1 00:00:00,080 --> 00:00:04,400 Speaker 1: Joining us now, Christopher Berner, Bristol Myers Squab CEO. Great 2 00:00:04,440 --> 00:00:06,600 Speaker 1: see you, Christopher. Thanks for stopping by and giving us 3 00:00:06,600 --> 00:00:08,959 Speaker 1: some of your time on what I'm sure is a 4 00:00:09,039 --> 00:00:12,400 Speaker 1: busy schedule for you over these few days. Let's talk 5 00:00:12,400 --> 00:00:15,880 Speaker 1: about it to be where you see this business. Let's 6 00:00:15,880 --> 00:00:19,440 Speaker 1: talk about where you see this business. You've changed, you 7 00:00:19,680 --> 00:00:23,040 Speaker 1: have come in, you've delivered a flurry of deals. You 8 00:00:23,120 --> 00:00:25,759 Speaker 1: in the process of fixing Bristol Myers. 9 00:00:26,800 --> 00:00:28,320 Speaker 2: Well, first of all, it's great to be here. Thank 10 00:00:28,320 --> 00:00:30,479 Speaker 2: you for the time. Look, I'm incredibly excited to be 11 00:00:30,560 --> 00:00:32,879 Speaker 2: taking over as CEO of this great company. 12 00:00:33,280 --> 00:00:34,879 Speaker 3: Our business is in a bit of a transition. 13 00:00:34,920 --> 00:00:37,479 Speaker 2: We have a number of products that have gone off patent, 14 00:00:37,520 --> 00:00:40,680 Speaker 2: but we're replacing them with a younger, exciting portfolio, a 15 00:00:40,760 --> 00:00:43,279 Speaker 2: portfolio that we think is going to drive long term 16 00:00:43,320 --> 00:00:46,080 Speaker 2: sustainable growth for the company. And so you know, look, 17 00:00:46,120 --> 00:00:49,320 Speaker 2: this business is one that continues to be dynamic. Business 18 00:00:49,360 --> 00:00:52,360 Speaker 2: development has always been part of our history, and the 19 00:00:52,400 --> 00:00:54,840 Speaker 2: deals that we've done over the last few months makes sense. 20 00:00:55,160 --> 00:00:59,200 Speaker 2: The Karuna deal accelerates our entree or re entree into neuroscience. 21 00:00:59,240 --> 00:01:04,400 Speaker 2: We extend ended our leadership position with additional platforms and oncology. 22 00:01:04,520 --> 00:01:06,520 Speaker 2: So we're excited about the deals that we've done and 23 00:01:06,560 --> 00:01:08,160 Speaker 2: we think they're going to contribute to the growth of 24 00:01:08,160 --> 00:01:09,640 Speaker 2: the company in the back half of the decade. 25 00:01:09,840 --> 00:01:11,800 Speaker 4: Part of the reason why we love the David Morgant 26 00:01:11,800 --> 00:01:14,720 Speaker 4: Healthcare Conference is like this is where also deals get done. 27 00:01:14,959 --> 00:01:16,280 Speaker 3: This is sort of the speed. 28 00:01:16,040 --> 00:01:19,560 Speaker 4: Dating, as Guy was referring to it, is that happening 29 00:01:19,600 --> 00:01:20,000 Speaker 4: this year. 30 00:01:21,040 --> 00:01:22,920 Speaker 2: Well, we're seeing a lot of companies. You know, the 31 00:01:23,000 --> 00:01:27,520 Speaker 2: innovation in this space has been absolutely spectacular, and again 32 00:01:27,600 --> 00:01:30,600 Speaker 2: this year we're seeing a lot of really incredible innovation 33 00:01:30,720 --> 00:01:33,800 Speaker 2: and fortunately for us, we've been active in this space. 34 00:01:33,840 --> 00:01:37,039 Speaker 2: You know, business development was something that we've done historically. 35 00:01:37,120 --> 00:01:38,479 Speaker 3: We brought in great products like. 36 00:01:38,400 --> 00:01:43,560 Speaker 2: Avdivo and Camzios in cardiovascular disease via business development. And 37 00:01:43,640 --> 00:01:46,160 Speaker 2: this year, of course, we've done a few deals. We 38 00:01:46,200 --> 00:01:50,040 Speaker 2: did the Karuna deal, which again accelerates us into neuroscience. 