1 00:00:01,160 --> 00:00:04,120 Speaker 1: Welcome to steph you missed in history class from how 2 00:00:04,160 --> 00:00:13,280 Speaker 1: Stuff Works dot Com. Hello, and welcome to the podcast. 3 00:00:13,360 --> 00:00:17,240 Speaker 1: I'm Holly Fry and I'm Tracy V. Wilson. So, like 4 00:00:17,400 --> 00:00:20,720 Speaker 1: months and months ago, like the beginning of our colleague 5 00:00:20,800 --> 00:00:23,880 Speaker 1: Julie put a book on my desk titled Catching Breath 6 00:00:24,160 --> 00:00:26,880 Speaker 1: and Making an Unmaking of Tuberculosis, and I was so 7 00:00:26,960 --> 00:00:29,800 Speaker 1: excited about it that it became comical in the office. 8 00:00:30,320 --> 00:00:32,600 Speaker 1: I think my actual immediate reaction was, we have to 9 00:00:32,640 --> 00:00:35,040 Speaker 1: have this author on because so many great people died 10 00:00:35,040 --> 00:00:37,639 Speaker 1: from TV, which I know is not the most respectful 11 00:00:37,680 --> 00:00:39,960 Speaker 1: way to look at it, but I was really excited 12 00:00:39,960 --> 00:00:41,800 Speaker 1: about this book. When I was a child, I was 13 00:00:42,000 --> 00:00:46,600 Speaker 1: afraid of tb because my grandmother, long before I was 14 00:00:46,640 --> 00:00:48,479 Speaker 1: born or my mother was born, and my grandmother was 15 00:00:48,520 --> 00:00:52,400 Speaker 1: a child, she had to live in a tuberculosis sanatorium 16 00:00:52,440 --> 00:00:55,520 Speaker 1: for a while because she had TV. And I like 17 00:00:55,600 --> 00:00:58,400 Speaker 1: heard this story and in my child mind, like TV 18 00:00:58,560 --> 00:01:02,760 Speaker 1: became a thing that my consume Me yeah, and I 19 00:01:02,960 --> 00:01:04,600 Speaker 1: like that, was afraid of that, and I was afraid 20 00:01:04,600 --> 00:01:09,040 Speaker 1: of dying in childbirth for some reason. With the good 21 00:01:09,040 --> 00:01:13,000 Speaker 1: news is you don't how to do either of those things. Um, 22 00:01:13,080 --> 00:01:15,880 Speaker 1: and it turns out that this book is also a 23 00:01:15,880 --> 00:01:19,360 Speaker 1: delight to read. So if you're concerned that a book 24 00:01:19,360 --> 00:01:22,160 Speaker 1: about a medical thing in history might be dry or boring, 25 00:01:22,240 --> 00:01:26,040 Speaker 1: it is absolutely not. Catherine Locked the author. Her ability 26 00:01:26,080 --> 00:01:29,120 Speaker 1: to demystify scientific concepts and make them super easy for 27 00:01:29,120 --> 00:01:32,600 Speaker 1: people who are not scientists to understand is really fantastic. 28 00:01:32,720 --> 00:01:35,040 Speaker 1: I asked her about it in the interview and she 29 00:01:35,200 --> 00:01:36,720 Speaker 1: said it was hard, but it does not come off 30 00:01:36,760 --> 00:01:39,759 Speaker 1: his heart. And her writing style really surprised me because 31 00:01:39,760 --> 00:01:43,240 Speaker 1: she's quite witty. She is a microbiologist. She has a 32 00:01:43,280 --> 00:01:47,240 Speaker 1: decade of research and tuberculosis specifically, so her knowledge even 33 00:01:47,280 --> 00:01:50,680 Speaker 1: prior to researching this book is really vast and it 34 00:01:50,760 --> 00:01:55,680 Speaker 1: spans centuries. So many many months later, Holly finally managed 35 00:01:55,720 --> 00:01:57,360 Speaker 1: to get all the pieces in place to have her 36 00:01:57,400 --> 00:01:59,880 Speaker 1: on the show. She was gracious enough to roll with 37 00:02:00,080 --> 00:02:03,200 Speaker 1: having to schedule around a five hour time difference for 38 00:02:03,280 --> 00:02:06,560 Speaker 1: a phone interview, so we are delighted and thankful that 39 00:02:06,600 --> 00:02:09,720 Speaker 1: she did so. Thankful that's it seems like it should 40 00:02:09,720 --> 00:02:11,960 Speaker 1: be easy, but it really does become tricky when you're 41 00:02:11,960 --> 00:02:15,960 Speaker 1: scheduling around people's lives. Five hours suddenly can become a lot. 42 00:02:16,400 --> 00:02:18,160 Speaker 1: So we're going to operate in there and learn a 43 00:02:18,200 --> 00:02:21,720 Speaker 1: little bit about how tuberculosis became such a massive threat 44 00:02:21,760 --> 00:02:30,000 Speaker 1: to humanity right out of the gates. Your background is microbiology, 45 00:02:30,000 --> 00:02:32,200 Speaker 1: but will you share with us what piqued your interests 46 00:02:32,280 --> 00:02:38,640 Speaker 1: in tuberculosis specifically? Okay? Um? So, So, I always wanted 47 00:02:38,680 --> 00:02:41,760 Speaker 1: to be a micronologist since I was really young, just 48 00:02:41,919 --> 00:02:44,960 Speaker 1: always been fascinated by the idea of this sort of 49 00:02:45,040 --> 00:02:50,240 Speaker 1: invisible world bacteria that surrounds us, just out of sight. Um. 50 00:02:51,040 --> 00:02:53,160 Speaker 1: And when it came to deciding what I wanted to 51 00:02:53,160 --> 00:02:56,079 Speaker 1: work on, I simply worked for tuberculosis because it was 52 00:02:56,160 --> 00:02:59,600 Speaker 1: the biggest infectious disease killer around and it's it's just 53 00:02:59,680 --> 00:03:03,880 Speaker 1: quite fascinating thinking about how you get get these pathogens 54 00:03:03,880 --> 00:03:07,080 Speaker 1: which end up killing their hosts, which isn't something that 55 00:03:07,200 --> 00:03:10,880 Speaker 1: bacteria specifically sets out to do. And I just wanted 56 00:03:10,919 --> 00:03:13,520 Speaker 1: to be part of the work that goes into trying 57 00:03:13,520 --> 00:03:16,840 Speaker 1: to combat the biggest infectious disease killer. And do you 58 00:03:16,880 --> 00:03:20,280 Speaker 1: find it challenging as a scientist too? Then when you're 59 00:03:20,280 --> 00:03:27,120 Speaker 1: writing a book conveys scientific concepts to potential non