare 703 00:34:53,560 --> 00:34:57,239 Speaker 5: disease as an example, it's rare by nature, so it's 704 00:34:57,280 --> 00:35:02,719 Speaker 5: difficult to say it's difficult to actually get enough patients 705 00:35:02,760 --> 00:35:08,400 Speaker 5: in data to progress fast because of the regulatory processes, 706 00:35:08,440 --> 00:35:10,920 Speaker 5: and I think the regulators acknowledge that and say, hey, 707 00:35:10,920 --> 00:35:12,520 Speaker 5: if I only have I'm going to make it up 708 00:35:12,560 --> 00:35:15,759 Speaker 5: one hundred patients in the United States. This might take 709 00:35:15,800 --> 00:35:18,440 Speaker 5: ten years, but I can already tell in two years 710 00:35:18,440 --> 00:35:21,440 Speaker 5: in a phase one trial it's making a significant impact 711 00:35:21,560 --> 00:35:25,839 Speaker 5: on fifteen patients. And these are life threatening diseases. It's 712 00:35:25,840 --> 00:35:26,919 Speaker 5: worth taking the risk. 713 00:35:27,440 --> 00:35:29,160 Speaker 4: So it might not be at. 714 00:35:29,040 --> 00:35:34,480 Speaker 6: The same speed and emphasism as operation warp speed, but 715 00:35:34,520 --> 00:35:37,000 Speaker 6: I have seen a couple areas in oncology and rare disease, 716 00:35:37,040 --> 00:35:40,600 Speaker 6: and maybe that's quite honestly, that's where I am personally 717 00:35:40,600 --> 00:35:43,960 Speaker 6: spending time, so I see those things, and maybe it's 718 00:35:43,960 --> 00:35:46,560 Speaker 6: happening in other areas, but I'm just not as knowledgeable 719 00:35:46,560 --> 00:35:48,120 Speaker 6: as all other therapeutic areas. 720 00:35:48,120 --> 00:35:49,520 Speaker 5: But I do see it a little bit more in 721 00:35:49,560 --> 00:35:52,840 Speaker 5: oncology and rare disease. Again, not the same as operation 722 00:35:52,920 --> 00:35:55,080 Speaker 5: warp speed, but I have seen it change people's minds 723 00:35:55,120 --> 00:35:56,359 Speaker 5: and perspectives a little bit. 724 00:35:57,120 --> 00:36:00,239 Speaker 2: I wanted to ask an operational question, which is how 725 00:36:00,280 --> 00:36:04,400 Speaker 2: important is distribution to the pharma business. And one of 726 00:36:04,400 --> 00:36:07,600 Speaker 2: the reasons I ask is because we recorded an episode 727 00:36:07,640 --> 00:36:11,440 Speaker 2: with the Celsius CEO and energy drinks are clearly a 728 00:36:11,600 --> 00:36:15,239 Speaker 2: very different business to pharma, but one thing maybe they 729 00:36:15,239 --> 00:36:17,640 Speaker 2: have in common is that a lot of your success 730 00:36:18,120 --> 00:36:22,080 Speaker 2: depends on actually getting into stores. And obviously, with medicines, 731 00:36:22,120 --> 00:36:24,160 Speaker 2: we are not talking about getting into stores. We're talking 732 00:36:24,160 --> 00:36:29,800 Speaker 2: about getting into hospitals and pharmacies and doctors' offices, and there, 733 00:36:29,960 --> 00:36:33,759 Speaker 2: I imagine you have to face some pretty stiff competition 734 00:36:34,440 --> 00:36:39,200 Speaker 2: from competitors like Pfizer or a Glaxo Smith Klein. So 735 00:36:39,280 --> 00:36:42,120 Speaker 2: how important is that and how do you how does 736 00:36:42,120 --> 00:36:44,839 Speaker 2: that process actually work? What are the discussions like when 737 00:36:44,880 --> 00:36:45,840 Speaker 2: it comes to distribution. 738 00:36:46,440 --> 00:36:49,280 Speaker 4: Yeah, I would say I think distribution is very important. 