1 00:00:00,240 --> 00:00:02,960 Speaker 1: Hey, everyone, We're coming to Salt Lake City, Utah, and Phoenix, 2 00:00:03,000 --> 00:00:06,840 Speaker 1: Arizona this fall. Yeah, October, we're gonna be at Salt 3 00:00:06,920 --> 00:00:09,959 Speaker 1: Lake Cities Grand Theater and then the next night October 4 00:00:10,600 --> 00:00:14,160 Speaker 1: will be in Phoenix. And we added a second show 5 00:00:14,240 --> 00:00:17,200 Speaker 1: to our Melbourne show, right, that's right, a second earlier 6 00:00:17,200 --> 00:00:19,840 Speaker 1: show in Melbourne. So you can get all the information 7 00:00:19,880 --> 00:00:22,200 Speaker 1: for all of these shows at s y s K 8 00:00:22,400 --> 00:00:27,319 Speaker 1: live dot com. Welcome to Stuff you Should Know from 9 00:00:27,360 --> 00:00:38,280 Speaker 1: how Stuff Works dot com. Hey, and welcome to the podcast. 10 00:00:38,400 --> 00:00:41,680 Speaker 1: I'm Josh Clark, There's Charles w Chuck Brie, there's Jerry 11 00:00:41,720 --> 00:00:45,160 Speaker 1: over there, and here we are doing maybe what's gonna 12 00:00:45,200 --> 00:00:47,400 Speaker 1: be the best episode of Stuff you Should Know We've 13 00:00:47,400 --> 00:00:52,479 Speaker 1: ever released? Jerry's back. Yeah, welcome back Jerry from hospice. 14 00:00:52,520 --> 00:00:56,640 Speaker 1: You said she just through her her can of carbonated 15 00:00:56,640 --> 00:01:01,040 Speaker 1: water down and belched. Is gonna name check it, But 16 00:01:01,320 --> 00:01:03,640 Speaker 1: I'm glad you didn't. Man, we do enough buzz marketing 17 00:01:03,640 --> 00:01:07,480 Speaker 1: as it is. Seriously, we can never do enough of that. 18 00:01:07,800 --> 00:01:13,440 Speaker 1: I agree. Um, So, how are you feeling? Okay? Yeah? 19 00:01:13,480 --> 00:01:16,000 Speaker 1: I feel like this article has ticked me off, though 20 00:01:16,160 --> 00:01:20,280 Speaker 1: it is it's not that that Freud and Rick who 21 00:01:20,600 --> 00:01:24,720 Speaker 1: is that? Yeah, the only PhD how Stuff Works. Ever, 22 00:01:25,480 --> 00:01:28,280 Speaker 1: it's it wasn't he didn't do anything wrong. Like the 23 00:01:28,360 --> 00:01:31,559 Speaker 1: logic behind the copy layout is what does it? It 24 00:01:31,600 --> 00:01:34,479 Speaker 1: is almost like designed to keep from sticking in your 25 00:01:34,520 --> 00:01:37,039 Speaker 1: mind to information you're reading. It's like, it's like if 26 00:01:37,080 --> 00:01:40,039 Speaker 1: a person who in a grocery store put the milk 27 00:01:40,280 --> 00:01:43,840 Speaker 1: together with like the canned spinach in an aisle and 28 00:01:43,959 --> 00:01:47,039 Speaker 1: expected people to be able to find it. All right, 29 00:01:47,040 --> 00:01:49,480 Speaker 1: all right, it's got worse than that. The cheese puffs 30 00:01:50,800 --> 00:01:55,400 Speaker 1: and the game, the cheese puffs and the cash shots. 31 00:01:57,480 --> 00:02:02,080 Speaker 1: Actually the little I can do this. Maybe by the 32 00:02:02,160 --> 00:02:04,080 Speaker 1: end of the episode, I'll have it. But the point is, 33 00:02:04,720 --> 00:02:09,200 Speaker 1: how about the oatmeal with a pickled herring? Okay, it's 34 00:02:09,240 --> 00:02:11,519 Speaker 1: funny that you, like, we're picking things are still in 35 00:02:11,560 --> 00:02:16,120 Speaker 1: the same unit. My imagination died at age ten. I 36 00:02:16,200 --> 00:02:20,240 Speaker 1: just thought I turned into a robot about that. I 37 00:02:20,280 --> 00:02:22,480 Speaker 1: thought it was a pretty dry article though, that was 38 00:02:22,560 --> 00:02:26,720 Speaker 1: like none of the character of How Stuff Works articles 39 00:02:26,720 --> 00:02:30,120 Speaker 1: that it read like a medical journal from the nineteen fifties, 40 00:02:30,360 --> 00:02:33,000 Speaker 1: a diabetes how to article. Yeah, I was like, boy, 41 00:02:33,440 --> 00:02:35,640 Speaker 1: how are we gonna make this fun? Well, that's our job. 42 00:02:35,840 --> 00:02:39,040 Speaker 1: I know. So let's get started making this fun. Huh. Yeah, 43 00:02:39,040 --> 00:02:45,440 Speaker 1: how about some stats, yeah, because these are pretty outdated. Uh, 44 00:02:45,800 --> 00:02:49,120 Speaker 1: it's gotten way worse since this article. It has, and 45 00:02:49,400 --> 00:02:51,400 Speaker 1: we're talking about in the United States, but in the 46 00:02:51,480 --> 00:02:55,800 Speaker 1: last twenty years, type two diabetes has tripled. Eight four 47 00:02:55,840 --> 00:03:01,280 Speaker 1: million Americans now have pre diabetes and don't know. Yeah, 48 00:03:01,639 --> 00:03:04,760 Speaker 1: that's startling. Yeah, we'll we'll get into pre diabetes in 49 00:03:04,800 --> 00:03:08,600 Speaker 1: a minute. And about thirty million people currently have diabetes 50 00:03:08,639 --> 00:03:13,160 Speaker 1: in America type two or total I think total at 51 00:03:13,160 --> 00:03:18,239 Speaker 1: a total cost of um, including lost wages, about three 52 00:03:18,280 --> 00:03:21,880 Speaker 1: hundred and twenty seven billion dollars a year a year. Yeah, 53 00:03:22,200 --> 00:03:25,320 Speaker 1: in the United States alone. I saw worldwide something like 54 00:03:25,400 --> 00:03:29,520 Speaker 1: four hundred million people have diabetes and America makes up 55 00:03:29,520 --> 00:03:34,200 Speaker 1: how many of those? Uh? Yeah, okay, which is surprising 56 00:03:34,240 --> 00:03:35,680 Speaker 1: because it didn't used to be that way. It used 57 00:03:35,680 --> 00:03:39,560 Speaker 1: to be like a wealthy Western disease, and all of 58 00:03:39,600 --> 00:03:43,680 Speaker 1: a sudden it's starting to spread throughout the world, which 59 00:03:43,760 --> 00:03:46,080 Speaker 1: is really kind of shocking and jarring. Like this is 60 00:03:46,120 --> 00:03:49,920 Speaker 1: a huge increase in this disease. It's become a really 61 00:03:50,120 --> 00:03:53,840 Speaker 1: big problem for not just like healthcare networks, but you know, 62 00:03:54,000 --> 00:03:57,000 Speaker 1: the people with diabetes too. They're dying from it something 63 00:03:57,040 --> 00:03:59,720 Speaker 1: like a million and a half deaths a year in 64 00:03:59,760 --> 00:04:02,200 Speaker 1: the world. Yeah, it's it's a seventh leading cause of 65 00:04:02,240 --> 00:04:04,640 Speaker 1: death in the the United States right now. And it's here's 66 00:04:04,680 --> 00:04:09,080 Speaker 1: the thing. It's the type two diabetes is, from what 67 00:04:09,120 --> 00:04:14,280 Speaker 1: we understand, utterly preventable. It looks like it is utterly 68 00:04:14,320 --> 00:04:17,279 Speaker 1: preventable from what from what I've seen. Not one single 69 00:04:17,360 --> 00:04:20,200 Speaker 1: person who has type two diabetes has to have it 70 00:04:20,240 --> 00:04:24,000 Speaker 1: like they were genetically destined to have it, although there 71 00:04:24,120 --> 00:04:27,640 Speaker 1: is some other evidence that we'll talk about that suggests otherwise. 72 00:04:27,680 --> 00:04:30,159 Speaker 1: But I don't want to give anything up. Yeah, but 73 00:04:30,240 --> 00:04:32,359 Speaker 1: I mean we can pretty much say now that it 74 00:04:32,480 --> 00:04:36,320 Speaker 1: is let's just go ahead and say largely caused by 75 00:04:37,000 --> 00:04:40,400 Speaker 1: being out of shape and being overweight and eating like 76 00:04:40,680 --> 00:04:45,320 Speaker 1: terrible stuff all the time. Yeah. I love this article, Chuck, 77 00:04:45,839 --> 00:04:49,200 Speaker 1: because it's one of those ones where it's like, oh, 78 00:04:49,279 --> 00:04:51,880 Speaker 1: all of this makes total sense. Like I love the 79 00:04:51,920 --> 00:04:55,920 Speaker 1: body just like I love Earth sciences. It's just we 80 00:04:55,960 --> 00:04:58,760 Speaker 1: can kind of it forms a system that we can understand, 81 00:04:58,800 --> 00:05:01,800 Speaker 1: and like when you understand this one part, you're like, oh, 82 00:05:01,800 --> 00:05:05,520 Speaker 1: this other part that happens makes total sense. That's diabetes. Yeah, 83 00:05:05,560 --> 00:05:08,000 Speaker 1: I hate the buddy in our sciences, I like um 84 00:05:08,200 --> 00:05:13,919 Speaker 1: mysticism and cosmology and dreadlocks. Oh boy, why do we 85 00:05:13,920 --> 00:05:16,000 Speaker 1: do that show on that? I was thinking of one 86 00:05:16,000 --> 00:05:18,960 Speaker 1: the other day that we did Jackammers. No, it's even 87 00:05:19,000 --> 00:05:21,680 Speaker 1: even worse than that. Oh I can't remember, but I 88 00:05:21,680 --> 00:05:25,919 Speaker 1: was like, why did we even attend that one? Occasionally 89 00:05:25,920 --> 00:05:27,480 Speaker 1: I'll look through the old list when we're picking out 90 00:05:27,480 --> 00:05:32,280 Speaker 1: selects and I should go, what to myself? It's weird? 91 00:05:33,120 --> 00:05:37,880 Speaker 1: All right? So we need to break down did mean 92 00:05:37,920 --> 00:05:41,640 Speaker 1: that pun? A lot of breaking down in this in 93 00:05:41,760 --> 00:05:44,520 Speaker 1: this show, you know what I mean? That was sort 94 00:05:44,520 --> 00:05:46,840 Speaker 1: of a deep that was a foreshadowing punt, how it was. 95 00:05:47,360 --> 00:05:50,000 Speaker 1: But we do need to break down the whole spiel 96 00:05:50,160 --> 00:05:54,520 Speaker 1: with glucose and insulin, because the root of at all 97 00:05:54,680 --> 00:05:59,440 Speaker 1: it's a disorder of glucose disorder. Yeah, it's a disorder 98 00:05:59,480 --> 00:06:02,000 Speaker 1: of both will yeah, either be fair either high or 99 00:06:02,000 --> 00:06:07,920 Speaker 1: low or none? Yeah. So okay, Well let's talk about 100 00:06:07,920 --> 00:06:11,080 Speaker 1: glucose first, all right, Well, before we even talk about glucose, 101 00:06:12,200 --> 00:06:15,320 Speaker 1: we need to define what a simple sugar is, or 102 00:06:15,400 --> 00:06:18,840 Speaker 1: a simple carbohydrate it can be called. These are carbs 103 00:06:18,880 --> 00:06:22,719 Speaker 1: that are absorbed very quickly for energy. And they're called 104 00:06:22,760 --> 00:06:24,680 Speaker 1: simple because they only have one or two units of 105 00:06:24,680 --> 00:06:29,039 Speaker 1: sugar as opposed to like a complex carbohydrate. And glucose 106 00:06:29,120 --> 00:06:32,400 Speaker 1: is a simple sugar, right, And since it's a simple sugar, 107 00:06:32,440 --> 00:06:34,080 Speaker 1: I think that means it can be broken down from 108 00:06:34,160 --> 00:06:37,839 Speaker 1: different types of complex sugars, So not just like sugar, 109 00:06:37,880 --> 00:06:40,479 Speaker 1: but carbs like you said, right, yeah, And this is 110 00:06:40,520 --> 00:06:42,760 Speaker 1: the sugar that gives all the cells in your body 111 00:06:42,920 --> 00:06:47,800 Speaker 1: energy to do sell selly things. Enters the bloodstream through 112 00:06:47,839 --> 00:06:50,839 Speaker 1: the intestine. All the cells are like, give me some sugar, baby, yeah. 113 00:06:51,160 --> 00:06:53,680 Speaker 1: And this comes from the foot food food that you eat. 114 00:06:53,880 --> 00:06:56,960 Speaker 1: It really does. Right. So you eat some food, particularly 115 00:06:57,000 --> 00:06:59,920 Speaker 1: say a carbohydrate rich food, and your guts start to 116 00:07:00,040 --> 00:07:04,080 Speaker 1: break it down and it breaks down ultimately to that glucose, 117 00:07:04,480 --> 00:07:07,200 Speaker 1: the simplest form of sugar that the body can use 118 00:07:07,240 --> 00:07:11,360 Speaker 1: for energy without being stripped down further, and it shoots 119 00:07:11,400 --> 00:07:14,320 Speaker 1: out through the blood stream and it's just a free 120 00:07:14,360 --> 00:07:18,840 Speaker 1: for all. Right. Cells, like you said, use this stuff, 121 00:07:19,120 --> 00:07:22,040 Speaker 1: and some cells in particular use nothing but glucoset, some 122 00:07:22,160 --> 00:07:24,680 Speaker 1: use glucost and like other stuff like a TP, which 123 00:07:24,680 --> 00:07:29,360 Speaker 1: of those red blood cells. Brain cells quite importantly use 124 00:07:29,440 --> 00:07:34,119 Speaker 1: nothing but glucose for energy, So glucose is extraordinarily important. Yeah, 125 00:07:34,160 --> 00:07:36,240 Speaker 1: and what your body wants to do. We always talk 126 00:07:36,280 --> 00:07:40,000 Speaker 1: about that homeostasis. There's another example that your body wants 127 00:07:40,040 --> 00:07:43,680 Speaker 1: to keep a constant glucose supply for your cells. We 128 00:07:43,720 --> 00:07:47,640 Speaker 1: don't want it to be super high or too low. Uh. 129 00:07:47,680 --> 00:07:50,400 Speaker 1: And it does this in a pretty interesting way. Otherwise, 130 00:07:50,760 --> 00:07:52,800 Speaker 1: when we like right after we eat, we'd be great. 