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Speaker 1: What it's that time, time, time, time, luck and loak.

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Speaker 1: So Michael Verie Show is on the air. Chris Colosso

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Speaker 1: is our guest. He is my new, relatively new allergist.

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Speaker 1: He's been my wife Salar just for five years.

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Speaker 2: She's had amazing results and I wanted him to come

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Speaker 2: on with it being when we started. He said, look,

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Speaker 2: we're about to start pollen season, so you are going

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Speaker 2: to have a flare. Let's talk about what we're going

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Speaker 2: to do. And I said, that's a perfect time to

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Speaker 2: have you on the show. I like the fact that

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Speaker 2: he very patiently answers all my many questions and you

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Speaker 2: can imagine what it's like to be my doctor. Mary

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Speaker 2: Telly Bowden told me one time that I shouldn't ask

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Speaker 2: so many questions. It's distracting, and I just laughed and

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Speaker 2: I said, Mary, tell you don't know.

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Speaker 3: That's that's just me.

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Speaker 2: Every doctor this s Treamy will tell you that, and

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Speaker 2: they all know, they all hate it, but they all know. Anyway,

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Speaker 2: he patiently answered my questions and with a lifetime of sneezing,

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Speaker 2: runny eyes congestion. I wanted him to share with you

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Speaker 2: his experience because he kind of geeks out on this stuff,

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Speaker 2: and I'm glad to know that somebody does.

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Speaker 3: Chris Colosso is our guest.

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Speaker 2: So doctor Colosso, we see this pollen that's coming down,

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Speaker 2: and you were talking about you and I were talking

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Speaker 2: about this being the season where it really causes people

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Speaker 2: to flare. What are the big allergies and antigens that

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Speaker 2: people would know the street name of that make this

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Speaker 2: season so bad?

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Speaker 4: So you know this this season, everybody, you know, all

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Speaker 4: that yellow stuff you see coding the oak pollen is

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Speaker 4: going to you know, is going to go through the roof,

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Speaker 4: I mean every street and you don't. And people are like, oh,

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Speaker 4: should I take down my oak tree in my arm

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Speaker 4: And I'm like, no, it's going to make no difference

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Speaker 4: because the pollen level is going.

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Speaker 5: To be thick in the air.

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Speaker 4: And you can and you can you know, on our

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Speaker 4: website we have you know, there's a link to the

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Speaker 4: City of Houston pollen counter, and you know it'll get

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Speaker 4: up to the thousands and thousands of pollen count in

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Speaker 4: the air.

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Speaker 5: And the biggest you know trees over here that we have.

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Speaker 4: Trouble with is old pecan ash and you know, and

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Speaker 4: they start off at you know, different times, and so

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Speaker 4: as reason to be a little bit early, oak is

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Speaker 4: through the major springtime and then you know, pick contends

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Speaker 4: to be a.

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Speaker 5: Little bit later in the season.

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Speaker 4: But besides that, you know, the hedges and all those

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Speaker 4: things that are pollinating. Springtime tends to be the worst

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Speaker 4: for more for most patients. And we have patients who

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Speaker 4: are you know, typically they'll have allergy to uh to

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Speaker 4: springtime trees that they all show a dust my allergy

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Speaker 4: and so, you know, and that's why sometimes when I

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Speaker 4: explain to patients, I was like, they're like, but dust say,

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Speaker 4: I don't feel anything with the dust smiles, And it's like, no,

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Speaker 4: you probably do. But it's just that you have this

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Speaker 4: baseline because the dust my stuff is there year around, right,

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Speaker 4: so you have symptoms throughout the year, and so you

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Speaker 4: just sort of if you will, you're sort of used

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Speaker 4: to being miserable, and then you have this and then

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Speaker 4: a long come spring and just adds on to that.

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Speaker 4: And so part of controlling allergy is trying to reset

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Speaker 4: that baseline. And so as I did with Michael, I

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Speaker 4: stressed with him that you you know, make sure that

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Speaker 4: you do dust my covers. Now dust my covers are

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Speaker 4: not going to you know, one hundred percent eliminate dust mites,

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Speaker 4: but it's going to drop the load. So it's going

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Speaker 4: to drop that load. And so now that baseline is

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Speaker 4: set a little bit lower so that when that spring

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Speaker 4: pollen comes hits you, you're not already at the super

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Speaker 4: high level of you know, being miserable. And so that's

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Speaker 4: why you know, seeing a specialist you know, can help

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Speaker 4: you understand and sort of target the allergy from you know,

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Speaker 4: not only just medicines, but also avoidance.

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Speaker 5: Measures and other treatment and.

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Speaker 4: Modalities, and that's that will just help you feel better overall.

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Speaker 3: Chris colossos ourselves.

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Speaker 2: He is an allergist and his clinic is Advanced Allergy

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Speaker 2: and Asthma Center.

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Speaker 5: Go ahead. That was just.

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Speaker 4: Oh, Michael, I just want to you know, we are

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Speaker 4: Advanced Asthma Analogy Center, but it's you know, it's semantic

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Speaker 4: allergies before let me ask you this advance asthma analergy.

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Speaker 3: Okay, let me ask you this.

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Speaker 2: So this treatment to make your body not you know

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Speaker 2: through these like one of the forms of treatment.

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Speaker 3: Is the shots.

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Speaker 2: And that's what I've started doing, is what's my wife

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Speaker 2: has gottencouraged with if our body no longer reacts to

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Speaker 2: the pollen, when when is there any downside to that?

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Speaker 2: I mean, did our body react to try to protect us?

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Speaker 5: No, they just remember that arm of the immune system.

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Speaker 4: Your body started reacting to the pollen, not because it

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Speaker 4: was truly protecting you. That arm of the immune system

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Speaker 4: was designed to fight parasites. But when you don't have

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Speaker 4: much parasite exposure, you don't have you know, worms and

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Speaker 4: those kinds of things, it had nothing to do and

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Speaker 4: so it was not it wasn't reacting in the first

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Speaker 4: place to protect you. It sort of it started reacting

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Speaker 4: just because it wasn't busy enough to do that, and

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Speaker 4: so that comes. You know, there's an interesting thing known

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Speaker 4: as the.

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Speaker 5: Hygiene hypothesis of why allergies go.