scientist readers, Yeah, 60 00:03:27,200 --> 00:03:29,680 Speaker 1: that that did turn out to be a big sort. 61 00:03:30,000 --> 00:03:32,400 Speaker 1: It was difficult when I was writing the book to 62 00:03:32,440 --> 00:03:34,920 Speaker 1: try and make sure I didn't go to science, and 63 00:03:35,240 --> 00:03:36,560 Speaker 1: I know that a lot of the people who have 64 00:03:36,600 --> 00:03:39,880 Speaker 1: read it and actually scientists then complain that it's not 65 00:03:39,960 --> 00:03:43,360 Speaker 1: science enough. So yeah, it's difficult getting the balance. But 66 00:03:43,440 --> 00:03:44,840 Speaker 1: I think what I've tried to do in the book 67 00:03:44,920 --> 00:03:48,920 Speaker 1: is find some of the interesting stories from speculosis history 68 00:03:49,000 --> 00:03:51,760 Speaker 1: and try and use them to get across what's turned 69 00:03:51,800 --> 00:03:55,120 Speaker 1: it into this world's biggest killer. And in the introduction 70 00:03:55,160 --> 00:03:58,280 Speaker 1: to your book, you characterize yourself as wanting to rebrand 71 00:03:58,320 --> 00:04:02,080 Speaker 1: tuberculosis for modern public awareness. Can you speak a little 72 00:04:02,080 --> 00:04:05,440 Speaker 1: bit about why it needs rebranding. So when I tend 73 00:04:05,480 --> 00:04:08,720 Speaker 1: to tell people that I've worked on subaculosis at a 74 00:04:08,800 --> 00:04:12,840 Speaker 1: party or at a baby group, quite often, Um, a 75 00:04:12,880 --> 00:04:15,280 Speaker 1: lot of people seem to see TV is this old 76 00:04:15,280 --> 00:04:20,839 Speaker 1: fashioned disease that affected poets in the nineteenth century, and 77 00:04:21,240 --> 00:04:24,440 Speaker 1: that it sort of disappeared when we invented antibiotics and 78 00:04:24,680 --> 00:04:27,960 Speaker 1: is no longer a problem. And it was a huge 79 00:04:27,960 --> 00:04:30,279 Speaker 1: problem in the nineteenth century. But I don't think a 80 00:04:30,279 --> 00:04:32,480 Speaker 1: lot of people realize that it's still with us and 81 00:04:32,520 --> 00:04:35,960 Speaker 1: it's still killing something like one point seven million people 82 00:04:36,160 --> 00:04:39,360 Speaker 1: a year and causing ten million new cases every year. 83 00:04:39,760 --> 00:04:42,040 Speaker 1: So I kind of wanted to rebrand TV. Is this 84 00:04:42,120 --> 00:04:45,320 Speaker 1: modern day monster rather than this relic of the past. 85 00:04:45,400 --> 00:04:48,839 Speaker 1: And the history of TV is really fascinating, but I 86 00:04:48,880 --> 00:04:51,440 Speaker 1: do think we need to remember that it's not a 87 00:04:51,440 --> 00:04:55,160 Speaker 1: disease of history. And when you talk a little bit 88 00:04:55,200 --> 00:04:58,440 Speaker 1: about how TV and Homo sapiens have this sort of 89 00:04:58,800 --> 00:05:01,760 Speaker 1: hand in hand relationship that you talk about through evolution, 90 00:05:04,400 --> 00:05:08,839 Speaker 1: mm hmm, okay, So it's it's thought that TV was 91 00:05:08,880 --> 00:05:12,760 Speaker 1: probably infecting humans back when we were first starting out 92 00:05:12,800 --> 00:05:16,360 Speaker 1: in Africa's cradle of life. And the idea is that 93 00:05:17,040 --> 00:05:19,440 Speaker 1: TV then went to spread around the world with the 94 00:05:19,480 --> 00:05:22,479 Speaker 1: first humans who will leading Africa during the out of 95 00:05:22,520 --> 00:05:25,560 Speaker 1: Africa migrations. And you can still see all of these 96 00:05:25,600 --> 00:05:28,920 Speaker 1: different lineages of TV in various parts of the world. 97 00:05:28,960 --> 00:05:34,000 Speaker 1: And despite all the globalization that spread us humans everywhere, um, 98 00:05:34,080 --> 00:05:38,800 Speaker 1: we still see these specific lineages of TV infecting specific populations. 99 00:05:39,240 --> 00:05:41,960 Speaker 1: And the idea is that TV has effectively grown up 100 00:05:42,000 --> 00:05:46,839 Speaker 1: alongside humanity. It's been with us throughout our entire history 101 00:05:46,880 --> 00:05:49,479 Speaker 1: and in a way has learned from us. And that's 102 00:05:49,480 --> 00:05:52,440 Speaker 1: one of the reasons why it's so difficult to eradicate 103 00:05:52,520 --> 00:05:54,920 Speaker 1: TB today just because it's been with us so long. 104 00:05:57,080 --> 00:06:00,840 Speaker 1: Then why do you think it became so prevalent as 105 00:06:00,839 --> 00:06:03,480 Speaker 1: a global threat before we figured out a way to 106 00:06:03,520 --> 00:06:09,400 Speaker 1: deal with it. So I think the biggest thing that 107 00:06:09,800 --> 00:06:13,520 Speaker 1: turned t D into the problem is today was when 108 00:06:13,640 --> 00:06:17,240 Speaker 1: humans stopped living hunt to gather a lifestyles and moved 109 00:06:17,279 --> 00:06:21,279 Speaker 1: to living at first in small villages, and then thanks 110 00:06:21,320 --> 00:06:25,800 Speaker 1: to urbanization and industrialization, we've got the rise of these 111 00:06:26,000 --> 00:06:28,880 Speaker 1: big cities which many of us live in today. And 112 00:06:29,680 --> 00:06:34,720 Speaker 1: it was humans living in unhealthy, overcrowded conditions which really 113 00:06:34,760 --> 00:06:38,000 Speaker 1: gave TV everything it needed to flourish and become this 114 00:06:38,200 --> 00:06:41,240 Speaker 1: mass killer when it was infecting Hunt together as it 115 00:06:41,320 --> 00:06:44,600 Speaker 1: had a very small pool of hosts to infects, and 116 00:06:45,160 --> 00:06:47,840 Speaker 1: it was just one of many diseases that when we 117 00:06:47,880 --> 00:06:52,160 Speaker 1: started living in towns and cities, suddenly found itself. With 118 00:06:52,240 --> 00:06:54,800 Speaker 1: all of these hosts, it could spread you very easily, 119 