1 00:00:00,640 --> 00:00:10,639 Speaker 1: Welcome to Stuff You Should Know Fromhouse Stuff Works dot com. Hey, 2 00:00:10,680 --> 00:00:13,720 Speaker 1: and welcome to the podcast. I'm Josh Clark with Charles W. 3 00:00:13,920 --> 00:00:18,840 Speaker 1: Chuck Bryant y. Yeah, and this is Stuff you should Know. 4 00:00:19,160 --> 00:00:26,840 Speaker 1: It sounded uh sardonic, yery yi j a silent yawking, yawking. 5 00:00:27,640 --> 00:00:30,040 Speaker 1: I'd never get sick of that movie. No, it's a 6 00:00:30,080 --> 00:00:32,200 Speaker 1: good one. I haven't seen the second one. Don't really 7 00:00:32,200 --> 00:00:35,720 Speaker 1: intend to, but I'm afraid too, Yeah, because it might 8 00:00:35,760 --> 00:00:39,040 Speaker 1: tarnish my love of that character, because I've heard it's 9 00:00:39,040 --> 00:00:40,879 Speaker 1: not very funny to just keep it keep it with 10 00:00:40,960 --> 00:00:43,840 Speaker 1: the first one. I'm totally gonna watch him just waiting 11 00:00:43,840 --> 00:00:47,160 Speaker 1: for cable. Oh yeah, yeah, Yeah, TBS knows what they're 12 00:00:47,200 --> 00:00:51,120 Speaker 1: doing with movies that were for the big screen. Yeah, 13 00:00:51,920 --> 00:00:58,280 Speaker 1: size them down, best start ever. Uh. So you're doing good. 14 00:00:58,560 --> 00:01:03,480 Speaker 1: I'm great, Okay, good. Um. So we're talking today about 15 00:01:03,960 --> 00:01:11,960 Speaker 1: IVF in vitro fertilization. Um. And I have to say, Chuckers, 16 00:01:12,080 --> 00:01:13,560 Speaker 1: I don't really have by the way, I don't have 17 00:01:13,600 --> 00:01:18,080 Speaker 1: an intro for this one to um, although I do 18 00:01:18,200 --> 00:01:20,679 Speaker 1: have a bit of one. All right, let's see uh 19 00:01:20,760 --> 00:01:26,319 Speaker 1: in nineteen In two thousand thirteen, a lady named Louise 20 00:01:26,400 --> 00:01:33,320 Speaker 1: Brown celebrated her thirty fifth birthday, and with her birthday 21 00:01:33,319 --> 00:01:36,240 Speaker 1: coming and going, she announced that she was pregnant with 22 00:01:36,240 --> 00:01:40,400 Speaker 1: her second child. This is like mind blowing crazy stuff 23 00:01:40,440 --> 00:01:44,000 Speaker 1: all over the place, because Louise Brown was the first 24 00:01:44,959 --> 00:01:50,400 Speaker 1: human being ever conceived using in vitro fertilization. Yes, they 25 00:01:50,400 --> 00:01:52,680 Speaker 1: called them test two babies back then. Remember that. Yeah, 26 00:01:52,840 --> 00:01:55,600 Speaker 1: totally test two babies. You don't call it that anymore. No, 27 00:01:55,720 --> 00:01:58,680 Speaker 1: we've gotten a little more scientific as a society since 28 00:01:58,720 --> 00:02:02,800 Speaker 1: the seventies. Plus. I don't think they use test tubes. Yeah, 29 00:02:02,880 --> 00:02:06,360 Speaker 1: if they ever did, I think maybe petri dishes, culture dishes, 30 00:02:07,680 --> 00:02:10,360 Speaker 1: not test twos, but you know culture dish baby. It's right, 31 00:02:10,520 --> 00:02:12,680 Speaker 1: that's weird. Test tube baby. It kind of rolls off 32 00:02:12,680 --> 00:02:14,919 Speaker 1: the tongue. It's got the two T sounds, which makes 33 00:02:14,919 --> 00:02:19,320 Speaker 1: it a little funny ish and um intriguing. But that's 34 00:02:19,360 --> 00:02:21,200 Speaker 1: what she was. She was the first test two baby. 35 00:02:21,280 --> 00:02:25,959 Speaker 1: It was eight in England, um, and she was born July. 36 00:02:26,840 --> 00:02:30,800 Speaker 1: I think, um, like just a few days later. I 37 00:02:30,840 --> 00:02:35,399 Speaker 1: think the second IVF baby was born in India very 38 00:02:35,480 --> 00:02:38,639 Speaker 1: in very short order. For two. I'm sure that their 39 00:02:38,760 --> 00:02:41,520 Speaker 1: doctors were like come on, will you give birth already? 40 00:02:41,560 --> 00:02:43,839 Speaker 1: I want to be the first. Nobody remembers number two. 41 00:02:43,919 --> 00:02:46,600 Speaker 1: And then the following year, in nineteen seventy nine, the 42 00:02:46,600 --> 00:02:51,040 Speaker 1: first American IVF baby was born. And that's the history 43 00:02:51,240 --> 00:02:55,160 Speaker 1: of IVF, like it just goes back that far. Since then, 44 00:02:56,000 --> 00:03:00,000 Speaker 1: I think thirty five more than thirty five million uh 45 00:03:00,200 --> 00:03:03,880 Speaker 1: IVF babies have been born a couple of hundred thousand 46 00:03:03,919 --> 00:03:07,520 Speaker 1: each year in the US alone. Now, yeah, it was 47 00:03:07,560 --> 00:03:09,760 Speaker 1: like in the sixties eighties. Now it's up to like 48 00:03:09,800 --> 00:03:12,680 Speaker 1: a hundred and something a hundred and change. I think 49 00:03:13,520 --> 00:03:17,600 Speaker 1: I got over two thousands. Do you really really? I 50 00:03:17,680 --> 00:03:24,200 Speaker 1: saw two thousand twelve or maybe maybe two d thousand worldwide. 51 00:03:24,600 --> 00:03:26,920 Speaker 1: All right, let's just settle on that. I'll bite on 52 00:03:27,000 --> 00:03:30,200 Speaker 1: that one. Um. But yeah, that's a lot of babies 53 00:03:30,200 --> 00:03:34,880 Speaker 1: that are born through IVF, and it's a it's crazy 54 00:03:34,960 --> 00:03:39,520 Speaker 1: how the thing that struck me and finally we're getting 55 00:03:39,560 --> 00:03:43,320 Speaker 1: to the end of the intro um is that what 56 00:03:43,480 --> 00:03:46,320 Speaker 1: I v F is? It seems so like whiz bang 57 00:03:46,480 --> 00:03:51,920 Speaker 1: crazy futuristic. No, it's it's figuring out. We figured out 58 00:03:52,000 --> 00:03:58,120 Speaker 1: how a woman becomes pregnant and figured out the ways 59 00:03:58,160 --> 00:04:02,000 Speaker 1: that we could possibly best help that process along, and 60 00:04:02,640 --> 00:04:05,560 Speaker 1: that's what it is. Yeah, it's really there's no like 61 00:04:05,640 --> 00:04:09,600 Speaker 1: crazy new technology. They don't like like buzz her with 62 00:04:09,680 --> 00:04:14,800 Speaker 1: like a prey goo laser, nothing like that. It's strictly 63 00:04:14,840 --> 00:04:20,400 Speaker 1: like catheters and timing and you know, hormones. It's crazy 64 00:04:20,440 --> 00:04:23,880 Speaker 1: how simple it is. But it's also equally crazy that 65 00:04:23,960 --> 00:04:26,600 Speaker 1: you know, it's as successful as it is considering what 66 00:04:26,640 --> 00:04:32,240 Speaker 1: it What in vitro fertilization consists of. Yes, I guess 67 00:04:32,279 --> 00:04:34,960 Speaker 1: we can go ahead and talk about success rates. Um. 68 00:04:34,960 --> 00:04:37,559 Speaker 1: In the US, women under the age of thirty five 69 00:04:38,040 --> 00:04:40,640 Speaker 1: have a thirty to thirty five chance of conceiving with 70 00:04:40,680 --> 00:04:46,560 Speaker 1: ibf uh. It drops between thirty five and forty six 71 00:04:47,520 --> 00:04:53,839 Speaker 1: over forty uh. And that is percentages of live birth cycle, 72 00:04:53,960 --> 00:04:57,400 Speaker 1: which is yeah, per cycle. So like, if you go 73 00:04:57,480 --> 00:05:00,400 Speaker 1: through a cycle of in vitro fertilization, do you have 74 00:05:00,520 --> 00:05:04,039 Speaker 1: the percentage chance typically which is pretty much in lock 75 00:05:04,160 --> 00:05:09,440 Speaker 1: step with natural birth rates according to age it Yeah, well, 76 00:05:09,440 --> 00:05:12,159 Speaker 1: I mean it definitely decreases with age, but I'm not 77 00:05:12,200 --> 00:05:14,679 Speaker 1: saying it's like one for one. Sure, yeah, yeah, it's totally, 78 00:05:14,839 --> 00:05:21,080 Speaker 1: But I'm saying that I think the depreciation of possibility. 