1 00:00:03,000 --> 00:00:06,040 Speaker 1: Welcome to have to Blow Your Mind from stop work 2 00:00:06,120 --> 00:00:15,239 Speaker 1: dot Com. Hey, welcome to stept about your Mind. My 3 00:00:15,280 --> 00:00:18,119 Speaker 1: name is Robert Lamb and my name is Christian Sager. 4 00:00:18,360 --> 00:00:21,640 Speaker 1: So I think both of us share a favorite intro 5 00:00:21,800 --> 00:00:25,160 Speaker 1: scene to a movie. We're talking about The Thing John 6 00:00:25,200 --> 00:00:29,320 Speaker 1: Carpenter's remake of The Thing at the beginning. Yeah, not 7 00:00:29,360 --> 00:00:31,040 Speaker 1: the not the recent one from What Was It Like? 8 00:00:32,200 --> 00:00:34,279 Speaker 1: Which also had the dog in it and I and 9 00:00:34,320 --> 00:00:39,480 Speaker 1: I have to admit I enjoyed that sequel prequel remake. Yeah, 10 00:00:39,520 --> 00:00:41,600 Speaker 1: I didn't hate it as much as some other people did. 11 00:00:41,680 --> 00:00:45,600 Speaker 1: But that movie opens with a dog running across an 12 00:00:45,680 --> 00:00:49,680 Speaker 1: Arctic landscape, but the helicopter chasing it, and people shooting 13 00:00:49,720 --> 00:00:51,720 Speaker 1: from the helicopter at the dog, trying to kill this 14 00:00:51,800 --> 00:00:55,120 Speaker 1: dog desperately, and it arrives at an American camp and 15 00:00:55,160 --> 00:00:57,920 Speaker 1: they can't figure out why. I believe they're Norwegian, right, 16 00:00:58,280 --> 00:01:01,360 Speaker 1: people shotting in Norwegian, raging about this dog, trying to 17 00:01:01,400 --> 00:01:04,000 Speaker 1: kill it, and uh, yeah, it's a it's a factless 18 00:01:04,000 --> 00:01:07,240 Speaker 1: opening scene because it's you start with the chase. Everyone's 19 00:01:07,240 --> 00:01:09,640 Speaker 1: interested in a chase, and then it seems so bizarre, 20 00:01:09,720 --> 00:01:12,560 Speaker 1: like what why is this poor innocent dogg Eve, there's 21 00:01:12,600 --> 00:01:14,560 Speaker 1: a point where they aren't They like thrown grenades at 22 00:01:14,600 --> 00:01:18,280 Speaker 1: it from a helicopter. I've seen it. I definitely remember 23 00:01:18,360 --> 00:01:22,319 Speaker 1: the shooting. Yeah yeah, so, Uh. The reason why we're 24 00:01:22,319 --> 00:01:24,959 Speaker 1: bringing this up is because, of course we're big horror 25 00:01:24,959 --> 00:01:28,080 Speaker 1: monster fans here, and what we're gonna talk about today 26 00:01:28,160 --> 00:01:29,960 Speaker 1: is probably the closest thing in real life we have 27 00:01:30,120 --> 00:01:34,480 Speaker 1: to a horrific monster like the Thing, uh that infects 28 00:01:34,520 --> 00:01:37,800 Speaker 1: human bodies and apparently can now infect dog bodies just 29 00:01:37,880 --> 00:01:40,640 Speaker 1: like the Thing did. Yeah, we see a similar situation 30 00:01:40,720 --> 00:01:43,240 Speaker 1: playing out with the guinea worm because in the Thing, 31 00:01:43,280 --> 00:01:48,720 Speaker 1: of course, uh, this parasitic shape shifting organism from another 32 00:01:48,880 --> 00:01:54,080 Speaker 1: world or another string of world has been almost defeated 33 00:01:54,240 --> 00:01:57,279 Speaker 1: at this Norwegian outpost and it's fled to the place 34 00:01:57,400 --> 00:02:00,200 Speaker 1: in this dog and this is it's it's vessel to 35 00:02:00,240 --> 00:02:03,400 Speaker 1: try and reach another place of safety, and they're trying 36 00:02:03,400 --> 00:02:06,720 Speaker 1: to kill it first. Uh. And we we actually see 37 00:02:06,760 --> 00:02:10,200 Speaker 1: this scenario taking place to a certain extent with the game. 38 00:02:10,520 --> 00:02:13,200 Speaker 1: One of my favorite things about this which you covered 39 00:02:13,240 --> 00:02:15,880 Speaker 1: this previously for How Stuff Works now and in a 40 00:02:15,880 --> 00:02:18,959 Speaker 1: short video that you you out there can find both 41 00:02:19,000 --> 00:02:20,880 Speaker 1: on now do How Stuff Works dot com, but also 42 00:02:21,080 --> 00:02:23,920 Speaker 1: on our social media channels we shared it. You did 43 00:02:23,960 --> 00:02:26,040 Speaker 1: an article in a video, and this is sort of 44 00:02:26,080 --> 00:02:29,160 Speaker 1: our deeper dive into that. But you have this great 45 00:02:29,320 --> 00:02:32,080 Speaker 1: sentence in there that I loved. You said, man maybe 46 00:02:32,560 --> 00:02:35,720 Speaker 1: may indeed be the warmest hiding place, but man's best 47 00:02:35,760 --> 00:02:38,680 Speaker 1: friend will do in a pinch. That's that's my favorite 48 00:02:38,680 --> 00:02:42,080 Speaker 1: tagline for this. Well, because man is the warmest hiding 49 00:02:42,080 --> 00:02:45,920 Speaker 1: place is from the thing, Yeah yeah, yeah, And indeed 50 00:02:45,960 --> 00:02:49,000 Speaker 1: that's kind of what's going on here. Yeah. So it 51 00:02:49,040 --> 00:02:54,320 Speaker 1: also reminds me the guinea worm and this it just 52 00:02:54,560 --> 00:02:56,800 Speaker 1: brought up a bunch of horror movie sci fi kind 53 00:02:56,840 --> 00:02:59,799 Speaker 1: of possibilities to me when we started really researching how 54 00:02:59,800 --> 00:03:02,680 Speaker 1: this thing works. Also made me think of Alien three 55 00:03:03,200 --> 00:03:05,320 Speaker 1: uh in in one of the cuts. There's two different 56 00:03:05,320 --> 00:03:07,160 Speaker 1: cuts of that movie, but in one of them, the 57 00:03:07,280 --> 00:03:10,280 Speaker 1: xenomorph infects a dog instead of a human, right, and 58 00:03:10,360 --> 00:03:12,960 Speaker 1: that that is supposed to explain why it takes this 59 00:03:13,120 --> 00:03:18,920 Speaker 1: more Canine the sweeker for like a uh morphology, it 60 00:03:18,960 --> 00:03:23,639 Speaker 1: has a different biology somehow because uh, the parasite grew 61 00:03:23,680 --> 00:03:26,360 Speaker 1: in a dog, uh and burst out of a dog, 62 00:03:26,720 --> 00:03:29,320 Speaker 1: And we are talking today about a parasite that also 63 00:03:29,440 --> 00:03:31,440 Speaker 1: grows in a dog and burst out of it. Although 64 00:03:31,840 --> 00:03:34,120 Speaker 1: from all the research we've done, it doesn't seem like 65 00:03:34,120 --> 00:03:40,080 Speaker 1: there's a ton of real, like journal published science about 66 00:03:40,120 --> 00:03:43,920 Speaker 1: the dog infestation with guinea worms. So we're not quite 67 00:03:43,960 --> 00:03:45,960 Speaker 1: sure actually if the guinea worms that come out of 68 00:03:46,000 --> 00:03:49,720 Speaker 1: these dogs are all that different, uh, physically than they 69 00:03:49,720 --> 00:03:52,880 Speaker 1: are when they come out of human beings. But the 70 00:03:52,880 --> 00:03:57,160 Speaker 1: the process is certainly different. Yeah. Indeed, so let's let's 71 00:03:57,200 --> 00:03:59,440 Speaker 1: back up. We'll just talk for a minute about the 72 00:03:59,560 --> 00:04:02,680 Speaker 1: organism itself and then we'll get more into this human 73 00:04:02,920 --> 00:04:06,560 Speaker 1: versus guinea worm fight. We're talking about the guinea worm 74 00:04:06,840 --> 00:04:12,440 Speaker 1: drachen Kulis medinansis, which is a nematode or round worm uh. 75 00:04:12,480 --> 00:04:16,039 Speaker 1: And we're talking about a pretty ancient critter here, a 76 00:04:16,080 --> 00:04:19,400 Speaker 1: lineage of organisms that that are honed by up to 77 00:04:19,520 --> 00:04:23,120 Speaker 1: eight billion years of evolution. Now that this is the 78 00:04:23,480 --> 00:04:26,159 Speaker 1: actual estimates here very dependent on who's doing the research. 79 00:04:26,680 --> 00:04:32,440 Speaker 1: But OSU zoologist George point Air, who literally wrote the 80 00:04:32,520 --> 00:04:36,640 Speaker 1: book on nematodes uh, says that the oldest known nematodes 81 00:04:36,880 --> 00:04:39,680 Speaker 1: are from around four hundred million years ago. But he 82 00:04:39,760 --> 00:04:42,039 Speaker 1: but he theorizes that they probably date back around a 83 00:04:42,040 --> 00:04:45,080 Speaker 1: billion years, meaning that they'd be be one of the 84 00:04:45,120 --> 00:04:49,279 Speaker 1: oldest of all life forms, emerging before almost all other 85 00:04:49,360 --> 00:04:53,520 Speaker 1: animals and just after bacteria, protozoa and fun guy. Yeah, 86 00:04:53,560 --> 00:04:55,640 Speaker 1: so one thing that I read said that the ancient 87 00:04:55,640 --> 00:04:58,360 Speaker 1: Egyptians were dealing with this we we we know that 88 00:04:58,440 --> 00:05:00,920 Speaker 1: we found it in their in their eatings, and they 89 00:05:00,960 --> 00:05:03,640 Speaker 1: had some terrible treatments for how to deal with what 90 00:05:03,680 --> 00:05:06,960 Speaker 1: we today called guinea worm disease, one of which involved 91 00:05:06,960 --> 00:05:11,000 Speaker 1: eating goat feces. They assumed that eating that would somehow 92 00:05:11,040 --> 00:05:13,000 Speaker 1: make the worm come out. Well, yeah, it was probably 93 00:05:13,080 --> 00:05:15,680 Speaker 1: used in a combination with other elements because, as Joe 94 00:05:15,720 --> 00:05:19,280 Speaker 1: and I explored in the Tears of Ray episode, Uh, 95 00:05:19,360 --> 00:05:21,400 Speaker 1: they dealt with the ancient Egyptian use of honey. They 96 00:05:21,400 --> 00:05:22,840 Speaker 1: had a lot of the us to honey. They used 97 00:05:22,839 --> 00:05:26,840 Speaker 1: honey and wax and a lot of their medicinal treatments. Uh. 98 00:05:26,880 --> 00:05:31,520 Speaker 1: There was one example of crocodile feces being used in contraceptives, 99 00:05:32,000 --> 00:05:34,800 Speaker 1: and nfecs also pops up in traditional Chinese medicine from 100 00:05:34,839 --> 00:05:38,400 Speaker 1: time to time, to say nothing of of modern fecal transplants. 101 00:05:38,400 --> 00:05:40,520 Speaker 1: So I don't want to demonize. Oh, I wouldn't know. 102 00:05:41,760 --> 00:05:44,880 Speaker 1: And and and let's be honest here, like we're while 103 00:05:45,160 --> 00:05:47,839 Speaker 1: we're we're gonna get into it. We're on the verge 104 00:05:47,839 --> 00:05:52,520 Speaker 1: of eradicating the guinea worm, actually, but it's taken us 105 00:05:52,640 --> 00:05:55,320 Speaker 1: as a as a species a very long time to 106 00:05:55,360 --> 00:05:57,120 Speaker 1: kind of figure out how this whole process works and 107 00:05:57,120 --> 00:05:59,960 Speaker 1: how to attack it, because they're they're a hearty adapt 108 00:06:00,040 --> 00:06:04,080 Speaker 1: of organism. Nematodes themselves. You can find them, you can 109 00:06:04,120 --> 00:06:06,960 Speaker 1: find them on mountaintops, you can find cold around deep 110 00:06:06,960 --> 00:06:11,160 Speaker 1: sea thermal vents. So the nematodes as a whole are 111 00:06:11,240 --> 00:06:14,960 Speaker 1: highly successful, and the guinea worm has also managed to 112 00:06:15,240 --> 00:06:19,080 Speaker 1: cling onto its position as a as a human parasite. 