00:06:55,240 --> 00:06:57,440 Speaker 1: and that's kind of what turned it into what it 120 00:06:57,520 --> 00:07:02,120 Speaker 1: is today. I was really delighted that you mentioned in 121 00:07:02,120 --> 00:07:04,719 Speaker 1: your book the Jewitt City vampires and the New England 122 00:07:04,800 --> 00:07:10,080 Speaker 1: vampire panic. They were actually a topic of a previous episode. Um, 123 00:07:11,840 --> 00:07:14,000 Speaker 1: will you talk a little bit about how you see 124 00:07:14,080 --> 00:07:17,520 Speaker 1: that point in history as really representative of how humans 125 00:07:17,800 --> 00:07:24,960 Speaker 1: have dealt with tuberculosis historically. Yes. So I loved the 126 00:07:24,960 --> 00:07:27,560 Speaker 1: story of the New England Vampires when I came across there, 127 00:07:27,560 --> 00:07:29,960 Speaker 1: and I touched on it in the book, more from 128 00:07:30,000 --> 00:07:33,120 Speaker 1: the TV side of things than the actual the history 129 00:07:33,160 --> 00:07:38,440 Speaker 1: of the New England Vampires. So I included this story 130 00:07:38,560 --> 00:07:42,840 Speaker 1: because I feel like it represented the sheer panic that 131 00:07:42,880 --> 00:07:47,560 Speaker 1: would surround this disease back in the nineteenth century. So 132 00:07:47,680 --> 00:07:50,880 Speaker 1: TV was a disease which was killing a huge number 133 00:07:50,960 --> 00:07:54,120 Speaker 1: of people. It's been estimated it's killed something like one 134 00:07:54,160 --> 00:07:56,960 Speaker 1: in certain people who have ever lived by this point 135 00:07:56,960 --> 00:08:00,400 Speaker 1: in history, and it was a disease that could down 136 00:08:00,480 --> 00:08:04,880 Speaker 1: whole families, sometimes months apart or years apart. But nobody 137 00:08:04,960 --> 00:08:07,880 Speaker 1: knew anything about bacteria at this point, and they didn't 138 00:08:07,880 --> 00:08:10,200 Speaker 1: know it was an infectious disease. They didn't know it 139 00:08:10,240 --> 00:08:15,480 Speaker 1: was spreading through people coughing or living in overcrowded little houses. Um, 140 00:08:16,400 --> 00:08:19,320 Speaker 1: And there wasn't anything anyone could do about it. So 141 00:08:19,520 --> 00:08:22,560 Speaker 1: once you got it, you were quite possibly going to 142 00:08:22,600 --> 00:08:26,320 Speaker 1: die from it, and people were willing to try anything 143 00:08:26,400 --> 00:08:28,640 Speaker 1: to try and save their loved ones from this disease. 144 00:08:29,040 --> 00:08:32,840 Speaker 1: So I think that's where this whole folk belief of 145 00:08:32,960 --> 00:08:36,320 Speaker 1: the vampires rising from the grave at night to feed 146 00:08:36,400 --> 00:08:39,839 Speaker 1: upon the living came from um in terms of consumption 147 00:08:39,880 --> 00:08:43,679 Speaker 1: and TV. So the idea behind the folk belief was 148 00:08:43,800 --> 00:08:47,480 Speaker 1: that someone who had previously died of TB or consumption 149 00:08:47,559 --> 00:08:50,880 Speaker 1: is they have known back down, was coming back to 150 00:08:50,960 --> 00:08:54,840 Speaker 1: life at night to come and feed on family members 151 00:08:54,880 --> 00:08:56,960 Speaker 1: who were still alive. And the way to stop this 152 00:08:57,160 --> 00:09:01,320 Speaker 1: mischievous undead person was to go to the graveyard and 153 00:09:02,600 --> 00:09:08,880 Speaker 1: carry out various quite gaulish unto digging up the body, 154 00:09:09,520 --> 00:09:11,880 Speaker 1: removing the heart, turning it into a potion, and then 155 00:09:11,880 --> 00:09:14,880 Speaker 1: feeding this to the person who had t V. And 156 00:09:14,920 --> 00:09:17,120 Speaker 1: it was just I think it was just the case 157 00:09:17,160 --> 00:09:19,839 Speaker 1: of people wanting to try anything to save their loved 158 00:09:19,840 --> 00:09:23,840 Speaker 1: ones when there wasn't any science that could do anything 159 00:09:23,880 --> 00:09:33,040 Speaker 1: for them. I loved that Catherine included the New England 160 00:09:33,080 --> 00:09:36,160 Speaker 1: vampire panic in her book. It made me so excited. 161 00:09:36,160 --> 00:09:37,280 Speaker 1: When I got to that part, I was like, I 162 00:09:37,320 --> 00:09:40,120 Speaker 1: know about this. We are going to have more with 163 00:09:40,360 --> 00:09:43,920 Speaker 1: microbiologist and history author Katherine Lackey, but first we will 164 00:09:44,000 --> 00:09:54,880 Speaker 1: pause for a quick sponsor break. In this next segment 165 00:09:55,040 --> 00:09:58,080 Speaker 1: of my interview with Katherine Lacked, she shares her thoughts 166 00:09:58,080 --> 00:10:02,600 Speaker 1: on why tuberculosis bea so romanticized in the nineteenth century. 167 00:10:06,640 --> 00:10:10,520 Speaker 1: When you speak to the weird romanticism about tuberculosis that 168 00:10:10,600 --> 00:10:15,079 Speaker 1: did happen in the nineteenth century, yeah, I always find it. 169 00:10:15,200 --> 00:10:18,040 Speaker 1: It's it's probably what t D is best known for 170 00:10:18,760 --> 00:10:21,599 Speaker 1: among many people, this idea that it was this romantic, 171 00:10:22,040 --> 00:10:26,480 Speaker 1: passionate disease that could inspire creativity. And it was quite 172 00:10:26,480 --> 00:10:31,520 Speaker 1: prevalence in Victorian London the nineteenth century, and I think 173 00:10:31,559 --> 00:10:33,880 Speaker 1: part of the reason for that is that it's famously 174 00:10:34,960 --> 00:10:38,560 Speaker 1: killed a large number of poets. It was killing a 175 00:10:38,600 --> 00:10:41,040 Speaker 1: lot of other people as well, often the very poor 176 00:10:41,080 --> 00:10:43,520 Speaker 1: people in the city, although that wasn't quite sort of 177 00:10:43,600 --> 00:10:47,160 Speaker 1: romantic um. And so it was this disease where it 178 00:10:47,240 --> 00:10:49,520 Speaker 1: sort of found its way into the culture of the day, 179 00:10:49,520 --> 00:10:53,440 Speaker 1: and see these operatic heroines who were dying of consumption. 