131 00:07:53,240 --> 00:07:55,000 Speaker 1: And then if we didn't eat for a while or 132 00:07:55,080 --> 00:07:59,320 Speaker 1: went to sleep at night, potentially our organs shut if 133 00:07:59,320 --> 00:08:01,360 Speaker 1: we slip along. And because again this is the stuff 134 00:08:01,400 --> 00:08:03,920 Speaker 1: that fuels your cells. Your cells need fuel twenty four 135 00:08:03,920 --> 00:08:06,640 Speaker 1: hours a day. It doesn't care whether you're sleeping or not. Right, 136 00:08:06,680 --> 00:08:08,960 Speaker 1: that would solve everything. If your cells went to sleep, 137 00:08:09,360 --> 00:08:12,360 Speaker 1: it would when you slept, they just stop yapping for once. No, 138 00:08:12,520 --> 00:08:16,440 Speaker 1: they're always talk talk talk, which actually I guess it 139 00:08:16,520 --> 00:08:18,920 Speaker 1: is good because again, if your cell stopped working, then 140 00:08:18,960 --> 00:08:24,200 Speaker 1: you die. Right, Okay, So that's glucose energy That power 141 00:08:24,280 --> 00:08:27,600 Speaker 1: sells some cells exclusively, and your body wants to keep 142 00:08:27,640 --> 00:08:30,320 Speaker 1: an eye constant level. Yeah, and you get it through food, 143 00:08:30,400 --> 00:08:34,720 Speaker 1: which could conceivably spike your glucose. So when you eat 144 00:08:34,880 --> 00:08:37,760 Speaker 1: something and all of a sudden, you have a surplus 145 00:08:37,800 --> 00:08:42,880 Speaker 1: of glucose rather than that even keel homeostasis glucose in 146 00:08:42,920 --> 00:08:46,560 Speaker 1: your bloodstream. Uh. Your body has a way of dealing 147 00:08:46,600 --> 00:08:50,839 Speaker 1: with this, and it's called insulin. And insulin is one 148 00:08:50,880 --> 00:08:54,439 Speaker 1: of two chemicals that are made by the pancreatic islets. 149 00:08:55,640 --> 00:08:59,640 Speaker 1: I s l et islets, right, I don't know, did 150 00:08:59,679 --> 00:09:03,280 Speaker 1: you look it up. I think it's islets, like islands, 151 00:09:03,320 --> 00:09:05,920 Speaker 1: like it means like tiny islands. That's probably it. And 152 00:09:05,920 --> 00:09:08,200 Speaker 1: they're they're they're called tiny islands. That's what we're gonna 153 00:09:08,200 --> 00:09:10,160 Speaker 1: call them from now on because I don't want to 154 00:09:10,160 --> 00:09:12,640 Speaker 1: get it wrong for the rest of the episode. But 155 00:09:12,800 --> 00:09:16,760 Speaker 1: they're they're called tiny islands because they're indeed little endocrine 156 00:09:16,760 --> 00:09:21,160 Speaker 1: cells inside your pancreas, so they're they're embedded like a 157 00:09:21,240 --> 00:09:25,959 Speaker 1: journalist with a troop detachment. Basically. Yeah, so you're pancreas 158 00:09:26,120 --> 00:09:30,199 Speaker 1: in uh In in this case is producing to insulin 159 00:09:30,280 --> 00:09:35,680 Speaker 1: and glcagon I'm sorry, glucagon. Glucagon glucagon or alpha cells 160 00:09:35,920 --> 00:09:39,320 Speaker 1: produced by alpha cells and secreted by alpha cells. Insulin 161 00:09:39,520 --> 00:09:42,839 Speaker 1: are the beta cells. All of its produced in the pancreas. 162 00:09:42,920 --> 00:09:46,319 Speaker 1: Like you said, with those little islands. But so let's focus. 163 00:09:46,559 --> 00:09:50,079 Speaker 1: And here's a better one than than a military um 164 00:09:50,320 --> 00:09:55,040 Speaker 1: uh analogy a post office in an airport. It's like here, 165 00:09:55,040 --> 00:09:57,600 Speaker 1: we're gonna serve you, our customers. We're just gonna go 166 00:09:57,679 --> 00:10:00,719 Speaker 1: to you. Do they have those? Yes? Some do? Man. 167 00:10:00,840 --> 00:10:03,480 Speaker 1: I think there's one of the Toronto Airport. Yeah, there is, 168 00:10:04,360 --> 00:10:08,800 Speaker 1: y y z so um who thought that was gonna 169 00:10:08,880 --> 00:10:12,280 Speaker 1: come up? Huh. So you've got these little cells that 170 00:10:12,320 --> 00:10:15,480 Speaker 1: are specialized to create insulin, to release insulin from the 171 00:10:15,559 --> 00:10:18,600 Speaker 1: liver um, you know, from the pancrease, I'm sorry. In 172 00:10:18,880 --> 00:10:22,839 Speaker 1: response to glucost becoming abundant in your gut, as you're 173 00:10:22,840 --> 00:10:25,959 Speaker 1: digesting it, your gut sends out signals saying, hey, I 174 00:10:26,080 --> 00:10:27,719 Speaker 1: got a bunch of gluecoats here. You guys want to 175 00:10:27,760 --> 00:10:30,840 Speaker 1: do something, and the beta cells say we're on it 176 00:10:30,880 --> 00:10:34,120 Speaker 1: and start releasing insulin. So insulin enters the blood stream, 177 00:10:34,360 --> 00:10:37,720 Speaker 1: and its whole jam is to take the glucoast that 178 00:10:37,880 --> 00:10:41,960 Speaker 1: enters the blood stream and give it two cells and 179 00:10:42,000 --> 00:10:46,079 Speaker 1: it doesn't just push it down the cells throats. Apparently 180 00:10:46,120 --> 00:10:48,040 Speaker 1: the cells have some sort of say in whether they 181 00:10:48,040 --> 00:10:51,280 Speaker 1: accept gluecoast or not. But the only The only person 182 00:10:51,360 --> 00:10:54,440 Speaker 1: they're going to accept glucose from is insulin, So insulin 183 00:10:54,480 --> 00:10:57,760 Speaker 1: will take this gluecoast too. Different types of cells and 184 00:10:57,800 --> 00:11:01,720 Speaker 1: with different cells, Um, different things happened to it, right, Yeah, 185 00:11:01,880 --> 00:11:03,600 Speaker 1: Like it depends on what part of your body. If 186 00:11:04,000 --> 00:11:06,640 Speaker 1: you're the liver or muscle cells is going to store 187 00:11:06,640 --> 00:11:10,200 Speaker 1: that glucose and something called glycogen. Yeah, it's like just 188 00:11:10,320 --> 00:11:13,880 Speaker 1: chains of glucose, right. Yeah, it's gonna stimulate fat cells 189 00:11:13,920 --> 00:11:17,560 Speaker 1: to form fats from fatty acids and glycerol. Uh. Then 190 00:11:17,600 --> 00:11:19,600 Speaker 1: the liver and muscle cells is gonna make those make 191 00:11:19,640 --> 00:11:22,600 Speaker 1: proteins from amino acids. Yeah. And these are like the 192 00:11:22,640 --> 00:11:26,160 Speaker 1: three base proteins or based nutrients that you get from 193 00:11:26,200 --> 00:11:31,880 Speaker 1: eating food, right, amino acids, fats, fatty acids, and glucose. Correct. 194 00:11:32,040 --> 00:11:34,840 Speaker 1: And then your body makes use of those because insulin 195 00:11:34,880 --> 00:11:37,840 Speaker 1: deliverism two cells around the body. Yeah, then it's gonna 196 00:11:37,880 --> 00:11:41,839 Speaker 1: inhibit the liver and kidney cells from making glucose. Uh. 197 00:11:41,880 --> 00:11:45,240 Speaker 1: And this is something called gluco neo genesis, which is 198 00:11:45,920 --> 00:11:50,679 Speaker 1: confuse me just a little bit. Why, Yeah, because it 199 00:11:50,840 --> 00:11:53,920 Speaker 1: just I don't know something about the metabolic pathway, Like 200 00:11:54,520 --> 00:11:56,600 Speaker 1: I don't know I didn't fully grasp it. I think 201 00:11:56,600 --> 00:11:58,360 Speaker 1: what it is is that maybe my answer is just 202 00:11:58,440 --> 00:12:00,360 Speaker 1: I'm not smart enough to get I don't think that's 203 00:12:00,400 --> 00:12:06,000 Speaker 1: it at all. If if anything, yeah, that's your problem. Um. 204 00:12:06,040 --> 00:12:08,079 Speaker 1: If anything, it was the article Chuck not you. Well, 205 00:12:08,120 --> 00:12:10,599 Speaker 1: now this article is pretty stinky, but also went to 206 00:12:10,679 --> 00:12:13,080 Speaker 1: kids health sites like I always do. But it makes sense, 207 00:12:13,120 --> 00:12:16,000 Speaker 1: and that like if you will die, if you don't 208 00:12:16,000 --> 00:12:19,719 Speaker 1: have the source of of energy, you're gonna have some 209 00:12:19,840 --> 00:12:23,360 Speaker 1: backup plan. And the backup plan is, well, we probably 210 00:12:23,400 --> 00:12:25,880 Speaker 1: have some constituent parts that we can put together to 211 00:12:25,920 --> 00:12:28,400 Speaker 1: make our own glue cose. So that's like Plan B 212 00:12:29,440 --> 00:12:34,040 Speaker 1: is make your own glue cose. And that's Gluco Neo Genesis. Okay, 213 00:12:34,400 --> 00:12:37,480 Speaker 1: that's what I think. I mean, that's my interpretation. And 214 00:12:37,480 --> 00:12:41,640 Speaker 1: I play a doctor on TV. Dr Drake Remore. What's 215 00:12:41,679 --> 00:12:44,880 Speaker 1: U from those Friends? You probably didn't watch Friends? Did you? 216 00:12:45,080 --> 00:12:49,319 Speaker 1: I saw an episode or two. I love that. Were 217 00:12:49,320 --> 00:12:52,079 Speaker 1: you into Friends? Oh yeah I still am? Yeah, I'll 218 00:12:52,080 --> 00:12:55,680 Speaker 1: watch those reruns. Oh really? Yeah, it's funny. It's very 219 00:12:55,760 --> 00:13:00,120 Speaker 1: dated show now. Oh man, the clothes, the hairs, the 220 00:13:00,120 --> 00:13:03,840 Speaker 1: white people. Yeah, I mean everything about it that they 221 00:13:03,960 --> 00:13:06,200 Speaker 1: hung out at a coffee shop when that was new, 222 00:13:07,240 --> 00:13:09,280 Speaker 1: because if you cast that show today, it would look 223 00:13:09,280 --> 00:13:13,960 Speaker 1: like a Bennetton Colors ad. And rightly so, probably so. Alright, 224 00:13:14,040 --> 00:13:16,439 Speaker 1: So at the end of the day, though, insulin is 225 00:13:16,440 --> 00:13:19,160 Speaker 1: gonna store nutrients right after you eat that meal, but 226 00:13:19,360 --> 00:13:22,720 Speaker 1: by reducing these concentrations of glucose and like you said, 227 00:13:22,760 --> 00:13:26,839 Speaker 1: the fatty acids and amino acids, those three main components, right, 228 00:13:27,080 --> 00:13:29,240 Speaker 1: which is pretty interesting because you really only hear of 229 00:13:29,280 --> 00:13:31,840 Speaker 1: insulin dealing with blood sugar, but it deals with the 230 00:13:31,880 --> 00:13:35,160 Speaker 1: main three nutrients. I didn't know that before, did you. 231 00:13:36,080 --> 00:13:38,120 Speaker 1: I don't think I did. It's a it's a pretty 232 00:13:38,120 --> 00:13:40,400 Speaker 1: handy little hormone to have, and by the way, it's 233 00:13:40,400 --> 00:13:43,320 Speaker 1: a protein hormone. Glucos gets all the headlines it does 234 00:13:43,440 --> 00:13:46,040 Speaker 1: because it's the troublemaker. And we'll see what happens when 235 00:13:46,440 --> 00:13:49,679 Speaker 1: insulin can't do its job. What you get his diabetes 236 00:13:49,720 --> 00:13:52,160 Speaker 1: and the symptoms of diabetes. We'll talk about that later, 237 00:13:52,200 --> 00:13:55,560 Speaker 1: but first let's talk about glucagon. I thought you said 238 00:13:55,559 --> 00:13:59,440 Speaker 1: for a second, the Simpsons of diabetes. The symptoms, Yeah, 239 00:13:59,480 --> 00:14:03,439 Speaker 1: I know the Simpsons. No, the who would have diabetes 240 00:14:03,480 --> 00:14:06,520 Speaker 1: on the Simpsons? Oh? Probably Homer and Wigham, yeah, I 241 00:14:06,520 --> 00:14:11,640 Speaker 1: guess and Barney yeah, and well that will become clear 242 00:14:11,800 --> 00:14:15,160 Speaker 1: as we explain diabetes more. Right, But let's talk about 243 00:14:15,200 --> 00:14:18,360 Speaker 1: glucagon real quick, because you've got insulin doing its thing, 244 00:14:18,559 --> 00:14:21,600 Speaker 1: and it's pretty clear now what insulin does, but there's 245 00:14:21,640 --> 00:14:25,560 Speaker 1: another hormone that does the exact opposite that comes from 246 00:14:25,560 --> 00:14:28,960 Speaker 1: those pancreatic tiny islands too. Yeah, this I thought was 247 00:14:28,960 --> 00:14:31,400 Speaker 1: pretty neat as far as that homeostasis, that the body 248 00:14:31,400 --> 00:14:35,240 Speaker 1: has like two methods to deal with this, you know. Yep. 249 00:14:35,360 --> 00:14:38,560 Speaker 1: So like you said, if you go without eating or 250 00:14:38,760 --> 00:14:43,000 Speaker 1: you um sleep, if your cells don't get that glucose 251 00:14:43,080 --> 00:14:45,840 Speaker 1: that they need, they starve and die. So while you're 252 00:14:45,880 --> 00:14:48,880 Speaker 1: sleeping and not eating, your your cells are still powering. 