79 00:05:21,400 --> 00:05:25,520 Speaker 1: It goes down with age naturally as well with IVF two. Yeah, 80 00:05:25,560 --> 00:05:29,479 Speaker 1: and live birth is the key here because many times, uh, 81 00:05:29,960 --> 00:05:32,279 Speaker 1: there will be conception and there will be a pregnancy, 82 00:05:32,400 --> 00:05:34,560 Speaker 1: but any number of things can go wrong from there. 83 00:05:34,680 --> 00:05:40,120 Speaker 1: Oh yeah sure. Chemical pregnancies UM topic pregnant topic pregnancies. Apparently, 84 00:05:40,160 --> 00:05:43,040 Speaker 1: some Chinese researcher did a survey of a hundred thousand 85 00:05:43,120 --> 00:05:49,080 Speaker 1: plus live IVF births UM and found that there's a correlation. 86 00:05:50,480 --> 00:05:52,840 Speaker 1: You were three times likelier to have a major birth 87 00:05:52,839 --> 00:05:57,680 Speaker 1: effect if you were born via in vitro fertilization than natural. 88 00:05:57,800 --> 00:06:01,200 Speaker 1: And he just found a correlation. Um, not a cause, 89 00:06:01,360 --> 00:06:06,520 Speaker 1: but just the numbers. For some reason spit that out. Yeah. Well, now, 90 00:06:07,279 --> 00:06:08,880 Speaker 1: one of the new things you can do is up 91 00:06:08,920 --> 00:06:10,960 Speaker 1: for at a certain point in the process pg D, 92 00:06:11,520 --> 00:06:15,839 Speaker 1: which is preimplantation genetic diagnosis. And this is a test 93 00:06:15,960 --> 00:06:20,719 Speaker 1: that will cost you several thousand dollars and it basically UM. 94 00:06:20,760 --> 00:06:23,800 Speaker 1: It allows you to root out certain mono genetic disorders, 95 00:06:23,839 --> 00:06:26,360 Speaker 1: like you can get PGD testing and find out if 96 00:06:27,160 --> 00:06:29,679 Speaker 1: the baby might have like sickle cell or Huntington's disease 97 00:06:29,760 --> 00:06:33,599 Speaker 1: or cystic like process or downs and then UM you 98 00:06:33,600 --> 00:06:35,240 Speaker 1: can make a decision at that point whether or not 99 00:06:35,279 --> 00:06:37,200 Speaker 1: you want to continue with the process. Yeah. You know, 100 00:06:37,279 --> 00:06:41,960 Speaker 1: there's a real um concern that there won't be like 101 00:06:42,040 --> 00:06:46,560 Speaker 1: that down syndrome, people will be extinct eventually because the 102 00:06:47,600 --> 00:06:51,800 Speaker 1: should have gotten so accurate. Yeah, yeah, I don't think 103 00:06:51,839 --> 00:06:54,520 Speaker 1: that will happen. Well. And there's also ethical concerns with 104 00:06:54,600 --> 00:06:57,800 Speaker 1: pg D about you know, do you do selective termination 105 00:06:57,839 --> 00:06:59,240 Speaker 1: if you can find out it's a boy and you 106 00:06:59,279 --> 00:07:01,720 Speaker 1: wanted a girl, right or um, oh I didn't want 107 00:07:01,720 --> 00:07:04,760 Speaker 1: to give brown eyes? Yeah, and I know there's a 108 00:07:04,800 --> 00:07:11,800 Speaker 1: lot of ethical yeah, associated with it, and um, it's 109 00:07:11,800 --> 00:07:14,280 Speaker 1: even more basic than that for a lot of people 110 00:07:14,320 --> 00:07:19,760 Speaker 1: to like, if you have a fertilized egg, um, or 111 00:07:19,800 --> 00:07:22,280 Speaker 1: even just an egg with the potential human life. To 112 00:07:22,320 --> 00:07:26,160 Speaker 1: some people, that destroying just the egg that that was 113 00:07:26,200 --> 00:07:30,920 Speaker 1: never fertilized is like a moral problem. Yeah. Or let's 114 00:07:30,920 --> 00:07:35,720 Speaker 1: say you, um, you have a chance of multiples, um 115 00:07:35,760 --> 00:07:38,960 Speaker 1: twins or triplets or quads or more. If you're a 116 00:07:39,000 --> 00:07:42,720 Speaker 1: certain age, that is not good and can be dangerous 117 00:07:42,960 --> 00:07:46,560 Speaker 1: for you as the mother and for the kids too. Yeah. 118 00:07:46,600 --> 00:07:48,840 Speaker 1: So at that point, um, you might have to go 119 00:07:48,880 --> 00:07:53,160 Speaker 1: through what they call selective reduction, which is choosing which 120 00:07:53,160 --> 00:07:55,440 Speaker 1: ones to go with. Well, there's a lot of pitfalls 121 00:07:55,720 --> 00:07:58,280 Speaker 1: this UM, but there's a lot of people who are 122 00:07:58,320 --> 00:08:00,280 Speaker 1: helped by it as well, and at the very least 123 00:08:00,280 --> 00:08:03,760 Speaker 1: there's a lot of people who seek the help from it. 124 00:08:03,840 --> 00:08:06,520 Speaker 1: I saw something like in this article, which I think 125 00:08:06,640 --> 00:08:08,840 Speaker 1: was written in two thousands, six or seven. Yeah, it's 126 00:08:08,840 --> 00:08:12,200 Speaker 1: a little dated. A head they said six point one 127 00:08:12,240 --> 00:08:17,840 Speaker 1: million Americans are faced with infertility, which UM, infertility is 128 00:08:17,880 --> 00:08:23,800 Speaker 1: not like Bam, you're infertile. UM, here's what's wrong with you? 129 00:08:24,240 --> 00:08:29,280 Speaker 1: Infertility be right, but it isn't always technically infertility. The 130 00:08:29,320 --> 00:08:33,640 Speaker 1: definition of infertility is that you have um gotten it 131 00:08:33,720 --> 00:08:39,000 Speaker 1: on for a year unprotected and no baby has been 132 00:08:39,040 --> 00:08:43,559 Speaker 1: produced for six months. If you're overt okay, But it 133 00:08:43,600 --> 00:08:46,760 Speaker 1: depends on the doctor. Like this article talked a lot 134 00:08:46,800 --> 00:08:48,920 Speaker 1: about well, if you've gone this far and you've done 135 00:08:48,960 --> 00:08:51,520 Speaker 1: these procedures, then they'll move you to this. A lot 136 00:08:51,520 --> 00:08:54,440 Speaker 1: of the places are fertility clinics or baby factories and 137 00:08:54,480 --> 00:08:56,960 Speaker 1: they'll you can go right to I D F if 138 00:08:57,000 --> 00:08:59,760 Speaker 1: you want to. And if they say that they believe 139 00:08:59,800 --> 00:09:03,160 Speaker 1: in so's. There's not like any hard and fast law, 140 00:09:03,840 --> 00:09:06,200 Speaker 1: you know, that's the impression. After doing this for how 141 00:09:06,240 --> 00:09:09,640 Speaker 1: many years have we been doing this? Now, after eighty 142 00:09:09,720 --> 00:09:12,920 Speaker 1: years of doing this, um, I've learned that how stuff 143 00:09:12,920 --> 00:09:16,880 Speaker 1: works article is like it deals in ideals. It's not 144 00:09:17,000 --> 00:09:19,520 Speaker 1: necessarily like this is how it works in the real world. 