180 00:10:53,960 --> 00:10:59,200 Speaker 1: It was in a lot of literature and art, and 181 00:10:59,440 --> 00:11:01,520 Speaker 1: it just inspired a huge amount of the culture of 182 00:11:01,559 --> 00:11:05,280 Speaker 1: the day. I think women, the ideal of beauty among 183 00:11:05,320 --> 00:11:09,640 Speaker 1: women was seen to be this very pale, fragile consumptive look, 184 00:11:10,120 --> 00:11:12,880 Speaker 1: which is quite strange when you think about it today 185 00:11:12,920 --> 00:11:16,120 Speaker 1: that people were glamorizing this infection. But I think it 186 00:11:16,240 --> 00:11:19,040 Speaker 1: was just a response to a disease that was killing 187 00:11:19,040 --> 00:11:23,920 Speaker 1: such huge numbers of people. And I'm curious because I 188 00:11:23,960 --> 00:11:26,679 Speaker 1: know it has changed over time, but what has TV 189 00:11:26,760 --> 00:11:30,920 Speaker 1: treatment historically involved and how is it treated today comparatively. 190 00:11:34,200 --> 00:11:37,520 Speaker 1: So it took a really long time for any sort 191 00:11:37,559 --> 00:11:40,959 Speaker 1: of TV treatment that worked to be introduced. There were 192 00:11:41,000 --> 00:11:45,040 Speaker 1: all of these historical attempts at treating it that wouldn't 193 00:11:45,040 --> 00:11:47,840 Speaker 1: have done very much, and I think in Victorian England 194 00:11:47,880 --> 00:11:50,760 Speaker 1: you had a lot of remedies that were just never 195 00:11:50,840 --> 00:11:55,160 Speaker 1: going to work. The first real treatment, I suppose, was 196 00:11:55,360 --> 00:11:59,200 Speaker 1: the invention of the sanatorium where people could be sent 197 00:11:59,320 --> 00:12:05,320 Speaker 1: for the good diet, exposure to sunlight, exercise, and that 198 00:12:05,400 --> 00:12:08,480 Speaker 1: went some way to treating TV, but it obviously wasn't 199 00:12:08,480 --> 00:12:11,400 Speaker 1: a perfect cure. There were also at the turn of 200 00:12:11,440 --> 00:12:16,200 Speaker 1: the twentieth century some fairly barbaric surgical treatments used to 201 00:12:16,240 --> 00:12:19,280 Speaker 1: try and cure the disease, such as collapsing someone's lung, 202 00:12:19,480 --> 00:12:24,160 Speaker 1: sometimes permanently, um to just also kill the TV infection 203 00:12:24,240 --> 00:12:27,040 Speaker 1: that was in that lung and that was really the 204 00:12:27,080 --> 00:12:29,360 Speaker 1: only way that people could be cured if they had 205 00:12:29,400 --> 00:12:33,200 Speaker 1: a serious TV infection. And then in the nineties and 206 00:12:33,280 --> 00:12:38,520 Speaker 1: fifties you started seeing antibiotics being introduced and this revolutionized 207 00:12:38,520 --> 00:12:42,480 Speaker 1: the treatment of TV. And actually the antibiotics that were 208 00:12:42,520 --> 00:12:45,120 Speaker 1: introduced in the fifties are still the ones that are 209 00:12:45,120 --> 00:12:49,160 Speaker 1: commonly used today. So the treatment for a normal, um 210 00:12:49,360 --> 00:12:53,160 Speaker 1: non drug resistant case of TV today would be a 211 00:12:53,240 --> 00:12:57,640 Speaker 1: combination of four antibiotics that you would take for several months. 212 00:12:57,640 --> 00:13:00,040 Speaker 1: So you take four of them for two months and 213 00:13:00,080 --> 00:13:02,440 Speaker 1: then carry on taking two of the others for another 214 00:13:02,440 --> 00:13:05,800 Speaker 1: four months after that. UM, so six month treatments in 215 00:13:05,880 --> 00:13:09,760 Speaker 1: total with some fairly horrible, quite old fashioned antibiotics. And 216 00:13:10,160 --> 00:13:12,800 Speaker 1: we are seeing a few new ones being introduced now, 217 00:13:12,840 --> 00:13:15,200 Speaker 1: but not at a break that's quick enough to deal 218 00:13:15,320 --> 00:13:19,720 Speaker 1: with the problem of drug resistance. I'm glad you mentioned 219 00:13:19,800 --> 00:13:21,880 Speaker 1: drug resistant TV because that was what I was going 220 00:13:21,920 --> 00:13:24,400 Speaker 1: to bring up next. Will you talk a little bit 221 00:13:24,440 --> 00:13:28,400 Speaker 1: about how drug resistance TV has evolved and sort of 222 00:13:28,440 --> 00:13:35,600 Speaker 1: when we realized that was happening. Yes, So, drug resistance 223 00:13:35,920 --> 00:13:39,240 Speaker 1: is always it's pretty much inevitable with any bacterial infection. 224 00:13:39,280 --> 00:13:41,400 Speaker 1: The problem is is when it gets set in place 225 00:13:41,440 --> 00:13:45,160 Speaker 1: in the population and takes hold. And today we're seeing 226 00:13:45,240 --> 00:13:48,800 Speaker 1: huge numbers of cases of drug resistant TB. I don't 227 00:13:48,800 --> 00:13:52,040 Speaker 1: think we fully understand how much there is out there, 228 00:13:52,120 --> 00:13:56,520 Speaker 1: just because it's not very well documented at the moment um. 229 00:13:56,840 --> 00:14:00,960 Speaker 1: So we can have cases today called multi drug resistant TV, 230 00:14:01,160 --> 00:14:04,120 Speaker 1: which was the resistant to a couple of the frontline 231 00:14:04,160 --> 00:14:06,880 Speaker 1: drugs that you used to treat it UM, and this 232 00:14:07,040 --> 00:14:10,120 Speaker 1: can go all the way to completely or totally drug 233 00:14:10,160 --> 00:14:16,280 Speaker 1: resistant TV, which is practically untreatable by current the drug 234 00:14:16,360 --> 00:14:20,160 Speaker 1: the current drug regimens. So the first time people started 235 00:14:20,200 --> 