253 00:14:48,920 --> 00:14:51,560 Speaker 1: They still need that energy. So your body has a 254 00:14:51,600 --> 00:14:54,720 Speaker 1: way to deal with this, and it is by producing 255 00:14:54,760 --> 00:14:59,360 Speaker 1: glucag glucogen, right, Yes, And it's a little confusing because 256 00:14:59,360 --> 00:15:03,600 Speaker 1: it's glucagon and glucogen. Oh yeah, I'm talking about both 257 00:15:03,600 --> 00:15:06,560 Speaker 1: with the G. Glucagon is what I'm talking about. That's 258 00:15:06,560 --> 00:15:10,240 Speaker 1: how your body deals with a lack of a flood 259 00:15:10,280 --> 00:15:14,120 Speaker 1: of new glucost being introduced from food, that's right, And 260 00:15:14,480 --> 00:15:17,200 Speaker 1: that comes from the alpha cells of the pancreatic islets, 261 00:15:17,280 --> 00:15:20,400 Speaker 1: right yeah, and it it acts on those same cells, 262 00:15:20,480 --> 00:15:23,400 Speaker 1: but it just has the opposite effect, which is pretty cool. 263 00:15:23,480 --> 00:15:26,400 Speaker 1: Like in the end, it's gonna like when you're sleeping 264 00:15:26,400 --> 00:15:30,080 Speaker 1: and when you're not eating, it's gonna mobilize glucose and 265 00:15:30,120 --> 00:15:31,920 Speaker 1: where it's stored up your body and say, hey, we 266 00:15:31,960 --> 00:15:34,280 Speaker 1: need this stuff now, right, So it goes to the 267 00:15:34,320 --> 00:15:37,840 Speaker 1: liver cell and the muscles and the muscles and says, hey, 268 00:15:37,880 --> 00:15:42,720 Speaker 1: you remember the the glucogen. Isn't that what the chain 269 00:15:42,720 --> 00:15:48,360 Speaker 1: of it's called, Yes, glycogen. So the the glucagon goes 270 00:15:48,400 --> 00:15:52,280 Speaker 1: to the liver cells and the muscle cells, right, and 271 00:15:52,360 --> 00:15:54,800 Speaker 1: it says, hey, you remember the chain of glucose that 272 00:15:54,840 --> 00:15:57,760 Speaker 1: you made the glycogen the other day, Well, we need it, 273 00:15:58,400 --> 00:16:00,440 Speaker 1: and so break it up and spit it out to 274 00:16:00,480 --> 00:16:02,640 Speaker 1: me and I'll just get it into the blood stream. 275 00:16:02,920 --> 00:16:05,920 Speaker 1: And it does that to the liver and muscle cells. Um. 276 00:16:05,960 --> 00:16:09,840 Speaker 1: It also tells the kidneys and liver It says, by 277 00:16:09,840 --> 00:16:11,760 Speaker 1: the way, liver, while I'm here, why don't you kick 278 00:16:11,800 --> 00:16:16,440 Speaker 1: off some gluco neo genesis to make some glucose. And 279 00:16:16,480 --> 00:16:18,720 Speaker 1: so all of a sudden, the low blood sugar in 280 00:16:18,720 --> 00:16:21,920 Speaker 1: your blood stream comes up to normal, and your cells 281 00:16:21,960 --> 00:16:26,440 Speaker 1: all say hooray, we're saved, and insulin gets a lifted 282 00:16:26,520 --> 00:16:29,880 Speaker 1: up on everybody's shoulders and all the cells carried around 283 00:16:29,920 --> 00:16:36,000 Speaker 1: for triumphant fist shaking um parade. Yeah, and it's pretty 284 00:16:36,040 --> 00:16:38,440 Speaker 1: great because this is all happening when you're sleeping. This 285 00:16:38,520 --> 00:16:42,720 Speaker 1: is right. So all this, this is how your your 286 00:16:42,760 --> 00:16:45,840 Speaker 1: body keeps homeostasis for your blood sugar in your blood stream, 287 00:16:46,160 --> 00:16:49,920 Speaker 1: your cells powered, if you're healthy. If this goes wrong, 288 00:16:51,280 --> 00:16:54,760 Speaker 1: well you'll find out all about that right after these messages. 289 00:17:15,520 --> 00:17:19,800 Speaker 1: So I don't think we mentioned that there is an 290 00:17:19,840 --> 00:17:23,119 Speaker 1: ideal level here, and that's about ninety milligrams per one 291 00:17:23,520 --> 00:17:29,760 Speaker 1: milds of blood for your blood glucose concentration or five millimolar. Yeah, 292 00:17:29,880 --> 00:17:32,879 Speaker 1: and they, uh, you know that you can get this tested. 293 00:17:32,920 --> 00:17:35,639 Speaker 1: They have little strips where you can poke yourself in 294 00:17:35,680 --> 00:17:38,240 Speaker 1: the finger and bleed on the strip. Yeah. So this 295 00:17:38,320 --> 00:17:42,159 Speaker 1: is apparently the most complex thing I've since the breathalyzer. 296 00:17:43,040 --> 00:17:49,000 Speaker 1: You glucose call tolerance test um with a I'm sorry, 297 00:17:49,040 --> 00:17:51,280 Speaker 1: I guess that's not it. It's a gluck glucose meter. 298 00:17:52,440 --> 00:17:56,439 Speaker 1: You prick yourself and bleed onto that little strip of paper, 299 00:17:56,520 --> 00:18:00,359 Speaker 1: like you were saying that the blood react with a 300 00:18:00,480 --> 00:18:03,679 Speaker 1: chemical or with an enzyme I'm sorry. On the strip 301 00:18:04,640 --> 00:18:09,800 Speaker 1: it's called glucose oxidase, and so that creates an entirely 302 00:18:09,880 --> 00:18:14,959 Speaker 1: new compound, gluconate, which combines with another chemical, and that 303 00:18:15,000 --> 00:18:18,640 Speaker 1: turns the strip blue. Right, And so you would think, okay, well, 304 00:18:18,680 --> 00:18:23,600 Speaker 1: if it's blue, it's um it's it's I'm diabetic or 305 00:18:23,720 --> 00:18:25,879 Speaker 1: I'm in trouble. If it's not blue, I'm fine. No, 306 00:18:26,680 --> 00:18:31,560 Speaker 1: what the what the diabetes testing apparatus, I think that's 307 00:18:31,560 --> 00:18:35,159 Speaker 1: what they're called. Does it analyzes the shade of blue 308 00:18:35,200 --> 00:18:40,240 Speaker 1: that that turned? That's that's complicated. That's that's maybe the 309 00:18:40,280 --> 00:18:44,760 Speaker 1: best blue. Really, sure, it's a good second. That's the 310 00:18:44,760 --> 00:18:48,520 Speaker 1: only two blues, right, But I thought that'd be pretty 311 00:18:48,520 --> 00:18:50,120 Speaker 1: cool if that's how I did do it. I I was like, oh, 312 00:18:50,160 --> 00:18:55,080 Speaker 1: this is Robin's like, that's navy, this is cerulean, cerulian, 313 00:18:55,119 --> 00:18:57,399 Speaker 1: you're in trouble. Well, that's not how they used to 314 00:18:57,440 --> 00:19:01,119 Speaker 1: test it though. In fact, the full name for diabetes 315 00:19:01,200 --> 00:19:04,480 Speaker 1: is diabetes, and militis M E L L I T 316 00:19:04,680 --> 00:19:07,800 Speaker 1: U S, and that literally means sweet urine, because in 317 00:19:07,840 --> 00:19:13,200 Speaker 1: ancient times the test involved the physician drinking your urine 318 00:19:13,240 --> 00:19:16,800 Speaker 1: and going taste sweet. You're in trouble. You're in trouble. 319 00:19:16,920 --> 00:19:19,919 Speaker 1: You're in trouble. So if you say that you have 320 00:19:20,119 --> 00:19:24,240 Speaker 1: that sweet diabetes militis, you're saying you've got that sweet 321 00:19:24,280 --> 00:19:28,200 Speaker 1: sweet urine. You know. I wrote a back in the 322 00:19:28,280 --> 00:19:32,080 Speaker 1: day when I was writing spec scripts when I lived 323 00:19:32,080 --> 00:19:34,680 Speaker 1: in l A. I wrote a seventies show script and 324 00:19:34,880 --> 00:19:37,280 Speaker 1: uh it was a Halloween episode where Eric pete his 325 00:19:37,400 --> 00:19:40,480 Speaker 1: pants at a haunted house and the title of the 326 00:19:40,520 --> 00:19:43,640 Speaker 1: episode was urine for a Treat. Oh that's great, man. 327 00:19:43,960 --> 00:19:45,800 Speaker 1: I thought that was enough. It was like, man, they're 328 00:19:45,800 --> 00:19:48,600 Speaker 1: going to see that. That's it. You gotta publish those. 329 00:19:48,720 --> 00:19:51,480 Speaker 1: I'm gonna be I should take that up, surely. I 330 00:19:51,480 --> 00:19:53,359 Speaker 1: mean I don't have like a digital copy. I'd have 331 00:19:53,400 --> 00:19:57,600 Speaker 1: to literally find the paper, take a how many pages 332 00:19:57,640 --> 00:20:00,720 Speaker 1: do you think? I think it was like twenty four 333 00:20:00,760 --> 00:20:05,520 Speaker 1: to thirty perfect, take a photo of each page. Why 334 00:20:05,560 --> 00:20:08,800 Speaker 1: they didn't like it? Posted on Instagram a page day 335 00:20:08,840 --> 00:20:11,280 Speaker 1: for a month. People will go crazy for it. They 336 00:20:11,320 --> 00:20:13,440 Speaker 1: would love that. That's probably one of the better things 337 00:20:13,440 --> 00:20:15,879 Speaker 1: I ever wrote. Oh, good out there like it was 338 00:20:15,920 --> 00:20:18,520 Speaker 1: a legit sevenies show episode. I'll ever tell you about 339 00:20:18,560 --> 00:20:23,240 Speaker 1: the Simpsons script I wrote not enough about. So remember 340 00:20:23,280 --> 00:20:25,639 Speaker 1: the one where it turns out that Principal Skinners actually 341 00:20:25,720 --> 00:20:28,960 Speaker 1: arm In Tanzarian. That's one of the great episodes. This 342 00:20:29,000 --> 00:20:31,440 Speaker 1: one is if you If you remember, you know that's 343 00:20:31,480 --> 00:20:34,880 Speaker 1: Matt Greening's most hated episode. I think he hated that episode, 344 00:20:35,280 --> 00:20:37,000 Speaker 1: that one. I didn't know that at the time because 345 00:20:37,080 --> 00:20:39,399 Speaker 1: I wrote this on spec to hoping that they'd notice 346 00:20:39,480 --> 00:20:42,680 Speaker 1: it um although I never sent it in UM. But 347 00:20:42,880 --> 00:20:46,640 Speaker 1: the at the end of that episode, they the judge 348 00:20:47,000 --> 00:20:49,879 Speaker 1: says that it's you. They're You're never allowed to speak 349 00:20:49,880 --> 00:20:53,440 Speaker 1: of this, punishable by death or something like that. So 350 00:20:53,800 --> 00:20:56,720 Speaker 1: my episode starts with one of Armor tans Arian's old 351 00:20:56,720 --> 00:20:59,760 Speaker 1: friends coming to Springfield to start his life, anew Ida, 352 00:20:59,840 --> 00:21:02,800 Speaker 1: and he sees Principal Skinner and says, hey, arm in 353 00:21:02,920 --> 00:21:05,280 Speaker 1: Armor Tansarian, And all of a sudden the police surround 354 00:21:05,400 --> 00:21:09,040 Speaker 1: him and he's taken away to jail and held UM 355 00:21:09,080 --> 00:21:12,000 Speaker 1: and it gets out he escapes, I think, gets out, 356 00:21:12,119 --> 00:21:15,040 Speaker 1: and then Clinton was president when I wrote this, Um, 357 00:21:15,080 --> 00:21:17,639 Speaker 1: he gets out. Somehow it gets to like Clinton that 358 00:21:17,760 --> 00:21:21,199 Speaker 1: this town is like holding people hostage basically unconstitutionally, and 359 00:21:21,200 --> 00:21:25,080 Speaker 1: so Springfield gets invaded and yours was eighty pages long. 360 00:21:25,680 --> 00:21:29,879 Speaker 1: Uh no, I think it was like