145 00:09:19,520 --> 00:09:22,079 Speaker 1: It's like, this is how it works according to the law. 146 00:09:22,200 --> 00:09:25,320 Speaker 1: That's true. We do our best. Yeah. Um. So, apparently 147 00:09:25,360 --> 00:09:28,200 Speaker 1: about seven point three million people UM are faced with 148 00:09:28,280 --> 00:09:31,920 Speaker 1: infertility and they turned to IVF, and IVF is far 149 00:09:31,960 --> 00:09:35,720 Speaker 1: and away the most popular form of what's called UH 150 00:09:36,160 --> 00:09:41,120 Speaker 1: assisted reproductive technology, which, as we said, sounds whiz bang 151 00:09:41,160 --> 00:09:45,960 Speaker 1: and futuristic but not necessarily Yeah, about fifty of a 152 00:09:46,160 --> 00:09:49,240 Speaker 1: r t UM methods are what they call low tech, 153 00:09:49,400 --> 00:09:53,600 Speaker 1: which is maybe we'll put you on some hormones. UM 154 00:09:53,880 --> 00:09:57,319 Speaker 1: Antibiotics apparently are a huge one, a huge stream of 155 00:09:57,320 --> 00:10:02,080 Speaker 1: for infertility. Yeah. They supposedly especial the unexplained infertility, which 156 00:10:02,120 --> 00:10:05,840 Speaker 1: affects something between ten to thirty percent of infertility cases 157 00:10:05,840 --> 00:10:09,480 Speaker 1: are just unexplained. Yeah, they're like, we there's nothing structurally 158 00:10:09,480 --> 00:10:13,199 Speaker 1: wrong with you. Your husband's sperm is fine, Like there's 159 00:10:13,400 --> 00:10:16,480 Speaker 1: we can't figure it out. Well, it made getting pregnant 160 00:10:16,559 --> 00:10:18,800 Speaker 1: isn't the easiest thing in the world. It seems that 161 00:10:18,840 --> 00:10:21,520 Speaker 1: way in the movies, but there's an explanation for things 162 00:10:21,559 --> 00:10:26,920 Speaker 1: even when it's unexplained. And because there's this whole unexplained thing, Chuck, 163 00:10:27,080 --> 00:10:30,360 Speaker 1: there's like a lot of suggestions as to you know, 164 00:10:30,400 --> 00:10:33,120 Speaker 1: what's at play. Yeah, but you're but you're right. It 165 00:10:33,200 --> 00:10:38,120 Speaker 1: is kind of like, uh, man, woman, get together, have child, 166 00:10:38,400 --> 00:10:42,000 Speaker 1: have another child, maybe a third, and like it's no problem, 167 00:10:42,600 --> 00:10:44,880 Speaker 1: like you said in the movies. Well, and especially when 168 00:10:44,920 --> 00:10:47,000 Speaker 1: age comes and you know people are getting married later. 169 00:10:47,840 --> 00:10:50,760 Speaker 1: Uh you see, you know, sixteen year will have a 170 00:10:50,760 --> 00:10:54,040 Speaker 1: baby without any problem. It's sort of weird that we've 171 00:10:55,720 --> 00:11:00,760 Speaker 1: we haven't. Things haven't changed reproductively speaking, Like people are 172 00:11:00,760 --> 00:11:03,200 Speaker 1: getting married in their mid thirties, but you can still 173 00:11:03,200 --> 00:11:08,000 Speaker 1: get pregnant when you're thirteen, And it's like has shifted. 174 00:11:08,000 --> 00:11:11,079 Speaker 1: It's not going to shift within cultural attitudes. No, no, 175 00:11:11,280 --> 00:11:15,600 Speaker 1: which is why we're like, okay, well we need technology then, right, right, 176 00:11:15,720 --> 00:11:18,640 Speaker 1: But like I said, um, about half the assisted reproductive 177 00:11:18,640 --> 00:11:22,920 Speaker 1: technology methods are low tech. Um. Klomad is a big 178 00:11:23,720 --> 00:11:26,800 Speaker 1: probably the most popular fertility drug treatment. They've been using 179 00:11:26,800 --> 00:11:29,240 Speaker 1: that since like the fifties, right, I don't know, they 180 00:11:29,320 --> 00:11:32,720 Speaker 1: say fifties, either fifty years or since the fifties. Okay, 181 00:11:32,880 --> 00:11:35,280 Speaker 1: Well it's um. It's an oral medication and it is 182 00:11:35,520 --> 00:11:39,640 Speaker 1: used to induce ovulation. And actually now men have seen 183 00:11:39,720 --> 00:11:44,360 Speaker 1: have used it to increase testosterone. Um. Because an NFL player, 184 00:11:44,960 --> 00:11:52,560 Speaker 1: UH just got banned for using chlomad for fertility because 185 00:11:52,600 --> 00:11:55,120 Speaker 1: they said it increases testosterone. So it was a performance 186 00:11:55,200 --> 00:11:58,360 Speaker 1: enhancing drug, but he was using it to try to 187 00:11:58,400 --> 00:12:01,840 Speaker 1: get pregnant. That's what he said. Oh that's not fair. Um. Yeah, 188 00:12:02,000 --> 00:12:05,040 Speaker 1: Robert mathis of the cult, so he was suspended. Um. 189 00:12:05,080 --> 00:12:08,240 Speaker 1: But clomad, with clumbad alone, you have a chance of 190 00:12:08,280 --> 00:12:12,360 Speaker 1: ovulation success and about a forty three percent chance of 191 00:12:12,440 --> 00:12:17,000 Speaker 1: pregnancy success over three cycles. And after three cycles that 192 00:12:17,120 --> 00:12:20,880 Speaker 1: number goes way down. UM. So really like it becomes 193 00:12:20,960 --> 00:12:25,160 Speaker 1: less and less probable that you'll conceive after three cycles. Yeah, 194 00:12:25,160 --> 00:12:27,160 Speaker 1: it's the same through three and then and that's just 195 00:12:27,200 --> 00:12:30,920 Speaker 1: with clomad and then after that, like what people generally 196 00:12:31,000 --> 00:12:33,000 Speaker 1: do is try a few different methods before moving on 197 00:12:33,040 --> 00:12:37,880 Speaker 1: to IVF, like just the hormones UM or what we'll 198 00:12:37,920 --> 00:12:41,800 Speaker 1: talk about now, which is uh artificial insemination, right, and 199 00:12:41,840 --> 00:12:46,720 Speaker 1: that that like um assisted reproductive technology with an umbrella term. 200 00:12:46,800 --> 00:12:50,520 Speaker 1: Artificial insemination is an umbrella term underneath the a R 201 00:12:50,600 --> 00:12:54,439 Speaker 1: t umbrella. Yeah, and it's basically any time you UM 202 00:12:54,440 --> 00:12:56,800 Speaker 1: try to give the sperm a leg up and its 203 00:12:56,920 --> 00:13:01,760 Speaker 1: race toward the egg. Yeah, it's it's inseminated artificially. In 204 00:13:01,800 --> 00:13:05,040 Speaker 1: other words, it doesn't come directly from the penis into 205 00:13:05,040 --> 00:13:08,160 Speaker 1: the vagina. Right. Why does that make you laugh? Still? 206 00:13:08,360 --> 00:13:11,200 Speaker 1: I just felt like I was in the kindergarten class 207 00:13:11,240 --> 00:13:14,960 Speaker 1: cop class. Uh. Yeah, it's when the sperm is harvested 208 00:13:15,080 --> 00:13:19,440 Speaker 1: in UM for for AI for artificial insemination, it's either 209 00:13:19,520 --> 00:13:23,320 Speaker 1: implanted intravaginal or interest cervical, so in the vagina, in 210 00:13:23,320 --> 00:13:25,559 Speaker 1: the cervics. But if you're going to put it directly 211 00:13:25,600 --> 00:13:30,839 Speaker 1: into this service or the uterus, you have to wash them. Yes, 212 00:13:32,160 --> 00:13:37,360 Speaker 1: you can't put untreated sperm into directly into the uterus 213 00:13:37,400 --> 00:13:42,920 Speaker 1: because you will have what's called uteral contraction, which apparently 214 00:13:42,960 --> 00:13:48,440 Speaker 1: is extraordinarily unpleasant. The sperm have some sort of um 215 00:13:49,040 --> 00:13:52,960 Speaker 1: it's called proto glandings. I think, yeah, that you have 216 00:13:53,080 --> 00:13:55,600 Speaker 1: to wash off the sperm. If you don't, protoglandings will 217 00:13:55,600 --> 00:13:58,880 Speaker 1: set off these contractions in the uterus exactly. So they 218 00:13:59,080 --> 00:14:01,280 Speaker 1: and I said, you or I think of at uterine 219 00:14:01,360 --> 00:14:04,880 Speaker 1: contractions they're pretty violent. Uh so yeah, you wash the 220 00:14:04,920 --> 00:14:08,360 Speaker 1: sperm and um. Not only does it remove those protoglass stuns, 221 00:14:08,520 --> 00:14:11,839 Speaker 1: it's um. It eliminates any substance it will get in 222 00:14:11,880 --> 00:14:16,000 Speaker 1: the way and make the sperm motile. And motile means 223 00:14:16,040 --> 00:14:20,120 Speaker 1: they're good swimmers. Right. That's another another advantage of using 224 00:14:20,200 --> 00:14:24,480 Speaker 1: artificial inscimination, as you can say, uh, you're cut, you're cut. 225 00:14:24,920 --> 00:14:27,640 Speaker 1: You made the team, you're cut, and then you put 226 00:14:27,680 --> 00:14:30,800 Speaker 1: together this dream team of the best firm and you say, 227 00:14:31,120 --> 00:14:34,600 Speaker 1: go get them. That's right. Right, So, if you're using 228 00:14:34,640 --> 00:14:37,560 Speaker 1: the wash sperm and directly onto the uterus, that's called 229 00:14:37,600 --> 00:14:41,320 Speaker 1: I ui intra uterine instimonation. Uh. And that's just kind 230 00:14:41,320 --> 00:14:44,680 Speaker 1: of one step further than Hey, I like artificial instimination. 