113 00:06:19,120 --> 00:06:22,599 Speaker 1: I actually read that nematodes in general may comprise nine 114 00:06:22,880 --> 00:06:26,040 Speaker 1: percent of all life that's on the ocean floor, and 115 00:06:26,080 --> 00:06:29,480 Speaker 1: there may be up to ten million different species overall. 116 00:06:29,839 --> 00:06:31,880 Speaker 1: But when we're talking about the ones that quote unquote 117 00:06:31,920 --> 00:06:36,000 Speaker 1: infect humans, there's only a hundred and thirty eight, Only 118 00:06:36,000 --> 00:06:38,640 Speaker 1: a hundred and thirty eight of the ten million climb 119 00:06:38,640 --> 00:06:41,240 Speaker 1: inside of us and and burst back out in somewhere 120 00:06:41,400 --> 00:06:44,960 Speaker 1: other I'm pretty certain I didn't follow this tangent, but 121 00:06:45,040 --> 00:06:48,440 Speaker 1: as I was researching this and doing some searches. Occasionally 122 00:06:48,680 --> 00:06:51,120 Speaker 1: I forget reach one of those topics where you absolutely 123 00:06:51,160 --> 00:06:55,200 Speaker 1: cannot search it with without Google scholar on because you 124 00:06:55,279 --> 00:06:58,760 Speaker 1: start getting stuff. Yeah yeah, and uh, and this was 125 00:06:58,960 --> 00:07:01,159 Speaker 1: one because I think I found more than a couple 126 00:07:01,200 --> 00:07:06,800 Speaker 1: of instances where people are saying nematodes are actually aliens. Um, 127 00:07:06,839 --> 00:07:08,599 Speaker 1: and you'll find the same thing with like fun Guy, 128 00:07:08,720 --> 00:07:11,800 Speaker 1: I bet that's a topic that our producer, Knowl's other show, 129 00:07:12,120 --> 00:07:15,160 Speaker 1: Uh stuff they don't watch, should probably cover more that 130 00:07:15,280 --> 00:07:20,800 Speaker 1: they might have covered before. The idea that nematodes are aliens. Yeah, okay, 131 00:07:21,240 --> 00:07:24,640 Speaker 1: I'll buy it for now. We've already connected it to 132 00:07:24,640 --> 00:07:26,920 Speaker 1: the movie Alien and the movie The Thing. So from there, 133 00:07:26,960 --> 00:07:28,880 Speaker 1: I mean, logically it has to be abled. All we 134 00:07:28,880 --> 00:07:31,680 Speaker 1: have to do is then connect these ancient aliens to 135 00:07:31,880 --> 00:07:35,240 Speaker 1: the Old Testament. And Uh. The weird thing about these 136 00:07:35,280 --> 00:07:39,560 Speaker 1: about nematodes in particular, is we have entire departments at 137 00:07:39,640 --> 00:07:42,960 Speaker 1: universities that are dedicated to studying these things, but they're 138 00:07:42,960 --> 00:07:46,720 Speaker 1: dedicated to studying how to kill them because of the 139 00:07:47,240 --> 00:07:50,760 Speaker 1: issues like guinea worm disease. And then also a number 140 00:07:50,800 --> 00:07:55,720 Speaker 1: of nematodes are also crop concerns too. Yeah, so you 141 00:07:55,760 --> 00:07:59,760 Speaker 1: have a definite health and uh and food interest in 142 00:08:00,120 --> 00:08:03,520 Speaker 1: eradicating them, not so much studying them and learning from 143 00:08:03,560 --> 00:08:06,520 Speaker 1: them exactly or like where they came from and and 144 00:08:06,560 --> 00:08:09,600 Speaker 1: like what their influences on our ecology. And I immediately 145 00:08:10,040 --> 00:08:13,560 Speaker 1: started thinking about the recent episode we did on mosquito factories, 146 00:08:13,840 --> 00:08:17,520 Speaker 1: and we started reading about how to eradicate an entire 147 00:08:17,680 --> 00:08:20,640 Speaker 1: species like the guinea worm. I thought, well, what's the 148 00:08:20,680 --> 00:08:23,760 Speaker 1: effect going to be on the local ecology? Um? And 149 00:08:23,800 --> 00:08:26,600 Speaker 1: that doesn't seem to be something people are very concerned 150 00:08:26,640 --> 00:08:28,840 Speaker 1: about in this literature. They want to get rid of 151 00:08:28,840 --> 00:08:33,120 Speaker 1: this thing or explore though in this episode you do 152 00:08:33,200 --> 00:08:36,479 Speaker 1: see an unbalancing when you start messing with the organism. 153 00:08:36,480 --> 00:08:41,079 Speaker 1: The organism messes back. One other thing about the ancient 154 00:08:41,160 --> 00:08:42,920 Speaker 1: history of the guinea worm. They show up in the 155 00:08:42,960 --> 00:08:45,679 Speaker 1: Old Testament. That's how old they are, how long we've 156 00:08:45,720 --> 00:08:48,680 Speaker 1: been dealing with them, And they're referred to as fiery 157 00:08:48,840 --> 00:08:51,480 Speaker 1: serpents in there, I would imagine because of the burning 158 00:08:51,520 --> 00:08:54,840 Speaker 1: sensation when they exit the human body. But instead of 159 00:08:54,880 --> 00:08:56,600 Speaker 1: being thought of as a worm, they were thought of 160 00:08:56,640 --> 00:08:59,200 Speaker 1: as a serpent. So all right, that's sort of the 161 00:08:59,320 --> 00:09:02,800 Speaker 1: background history of how long we've been dealing with it, Robert, 162 00:09:02,880 --> 00:09:05,800 Speaker 1: how what's the life cycle of this thing? So like 163 00:09:05,960 --> 00:09:07,720 Speaker 1: let's talk about it as if like this was like 164 00:09:07,920 --> 00:09:10,959 Speaker 1: a xenomorph infection. Okay, so like how's it get in, 165 00:09:11,320 --> 00:09:13,440 Speaker 1: how's it breed, how's it reproduced? And then how's it 166 00:09:13,480 --> 00:09:16,679 Speaker 1: get out? Well, luckily, this one's pretty pretty straightforward. I'm 167 00:09:16,880 --> 00:09:20,560 Speaker 1: always interested in parasites, and I'm especially interested in those 168 00:09:20,600 --> 00:09:22,920 Speaker 1: life cycle charts you always see for them when you 169 00:09:22,920 --> 00:09:25,880 Speaker 1: look them up on CDC or or other sources. Like 170 00:09:25,920 --> 00:09:28,440 Speaker 1: that's that's like a standard graphic in any kind of 171 00:09:28,760 --> 00:09:31,679 Speaker 1: explanation of how these things work. And some of them 172 00:09:31,679 --> 00:09:36,320 Speaker 1: are really byzantine with multiple um you know, with with 173 00:09:36,400 --> 00:09:40,800 Speaker 1: multiple host organisms with different different phases and different branches. 174 00:09:41,440 --> 00:09:44,319 Speaker 1: This one is is a pretty simple circle, although it 175 00:09:44,360 --> 00:09:47,679 Speaker 1: doesn't go directly into human beings, does it. No, it 176 00:09:48,080 --> 00:09:50,720 Speaker 1: basically what will happen. We're gonna start with the water here, 177 00:09:50,760 --> 00:09:54,720 Speaker 1: so you're gonna have some compromised water, and the larva 178 00:09:54,800 --> 00:09:59,280 Speaker 1: have already infected tiny fresh water copa pods. Yeah they're small, 179 00:09:59,320 --> 00:10:00,959 Speaker 1: but they're small, and that we can filter them out. 180 00:10:00,960 --> 00:10:03,040 Speaker 1: We'll talk about that later. There's some strategies for how 181 00:10:03,080 --> 00:10:05,240 Speaker 1: to do such a thing. Yeah, So you you end 182 00:10:05,320 --> 00:10:09,520 Speaker 1: up drinking in unfiltered drinking water that contains the coca pods. 183 00:10:10,000 --> 00:10:11,960 Speaker 1: Then the copa pods wind up in your stomach and 184 00:10:11,960 --> 00:10:16,679 Speaker 1: that's when they the larva breakout of their their previous host. 185 00:10:17,040 --> 00:10:20,360 Speaker 1: Then they tunnel their way through the stomach and intestinal 186 00:10:20,360 --> 00:10:25,280 Speaker 1: walls and they mature and breed inside the human abdominal cavity. 187 00:10:25,360 --> 00:10:28,600 Speaker 1: So they turn your abdominal cavity basically into a sex 188 00:10:28,679 --> 00:10:31,520 Speaker 1: came right, Yeah, And so we're talking about males and 189 00:10:31,800 --> 00:10:35,200 Speaker 1: females because they're breeding, and the female is what's important 190 00:10:35,240 --> 00:10:38,400 Speaker 1: here because that's the the version of the guinea worm 191 00:10:38,480 --> 00:10:40,960 Speaker 1: that makes its way out of your body. Right once, 192 00:10:41,000 --> 00:10:45,120 Speaker 1: once the male has has finished um making sweet nematode 193 00:10:45,200 --> 00:10:49,880 Speaker 1: love inside your abdominal cavity, it dies in your abdominal cavity. Man, 194 00:10:49,960 --> 00:10:51,920 Speaker 1: So it's just all it knows is that copa pod 195 00:10:52,080 --> 00:10:54,320 Speaker 1: is a baby. And then just the inside of our 196 00:10:54,360 --> 00:10:57,240 Speaker 1: abdoms right, that the rest of the universe is m 197 00:10:57,320 --> 00:11:02,040 Speaker 1: is just unknown to the male limato, but the fertilized female, 198 00:11:02,040 --> 00:11:05,160 Speaker 1: because fertilized to this foot point, she migrates to the 199 00:11:05,200 --> 00:11:09,160 Speaker 1: surface of the host skin and they typically surface on 200 00:11:09,200 --> 00:11:12,440 Speaker 1: the lower body, generally on the legs or the feet, 201 00:11:12,480 --> 00:11:16,520 Speaker 1: and they cause a painful, painful blister um. And when 202 00:11:16,559 --> 00:11:20,000 Speaker 1: the host dips this painful blister into the water for 203 00:11:20,040 --> 00:11:24,400 Speaker 1: a little relief, the two generally two foot or longer 204 00:11:24,559 --> 00:11:28,840 Speaker 1: female worm possibly since it's a change in temperature, and 205 00:11:28,960 --> 00:11:33,120 Speaker 1: bursts out into the water where she then excretes her 206 00:11:33,240 --> 00:11:36,120 Speaker 1: larva to begin the cycle into The larva then infests 207 00:11:36,160 --> 00:11:38,880 Speaker 1: copa pods and then someone drinks them in. Yeah. And 208 00:11:38,920 --> 00:11:41,880 Speaker 1: one of the biological facts I read about them as well, 209 00:11:41,920 --> 00:11:47,079 Speaker 1: that again was very strange and stunning, is that apparently, 210 00:11:47,200 --> 00:11:50,920 Speaker 1: compared to the relative body size of a guinea worm, 211 00:11:51,480 --> 00:11:54,800 Speaker 1: the uterus and a female is huge, and that's how 212 00:11:54,840 --> 00:11:58,160 Speaker 1: it can store so many larva and spew them out. 213 00:11:58,520 --> 00:12:01,200 Speaker 1: What it immediately made me think of is a show 214 00:12:01,240 --> 00:12:03,920 Speaker 1: that we've covered on on stuff to blow your mind before, 215 00:12:04,120 --> 00:12:08,040 Speaker 1: the Strain and uh, sometimes the vampires and that will 216 00:12:08,120 --> 00:12:10,520 Speaker 1: just like they're basically the vampires and that if you 217 00:12:10,600 --> 00:12:13,280 Speaker 1: if you haven't seen it, go listen to our podcast episode. 