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Speaker 4: And it's very interesting with something you said, So your wife,

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Speaker 4: like me, grew up in India, and it's very interesting.

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Speaker 4: Allergy tends to be a disease of the advanced world.

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Speaker 5: In in the.

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Speaker 4: In the Third World, they tend to have much less allergy.

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Speaker 4: And the thinking is a lot of that has to

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Speaker 4: do because we get exposed.

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Speaker 5: You know, people who grew up in the Third World or.

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Speaker 4: Even in farming communities tend to be exposed to a

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Speaker 4: higher level of endotoxin.

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Speaker 5: And endotoxin is just.

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Speaker 4: Dirt or you know, for lack of a better word,

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Speaker 4: and sometimes what you find in manure and that kind

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Speaker 4: of stuff outside, and when that part of the immune

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Speaker 4: system is stimulated, it tends to suppress the allergic response.

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Speaker 4: And so remember how you said that, you know, when

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Speaker 4: your wife first came, she had never had trouble with allergy, right,

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Speaker 4: And that's what we see over here too, Like I

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Speaker 4: never had allergy for twenty years, And it's only being in,

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Speaker 4: you know, in sort of a cleaner environment that that

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Speaker 4: arm of the immune system starts reacting, whereas in you know,

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Speaker 4: in a dirty environment, if you will, or just being

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Speaker 4: exposed to more dirt, it keeps the allergy part of

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Speaker 4: it under control.

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Speaker 2: So it's almost if you don't use it, you lose

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Speaker 2: it or a weak muscle. Because the developed world, and

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Speaker 2: especially the United States, is so hygienic, our body does

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Speaker 2: not develop the ability to fight off these things, and

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Speaker 2: so when they hit us, it hits us harder as

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Speaker 2: opposed to growing up on the rough streets of the

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Speaker 2: third world sort of thing, and your body has has

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Speaker 2: developed an immunity to that, it's a fascinating hypothesis.

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Speaker 3: I'm absolutely fascinating.

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Speaker 4: Right, And that's what's considered the hygiene hypothesis. And so

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Speaker 4: it's it's not so much that the body didn't develop

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Speaker 4: the immunity, but it's that the infection keeps this arm

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Speaker 4: of the immune system, the allergy part, not reacting. And

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Speaker 4: once you take away you know a lot of those

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Speaker 4: the infecttion.

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Speaker 5: I know you know.

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Speaker 4: And they talk about just being outside and playing in

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Speaker 4: the dirt and those companies helped decrease allergies.

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Speaker 2: Let's talk about that, because you and I have had

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Speaker 2: that conversation. I think it's important. Doctor Chris Colosso advanced

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Speaker 2: asthma an allergy coming.

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Speaker 4: Up today to the Colonial house requirements and receiver free

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Speaker 4: even we're recorded.

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Speaker 2: Doctor Chris Colosso has been my wife's allargist for five years.

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Speaker 3: She's had phenomenal results.

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Speaker 2: I have recently started with him and he answered all

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Speaker 2: my questions and he literally sat down. He owns the clinic,

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Speaker 2: so it's not like being part of one of the

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Speaker 2: big hospital systems where you got to turn people so fast.

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Speaker 2: But he in much the same way that I have

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Speaker 2: conversations with Mohit Kara and Jim Munks and other doctors

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Speaker 2: that are just you know, they geek out over their

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Speaker 2: area of expertise and I love that and I asked

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Speaker 2: him to share some of that with you, doctor Colosso

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Speaker 2: let's talk about what people if someone doesn't have Medicare,

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Speaker 2: doesn't have a healthcare program, doesn't is not able to

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Speaker 2: come and see you, what are some basic things that

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Speaker 2: people can do to.

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Speaker 3: Get through pollen season when they're having difficulty.

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Speaker 4: So you know, the best thing to do is to

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Speaker 4: try and avoid it. So it's so sinus instance. Now

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Speaker 4: that's something simple and.

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Speaker 5: You know, very easy to do. And so if you do,

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Speaker 5: go take the dog out for a walk. As soon

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Speaker 5: as you come back, do a science trends.

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Speaker 4: That's you know, if you're going to blow all your

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Speaker 4: leaves out, wear a mask because the higher level of

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Speaker 4: pollen that you that you expose yourself to, the more

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Speaker 4: chance that you're going to have were symptoms. The other

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Speaker 4: the one of the other things you can do is

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Speaker 4: you know, if you know that you know dust may

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Speaker 4: be a trigger or those kind of things, then you know,

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Speaker 4: keep the humidity low because the lower the humidity in

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Speaker 4: the house, the less dust, my populations, uh, you know,

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Speaker 4: survive or you know, your decreased.

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Speaker 5: That's my population.

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Speaker 4: And then you know there's medicines and so you know,

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Speaker 4: using the medicines during you know, during pollen season and

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Speaker 4: now since that most of these things are over the counter,

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Speaker 4: So using an antihistamine and using a nose pray will

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Speaker 4: help control the symptoms so you're.

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Speaker 5: Not as miserable.

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Speaker 4: So in those you know, and that's in that way

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Speaker 4: you can try and you know, sort of keep the

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Speaker 4: symptoms controlled. That this would not be the time to

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Speaker 4: you know, when you know, when you see you know,

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Speaker 4: these guys blowing all the pollen all around. To walk

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Speaker 4: through that pollen cloud, you're going to be miserable, and

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Speaker 4: so you know, trying to sort of avoid it. Using

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Speaker 4: and using the medications that are over the counter judiciously

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Speaker 4: will help you a lot.

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Speaker 2: You seem to prefer to start with zyrtech and if

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Speaker 2: somebody can handle it, use that and if they can't,

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Speaker 2: move on, why is that is that the best over

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Speaker 2: the counter drug?

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Speaker 4: I feel Zertec tends to work a little bit better

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Speaker 4: than some of the antihistamines, but you know, it as

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Speaker 4: a thing that it can cause drowsiness, and so five

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Speaker 4: percentral maybe a little bit less of the people who

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Speaker 4: take it, you know, will say it makes them sleeping.

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Speaker 4: And so there's other there's other anti histories over the counter.

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Speaker 4: Allegra does not you know, a cross the Bloodbain barrier,

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Speaker 4: and so you know, in pilots or someone with a

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Speaker 4: commercial drug driver's license, you know, i'd say, hey, you

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Speaker 4: need to use Allegra as your anti history because we

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Speaker 4: can't have any of those.

