1 00:00:02,040 --> 00:00:07,840 Speaker 1: Welcome to brain stuff from how stuff works a brain 2 00:00:07,920 --> 00:00:11,360 Speaker 1: stuff it's Christian saga. Sometimes you're right in the middle 3 00:00:11,360 --> 00:00:13,560 Speaker 1: of cleaning up the drain in the shower and you 4 00:00:13,600 --> 00:00:17,280 Speaker 1: start pondering questions like why is my hair color different 5 00:00:17,280 --> 00:00:21,239 Speaker 1: color from my mom's hair or my neighbor's hair or 6 00:00:21,360 --> 00:00:26,479 Speaker 1: my roommates disgusting soggy three foot long wolf tail drain wad? 7 00:00:27,120 --> 00:00:31,240 Speaker 1: What's the real difference between blonde hair, black hair, red hair, 8 00:00:31,320 --> 00:00:35,680 Speaker 1: and everything in between? Well, the main structural ingredient in 9 00:00:35,800 --> 00:00:39,360 Speaker 1: human hair is a protein called keratin. It's what your 10 00:00:39,400 --> 00:00:43,080 Speaker 1: hair and fingernails are made of, but also what's behind 11 00:00:43,120 --> 00:00:48,920 Speaker 1: the silky sheen of wool bear claws and horse hooves. Mmmm. 12 00:00:49,200 --> 00:00:52,479 Speaker 1: Don't you just want to run your fingers through those hooves? 13 00:00:52,479 --> 00:00:55,920 Speaker 1: But keratin on its own is not very colorful, and 14 00:00:56,000 --> 00:00:59,960 Speaker 1: if all humans having our hair was keratin, we'd look 15 00:01:00,120 --> 00:01:04,480 Speaker 1: like eighteenth century French aristocrats in powdered wigs because we'd 16 00:01:04,560 --> 00:01:08,319 Speaker 1: all have the same sort of white, colorless hair. But 17 00:01:08,959 --> 00:01:12,720 Speaker 1: keratin is not the only ingredient in human hair. To 18 00:01:12,760 --> 00:01:15,920 Speaker 1: create natural color, you need to add pigment. This is 19 00:01:15,959 --> 00:01:19,119 Speaker 1: done by cells in the skin called melano sites. These 20 00:01:19,160 --> 00:01:22,560 Speaker 1: melano sites create the natural pigment known as melanin and 21 00:01:23,000 --> 00:01:25,880 Speaker 1: deliver it to the cells that create the keratin for 22 00:01:26,080 --> 00:01:30,160 Speaker 1: your hair, and this melanin comes into varieties you melanin 23 00:01:30,560 --> 00:01:34,640 Speaker 1: and THEO melanin. You melanin is a dark pigment that 24 00:01:34,720 --> 00:01:38,640 Speaker 1: gives hair a brown or black color. THEO melanin is 25 00:01:38,680 --> 00:01:41,800 Speaker 1: a lighter pigment that gives hair a red, orange, or 26 00:01:41,920 --> 00:01:45,520 Speaker 1: yellowish color. Both of these are present in varying degrees. 27 00:01:45,600 --> 00:01:48,200 Speaker 1: A person might have had a little of each, or 28 00:01:48,240 --> 00:01:50,320 Speaker 1: a lot of one and almost none of the other. 29 00:01:50,800 --> 00:01:53,960 Speaker 1: So someone with black or dark brown hair probably has 30 00:01:54,040 --> 00:01:57,160 Speaker 1: a lot of YOU melanin. A red head has a 31 00:01:57,240 --> 00:02:00,640 Speaker 1: lot of THEO melanin, and blonds well they don't have 32 00:02:00,800 --> 00:02:03,720 Speaker 1: very much of either one. So what happens when we 33 00:02:03,760 --> 00:02:07,360 Speaker 1: get older and start to go gray, Well you can 34 00:02:07,400 --> 00:02:11,120 Speaker 1: probably guess. Over time, melanocytes start to die off, and 35 00:02:11,240 --> 00:02:14,760 Speaker 1: any new hair that grows has less pigment, so it 36 00:02:14,840 --> 00:02:18,480 Speaker 1: looks gray or white. But you might be asking what 37 00:02:18,680 --> 00:02:22,560 Speaker 1: determines the you melanin to feel melanin mixture to begin with? 38 00:02:22,680 --> 00:02:26,959 Speaker 1: Who writes that recipe? Well, primarily it's your genes. For example, 39 00:02:27,240 --> 00:02:32,160 Speaker 1: the melano corton one receptor or m c one ur gene. 40 00:02:32,520 --> 00:02:36,240 Speaker 1: When the protein associated with this gene is active in melanocytes, 41 00:02:36,560 --> 00:02:39,440 Speaker 1: it stimulates them to make you melanin, the pigment that 42 00:02:39,480 --> 00:02:42,400 Speaker 1: colors black or brown hair. When m c one r 43 00:02:42,560 --> 00:02:45,400 Speaker 1: is not active in the melano syites cells, they make 44 00:02:45,520 --> 00:02:50,680 Speaker 1: mostly feel melanin instead and hello Weasley's. But the mc 45 00:02:50,919 --> 00:02:54,000 Speaker 1: one our gene is not the only genetic factor that 46 00:02:54,080 --> 00:02:57,639 Speaker 1: controls hair color. Like most of your traits, hair color 47 00:02:57,760 --> 00:03:00,760 Speaker 1: is actually affected by more than one gene attic variable. 48 00:03:01,120 --> 00:03:06,040 Speaker 1: For example, in a study in the journal Natural Genetics 49 00:03:06,240 --> 00:03:10,360 Speaker 1: linked blonde hair in Northern Europeans to a genetic mutation 50 00:03:10,480 --> 00:03:16,079 Speaker 1: in one single nucleotide controlling gene expression in hair follicles. 51 00:03:16,440 --> 00:03:20,680 Speaker 1: They even bred mice with the same tiny mutation, and 52 00:03:20,720 --> 00:03:24,560 Speaker 1: the mice had lighter colored fur than mice without the mutation. 53 00:03:30,680 --> 00:03:32,720 Speaker 1: Check out the brain stuff channel on YouTube, and for 54 00:03:32,760 --> 00:03:35,200 Speaker 1: more on this and thousands of other topics, visit how 55 00:03:35,240 --> 00:03:50,040 Speaker 1: stuff works dot com.