218 00:12:13,280 --> 00:12:16,440 Speaker 1: But it's full of spoilers. Uh. They basically are created 219 00:12:16,679 --> 00:12:20,320 Speaker 1: by by parasitic worms and there's some scenes where the 220 00:12:20,360 --> 00:12:23,440 Speaker 1: vampires just like vomit out these worms like just like 221 00:12:23,920 --> 00:12:27,320 Speaker 1: spew like hundreds of worms out. And that's what the 222 00:12:27,320 --> 00:12:28,920 Speaker 1: guinea worm made me think of. It's like, if you 223 00:12:29,040 --> 00:12:31,559 Speaker 1: were looking at the whole thing with a microscope, it 224 00:12:31,559 --> 00:12:33,599 Speaker 1: would probably be like that. Yeah, if you if you 225 00:12:33,800 --> 00:12:38,120 Speaker 1: dig wormy parasites and monsters, um, the strain is well 226 00:12:38,120 --> 00:12:41,040 Speaker 1: worth checking out. Like, whatever your misgivings may be about 227 00:12:41,080 --> 00:12:43,440 Speaker 1: any of the other elements in the show, I I, 228 00:12:43,840 --> 00:12:48,120 Speaker 1: in my estimation, they're worth putting up with. Yeah, it's yeah. 229 00:12:48,320 --> 00:12:52,520 Speaker 1: I'm currently binge watching the second season and uh I 230 00:12:52,600 --> 00:12:55,400 Speaker 1: keep coming back from the monsters and the worms. All right, well, 231 00:12:55,400 --> 00:12:57,280 Speaker 1: speaking of coming back for the monsters and the worms, 232 00:12:57,400 --> 00:12:59,199 Speaker 1: let's take a quick break, and when we come back, 233 00:12:59,520 --> 00:13:03,880 Speaker 1: we will breakdown how this life cycle affects the human host, 234 00:13:04,320 --> 00:13:06,920 Speaker 1: how it manifests in the form of guinea worm disease. 235 00:13:12,720 --> 00:13:16,200 Speaker 1: All right, we're back. So okay, so we've described how 236 00:13:16,559 --> 00:13:20,680 Speaker 1: the guinea worm infects a human host, how it pops out, 237 00:13:20,760 --> 00:13:23,360 Speaker 1: but what are the what's the impact on us, what's 238 00:13:23,360 --> 00:13:27,520 Speaker 1: the impact on our bodies? And also like human society 239 00:13:27,679 --> 00:13:30,600 Speaker 1: as it's infected by these things. Right, So, the the 240 00:13:30,760 --> 00:13:33,760 Speaker 1: entire human portion of the life cycle here we've discussed 241 00:13:33,760 --> 00:13:36,480 Speaker 1: takes about a year, and after a year that's when 242 00:13:36,679 --> 00:13:39,400 Speaker 1: you begin to experience symptoms as a host. And the 243 00:13:39,440 --> 00:13:46,120 Speaker 1: typical symptoms are fever, itching, nausea, of vomiting, diarrhea, dizziness. 244 00:13:46,760 --> 00:13:50,200 Speaker 1: So you know these can be bad, but this is 245 00:13:50,240 --> 00:13:52,640 Speaker 1: nothing like super crippling at this point, right, right, But 246 00:13:52,720 --> 00:13:55,160 Speaker 1: think about it, like, you have no idea what happened, 247 00:13:55,160 --> 00:13:57,520 Speaker 1: because it's been a year since you drank that, so 248 00:13:57,600 --> 00:13:59,520 Speaker 1: you just all of a sudden start feeling terrible. It 249 00:13:59,559 --> 00:14:02,320 Speaker 1: could be that those are all symptoms of I don't know, 250 00:14:02,559 --> 00:14:06,120 Speaker 1: like having a bad flu, rather than it seems like 251 00:14:06,160 --> 00:14:08,400 Speaker 1: it's harder to put one and two together in terms 252 00:14:08,400 --> 00:14:11,400 Speaker 1: of when you might have picked up the infection. Now, 253 00:14:12,440 --> 00:14:14,800 Speaker 1: if this weren't bad enough, and it's pretty bad already, 254 00:14:15,480 --> 00:14:18,920 Speaker 1: the problem, the real problem here is a secondary bacterial 255 00:14:18,960 --> 00:14:24,360 Speaker 1: infection commonly results in painful disability. They can disrupt the 256 00:14:24,480 --> 00:14:27,600 Speaker 1: person's ability to work, to attend school, to care for 257 00:14:27,640 --> 00:14:30,440 Speaker 1: family members, and according to the Centers for Disease Control 258 00:14:30,560 --> 00:14:34,840 Speaker 1: Prevention UH, this disability typically last eight and a half weeks, 259 00:14:35,120 --> 00:14:37,640 Speaker 1: but it can sometimes prove permanent. So this is where 260 00:14:37,680 --> 00:14:42,120 Speaker 1: we get into the just really horrific aspect of guinea 261 00:14:42,120 --> 00:14:45,680 Speaker 1: worm disease because it takes you out of I mean, 262 00:14:45,720 --> 00:14:47,200 Speaker 1: at least for eight and a half weeks. Can you 263 00:14:47,240 --> 00:14:49,560 Speaker 1: imagine just being being crippled. I'm able to go to 264 00:14:49,600 --> 00:14:53,000 Speaker 1: work there for loved ones, uh, etcetera, for for that 265 00:14:53,040 --> 00:14:56,480 Speaker 1: space of time. Um. And this this is a point 266 00:14:56,520 --> 00:14:58,720 Speaker 1: I really want to hammer home before we dive even 267 00:14:58,760 --> 00:15:03,520 Speaker 1: further into it. The guinea worm disease is currently only 268 00:15:03,560 --> 00:15:07,920 Speaker 1: occurring in the poorest ten percent of the world's population, 269 00:15:08,400 --> 00:15:11,280 Speaker 1: and that's because they don't have access to clean drinking 270 00:15:11,360 --> 00:15:15,920 Speaker 1: water or modern healthcare. Um. So not only is it 271 00:15:15,960 --> 00:15:21,600 Speaker 1: a symptom of poverty of being poor, but itself causes 272 00:15:21,680 --> 00:15:24,320 Speaker 1: poverty through the disability that we're talking about here. If 273 00:15:24,360 --> 00:15:27,720 Speaker 1: you're out, you can't work for eight and a half sorry, yeah, 274 00:15:27,760 --> 00:15:30,280 Speaker 1: eight eight and a half weeks. Uh, Well, that's going 275 00:15:30,320 --> 00:15:34,320 Speaker 1: to impact your livestock you're farming, right, which is how 276 00:15:34,360 --> 00:15:36,680 Speaker 1: most of the people in these areas are making a living. 277 00:15:37,280 --> 00:15:40,200 Speaker 1: And I also want to emphasize on this burning that 278 00:15:40,240 --> 00:15:42,840 Speaker 1: we talked about, right, We mentioned the fiery serpent, So 279 00:15:42,920 --> 00:15:45,240 Speaker 1: it I mean I haven't had this before. But the 280 00:15:45,280 --> 00:15:47,720 Speaker 1: way that it's described as literal burning, as if like 281 00:15:47,800 --> 00:15:51,120 Speaker 1: you're on fire or something which makes you the host 282 00:15:51,280 --> 00:15:53,560 Speaker 1: want to go to the water. You're talking specifically about 283 00:15:53,560 --> 00:15:57,480 Speaker 1: the blister here, Yeah, and the blister of the time 284 00:15:57,680 --> 00:16:00,720 Speaker 1: forms on the lower part of your body. So all 285 00:16:00,760 --> 00:16:03,040 Speaker 1: you have to do is put maybe the blisters on 286 00:16:03,080 --> 00:16:06,280 Speaker 1: your foot, put your foot in some water. Uh. We 287 00:16:06,400 --> 00:16:10,120 Speaker 1: believe that it's because the nematode senses this temperature change 288 00:16:10,120 --> 00:16:12,560 Speaker 1: of the water that's what causes it to burst out. 289 00:16:12,600 --> 00:16:16,120 Speaker 1: I was immediately thinking like, oh, I wonder if like 290 00:16:16,200 --> 00:16:17,800 Speaker 1: one way to do this is just like put your 291 00:16:17,800 --> 00:16:20,360 Speaker 1: foot in like a bucket of ice and in the 292 00:16:20,400 --> 00:16:23,280 Speaker 1: worm will just like come out. But clearly that's not 293 00:16:23,320 --> 00:16:27,520 Speaker 1: the case, because the actual removal of these worms is. Man, 294 00:16:27,680 --> 00:16:29,680 Speaker 1: this is some grizzly stuff. Like this is one of 295 00:16:29,680 --> 00:16:33,200 Speaker 1: those episodes where I get like a little like grossed out. 296 00:16:33,680 --> 00:16:37,320 Speaker 1: To remove the worm, it's not only very painful, it's 297 00:16:37,320 --> 00:16:39,400 Speaker 1: also time consuming. It's not like you can just take 298 00:16:39,440 --> 00:16:41,760 Speaker 1: a pair of tweezers and yank this thing out. It's 299 00:16:41,840 --> 00:16:45,760 Speaker 1: two to three ft long inside your body. Uh. So 300 00:16:45,960 --> 00:16:48,000 Speaker 1: then the other the other problem here is that if 301 00:16:48,040 --> 00:16:51,400 Speaker 1: it breaks during the removal, the remaining part of the 302 00:16:51,440 --> 00:16:55,240 Speaker 1: female worm will withdraw back into the human body degrade, 303 00:16:55,680 --> 00:16:58,120 Speaker 1: and that's going to cause even more pain and swelling. 