231 00:14:44,720 --> 00:14:46,760 Speaker 1: You can do the turkey based method at home, sure 232 00:14:46,880 --> 00:14:50,320 Speaker 1: if you want. So that's a thing. Yeah, like they 233 00:14:50,360 --> 00:14:53,360 Speaker 1: have kids. That's a form of artificial insemination. That is 234 00:14:53,440 --> 00:14:58,720 Speaker 1: artificial instamonation. Yeah, but I mean it's an umbrella term. 235 00:14:58,760 --> 00:15:00,920 Speaker 1: Well yeah, if you're using the key based her at home, 236 00:15:01,000 --> 00:15:04,760 Speaker 1: you're you're artificially inseminating but you're probably inserting it directly 237 00:15:04,800 --> 00:15:08,480 Speaker 1: into the vagina. Maybe the cervix. You're not doing intra 238 00:15:08,600 --> 00:15:13,000 Speaker 1: uterine you can't do unless you have a sperm washer, right, 239 00:15:14,520 --> 00:15:16,720 Speaker 1: which you can afford one of those these days, you know, 240 00:15:16,920 --> 00:15:20,000 Speaker 1: that's right. So if those fail, then your next step 241 00:15:20,080 --> 00:15:22,640 Speaker 1: is is probably gonna be IBF. But like I said, 242 00:15:22,680 --> 00:15:25,760 Speaker 1: depending on your age and what's going on, you can 243 00:15:26,000 --> 00:15:28,560 Speaker 1: skip straight to ib F if your doctor says that's okay, 244 00:15:28,720 --> 00:15:31,640 Speaker 1: well we'll skip straight to IVF after a message break. 245 00:15:31,640 --> 00:15:44,640 Speaker 1: How about that? All right, So let's talk about the 246 00:15:44,640 --> 00:15:50,200 Speaker 1: IVF process. Huh yeah, again, pretty low tech, high tech stuff. 247 00:15:50,240 --> 00:15:53,080 Speaker 1: It's neat. Yeah, it will cost you about twelve grand 248 00:15:53,560 --> 00:15:57,120 Speaker 1: I saw. Yeah. I mean that's a I hate the 249 00:15:57,200 --> 00:16:01,480 Speaker 1: ranges for these procedures because it really it depends on 250 00:16:01,520 --> 00:16:03,600 Speaker 1: where you are and if you have insurance. I think 251 00:16:03,640 --> 00:16:07,320 Speaker 1: fifteen states require insurance to cover it. Um. You know. 252 00:16:07,880 --> 00:16:12,600 Speaker 1: Let me interject here. There's an argument that the lack 253 00:16:12,760 --> 00:16:18,800 Speaker 1: of standards in pricing for medical procedures is the single 254 00:16:19,600 --> 00:16:23,280 Speaker 1: problem for why the health care system in the US 255 00:16:23,400 --> 00:16:27,120 Speaker 1: is broken. Yeah, that it's not necessarily insurance, that it's 256 00:16:27,120 --> 00:16:31,120 Speaker 1: not necessarily chronic disease that it is. If you came 257 00:16:31,200 --> 00:16:34,760 Speaker 1: up with standard pricing, yeah, you could solve quite a 258 00:16:34,760 --> 00:16:37,920 Speaker 1: bit of the car mechanics. Yeah, that's supposed to be 259 00:16:38,000 --> 00:16:40,480 Speaker 1: a standard. Yes, I always I never knew that with 260 00:16:40,520 --> 00:16:43,760 Speaker 1: car mechanics. If you um, when they say how much 261 00:16:43,800 --> 00:16:46,200 Speaker 1: time it takes, it's really not how they don't time 262 00:16:46,280 --> 00:16:49,120 Speaker 1: how long it takes. There's a manual that says, you know, 263 00:16:49,680 --> 00:16:52,520 Speaker 1: changing a carburetor is one point five hours. I didn't 264 00:16:52,520 --> 00:16:55,800 Speaker 1: know that. Yeah, I just know that Mr Goodbrand's posts 265 00:16:55,920 --> 00:17:01,800 Speaker 1: is on the board him like McDonald's what like oh 266 00:17:01,840 --> 00:17:05,879 Speaker 1: a menu. Yeah. Anyway, I agree with you about the 267 00:17:06,160 --> 00:17:08,160 Speaker 1: medical standards, and it makes a lot of sense. I mean, 268 00:17:09,119 --> 00:17:12,479 Speaker 1: chronic disease is a huge problem, especially preventable chronic disease. 269 00:17:12,920 --> 00:17:16,160 Speaker 1: But that's not the only issue here. It's the fact 270 00:17:16,200 --> 00:17:19,159 Speaker 1: that you can be charged almost literally in arm and 271 00:17:19,200 --> 00:17:23,760 Speaker 1: a leg depending on where you go. That's rights. It 272 00:17:23,760 --> 00:17:25,320 Speaker 1: will cost you some money, but if you have good 273 00:17:25,359 --> 00:17:28,160 Speaker 1: insurance then that will help out. Uh. So here are 274 00:17:28,160 --> 00:17:33,000 Speaker 1: there are basically five steps. The first is ovarian stimulation. Um, 275 00:17:33,000 --> 00:17:36,199 Speaker 1: this is when you're gonna be taking fertility drugs. Uh. 276 00:17:36,280 --> 00:17:38,960 Speaker 1: It's could be a couple of weeks of that um. 277 00:17:39,040 --> 00:17:41,600 Speaker 1: Some are oral. Sometimes you're gonna be given shots to 278 00:17:41,640 --> 00:17:43,680 Speaker 1: your wife, or if the ladies on our own should 279 00:17:43,680 --> 00:17:46,840 Speaker 1: be given shots to herself. Because the good thing about 280 00:17:46,840 --> 00:17:50,960 Speaker 1: ib F is you don't need a live man necessarily. No, 281 00:17:51,119 --> 00:17:53,280 Speaker 1: you just need the sperma. So a lot of the 282 00:17:53,520 --> 00:17:57,280 Speaker 1: could come from anywhere. Yeah, single ladies are all the 283 00:17:57,320 --> 00:18:04,840 Speaker 1: single ladies or ladies in the l g BT community. 284 00:18:04,880 --> 00:18:08,440 Speaker 1: I always want to mix up those letters. Oh yeah, 285 00:18:08,640 --> 00:18:10,840 Speaker 1: like they doesn't need to be a man involved. No, 286 00:18:11,520 --> 00:18:14,000 Speaker 1: I mean at some point, I guess if you could 287 00:18:14,000 --> 00:18:18,520 Speaker 1: grow sperm in a lab from stem cells. Not directly 288 00:18:19,400 --> 00:18:21,159 Speaker 1: technically you could do that, but no, it doesn't have 289 00:18:21,200 --> 00:18:23,440 Speaker 1: to be involved in harvest sperm from a sperm bank, 290 00:18:24,240 --> 00:18:29,560 Speaker 1: anonymous donor friend of a friend, transient who's just passing 291 00:18:29,560 --> 00:18:34,080 Speaker 1: through town, whatever your standards are. You could conceivably get 292 00:18:34,119 --> 00:18:37,120 Speaker 1: your hands on some sperm and then bam, you don't 293 00:18:37,119 --> 00:18:39,760 Speaker 1: need a man. I was it from the besket I 294 00:18:39,760 --> 00:18:42,600 Speaker 1: could get you some sperm by three pm. That is 295 00:18:42,640 --> 00:18:44,720 Speaker 1: a great movie. Man. I saw that again for the 296 00:18:44,760 --> 00:18:47,360 Speaker 1: first time in a while recently. Oh man, I think 297 00:18:47,359 --> 00:18:49,080 Speaker 1: he's talking about a big toe. I can get you 298 00:18:49,080 --> 00:18:52,560 Speaker 1: a big toe by three pm. Um. But yes, you 299 00:18:52,600 --> 00:18:54,960 Speaker 1: will need sperm if you're the husband and it's uh, 300 00:18:55,200 --> 00:18:57,639 Speaker 1: just your regular old husband and wife trying to conceive, 301 00:18:57,800 --> 00:19:00,119 Speaker 1: or just a man and woman. Then the hus and 302 00:19:00,200 --> 00:19:05,080 Speaker 1: will deposit that sperm and a little room designed to 303 00:19:05,920 --> 00:19:09,919 Speaker 1: make that happen, and then they will take the sperm 304 00:19:09,920 --> 00:19:12,000 Speaker 1: and wash it and hold it. Uh, and it's all 305 00:19:12,040 --> 00:19:15,280 Speaker 1: timed out, you know appropriately. Of course they can't hold 306 00:19:15,320 --> 00:19:18,480 Speaker 1: them to it forever. And so that's the ovarian stimulation. 