appropriately Yeah, I 361 00:21:29,920 --> 00:21:33,679 Speaker 1: think so. Actually, I imagine a different life where uh 362 00:21:33,800 --> 00:21:36,040 Speaker 1: I wrote for the seventy show, that seventy show, when 363 00:21:36,040 --> 00:21:38,680 Speaker 1: you wrote for the Simpsons and we like eight lunch 364 00:21:38,760 --> 00:21:41,280 Speaker 1: together on the Fox slot. Can I that'd be pretty cool? 365 00:21:41,359 --> 00:21:44,399 Speaker 1: You know? Can I tell you something though, I would 366 00:21:44,560 --> 00:21:49,800 Speaker 1: I prefer this. Oh yeah, yes, I prefer what we do. 367 00:21:50,080 --> 00:21:53,679 Speaker 1: As someone who's never written for The Simpsons, I prefer this. 368 00:21:53,800 --> 00:21:56,439 Speaker 1: Hey man, I've been to the writer's room before. I 369 00:21:56,480 --> 00:21:58,800 Speaker 1: know what it looks like to chain him to the desk. 370 00:21:58,840 --> 00:22:01,119 Speaker 1: I like it. We get to we don't have to 371 00:22:01,119 --> 00:22:04,560 Speaker 1: live in l A. Yeah, I like l A. I've 372 00:22:04,600 --> 00:22:06,119 Speaker 1: noticed a lot of our friends from New York are 373 00:22:06,160 --> 00:22:07,879 Speaker 1: starting to move to l A. Have you noticed that 374 00:22:08,320 --> 00:22:12,280 Speaker 1: it's like a hemorrhaging? Al Right, should we get back 375 00:22:12,280 --> 00:22:15,040 Speaker 1: to diabetes, we should probably just edit all that out. No, 376 00:22:15,119 --> 00:22:17,960 Speaker 1: I think that's a nice tangent. Al Right, So in 377 00:22:18,000 --> 00:22:22,000 Speaker 1: the case of diabetes, like we said, um it is, uh, well, 378 00:22:22,000 --> 00:22:23,959 Speaker 1: we already said what it was, but there are three types, 379 00:22:24,440 --> 00:22:28,840 Speaker 1: type one, type two, and gestational diabetes. Type one is 380 00:22:29,320 --> 00:22:32,480 Speaker 1: by far the in the minority. It's um. It says 381 00:22:32,480 --> 00:22:34,719 Speaker 1: here five to timber cent. But I saw like kind 382 00:22:34,760 --> 00:22:37,800 Speaker 1: of a straight up five number for the number of 383 00:22:37,880 --> 00:22:41,720 Speaker 1: diabetes cases overall. Okay, um, But they say five to 384 00:22:41,760 --> 00:22:45,439 Speaker 1: tim percent in this article. Or it's called juvenile diabetes 385 00:22:45,560 --> 00:22:49,080 Speaker 1: or insulin dependent diabetes. Uh. And this is caused by 386 00:22:49,119 --> 00:22:53,720 Speaker 1: a lack of insulin, either not much insulin or sometimes 387 00:22:53,800 --> 00:22:56,080 Speaker 1: no insulin at all in their blood. And this is 388 00:22:56,680 --> 00:23:00,240 Speaker 1: this is clearly genetic, right, it says an also could 389 00:23:00,240 --> 00:23:04,399 Speaker 1: be environmental, but yeah, they think it's possible, possible that 390 00:23:04,480 --> 00:23:07,560 Speaker 1: it's caused by a virus. Exposure to a virus earlier 391 00:23:07,560 --> 00:23:11,560 Speaker 1: in childhood. Interesting that sets off an autoimmune reaction, and 392 00:23:11,600 --> 00:23:14,600 Speaker 1: so your immune system attacks your beta cells that produce 393 00:23:14,680 --> 00:23:19,480 Speaker 1: insulin and just destroys them, and so you don't produce insulin. 394 00:23:20,000 --> 00:23:23,360 Speaker 1: And it happens in your your younger years, maybe adolescence, 395 00:23:23,400 --> 00:23:26,440 Speaker 1: which is why it's called juvenile diabetes. And you when 396 00:23:26,480 --> 00:23:30,760 Speaker 1: you have type one or juvenile diabetes, you are you're 397 00:23:30,800 --> 00:23:33,040 Speaker 1: dealing with it for life. And we'll talk about, you know, 398 00:23:33,119 --> 00:23:36,840 Speaker 1: managing and treating diabetes. Um, but there's no cure for diabetes. 399 00:23:37,280 --> 00:23:40,119 Speaker 1: But the idea that it's possible that this is the 400 00:23:40,160 --> 00:23:42,480 Speaker 1: result of a virus has made some people call for 401 00:23:42,520 --> 00:23:47,280 Speaker 1: research into a type one diabetes vaccine. Interesting, which would 402 00:23:47,320 --> 00:23:51,879 Speaker 1: just change everything for some people. Yeah, because I mean, like, 403 00:23:51,920 --> 00:23:54,800 Speaker 1: I don't like it's certainly not like you get what 404 00:23:54,840 --> 00:23:57,080 Speaker 1: you deserve kind of thing with type two diabetes. But 405 00:23:57,119 --> 00:24:01,600 Speaker 1: type one diabetes. Man, you've got zero saying that's whatsoever. Yeah, 406 00:24:01,760 --> 00:24:05,080 Speaker 1: so type two is the one that's most prevalent between 407 00:24:06,760 --> 00:24:12,919 Speaker 1: adult onset diabetes. That is, when uh, you are usually 408 00:24:12,920 --> 00:24:16,760 Speaker 1: over forty um, usually between fifty and sixty. Even I'm 409 00:24:16,880 --> 00:24:19,840 Speaker 1: so nervous you were usually overweight. Why are you nervous. 410 00:24:19,960 --> 00:24:22,840 Speaker 1: I'm just nervous. I'man end up with type two diabetes. 411 00:24:22,840 --> 00:24:24,760 Speaker 1: By I thought you meant you were going to say 412 00:24:24,760 --> 00:24:29,600 Speaker 1: something wrong. No, I'm nervous. You're nervous about diabetes too. Yeah, 413 00:24:29,680 --> 00:24:33,240 Speaker 1: it sounds like it's virtually predestined that we're going to 414 00:24:33,280 --> 00:24:34,879 Speaker 1: get it. I don't think it's in my family. But 415 00:24:34,960 --> 00:24:38,359 Speaker 1: I'm overweight and forty seven years old, and like, you 416 00:24:38,480 --> 00:24:41,600 Speaker 1: need to get my act together, Like now, yes, you 417 00:24:41,640 --> 00:24:44,040 Speaker 1: know it's not like, yeah, I'll wait another five or 418 00:24:44,080 --> 00:24:46,160 Speaker 1: six years and then tackle it. And there's no reason 419 00:24:46,200 --> 00:24:48,120 Speaker 1: for us to like just put it off until the end. 420 00:24:48,160 --> 00:24:51,160 Speaker 1: We can say, like you can you can reverse pre 421 00:24:51,240 --> 00:24:54,800 Speaker 1: diabetes through diet and exercise. You don't. Even if you 422 00:24:54,840 --> 00:24:58,480 Speaker 1: have pre diabetes. You can, which is you have higher 423 00:24:58,480 --> 00:25:00,760 Speaker 1: than normal blood sugars. We'll see, but you don't have 424 00:25:00,800 --> 00:25:03,800 Speaker 1: full blown diabetes yet. You can actually reverse course, like 425 00:25:03,880 --> 00:25:06,320 Speaker 1: it's not too late doing something like what you're talking about, 426 00:25:07,119 --> 00:25:08,760 Speaker 1: and it's great. This is a wake up called like 427 00:25:08,800 --> 00:25:11,359 Speaker 1: your body literally can inch up to that line and 428 00:25:11,400 --> 00:25:13,160 Speaker 1: if you do the right thing, it can go whoa, 429 00:25:13,320 --> 00:25:16,000 Speaker 1: All right, yeah, I'll back off then. I like, I 430 00:25:16,040 --> 00:25:18,160 Speaker 1: like the way you're going here, Like what I'm saying, 431 00:25:18,160 --> 00:25:20,720 Speaker 1: give me some more less celery, baby, get on that peloton. 432 00:25:20,840 --> 00:25:25,200 Speaker 1: Chuck that that was a buzz market right there. Well 433 00:25:25,200 --> 00:25:28,840 Speaker 1: they're an advertiser with us, are they still? Well? They were, 434 00:25:28,880 --> 00:25:31,240 Speaker 1: and I still have that thing. I love it. It's nice. 435 00:25:31,440 --> 00:25:34,080 Speaker 1: I just need to love it every day, not like 436 00:25:34,320 --> 00:25:38,480 Speaker 1: I love it every couple of weeks. That hill, you know, anyway, 437 00:25:39,520 --> 00:25:43,000 Speaker 1: Type two, like I said, is about and this is 438 00:25:43,000 --> 00:25:47,119 Speaker 1: when you have higher insulin in your blood not lower 439 00:25:47,280 --> 00:25:50,440 Speaker 1: like in the case of type one, right, because you 440 00:25:50,880 --> 00:25:54,880 Speaker 1: have a lot of insulin. It's just not working, which 441 00:25:54,920 --> 00:25:58,919 Speaker 1: is why type two diabetes is also called insulin resistant diabetes. 442 00:25:59,000 --> 00:26:03,680 Speaker 1: Is that right on? Insulent dependent or insulent resistant? Yeah? Okay, yeah, 443 00:26:03,720 --> 00:26:06,480 Speaker 1: so that means that your body is producing insulin just fine, 444 00:26:07,040 --> 00:26:09,760 Speaker 1: but for some reason or another, and this seems to 445 00:26:09,800 --> 00:26:13,320 Speaker 1: be the mystery at the heart of diabetes. Your cells 446 00:26:13,400 --> 00:26:17,240 Speaker 1: don't respond to insulin anymore. They won't say, oh, it's insulin, sure, 447 00:26:17,240 --> 00:26:19,520 Speaker 1: bring me some glucosset, I'll turn it into a chain 448 00:26:19,600 --> 00:26:23,679 Speaker 1: of of glucose. They don't know exactly why, right, I mean, 449 00:26:24,240 --> 00:26:26,400 Speaker 1: that's what I'm saying. That's that's why it's the mystery 450 00:26:26,440 --> 00:26:28,679 Speaker 1: at the heart of diabetes. They don't know what the 451 00:26:28,720 --> 00:26:31,040 Speaker 1: problem is with insulin. If they could figure that out, 452 00:26:31,119 --> 00:26:34,080 Speaker 1: I think that they could actually cure diabetes. Instead, what 453 00:26:34,160 --> 00:26:37,760 Speaker 1: they've learned to to cure is some of the problems 454 00:26:37,760 --> 00:26:41,240 Speaker 1: associated with it, which is but they do definitely know 455 00:26:41,320 --> 00:26:45,520 Speaker 1: it's for sure linked to obesity, Yes they do. So 456 00:26:45,800 --> 00:26:47,920 Speaker 1: that's type two. We'll talk a little more about how 457 00:26:47,960 --> 00:26:50,600 Speaker 1: that actually works. As far as you know the the 458 00:26:50,640 --> 00:26:54,000 Speaker 1: effects that it has on your body. But one of 459 00:26:54,000 --> 00:26:57,440 Speaker 1: the some other research I found was that there's some 460 00:26:57,520 --> 00:27:02,080 Speaker 1: evidence that it's possible that type two diabetes, the actual 461 00:27:02,160 --> 00:27:06,199 Speaker 1: mechanism of it, is the result of folded, misfolded proteins. 462 00:27:06,640 --> 00:27:08,680 Speaker 1: So the same type of thing is like mad cow 463 00:27:08,800 --> 00:27:12,240 Speaker 1: disease or guru that you get from eating like brains 464 00:27:12,720 --> 00:27:15,639 Speaker 1: with some sort of sponge ofform disease. Right, remember that 465 00:27:15,760 --> 00:27:19,560 Speaker 1: we talked about that vaguely, So, um, they think that 466 00:27:19,600 --> 00:27:22,160 Speaker 1: it's possible that type two diabetes is the same thing 467 00:27:22,280 --> 00:27:27,320 Speaker 1: misfolded protein. And the third one it kind of relates 468 00:27:27,359 --> 00:27:31,040 Speaker 1: to type two diabetes. That seems as well, just stational diabetes. Yeah, 469 00:27:31,119 --> 00:27:34,360 Speaker 1: this is Uh. If you're a pregnant woman, you can 470 00:27:34,480 --> 00:27:39,520 Speaker 1: have or acquire I guess gestational diabetes. Um. The good 471 00:27:39,560 --> 00:27:44,000 Speaker 1: news that usually will go away after your baby is delivered. Um, 472 00:27:44,040 --> 00:27:46,000 Speaker 1: but it can put you at risk for type two 473 00:27:46,080 --> 00:27:49,040 Speaker 1: later on. You're more at risk if you're over twenty 474 00:27:49,040 --> 00:27:51,800 Speaker 1: five having a baby, if you have a baby over 475 00:27:52,520 --> 00:27:55,480 Speaker 1: or have had a baby over nine pounds. Oh yeah, 476 00:27:55,920 --> 00:27:59,159 Speaker 1: uh yeah, if you are overweight, if you have a 477 00:27:59,200 --> 00:28:02,440 Speaker 1: family history of it, or if you are African American, 478 00:28:03,160 --> 00:28:09,560 Speaker 1: Hispanic Latina, or Native American Native American Pacific islander, and 479 00:28:09,640 --> 00:28:13,520 Speaker 1: I believe that's it, okay, so um, which is interesting, 480 00:28:13,600 --> 00:28:17,040 Speaker 1: it really is. And I I didn't see anywhere why 481 00:28:17,080 --> 00:28:20,920 Speaker 1: they thought that, I think, really different different ethnicities, Yeah, 482 00:28:20,960 --> 00:28:23,280 Speaker 1: why they would be at a higher risk than I 483 00:28:23,359 --> 00:28:27,400 Speaker 1: don't know. So um, I think that I get the impression, Chuck, 484 00:28:27,600 --> 00:28:30,719 Speaker 1: that there's been like the American Diabetes Association has been 485 00:28:30,720 --> 00:28:32,360 Speaker 1: around for a while and all that stuff, and they've 486 00:28:32,359 --> 00:28:35,840 Speaker 1: been trying to do what they can. But then this 487 00:28:35,840 --> 00:28:41,280 Speaker 1: this enormous spike in diabetes cases in the West and 488 00:28:41,320 --> 00:28:44,320 Speaker 1: now the world has really kind of drawn attention and 489 00:28:44,360 --> 00:28:48,200 Speaker 1: funding to it, and we're now really diving in to 490 00:28:48,280 --> 00:28:50,760 Speaker 1: figure out what's going on. But we haven't figured it 491 00:28:50,760 --> 00:28:54,320 Speaker 1: out yet, which is where we are right now. I'm sorry. 