00:14:25,840 Speaker 1: to realize it was a problem UM So I can't 236 00:14:25,840 --> 00:14:29,400 Speaker 1: remember the exact dates actually that we first started seeing 237 00:14:29,560 --> 00:14:33,440 Speaker 1: a strain of TV called xdr TV emerging in parts 238 00:14:33,520 --> 00:14:38,240 Speaker 1: of Africa, which managed to get itself into the news 239 00:14:38,280 --> 00:14:40,200 Speaker 1: just because a huge number of the people who are 240 00:14:40,200 --> 00:14:44,600 Speaker 1: infected with these strains of TV were dying from it UM. 241 00:14:44,640 --> 00:14:48,720 Speaker 1: There's also been a lot of recent talking India about 242 00:14:48,800 --> 00:14:53,160 Speaker 1: their huge drug resistance problem, which wasn't People didn't realize 243 00:14:53,160 --> 00:14:57,600 Speaker 1: it was such a problem until plainly recently. How TV 244 00:14:57,720 --> 00:15:02,320 Speaker 1: drug resistant strains emerged is that you get resistance in 245 00:15:02,440 --> 00:15:06,440 Speaker 1: just one bacterium and then this multiplies and then start 246 00:15:06,480 --> 00:15:09,920 Speaker 1: spreading to other people if it's left unchecked. And one 247 00:15:09,920 --> 00:15:12,600 Speaker 1: really good example of this was in was following the 248 00:15:12,600 --> 00:15:16,480 Speaker 1: collapse of the Soviet Union. So before before the collapse, 249 00:15:16,560 --> 00:15:19,720 Speaker 1: you had a really good TV program, everything was well controlled, 250 00:15:19,840 --> 00:15:23,800 Speaker 1: people had access to decent health care. However, when everything 251 00:15:23,880 --> 00:15:27,640 Speaker 1: fell into ruin, people didn't have access to the same medicines, 252 00:15:27,720 --> 00:15:30,760 Speaker 1: and drug resistance strains were able to have emerged and 253 00:15:31,200 --> 00:15:34,880 Speaker 1: go unchecked. And we can actually trace back modern day 254 00:15:34,960 --> 00:15:37,840 Speaker 1: drug resistance strains to this point in time and see 255 00:15:37,840 --> 00:15:40,320 Speaker 1: that they saw of a number of them started off 256 00:15:40,520 --> 00:15:44,040 Speaker 1: in the form of Soviet Union and then just gradually 257 00:15:44,080 --> 00:15:48,840 Speaker 1: grew over time and developed resistance to further drugs until 258 00:15:48,880 --> 00:15:51,200 Speaker 1: they reached a point where they're not really that treatable 259 00:15:51,200 --> 00:15:53,600 Speaker 1: with any of the drug regiments that we have available today. 260 00:15:55,720 --> 00:15:59,640 Speaker 1: You mentioned in your book that TV treatment even now 261 00:15:59,800 --> 00:16:02,640 Speaker 1: is really really rough on the patient. UM. Will you 262 00:16:02,680 --> 00:16:06,080 Speaker 1: talk about some of the risks in both previous versions 263 00:16:06,120 --> 00:16:09,920 Speaker 1: of treatment, including collapse lungs, like what was the mortality 264 00:16:10,000 --> 00:16:17,280 Speaker 1: like versus the actual cure um. I don't know the 265 00:16:17,440 --> 00:16:22,080 Speaker 1: exact numbers, but without treatment for people who have a 266 00:16:22,200 --> 00:16:26,560 Speaker 1: sort of serious TV infection around will die. Um, this 267 00:16:26,640 --> 00:16:29,360 Speaker 1: is less if they have a TV infection, that's um, 268 00:16:29,560 --> 00:16:32,640 Speaker 1: sort of a little bit more below the radar, I suppose. 269 00:16:33,000 --> 00:16:36,520 Speaker 1: And then it's then around these people will die from 270 00:16:36,680 --> 00:16:39,920 Speaker 1: if left untreated. So it works out around people with 271 00:16:40,000 --> 00:16:42,600 Speaker 1: an untreated TD infection will go on to die from it. 272 00:16:43,040 --> 00:16:46,320 Speaker 1: And today TV is essentially a treatable disease and we 273 00:16:46,360 --> 00:16:50,040 Speaker 1: shouldn't be seeing any death. However, we are seeing one 274 00:16:50,080 --> 00:16:52,680 Speaker 1: point seven million a year and unfortunately a lot of 275 00:16:52,720 --> 00:16:55,200 Speaker 1: that not down to the disease itself, but it's down 276 00:16:55,240 --> 00:16:57,080 Speaker 1: to all the social factors that are wrapped up to 277 00:16:57,200 --> 00:16:59,520 Speaker 1: TV and the fact that a lot of people aren't 278 00:16:59,520 --> 00:17:02,240 Speaker 1: being died nosed, or they don't have access to the 279 00:17:02,280 --> 00:17:08,240 Speaker 1: proper treatment regiments. Um, what do you think is the 280 00:17:08,280 --> 00:17:16,439 Speaker 1: most important moment in tuberculosis? Is long, long history. That's 281 00:17:16,440 --> 00:17:19,560 Speaker 1: that's an interesting question. I I suppose. I would say 282 00:17:19,600 --> 00:17:22,880 Speaker 1: the neo ethnic revolution where people stopped living these come 283 00:17:22,960 --> 00:17:27,800 Speaker 1: together a lifestyles and moved to having little villages and 284 00:17:27,920 --> 00:17:31,200 Speaker 1: relying on agriculture and farming to survive. And that was 285 00:17:31,240 --> 00:17:35,320 Speaker 1: really set in motion TV's rise to becoming this huge 286 00:17:35,320 --> 00:17:38,960 Speaker 1: global killer. The Industrial revolution as well was an assid 287 00:17:39,000 --> 00:17:42,240 Speaker 1: turning point for TV, because he started getting these huge 288 00:17:42,240 --> 00:17:46,879 Speaker 1: cities and people were living in really horrible, overcrowded conditions 289 00:17:46,920 --> 00:17:49,720 Speaker 1: and it was a very unhealthy lifestyle, and this made 290 00:17:49,760 --> 00:17:52,119 Speaker 1: them more likely to catch TB and then to go 291 00:17:52,240 --> 00:17:55,160 Speaker 1: on to die from it. Um, we actually started seeing 292 00:17:55,160 --> 00:17:58,760 Speaker 1: a decline in TB in cases