304 00:16:58,520 --> 00:17:02,480 Speaker 1: It will then spill it's larvae into your tissues, which 305 00:17:02,480 --> 00:17:06,520 Speaker 1: can lead to more infection and even possibly death. So 306 00:17:06,680 --> 00:17:11,640 Speaker 1: here's how they remove these worms. They get the uh 307 00:17:11,960 --> 00:17:14,879 Speaker 1: top end out of the blister, and they wind that 308 00:17:15,040 --> 00:17:18,359 Speaker 1: around a piece of gauze or a small stick, and 309 00:17:18,440 --> 00:17:21,960 Speaker 1: they manually extract it slowly. And when I say slowly, 310 00:17:22,000 --> 00:17:24,360 Speaker 1: I don't mean like an hour or two. It can 311 00:17:24,359 --> 00:17:27,560 Speaker 1: take days or weeks to get one of these things 312 00:17:27,600 --> 00:17:31,439 Speaker 1: out of a human body. And without proper care, the 313 00:17:31,520 --> 00:17:36,560 Speaker 1: warm wound itself can become infected by bacteria like you 314 00:17:36,280 --> 00:17:38,640 Speaker 1: you mentioned before. So you've not only got to worry 315 00:17:38,640 --> 00:17:41,439 Speaker 1: about the bacteria that can possibly happen from it just 316 00:17:41,520 --> 00:17:44,560 Speaker 1: bursting out, but then there's the potential infection that comes 317 00:17:44,600 --> 00:17:46,680 Speaker 1: if it breaks while you're pulling one out, and then 318 00:17:46,720 --> 00:17:51,280 Speaker 1: there's the potential infection of just not having the wound cleaned. Uh. 319 00:17:51,359 --> 00:17:54,199 Speaker 1: So there's a lot of complications. These can result in 320 00:17:54,240 --> 00:18:01,399 Speaker 1: all kinds of post symptoms, boils, lockjaw, sepsis, and more so, 321 00:18:01,440 --> 00:18:06,240 Speaker 1: the disease causes severe disability, so much so that when 322 00:18:06,720 --> 00:18:09,040 Speaker 1: they've people like the Carter Center have done the math 323 00:18:09,160 --> 00:18:12,320 Speaker 1: on this, they've figured out that it's worth millions of 324 00:18:12,359 --> 00:18:16,359 Speaker 1: dollars each year in farm work that isn't done because 325 00:18:16,359 --> 00:18:19,320 Speaker 1: of people that are infected by this. So it's difficult 326 00:18:19,359 --> 00:18:22,720 Speaker 1: to move around because of the pain. Subsequently they can't 327 00:18:22,720 --> 00:18:25,960 Speaker 1: do their work. Uh, it's it's really you know, it 328 00:18:25,960 --> 00:18:28,280 Speaker 1: doesn't kill these people most of the time, but it's 329 00:18:28,320 --> 00:18:32,320 Speaker 1: fairly traumatizing both to their lifestyle and physically, and I 330 00:18:32,320 --> 00:18:35,639 Speaker 1: would imagine mentally. All Right, so let's talk about the 331 00:18:35,680 --> 00:18:39,399 Speaker 1: war on the guinea worm. If you go back to 332 00:18:39,800 --> 00:18:43,600 Speaker 1: the nineteen eighties, um backs the around nineteen eight six, 333 00:18:43,920 --> 00:18:48,480 Speaker 1: you would find a pretty bad situation in terms of 334 00:18:48,680 --> 00:18:52,359 Speaker 1: guinea worm infection. Twenty one African and Asian countries at 335 00:18:52,400 --> 00:18:55,400 Speaker 1: the time we're experiencing a combined at three point five 336 00:18:55,480 --> 00:18:59,800 Speaker 1: million cases of an of guinea worm infection. So this 337 00:19:00,040 --> 00:19:03,080 Speaker 1: E d C launched the guinea worm Eradication Program in 338 00:19:03,160 --> 00:19:08,520 Speaker 1: night and the Carter Foundation soon took the lead. Yeah, 339 00:19:09,080 --> 00:19:11,679 Speaker 1: and we should mention we're here in Atlanta recording the 340 00:19:11,680 --> 00:19:14,360 Speaker 1: Carter Center's just down the road from US I drive 341 00:19:14,440 --> 00:19:16,520 Speaker 1: by it every day on my way to work. And UH, 342 00:19:17,000 --> 00:19:19,560 Speaker 1: in grad school, spent a lot of time over there 343 00:19:19,560 --> 00:19:23,200 Speaker 1: and in the Carter Library, UM because I was studying 344 00:19:24,560 --> 00:19:26,960 Speaker 1: presidency in rhetoric. And one of the things I really 345 00:19:26,960 --> 00:19:28,720 Speaker 1: wanted to mention here, I don't want to be political, 346 00:19:29,200 --> 00:19:35,360 Speaker 1: but Jimmy Carter's post presidency work is absolutely stunning and inspiring. 347 00:19:35,400 --> 00:19:39,080 Speaker 1: Like if every president left office and did like he did, 348 00:19:39,760 --> 00:19:42,720 Speaker 1: I think it would just be like a huge role 349 00:19:42,760 --> 00:19:45,800 Speaker 1: model to people going forward. I think he's been building houses, 350 00:19:46,080 --> 00:19:49,159 Speaker 1: fighting guinea worm. He's even vowed to make sure that 351 00:19:49,200 --> 00:19:52,040 Speaker 1: the last guinea worm dies before he does. And he's 352 00:19:52,080 --> 00:19:54,720 Speaker 1: been diagnosed with cancer in the last like two years, right, 353 00:19:54,760 --> 00:19:57,200 Speaker 1: I think he beat that. He's in remission, I believe, yeah, 354 00:19:57,320 --> 00:20:02,040 Speaker 1: But cancer can't stop him exactly anyone. Um. And And 355 00:20:02,080 --> 00:20:03,760 Speaker 1: I just want to point out to one of the 356 00:20:03,800 --> 00:20:05,880 Speaker 1: things that I learned when I was doing research over there. 357 00:20:06,160 --> 00:20:09,679 Speaker 1: His farewell addressed UH when he left the presidency is 358 00:20:09,680 --> 00:20:13,119 Speaker 1: pretty interesting because he basically spells out all the things 359 00:20:13,119 --> 00:20:16,040 Speaker 1: that he went on to do for forty years after 360 00:20:16,119 --> 00:20:19,520 Speaker 1: he left office. UM or almost forty years but he 361 00:20:19,680 --> 00:20:21,320 Speaker 1: he kind of said, like, these are the things that 362 00:20:21,359 --> 00:20:23,320 Speaker 1: are important to me, and then he goes out and 363 00:20:23,320 --> 00:20:25,960 Speaker 1: he sticks to it, you know, like he's just he's 364 00:20:25,960 --> 00:20:29,480 Speaker 1: a real interesting guy. But without the Carter Center, the 365 00:20:29,840 --> 00:20:34,280 Speaker 1: we wouldn't be as close to eradicating uh, this being 366 00:20:34,440 --> 00:20:37,480 Speaker 1: this this some people call it an alien. Some people 367 00:20:37,480 --> 00:20:41,359 Speaker 1: think it's an alien, the nematode guinea worm from the 368 00:20:41,359 --> 00:20:43,600 Speaker 1: face of the planet. I mean, they've really made it 369 00:20:43,640 --> 00:20:46,600 Speaker 1: their mission and invested millions of dollars in this. Yeah, 370 00:20:46,640 --> 00:20:50,160 Speaker 1: by twenty fifteen, eradication efforts and we'll go into we're 371 00:20:50,200 --> 00:20:51,960 Speaker 1: going to get into some of the specifics of it 372 00:20:52,440 --> 00:20:55,600 Speaker 1: here in a second, but the the overall eradication efforts 373 00:20:55,720 --> 00:21:01,879 Speaker 1: have reduced infections by nine He just yeah, there were 374 00:21:01,920 --> 00:21:06,240 Speaker 1: just twenty two cases in four different countries, and as 375 00:21:06,320 --> 00:21:09,439 Speaker 1: of right now, or at least as of earlier this 376 00:21:09,480 --> 00:21:12,359 Speaker 1: week when I was researching it, only seven cases. It 377 00:21:12,440 --> 00:21:16,120 Speaker 1: popped up in twenty and that's despite the dog thing 378 00:21:16,119 --> 00:21:18,480 Speaker 1: that we're going to talk about later that the twists. Yeah, 379 00:21:18,560 --> 00:21:21,280 Speaker 1: there's still only seven and those four countries, by the way, 380 00:21:21,359 --> 00:21:25,960 Speaker 1: South Sudan, Molly, Chad, and Ethiopia. So I want to 381 00:21:26,000 --> 00:21:28,960 Speaker 1: hammer this home as well. This is considered when when 382 00:21:29,240 --> 00:21:31,800 Speaker 1: it happens, if they are eradicated, it will be the 383 00:21:31,840 --> 00:21:35,280 Speaker 1: biggest medical triumph, one of them in modern history. The 384 00:21:35,280 --> 00:21:39,240 Speaker 1: only thing even close to this is when we ended smallpox. Uh. 385 00:21:39,280 --> 00:21:42,960 Speaker 1: And it's estimated that the Carter Center has averted eighty 386 00:21:43,240 --> 00:21:47,680 Speaker 1: million cases of guinea worm disease with their campaign. So 387 00:21:48,119 --> 00:21:50,720 Speaker 1: I mean that's fantastic. Yeah. I mean when you think 388 00:21:50,720 --> 00:21:54,880 Speaker 1: of the just the collective amount of suffering that has 389 00:21:54,880 --> 00:21:57,960 Speaker 1: been reduced by this effort, it's pretty many. Yeah, there's that. 390 00:21:58,080 --> 00:22:00,360 Speaker 1: And then again there's the part of me that has 391 00:22:00,400 --> 00:22:02,440 Speaker 1: been doing this show for a while and thinks, yeah, 392 00:22:02,480 --> 00:22:05,320 Speaker 1: but what about like we're going to eradicate an entire 393 00:22:05,400 --> 00:22:07,240 Speaker 1: species off the face of the planet. I wonder what 394 00:22:07,320 --> 00:22:10,359 Speaker 1: the results of that are going to be well, which 395 00:22:10,400 --> 00:22:14,320 Speaker 1: we may be seeing now with their entry into canine exactly. 396 00:22:14,840 --> 00:22:17,840 Speaker 1: So some of these key the key tactics involved here 397 00:22:17,880 --> 00:22:20,880 Speaker 1: in fighting ginny worm and the and these uh, these 398 00:22:20,880 --> 00:22:24,840 Speaker 1: tactics come from CDC and the and the Carter Foundation. Uh. 399 00:22:25,160 --> 00:22:28,359 Speaker 1: The big one, of course is managing the drinking water. 400 00:22:28,800 --> 00:22:32,040 Speaker 1: That means making sure that that you have safe drinking 401 00:22:32,040 --> 00:22:36,240 Speaker 1: water sources such as borehole wells and dug wells or 402 00:22:36,320 --> 00:22:39,439 Speaker 1: springs with productive walls around them and caps to prevent 403 00:22:39,520 --> 00:22:43,160 Speaker 1: to prevent infected people with worms emerging from waiting and 404 00:22:43,200 --> 00:22:47,840 Speaker 1: contaminating the water. You want flowing water sources, water treatment 405 00:22:48,280 --> 00:22:52,000 Speaker 1: mesh to filter out those infected coke pods. That's this 406 00:22:52,080 --> 00:22:53,560 Speaker 1: is really one of the huge area. So a lot 407 00:22:53,600 --> 00:22:57,440 Speaker 1: of these efforts have been involved with just managing water sources. 408 00:22:57,440 --> 00:22:59,960 Speaker 1: So I spent all day yesterday researching this for the epoch. 409 00:23:00,040 --> 00:23:03,439 Speaker 1: So and uh, we use a brit of filter, one 410 00:23:03,480 --> 00:23:05,480 Speaker 1: of those like kind of things, you know, you fill 411 00:23:05,600 --> 00:23:08,440 Speaker 1: fill it up in the sink, sits in your fridge filters, 412 00:23:08,520 --> 00:23:10,439 Speaker 1: and then you drink the water. And I drink a 413 00:23:10,480 --> 00:23:13,199 Speaker 1: lot of water during the day while I'm working, and 414 00:23:13,280 --> 00:23:15,280 Speaker 1: I was just pouring it out and just thinking, like 415 00:23:15,680 --> 00:23:18,240 Speaker 1: what what's in here? But like like there's the filter 416 00:23:18,400 --> 00:23:20,320 Speaker 1: on this thing, but I don't know what what's in 417 00:23:20,400 --> 00:23:22,679 Speaker 1: here that I'm drinking and swallowing and getting into me 418 00:23:22,760 --> 00:23:25,439 Speaker 1: right now. And then I thought, you're in You're lucky. 