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Speaker 5: You know, you can't have the drowsy and those kinds

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Speaker 5: of things.

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Speaker 2: But you don't start Allegra because you think Zertech, if

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Speaker 2: the person can handle it, is more effective.

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Speaker 5: Typically is a little bit is a little bit better.

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Speaker 4: But you know, everything every and you know, I run

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Speaker 4: into this all the time where patients will tell me, no, doctor,

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Speaker 4: see Allegra.

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Speaker 5: Works better for me or whatever.

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Speaker 4: Everyone's immune system is sort of a little different, and

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Speaker 4: so you know, sometimes patients tend to prefer, you know,

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Speaker 4: which medicine works best for them without the side effects.

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Speaker 4: But I feel Zotech is a is a really good

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Speaker 4: antihistamy to help control.

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Speaker 3: And then after that down the list you would go Allegra,

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Speaker 3: and then what.

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Speaker 5: I go, yeah, mine is clariton.

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Speaker 4: After that, I don't like chronic use of first generation

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Speaker 4: anti hist means because all of those tend to cross

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Speaker 4: the blood brain barrier and they all tend to make

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Speaker 4: you drowsing. And then there was you know, some studies

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Speaker 4: out from a while ago with you know, with New

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Speaker 4: England General Medicine. They talked about you know, long term

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Speaker 4: use of first generation antihistamines maybe and you know, maybe

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Speaker 4: associated with dementia later on. And so I try to

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Speaker 4: avoid using chronic use of first generation anti history means.

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Speaker 3: And the first generation anti histamines are zerotech, Allegra and claritin.

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Speaker 5: No no, no, sorry. The first generation answer his means

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Speaker 5: are bena drow oh okay. And then there's some from

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Speaker 5: Phenomenal in Love. There's a little bit hard to find, okay.

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Speaker 2: So just to wrap that up in case people weren't

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Speaker 2: paying close attention, you're not in favor of using benadryl

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Speaker 2: long term because that was an early drug and you

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Speaker 2: think there may potentially be some problems.

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Speaker 4: With that, right and everyone, you know, And my thing

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Speaker 4: is I explain to patients that the way these anti

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Speaker 4: histamines they tend to block or trap the historine receptor.

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Speaker 4: In the enactive forms of combined histamin benadro will do that.

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Speaker 5: For four to six hours, and then it falls off

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Speaker 5: the receptor, so the receptor is open again, and you

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Speaker 5: have the bad side effect that it can put you

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Speaker 5: to sleep. So why would you do that if there's better,

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Speaker 5: if there's.

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Speaker 4: You know, the most of the second generation anti hist

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Speaker 4: means like zootech and Clarenton Leger and those kind of

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Speaker 4: things last twenty four hours, and they are much less

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Speaker 4: They cause much less drowsiness than the first generations. So

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Speaker 4: that's why I don't like the first generation as instruments.

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Speaker 2: It's very interesting the over the counter of zytech, I think,

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Speaker 2: I mean you talked about it tends to mask problems

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Speaker 2: for people who for those who end up with very

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Speaker 2: chronic conditions. But I would be interested to know, and

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Speaker 2: I don't know if you have any sense what percentage

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Speaker 2: of the population is on one of those latter generation

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Speaker 2: tech Allegro Clerton on a relatively regular basis, which by

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Speaker 2: the way, he put me on zartech and I do

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Speaker 2: fine with it. I wonder what percentage of the population

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Speaker 2: is on that, because I would assume that makes a

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Speaker 2: big difference at least at least to giving people some comfort,

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Speaker 2: some relief.

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Speaker 4: No, I think a lot of people and then they

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Speaker 4: say maybe sixteen hundred million people have allergy. But once

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Speaker 4: those things go over the counter, then you know, I

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Speaker 4: guess at some point they used to be able to

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Speaker 4: crack it, but.

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Speaker 5: Now you don't. But you know, given.

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Speaker 4: How well those you know, the drugs have done. And

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Speaker 4: you know, I see many people who are those antihistamines

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Speaker 4: year around.

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Speaker 5: All the time.

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Speaker 3: Do you see a problem with that?

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Speaker 4: There's pretty good data out and right now, I sometimes

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Speaker 4: you know, like I told you that if zerotech doesn't

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Speaker 4: knock you out, then then it's fine. But you know,

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Speaker 4: I try to make sure that you use drugs that

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Speaker 4: you know don't affect uh, you know, slow you down

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Speaker 4: and those kinds of things.

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Speaker 5: You know.

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Speaker 2: Well, I don't know my wife told you, but Nandata

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Speaker 2: is she said.

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Speaker 3: She says that.

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Speaker 2: It makes her drowsy, which it does, but she didn't

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Speaker 2: tell that it makes her a little angry. And the

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Speaker 2: reason we knew that, the boys and I is because

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Speaker 2: she's never angry. She is the sweetest person one hundred

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Speaker 2: percent of the time. People don't believe she could be

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Speaker 2: that nice. And she started on that, and about the

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Speaker 2: third time she took it, she said, hey, I'm going

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Speaker 2: to take my zyrtech and go to bed. I'm just

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Speaker 2: warning you in case I'm grumpy. I'm not mad at you.

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Speaker 2: It has that effect, but please tell me if I

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Speaker 2: do that. And so she started keeping notes herself and

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Speaker 2: said okay. That's when she came to you and said, okay,

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Speaker 2: I need to switch to something else. Chris Glosso is

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Speaker 2: our guest advanced asthma and allergy. If you would like

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Speaker 2: to go and see him, I would be happy to

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Speaker 2: connect you. Otherwise, we're talking in the middle of pollen season.

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Speaker 2: At least for those of you who don't know. I'm

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Speaker 2: in Houston and in Southeast Texas where we are right

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Speaker 2: about now.

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Speaker 3: Most everybody you talk to is sneezing, nodding, stuffy head eyes.

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Speaker 2: The whole, the whole deal. And that's why I wanted

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Speaker 2: to talk to him today.

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Speaker 5: We'll see a process. Man's the term anal intercourse on

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Speaker 5: your program, Michael Arris.