739 00:36:49,920 --> 00:36:53,279 Speaker 5: I think there are other important factors in terms of 740 00:36:53,320 --> 00:36:57,560 Speaker 5: making sure that medication reaches a patient, but distribution, I mean, 741 00:36:57,800 --> 00:37:00,080 Speaker 5: when I think about it, number one, it's got to 742 00:37:00,160 --> 00:37:02,719 Speaker 5: be there at the right time. So take walking into 743 00:37:02,719 --> 00:37:06,040 Speaker 5: CBS and wanting a flu shot. If CBS does not 744 00:37:06,120 --> 00:37:08,719 Speaker 5: have the flu shot available, there's a chance that you 745 00:37:08,760 --> 00:37:11,759 Speaker 5: might not go back for it. And so the importance 746 00:37:11,760 --> 00:37:14,160 Speaker 5: of being having the supply in the market when a 747 00:37:14,200 --> 00:37:17,719 Speaker 5: patient wants and needs it is extremely important, and distribution plays. 748 00:37:17,440 --> 00:37:17,800 Speaker 4: A role in that. 749 00:37:18,440 --> 00:37:20,239 Speaker 5: There's also many different things that you have to work 750 00:37:20,239 --> 00:37:24,280 Speaker 5: through in terms of storage. So some products are required 751 00:37:24,320 --> 00:37:27,360 Speaker 5: to be refrigerator stable, some are required to be frozen 752 00:37:27,400 --> 00:37:29,800 Speaker 5: at a certain temperature, some are required to be frozen 753 00:37:29,880 --> 00:37:31,759 Speaker 5: at a very cold temperature, and making sure that the 754 00:37:31,800 --> 00:37:36,000 Speaker 5: distribution network has that as well. So the conversation largely 755 00:37:36,080 --> 00:37:38,080 Speaker 5: revolves around that, what can they do to make sure 756 00:37:38,080 --> 00:37:40,560 Speaker 5: that we have the right amount of products in the 757 00:37:40,680 --> 00:37:43,320 Speaker 5: right channels and buy channels for our industry that means 758 00:37:43,400 --> 00:37:47,880 Speaker 5: pharmacies and or doctor's offices, and there's other places to 759 00:37:47,880 --> 00:37:48,879 Speaker 5: put it as well, you. 760 00:37:48,800 --> 00:37:52,280 Speaker 4: Know, but that's largely what that conversation does. And I would. 761 00:37:52,080 --> 00:37:56,360 Speaker 7: Say there is some differentiation in the marketplace from a 762 00:37:56,400 --> 00:38:00,960 Speaker 7: competitive standpoint, but I wouldn't say different Distribution specifically is 763 00:38:01,000 --> 00:38:05,080 Speaker 7: the number one variable for a differentiation between competition. 764 00:38:05,640 --> 00:38:10,080 Speaker 3: Tracy mentioned earlier. But the hot thing, it seems inform 765 00:38:10,360 --> 00:38:13,120 Speaker 3: right now that people are really excited about is gop 766 00:38:13,280 --> 00:38:17,640 Speaker 3: one drugs and weight loss, and if a company has 767 00:38:17,680 --> 00:38:21,160 Speaker 3: something in that category that investors get really excited and 768 00:38:21,440 --> 00:38:25,680 Speaker 3: bid up the stock. You know, imagine things go in 769 00:38:25,719 --> 00:38:28,040 Speaker 3: and out of style at various times, and people are 770 00:38:28,080 --> 00:38:32,279 Speaker 3: really excited about one particular category. Do you feel that 771 00:38:32,520 --> 00:38:34,960 Speaker 3: pressure that is like, Okay, this is the hot thing 772 00:38:35,080 --> 00:38:38,280 Speaker 3: right now weight loss, and we've you know, suppressed people's 773 00:38:38,280 --> 00:38:41,880 Speaker 3: appetite with an injection. Do you feel that pressure and 774 00:38:41,920 --> 00:38:44,480 Speaker 3: does that come from investors? Like are you playing in 775 00:38:44,520 --> 00:38:46,960 Speaker 3: the space? Do one of your forty products? Is it 776 00:38:47,040 --> 00:38:50,799 Speaker 3: going to be potentially related to this category? And I'm curious, like, 777 00:38:50,880 --> 00:38:53,359 Speaker 3: you know, you mentioned that sort of two way conversation. 