419 00:23:25,520 --> 00:23:28,359 Speaker 1: You're in the first world society. You probably don't have 420 00:23:28,400 --> 00:23:32,280 Speaker 1: to worry about uh drech um kuliasis. Yeah, now on 421 00:23:32,359 --> 00:23:35,760 Speaker 1: the subject of filters, one of the more notable filter 422 00:23:35,880 --> 00:23:40,000 Speaker 1: methods out there is something known as life straw. So 423 00:23:40,240 --> 00:23:43,639 Speaker 1: it was produced by Vestor Guard in cooperation with the 424 00:23:43,640 --> 00:23:47,800 Speaker 1: Carter Foundation. Work started on it and around nineteen and 425 00:23:47,840 --> 00:23:50,439 Speaker 1: this is basically originally they were looking at a cloth 426 00:23:50,600 --> 00:23:54,520 Speaker 1: filter system, but then it evolved into a simple straw 427 00:23:54,680 --> 00:23:59,200 Speaker 1: like it's basically a personal uh water filtration system where 428 00:23:59,200 --> 00:24:00,879 Speaker 1: you you put the strong the water, you suck the 429 00:24:00,920 --> 00:24:03,359 Speaker 1: water up into your mouth and it filters out the 430 00:24:03,359 --> 00:24:07,040 Speaker 1: infected copa pods UM and and they since evolved this 431 00:24:07,080 --> 00:24:09,520 Speaker 1: into a number of different filteration systems like you know, 432 00:24:09,680 --> 00:24:15,399 Speaker 1: family size, larger implementations of it. And I believe the 433 00:24:15,440 --> 00:24:17,480 Speaker 1: stuff you should know even did an episode on the 434 00:24:17,520 --> 00:24:21,960 Speaker 1: Live Strap back in check that out and more about it. 435 00:24:22,000 --> 00:24:25,199 Speaker 1: But it's just one of several different different efforts that 436 00:24:25,240 --> 00:24:27,679 Speaker 1: have been put forth to combat anywhere. I picture it 437 00:24:27,760 --> 00:24:30,359 Speaker 1: is kind of like UM giver have urban mate before, 438 00:24:30,400 --> 00:24:33,600 Speaker 1: and like the traditional way like urban mate is supposed 439 00:24:33,640 --> 00:24:37,280 Speaker 1: to be presented in UM like a specific kind of 440 00:24:37,280 --> 00:24:40,600 Speaker 1: wooden cup and then you take a metal straw and 441 00:24:40,640 --> 00:24:43,960 Speaker 1: it has a filter on the pod. It's a little 442 00:24:44,000 --> 00:24:47,040 Speaker 1: different than green tea. It's it's um, I believe Brazilian 443 00:24:47,240 --> 00:24:50,760 Speaker 1: or maybe maybe Argentineans at all. Oh, it's great stuff. 444 00:24:50,760 --> 00:24:53,320 Speaker 1: I I like it quite a bit. But one year 445 00:24:53,359 --> 00:24:55,360 Speaker 1: my wife got me because I like it. She got 446 00:24:55,359 --> 00:24:58,920 Speaker 1: me the straw and the the cup, the traditional cup 447 00:24:58,960 --> 00:25:01,159 Speaker 1: that you put the stuff in. And that's what I 448 00:25:01,200 --> 00:25:03,000 Speaker 1: think of when I think of the lifestra, although I 449 00:25:03,040 --> 00:25:05,240 Speaker 1: don't think the filter in an urban mate stra is 450 00:25:05,320 --> 00:25:11,040 Speaker 1: quite like powerful enough to get rid of copa pods. 451 00:25:11,080 --> 00:25:15,440 Speaker 1: So on top of filtration, vector control is important health 452 00:25:15,600 --> 00:25:20,800 Speaker 1: education and community mobilization, like just educating people about what 453 00:25:20,960 --> 00:25:24,320 Speaker 1: these things are and where the risks associated with them 454 00:25:24,320 --> 00:25:27,760 Speaker 1: are to be found. Case containment is big. A case 455 00:25:28,240 --> 00:25:31,560 Speaker 1: of guinea worm disease is considered to be contained when, 456 00:25:31,760 --> 00:25:34,240 Speaker 1: first of all, the person is identified within twenty four 457 00:25:34,320 --> 00:25:37,880 Speaker 1: hours of the worm emerging, um the person has not 458 00:25:38,080 --> 00:25:40,960 Speaker 1: entered any water source since the worm has emerged, the 459 00:25:41,040 --> 00:25:44,480 Speaker 1: person receives proper treatment and case management by a local 460 00:25:44,520 --> 00:25:48,280 Speaker 1: health provider, and within seven days of the worm emerging, 461 00:25:48,400 --> 00:25:52,800 Speaker 1: a guinea worm Eradication program supervisor determines that all the 462 00:25:52,840 --> 00:25:55,880 Speaker 1: above criteria have been met in the case is truly 463 00:25:56,240 --> 00:25:59,280 Speaker 1: taken care of. So the thing here that the Carter 464 00:25:59,359 --> 00:26:01,800 Speaker 1: Center is really have to struggle with is that it's 465 00:26:01,880 --> 00:26:04,520 Speaker 1: not about as much of like that they're going around 466 00:26:04,600 --> 00:26:07,560 Speaker 1: like with flamethrowers killing guinea worms right Like, It's not 467 00:26:07,720 --> 00:26:11,480 Speaker 1: like that. It's more about community based intervention where you're 468 00:26:11,600 --> 00:26:14,840 Speaker 1: educating people and changing their behavior in these areas that 469 00:26:14,880 --> 00:26:17,879 Speaker 1: are so heavily affected. So they mainly teach people to 470 00:26:17,920 --> 00:26:21,880 Speaker 1: filter out their water and prevent transmission. They distribute things 471 00:26:21,960 --> 00:26:24,320 Speaker 1: like the life straw we are just speaking of. Especially 472 00:26:24,359 --> 00:26:27,000 Speaker 1: if you have an emerging worm, they want you to 473 00:26:27,080 --> 00:26:29,760 Speaker 1: know the last thing you should do is go near 474 00:26:29,800 --> 00:26:31,960 Speaker 1: water because it's gonna make it worse for everybody else 475 00:26:32,000 --> 00:26:35,240 Speaker 1: in your community. Um, and they have a number of partners. 476 00:26:35,280 --> 00:26:37,800 Speaker 1: I just really want to quickly cover this because it's 477 00:26:37,840 --> 00:26:40,679 Speaker 1: it's it's a huge global effort that's gone into this. 478 00:26:41,080 --> 00:26:44,800 Speaker 1: So the countries that we mentioned before, South Sudan, Molly, Chad, 479 00:26:44,840 --> 00:26:48,760 Speaker 1: and Ethiopia, all their national ministries of health are involved 480 00:26:49,000 --> 00:26:51,960 Speaker 1: and they oversee elimination programs and have the staff that 481 00:26:52,040 --> 00:26:54,479 Speaker 1: kind of go out and interact with the communities. Then 482 00:26:54,520 --> 00:26:58,040 Speaker 1: the World Health Organization is also involved and it certifies 483 00:26:58,119 --> 00:27:01,719 Speaker 1: countries when they're worm free. I'm not quite sure how 484 00:27:01,760 --> 00:27:03,680 Speaker 1: they measure that, but there there's got to be some 485 00:27:03,760 --> 00:27:08,160 Speaker 1: kind of quantification measurement in place. I don't know. They've 486 00:27:08,240 --> 00:27:12,399 Speaker 1: analytics they use UM. And then we've talked about the 487 00:27:12,400 --> 00:27:14,639 Speaker 1: c d C, the u S Centers for Disease Control 488 00:27:14,680 --> 00:27:19,000 Speaker 1: and Prevention also here in Atlanta. UM they provide technical 489 00:27:19,040 --> 00:27:23,159 Speaker 1: assistance identifying the worms on site trying because sometimes worms 490 00:27:23,160 --> 00:27:27,000 Speaker 1: burst out of people's blisters and they're not actually guinea worms. Remember, 491 00:27:27,040 --> 00:27:30,640 Speaker 1: there's all those other nematodes that are capable of infecting you. UM, 492 00:27:30,680 --> 00:27:33,080 Speaker 1: so there's that as well. And then Unit SEF is 493 00:27:33,160 --> 00:27:36,520 Speaker 1: also involved and they assist by providing clean drinking water 494 00:27:36,600 --> 00:27:39,919 Speaker 1: to these communities. A couple of corporations have also been involved, 495 00:27:39,920 --> 00:27:43,760 Speaker 1: and they've donated more than four million dollars of non 496 00:27:43,960 --> 00:27:47,439 Speaker 1: toxic larvae side to kill the copa pods themselves that 497 00:27:47,520 --> 00:27:50,520 Speaker 1: carry the larvae UM. So they're basically like blasting the 498 00:27:50,560 --> 00:27:53,920 Speaker 1: water with this stuff. Uh. And they've also donated nylon 499 00:27:54,280 --> 00:27:57,440 Speaker 1: and then the life straws as well. The corporations with 500 00:27:57,480 --> 00:28:00,280 Speaker 1: those filters to make sure that the risk of disease 501 00:28:00,440 --> 00:28:03,560 Speaker 1: isn't coming from the natural water. Sources so much, and 502 00:28:03,640 --> 00:28:06,919 Speaker 1: this work is so important for the following reason. This 503 00:28:07,000 --> 00:28:10,120 Speaker 1: is a statistic on getting worm disease. If you miss 504 00:28:10,520 --> 00:28:15,040 Speaker 1: just one case, that can lead to eighty more infections 505 00:28:15,080 --> 00:28:17,840 Speaker 1: the following year. Remember it takes a year to just date. 506 00:28:18,040 --> 00:28:21,680 Speaker 1: So you miss one case, worm bursts into the water, 507 00:28:21,920 --> 00:28:25,919 Speaker 1: spews out its larva, somebody goes along and drinks the water, 508 00:28:26,920 --> 00:28:29,399 Speaker 1: and you've got eighty more cases a year later. And 509 00:28:29,440 --> 00:28:31,640 Speaker 1: they don't know that they're infected until a year later 510 00:28:31,720 --> 00:28:34,280 Speaker 1: when they start getting the blisters. It drives home just 511 00:28:34,320 --> 00:28:37,280 Speaker 1: how important the persistence here is. Like the scenario I 512 00:28:37,359 --> 00:28:41,160 Speaker 1: keep imagining, it's like a a really well organized Roman 513 00:28:41,240 --> 00:28:45,480 Speaker 1: legion with their shield walls and and their spears going 514 00:28:45,560 --> 00:28:49,680 Speaker 1: up against like an any human whore, you know. And 515 00:28:49,720 --> 00:28:52,160 Speaker 1: as long as they are persistent, if they keep, they keep, 516 00:28:52,200 --> 00:28:55,600 Speaker 1: they stay disciplined, they stay in formation, and they have 517 00:28:55,720 --> 00:28:58,040 Speaker 1: they keep, they keep their focus on the long fight, 518 00:28:58,400 --> 00:29:01,760 Speaker 1: they are going to persevere a win. Yeah, yeah, yeah. 519 00:29:01,800 --> 00:29:06,480 Speaker 1: And it's and it's again like it's so complicated because 520 00:29:06,480 --> 00:29:09,760 Speaker 1: it involves you know what it is. It involves a 521 00:29:09,760 --> 00:29:15,480 Speaker 1: lot of wicked problems, including economic scale, national boundaries, healthcare, 522 00:29:16,040 --> 00:29:19,320 Speaker 1: all that stuff. Plus education. I'm sure that there's language 523 00:29:19,360 --> 00:29:22,600 Speaker 1: boundaries here that are an issue as well. Uh yeah. 524 00:29:22,680 --> 00:29:24,640 Speaker 1: And then on top of that, as we're going to 525 00:29:24,680 --> 00:29:35,920 Speaker 1: discuss after a quick break, sometimes nature throws you a curveball. Alright, 526 00:29:35,960 --> 00:29:38,600 Speaker 1: we're back. Yeah, And so, as Robert alluded to right 527 00:29:38,600 --> 00:29:41,880 Speaker 1: before a break, uh, this is a case of the 528 00:29:41,920 --> 00:29:47,400 Speaker 1: old Jurassic Park adage. Sometimes life finds a way, uh 529 00:29:47,440 --> 00:29:50,280 Speaker 1: and it and it has. Uh. So it turns out 530 00:29:50,360 --> 00:29:52,600 Speaker 1: that despite all of the work of the Carter Center 531 00:29:52,640 --> 00:29:56,400 Speaker 1: and others trying to eradicate the guinea worm, we have 532 00:29:56,640 --> 00:30:00,320 Speaker 1: just found well not just found, but it's it's just 533 00:30:00,360 --> 00:30:04,640 Speaker 1: been identified as a major problem. They're infecting dogs as 534 00:30:04,640 --> 00:30:07,880 Speaker 1: well as human beings. Now, yeah, I first read about 535 00:30:07,880 --> 00:30:11,000 Speaker 1: this as reported by NPR and the reports they did. 536 00:30:11,080 --> 00:30:13,560 Speaker 1: The worms that have been popping up in dogs and 537 00:30:13,640 --> 00:30:18,320 Speaker 1: chad since since around sometimes to the tune of sixty 538 00:30:18,480 --> 00:30:22,760 Speaker 1: or more parasites per hopes. Okay, let's stop for a 539 00:30:22,760 --> 00:30:25,760 Speaker 1: second and think about that. That is that's the thing 540 00:30:25,960 --> 00:30:28,080 Speaker 1: out of all of this research that just made me 541 00:30:28,440 --> 00:30:33,640 Speaker 1: absolutely go oh my god. Um, because I mean, let's 542 00:30:33,720 --> 00:30:36,200 Speaker 1: let's back up for a second. Each one of these 543 00:30:36,200 --> 00:30:38,920 Speaker 1: worms is two to three ft long or one about 544 00:30:38,960 --> 00:30:41,440 Speaker 1: a meter because it's not a small worm and it's 545 00:30:41,440 --> 00:30:45,600 Speaker 1: not a whole like spaghetti bowl of worms? Did the 546 00:30:45,720 --> 00:30:49,800 Speaker 1: dogs are just choked full of Imagine how painful that 547 00:30:49,880 --> 00:30:53,280 Speaker 1: must be for these poor dogs. And and uh, they're 548 00:30:53,320 --> 00:30:56,440 Speaker 1: just I mean their body mass compared to ours. So 549 00:30:56,640 --> 00:30:58,040 Speaker 1: I think I mentioned this at the top. One of 550 00:30:58,040 --> 00:30:59,600 Speaker 1: the things we haven't been able to figure out from 551 00:30:59,640 --> 00:31:03,200 Speaker 1: the research is do the worms grow at a rate 552 00:31:03,320 --> 00:31:06,800 Speaker 1: comparative to the size of their host? Right? So like 553 00:31:06,880 --> 00:31:10,280 Speaker 1: the like the xenomorm example, right, Like do they are 554 00:31:10,320 --> 00:31:12,680 Speaker 1: they smaller because they're in dogs? I don't know. The 555 00:31:12,720 --> 00:31:15,440 Speaker 1: other thing is, from what we've read so far, only 556 00:31:15,520 --> 00:31:19,760 Speaker 1: one female bursts out of the human host. In this case, 557 00:31:20,040 --> 00:31:24,920 Speaker 1: they're finding sixty worms. This isn't sixty larva, it's sixty worms. 558 00:31:25,400 --> 00:31:29,640 Speaker 1: So it's just absolutely mind blowing. It's it's heartbreaking to 559 00:31:29,640 --> 00:31:32,800 Speaker 1: think about these poor dogs too. Now, that's the important 560 00:31:33,400 --> 00:31:35,120 Speaker 1: I think that to keep in mind too about the 561 00:31:35,480 --> 00:31:38,680 Speaker 1: dogs is that if you've ever if you have traveled 562 00:31:38,840 --> 00:31:41,480 Speaker 1: to other countries, or you have you have family and 563 00:31:41,520 --> 00:31:45,080 Speaker 1: other countries or family origins and other countries, you you 564 00:31:45,120 --> 00:31:49,080 Speaker 1: may realize that the way that dogs are treated in 565 00:31:49,120 --> 00:31:51,760 Speaker 1: the United States. It is different from a lot of 566 00:31:51,800 --> 00:31:54,080 Speaker 1: places in the world, like the care. We treat them 567 00:31:54,120 --> 00:31:58,520 Speaker 1: as as members of our family, and we really spend 568 00:31:58,560 --> 00:32:01,640 Speaker 1: a ridiculous amount of time and energy and money on 569 00:32:01,840 --> 00:32:05,600 Speaker 1: sustaining their health. Oh absolutely, I mean I talk about 570 00:32:05,640 --> 00:32:07,520 Speaker 1: my dogs on the show sometimes. I'm very much a 571 00:32:07,560 --> 00:32:11,520 Speaker 1: dog person. I've got two pit bull mixes, and I 572 00:32:11,520 --> 00:32:14,520 Speaker 1: immediately started thinking about them when I was doing this research, 573 00:32:14,640 --> 00:32:17,120 Speaker 1: just thinking like, oh, I can't imagine if one of 574 00:32:17,160 --> 00:32:20,640 Speaker 1: my dogs was infected with sixty of these worms, you know. 575 00:32:20,920 --> 00:32:23,200 Speaker 1: And but your dogs are like that they stay inside 576 00:32:23,240 --> 00:32:27,120 Speaker 1: and they go outside and they're outside the yard. Yeah. Well, 577 00:32:27,520 --> 00:32:30,240 Speaker 1: in many places in the world, and especially and Chad, 578 00:32:30,320 --> 00:32:33,360 Speaker 1: which is the main country of focus here, the dogs 579 00:32:33,400 --> 00:32:36,600 Speaker 1: are a little more loose, you know. They're they're running 580 00:32:36,600 --> 00:32:38,880 Speaker 1: around there on their own and they come back to 581 00:32:38,920 --> 00:32:41,240 Speaker 1: the house. They're probably not sleeping in the house. They're 582 00:32:41,240 --> 00:32:43,520 Speaker 1: not getting they're not being chained up or restrained, and 583 00:32:43,520 --> 00:32:46,360 Speaker 1: they think that's just how how life is. Yeah. They're 584 00:32:46,360 --> 00:32:50,080 Speaker 1: more like, uh, like part of the farm, right like 585 00:32:50,200 --> 00:32:52,920 Speaker 1: as any other like sort of agricultural animal would be 586 00:32:52,960 --> 00:32:56,040 Speaker 1: on the property. They're they're kept there to protect the crops, 587 00:32:56,120 --> 00:32:58,600 Speaker 1: mainly from baboons. From what I was reading, Yeah, you 588 00:32:58,600 --> 00:33:00,560 Speaker 1: could think of them as all I mean, I hate 589 00:33:00,560 --> 00:33:02,560 Speaker 1: to throw fare all around. You can almost think of 590 00:33:02,600 --> 00:33:04,480 Speaker 1: them as sort of semi farrell because they kind of 591 00:33:04,480 --> 00:33:07,800 Speaker 1: have their own community going on. Um, they don't so 592 00:33:07,920 --> 00:33:15,320 Speaker 1: much as live within human society as along the Yeah, um, yeah, 593 00:33:15,360 --> 00:33:16,680 Speaker 1: I saw a lot of that, you know, Like I 594 00:33:16,680 --> 00:33:19,840 Speaker 1: grew up overseas and um lived in Singapore and traveled 595 00:33:19,840 --> 00:33:22,280 Speaker 1: around Southeast Asia a lot, and I saw a lot 596 00:33:22,320 --> 00:33:26,720 Speaker 1: of stray dogs, um, but not dogs in this sense 597 00:33:26,760 --> 00:33:28,920 Speaker 1: where they're like they're part of the community, like they 598 00:33:28,960 --> 00:33:32,920 Speaker 1: serve a function. Um. So I'm sure like in some 599 00:33:32,960 --> 00:33:35,560 Speaker 1: cases these people are invested in having these dogs on 600 00:33:35,600 --> 00:33:37,640 Speaker 1: their property or keeping them alive. But at the same time, 601 00:33:37,680 --> 00:33:39,800 Speaker 1: they're not building them doghouses. They're taking them to the 602 00:33:39,880 --> 00:33:43,240 Speaker 1: vet and giving them treats and teaching them to sit. Right. 603 00:33:43,280 --> 00:33:47,960 Speaker 1: They probably don't have extensive span neuter programs, right yeah, yeah, 604 00:33:48,040 --> 00:33:50,160 Speaker 1: and that's part of the problem because if if there 605 00:33:50,160 --> 00:33:52,479 Speaker 1: weren't the worms are in the dogs, then what are 606 00:33:52,480 --> 00:33:57,240 Speaker 1: we doing to control the dog population? The dog problem 607 00:33:57,280 --> 00:34:00,160 Speaker 1: that of course has been that is mentioned in with 608 00:34:00,200 --> 00:34:01,880 Speaker 1: the literature, the idea like, well, what if you just 609 00:34:01,960 --> 00:34:04,440 Speaker 1: wiped out all the dogs? Yeah, and that would be 610 00:34:04,800 --> 00:34:09,440 Speaker 1: cost prohibitive and also it's not a great like public relation, 611 00:34:09,520 --> 00:34:12,719 Speaker 1: pretty bad pr move on half of I mean, I 612 00:34:12,760 --> 00:34:15,000 Speaker 1: don't know what organization would be in charge of doing that. 613 00:34:15,040 --> 00:34:17,799 Speaker 1: I suppose it would be one of these nations health ministries, 614 00:34:17,840 --> 00:34:20,919 Speaker 1: but uh, they've actually made it clear like they're not 615 00:34:21,000 --> 00:34:24,319 Speaker 1: going to do that. Euthanizing these dogs would be not 616 00:34:24,440 --> 00:34:28,920 Speaker 1: only would it be ethically a problematic for them, but 617 00:34:29,120 --> 00:34:32,279 Speaker 1: it's also it would be the largest what is called 618 00:34:32,280 --> 00:34:36,879 Speaker 1: a culling project of any animal in history. There's over 619 00:34:37,000 --> 00:34:39,360 Speaker 1: ten thousand of these dogs in these countries, and a 620 00:34:39,480 --> 00:34:42,560 Speaker 1: chat in particular, I believe, so they would have to 621 00:34:42,680 --> 00:34:46,799 Speaker 1: kill ten thousand dogs to eradicate this. And then what 622 00:34:46,920 --> 00:34:48,799 Speaker 1: we're going into is a little bit later. It's not 623 00:34:48,920 --> 00:34:52,600 Speaker 1: just dogs, um so, it's it's mammals in general. So, 624 00:34:52,760 --> 00:34:56,359 Speaker 1: but the dogs, the dogs alongside humans, they're they're they're 625 00:34:56,400 --> 00:34:59,239 Speaker 1: in close proximity to humans. And you could probably make 626 00:34:59,280 --> 00:35:06,360 Speaker 1: an argument the dog population is an essentially invasive, unbalanced population, 627 00:35:06,480 --> 00:35:10,160 Speaker 1: much like the humans. Oh yeah, certainly. Yeah. Um so 628 00:35:10,200 --> 00:35:14,480 Speaker 1: instead of eradicating them. What are they doing? Well, the 629 00:35:14,520 --> 00:35:19,880 Speaker 1: Carter Foundation is supplying people with callers chains and twenty 630 00:35:20,480 --> 00:35:24,200 Speaker 1: twenty incentive payments to tie their dogs up away from 631 00:35:24,239 --> 00:35:27,279 Speaker 1: the water supply for a two week period and that's 632 00:35:27,600 --> 00:35:30,879 Speaker 1: enough time for the female worms to emerge and die 633 00:35:30,960 --> 00:35:33,440 Speaker 1: on dry land. Yeah, and I would imagine twenty dollars 634 00:35:33,600 --> 00:35:37,560 Speaker 1: is a long way in these communities. Um. And the 635 00:35:37,600 --> 00:35:39,640 Speaker 1: idea here is if they're chained up, they're not going 636 00:35:39,680 --> 00:35:41,920 Speaker 1: to be able to contaminate the water sources and then 637 00:35:41,920 --> 00:35:44,879 Speaker 1: spread the parasite all over again. So yeah, So there 638 00:35:45,040 --> 00:35:48,920 Speaker 1: is research that shows that it is in other mammals, 639 00:35:48,920 --> 00:35:50,400 Speaker 1: and I'm going to talk about that in a second. 