like the UK and 293 00:17:59,119 --> 00:18:02,760 Speaker 1: the S following the Industrial Revolution, when people started living 294 00:18:02,840 --> 00:18:08,880 Speaker 1: healthier lifestyles and having better health care, better cleanness, last 295 00:18:08,880 --> 00:18:12,639 Speaker 1: polluted cities, etcetera. And so that was sort of big 296 00:18:12,720 --> 00:18:15,520 Speaker 1: turning point for humans, I suppose in our fight against TV, 297 00:18:16,359 --> 00:18:19,280 Speaker 1: and in the modern world in the UK and US 298 00:18:19,280 --> 00:18:22,399 Speaker 1: another high income countries, TV is no longer such a 299 00:18:22,480 --> 00:18:25,639 Speaker 1: huge problem, So I think. I mean, this is one 300 00:18:25,680 --> 00:18:27,560 Speaker 1: of the big problems with TV is that it is 301 00:18:27,560 --> 00:18:32,760 Speaker 1: a disease of inequality and poverty and social factors. It's 302 00:18:32,800 --> 00:18:36,480 Speaker 1: not just the bacteria. So when you say that's why 303 00:18:36,680 --> 00:18:39,520 Speaker 1: there is this misconception that it's sort of history's disease, 304 00:18:39,840 --> 00:18:41,960 Speaker 1: because the people that are talking about it are usually 305 00:18:42,040 --> 00:18:48,440 Speaker 1: more effluent than the people actually dealing with it. Yeah, 306 00:18:48,600 --> 00:18:52,720 Speaker 1: I think so it's um, Yeah, it's it's difficult because 307 00:18:52,920 --> 00:18:57,080 Speaker 1: sort of campaigning for a disease which isn't really that 308 00:18:57,200 --> 00:19:00,719 Speaker 1: much of a problem in the UK um countries such 309 00:19:00,760 --> 00:19:03,359 Speaker 1: as the US as well. But unfortunately it's going to 310 00:19:03,400 --> 00:19:06,280 Speaker 1: take high income countries to be able to combat the 311 00:19:06,320 --> 00:19:08,520 Speaker 1: problem with everyone's going to have to work together and 312 00:19:08,760 --> 00:19:10,240 Speaker 1: we're not going to be able to get rid of 313 00:19:10,280 --> 00:19:13,520 Speaker 1: TV in places like the US UK unless we get 314 00:19:13,600 --> 00:19:15,240 Speaker 1: rid of it in the countries where it is a 315 00:19:15,320 --> 00:19:22,879 Speaker 1: huge problem. So India, China, South Africa, Pakistan, Indonesia and 316 00:19:22,960 --> 00:19:25,919 Speaker 1: Nigeria are the places where TV is currently the biggest 317 00:19:25,920 --> 00:19:28,800 Speaker 1: problem in THESA or low income countries Prepared with our 318 00:19:28,800 --> 00:19:36,560 Speaker 1: own I think it's a really great point to make 319 00:19:36,640 --> 00:19:40,159 Speaker 1: that TV cannot be eradicated in affluent countries unless we 320 00:19:40,240 --> 00:19:43,320 Speaker 1: also address it in countries where it's much more prevalent. Yeah, 321 00:19:43,600 --> 00:19:46,320 Speaker 1: we are also going to talk with microbol Just Catherine 322 00:19:46,400 --> 00:19:49,119 Speaker 1: lackeyed some more in just a moment after we pause 323 00:19:49,240 --> 00:20:01,040 Speaker 1: for one more quick sponsor break, So coming up find 324 00:20:01,040 --> 00:20:03,320 Speaker 1: out what sort of testing we're really going to need 325 00:20:03,800 --> 00:20:06,960 Speaker 1: to address the one point seven million annual deaths that 326 00:20:07,080 --> 00:20:13,720 Speaker 1: still happen from tuberculosis. In your book, you make the 327 00:20:13,720 --> 00:20:16,720 Speaker 1: case for raising TV awareness and making testing the kind 328 00:20:16,760 --> 00:20:19,800 Speaker 1: of thing that people should be doing, even if they're asymptomatic. 329 00:20:19,800 --> 00:20:22,720 Speaker 1: Will you talk a little bit about that. Yeah? So. 330 00:20:23,040 --> 00:20:25,800 Speaker 1: Um one of the big problems with TV is that 331 00:20:25,840 --> 00:20:29,040 Speaker 1: we don't have any really good diagnostic tests that is 332 00:20:29,080 --> 00:20:32,880 Speaker 1: able to accurately tell us whether someone has the disease. 333 00:20:33,119 --> 00:20:35,720 Speaker 1: I mean, there are methods of diagnosing it, but they're 334 00:20:35,760 --> 00:20:40,200 Speaker 1: not always that good for use in countries where, for example, 335 00:20:40,240 --> 00:20:43,800 Speaker 1: there isn't a dedicated power supply um or it's extremely 336 00:20:43,800 --> 00:20:46,080 Speaker 1: hot and dusty, and you can't be using these high 337 00:20:46,160 --> 00:20:50,520 Speaker 1: tech pieces of labor tooitments unless someone really well trained 338 00:20:50,520 --> 00:20:52,960 Speaker 1: in them and you've got all the infrastructure and support 339 00:20:53,359 --> 00:20:56,680 Speaker 1: that's required to sort of analyze the test results after 340 00:20:56,720 --> 00:21:00,960 Speaker 1: you run the test itself. UM So, yeah, I would. 341 00:21:01,000 --> 00:21:04,000 Speaker 1: I would love to see a world where people who 342 00:21:04,240 --> 00:21:07,680 Speaker 1: are thought to have TV are tested using these modern, 343 00:21:08,720 --> 00:21:12,439 Speaker 1: great new diagnostics. Um. I think it's more likely that 344 00:21:12,480 --> 00:21:15,119 Speaker 1: we're going to have to develop new diagnostic tests that 345 00:21:15,160 --> 00:21:18,320 Speaker 1: can be used out in places where they don't have 346 00:21:18,359 --> 00:21:21,800 Speaker 1: access to these to the new technologies, and it would 347 00:21:21,800 --> 00:21:24,240 Speaker 1: be nice to see everyone being tested. You have sensems 348 00:21:24,240 --> 00:21:27,080 Speaker 1: of TV. But importantly, I'd also like to see a 349 00:21:27,440 --> 00:21:30,920 Speaker 1: sort of a drug resistance profile being taken to new 350 00:21:30,960 --> 00:21:33,159 Speaker 1: cases of TV, so we can pick up whether someone's 351 00:21:33,160 --> 00:21:35,760 Speaker 1: infection is going to be a drug resistant one before 352 00:21:35,800 --> 00:21:38,879 Speaker 1: they start treatment with the traditional drugs, which won't work 353 00:21:39,200 --> 00:21:44,119 Speaker 1: if it's not sensitive strain, if it's a drug resistance strain. 