307 00:19:18,520 --> 00:19:20,440 Speaker 1: Like you're trying to get the eggs to come along, 308 00:19:20,520 --> 00:19:22,880 Speaker 1: and not only are you trying to get that an 309 00:19:22,920 --> 00:19:24,639 Speaker 1: egg to come along, you're trying to get several to 310 00:19:24,680 --> 00:19:26,280 Speaker 1: come along. Yeah, that's the whole point is you want 311 00:19:26,359 --> 00:19:28,760 Speaker 1: multiple eggs, right. So you know, a woman is born 312 00:19:28,840 --> 00:19:31,800 Speaker 1: with all of the approximately four hundred thousand eggs she'll 313 00:19:31,800 --> 00:19:37,680 Speaker 1: ever produce in her life. Um down right, during her 314 00:19:38,480 --> 00:19:42,720 Speaker 1: menstrual cycle, one of those eggs enters a fallopian tube 315 00:19:42,760 --> 00:19:47,360 Speaker 1: and um it becomes mature. Right. So what these hormones 316 00:19:47,400 --> 00:19:49,720 Speaker 1: do is get a bunch of those eggs into their 317 00:19:49,720 --> 00:19:53,159 Speaker 1: fallopian rappers and get them to mature over time. And 318 00:19:53,200 --> 00:19:57,280 Speaker 1: the doctor um, I guess pays attention to how they're maturing, 319 00:19:57,640 --> 00:19:59,960 Speaker 1: and when he decides these eggs are ready to get 320 00:20:00,480 --> 00:20:02,320 Speaker 1: that's when you hit step two, which is the egg 321 00:20:02,359 --> 00:20:07,960 Speaker 1: retrieval step. That's right, and that is not super complicated either. 322 00:20:08,520 --> 00:20:13,960 Speaker 1: It's called the name sounds complicated, transvaginal ultrasound aspiration, but 323 00:20:14,040 --> 00:20:17,520 Speaker 1: what it really is is a mild sedative and a 324 00:20:17,640 --> 00:20:23,520 Speaker 1: suction device that sucks out the eggs and that's really 325 00:20:23,520 --> 00:20:26,200 Speaker 1: all there is. Do it. It's pretty amazing. Um. If 326 00:20:26,280 --> 00:20:30,520 Speaker 1: you cannot use the um TU a method, you will 327 00:20:30,840 --> 00:20:34,640 Speaker 1: have to undergo a more involved procedure called laparoscopic surgery, 328 00:20:34,680 --> 00:20:39,640 Speaker 1: which isn't super involved either. It is also a short process, 329 00:20:39,680 --> 00:20:42,879 Speaker 1: but there's a small incision in the abdomen to locate 330 00:20:42,920 --> 00:20:45,680 Speaker 1: your ovaries. Yeah, they put a little video camera in there. 331 00:20:46,640 --> 00:20:50,400 Speaker 1: So um more involved obviously because it is a surgical procedure, 332 00:20:50,440 --> 00:20:52,520 Speaker 1: but it's not like you're staying in the hospital for 333 00:20:52,520 --> 00:20:55,040 Speaker 1: a week or even right. Yeah, it's just more involved 334 00:20:55,040 --> 00:20:58,480 Speaker 1: because you have to use more anesthesia to which automatically 335 00:20:58,480 --> 00:21:03,360 Speaker 1: increases risks exactly with the other one aspiration. Yeah, uh 336 00:21:03,440 --> 00:21:06,200 Speaker 1: the uh, I guess you just need a mild seditive. 337 00:21:06,240 --> 00:21:10,840 Speaker 1: It sets here. Yeah, it's like like twilight sleep alright. 338 00:21:10,880 --> 00:21:12,720 Speaker 1: So step three, you've got your eggs. You've got your 339 00:21:12,800 --> 00:21:15,720 Speaker 1: multiple eggs. They're all looking good. Then you yeah, because 340 00:21:15,760 --> 00:21:17,399 Speaker 1: they go through and they look at them and ye 341 00:21:17,600 --> 00:21:20,280 Speaker 1: and say this one looks good. This one looks good, man, 342 00:21:20,359 --> 00:21:23,040 Speaker 1: not this one. Yeah, And I'm not sure when pg 343 00:21:23,200 --> 00:21:29,160 Speaker 1: D can take place. I think after would think yeah, yeah, 344 00:21:29,200 --> 00:21:30,879 Speaker 1: I guess it would have to be yeah, okay, that 345 00:21:30,920 --> 00:21:34,280 Speaker 1: makes sense. Um. So then you've got your insemination. And 346 00:21:34,400 --> 00:21:37,520 Speaker 1: like I said, you're you've got your sperm. However you 347 00:21:37,600 --> 00:21:42,200 Speaker 1: got it. We ain't asking whatever it was a transient 348 00:21:42,240 --> 00:21:45,480 Speaker 1: on the street, More power to you. Um. They examine 349 00:21:45,480 --> 00:21:49,760 Speaker 1: the eggs and say these look robust and juicy and full, 350 00:21:49,800 --> 00:21:52,159 Speaker 1: and these are the best ones. So we're going to 351 00:21:52,320 --> 00:21:54,639 Speaker 1: use these. And that's when the sperm is at it 352 00:21:54,640 --> 00:21:57,840 Speaker 1: and the best sperm um is picked and then it's 353 00:21:58,040 --> 00:22:00,280 Speaker 1: in a culture and it's doing its thing right. And 354 00:22:00,280 --> 00:22:04,800 Speaker 1: depending on the sperm um, they might injected directly into 355 00:22:04,880 --> 00:22:11,400 Speaker 1: the egg, which is called um oh intra citoplasmic sperm injection. 356 00:22:12,800 --> 00:22:17,080 Speaker 1: They could also just right, that's like the sperm doesn't 357 00:22:17,119 --> 00:22:19,119 Speaker 1: have to go into the egg, it gets put into 358 00:22:19,160 --> 00:22:23,440 Speaker 1: the egg um. But more traditional methods are just inserting 359 00:22:23,480 --> 00:22:26,760 Speaker 1: it into the near the egg in the culture, right, 360 00:22:27,359 --> 00:22:30,520 Speaker 1: and the culture can be artificial, but um it's also 361 00:22:30,600 --> 00:22:34,440 Speaker 1: often made of the endometrium from the woman or um 362 00:22:34,520 --> 00:22:39,440 Speaker 1: some in addition to possibly like her um uh cervical fluids. 363 00:22:40,000 --> 00:22:44,120 Speaker 1: So like it's it's basically mimicking what will what would 364 00:22:44,160 --> 00:22:46,320 Speaker 1: be going on in like the fallopian tube or something. 365 00:22:46,359 --> 00:22:48,720 Speaker 1: That's all they're doing is taking the process that normally 366 00:22:48,760 --> 00:22:52,160 Speaker 1: happens inside the woman's body and outside for a little while. 367 00:22:52,359 --> 00:22:54,280 Speaker 1: And so you've got the egg and the sperm in 368 00:22:54,320 --> 00:22:59,080 Speaker 1: the same culture and it's within possibly an hour, fertilization 369 00:22:59,119 --> 00:23:01,840 Speaker 1: might have taken place. There's an open bar, everyone's getting 370 00:23:01,840 --> 00:23:05,880 Speaker 1: to know each other, everyone's getting friendly. Little icebreaker happens, 371 00:23:06,680 --> 00:23:09,080 Speaker 1: and like you said, it can be hours when they 372 00:23:09,119 --> 00:23:13,919 Speaker 1: are doing the fertilization dance. And the next day your 373 00:23:13,960 --> 00:23:17,440 Speaker 1: doctor is gonna confirm visually that there are two pro 374 00:23:17,560 --> 00:23:22,360 Speaker 1: nuclei and that is the basis of your embryo right there. 