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Speaker 2: If it's relevant, but his story for journalistic purposes. Chris

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Speaker 2: Klosso is my wife's allergist, has been for five years

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Speaker 2: to great result. She finally dragged me to see him

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Speaker 2: a month or so ago, and I've gone through my

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Speaker 2: tests and I really like the fact that he takes

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Speaker 2: the time to answer all my many questions. I don't

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Speaker 2: believe doctors are gods. I think that doctors are like

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Speaker 2: everyone else, doing the best they can. I love the

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Speaker 2: fact that he quotes studies, which means he's keeping up with, uh,

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Speaker 2: you know, the developments in his field. I think a

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Speaker 2: lot some doctors, not a lot a few doctors, they

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Speaker 2: get kind of they get stuck in the in the

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Speaker 2: ways of doctor Spock's, you know, book on newborns, and

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Speaker 2: they don't keep up with new trends and new developments

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Speaker 2: and new data that's coming out.

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Speaker 3: And he does. And I really like that.

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Speaker 2: Doctor Colosso let's talk about you told me something very interesting.

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Speaker 2: I had had the test done on the allergy test

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Speaker 2: that a lot of people have had earlier in life,

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Speaker 2: where they do the pin pricks and then you see

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Speaker 2: what flares, and y'all have changed the dosage you use

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Speaker 2: for that because people were literally dying through that, and

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Speaker 2: now you have a two pronged approach.

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Speaker 3: Can you explain that?

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Speaker 5: So that's true?

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Speaker 4: So in adults, and so for for allergy testing, my

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Speaker 4: cutoff is sixteen and above. And so in you know,

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Speaker 4: a long time ago, maybe twenty thirty years they would

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Speaker 4: ask the patient, hey, how's your allergy, and you know,

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Speaker 4: usually it's guys, and they'd be like, eh, it's not.

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Speaker 5: That bad dog.

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Speaker 4: And so they would go straight to an intradomal test,

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Speaker 4: where you would inject the allergen into the surface of

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Speaker 4: the skin. And as a result of that, they gave

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Speaker 4: some people anaphleaxis, which is like a full body allergic reaction,

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Speaker 4: almost kill them.

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Speaker 5: And so.

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Speaker 4: Then about you know, maybe twenty five years ago, they said,

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Speaker 4: you can't you know, kill the patient to make the diagnosis.

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Speaker 4: That's not good medicine. And so they change it and

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Speaker 4: they said, you always do a scratch test, so literally

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Speaker 4: we just barely scratch the skin with the extract, and

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Speaker 4: you know, as in your case, Michael, there were several

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Speaker 4: of the things that had strong positive reactions. So you

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Speaker 4: could imagine that if I went, you know, if I

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Speaker 4: didn't do that and I went straight to the needle test,

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Speaker 4: where we'd inject a little bit into the surface of

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Speaker 4: the skin, we could have caused your whole arm to

369
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Speaker 4: swell up and you know, shortness of bread and all

370
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Speaker 4: those things, you know, which is like a full body

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Speaker 4: allergic reaction. And so that's why we now, I don't

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Speaker 4: you know, it's it's kind of hard.

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Speaker 5: But with some of the old hourgies.

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Speaker 4: When I first started, you know, in training, I mean

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Speaker 4: they would do needle tests. That means the introdome test,

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Speaker 4: even on little kids, I don't typically we usually do

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Speaker 4: scratch testing, and whatever's positive is positive. In adults, we

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Speaker 4: do the needle test because it'll pick up some minor

379
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Speaker 4: allergens that you don't see on scratch testing. And so

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Speaker 4: sometimes that way, if the patient you know, decides to

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Speaker 4: do allergen and in a therapy alergy shots, we would

382
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Speaker 4: put not only would reacted on the first step, but

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Speaker 4: also on the second step. And so you know, that's

384
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Speaker 4: that's how we try to do both so as to

385
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Speaker 4: not and do it in a step wise fashion, because

386
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Speaker 4: if someone has a big reaction on scratch testing, I

387
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Speaker 4: would not do the second part that day. Because when

388
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Speaker 4: I first started, you know, a lot of patients would

389
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Speaker 4: be like, now have to see do it. I'll be fine,

390
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Speaker 4: And we go ahead and start three or four and

391
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Speaker 4: then they're like, oh, my throat feels weird, or I

392
00:19:58,359 --> 00:20:01,720
Speaker 4: have difficulties swallowing or you know those kind of things,

393
00:20:01,720 --> 00:20:04,240
Speaker 4: and when we have to stop and you know, treat

394
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Speaker 4: the reaction. And so now we just split it up,

395
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Speaker 4: and someone has a big reaction with just scratch testing,

396
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Speaker 4: we don't do the second part of the allergy testing

397
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Speaker 4: on that day. But then I use usually use both

398
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Speaker 4: of the testing.

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Speaker 5: Data to decide the best way forward.

400
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Speaker 2: So with that data, I know you personally do the

401
00:20:23,280 --> 00:20:27,359
Speaker 2: recipe for the shots. How does that work you personally?

402
00:20:27,440 --> 00:20:28,400
Speaker 2: What do you then do?

403
00:20:30,280 --> 00:20:32,560
Speaker 4: So then I will write a recipe and say, hey,

404
00:20:33,040 --> 00:20:35,920
Speaker 4: so let's just make up something. Let's just say for

405
00:20:35,920 --> 00:20:40,960
Speaker 4: for for the sake of argument, someone and there's case,

406
00:20:41,160 --> 00:20:44,960
Speaker 4: let's say your allergy it's not help Let's see, yeah

407
00:20:45,000 --> 00:20:47,719
Speaker 4: that's true. So let's say you're allergic to dust mites

408
00:20:47,720 --> 00:20:51,960
Speaker 4: and oak and and you know some of the moles

409
00:20:52,040 --> 00:20:55,280
Speaker 4: or whatever, and so then you physically, So I would

410
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Speaker 4: write out a recipe of how much of these different

411
00:21:00,400 --> 00:21:04,040
Speaker 4: extracts that I would put into a vial to make

412
00:21:04,160 --> 00:21:09,119
Speaker 4: up you know, make a vial so that would have

413
00:21:09,200 --> 00:21:10,359
Speaker 4: those extracts in there.

414
00:21:11,160 --> 00:21:12,639
Speaker 5: And then we.