492 00:28:54,320 --> 00:28:57,800 Speaker 1: One more thing, um, gestational diabetes they think can actually 493 00:28:57,960 --> 00:29:01,120 Speaker 1: be passed down as type two diabetes. These to the 494 00:29:01,280 --> 00:29:06,640 Speaker 1: offspring's interesting, that's yeah. Wow. Yeah, So we're just learning 495 00:29:06,680 --> 00:29:09,960 Speaker 1: about all this stuff now. Alright. So symptom wise for 496 00:29:10,080 --> 00:29:15,720 Speaker 1: all three versions and types of diabetes. Uh, Polly, Well, 497 00:29:15,760 --> 00:29:17,440 Speaker 1: why should I say that when I can just say 498 00:29:17,560 --> 00:29:22,080 Speaker 1: you're very thirsty, Polly dips you. You means you're very thirsty, 499 00:29:22,200 --> 00:29:26,480 Speaker 1: you urinate a lot, uh if you're always hungry. Uh if, 500 00:29:26,680 --> 00:29:30,680 Speaker 1: but you are also losing weight and you can't explain that. Yeah, 501 00:29:30,720 --> 00:29:33,080 Speaker 1: I didn't know that part about diabetes. But now that 502 00:29:33,120 --> 00:29:36,840 Speaker 1: I understand diabetes, that makes sense. Yeah, um, glucose in 503 00:29:36,840 --> 00:29:41,560 Speaker 1: the urine. That's sweet, sweet taste of urine. Uh. Fatigued 504 00:29:41,600 --> 00:29:46,680 Speaker 1: a lot, tired, blurred vision specifically like changes in your vision, um, 505 00:29:46,760 --> 00:29:51,480 Speaker 1: numb hands and feet, fingertips, slow healing wounds, and then 506 00:29:52,320 --> 00:29:56,200 Speaker 1: uh abnormally high frequency of infection. Right. So that's all 507 00:29:56,240 --> 00:29:59,160 Speaker 1: the Those are the symptoms, and they'll make sense once 508 00:29:59,200 --> 00:30:02,840 Speaker 1: we explain what's going on behind them, right. Yeah, but 509 00:30:02,960 --> 00:30:04,960 Speaker 1: in some of these symptoms though, in fact, a lot 510 00:30:04,960 --> 00:30:08,520 Speaker 1: of these symptoms can be other things too, which is 511 00:30:08,560 --> 00:30:11,760 Speaker 1: why it's sort of distressing to be doing research on 512 00:30:11,800 --> 00:30:14,400 Speaker 1: this and be like, well, wait a minute, my I 513 00:30:14,440 --> 00:30:17,760 Speaker 1: need glasses to read now. But that also and so 514 00:30:17,800 --> 00:30:21,360 Speaker 1: for forty, I'm tired a lot. That also happens when 515 00:30:21,360 --> 00:30:24,640 Speaker 1: you have a three year old. Um, I have a 516 00:30:24,680 --> 00:30:27,360 Speaker 1: lot of slow healing sores. No, I'm just kidding. My 517 00:30:27,400 --> 00:30:30,280 Speaker 1: phote was just amptutating because I had no sensation. I 518 00:30:30,320 --> 00:30:34,200 Speaker 1: do I get numbness in my hands and feet sometimes 519 00:30:34,200 --> 00:30:36,840 Speaker 1: when I sleep, but that's been happening since my early 520 00:30:36,880 --> 00:30:39,320 Speaker 1: thirties here and there, and that just could be because 521 00:30:39,320 --> 00:30:41,400 Speaker 1: you're you know, I sleep with my arm up and 522 00:30:41,440 --> 00:30:44,600 Speaker 1: stuff like that. So you know, I'm reading this stuff 523 00:30:44,600 --> 00:30:47,480 Speaker 1: and I'm freaking out. Go to the doctor. No I do. 524 00:30:47,640 --> 00:30:50,760 Speaker 1: And last time I went there, my blood sugar was fine. 525 00:30:51,280 --> 00:30:53,880 Speaker 1: I go every March. Oh, you're good, except I didn't 526 00:30:53,920 --> 00:30:56,200 Speaker 1: go this March. I didn't either. I've been going every 527 00:30:56,280 --> 00:30:58,560 Speaker 1: year and then skip this year, and now, um, we're 528 00:30:58,600 --> 00:31:00,840 Speaker 1: about to I think we just found a new doctor 529 00:31:00,920 --> 00:31:04,480 Speaker 1: who specializes in diabetes. I'm so nervous. I'm like, is 530 00:31:04,520 --> 00:31:07,400 Speaker 1: she is she one of those doctors who like is 531 00:31:07,440 --> 00:31:09,560 Speaker 1: like a hammer, so everything looks like a nail. Just 532 00:31:09,560 --> 00:31:11,720 Speaker 1: gonna be like, you have diabetes. I'm gonna trick myself 533 00:31:11,720 --> 00:31:14,320 Speaker 1: into actually thinking it. Yeah. I did the dumb thing 534 00:31:14,360 --> 00:31:17,440 Speaker 1: this year, which was, oh geez, I gain weight last year, 535 00:31:17,560 --> 00:31:19,560 Speaker 1: Like I'm gonna take your off and get back in 536 00:31:19,560 --> 00:31:22,240 Speaker 1: shape like that. I can't this, which is the opposite 537 00:31:22,560 --> 00:31:24,480 Speaker 1: of what you should do. But I was like, I 538 00:31:24,520 --> 00:31:26,120 Speaker 1: can't face my doctor because when I go in there, 539 00:31:26,160 --> 00:31:28,520 Speaker 1: he's like what are you doing, dude. He's very just 540 00:31:28,560 --> 00:31:30,560 Speaker 1: a matter of fact about everything. It's like, what are 541 00:31:30,560 --> 00:31:32,960 Speaker 1: you doing? You want to be one of those old 542 00:31:33,000 --> 00:31:36,680 Speaker 1: guys with diabetes R laying around. He'll say that stuff 543 00:31:36,680 --> 00:31:38,640 Speaker 1: to me. I know. He's like, good, well, you know 544 00:31:38,680 --> 00:31:40,760 Speaker 1: it's up to you. It's good to hear that. Yeah, 545 00:31:40,840 --> 00:31:42,480 Speaker 1: I mean, you need that kind of straight talk from 546 00:31:42,480 --> 00:31:46,120 Speaker 1: a doctor. You know, they say or I've read that. Um. 547 00:31:46,400 --> 00:31:49,160 Speaker 1: Weighing yourself every week if you're if you're trying to 548 00:31:49,600 --> 00:31:53,080 Speaker 1: lose weight, it's bad, No, it's good, or I should 549 00:31:53,120 --> 00:31:58,320 Speaker 1: say I've seen some you shouldn't it's too much. Yes. 550 00:31:58,800 --> 00:32:02,640 Speaker 1: Because your weight fluctual so randomly throughout the week, you 551 00:32:02,680 --> 00:32:05,320 Speaker 1: can get demoralized. You want to do it once a 552 00:32:05,360 --> 00:32:07,600 Speaker 1: week at the same time, usually right after you get 553 00:32:07,680 --> 00:32:11,760 Speaker 1: up the same morning every week, and then you will 554 00:32:11,800 --> 00:32:13,880 Speaker 1: see whether you're going up or down. You'll really be 555 00:32:13,920 --> 00:32:15,880 Speaker 1: able to see four times a week, you're just like 556 00:32:15,920 --> 00:32:17,640 Speaker 1: all over the place. It doesn't make any sense. You 557 00:32:18,480 --> 00:32:20,520 Speaker 1: can't make heads or tails of it. Once a week 558 00:32:20,560 --> 00:32:23,600 Speaker 1: at the same time that makes sense, and it has 559 00:32:23,640 --> 00:32:26,800 Speaker 1: the psychological effect of being like, well, I don't want 560 00:32:26,800 --> 00:32:28,560 Speaker 1: to I don't want to see it go up. So 561 00:32:28,680 --> 00:32:31,880 Speaker 1: I'm gonna, I'm gonna, I'm not gonna. I'm not gonna 562 00:32:31,880 --> 00:32:33,840 Speaker 1: eat that chocolate cigar. Now you have to step on 563 00:32:33,880 --> 00:32:35,760 Speaker 1: the scale. Oh yeah, yeah, Like I said, I weigh 564 00:32:35,800 --> 00:32:37,760 Speaker 1: myself too much, but I'll kick it down to once 565 00:32:37,760 --> 00:32:40,400 Speaker 1: a week. All right, let me know you, thank you, 566 00:32:40,840 --> 00:32:42,880 Speaker 1: thanks for doing that. Oh should we take a break? 567 00:32:44,160 --> 00:32:47,640 Speaker 1: Is it is this episode still going on? All right? Then? Yes, 568 00:32:47,680 --> 00:33:10,280 Speaker 1: all right, we'll be right back. All right, chuck. Yeah, 569 00:33:10,320 --> 00:33:13,240 Speaker 1: Now we get to the point of the article that's 570 00:33:13,280 --> 00:33:16,040 Speaker 1: called let's try and confuse people as much as possible. 571 00:33:16,120 --> 00:33:18,959 Speaker 1: This is where the grocery store starts putting weird stuff 572 00:33:18,960 --> 00:33:21,240 Speaker 1: next to other stuff and expect you to just pretend 573 00:33:21,240 --> 00:33:24,320 Speaker 1: like everything's normal. I tried to just mark the relevant 574 00:33:24,360 --> 00:33:27,040 Speaker 1: parts to make it all makes sense and streamline it, 575 00:33:27,640 --> 00:33:32,400 Speaker 1: and it still was confusing. Great, everybody, I just cracked 576 00:33:32,400 --> 00:33:34,840 Speaker 1: my knuckles. That means it's you just turned to chare 577 00:33:34,840 --> 00:33:41,280 Speaker 1: around backwards. Prepare, Prepare for the monotony. Ready the monotonous droning. Right, 578 00:33:41,320 --> 00:33:44,080 Speaker 1: which is basically, how does this out as a lack 579 00:33:44,120 --> 00:33:51,120 Speaker 1: of insulin affect your body? By Josh Clark. Yes, so, well, 580 00:33:51,200 --> 00:33:55,280 Speaker 1: let's take different ones. Right, you've got um blood. Well, 581 00:33:55,400 --> 00:33:58,560 Speaker 1: see here's here's a good example. You've got glucose appearing 582 00:33:58,560 --> 00:34:04,680 Speaker 1: in your urine above urinating frequently, but logically glucose appearing 583 00:34:04,720 --> 00:34:06,760 Speaker 1: in your urine should follow after it and be in 584 00:34:06,800 --> 00:34:09,640 Speaker 1: the same thing. So we're gonna start with your urinate frequently. 585 00:34:09,840 --> 00:34:13,279 Speaker 1: Poly dipsy I think is what, or no, poly syria 586 00:34:13,800 --> 00:34:18,120 Speaker 1: is what. It's called polyuria. So that just means you 587 00:34:18,200 --> 00:34:20,759 Speaker 1: pee a lot, way more than you normally would if 588 00:34:20,800 --> 00:34:24,120 Speaker 1: you didn't have diabetes. And this is actually easily explained. Right, 589 00:34:24,520 --> 00:34:28,200 Speaker 1: You've got a lot of glucose in your kidneys because 590 00:34:28,239 --> 00:34:31,000 Speaker 1: it's in your bloodstream and your kidneys are you're the filter, 591 00:34:31,400 --> 00:34:35,120 Speaker 1: one of the main filters for your body. Um, and 592 00:34:35,200 --> 00:34:39,560 Speaker 1: so when you have liquid waste, it goes to the kidneys, 593 00:34:39,640 --> 00:34:42,440 Speaker 1: and in that liquid waste is a lot more glucose 594 00:34:42,480 --> 00:34:45,399 Speaker 1: than your kiddies are used to processing, and so they 595 00:34:45,440 --> 00:34:49,840 Speaker 1: become overloaded. There's like a backup of glucos right, pretty simple, 596 00:34:49,920 --> 00:34:54,560 Speaker 1: easy peasy, um. So since there's a backup of this stuff, um, 597 00:34:54,640 --> 00:34:58,640 Speaker 1: the actual the actual thing that shoots urine off to 598 00:34:58,760 --> 00:35:06,080 Speaker 1: your your ethra, right, the tubule illumin it becomes backed 599 00:35:06,160 --> 00:35:09,799 Speaker 1: up with glucost as well. Yeah, because glucose retains water, right, 600 00:35:09,880 --> 00:35:12,600 Speaker 1: which means the tubule alumin says, well, I should probably 601 00:35:12,680 --> 00:35:14,720 Speaker 1: get rid of some of this and I'm gonna start peeing. 