354 00:21:46,000 --> 00:21:49,639 Speaker 1: And to wrap up, is there any We talked a 355 00:21:49,680 --> 00:21:51,920 Speaker 1: little bit about the Jewit City vampires and some other 356 00:21:52,000 --> 00:21:54,840 Speaker 1: historical moments that you think are important. But do you 357 00:21:54,880 --> 00:21:59,560 Speaker 1: have a favorite sort of time in history to talk 358 00:21:59,600 --> 00:22:02,920 Speaker 1: about or do you know that has a unique story 359 00:22:02,960 --> 00:22:07,600 Speaker 1: of TV within it. Yeah, So when I was starting 360 00:22:07,600 --> 00:22:10,000 Speaker 1: out writing the book, I sort of thought to myself, 361 00:22:11,080 --> 00:22:13,119 Speaker 1: I wanted to go back in time and find the 362 00:22:13,160 --> 00:22:15,640 Speaker 1: first case of TV and have a look at how 363 00:22:15,720 --> 00:22:19,160 Speaker 1: far back we could actually diagnose this disease. And one 364 00:22:19,200 --> 00:22:22,040 Speaker 1: of the problems is that bacteria don't leave behind fossils, 365 00:22:22,080 --> 00:22:24,840 Speaker 1: so you can't chase them all the way back into history. 366 00:22:25,320 --> 00:22:29,600 Speaker 1: But the earliest diagnosed case in a human comes from 367 00:22:29,600 --> 00:22:32,919 Speaker 1: this little village called athlete Yam that's dust off the 368 00:22:32,960 --> 00:22:35,680 Speaker 1: coast of Israel, So it's been submerged under the sea 369 00:22:35,760 --> 00:22:39,520 Speaker 1: for something like nine thousand years because of the conditions, 370 00:22:39,520 --> 00:22:43,639 Speaker 1: so my layer of sediments and cool water. It meant 371 00:22:43,680 --> 00:22:47,560 Speaker 1: that the bodies buried in this village were extremely well preserved, 372 00:22:47,920 --> 00:22:50,920 Speaker 1: so when they were excavated in the night, people were 373 00:22:50,920 --> 00:22:54,439 Speaker 1: able to detect tiny amounts of bacterial DNA from the 374 00:22:54,480 --> 00:22:58,680 Speaker 1: TV pathogen in two of the people who were buried there, 375 00:22:58,720 --> 00:23:01,480 Speaker 1: so a mother and a bait be and find that 376 00:23:01,560 --> 00:23:06,520 Speaker 1: these are quite possibly the earliest diagnosed case of TV around. 377 00:23:06,600 --> 00:23:09,359 Speaker 1: And I really liked that story because I came at 378 00:23:09,400 --> 00:23:12,400 Speaker 1: writing the book from a very scientific perspective, and as 379 00:23:12,440 --> 00:23:14,680 Speaker 1: I went about writing it, I started to think more 380 00:23:14,720 --> 00:23:17,240 Speaker 1: about the actual people who were involved in the story. 381 00:23:17,720 --> 00:23:20,560 Speaker 1: Um so yeah, it was. It was very interesting to 382 00:23:20,600 --> 00:23:24,000 Speaker 1: find out about this village where this oldest case of 383 00:23:24,040 --> 00:23:26,920 Speaker 1: TV was found. Obviously TV goes back a lot further 384 00:23:27,040 --> 00:23:29,760 Speaker 1: in time, but it's much harder to diagnose it in 385 00:23:30,000 --> 00:23:34,720 Speaker 1: ancient remains. And then finally, where can people find you 386 00:23:34,720 --> 00:23:36,480 Speaker 1: if they want to learn more about your book or 387 00:23:36,520 --> 00:23:40,920 Speaker 1: your work? I have a blog called Germsoo dot blogspot 388 00:23:40,960 --> 00:23:43,560 Speaker 1: dot co dot uk where people can come and find me, 389 00:23:44,080 --> 00:23:47,600 Speaker 1: and I sometimes blog about science and my book and 390 00:23:48,119 --> 00:23:59,120 Speaker 1: other thoughts about the world of TV in general. Many 391 00:23:59,160 --> 00:24:01,280 Speaker 1: many things to care from lockeed for taking time to 392 00:24:01,320 --> 00:24:03,360 Speaker 1: speak with me. Uh. We're going to have a link 393 00:24:03,400 --> 00:24:05,200 Speaker 1: to her blog that she mentioned in the show notes 394 00:24:05,240 --> 00:24:08,000 Speaker 1: for this episode, so you can get there really easily 395 00:24:08,640 --> 00:24:10,680 Speaker 1: and learn about all the things that she has to share, 396 00:24:10,760 --> 00:24:15,200 Speaker 1: because she is really incredibly fun to read. Writer awesome. Yeah, 397 00:24:15,359 --> 00:24:17,119 Speaker 1: do you have listener mail for us? I do, and 398 00:24:17,160 --> 00:24:19,840 Speaker 1: it won't scare us about the possibility of contracting TV 399 00:24:19,960 --> 00:24:23,360 Speaker 1: and not knowing it. It will delight us with gifts. 400 00:24:23,960 --> 00:24:25,840 Speaker 1: I'm doing a little bit of an unboxing because this 401 00:24:25,880 --> 00:24:28,600 Speaker 1: is an unusual and wonderful day when Tracy is actually 402 00:24:28,640 --> 00:24:30,760 Speaker 1: in Atlanta and in the office with me. We are 403 00:24:30,760 --> 00:24:33,520 Speaker 1: in a studio looking at one another across the table. 404 00:24:33,520 --> 00:24:36,679 Speaker 1: It's pretty exciting. So instead of opening a parcel and 405 00:24:36,720 --> 00:24:38,520 Speaker 1: holding it up for her in front of a camera 406 00:24:38,640 --> 00:24:41,320 Speaker 1: on a computer, I can just show her cute things. 407 00:24:42,000 --> 00:24:44,280 Speaker 1: This is from our listener Christina, when she writes, Hi, 408 00:24:44,359 --> 00:24:46,359 Speaker 1: Holly and Tracy, I just wanted to say how much 409 00:24:46,400 --> 00:24:49,080 Speaker 1: I enjoy listening to your podcast. I am an illustrator. 