415
00:21:12,520 --> 00:21:17,800
Speaker 4: Would dilute down that vial one hundred thousand fold, and

416
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Speaker 4: then physically.

417
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Speaker 5: You would you know, if we were doing.

418
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Speaker 4: Alergie shots, you would come in. There's two ways, and

419
00:21:23,520 --> 00:21:25,719
Speaker 4: we talked about this. There's different ways you can build up,

420
00:21:26,160 --> 00:21:28,160
Speaker 4: but let's just do the slow normal way.

421
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Speaker 5: Patients would come and.

422
00:21:29,760 --> 00:21:35,560
Speaker 4: They get this most shot first. And each time you

423
00:21:35,640 --> 00:21:39,360
Speaker 4: get a shot, it's a higher dose or a higher concentration,

424
00:21:39,480 --> 00:21:42,560
Speaker 4: and so you're moving up and the goal is to

425
00:21:42,600 --> 00:21:46,480
Speaker 4: get to the highest dose that the patient can tolerate

426
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Speaker 4: without having any systemic symptoms.

427
00:21:50,320 --> 00:21:51,879
Speaker 5: And one of the other things I'll.

428
00:21:51,720 --> 00:21:54,919
Speaker 4: Bring out is, you know why you get shots at

429
00:21:54,920 --> 00:21:58,280
Speaker 4: a doctor's office, but the goal is to try and

430
00:21:58,600 --> 00:22:01,560
Speaker 4: keep you know, so each time, so you start off

431
00:22:01,560 --> 00:22:04,240
Speaker 4: at one is to one hundred thousand delution. Once you

432
00:22:04,320 --> 00:22:07,640
Speaker 4: finish that one hundred thousand dilution will take about four weeks,

433
00:22:07,680 --> 00:22:10,159
Speaker 4: you go to the one is to ten thousand, you

434
00:22:10,240 --> 00:22:12,399
Speaker 4: finish that, you go one is to one thousand, then

435
00:22:12,440 --> 00:22:14,359
Speaker 4: you go one is to one hundred, you one is

436
00:22:14,400 --> 00:22:17,439
Speaker 4: to ten. So each time when you're moving up in shots,

437
00:22:17,440 --> 00:22:20,920
Speaker 4: you're getting a tenfold increase in the concentration of the shot.

438
00:22:22,160 --> 00:22:25,680
Speaker 4: And what that is doing is slowly training the immune

439
00:22:25,720 --> 00:22:29,520
Speaker 4: system to not react to and most of our patients

440
00:22:29,560 --> 00:22:32,040
Speaker 4: tend to, you know, over the period of the shots,

441
00:22:32,560 --> 00:22:36,640
Speaker 4: tend to tolerate the full strength bile, which is you know,

442
00:22:37,200 --> 00:22:40,040
Speaker 4: and you'll see where the vial is yellow because that's

443
00:22:40,119 --> 00:22:43,919
Speaker 4: the color of pollen and so it's fairly thick and

444
00:22:44,119 --> 00:22:45,760
Speaker 4: has a lot of pollm nextract in there.

445
00:22:46,400 --> 00:22:48,960
Speaker 5: But it's only in the higher doses.

446
00:22:48,520 --> 00:22:51,600
Speaker 4: Of the thing that the of the vials that you

447
00:22:51,760 --> 00:22:57,719
Speaker 4: notice that you start seeing, you know, clinical benefit. And

448
00:22:57,720 --> 00:23:00,000
Speaker 4: that's why I warn you that this is too late

449
00:23:00,640 --> 00:23:04,040
Speaker 4: to help you for spring, because spring is sprong or springing,

450
00:23:04,760 --> 00:23:07,760
Speaker 4: and you know, the initial part of the shots is

451
00:23:07,800 --> 00:23:10,800
Speaker 4: not going to help much with that because again, this

452
00:23:10,840 --> 00:23:13,280
Speaker 4: is a process of changing the immune system and it

453
00:23:13,720 --> 00:23:16,119
Speaker 4: you know, took fifty four years for your immune system

454
00:23:16,160 --> 00:23:16,840
Speaker 4: to get this way.

455
00:23:17,440 --> 00:23:19,360
Speaker 5: It would be unreasonable.

456
00:23:18,840 --> 00:23:21,439
Speaker 4: To you know, think that it would change in you know,

457
00:23:21,680 --> 00:23:25,879
Speaker 4: a few weeks. And so you know, alergenemmut therapy is

458
00:23:25,880 --> 00:23:31,240
Speaker 4: a process and and that's why you do it. And

459
00:23:31,600 --> 00:23:34,639
Speaker 4: there's always a risk and so there's a very small

460
00:23:34,720 --> 00:23:37,520
Speaker 4: risk it happens maybe one in five hundred thousand shots,

461
00:23:37,560 --> 00:23:40,560
Speaker 4: but you could because we're giving you stuff you're allergic to,

462
00:23:41,240 --> 00:23:42,960
Speaker 4: and so there's a rare risk that you could have

463
00:23:43,000 --> 00:23:46,000
Speaker 4: an allergic reaction. And that's why you know, with all operations,

464
00:23:46,600 --> 00:23:50,400
Speaker 4: we you know, have them have their own either injectable

465
00:23:50,640 --> 00:23:53,879
Speaker 4: or now nasal at the effort. So that's what the

466
00:23:53,880 --> 00:23:56,600
Speaker 4: guidelines are. And they usually get their shot and they

467
00:23:56,600 --> 00:23:58,520
Speaker 4: have to sit in the clinic for twenty minutes, make.

468
00:23:58,400 --> 00:24:00,159
Speaker 5: Sure everything's good, good go.

469
00:24:01,000 --> 00:24:05,560
Speaker 4: But that's why you know, I don't let patients do

470
00:24:05,720 --> 00:24:09,879
Speaker 4: shots at home because you know, God forbid something would happen.

471
00:24:10,000 --> 00:24:12,119
Speaker 4: You have to be somewhere where someone can take you know,

472
00:24:12,200 --> 00:24:15,240
Speaker 4: help you take care of every reaction.