602 00:35:15,000 --> 00:35:18,160 Speaker 1: So you start peeing more and more, right, Okay, that's 603 00:35:18,239 --> 00:35:20,480 Speaker 1: one effect of it, and that will also help make 604 00:35:20,520 --> 00:35:22,759 Speaker 1: you thirsty, which is another symptom. That's another. It's like 605 00:35:22,800 --> 00:35:25,239 Speaker 1: a vicious cycle. Right. So you start drinking more, and 606 00:35:25,280 --> 00:35:27,719 Speaker 1: that is another symptom. So you're drinking more, but you're 607 00:35:27,760 --> 00:35:30,879 Speaker 1: just peeing more because there's so much glucose in your blood. Now, 608 00:35:30,880 --> 00:35:33,360 Speaker 1: because there's more glucost in your blood and you're peeing 609 00:35:33,360 --> 00:35:36,880 Speaker 1: out more water from your blood stream than usual, your 610 00:35:36,880 --> 00:35:39,600 Speaker 1: blood actually becomes a little thicker, yes, and you're also 611 00:35:39,640 --> 00:35:42,680 Speaker 1: losing sodium. Okay, right, so you're peeing a lot more. 612 00:35:42,719 --> 00:35:44,480 Speaker 1: You're drinking a lot more, but you're just peeing it 613 00:35:44,600 --> 00:35:48,000 Speaker 1: right out. Your blood is becoming thicker, So your body says, whoa, whoa, 614 00:35:48,040 --> 00:35:51,360 Speaker 1: something's a little off. I need some water and becoming dehydrated, 615 00:35:51,719 --> 00:35:54,800 Speaker 1: sending out this thirst signal isn't working. I'm gonna steal 616 00:35:54,880 --> 00:35:57,959 Speaker 1: some water from the organs, right, do they actually become 617 00:35:58,000 --> 00:36:00,959 Speaker 1: a little dehydrated. But the them as it doesn't solve 618 00:36:01,000 --> 00:36:04,240 Speaker 1: the problem because there's still all that glucose overloading your kidneys. 619 00:36:04,400 --> 00:36:07,480 Speaker 1: You just pee that water out, so again you're constantly thirsty. 620 00:36:07,719 --> 00:36:10,200 Speaker 1: There's a glucose that appears in your PA, which is 621 00:36:10,200 --> 00:36:13,600 Speaker 1: how ancient doctors um said, Yeah, you've got the diabetes 622 00:36:14,160 --> 00:36:18,040 Speaker 1: and you um, your your organs already hydrated, which is 623 00:36:18,040 --> 00:36:20,799 Speaker 1: a bad jam. Yeah, and I think they liken the 624 00:36:20,800 --> 00:36:24,320 Speaker 1: thick and blood to like a molasses consistency, right, not good. 625 00:36:24,640 --> 00:36:26,719 Speaker 1: This article isn't touch on it, but that leads to 626 00:36:26,760 --> 00:36:31,279 Speaker 1: another thing that's usually or often comorbid with diabetes is 627 00:36:31,360 --> 00:36:35,759 Speaker 1: hypertension high blood pressure because you're your your heart is 628 00:36:35,800 --> 00:36:38,320 Speaker 1: requiring more energy to pump this blood because it's thicker, 629 00:36:38,600 --> 00:36:41,000 Speaker 1: and it's actually really hard on your blood cells as well, 630 00:36:41,120 --> 00:36:42,799 Speaker 1: and that can lead to all sorts of things from 631 00:36:42,840 --> 00:36:46,040 Speaker 1: cardiac arrest a stroke. So you can get all those 632 00:36:46,120 --> 00:36:49,240 Speaker 1: in addition to diabetes just from having thick sweet blood. 633 00:36:49,960 --> 00:36:53,680 Speaker 1: Molasses blood dick and sweet is usually good, but not 634 00:36:53,800 --> 00:36:57,600 Speaker 1: in this case. Maybe if it's in the syrup that 635 00:36:57,640 --> 00:37:00,759 Speaker 1: you're eating that will eventually give you diabetes, it's good 636 00:37:02,760 --> 00:37:04,560 Speaker 1: h All right, now where does that put us? We're 637 00:37:04,560 --> 00:37:06,440 Speaker 1: going back up to the top. Yeah, we should, we 638 00:37:06,440 --> 00:37:11,080 Speaker 1: should participate in confusing people along with this article. Right. So, 639 00:37:11,520 --> 00:37:15,520 Speaker 1: the whole reason you have high blood glucose levels UM 640 00:37:15,680 --> 00:37:19,319 Speaker 1: is because your body is not responding to insulin, right, right, 641 00:37:20,040 --> 00:37:23,840 Speaker 1: So because the insulin is running around going guys, guys, 642 00:37:24,120 --> 00:37:26,760 Speaker 1: what what I do? What's the problem? Take this glucose 643 00:37:26,840 --> 00:37:29,080 Speaker 1: and the cells just turned their back on the insulin, 644 00:37:29,440 --> 00:37:33,000 Speaker 1: and the insulince is sad. You'll have a lot of 645 00:37:33,000 --> 00:37:36,359 Speaker 1: insulin in your blood stream, it's not doing anything, and 646 00:37:36,400 --> 00:37:40,240 Speaker 1: so there's some other secondary alarms that your body sets 647 00:37:40,239 --> 00:37:42,400 Speaker 1: off saying we've got a lot of we got a 648 00:37:42,480 --> 00:37:45,720 Speaker 1: lot of insulin in the blood stream, but our cells 649 00:37:45,760 --> 00:37:48,880 Speaker 1: aren't getting any energy. They're starving, so we need to 650 00:37:48,880 --> 00:37:53,359 Speaker 1: start producing our own glucose. Right, And that's where the glucagon. 651 00:37:54,960 --> 00:37:58,799 Speaker 1: The alpha cell secrete that glucagon and those levels rise 652 00:37:58,800 --> 00:38:01,360 Speaker 1: in your blood stream. That acts on your liver and 653 00:38:01,440 --> 00:38:04,560 Speaker 1: muscles like we talked about, to break down that glycogen 654 00:38:05,480 --> 00:38:09,040 Speaker 1: uh and releases well too much glucose into the blood 655 00:38:09,080 --> 00:38:11,520 Speaker 1: in that case, right, which is one reason why you 656 00:38:11,560 --> 00:38:16,400 Speaker 1: suddenly lose weight inexplicably despite eating all the time or 657 00:38:16,440 --> 00:38:18,799 Speaker 1: being hungry all the time, because as far as your 658 00:38:18,840 --> 00:38:22,200 Speaker 1: body is concerned, it's it's all it's pretend like your 659 00:38:22,200 --> 00:38:25,960 Speaker 1: body can't tell that there's a problem with the insulin. 660 00:38:26,080 --> 00:38:29,920 Speaker 1: All it knows is that the cells are starving. It's 661 00:38:30,120 --> 00:38:34,920 Speaker 1: it's like it's lacks some sort of uma to show 662 00:38:35,320 --> 00:38:38,680 Speaker 1: how much um, how much blood sugar there actually is 663 00:38:38,760 --> 00:38:42,319 Speaker 1: in the blood stream, or how much insulin there is, 664 00:38:42,520 --> 00:38:44,600 Speaker 1: and that there's something wrong. It just knows the cells 665 00:38:44,600 --> 00:38:47,200 Speaker 1: are starving, so it kicks off this thing where it 666 00:38:47,239 --> 00:38:50,200 Speaker 1: makes its own glucose, which just raises the levels even 667 00:38:50,200 --> 00:38:54,680 Speaker 1: further and exacerbates the problem. Right, Okay, so you're constantly 668 00:38:54,760 --> 00:38:57,239 Speaker 1: hungry because your body thinks your cells are starving, but 669 00:38:57,320 --> 00:38:59,920 Speaker 1: you start to lose weight despite eating, because it's also 670 00:39:00,040 --> 00:39:05,479 Speaker 1: attacking those stores of um glycogen, those glucose chains, and 671 00:39:05,920 --> 00:39:08,839 Speaker 1: you're just you start losing weight despite eating a lot. Yeah, 672 00:39:08,920 --> 00:39:11,200 Speaker 1: you're tired. That was another one of the symptoms because 673 00:39:11,800 --> 00:39:14,880 Speaker 1: you're not absorbing that glucose, so it's not doesn't have 674 00:39:14,920 --> 00:39:17,960 Speaker 1: anything to burn for energy. Your hands and feet, remember 675 00:39:18,080 --> 00:39:21,680 Speaker 1: I talked about them feeling numb or cold, that's because 676 00:39:21,719 --> 00:39:25,560 Speaker 1: it increases osmotic pressure of your blood, draws the water 677 00:39:25,600 --> 00:39:30,080 Speaker 1: from your tissues. That means your cells becomes everything becomes dehydrated. 678 00:39:30,520 --> 00:39:34,279 Speaker 1: And again that goes back to the kidneys. Uh, the 679 00:39:34,600 --> 00:39:36,879 Speaker 1: water in the blood is lost as urine because you're 680 00:39:36,880 --> 00:39:41,440 Speaker 1: being so much, you're literally pissing it away. Yeah, seriously, 681 00:39:41,520 --> 00:39:45,040 Speaker 1: And that basically that's what makes that blood thicker, which 682 00:39:45,120 --> 00:39:48,840 Speaker 1: leads to poor circulation. It's all. It sounds confusing, but 683 00:39:48,880 --> 00:39:50,919 Speaker 1: it all kind of makes sense in a cyclical way. 684 00:39:51,080 --> 00:39:54,080 Speaker 1: And so the poor circulation leads to its own cascade 685 00:39:54,080 --> 00:39:56,839 Speaker 1: of problems. Right, poor circulation means that you have less 686 00:39:56,880 --> 00:40:00,480 Speaker 1: feeling and sensation in your extremities, which means that if 687 00:40:00,520 --> 00:40:02,840 Speaker 1: you stub your toe or cut it open or something 688 00:40:02,920 --> 00:40:05,680 Speaker 1: like that, you might not even notice. So you have 689 00:40:05,800 --> 00:40:09,319 Speaker 1: a wound that's left of fester because you're not treating it. 690 00:40:09,600 --> 00:40:11,920 Speaker 1: And then and then on top of that, because of 691 00:40:11,920 --> 00:40:14,920 Speaker 1: the poor circulation, your immune system can't go to the 692 00:40:15,000 --> 00:40:18,759 Speaker 1: site and help it as easily, and you're more prone 693 00:40:18,800 --> 00:40:21,839 Speaker 1: to infections, which can lead to gang green, which can 694 00:40:21,840 --> 00:40:24,919 Speaker 1: actually lead to amputation. All because your blood is too 695 00:40:24,920 --> 00:40:28,560 Speaker 1: thick to circulate properly. Right, and that poor circulation is 696 00:40:28,600 --> 00:40:30,400 Speaker 1: also what's going to lead to your changes in vision 697 00:40:30,400 --> 00:40:34,000 Speaker 1: as well. Right, So there's one other thing that happens 698 00:40:34,040 --> 00:40:38,040 Speaker 1: to there's something called keto acidosis, which is where your 699 00:40:38,440 --> 00:40:41,520 Speaker 1: your metabolism basically goes into the fatty acids or the 700 00:40:41,560 --> 00:40:44,720 Speaker 1: fat cells and crack them open and starts burning whatever 701 00:40:44,760 --> 00:40:49,719 Speaker 1: glucose it can. Um. There's there's this thing called ketosis 702 00:40:49,719 --> 00:40:54,080 Speaker 1: where if you're on like a right where you it's 703 00:40:54,080 --> 00:40:56,359 Speaker 1: actually as far as that cans people are concerned, that's 704 00:40:56,400 --> 00:40:59,120 Speaker 1: like where you want to be because you're just burning 705 00:40:59,360 --> 00:41:04,160 Speaker 1: fat cell and you're at this buzzing level. Um, and 706 00:41:04,239 --> 00:41:07,160 Speaker 1: you're you're losing weight, you're not gaining anything you can. 707 00:41:07,320 --> 00:41:11,279 Speaker 1: Your skull is very prominent, it's a beautiful thing. Right. 708 00:41:11,520 --> 00:41:14,120 Speaker 1: Your breath is kind of stinky. Yeah, it'll seem a 709 00:41:14,160 --> 00:41:19,440 Speaker 1: little sweet. Keto Acidosis is not keytosis. Keyto acidosis is um. 710 00:41:19,480 --> 00:41:22,360 Speaker 1: It's it's the same thing but to the nth degree. 711 00:41:22,800 --> 00:41:25,480 Speaker 1: And it can lead to all sorts of big problems 712 00:41:25,480 --> 00:41:31,000 Speaker 1: because the the the acidic keytones build up in your liver. 