778 00:38:54,040 --> 00:38:56,799 Speaker 3: You're telling investors about your pipeline, they're telling you what 779 00:38:56,840 --> 00:38:59,479 Speaker 3: they expect. Does this sort of flavor of the month 780 00:38:59,560 --> 00:39:02,120 Speaker 3: or flavor of the year when it comes to what's 781 00:39:02,160 --> 00:39:04,560 Speaker 3: hot in drugs play into those conversations? 782 00:39:05,400 --> 00:39:07,799 Speaker 4: Not really, not for us, not from what I've heard 783 00:39:07,840 --> 00:39:08,640 Speaker 4: from investors. 784 00:39:09,120 --> 00:39:11,960 Speaker 5: I have seen it in other industries for sure, where 785 00:39:12,239 --> 00:39:15,200 Speaker 5: and maybe it's just because there's a hot new product 786 00:39:15,239 --> 00:39:18,120 Speaker 5: that is really core and central, that could be core 787 00:39:18,200 --> 00:39:21,640 Speaker 5: and central to somebody's strategy, but they're missing it GLP 788 00:39:22,280 --> 00:39:24,840 Speaker 5: versus what we've laid out is not core and central 789 00:39:24,880 --> 00:39:27,239 Speaker 5: to our strategy. And so therefore investors understand that and 790 00:39:27,360 --> 00:39:29,400 Speaker 5: quite frankly, rarely. 791 00:39:29,040 --> 00:39:31,239 Speaker 4: Ask about it. Okay, we're in the same yeah, so 792 00:39:31,600 --> 00:39:33,080 Speaker 4: just not as applicable to our company. 793 00:39:33,640 --> 00:39:37,200 Speaker 2: You worked at GE for a long time before going 794 00:39:37,239 --> 00:39:40,040 Speaker 2: on to Motejarna. I think there was another company in between. 795 00:39:40,200 --> 00:39:43,080 Speaker 2: But one thing I'm really curious about is are there 796 00:39:43,160 --> 00:39:49,120 Speaker 2: overlaps between pharma and something like the aircraft business. I 797 00:39:49,120 --> 00:39:51,680 Speaker 2: have to imagine that both of those industries have really 798 00:39:51,800 --> 00:39:54,759 Speaker 2: long lead times that you have to manage, and as 799 00:39:54,800 --> 00:39:57,920 Speaker 2: part of that, you also have to manage investor expectations. 800 00:39:58,640 --> 00:40:00,440 Speaker 4: They are so similar. 801 00:40:01,880 --> 00:40:04,959 Speaker 5: So let me paint the aviation business that I worked 802 00:40:05,000 --> 00:40:07,360 Speaker 5: in for GE, which was I was in the commercial 803 00:40:07,360 --> 00:40:10,560 Speaker 5: engines division, Commercial Engines and Services. So think of you 804 00:40:10,600 --> 00:40:13,920 Speaker 5: know the seven three seven maps, a partnership with a 805 00:40:13,960 --> 00:40:17,600 Speaker 5: company out of France and GE called CFM. Is the 806 00:40:17,800 --> 00:40:20,480 Speaker 5: is the engine on that aircraft? And so when I 807 00:40:20,520 --> 00:40:24,799 Speaker 5: was a CFO there, you're making bets on product families 808 00:40:25,040 --> 00:40:29,279 Speaker 5: that will be on aircraft for literally forty years. And 809 00:40:29,320 --> 00:40:33,720 Speaker 5: these are substantial investments. We're talking two three billion dollars 810 00:40:33,760 --> 00:40:35,239 Speaker 5: for a company to invest. 811 00:40:34,920 --> 00:40:37,400 Speaker 4: In, and you have to make the right bet. Are 812 00:40:37,440 --> 00:40:38,240 Speaker 4: you on the right. 