473
00:24:16,600 --> 00:24:19,720
Speaker 2: Doctor Chris Colosso is our guest. He has been very

474
00:24:19,800 --> 00:24:21,600
Speaker 2: kind to stay with us this long. We will have

475
00:24:21,760 --> 00:24:23,720
Speaker 2: one more segment with him so he can get back

476
00:24:23,720 --> 00:24:27,040
Speaker 2: to his patients. If you want to connect with him,

477
00:24:27,119 --> 00:24:30,880
Speaker 2: it's spelled co l aco. It's Advanced Asthma and Allergy.

478
00:24:31,359 --> 00:24:33,640
Speaker 2: Or you can email me through our website Michael Berryshow

479
00:24:33,680 --> 00:24:35,280
Speaker 2: dot com and I will connect you with him.

480
00:24:36,119 --> 00:24:42,080
Speaker 3: One more segment with doctor Colosso, Community Joy, Alma, Michael Bay,

481
00:24:43,040 --> 00:24:44,639
Speaker 3: Good Show, Paul Plum.

482
00:24:47,080 --> 00:24:51,920
Speaker 2: Doctor Chris Colosso is my wife's allergist and now my allergist,

483
00:24:52,400 --> 00:24:57,879
Speaker 2: and he has UH managed phenomenal healing for her, and

484
00:24:58,040 --> 00:25:00,640
Speaker 2: I asked him at my last appointment if he would

485
00:25:00,640 --> 00:25:03,119
Speaker 2: come on and share with you some of his experiences

486
00:25:03,160 --> 00:25:05,360
Speaker 2: and some of these stories, especially with it now being.

487
00:25:05,240 --> 00:25:09,720
Speaker 3: Full blown UH allergy season. Uh Doc, I want to go.

488
00:25:09,760 --> 00:25:11,520
Speaker 2: I want to move kind of fast here because I'm

489
00:25:11,560 --> 00:25:15,879
Speaker 2: going through my report and a legal disclaimer. I have

490
00:25:16,000 --> 00:25:18,480
Speaker 2: told doctor colosso he can talk about my case because

491
00:25:18,480 --> 00:25:21,520
Speaker 2: they don't like to do that. The first thing that

492
00:25:21,640 --> 00:25:25,040
Speaker 2: you test for on indoor allergens is dust mighte.

493
00:25:25,080 --> 00:25:25,520
Speaker 5: Why is that.

494
00:25:27,200 --> 00:25:30,320
Speaker 4: Because in Houston, dust might is a you know, a

495
00:25:30,520 --> 00:25:34,840
Speaker 4: very common allergen that people get sensitized to. And dust

496
00:25:34,920 --> 00:25:37,600
Speaker 4: mites are around anywhere in the country where it's very humid.

497
00:25:37,640 --> 00:25:40,359
Speaker 4: They're actually even and you know you can have it

498
00:25:40,400 --> 00:25:43,440
Speaker 4: in New Mexico, but they tend to the population tends

499
00:25:43,480 --> 00:25:46,240
Speaker 4: to be very high in places where it's very humid,

500
00:25:46,920 --> 00:25:49,080
Speaker 4: and you know, you think about it, dust mites is

501
00:25:49,080 --> 00:25:51,119
Speaker 4: an indoor allergy and and so all night you sleep,

502
00:25:51,160 --> 00:25:54,159
Speaker 4: you bleed it in and that's why you have a

503
00:25:54,680 --> 00:25:57,920
Speaker 4: good chance of becoming allergic to it. And because that

504
00:25:58,040 --> 00:26:01,239
Speaker 4: exposure is there chronically, and so that's why it's one

505
00:26:01,280 --> 00:26:05,440
Speaker 4: of the major indoor allergens all over the country that

506
00:26:05,560 --> 00:26:09,480
Speaker 4: would drive allergies, and so that's why most allergists will

507
00:26:09,560 --> 00:26:10,240
Speaker 4: check for dust.

508
00:26:10,359 --> 00:26:13,040
Speaker 2: Might The next thing on the list was dog hair.

509
00:26:13,160 --> 00:26:15,480
Speaker 2: Fortunately I'm not allergic to that, but I am allergic

510
00:26:15,560 --> 00:26:17,840
Speaker 2: to cat hair, which was the one after that. How

511
00:26:18,280 --> 00:26:21,320
Speaker 2: often is that flaring for people are coming up as positive?

512
00:26:22,680 --> 00:26:25,760
Speaker 4: A cat is a very common allergen, and most people

513
00:26:25,840 --> 00:26:28,840
Speaker 4: will will know this. Cat and cat allogen tends to

514
00:26:28,920 --> 00:26:32,600
Speaker 4: be a little bit worse for patients than dog allergen.

515
00:26:32,640 --> 00:26:36,320
Speaker 4: And partly that's because cat allergen is very very sticky,

516
00:26:37,040 --> 00:26:39,840
Speaker 4: and so it tends to sort of spread all over

517
00:26:39,920 --> 00:26:43,320
Speaker 4: the house very quickly, and so patients can even if

518
00:26:43,400 --> 00:26:46,040
Speaker 4: you you know, someone who's very allergic to cat, if

519
00:26:46,080 --> 00:26:49,639
Speaker 4: you sit in the side in a car and someone

520
00:26:49,720 --> 00:26:52,360
Speaker 4: who had a cat and you have a cat allergy,

521
00:26:53,040 --> 00:26:56,360
Speaker 4: you will notice that evening that you have more symptoms well,

522
00:26:56,720 --> 00:26:59,200
Speaker 4: and so so that's a thing, and that's that's a

523
00:26:59,240 --> 00:26:59,600
Speaker 4: real thing.

524
00:27:00,240 --> 00:27:04,040
Speaker 3: Was roach mix and mixed feathers? Why are those so high?

525
00:27:05,280 --> 00:27:08,680
Speaker 4: So roach makes we you know, tend to do again

526
00:27:08,760 --> 00:27:11,159
Speaker 4: because you know, roaches, if you know some people, if

527
00:27:11,160 --> 00:27:13,720
Speaker 4: you exposed to it an apartment, I mean most of

528
00:27:14,040 --> 00:27:16,040
Speaker 4: you know our patient, My patients pray for roaches, so

529
00:27:16,119 --> 00:27:18,640
Speaker 4: that's not a problem. But if it is positive, then

530
00:27:19,080 --> 00:27:22,000
Speaker 4: it's it's an It's an allergen that can drive sort

531
00:27:22,040 --> 00:27:25,600
Speaker 4: of allergy and asthma a lot. And so you know,

532
00:27:25,640 --> 00:27:27,919
Speaker 4: if it is positive, I tell patients to do stuff

533
00:27:27,960 --> 00:27:32,080
Speaker 4: to you know, mitigate roaches. Feather sometimes not a very

534
00:27:32,119 --> 00:27:35,600
Speaker 4: strong allergen, but if you have a lot of down

535
00:27:35,680 --> 00:27:38,960
Speaker 4: comforters and pillows and those kinds of things, and you're

536
00:27:38,960 --> 00:27:41,359
Speaker 4: getting worse at night when you sleep.