713 00:41:31,160 --> 00:41:33,239 Speaker 1: I think that can cause stinky breath too, right, it 714 00:41:33,320 --> 00:41:36,360 Speaker 1: can acetone breath, Yeah, and it's that can lead to 715 00:41:36,400 --> 00:41:40,520 Speaker 1: central nervous system problems, heart trouble, and even it can 716 00:41:40,640 --> 00:41:44,120 Speaker 1: lead to coma, yeah, and hard irregularities too. It can 717 00:41:44,160 --> 00:41:46,120 Speaker 1: mess your body at pretty bad. And this can be 718 00:41:46,560 --> 00:41:49,759 Speaker 1: an extreme result of diabetes, which is one of the 719 00:41:50,040 --> 00:41:54,560 Speaker 1: reasons it's life threatening. Man, it's a big deal. It 720 00:41:54,760 --> 00:41:58,160 Speaker 1: is so as far as monitoring this stuff. Back in 721 00:41:58,200 --> 00:42:01,319 Speaker 1: the day, you just had to monitor it every day, 722 00:42:01,320 --> 00:42:03,759 Speaker 1: and some people still do that with the little pin 723 00:42:03,800 --> 00:42:06,960 Speaker 1: prick and uh, they're glucose monitors. But now you can 724 00:42:06,960 --> 00:42:09,960 Speaker 1: add have them, Uh, you can have them built into 725 00:42:09,960 --> 00:42:13,239 Speaker 1: your body. Right. Oh, that's actually that's been around a 726 00:42:13,239 --> 00:42:16,160 Speaker 1: little while. So if you're type one, you have to 727 00:42:16,600 --> 00:42:18,759 Speaker 1: you don't make insulin, so you have to inject it 728 00:42:18,840 --> 00:42:23,040 Speaker 1: artificially from externally. And there's like pumps that you can 729 00:42:23,160 --> 00:42:26,000 Speaker 1: carry around your ware that are connected into your body 730 00:42:26,040 --> 00:42:29,560 Speaker 1: that you just press a button and it um it 731 00:42:29,640 --> 00:42:31,960 Speaker 1: delivers insuline. But you have to test to see how 732 00:42:32,040 --> 00:42:35,279 Speaker 1: much you need at any given time, right, and if 733 00:42:35,280 --> 00:42:37,840 Speaker 1: you if you put in too much insulin, it's gonna 734 00:42:37,880 --> 00:42:41,680 Speaker 1: sweep up too much blood sugar. Because there's it's not 735 00:42:41,719 --> 00:42:45,160 Speaker 1: like there's anything wrong with the communication between your insulin 736 00:42:45,200 --> 00:42:47,520 Speaker 1: and your cells. With type one diabetes, it's just that 737 00:42:47,600 --> 00:42:50,120 Speaker 1: you don't have insuline. So when you put insulin in 738 00:42:50,160 --> 00:42:52,680 Speaker 1: your body, it does, it goes to work like it's 739 00:42:52,719 --> 00:42:55,600 Speaker 1: supposed to. So you have to really walk that fine 740 00:42:55,640 --> 00:42:58,320 Speaker 1: line well and you probably are going to be administering 741 00:42:58,320 --> 00:43:00,680 Speaker 1: it a few times a day to right, and so 742 00:43:00,680 --> 00:43:03,839 Speaker 1: you've ausually around your meals and you want to make 743 00:43:03,880 --> 00:43:05,799 Speaker 1: sure that you don't again put in too much or 744 00:43:05,800 --> 00:43:08,480 Speaker 1: else you're gonna get lightheaded because your brain cells use 745 00:43:08,520 --> 00:43:10,880 Speaker 1: glucoast and if you have too much insulin stopping up 746 00:43:10,920 --> 00:43:14,719 Speaker 1: too much glucose, your brain starves and you pass out. Yeah, 747 00:43:14,760 --> 00:43:19,880 Speaker 1: it's called hypoglycemia. Uh, like you said, lightheaded, shaky um. 748 00:43:19,920 --> 00:43:23,759 Speaker 1: I think most people have experienced that feeling, even if 749 00:43:23,800 --> 00:43:28,000 Speaker 1: you don't have like pre diabetes or diabetes. Just that. 750 00:43:28,320 --> 00:43:31,160 Speaker 1: I mean, people just call it low blood sugar, right, 751 00:43:31,160 --> 00:43:33,879 Speaker 1: but it's actually probably and yeah, I guess it would 752 00:43:33,920 --> 00:43:36,919 Speaker 1: be low blood sugar from an over abundance of insulin. Yeah. 753 00:43:36,960 --> 00:43:38,680 Speaker 1: The only time I've noticed that is when I eat 754 00:43:39,120 --> 00:43:45,200 Speaker 1: uh something super carbi like, and I don't really do 755 00:43:45,239 --> 00:43:47,040 Speaker 1: that for I don't need a lot of breakfast anyway. 756 00:43:47,040 --> 00:43:50,160 Speaker 1: But if I eat just like like a big fat 757 00:43:50,200 --> 00:43:53,520 Speaker 1: bagel for breakfast and then don't eat again till dinner, 758 00:43:54,000 --> 00:43:56,719 Speaker 1: I'll get like a little shaky, yeah, the shakes. Yeah, 759 00:43:56,760 --> 00:43:59,680 Speaker 1: but it almost feels good in a weird way, you 760 00:43:59,719 --> 00:44:02,359 Speaker 1: know what talking about? Not to me, No, it's never 761 00:44:02,400 --> 00:44:05,920 Speaker 1: felt like kind of high, like you're a little high. 762 00:44:06,520 --> 00:44:08,359 Speaker 1: Every once in a while, not every time, but every 763 00:44:08,360 --> 00:44:10,240 Speaker 1: once a while will strike me where I'm like shaky, 764 00:44:10,280 --> 00:44:13,960 Speaker 1: But right here in my chest, in my solar plexus, 765 00:44:14,000 --> 00:44:15,960 Speaker 1: I can kind of feel it glowing a little bit, 766 00:44:16,000 --> 00:44:19,640 Speaker 1: and it's almost it's almost like a weird high. Interesting. Yeah, 767 00:44:19,880 --> 00:44:22,640 Speaker 1: and I is that that's not a normal thing. I mean, 768 00:44:22,760 --> 00:44:26,120 Speaker 1: I can only speak for myself. I do know that though, 769 00:44:26,160 --> 00:44:30,040 Speaker 1: if you are feeling lightheaded or shaky like that, because 770 00:44:30,120 --> 00:44:32,360 Speaker 1: this is because your brain is not getting enough glucose. 771 00:44:32,719 --> 00:44:34,239 Speaker 1: And we talked about the brain was one of the 772 00:44:34,320 --> 00:44:38,160 Speaker 1: specific organs that really needs it. Um. This is when 773 00:44:38,200 --> 00:44:40,760 Speaker 1: you might see someone drink juice or eat a candy 774 00:44:40,760 --> 00:44:44,040 Speaker 1: bar or something sweet just to get that like quick spike. 775 00:44:44,800 --> 00:44:46,440 Speaker 1: But if it goes really really low, you can go 776 00:44:46,440 --> 00:44:50,160 Speaker 1: into what's called uh insulin shock, where you lapse into 777 00:44:50,239 --> 00:44:55,640 Speaker 1: a coma and that's serious business. Oh yeah, a diabetic 778 00:44:55,680 --> 00:44:59,000 Speaker 1: coma is pretty bad because all sorts of bad stuff 779 00:44:59,040 --> 00:45:02,879 Speaker 1: can happen to your brain at that time. So that's, um, 780 00:45:02,960 --> 00:45:06,840 Speaker 1: that's mostly type one. Type two is managed differently, although 781 00:45:06,880 --> 00:45:09,160 Speaker 1: similarly you have to keep up with your blood sugar 782 00:45:09,520 --> 00:45:11,879 Speaker 1: not nearly as frequently as you do with type one, 783 00:45:12,040 --> 00:45:14,880 Speaker 1: but diet and exercise or like they just say right away, 784 00:45:15,000 --> 00:45:20,479 Speaker 1: like if even if you well, let's talk a little 785 00:45:20,480 --> 00:45:24,080 Speaker 1: bit about reversibility, because I saw a new study. Okay, well, 786 00:45:24,120 --> 00:45:26,839 Speaker 1: let's hear it. Here's a new study that's called very 787 00:45:26,880 --> 00:45:29,080 Speaker 1: low calory diet in six months of wait stability and 788 00:45:29,120 --> 00:45:32,240 Speaker 1: Type two diabetes. And this was on the American Diabetes 789 00:45:32,280 --> 00:45:36,719 Speaker 1: Association homepage. Uh, and they did a study basically because 790 00:45:36,719 --> 00:45:39,319 Speaker 1: it's long been thought that even though they say, like 791 00:45:39,360 --> 00:45:43,239 Speaker 1: you know, if you really lose weight and exercise, it 792 00:45:43,280 --> 00:45:47,279 Speaker 1: will really really help you manage your diabetes. But it's 793 00:45:47,280 --> 00:45:50,600 Speaker 1: not reversible, like you've got it for life. You have 794 00:45:50,680 --> 00:45:53,880 Speaker 1: to if you stopped exercising and dieting, you would exactly 795 00:45:53,960 --> 00:45:58,400 Speaker 1: develop the symptoms again, right exactly. But they now say, 796 00:45:58,880 --> 00:46:02,279 Speaker 1: um that it is possible with at least for the 797 00:46:02,320 --> 00:46:04,680 Speaker 1: results of the study. And here's the deal. It wasn't 798 00:46:04,680 --> 00:46:07,400 Speaker 1: a very robust study. It was only thirty people with 799 00:46:07,440 --> 00:46:12,479 Speaker 1: type two diabetes. UM, I think it was they didn't 800 00:46:12,520 --> 00:46:16,560 Speaker 1: have a good enough sample of ethnicities. But some of 801 00:46:16,560 --> 00:46:19,960 Speaker 1: the subject had diabetes less than four years, some had 802 00:46:20,040 --> 00:46:23,200 Speaker 1: longer than eight years. Uh. And they found that and 803 00:46:23,560 --> 00:46:27,239 Speaker 1: this is usually after a very bariatric surgery. But they 804 00:46:27,280 --> 00:46:29,400 Speaker 1: did find the same results of people who just and 805 00:46:29,440 --> 00:46:33,080 Speaker 1: this is dramatic calorie reduction, not just like, well, I'm 806 00:46:33,080 --> 00:46:38,880 Speaker 1: gonna eat a little better like bariatric surgery level calorie reduction. Uh. 807 00:46:38,920 --> 00:46:43,000 Speaker 1: They found that immediately after an eight week low calorie, 808 00:46:43,120 --> 00:46:46,920 Speaker 1: very low calorie diet, twelve of the thirty participants had 809 00:46:47,160 --> 00:46:52,880 Speaker 1: fasting blood glucose levels normal fasting blood glucose levels. And 810 00:46:52,920 --> 00:46:55,640 Speaker 1: then and this is the big finding, after six months 811 00:46:55,680 --> 00:46:58,960 Speaker 1: of maintenance, thirteen out of the thirty, we're able to 812 00:46:59,040 --> 00:47:02,440 Speaker 1: keep that glucose level below that threshold. That means that 813 00:47:04,560 --> 00:47:08,719 Speaker 1: we're seemingly reversible. But they're not making the claim like 814 00:47:08,800 --> 00:47:12,640 Speaker 1: for sure, but thirty people that yeah, I mean that's 815 00:47:12,640 --> 00:47:16,640 Speaker 1: promising that the people that really really lost a lot 816 00:47:16,640 --> 00:47:19,400 Speaker 1: of weight and ate a lot less. An exercise were 817 00:47:19,400 --> 00:47:21,960 Speaker 1: able to seemingly reverse or at least get it down 818 00:47:22,000 --> 00:47:24,520 Speaker 1: to normal. But like you said, if they stopped then 819 00:47:24,560 --> 00:47:27,480 Speaker 1: it it might just come right back. And that fasting 820 00:47:27,800 --> 00:47:31,000 Speaker 1: glucose level is is significant. I don't think we really said, 821 00:47:31,040 --> 00:47:33,720 Speaker 1: but the fast One of the ways that they test 822 00:47:33,840 --> 00:47:37,040 Speaker 1: for for diabetes is, Yeah, you fast overnight, go to 823 00:47:37,120 --> 00:47:40,320 Speaker 1: your doctor and they give you a thing of sugar 824 00:47:40,320 --> 00:47:43,080 Speaker 1: water and you drink it, and then they start testing 825 00:47:43,080 --> 00:47:46,759 Speaker 1: your blood sugar for several hours afterward. And if you 826 00:47:46,840 --> 00:47:50,960 Speaker 1: don't have diabetes, your blood sugar comparatively speaking, doesn't spike 827 00:47:51,000 --> 00:47:54,799 Speaker 1: all that much because your insolence working and doing the 828 00:47:54,880 --> 00:47:57,000 Speaker 1: right thing. So if you have full blown type two 829 00:47:57,000 --> 00:48:01,080 Speaker 1: diabetes and you're in the study and you go take 830 00:48:01,120 --> 00:48:05,640 Speaker 1: a diabetes test and you have regular fasting level diabetes 831 00:48:05,920 --> 00:48:08,960 Speaker 1: blood sugar, yeah, that's pretty significant for sure. Yeah. I 832 00:48:09,000 --> 00:48:12,800 Speaker 1: hope it extract plates onto everybody else. Well, we'll see. Um, 833 00:48:12,840 --> 00:48:17,080 Speaker 1: it's normally controlled through medication oral medication for type two. 834 00:48:17,680 --> 00:48:19,160 Speaker 1: It's not like you're having to give yourself a shot 835 00:48:19,160 --> 00:48:22,719 Speaker 1: every few hours or anything. Um. Yeah, that's that's big. 836 00:48:22,760 --> 00:48:25,120 Speaker 1: There's and there's different ways to to do it. Yeah, 837 00:48:25,239 --> 00:48:27,840 Speaker 1: one one medication and I guess they just tailor it 838 00:48:27,920 --> 00:48:32,920 Speaker 1: to what your specific case might they think it might warrantably. 