375 00:23:23,080 --> 00:23:24,760 Speaker 1: You see that, then that means things are ahead in 376 00:23:24,800 --> 00:23:27,240 Speaker 1: the right direction because the pro nuclei from the sperm 377 00:23:27,280 --> 00:23:29,359 Speaker 1: and the pro nuclei from the egg you're gonna fuse 378 00:23:29,440 --> 00:23:35,200 Speaker 1: to make a single nuclei and that becomes the embryo, 379 00:23:35,840 --> 00:23:39,880 Speaker 1: which divides into well, that becomes the zygote I'm sorry, 380 00:23:40,240 --> 00:23:43,119 Speaker 1: which divides into two cells, and then I think by 381 00:23:43,160 --> 00:23:45,040 Speaker 1: the time it's either two or four cells, it becomes 382 00:23:45,040 --> 00:23:48,960 Speaker 1: an embryo, right, yeah, and then that's a couple of 383 00:23:49,040 --> 00:23:52,640 Speaker 1: days after fertilization. Is when you get to that stage. Yeah. Yeah, 384 00:23:52,640 --> 00:23:55,080 Speaker 1: the cell division is very slow at first, but then 385 00:23:55,119 --> 00:23:57,000 Speaker 1: it starts to pick up time. By the time you 386 00:23:57,119 --> 00:23:59,800 Speaker 1: reach day five or six, you've got what's called the 387 00:24:00,040 --> 00:24:03,960 Speaker 1: asked the system. By this time, there's um fetal tissues 388 00:24:04,000 --> 00:24:08,960 Speaker 1: growing in like uh, embryonic fluid cavity, and this thing 389 00:24:09,080 --> 00:24:14,520 Speaker 1: is yeah pretty much. Um this the doctor is not 390 00:24:14,600 --> 00:24:17,879 Speaker 1: normally gonna see this. They're gonna observe the egg, the 391 00:24:17,920 --> 00:24:21,160 Speaker 1: fertilized egg or embryo for maybe a couple of days 392 00:24:21,200 --> 00:24:23,800 Speaker 1: to make sure everything is progressing normally, and then they'll 393 00:24:23,800 --> 00:24:26,399 Speaker 1: put it back into the mom. Yeah. I mean that 394 00:24:26,480 --> 00:24:30,480 Speaker 1: can be done after one day, but um, your your 395 00:24:30,560 --> 00:24:32,680 Speaker 1: doctor that they'll have a plan of when they think 396 00:24:32,720 --> 00:24:35,960 Speaker 1: the best time is. And you're being monitored and all that. 397 00:24:36,080 --> 00:24:38,160 Speaker 1: Not you with the man, but the woman is being 398 00:24:38,160 --> 00:24:41,400 Speaker 1: monitored they don't care about the man. And then depending 399 00:24:41,840 --> 00:24:46,119 Speaker 1: depending on where they put it, that that's the type 400 00:24:46,200 --> 00:24:51,639 Speaker 1: of UM assisted reproductive technology that's being used. Right, So, 401 00:24:51,680 --> 00:24:55,040 Speaker 1: like if you're using IVF, the thing has been fertilized 402 00:24:55,080 --> 00:24:57,480 Speaker 1: outside of the womb, outside of the body, and then 403 00:24:57,600 --> 00:25:02,840 Speaker 1: introduced into the the uterus. Yeah, it's called the transfer. Yeah, 404 00:25:03,160 --> 00:25:07,200 Speaker 1: and they basically just usually catheter right, Yeah, it's UM. 405 00:25:07,200 --> 00:25:11,159 Speaker 1: It's it's suspended in fluid um to I guess, just 406 00:25:11,240 --> 00:25:13,600 Speaker 1: make it easier to get in there. It's like those 407 00:25:13,760 --> 00:25:18,560 Speaker 1: UM peanuts, the foam peanuts for shipping. It's that version exactly. 408 00:25:19,000 --> 00:25:21,399 Speaker 1: So it's suspended in the drop of fluid and it 409 00:25:21,520 --> 00:25:26,160 Speaker 1: is a long, thin cafeter and it's um placed into 410 00:25:26,200 --> 00:25:28,639 Speaker 1: the vagina, pass the cervix right there in the uterus 411 00:25:28,720 --> 00:25:32,960 Speaker 1: and squirt there it goes. And it's really that easy. 412 00:25:33,440 --> 00:25:40,240 Speaker 1: There's another process called um zygo introphallopian transfer where UM 413 00:25:40,280 --> 00:25:43,800 Speaker 1: it's the same process, but instead of depositing the fertilized 414 00:25:43,840 --> 00:25:47,760 Speaker 1: egg into the uterus, they put it into the fallopian tube. Right, 415 00:25:47,840 --> 00:25:49,680 Speaker 1: And I think that has not as great a chance 416 00:25:49,720 --> 00:25:51,600 Speaker 1: as as ib F. Is that right, I think you 417 00:25:51,760 --> 00:25:58,600 Speaker 1: try ZIFT is what it's abbreviated as UM before IVF okay, 418 00:26:00,080 --> 00:26:02,959 Speaker 1: but again all those rules are subthing to change depending 419 00:26:02,960 --> 00:26:07,000 Speaker 1: on your doctor in your situation. UM. And then your 420 00:26:07,000 --> 00:26:11,080 Speaker 1: embryo hopefully well attach to the uterine wall, uh if 421 00:26:11,119 --> 00:26:14,119 Speaker 1: it attaches. I think we said at up topic, pregnancy 422 00:26:14,320 --> 00:26:17,960 Speaker 1: is when it does not attached to the uterine wall, 423 00:26:18,040 --> 00:26:22,080 Speaker 1: but outside of the uterus, but usually the Filippian two 424 00:26:22,119 --> 00:26:24,879 Speaker 1: I think, right, it like never descends into the uterus, 425 00:26:25,119 --> 00:26:26,840 Speaker 1: and so you can't get pregnant that way, or you 426 00:26:26,880 --> 00:26:28,639 Speaker 1: can't have a kid that way. No, you can't, like 427 00:26:28,760 --> 00:26:30,960 Speaker 1: even if the kids starts to develop, you have to 428 00:26:31,080 --> 00:26:33,720 Speaker 1: terminate the pregnancy because it will kill you, that's right. 429 00:26:33,920 --> 00:26:36,640 Speaker 1: Or you can get what's called a chemical pregnancy, which 430 00:26:36,680 --> 00:26:41,399 Speaker 1: is basically just a really early miscarriage, super early in 431 00:26:41,440 --> 00:26:45,639 Speaker 1: the process chemical pregnancy. Yeah. Uh, And those are just 432 00:26:45,680 --> 00:26:48,320 Speaker 1: a couple of things that can go wrong along the way. Uh. 433 00:26:48,440 --> 00:26:50,560 Speaker 1: You know, it's a stressful time for the couples because 434 00:26:50,800 --> 00:26:54,280 Speaker 1: they're probably at there it's probably their last step towards 435 00:26:54,280 --> 00:26:58,800 Speaker 1: having a natural as they call them UM. And then 436 00:26:58,960 --> 00:27:03,280 Speaker 1: the woman is also getting injections for hormones throughout that 437 00:27:03,320 --> 00:27:06,280 Speaker 1: can be rough on on the lady as well. I 438 00:27:06,280 --> 00:27:11,520 Speaker 1: can imagine so um, in addition to being infected with hormones, 439 00:27:11,560 --> 00:27:16,160 Speaker 1: having your eggs harvested, getting laproscopic surgery like um, your 440 00:27:16,240 --> 00:27:18,960 Speaker 1: husband being in a room where he has to ejaculate 441 00:27:19,040 --> 00:27:22,120 Speaker 1: into a cup and like all of this stuff, Um, 442 00:27:22,160 --> 00:27:26,600 Speaker 1: there are actual risks involved, like physical risks. So like 443 00:27:26,640 --> 00:27:29,320 Speaker 1: we said with if you get the laproscopic surgery, when 444 00:27:29,320 --> 00:27:32,200 Speaker 1: your eggs are harvested, UM, like you have the risk 445 00:27:32,359 --> 00:27:34,960 Speaker 1: that comes from any kind of anesthesia, any kind of 446 00:27:35,000 --> 00:27:41,800 Speaker 1: surgery like that. So um there are things like chest pains, um. 447 00:27:41,920 --> 00:27:45,920 Speaker 1: What else. Well, there's one risk called o h s 448 00:27:45,920 --> 00:27:49,720 Speaker 1: S Ovarian hyper stimulation