813 00:40:38,120 --> 00:40:40,120 Speaker 5: Aircraft because you know, you can put an engine on 814 00:40:40,360 --> 00:40:42,160 Speaker 5: a bad aircraft and your engine might be great, but 815 00:40:42,160 --> 00:40:44,880 Speaker 5: if nobody buys aircraft, it's irrelevant. So not only do 816 00:40:44,920 --> 00:40:46,480 Speaker 5: you need to make the best engine, you need to 817 00:40:46,480 --> 00:40:48,520 Speaker 5: put it on the right aircraft, people need to buy it, 818 00:40:48,560 --> 00:40:50,640 Speaker 5: and then you need to obviously do everything else well. 819 00:40:50,440 --> 00:40:52,480 Speaker 5: From an execution standpoint. 820 00:40:52,640 --> 00:40:53,640 Speaker 4: That is no different here. 821 00:40:53,760 --> 00:40:56,880 Speaker 5: I mean, we are making you know, I mentioned our 822 00:40:57,040 --> 00:41:00,760 Speaker 5: RSV product as an example, thirty seven dollars in patients. 823 00:41:00,760 --> 00:41:03,160 Speaker 5: It's in the hundreds of millions of dollars from an 824 00:41:03,200 --> 00:41:04,239 Speaker 5: investment perspective. 825 00:41:05,080 --> 00:41:06,840 Speaker 4: But once it's ready, and if it's there. 826 00:41:06,880 --> 00:41:10,600 Speaker 5: You know that rspeed vac scene probably won't be tweaked 827 00:41:10,640 --> 00:41:13,439 Speaker 5: too much. Maybe a little bit of tweaking over time, but. 828 00:41:13,640 --> 00:41:16,279 Speaker 4: We've just cleared a high barrier of entry. Where as 829 00:41:16,320 --> 00:41:19,680 Speaker 4: of right now there's only two competitors, and in the aviation. 830 00:41:19,360 --> 00:41:23,720 Speaker 5: Space there's there's largely three competitors. So they're very similar 831 00:41:23,800 --> 00:41:25,680 Speaker 5: and so the funding. So let's just give an example, 832 00:41:25,760 --> 00:41:28,880 Speaker 5: maybe give you a specific example. When I was at Aviation, 833 00:41:29,000 --> 00:41:30,880 Speaker 5: you think through that three billion dollar program, and we 834 00:41:31,040 --> 00:41:34,680 Speaker 5: had what we called risk and revenue share partners, which 835 00:41:34,760 --> 00:41:36,640 Speaker 5: was somebody to say, hey, we can't invest in six 836 00:41:36,640 --> 00:41:38,960 Speaker 5: product families times three billion dollars each. We're going to 837 00:41:39,000 --> 00:41:40,960 Speaker 5: have to have some partners that they'll make part of 838 00:41:41,000 --> 00:41:43,000 Speaker 5: the engine and they'll help invest in the technology and 839 00:41:43,040 --> 00:41:45,680 Speaker 5: they can share in the commercial rewards. That can be 840 00:41:45,800 --> 00:41:50,040 Speaker 5: very similar in pharmabiotech. So I mentioned Mark in our partnership. 841 00:41:50,760 --> 00:41:52,920 Speaker 5: They funded two hundred and fifty million dollars back in 842 00:41:52,960 --> 00:41:56,839 Speaker 5: twenty sixteen and additional moneys since thereafter, and. 843 00:41:56,760 --> 00:41:59,360 Speaker 4: They owned fifty percent of that program. So when you're. 844 00:41:59,200 --> 00:42:03,600 Speaker 5: Thinking about pulling together this entire pipeline across many different 845 00:42:03,640 --> 00:42:06,240 Speaker 5: therapeutic areas and they all cost a lot of money 846 00:42:06,280 --> 00:42:09,640 Speaker 5: to develop, you need partnerships, and then you know that 847 00:42:09,719 --> 00:42:11,560 Speaker 5: that partnership can provide more than just money. 848 00:42:11,760 --> 00:42:13,680 Speaker 4: In the case of Merk, they are great from a 849 00:42:13,680 --> 00:42:14,560 Speaker 4: commercial perspective. 