839 00:48:33,160 --> 00:48:36,360 Speaker 1: But one stimulates the pain crease to release more insulin. 840 00:48:36,760 --> 00:48:39,520 Speaker 1: That's kind of a no brainer. One interferes with the 841 00:48:39,560 --> 00:48:43,120 Speaker 1: absorption of glucose by the intestine. One interferes with the 842 00:48:43,160 --> 00:48:47,480 Speaker 1: absorption of glucose by the intestine. Ones improves insulin sensitivity. 843 00:48:48,000 --> 00:48:53,520 Speaker 1: One reduces glucose production by the liver, stops gluco neogenesis. Yeah, 844 00:48:53,560 --> 00:48:58,000 Speaker 1: one helps a breakdown um of glucose, and the other 845 00:48:58,000 --> 00:49:01,960 Speaker 1: one some literally supplement insulin, which makes me curious, like, 846 00:49:02,040 --> 00:49:05,120 Speaker 1: does that mean that if you if you inject more 847 00:49:05,200 --> 00:49:08,680 Speaker 1: insulin and type two diabetes, you overwhelm the insulin resistance 848 00:49:08,800 --> 00:49:12,879 Speaker 1: or something like that. I don't either, but if you so, 849 00:49:13,120 --> 00:49:16,759 Speaker 1: management is the right word for diabetes, Like you have 850 00:49:16,800 --> 00:49:19,040 Speaker 1: to pay attention to your diet, your exercise, You have 851 00:49:19,120 --> 00:49:22,279 Speaker 1: to test your blood sugar levels depending on what kind 852 00:49:22,320 --> 00:49:25,200 Speaker 1: you have day to day. But there are like a 853 00:49:25,200 --> 00:49:27,879 Speaker 1: lot of apps out there um to help you do that. 854 00:49:28,200 --> 00:49:30,560 Speaker 1: And since we're buzz marketing, you me works with a 855 00:49:30,560 --> 00:49:33,040 Speaker 1: guy or worked with a guy who's the CEO of 856 00:49:33,239 --> 00:49:36,680 Speaker 1: company called Gluco g l O g L O O 857 00:49:36,880 --> 00:49:39,719 Speaker 1: K O, and um, they're one of many. I mean, 858 00:49:39,719 --> 00:49:42,480 Speaker 1: there's a bunch of them. But if you have diabetes, 859 00:49:42,800 --> 00:49:46,239 Speaker 1: this is probably the most convenient time for you to 860 00:49:46,320 --> 00:49:48,800 Speaker 1: keep track of your diabetes because apparently it's a pain 861 00:49:49,239 --> 00:49:52,400 Speaker 1: too to keep up with the tests and all of 862 00:49:52,440 --> 00:49:56,439 Speaker 1: the stuff, the data and so chuck. There's like we said, 863 00:49:56,560 --> 00:50:01,000 Speaker 1: right now, there's apparently it's possible maybe to reverse it. 864 00:50:01,160 --> 00:50:05,160 Speaker 1: But for type one diabetes in particular, because remember you're 865 00:50:05,239 --> 00:50:10,160 Speaker 1: just not producing insulin. They've actually come up with a 866 00:50:10,239 --> 00:50:15,239 Speaker 1: procedure and experimental procedure called pancreatic islet transplantation. Yeah. I 867 00:50:15,239 --> 00:50:17,640 Speaker 1: saw that this has been around since like the sixties, 868 00:50:18,360 --> 00:50:21,040 Speaker 1: but um, like it's not new, but I couldn't really 869 00:50:21,040 --> 00:50:24,640 Speaker 1: find out if it's like the affectiveness of it now 870 00:50:24,760 --> 00:50:28,960 Speaker 1: and like if it's working, Um, is it working? That's 871 00:50:29,000 --> 00:50:31,320 Speaker 1: not good. If there was nothing, if you there was 872 00:50:31,360 --> 00:50:34,239 Speaker 1: no follow ups on it, that's I don't know. It 873 00:50:34,320 --> 00:50:37,080 Speaker 1: says that showed promise, but the big problem was tissue 874 00:50:37,120 --> 00:50:41,920 Speaker 1: rejection where it's so basically they go into a deceased 875 00:50:41,960 --> 00:50:45,960 Speaker 1: donor and they remove their pancreatic islets because remember that's 876 00:50:45,960 --> 00:50:50,919 Speaker 1: where the insulin and the UH glucagon is produced. Yeah, 877 00:50:50,960 --> 00:50:52,839 Speaker 1: that's like the root of the problem. And you put 878 00:50:52,880 --> 00:50:56,680 Speaker 1: it into a like a syringe in a catheter and 879 00:50:56,800 --> 00:51:01,440 Speaker 1: injected into the person with type one diabetes pancreas, and 880 00:51:01,480 --> 00:51:04,360 Speaker 1: supposedly they'll they'll eventually attached to a blood vessel and 881 00:51:04,400 --> 00:51:08,279 Speaker 1: start producing insulin. But if it that's if your your 882 00:51:08,360 --> 00:51:11,680 Speaker 1: the body doesn't reject the door tissue. Yeah, I'm gonna 883 00:51:11,680 --> 00:51:13,719 Speaker 1: follow up on that because I couldn't find a whole 884 00:51:13,719 --> 00:51:16,080 Speaker 1: lot about it and time ran short on me. But 885 00:51:16,480 --> 00:51:19,960 Speaker 1: I do know that that's I mean, it's been around 886 00:51:20,040 --> 00:51:23,399 Speaker 1: legitimately for at least three decades, and then before that 887 00:51:23,480 --> 00:51:26,320 Speaker 1: with like experimentation, so I don't know. It seems like 888 00:51:26,400 --> 00:51:30,000 Speaker 1: they would have had a firmer grasp on the results 889 00:51:30,040 --> 00:51:33,279 Speaker 1: by that, That's what I'm saying it. It's a little like, uh, yeah, 890 00:51:33,480 --> 00:51:38,959 Speaker 1: you know, we'll find out. Gluco. Have you got anything else? 891 00:51:39,640 --> 00:51:42,839 Speaker 1: Gluco the app? Yeah, yeah, go get it. It's pretty cool. 892 00:51:43,040 --> 00:51:46,560 Speaker 1: I checked it out. What did it say? It said 893 00:51:47,120 --> 00:51:50,120 Speaker 1: check me out? No, It's like, I don't have diabetes, 894 00:51:50,160 --> 00:51:51,880 Speaker 1: so a lot of it doesn't make sense to me. 895 00:51:51,920 --> 00:51:56,200 Speaker 1: But from the demonstration video, it seemed pretty robust. Yes, 896 00:51:56,680 --> 00:51:59,640 Speaker 1: and then some Um. If you want to know more 897 00:51:59,680 --> 00:52:05,440 Speaker 1: about diabetes, go check out this painfully confusing article on 898 00:52:05,440 --> 00:52:08,399 Speaker 1: how stuff works by typing that word in And since 899 00:52:08,440 --> 00:52:13,160 Speaker 1: I said painfully confusing, it's time for a listener man. Hey, 900 00:52:13,160 --> 00:52:14,960 Speaker 1: guys want to share some thoughts and comments on the 901 00:52:15,000 --> 00:52:17,560 Speaker 1: Skyscraper podcast. So we got a lot of feedback. We 902 00:52:17,680 --> 00:52:23,640 Speaker 1: got what do we get wrong? Steel? Yeah? Who cares? 903 00:52:24,840 --> 00:52:27,799 Speaker 1: It's not like we were telling people who were going 904 00:52:27,880 --> 00:52:30,960 Speaker 1: to go purify iron and then try to build a 905 00:52:31,000 --> 00:52:33,440 Speaker 1: skyscraper out of it. I mean for the number of 906 00:52:33,440 --> 00:52:35,319 Speaker 1: things that we say, of course we're going to get 907 00:52:35,360 --> 00:52:38,480 Speaker 1: something like dead wrong once in a while. Well, this 908 00:52:38,520 --> 00:52:45,279 Speaker 1: guy was nice about it, uh, and we asked for corrections. Uh. 909 00:52:45,400 --> 00:52:48,480 Speaker 1: Thank you. Guys did a great job, Josh of summarizing 910 00:52:48,520 --> 00:52:51,200 Speaker 1: the issue with the thicker bass I E pyramid not 911 00:52:51,239 --> 00:52:54,720 Speaker 1: being economical for the building owner for recuperating their initial investment. 912 00:52:54,760 --> 00:52:57,239 Speaker 1: You also did a good job bringing up that elevators 913 00:52:57,239 --> 00:53:01,000 Speaker 1: coincided allowed the jump and building height technology would allow 914 00:53:01,040 --> 00:53:02,840 Speaker 1: us to build nearly as tall as you want. You 915 00:53:02,840 --> 00:53:04,480 Speaker 1: just shouldn't be able to find someone willing to pay 916 00:53:04,520 --> 00:53:08,799 Speaker 1: for it. The difference, however, between iron and steel is 917 00:53:08,800 --> 00:53:11,680 Speaker 1: in fact not that steel is more pure iron. It 918 00:53:11,800 --> 00:53:16,320 Speaker 1: is iron with carbon added that increases UH and improves 919 00:53:16,719 --> 00:53:23,880 Speaker 1: the strength and ductility of pure and or naturally found iron. 920 00:53:24,320 --> 00:53:27,040 Speaker 1: Different steels have other elements added in addition to carbon, 921 00:53:27,360 --> 00:53:29,600 Speaker 1: but really carbon and iron are what makes steel steel. 922 00:53:30,080 --> 00:53:32,719 Speaker 1: Other elements have relatively minor impact on the properties, like 923 00:53:32,760 --> 00:53:38,040 Speaker 1: stainless steel has chromium, etcetera. Uh. There are also multiple 924 00:53:38,040 --> 00:53:41,040 Speaker 1: types of footings, not just spread footings. Spread footing spread 925 00:53:41,040 --> 00:53:44,200 Speaker 1: the load on underlying soil or ideally rocked because like 926 00:53:44,239 --> 00:53:46,759 Speaker 1: you said, the columns going straight into the soil would 927 00:53:46,760 --> 00:53:49,640 Speaker 1: push right through. But most, if not all, skyde scrapers 928 00:53:49,719 --> 00:53:52,120 Speaker 1: are so heavy it's it's so far above the rock. 929 00:53:52,440 --> 00:53:55,919 Speaker 1: Then instead of spread footings, they have a deep foundation. UH. 930 00:53:55,960 --> 00:53:58,120 Speaker 1: This looks very similar to a spread footing from the 931 00:53:58,160 --> 00:54:01,520 Speaker 1: bottom of the concrete footing up, but then also have 932 00:54:01,640 --> 00:54:03,759 Speaker 1: columns that reach further into the ground to increase the 933 00:54:03,840 --> 00:54:07,960 Speaker 1: resistance to the sinking. This resistance usually is provided by 934 00:54:07,960 --> 00:54:11,160 Speaker 1: those columns reaching down to very strong rock. Essentially, you're 935 00:54:11,200 --> 00:54:14,200 Speaker 1: creating a large table with lots of legs that the 936 00:54:14,200 --> 00:54:17,080 Speaker 1: whole building is built upon. That as an analogy I 937 00:54:17,080 --> 00:54:19,719 Speaker 1: can get down with. There you go, so look forward 938 00:54:19,719 --> 00:54:22,880 Speaker 1: to coming to another Atlanta show. This is Grant Hollis, 939 00:54:22,920 --> 00:54:25,279 Speaker 1: who lives right here. Thanks Grant, and he went to 940 00:54:25,320 --> 00:54:29,279 Speaker 1: the Pinto show. Grant Hollis man of Steel. That's right, 941 00:54:29,320 --> 00:54:31,920 Speaker 1: and Grant, I would normally just put you on the 942 00:54:31,920 --> 00:54:34,839 Speaker 1: guest list for tickets, but Atlanta is always tight because 943 00:54:34,840 --> 00:54:36,719 Speaker 1: their friends and family, So I'm sorry, we have to 944 00:54:36,760 --> 00:54:40,520 Speaker 1: like claw them from the promoter's hand. Yeah, and we 945 00:54:40,600 --> 00:54:43,400 Speaker 1: have to deny friends and family. Yeah, and they're cheap 946 00:54:43,440 --> 00:54:45,200 Speaker 1: so they don't buy tickets. They're like all right if 947 00:54:45,200 --> 00:54:49,400 Speaker 1: I I'm just not coming pretty much. Uh well, thanks again, Grant, 948 00:54:49,480 --> 00:54:51,600 Speaker 1: and thank you to our friends and family who show 949 00:54:51,680 --> 00:54:54,080 Speaker 1: up or even consider. Shall we go to right Lands shows. 950 00:54:54,600 --> 00:54:57,239 Speaker 1: If you want to get in touch with us, visit 951 00:54:57,280 --> 00:54:58,879 Speaker 1: us at our home on the web, Stuff you should 952 00:54:58,920 --> 00:55:01,279 Speaker 1: know dot com. He you can find our social all 953 00:55:01,320 --> 00:55:03,799 Speaker 1: over the place there, and you can also send us 954 00:55:03,840 --> 00:55:06,960 Speaker 1: an email to Stuff podcast at how Stuff Work. Stuff 955 00:55:11,920 --> 00:55:14,600 Speaker 1: for more on this and thousands of other topics. How 956 00:55:15,239 --> 00:55:21,320 Speaker 1: dot Com