syndrome, and that's when you're overari 449 00:27:49,880 --> 00:27:54,280 Speaker 1: swell up, which is super painful and about of patients 450 00:27:54,400 --> 00:27:58,679 Speaker 1: UM experience that. But it can range from mild cases 451 00:27:58,680 --> 00:28:01,120 Speaker 1: where you just take over the countermens two more severe 452 00:28:01,160 --> 00:28:05,119 Speaker 1: cases UM moderate to severe where you know gas and 453 00:28:05,160 --> 00:28:08,600 Speaker 1: alge and vomiting and no appetite. Uh. And I think 454 00:28:08,600 --> 00:28:13,600 Speaker 1: only one to two of women experienced severe ohss. That 455 00:28:13,840 --> 00:28:16,480 Speaker 1: means you're probably gonna gonna go to hospital, gain a 456 00:28:16,520 --> 00:28:19,280 Speaker 1: lot of weight, like things that women don't like. And 457 00:28:19,280 --> 00:28:25,040 Speaker 1: and that's the result of those fertility drugs, like the ovaries. Like, whoa, whoa, 458 00:28:25,080 --> 00:28:28,480 Speaker 1: I did not sign up for this. You're over stimulating 459 00:28:28,520 --> 00:28:31,840 Speaker 1: me and I'm fighting back pretty much. Um. But yeah, 460 00:28:31,840 --> 00:28:34,080 Speaker 1: it's it does sound like it's fairly common, at least 461 00:28:34,080 --> 00:28:36,640 Speaker 1: in a mild form, and it's in the mildest form 462 00:28:36,680 --> 00:28:40,280 Speaker 1: apparently it clears up on its own. Um. So then, 463 00:28:42,080 --> 00:28:44,480 Speaker 1: like I said, with a retrieval, you have the general 464 00:28:45,120 --> 00:28:51,000 Speaker 1: anesthetic issue. Um. And then even with the lighter aspiration procedure, Uh, 465 00:28:51,120 --> 00:28:54,680 Speaker 1: there's still problems. Like you can get an infection, Um, 466 00:28:54,760 --> 00:29:00,000 Speaker 1: you can have structural damage. But speaking of structural damage, um, 467 00:29:00,120 --> 00:29:04,880 Speaker 1: in addition to in vido fertilization, you could also try surgery. 468 00:29:05,000 --> 00:29:08,200 Speaker 1: That's another avenue that some people try to UM solve 469 00:29:08,240 --> 00:29:12,280 Speaker 1: their infertility. Like if you have if your fallopian tube 470 00:29:12,320 --> 00:29:14,480 Speaker 1: is blocked or whatever, they can go in and yeah, yeah, 471 00:29:14,480 --> 00:29:18,240 Speaker 1: like if you have a physical problem. Yeah. So chuckers, 472 00:29:18,280 --> 00:29:22,720 Speaker 1: we already mentioned ZIFT. Have you heard a gift? I 473 00:29:22,800 --> 00:29:29,440 Speaker 1: have gamme eat inter phallopian transfer similar to IVF, but um, 474 00:29:29,480 --> 00:29:32,360 Speaker 1: it's in the fallopian tubes. Now, what's the difference between 475 00:29:32,400 --> 00:29:35,800 Speaker 1: XIFT and GIFT? Then okay, I'll explain. Oh wait, wait, 476 00:29:35,960 --> 00:29:39,400 Speaker 1: Ziff is in a lab. Gift is in the Philippian tubes. Yeah, 477 00:29:39,480 --> 00:29:43,000 Speaker 1: like you go in and and artificially inseminate the egg 478 00:29:43,280 --> 00:29:46,720 Speaker 1: in the fallopian tube. Okay, that makes sense. Yeah, but 479 00:29:46,880 --> 00:29:49,080 Speaker 1: if you have damage phallopian tubes, you can't use the 480 00:29:49,120 --> 00:29:52,920 Speaker 1: gift method. But that the Gift method, the advantage of 481 00:29:52,920 --> 00:29:57,240 Speaker 1: it is much much more closely mimics natural birth or 482 00:29:57,320 --> 00:30:02,280 Speaker 1: natural pregnancy because the egg is inseminated in the fallopian 483 00:30:02,360 --> 00:30:04,800 Speaker 1: tube and then it just goes about its normal process 484 00:30:04,840 --> 00:30:07,920 Speaker 1: from there. Yes, so aside from having sperm introduced through 485 00:30:07,920 --> 00:30:11,800 Speaker 1: a needle, it's totally natural. But it's not used. It's 486 00:30:11,800 --> 00:30:15,280 Speaker 1: only like two of cases, and I think Ziff is 487 00:30:15,320 --> 00:30:17,240 Speaker 1: only one percent. Yeah, I saw even less than I 488 00:30:17,240 --> 00:30:18,960 Speaker 1: saw that. Both of them are less than one percent. 489 00:30:19,040 --> 00:30:23,440 Speaker 1: And the big blockbusters in vitro fertilization. Uh. And then 490 00:30:23,440 --> 00:30:27,600 Speaker 1: there's something called I C S I UH intra cytoplasmic 491 00:30:27,600 --> 00:30:31,320 Speaker 1: sperm injection and that's a treatment that you'll do alongside IBF. 492 00:30:32,000 --> 00:30:35,280 Speaker 1: Remember I was saying like, depending on how the sperm 493 00:30:35,360 --> 00:30:38,240 Speaker 1: is introduced, that's one way that it might work. Yeah. 494 00:30:38,240 --> 00:30:41,360 Speaker 1: At about cases, I think they use the the I 495 00:30:41,440 --> 00:30:45,440 Speaker 1: C S I method, and that's just injecting the sperm 496 00:30:45,560 --> 00:30:49,680 Speaker 1: basically into vegg. Well, a single sperm that's like your 497 00:30:49,720 --> 00:30:57,440 Speaker 1: sperm has problems, and so we're gonna pick out one, dude, hercules, hercules. Uh. 498 00:30:57,440 --> 00:31:01,840 Speaker 1: And the cool thing about IVF is literally, yeah, if 499 00:31:01,840 --> 00:31:06,160 Speaker 1: you have multiple eggs um that are really great, um, 500 00:31:06,240 --> 00:31:08,680 Speaker 1: you can freeze the ones you don't use, and if 501 00:31:08,680 --> 00:31:10,440 Speaker 1: you want to go back for round two, you can 502 00:31:10,520 --> 00:31:14,280 Speaker 1: skip the first part of the harvesting and go directly 503 00:31:14,320 --> 00:31:17,440 Speaker 1: to uh, the next steps. Yeah, I guess you could 504 00:31:17,440 --> 00:31:20,120 Speaker 1: skip all the hormones and all of the possible over 505 00:31:20,160 --> 00:31:23,240 Speaker 1: stimulation of ovary. Yeah, the initial hormones, but you still 506 00:31:23,240 --> 00:31:25,760 Speaker 1: have the ones on the backside. That it's being able 507 00:31:25,800 --> 00:31:27,760 Speaker 1: to skip that that first bed is a big relief 508 00:31:27,760 --> 00:31:29,840 Speaker 1: to a lot of women, I can imagine. Yeah. Yeah, 509 00:31:30,240 --> 00:31:34,520 Speaker 1: I'm sure it's worth the expense too. Ut freezing Yeah yeah. 510 00:31:34,960 --> 00:31:38,960 Speaker 1: So um. What's crazy about all this chuck is that 511 00:31:39,440 --> 00:31:42,280 Speaker 1: not all insurance covers this. A lot of insurance treats 512 00:31:42,800 --> 00:31:48,600 Speaker 1: UM IVF procedures as an elective procedure. UM. As a result, 513 00:31:48,760 --> 00:31:51,320 Speaker 1: some states, I think fifteen states have laws on the 514 00:31:51,360 --> 00:31:55,040 Speaker 1: book saying if you're an insurance company operating in our state, 515 00:31:55,120 --> 00:31:59,200 Speaker 1: you have to at the very least cover infertility treatments. Yeah, 516 00:31:59,240 --> 00:32:01,880 Speaker 1: and I mean just check with your insurance if you're interested. 