640 00:35:50,600 --> 00:35:53,879 Speaker 1: But the dogs themselves, because they're living, like we said, 641 00:35:53,920 --> 00:35:58,240 Speaker 1: adjacent to these communities, they're more likely to infect humans 642 00:35:58,400 --> 00:36:00,680 Speaker 1: and start this process all over again them. Now, one 643 00:36:00,680 --> 00:36:03,840 Speaker 1: thing we haven't really mentioned is how the dogs specifically 644 00:36:03,880 --> 00:36:08,960 Speaker 1: are picking up the infection. Yeah, and this is entirely Yeah. 645 00:36:09,000 --> 00:36:12,239 Speaker 1: I mean, we could assume that it might be from 646 00:36:12,239 --> 00:36:15,360 Speaker 1: a water source. However, there there have been two guesses 647 00:36:15,440 --> 00:36:17,799 Speaker 1: and this leads directly into the paper I'm about to 648 00:36:17,840 --> 00:36:23,839 Speaker 1: talk about eating tadpoles or eating fish cuts um from 649 00:36:24,040 --> 00:36:27,200 Speaker 1: these water sources as well. I think most dog owners 650 00:36:27,200 --> 00:36:29,759 Speaker 1: and people who have been around dogs, they can sympathize 651 00:36:29,800 --> 00:36:32,319 Speaker 1: that the dog is that an extreme disadvantage since most 652 00:36:32,320 --> 00:36:35,720 Speaker 1: dogs will we'll go drink just about any water, uh huh, 653 00:36:35,760 --> 00:36:39,920 Speaker 1: and and it at least knows around in just about anything. 654 00:36:41,040 --> 00:36:43,839 Speaker 1: My dogs. Um, it's been raining here a little bit lately, 655 00:36:43,840 --> 00:36:46,160 Speaker 1: and the mosquitoes have been worse this summer than ever before, 656 00:36:46,600 --> 00:36:49,359 Speaker 1: as we talked about in the Mosquito fatri So, and 657 00:36:49,440 --> 00:36:52,280 Speaker 1: my dogs will go around the yard and drink anytime 658 00:36:52,280 --> 00:36:54,840 Speaker 1: there's like an indent in the dirt and the water, 659 00:36:55,200 --> 00:36:59,040 Speaker 1: uh you know, little pocket forms. My dog will drink that. 660 00:36:59,160 --> 00:37:01,400 Speaker 1: And I'm just thinking like, oh, there's so many mosquito 661 00:37:02,000 --> 00:37:05,040 Speaker 1: larva in that, But you know whatever, it's protein for them. 662 00:37:05,040 --> 00:37:09,920 Speaker 1: I guess it's biomas it is. Yeah, So okay. There 663 00:37:10,000 --> 00:37:13,880 Speaker 1: is a paper published in six uh in the journal 664 00:37:13,920 --> 00:37:17,960 Speaker 1: Emerging Infectious Diseases, and it's called the possible role of 665 00:37:18,000 --> 00:37:23,400 Speaker 1: fish and frogs as para tenetic hosts of dragon Coolest medinensis. 666 00:37:23,640 --> 00:37:27,440 Speaker 1: So that's the Latin term again for anywhere in this study. 667 00:37:27,560 --> 00:37:31,160 Speaker 1: The researchers purposely fed these infected copa pods that we've 668 00:37:31,200 --> 00:37:35,719 Speaker 1: been talked talking about two fish and two tadpoles. Specifically, 669 00:37:35,760 --> 00:37:40,480 Speaker 1: the fish were nile talapia and fat head minnow. Those 670 00:37:40,640 --> 00:37:45,800 Speaker 1: did not develop larva inside of them, but the tadpoles 671 00:37:46,120 --> 00:37:49,520 Speaker 1: did harbor small amounts. So this was connected to the 672 00:37:49,520 --> 00:37:51,920 Speaker 1: whole dog thing. Is well, if they're eating these, maybe 673 00:37:51,920 --> 00:37:55,759 Speaker 1: that's how they're getting them. They said. Uh, So, the 674 00:37:55,800 --> 00:38:00,359 Speaker 1: fact that the fish didn't actually demonstrate larva may not 675 00:38:00,400 --> 00:38:04,000 Speaker 1: be indicative of the fact that the fish are incapable 676 00:38:04,120 --> 00:38:06,520 Speaker 1: of passing them onto a host. It may just be 677 00:38:06,680 --> 00:38:10,759 Speaker 1: that they didn't infect them with enough larva to do so. 678 00:38:10,760 --> 00:38:13,680 Speaker 1: So what was their next step? This is also upsetting 679 00:38:13,719 --> 00:38:17,080 Speaker 1: to me as an animal owner. Uh. They then fed 680 00:38:17,120 --> 00:38:20,719 Speaker 1: the fish and the tadpoles to two ferrets to test out. 681 00:38:21,000 --> 00:38:23,040 Speaker 1: I used to own ferrets. I had four ferrets at 682 00:38:23,040 --> 00:38:27,359 Speaker 1: one time. Uh. One that was fed fish, it did 683 00:38:27,400 --> 00:38:30,279 Speaker 1: not develop larva. However, the one that was fed the 684 00:38:30,320 --> 00:38:34,040 Speaker 1: tadpoles did have larva. And if they did an autopsy 685 00:38:34,080 --> 00:38:37,080 Speaker 1: on this ferret and they found the yeah, so the 686 00:38:37,200 --> 00:38:40,760 Speaker 1: um guinea worm larva passed on and in the ferret 687 00:38:40,800 --> 00:38:42,800 Speaker 1: it probably would have grown into a worm and burst 688 00:38:42,840 --> 00:38:45,360 Speaker 1: out as it as it does in humans and now dogs, 689 00:38:45,760 --> 00:38:49,600 Speaker 1: so we know the species can survive in tadpoles as 690 00:38:49,640 --> 00:38:53,920 Speaker 1: hosts as well. Now, the study confirms their suspicions that 691 00:38:54,120 --> 00:38:57,440 Speaker 1: mammals in the area in general have been getting affected 692 00:38:57,440 --> 00:39:01,560 Speaker 1: with a worm. So we're talking about domestic fair it's cats, dogs, 693 00:39:01,800 --> 00:39:05,040 Speaker 1: as well as monkeys in the area to um they 694 00:39:05,040 --> 00:39:07,680 Speaker 1: can all serve as hosts for the worm. Now, as 695 00:39:07,680 --> 00:39:13,080 Speaker 1: we mentioned earlier, the dogs themselves are are more adjacent 696 00:39:13,120 --> 00:39:15,360 Speaker 1: to the communities, so they're more of a concern. But 697 00:39:15,719 --> 00:39:19,439 Speaker 1: according to other research has been done, researchers have known 698 00:39:19,480 --> 00:39:23,640 Speaker 1: for decades that dogs, leopards, and other mammals are in 699 00:39:23,680 --> 00:39:27,719 Speaker 1: the area can acquire similar infections, but they thought it 700 00:39:27,800 --> 00:39:31,319 Speaker 1: was from a different species of dragon coolest, not the 701 00:39:31,360 --> 00:39:35,280 Speaker 1: guinea worm. In the case of the dogs, researchers definitely 702 00:39:35,360 --> 00:39:39,440 Speaker 1: think they're spreading the worms to humans, which presumably hasn't 703 00:39:39,520 --> 00:39:42,200 Speaker 1: been proven yet. With these other mammals we're talking about here, 704 00:39:42,239 --> 00:39:45,319 Speaker 1: I mean, the leopards got a guinea worm by it right, Like, 705 00:39:45,400 --> 00:39:47,240 Speaker 1: we're not going to hang out next to a leopard. 706 00:39:47,680 --> 00:39:51,440 Speaker 1: We're probably not taking drinking the same water. Hopefully right right, 707 00:39:51,440 --> 00:39:54,520 Speaker 1: And I'm thinking the leopard population would also be significantly 708 00:39:54,560 --> 00:40:00,440 Speaker 1: smaller your farm dog population. So this this is all 709 00:40:00,920 --> 00:40:04,280 Speaker 1: rather concerning because it means that all these these efforts, 710 00:40:04,360 --> 00:40:08,359 Speaker 1: this these this decade spanning war against the guinea worm 711 00:40:08,680 --> 00:40:12,359 Speaker 1: is potentially in jeopardy because the worms have been able 712 00:40:12,400 --> 00:40:16,600 Speaker 1: to find refuge in dogs but killing other animals as well, 713 00:40:16,960 --> 00:40:21,520 Speaker 1: and therefore they're always going to have a base camp 714 00:40:21,600 --> 00:40:24,759 Speaker 1: from which to assault the human population. Again. Yeah, and 715 00:40:24,840 --> 00:40:27,200 Speaker 1: the thing that's very concerning about this, as we said, 716 00:40:27,320 --> 00:40:29,359 Speaker 1: they don't know where the dogs are getting these from, 717 00:40:29,480 --> 00:40:34,280 Speaker 1: which means that somewhere out there, probably in a water source, 718 00:40:34,640 --> 00:40:39,720 Speaker 1: there's still lots of guinea worm larvae. So the dogs 719 00:40:39,719 --> 00:40:42,640 Speaker 1: are acquiring it somehow. Where are they acquiring it from, 720 00:40:42,680 --> 00:40:44,960 Speaker 1: How are they acquiring it? Where are these tadpoles that 721 00:40:45,000 --> 00:40:47,600 Speaker 1: they might be eating, you know, or maybe they're passing 722 00:40:47,640 --> 00:40:49,719 Speaker 1: to something other than tadpoles or fish. They just don't 723 00:40:49,760 --> 00:40:52,120 Speaker 1: know yet. There there's still has is a lot of 724 00:40:52,160 --> 00:40:54,320 Speaker 1: research to be done here. You have to be interested 725 00:40:54,360 --> 00:40:56,040 Speaker 1: to see how this plays out, because that does it 726 00:40:56,160 --> 00:40:59,520 Speaker 1: mean that we can still absolutely break the cycle and 727 00:40:59,560 --> 00:41:03,600 Speaker 1: therefore or break the species, or does it mean, we're 728 00:41:03,640 --> 00:41:05,640 Speaker 1: never going to break the species. All we can do 729 00:41:05,920 --> 00:41:09,239 Speaker 1: is just it eliminated from the human population by just 730 00:41:09,920 --> 00:41:15,840 Speaker 1: remaining remaining persistent, like basically the Roman soldiers, and in 731 00:41:15,920 --> 00:41:18,480 Speaker 1: the metaphor here, they're gonna have to just keep fighting 732 00:41:18,520 --> 00:41:21,680 Speaker 1: forever and just not let their guard down. Or if 733 00:41:21,719 --> 00:41:24,520 Speaker 1: we circle back to the Thing as their metaphor, they're 734 00:41:24,560 --> 00:41:26,279 