537
00:27:41,160 --> 00:27:43,240
Speaker 5: And may not be the best thing for you to do.

538
00:27:43,960 --> 00:27:46,359
Speaker 2: So in your listing, if those were the indoor allergens

539
00:27:46,440 --> 00:27:48,119
Speaker 2: you test for, and you said to me that what

540
00:27:48,280 --> 00:27:50,080
Speaker 2: you test for is about ninety five percent of what

541
00:27:50,160 --> 00:27:51,560
Speaker 2: people are going to have. You could test for a

542
00:27:51,640 --> 00:27:53,760
Speaker 2: million things, but this is what it makes the most sense.

543
00:27:54,119 --> 00:27:57,439
Speaker 2: In your listing of trees, live oak followed back pecan

544
00:27:57,560 --> 00:28:00,399
Speaker 2: than white ash, did you list these in order of

545
00:28:00,600 --> 00:28:04,280
Speaker 2: how likely someone typically is to get them or how

546
00:28:04,880 --> 00:28:07,160
Speaker 2: how prevalent these trees are, Although I guess that would

547
00:28:07,240 --> 00:28:08,720
Speaker 2: those would be the same thing maybe.

548
00:28:09,200 --> 00:28:12,680
Speaker 4: I think it's more those are the most common ones

549
00:28:12,720 --> 00:28:15,000
Speaker 4: in Houston, and I didn't. I didn't at the time.

550
00:28:15,080 --> 00:28:17,960
Speaker 4: I didn't think about, you know, just based on prevalence.

551
00:28:18,000 --> 00:28:20,720
Speaker 4: But I just listed the most common trees when I

552
00:28:20,800 --> 00:28:22,800
Speaker 4: first set out, you know, the practice. You know, I've

553
00:28:22,840 --> 00:28:26,280
Speaker 4: got with a botanist from Greer, who's you know, one

554
00:28:26,320 --> 00:28:29,719
Speaker 4: of the major companies that supply alogy extracts, and so they,

555
00:28:29,920 --> 00:28:32,200
Speaker 4: you know, tell you which are the most prevalent trees

556
00:28:32,240 --> 00:28:34,480
Speaker 4: in the area and those kind of things on what

557
00:28:34,640 --> 00:28:37,840
Speaker 4: you should be testing for. And but you know, oh,

558
00:28:37,960 --> 00:28:39,600
Speaker 4: cash and pakan are the ones that are you know,

559
00:28:39,800 --> 00:28:41,720
Speaker 4: very common, and so that's what ones we pay.

560
00:28:41,960 --> 00:28:44,320
Speaker 2: Interestingly, I don't even like pine, and that was one

561
00:28:44,320 --> 00:28:46,720
Speaker 2: of the only trees I was not allergic to. You

562
00:28:46,840 --> 00:28:51,160
Speaker 2: then went from there to grasses, Bermuda, Johnson vernal mix

563
00:28:51,800 --> 00:28:53,040
Speaker 2: and bahia.

564
00:28:55,440 --> 00:28:58,400
Speaker 3: Saint Augustine within that, Am I am I mixing that up?

565
00:28:58,480 --> 00:28:58,840
Speaker 4: Or is that not?

566
00:28:59,040 --> 00:28:59,840
Speaker 5: So? No, there's no.

567
00:29:00,240 --> 00:29:02,720
Speaker 4: So Saint Augustine is a you know as a broad

568
00:29:02,840 --> 00:29:05,920
Speaker 4: leaf grass, and Saint Augustine would have to grow a

569
00:29:06,040 --> 00:29:07,760
Speaker 4: foot before it pollinatees.

570
00:29:07,920 --> 00:29:11,120
Speaker 5: Okay, so most most you know won't. No one ever

571
00:29:11,240 --> 00:29:13,880
Speaker 5: lets it grow that long, and so that's why we don't.

572
00:29:13,920 --> 00:29:15,960
Speaker 4: So so a lot of people will say, oh I

573
00:29:16,040 --> 00:29:19,160
Speaker 4: feel bad when I cut the grass, it may not

574
00:29:19,360 --> 00:29:21,520
Speaker 4: actually be that. And most of us have Saint Augustine,

575
00:29:21,760 --> 00:29:23,920
Speaker 4: you know, around you know, that's the most common grass,

576
00:29:24,400 --> 00:29:27,480
Speaker 4: but it's actually sometimes if you're if you don't have

577
00:29:27,560 --> 00:29:29,360
Speaker 4: a good harm and you have a lot of you know,

578
00:29:29,480 --> 00:29:32,320
Speaker 4: bermuda or some other wild grasses in there, that is

579
00:29:32,360 --> 00:29:35,200
Speaker 4: what is causing the symptoms. And then sometimes one of

580
00:29:35,240 --> 00:29:37,920
Speaker 4: the other tricks, because it rains so much here, sometimes

581
00:29:38,240 --> 00:29:42,000
Speaker 4: these broad leaf grasses grow mold on them. And so

582
00:29:42,680 --> 00:29:46,239
Speaker 4: even though Saint Augustine doesn't pollinate, it's when you're when

583
00:29:46,280 --> 00:29:48,080
Speaker 4: it's being cut, you're pouring off.

584
00:29:48,000 --> 00:29:50,120
Speaker 5: A lot of mold. Oh well, and that would be

585
00:29:50,200 --> 00:29:51,080
Speaker 5: what's the reacting to.

586
00:29:51,360 --> 00:29:52,640
Speaker 3: And then we move to the weeds.

587
00:29:52,880 --> 00:29:56,400
Speaker 2: You have ragweed first, and pig weed then marsh elder

588
00:29:56,720 --> 00:29:58,800
Speaker 2: I've always heard of, you know, ragweed is one of

589
00:29:58,840 --> 00:30:00,160
Speaker 2: the things that a lot of people will tell you

590
00:30:00,600 --> 00:30:01,600
Speaker 2: they're allergic to.