410 00:24:49,119 --> 00:24:51,000 Speaker 1: And then she tells us where she lives and where 411 00:24:51,040 --> 00:24:52,760 Speaker 1: she works. I'm not going to include that in the 412 00:24:52,800 --> 00:24:55,480 Speaker 1: interest of her privacy, but she says, one of my 413 00:24:55,520 --> 00:24:57,919 Speaker 1: former students turned me onto your podcast, and I've been 414 00:24:58,000 --> 00:25:01,200 Speaker 1: binging it ever since. We illus traders work long hours 415 00:25:01,200 --> 00:25:03,480 Speaker 1: straight through on projects, and it always helps to have 416 00:25:03,600 --> 00:25:06,639 Speaker 1: educational and entertaining audio to keep us company in the 417 00:25:06,640 --> 00:25:09,040 Speaker 1: wee hours of the morning or when we're on a 418 00:25:09,040 --> 00:25:11,919 Speaker 1: twelve on a two hour commute. I know that thing. 419 00:25:11,960 --> 00:25:15,520 Speaker 1: I do it when I sew Yeah. Enclosed are two 420 00:25:15,560 --> 00:25:18,600 Speaker 1: calendars featuring an I P I created back in two eleven. 421 00:25:18,960 --> 00:25:21,480 Speaker 1: I hope you enjoy the many historically charged characters and 422 00:25:21,520 --> 00:25:23,960 Speaker 1: the merry quotations that come with each one. Thank you 423 00:25:24,000 --> 00:25:27,440 Speaker 1: for keeping me saying have a wonderful year, Christina. Oh 424 00:25:27,480 --> 00:25:31,520 Speaker 1: my goodness, Christina, these calendars are like cracked me. They're 425 00:25:31,560 --> 00:25:34,200 Speaker 1: so wondrous. I'm handing them to Tracy. So what These 426 00:25:34,240 --> 00:25:40,760 Speaker 1: are animals? The most beautiful and detailed illustrations UM of 427 00:25:40,840 --> 00:25:45,680 Speaker 1: animals as various historical figures. This is a dog David Bowie. Yes. 428 00:25:46,600 --> 00:25:51,080 Speaker 1: And there's um alten Maker. Yes. They're really amazing and 429 00:25:51,160 --> 00:25:56,400 Speaker 1: her art is mind blowingly beautiful. I cannot be more delighted. 430 00:25:56,400 --> 00:26:01,240 Speaker 1: There's a king tut and came out that is so gorgeous. 431 00:26:01,760 --> 00:26:05,520 Speaker 1: Since I like anything with Egyptian imagery and I am 432 00:26:05,560 --> 00:26:09,040 Speaker 1: a crazy cat lady, seelasically heaven to me. I feel 433 00:26:09,080 --> 00:26:12,240 Speaker 1: like this sloth Josephine Baker is like a special homage 434 00:26:12,280 --> 00:26:15,080 Speaker 1: to previous hosts of the show, which included some big 435 00:26:15,080 --> 00:26:17,960 Speaker 1: time sloth fans. And also they did a podcast on 436 00:26:18,040 --> 00:26:22,000 Speaker 1: jo swim Baker. Yeah, so I just I seriously love, 437 00:26:22,080 --> 00:26:25,400 Speaker 1: love love these so much. Uh. This is one where 438 00:26:25,440 --> 00:26:29,159 Speaker 1: there's also a Mary Smelly, which is Mary Shelley is 439 00:26:29,200 --> 00:26:31,800 Speaker 1: a skunk that is so beautiful I kind of can't 440 00:26:31,840 --> 00:26:36,320 Speaker 1: deal with it. This one has William Shakespeare. It's really 441 00:26:36,359 --> 00:26:39,080 Speaker 1: really wonderful. There is also Teddy Roosevelt as a big 442 00:26:39,160 --> 00:26:43,359 Speaker 1: gray cat, which is perfect. Um. Obviously, Christina, we are 443 00:26:43,400 --> 00:26:46,240 Speaker 1: delighted beyond all measure by this gift. Thank you so much. 444 00:26:46,280 --> 00:26:50,239 Speaker 1: This also perfectly settles my my current quandary of what 445 00:26:50,359 --> 00:26:52,280 Speaker 1: kind of calendar wall calendar I was going to get 446 00:26:52,320 --> 00:26:55,880 Speaker 1: for next year, because I love a calendar, but it's 447 00:26:55,880 --> 00:26:58,640 Speaker 1: hard to decide sometimes. Well, and this is the right 448 00:26:58,680 --> 00:27:02,480 Speaker 1: size to go on the wall by my computer, because 449 00:27:02,520 --> 00:27:06,480 Speaker 1: I have a Hamilton's calendar that I put for the 450 00:27:06,520 --> 00:27:09,320 Speaker 1: big wall calendar but this is good for the adjacent 451 00:27:09,359 --> 00:27:12,840 Speaker 1: to computer and I can then look at Kitty Roosevelt. 452 00:27:13,000 --> 00:27:16,320 Speaker 1: It's the cutest thing. I mean, these are so gorgeous. 453 00:27:16,359 --> 00:27:18,720 Speaker 1: I love, love love them. So we're going slightly bananas 454 00:27:18,720 --> 00:27:23,679 Speaker 1: over here, Christina. We are going to um take some 455 00:27:23,720 --> 00:27:25,399 Speaker 1: pictures of this and make sure they get up on 456 00:27:25,440 --> 00:27:27,879 Speaker 1: social media. Uh. And we thank you so much. What 457 00:27:27,960 --> 00:27:30,199 Speaker 1: a great way to start a new year. Yeah, is 458 00:27:30,240 --> 00:27:34,720 Speaker 1: with a cat as king hut. If you would like 459 00:27:34,760 --> 00:27:36,680 Speaker 1: to write to us about this or any other episode, 460 00:27:36,720 --> 00:27:39,480 Speaker 1: you can do so at History Podcast at how stuffworks 461 00:27:39,480 --> 00:27:41,919 Speaker 1: dot com. You can also find us pretty much everywhere 462 00:27:41,960 --> 00:27:44,760 Speaker 1: on social media as Missed in History. You can visit 463 00:27:44,760 --> 00:27:47,639 Speaker 1: our website, which is missed in History dot com. Sift 464 00:27:47,640 --> 00:27:50,000 Speaker 1: through our archive of all the episodes, look at show 465 00:27:50,040 --> 00:27:52,200 Speaker 1: notes for the episodes Tracy and I have worked on, 466 00:27:52,560 --> 00:27:54,800 Speaker 1: and just see what we've been up to. Uh, we 467 00:27:54,880 --> 00:27:56,879 Speaker 1: hope we do. Come and visit us at missed in 468 00:27:57,000 --> 00:28:04,639 Speaker 1: History dot com. For more on this and thousands of 469 00:28:04,680 --> 00:28:10,040 Speaker 1: other topics, visit how stuff works dot com. M