850 00:42:14,560 --> 00:42:17,200 Speaker 5: They sell the leading oncology drug and the planet, and 851 00:42:17,239 --> 00:42:19,239 Speaker 5: the same in the aviation plant world. You've got to 852 00:42:19,320 --> 00:42:21,160 Speaker 5: have people that might make the best part of the 853 00:42:21,200 --> 00:42:24,719 Speaker 5: engine that you're talking about to improve fuel consumption. So 854 00:42:24,760 --> 00:42:27,040 Speaker 5: they're very similar models one that I think about quite 855 00:42:27,040 --> 00:42:29,160 Speaker 5: a bit. And on top of that, maybe the last 856 00:42:29,200 --> 00:42:32,320 Speaker 5: thing I'd say is they're both highly regulated. I already 857 00:42:32,360 --> 00:42:35,520 Speaker 5: mentioned the biotech space, but aviation, as you know, the 858 00:42:35,640 --> 00:42:39,200 Speaker 5: FAA and other agencies across the globe highly regulate the 859 00:42:39,239 --> 00:42:41,560 Speaker 5: aviation space to make sure that it is very safe 860 00:42:41,560 --> 00:42:43,440 Speaker 5: to fly aircraft across the globe. 861 00:42:43,600 --> 00:42:45,759 Speaker 3: I just have one last question, and I get you know, 862 00:42:45,840 --> 00:42:49,960 Speaker 3: for a sort of young company, growth company, you know, 863 00:42:50,320 --> 00:42:52,920 Speaker 3: macro may not affect you as it may affect a 864 00:42:53,000 --> 00:42:55,480 Speaker 3: more mature company. But I'm just curious, like, when the 865 00:42:55,560 --> 00:43:00,360 Speaker 3: FED raises rates dramatically, what does that mean for company 866 00:43:00,440 --> 00:43:00,920 Speaker 3: like ours? 867 00:43:01,160 --> 00:43:04,440 Speaker 5: Well, for us, again, we're a bit unique because we 868 00:43:04,480 --> 00:43:06,960 Speaker 5: have thirteen billion dollars solid into it our way and 869 00:43:07,000 --> 00:43:09,160 Speaker 5: maybe how I think about it for other companies ways, 870 00:43:09,160 --> 00:43:12,120 Speaker 5: but that might not have be fortunate to thirteen billion. 871 00:43:12,920 --> 00:43:16,760 Speaker 5: Thirteen billion we have I forget the exact number invested 872 00:43:16,800 --> 00:43:19,680 Speaker 5: in bonds, but primarily invested in bonds, and so we 873 00:43:19,680 --> 00:43:21,520 Speaker 5: look at duration, We look. 874 00:43:21,360 --> 00:43:23,600 Speaker 4: At you know, what does that investment portfolio want to 875 00:43:23,600 --> 00:43:25,920 Speaker 4: look like. We're not there to make money on that asset. 876 00:43:25,960 --> 00:43:28,960 Speaker 5: We are there to preserve capital to invest in what 877 00:43:29,080 --> 00:43:30,640 Speaker 5: is core to us, which is our R and D 878 00:43:30,719 --> 00:43:33,960 Speaker 5: and everything that we've spoken about today. But we look at, okay, 879 00:43:34,040 --> 00:43:36,360 Speaker 5: what's that mean? And you know, what's the duration we 880 00:43:36,360 --> 00:43:38,600 Speaker 5: should be taking out? Which is a happy problem to 881 00:43:38,680 --> 00:43:42,279 Speaker 5: have for us. I would say, I would say, you know, 882 00:43:42,360 --> 00:43:45,439 Speaker 5: for a company that is sitting on you know, one 883 00:43:45,480 --> 00:43:48,279 Speaker 5: and a half years of cash burn, and you're just 884 00:43:48,280 --> 00:43:50,680 Speaker 5: sitting there saying, Okay, you know, I'm about chech. I'm 885 00:43:50,719 --> 00:43:53,160 Speaker 5: not revenue yet, I'm not revenue generating yet. I've got 886 00:43:53,200 --> 00:43:55,040 Speaker 5: one and a half years of cash burn, you know, 887 00:43:55,160 --> 00:43:57,439 Speaker 5: in terms of cash on my balance sheet? What does 888 00:43:57,440 --> 00:43:59,840 Speaker 5: this mean? And what do I need to do? You know, 889 00:44:00,000 --> 00:44:02,040 Speaker 5: am I going to make it? You know how interest 890 00:44:02,120 --> 00:44:05,360 Speaker 5: rates affect me? Should I reposition myself? 