Speaker 1: just going to have to burn everything down to the 735 00:41:26,320 --> 00:41:31,040 Speaker 1: ground until that's just Kurt Russell and Keith David just 736 00:41:31,280 --> 00:41:33,759 Speaker 1: hanging out with a bottle of whiskey, just waiting to 737 00:41:33,800 --> 00:41:35,560 Speaker 1: see which one of them has a guinea worm that's 738 00:41:35,560 --> 00:41:38,000 Speaker 1: going to erupt from them first. This is this is 739 00:41:38,040 --> 00:41:39,560 Speaker 1: good that we've come back around to the to the 740 00:41:39,600 --> 00:41:41,879 Speaker 1: Thing here, because I've been thinking about a lot. I've 741 00:41:41,880 --> 00:41:44,560 Speaker 1: been writing a little bit about the Thing for the 742 00:41:44,680 --> 00:41:49,400 Speaker 1: upcoming Monster Science episodes, and I've been I've been thinking 743 00:41:49,400 --> 00:41:51,799 Speaker 1: about that whole scenario of like what happens when the 744 00:41:51,840 --> 00:41:55,920 Speaker 1: Thing reaches the rest of the population. It's it's proposed 745 00:41:56,239 --> 00:41:58,200 Speaker 1: in the movie if I remember correctly, and I believe 746 00:41:58,239 --> 00:42:00,480 Speaker 1: there's a comic series that did this as well, where 747 00:42:00,480 --> 00:42:05,319 Speaker 1: basically it's like out of control biomass explosion of things 748 00:42:05,480 --> 00:42:08,120 Speaker 1: if it gets to a major populationship. Right, the way 749 00:42:08,160 --> 00:42:10,279 Speaker 1: they showed in the movie is Wilfred Brimley has that 750 00:42:10,320 --> 00:42:13,759 Speaker 1: little like Commodore sixty four like projection, and it's like 751 00:42:14,040 --> 00:42:16,880 Speaker 1: it's like do do do? It shows like one vector 752 00:42:16,920 --> 00:42:19,680 Speaker 1: like touched as another vector, and then it's just like boom, 753 00:42:19,680 --> 00:42:22,920 Speaker 1: It just like spreads super fast. Yeah. It's like the 754 00:42:23,080 --> 00:42:24,880 Speaker 1: only reason why they were able to keep it at 755 00:42:24,880 --> 00:42:28,760 Speaker 1: bay is because they're in an isolated area. I guess 756 00:42:28,800 --> 00:42:31,080 Speaker 1: the same could be said here, right, is that like 757 00:42:31,160 --> 00:42:36,080 Speaker 1: because these are such impoverished nations that aren't really uh 758 00:42:36,440 --> 00:42:39,720 Speaker 1: connecting or networking in the same way as first world 759 00:42:39,800 --> 00:42:43,719 Speaker 1: nations are. Uh, that's keeping the warrant from spreading even 760 00:42:43,719 --> 00:42:48,439 Speaker 1: further as well. Although we also, I mean, if let's say, 761 00:42:48,440 --> 00:42:52,120 Speaker 1: like on the off chance, like one of us got infected, uh, 762 00:42:52,360 --> 00:42:54,520 Speaker 1: we would go to a doctor, the doctor would recognize 763 00:42:54,520 --> 00:42:56,759 Speaker 1: what it was, and we would be taking care of 764 00:42:56,800 --> 00:42:59,000 Speaker 1: in like a hospital or something like that. Right, Like, 765 00:42:59,239 --> 00:43:01,920 Speaker 1: we have a healthcare system in place and they would 766 00:43:01,920 --> 00:43:04,160 Speaker 1: know how to deal with it. Plus we have clean 767 00:43:04,239 --> 00:43:08,200 Speaker 1: drinking water. Yeah yeah, and also like your your first 768 00:43:08,600 --> 00:43:11,640 Speaker 1: method of treating the blister just sort of dealing with 769 00:43:11,680 --> 00:43:13,360 Speaker 1: the pain would not be to go down to the 770 00:43:13,360 --> 00:43:16,960 Speaker 1: local stream. You're probably going to back up. Yeah. Um. Now, 771 00:43:16,960 --> 00:43:20,200 Speaker 1: as far as the thing goes, I think when when 772 00:43:20,200 --> 00:43:23,320 Speaker 1: I try and think about it reaching the major population centers, 773 00:43:23,840 --> 00:43:27,560 Speaker 1: I think that either a, it's only going to do 774 00:43:27,640 --> 00:43:29,880 Speaker 1: what it has to do to get hold of a 775 00:43:29,920 --> 00:43:34,359 Speaker 1: spaceship and leave the plants. Who Yeah, so that's one possibility. 776 00:43:34,520 --> 00:43:37,279 Speaker 1: The second possibility is that it just goes crazy and 777 00:43:37,360 --> 00:43:41,960 Speaker 1: just takes over the biomass of everything, or it reaches 778 00:43:42,200 --> 00:43:47,960 Speaker 1: parasitic equilibrium, like like other creatures in our world that infiltrates, 779 00:43:47,960 --> 00:43:51,440 Speaker 1: say an aunt colony or some other kind of community 780 00:43:51,520 --> 00:43:53,480 Speaker 1: or system. Yeah, you can only go so far with it. 781 00:43:53,800 --> 00:43:56,799 Speaker 1: You don't want to kill the host. We talked about 782 00:43:56,800 --> 00:43:59,360 Speaker 1: this in the episode that we did on the physics 783 00:43:59,360 --> 00:44:03,279 Speaker 1: and science behind vampires drinking blood, that there's only so 784 00:44:03,280 --> 00:44:06,960 Speaker 1: far that vampires could go before they basically eradicated themselves. Right. So, 785 00:44:07,080 --> 00:44:09,000 Speaker 1: and you see that in successful parasites. You can't be 786 00:44:09,040 --> 00:44:13,279 Speaker 1: a successful parasite if you just wipe out the ship 787 00:44:13,400 --> 00:44:16,520 Speaker 1: that you need for your journey. Yeah, that's a good point. 788 00:44:16,719 --> 00:44:19,400 Speaker 1: And then back to the management thing, I wonder if 789 00:44:19,400 --> 00:44:23,400 Speaker 1: there's a fourth scenario in which the thing infects the 790 00:44:23,520 --> 00:44:26,640 Speaker 1: population at large and we realize, hey, we just got 791 00:44:26,640 --> 00:44:28,759 Speaker 1: to manage the heck out of this, so we're gonna 792 00:44:28,760 --> 00:44:33,000 Speaker 1: implement buddy systems. You can never be alone or or 793 00:44:33,040 --> 00:44:34,960 Speaker 1: maybe it's like a only you have to be three 794 00:44:35,000 --> 00:44:38,440 Speaker 1: people together the same point, because there's that scene in 795 00:44:38,520 --> 00:44:42,640 Speaker 1: the in the prequel remake where like, doesn't it infect 796 00:44:42,680 --> 00:44:45,040 Speaker 1: two people at the same time by just like smushing 797 00:44:45,120 --> 00:44:47,360 Speaker 1: up against one person and then that was like the 798 00:44:47,400 --> 00:44:50,080 Speaker 1: big special effect from that movie where like two people 799 00:44:50,120 --> 00:44:52,360 Speaker 1: were merged together and kind of crawling around like a 800 00:44:52,400 --> 00:44:55,080 Speaker 1: scorpion on the floor. Yeah, they had to reverse engineer 801 00:44:55,200 --> 00:44:59,279 Speaker 1: the that weird corpse that they um. Well, maybe it 802 00:44:59,320 --> 00:45:02,240 Speaker 1: just means that that every day, like twice a day, 803 00:45:02,280 --> 00:45:04,960 Speaker 1: everybody at your work or in your home has to 804 00:45:04,960 --> 00:45:07,040 Speaker 1: do that blood do the blood test where you burn 805 00:45:07,080 --> 00:45:11,600 Speaker 1: their blood. Yeah, if only finding guinea worm larvae was 806 00:45:11,640 --> 00:45:14,040 Speaker 1: as easy as just burning your blood and making it 807 00:45:14,120 --> 00:45:18,839 Speaker 1: a jump up and attack you. All Right, Well, there 808 00:45:18,880 --> 00:45:22,839 Speaker 1: you have it. If you have thoughts about guinea worm 809 00:45:23,000 --> 00:45:26,160 Speaker 1: or the thing, right into us. We're get in touch 810 00:45:26,200 --> 00:45:28,600 Speaker 1: with us. We're always happy to talk about that, and hey, 811 00:45:28,600 --> 00:45:31,120 Speaker 1: If you want to learn more about the Carter Center's 812 00:45:31,200 --> 00:45:34,799 Speaker 1: efforts Carter Foundations efforts against guinea worm, head on over 813 00:45:34,840 --> 00:45:38,080 Speaker 1: to uh Carter Center dot org. UH they have a 814 00:45:38,080 --> 00:45:41,399 Speaker 1: pretty pretty awesome website. It's pretty easy to find well worth. 815 00:45:41,440 --> 00:45:44,839 Speaker 1: Any of their programs are ongoing. Yeah, and one other 816 00:45:45,000 --> 00:45:47,000 Speaker 1: quick plug I want to mention here on the show, 817 00:45:47,400 --> 00:45:50,000 Speaker 1: we are about to do one of our first live 818 00:45:50,040 --> 00:45:53,719 Speaker 1: events with Joe, Robert and myself. It's gonna be at 819 00:45:53,760 --> 00:45:57,680 Speaker 1: the upcoming convention in early September in New York City. 820 00:45:57,760 --> 00:45:59,480 Speaker 1: So if you're in the area and you're a Star 821 00:45:59,520 --> 00:46:01,920 Speaker 1: Trek and we are going to be at Star Trek 822 00:46:01,960 --> 00:46:05,799 Speaker 1: Mission New York, and we're gonna be talking about planetary 823 00:46:05,840 --> 00:46:09,080 Speaker 1: contamination while we're there. So if you want to meet us, 824 00:46:09,120 --> 00:46:12,279 Speaker 1: you want to come see the show live, or maybe 825 00:46:12,320 --> 00:46:15,239 Speaker 1: you've got friends who are just into planetary contamination and 826 00:46:15,239 --> 00:46:17,239 Speaker 1: are also Star Trek fans that are gonna be there. 827 00:46:17,640 --> 00:46:20,480 Speaker 1: Let them know that's where we're gonna be and we're 828 00:46:20,520 --> 00:46:22,680 Speaker 1: looking forward to It's gonna be a blast. Yeah, and 829 00:46:22,719 --> 00:46:27,120 Speaker 1: we may institute fiery blood tests, yeah, I think everybody. 830 00:46:27,120 --> 00:46:29,080 Speaker 1: I think that's how we'll kick it offs. Have everybody 831 00:46:29,120 --> 00:46:31,200 Speaker 1: do a blood test if they you have to use 832 00:46:31,239 --> 00:46:33,080 Speaker 1: like a hot wire, though you can't just use like 833 00:46:33,080 --> 00:46:36,440 Speaker 1: a lighter or something like that. Uh. The other way 834 00:46:36,480 --> 00:46:38,880 Speaker 1: to get in touch with this, of course, after you've 835 00:46:38,920 --> 00:46:40,880 Speaker 1: gone to the website, after you've gone to the social 836 00:46:40,880 --> 00:46:43,520 Speaker 1: media is you can always write us the old fashioned 837 00:46:43,560 --> 00:46:56,000 Speaker 1: way at blow the mind at how stuff works dot com. 838 00:46:56,040 --> 00:46:58,520 Speaker 1: Well more on this than pathands of other topics. Because 839 00:46:58,640 --> 00:47:15,319 Speaker 1: how stuff Works dot Com I think the Big Four 840 00:47:15,440 --> 00:47:19,600 Speaker 1: start proper part far f