517 00:32:02,360 --> 00:32:06,240 Speaker 1: They may cover some but not all. UM, but you'll 518 00:32:06,240 --> 00:32:10,000 Speaker 1: probably get some assistance, you hope. Yeah, Or you can 519 00:32:10,040 --> 00:32:12,520 Speaker 1: just move to a state like Massachusetts that has like 520 00:32:13,320 --> 00:32:17,920 Speaker 1: UM law. Yeah. Basically the law is like you cover 521 00:32:18,080 --> 00:32:22,280 Speaker 1: ivfly they have right, they have the best some of 522 00:32:22,320 --> 00:32:25,520 Speaker 1: the best IVF doctors up there. Yeah. I read an 523 00:32:25,600 --> 00:32:28,760 Speaker 1: article that interviewed this one couple and they were like, 524 00:32:28,960 --> 00:32:32,040 Speaker 1: what some state that didn't have any insurance laws about 525 00:32:32,120 --> 00:32:34,920 Speaker 1: IVF and they moved to Massachusetts, and they said it 526 00:32:34,960 --> 00:32:38,240 Speaker 1: was like going from a place, going from a hospital 527 00:32:38,280 --> 00:32:41,280 Speaker 1: that didn't even have X ray technology going into like 528 00:32:41,320 --> 00:32:44,719 Speaker 1: the most cutting edge type of hospital you could possibly imagine, 529 00:32:44,760 --> 00:32:49,600 Speaker 1: just because because it's required there. The doctors by nature 530 00:32:50,080 --> 00:32:52,200 Speaker 1: are all just experts at it because they've done so 531 00:32:52,280 --> 00:32:55,360 Speaker 1: much work on it. They're trying to make little baby liberals, right, 532 00:32:56,000 --> 00:32:59,640 Speaker 1: little take Kennedy tone and around you anything else. I 533 00:32:59,680 --> 00:33:02,480 Speaker 1: got a thing else. So let's speed the couples out 534 00:33:02,480 --> 00:33:05,280 Speaker 1: there going through this stuff. Yeah, God's being good luck. Yeah, 535 00:33:05,400 --> 00:33:08,120 Speaker 1: we wish you well. Um, and if you want to 536 00:33:08,200 --> 00:33:11,240 Speaker 1: learn even more about this, you can type in vitro 537 00:33:11,360 --> 00:33:14,120 Speaker 1: fertilization in the search part how stuff works dot com 538 00:33:14,160 --> 00:33:18,840 Speaker 1: and that brings up listener mail. I'm gonna call this, 539 00:33:19,240 --> 00:33:24,880 Speaker 1: uh work surveillance. Good. We did that one people employees 540 00:33:24,920 --> 00:33:28,400 Speaker 1: spying on you, the employers spying. That's just true. Hey, guys, 541 00:33:28,480 --> 00:33:33,240 Speaker 1: I work for blank company on a large shipping corporation 542 00:33:33,320 --> 00:33:37,600 Speaker 1: let's call ship Co. Yeah, ship Co for seven years. 543 00:33:38,200 --> 00:33:40,120 Speaker 1: When I started, I love the company and the job. 544 00:33:40,360 --> 00:33:43,840 Speaker 1: As things shifted more towards the bottom line oriented attitude 545 00:33:43,840 --> 00:33:45,480 Speaker 1: with the company, I start to get pretty burnt out 546 00:33:45,720 --> 00:33:47,680 Speaker 1: began looking for something else to do with my life. 547 00:33:48,120 --> 00:33:52,280 Speaker 1: I always had an intense I'm sorry, in interest, we'll say, 548 00:33:52,280 --> 00:33:56,280 Speaker 1: an intense in an electric guitars, not just as a player, 549 00:33:56,320 --> 00:33:59,400 Speaker 1: but something I studied from a historical standpoint and always 550 00:33:59,480 --> 00:34:03,320 Speaker 1: enjoy taking apart and messing with my guitars. At some 551 00:34:03,360 --> 00:34:07,480 Speaker 1: point it became interested in lutheriory and decided to become 552 00:34:07,520 --> 00:34:09,839 Speaker 1: a guitar maker. So what I ended up happening doing 553 00:34:10,200 --> 00:34:14,279 Speaker 1: Luther Yeah, like a luthier. As a guitar maker, like 554 00:34:14,360 --> 00:34:19,600 Speaker 1: a cooper makes the barrels. Yeah, wine barrels in it. Yeah, 555 00:34:19,640 --> 00:34:21,600 Speaker 1: a luthier makes a guitar. I did not know that, 556 00:34:22,320 --> 00:34:26,200 Speaker 1: l U t h I e er Uh what ended 557 00:34:26,280 --> 00:34:28,279 Speaker 1: up happening. I would finish up my workload for the 558 00:34:28,320 --> 00:34:30,120 Speaker 1: day and tidy up the store, and if there were 559 00:34:30,120 --> 00:34:32,920 Speaker 1: no customers I would work on my guitar designs at work. 560 00:34:33,560 --> 00:34:35,279 Speaker 1: For a while, the management didn't care, but as the 561 00:34:35,280 --> 00:34:37,440 Speaker 1: pressure started being put on them, they had to tell 562 00:34:37,480 --> 00:34:42,080 Speaker 1: me to stop. But I didn't because I found my passion. Finally, 563 00:34:42,120 --> 00:34:43,880 Speaker 1: one day I was pulled into the office and handed 564 00:34:43,920 --> 00:34:47,640 Speaker 1: screenshots that I hadn't taken of my guitar design work 565 00:34:48,360 --> 00:34:50,560 Speaker 1: that I was doing on the clock. So they had 566 00:34:50,560 --> 00:34:53,359 Speaker 1: a program that wasn't just sending keystroke information of their 567 00:34:53,360 --> 00:34:58,000 Speaker 1: security team, sending actual screens of everything going on on it. Yeah. 568 00:34:58,040 --> 00:35:00,160 Speaker 1: We talked about that one. Yeah, I don't remember. It's 569 00:35:00,160 --> 00:35:03,680 Speaker 1: called man. I would freak out if someone handed me screenshots. Uh. 570 00:35:03,800 --> 00:35:06,919 Speaker 1: Needless to say, I was put on disciplinary probation. Didn't 571 00:35:06,920 --> 00:35:08,840 Speaker 1: make it to the end of that because I quit 572 00:35:09,000 --> 00:35:11,200 Speaker 1: to pursue my dream and I'm happy to say that 573 00:35:11,200 --> 00:35:14,719 Speaker 1: I've been a full time professional luthier ever since. It's 574 00:35:15,640 --> 00:35:17,279 Speaker 1: one of my guitars. Is even on the cover of 575 00:35:17,280 --> 00:35:20,279 Speaker 1: a recent issue of Premier Guitar magazine that's like the 576 00:35:20,400 --> 00:35:24,440 Speaker 1: Premier Guitar Magazine. There's a second story about a robbery 577 00:35:24,480 --> 00:35:27,719 Speaker 1: that happened while I was on that probation period, but 578 00:35:27,760 --> 00:35:30,600 Speaker 1: I'll leave that for anyone curious enough to google my name. 579 00:35:32,760 --> 00:35:36,360 Speaker 1: Tantalizing all right. That is from Paul Roney R H 580 00:35:36,520 --> 00:35:39,040 Speaker 1: O N E. Y. And he says, if either one 581 00:35:39,040 --> 00:35:42,480 Speaker 1: of you guys once a handmade USA electric guitar by 582 00:35:42,480 --> 00:35:44,600 Speaker 1: a company that doesn't spile and some employees and hit 583 00:35:44,640 --> 00:35:47,080 Speaker 1: me up, I will hook you up. Wow. And I 584 00:35:47,160 --> 00:35:49,719 Speaker 1: checked them out and they're sweet. Yah. Yeah, I'm gonna 585 00:35:49,719 --> 00:35:55,080 Speaker 1: see what hook you up means and when you stuff, yeah, 586 00:35:55,120 --> 00:35:58,440 Speaker 1: we'll see. But yeah, that is from Paul Roney. And 587 00:35:58,600 --> 00:36:02,600 Speaker 1: good for you for fighting ship co. Yeah and pursuing 588 00:36:02,640 --> 00:36:06,520 Speaker 1: your dreams. Mr Roney, congratulations and you're doing a good 589 00:36:06,600 --> 00:36:10,440 Speaker 1: job that since you're beautiful. So uh, if you want 590 00:36:10,440 --> 00:36:12,400 Speaker 1: to let us know about how you stuck it to 591 00:36:12,440 --> 00:36:16,080 Speaker 1: the man, you can tell us via Twitter at s 592 00:36:16,160 --> 00:36:19,120 Speaker 1: Y s K podcast on Facebook dot com slash stuff 593 00:36:19,120 --> 00:36:22,759 Speaker 1: you should know, uh, through email. It's stuff podcasts at 594 00:36:22,760 --> 00:36:25,640 Speaker 1: how stuff Works dot com and check out our website 595 00:36:25,640 --> 00:36:32,840 Speaker 1: while you're at it, Stuff you Should Know dot com 596 00:36:32,880 --> 00:36:35,319 Speaker 1: for more on this and thousands of other topics. Is 597 00:36:35,320 --> 00:36:43,760 Speaker 1: it how stuff works dot com.