891 00:44:05,440 --> 00:44:08,279 Speaker 4: Do I What do I need from a death perspective? 892 00:44:08,480 --> 00:44:12,240 Speaker 5: You know, it's just such a different animal in terms 893 00:44:12,280 --> 00:44:14,759 Speaker 5: of surviving that time period in a different way. 894 00:44:15,840 --> 00:44:18,920 Speaker 2: All Right, Jamie Mock, CFO of Moderna, thank you so 895 00:44:19,000 --> 00:44:20,920 Speaker 2: much for coming on all thoughts. That was a really 896 00:44:20,960 --> 00:44:24,279 Speaker 2: interesting conversation. I feel like I understand MODERNA now and 897 00:44:24,440 --> 00:44:27,120 Speaker 2: also the role of CFO a little bit better. 898 00:44:27,320 --> 00:44:29,319 Speaker 4: Well, thank you, Tracy angel I really enjoyed it and 899 00:44:29,440 --> 00:44:30,640 Speaker 4: it was a pleasure. Amazing you both. 900 00:44:43,680 --> 00:44:46,799 Speaker 2: So, Joe, that was really interesting and kind of surprisingly 901 00:44:47,120 --> 00:44:49,640 Speaker 2: thematic in a lot of ways. It seemed to touch 902 00:44:49,800 --> 00:44:52,960 Speaker 2: on a bunch of recent things we've been talking about, 903 00:44:53,200 --> 00:44:54,720 Speaker 2: like aviation. 904 00:44:54,800 --> 00:44:56,160 Speaker 3: Mike, Yeah, I wasn't expecting that. 905 00:44:56,360 --> 00:44:59,799 Speaker 2: Yeah, Like distribution, although I take his point that that 906 00:45:00,120 --> 00:45:04,719 Speaker 2: isn't I guess, a main source of competitive differentiation. But 907 00:45:05,080 --> 00:45:06,840 Speaker 2: I'm glad I've finally got the chance to ask a 908 00:45:06,880 --> 00:45:09,040 Speaker 2: CFO what he thinks when he sees the share price 909 00:45:09,080 --> 00:45:10,759 Speaker 2: going down. I always wanted to ask that. 910 00:45:11,000 --> 00:45:14,080 Speaker 3: Yeah, No, I mean I think it's really interesting. I mean, 911 00:45:14,080 --> 00:45:16,400 Speaker 3: at the end of the day, like, right, any company 912 00:45:16,560 --> 00:45:19,960 Speaker 3: can talk about their vision or their roadmap, et cetera, 913 00:45:20,880 --> 00:45:24,960 Speaker 3: But when investors are selling your stock. I think I 914 00:45:25,040 --> 00:45:28,600 Speaker 3: appreciated his fourth rightness that like you have to take 915 00:45:28,640 --> 00:45:31,480 Speaker 3: that seriously on some level, like it seems like there's 916 00:45:31,560 --> 00:45:35,000 Speaker 3: only so far any company can go in terms of 917 00:45:35,360 --> 00:45:39,080 Speaker 3: staying on one path if investors don't like the path. 918 00:45:39,400 --> 00:45:41,960 Speaker 2: Yeah, And just on that note, I also thought it 919 00:45:42,000 --> 00:45:46,520 Speaker 2: was really interesting his discussion of I guess encouraging investors 920 00:45:46,560 --> 00:45:49,640 Speaker 2: to think over the long term, and also the idea 921 00:45:49,640 --> 00:45:52,200 Speaker 2: that everyone has a different definition of what the long 922 00:45:52,280 --> 00:45:55,920 Speaker 2: term actually is. And I suspect those definitions have been 923 00:45:55,960 --> 00:45:58,319 Speaker 2: getting shorter in recent years. But you know, it can 924 00:45:58,400 --> 00:46:01,799 Speaker 2: range for twenty four months to like ten years, And 925 00:46:01,960 --> 00:46:05,640 Speaker 2: how do you actually convince people to stay with the company, 926 00:46:05,719 --> 00:46:10,520 Speaker 2: be excited about the product offering and the pipeline, but 927 00:46:10,719 --> 00:46:15,720 Speaker 2: not get too excited and expect that immediacy for things 928 00:46:15,760 --> 00:46:19,120 Speaker 2: that take a particularly long time to develop. 