591
00:30:02,400 --> 00:30:05,640
Speaker 5: Is that the number one ragweed is the number one.

592
00:30:05,680 --> 00:30:09,200
Speaker 4: And also just historically, you know, whenever they show pictures

593
00:30:09,240 --> 00:30:14,040
Speaker 4: on the news, the ragweed pollen looks like the spike ball,

594
00:30:14,480 --> 00:30:17,600
Speaker 4: so it's very sort of photogenic and look something like

595
00:30:17,720 --> 00:30:19,920
Speaker 4: something you know to attack you. And so that's why

596
00:30:20,080 --> 00:30:24,360
Speaker 4: ragweed is the most known fall pollen. And the way

597
00:30:24,560 --> 00:30:28,040
Speaker 4: I listed those things was spring, summer, and fall. So

598
00:30:28,160 --> 00:30:31,400
Speaker 4: in the broad sense, trees are typically in spring, except

599
00:30:31,560 --> 00:30:35,040
Speaker 4: cedar and elm, which are from fall. Grasses are on summer,

600
00:30:35,800 --> 00:30:39,760
Speaker 4: and then weeds on fall. So that was, you know,

601
00:30:40,440 --> 00:30:43,800
Speaker 4: the listing of how I did you know or going

602
00:30:43,840 --> 00:30:45,080
Speaker 4: to be tested people for allergies.

603
00:30:45,160 --> 00:30:46,960
Speaker 2: I want to skip past modes and come back to

604
00:30:47,040 --> 00:30:49,440
Speaker 2: it in a moment and go to foods. That's one

605
00:30:49,480 --> 00:30:51,840
Speaker 2: of the things that a lot of people feel that

606
00:30:52,000 --> 00:30:55,760
Speaker 2: they have an allergy to. And I noted, you've got milk, eggs,

607
00:30:55,840 --> 00:30:59,920
Speaker 2: soy peanut. I read recently that we didn't have peanut

608
00:31:00,000 --> 00:31:02,640
Speaker 2: allergies one hundred years ago, and the reason is because

609
00:31:02,680 --> 00:31:05,840
Speaker 2: one of the vaccines we take as children affects us.

610
00:31:06,080 --> 00:31:09,200
Speaker 2: And it's not the peanut we're allowed we're allergic to.

611
00:31:09,680 --> 00:31:10,840
Speaker 2: It's the copper in it.

612
00:31:11,080 --> 00:31:12,560
Speaker 3: Do you believe there's anything to that.

613
00:31:15,120 --> 00:31:16,000
Speaker 5: I don't think so.

614
00:31:17,000 --> 00:31:19,840
Speaker 4: And the reason for that is because you can have

615
00:31:20,360 --> 00:31:26,800
Speaker 4: microscopic amounts of peanut and you react to the protein.

616
00:31:27,520 --> 00:31:32,920
Speaker 4: Now there's more chance that it is the hygiene because

617
00:31:32,920 --> 00:31:36,360
Speaker 4: if you look so so if you look at the

618
00:31:36,960 --> 00:31:43,160
Speaker 4: again in India and let's say in China, so it's

619
00:31:43,200 --> 00:31:45,720
Speaker 4: it's interesting, right, they don't have much peanut allergy.

620
00:31:46,240 --> 00:31:48,840
Speaker 5: And again in India, it's because when you.

621
00:31:49,000 --> 00:31:52,479
Speaker 4: Have more of you know, the dirt and those kind

622
00:31:52,520 --> 00:31:56,120
Speaker 4: of things, you are suppressing this arm of the immune system,

623
00:31:56,680 --> 00:32:02,200
Speaker 4: so it's not trying to react to those foods. In China,

624
00:32:02,840 --> 00:32:06,600
Speaker 4: per capita, they probably eat the most peanuts that anyone

625
00:32:07,160 --> 00:32:09,560
Speaker 4: does in the world, but they have very low no

626
00:32:09,720 --> 00:32:14,440
Speaker 4: peanut allergies, and partially it's because they eat boiled peanuts.

627
00:32:15,360 --> 00:32:19,880
Speaker 4: When you boil a peanut, you denature that antigen that

628
00:32:20,440 --> 00:32:25,040
Speaker 4: people tend to get allergic to, whereas roasting a peanut

629
00:32:25,920 --> 00:32:29,280
Speaker 4: brings the antigen that you react to perfectly on the surface.

630
00:32:29,640 --> 00:32:31,280
Speaker 3: But I like them roasted so much better.

631
00:32:31,360 --> 00:32:35,400
Speaker 5: Dot I know, I know, but that's part of the thing.

632
00:32:36,040 --> 00:32:39,880
Speaker 5: And even now they tend you know, incorporating some of

633
00:32:39,960 --> 00:32:41,200
Speaker 5: those foods early.

634
00:32:41,640 --> 00:32:43,960
Speaker 4: You know, now the new guidelines are that you know,

635
00:32:44,000 --> 00:32:47,040
Speaker 4: if the child is not allergic to the food, you

636
00:32:47,240 --> 00:32:51,680
Speaker 4: incorporate some of that stuff much earlier, right, and that

637
00:32:51,960 --> 00:32:55,320
Speaker 4: may help you not you know, react to those food.

638
00:32:55,440 --> 00:32:58,680
Speaker 2: I promised I would keep you no longer. And you

639
00:32:58,840 --> 00:33:01,320
Speaker 2: have been wonderful. Doctor Chris Colosso c O.

640
00:33:01,560 --> 00:33:05,040
Speaker 3: L L A c O Advanced Asthma and allergy.

641
00:33:05,160 --> 00:33:10,000
Speaker 2: He's he's been a magic uh maker for my wife

642
00:33:10,160 --> 00:33:13,480
Speaker 2: and now he's my doctor. And obviously you can see

643
00:33:13,480 --> 00:33:16,880
Speaker 2: why he has. He's passionate about this and I hate allergies.

644
00:33:17,040 --> 00:33:19,680
Speaker 2: Thank you for being our guests, my man, thank you

645
00:33:19,800 --> 00:33:20,160
Speaker 2: very much