929 00:46:19,440 --> 00:46:22,440 Speaker 3: Totally, you know, the I was not expecting him to 930 00:46:22,560 --> 00:46:27,440 Speaker 3: like draw those analogies between pharma development and commercial engines, 931 00:46:27,520 --> 00:46:30,440 Speaker 3: but it makes so much sense because obviously you have this, 932 00:46:30,800 --> 00:46:34,880 Speaker 3: you know, this huge runway, no pun intended, and then 933 00:46:35,120 --> 00:46:37,200 Speaker 3: you're locked in for a long time and the product 934 00:46:37,280 --> 00:46:39,879 Speaker 3: isn't going to change after that until you're really taking 935 00:46:39,880 --> 00:46:44,359 Speaker 3: this sort of like extremely long uncertain bet. I also 936 00:46:44,400 --> 00:46:47,200 Speaker 3: really like to description of the processes that they have 937 00:46:47,320 --> 00:46:50,480 Speaker 3: in place for internal capital allocation. You know, you have 938 00:46:50,600 --> 00:46:54,560 Speaker 3: like forty different processes and that like competition element between 939 00:46:54,600 --> 00:46:56,480 Speaker 3: the different subject areas. 940 00:46:56,719 --> 00:46:58,960 Speaker 2: Yeah, absolutely, shall we leave it there. 941 00:46:59,080 --> 00:47:00,359 Speaker 3: Let's leave it there, all right. 942 00:47:00,360 --> 00:47:03,319 Speaker 2: This has been another episode of the Audlots podcast. I'm 943 00:47:03,320 --> 00:47:06,440 Speaker 2: Tracy Alloway. You can follow me at Tracy Alloway and. 944 00:47:06,400 --> 00:47:09,200 Speaker 3: I'm Joe Wisenthal. You can follow me at the Stalwart. 945 00:47:09,480 --> 00:47:13,480 Speaker 3: Follow our producers Kerman Rodriguez at Kerman Arman, Dashel Bennett 946 00:47:13,480 --> 00:47:16,799 Speaker 3: at Dashbot, and Kilbrooks at Kelbrooks. Thank you to our 947 00:47:16,840 --> 00:47:20,280 Speaker 3: producer Moses Ondem from our Oddlots content. Go to Bloomberg 948 00:47:20,320 --> 00:47:23,200 Speaker 3: dot com slash odd Lotshere we have transcripts, a blog, 949 00:47:23,239 --> 00:47:25,640 Speaker 3: and a newsletter, and you can chat about all of 950 00:47:25,640 --> 00:47:29,080 Speaker 3: our episodes with fellow listeners in the discord twenty four 951 00:47:29,080 --> 00:47:31,720 Speaker 3: to seven discord dot gg slash odlock. 952 00:47:32,000 --> 00:47:34,560 Speaker 2: And if you enjoy Oddlots, if you like it when 953 00:47:34,600 --> 00:47:36,799 Speaker 2: we talk to CFOs about what they actually do on 954 00:47:36,840 --> 00:47:39,960 Speaker 2: a daily basis, then please leave us a positive review 955 00:47:40,040 --> 00:47:43,680 Speaker 2: on your favorite podcast platform. And remember, if you are 956 00:47:43,719 --> 00:47:46,319 Speaker 2: a Bloomberg subscriber, you can listen to all of our 957 00:47:46,360 --> 00:47:49,680 Speaker 2: episodes absolutely ad free. All you need to do is 958 00:47:49,719 --> 00:47:53,520 Speaker 2: connect your Bloomberg account to Apple Podcasts. Thanks for listening 959 00:48:10,320 --> 00:48:10,360 Speaker 5: In