39 00:01:50,160 --> 00:01:53,919 Speaker 2: We have gained access to probably the fastest growing platform 40 00:01:54,120 --> 00:01:57,640 Speaker 2: in oncology in radio pharmaceuticals with a deal with a 41 00:01:57,680 --> 00:02:01,560 Speaker 2: company called Raise Bio. Incredibly excited about that opportunity, and 42 00:02:01,600 --> 00:02:03,960 Speaker 2: we're going to continue to have business development be part 43 00:02:04,000 --> 00:02:06,040 Speaker 2: of how we think about capital allocation. 44 00:02:07,760 --> 00:02:11,720 Speaker 1: Because the market has to be concerned about the company 45 00:02:11,840 --> 00:02:14,760 Speaker 1: and its pipeline. It's business in the latter half of 46 00:02:14,800 --> 00:02:18,160 Speaker 1: this decade, it's not now, it's further down the road. 47 00:02:18,160 --> 00:02:20,000 Speaker 1: As you say, you've got a bunch of things coming 48 00:02:20,000 --> 00:02:23,720 Speaker 1: off patents. Are the deals that you're doing validating that concern? 49 00:02:24,919 --> 00:02:27,320 Speaker 2: Well, Look, I mean the first priority that we have 50 00:02:27,440 --> 00:02:29,600 Speaker 2: as a company is to focus on what is a 51 00:02:29,600 --> 00:02:31,520 Speaker 2: absolutely spectacular. 52 00:02:30,919 --> 00:02:32,200 Speaker 3: Pipeline that we have Internally. 53 00:02:32,240 --> 00:02:36,200 Speaker 2: We have probably more catalysts from our internal organic pipeline 54 00:02:36,240 --> 00:02:38,560 Speaker 2: than I think we've ever had. We have the potential 55 00:02:38,880 --> 00:02:42,280 Speaker 2: to launch over sixteen new medicines between now in the end. 56 00:02:42,160 --> 00:02:42,760 Speaker 3: Of the decade. 57 00:02:43,200 --> 00:02:46,360 Speaker 2: Just since the last JPM Morgan, we've doubled the number 58 00:02:46,400 --> 00:02:48,760 Speaker 2: of late stage assets we have. So we have a 59 00:02:48,880 --> 00:02:52,160 Speaker 2: very very good pipeline. You know, Historically, as I've said, 60 00:02:52,200 --> 00:02:55,320 Speaker 2: business development has been part of how we source innovation. 61 00:02:55,440 --> 00:02:56,560 Speaker 3: It's going to continue to be. 62 00:02:57,240 --> 00:03:01,000 Speaker 2: But I wouldn't confuse that with the lying dynamics that 63 00:03:01,040 --> 00:03:03,240 Speaker 2: we have in our portfolio, which is a very strong 64 00:03:03,320 --> 00:03:04,240 Speaker 2: portfolio today. 65 00:03:04,360 --> 00:03:06,760 Speaker 4: Okay, so we're not reading into what you think about 66 00:03:06,760 --> 00:03:08,840 Speaker 4: the current portfolio because of the flurry of M and 67 00:03:08,880 --> 00:03:11,880 Speaker 4: A not at all. Okay, So it is the M 68 00:03:11,919 --> 00:03:12,800 Speaker 4: and A stuff done for you. 69 00:03:14,080 --> 00:03:16,440 Speaker 2: Well, as I said, business development is going to be 70 00:03:16,800 --> 00:03:19,200 Speaker 2: part of the way we think about capital allocation. We've 71 00:03:19,200 --> 00:03:22,080 Speaker 2: been able to do business to development historically while also 72 00:03:22,440 --> 00:03:25,880 Speaker 2: committing to return capital to shareholders. We've returned over thirty 73 00:03:25,880 --> 00:03:29,440 Speaker 2: billion dollars to shareholders over the last three years. We've 74 00:03:29,520 --> 00:03:32,359 Speaker 2: maintained a commitment to the dividend. We've raised the dividend 75 00:03:32,639 --> 00:03:35,560 Speaker 2: consecutively fifteen years in a row. But we're going to 76 00:03:35,560 --> 00:03:38,600 Speaker 2: continue to source innovation externally, add it to what is 77 00:03:38,640 --> 00:03:41,320 Speaker 2: a very robust pipeline that we have internally. 78 00:03:43,200 --> 00:03:46,560 Speaker 1: GLP ones. Are you interested? What do you think? A 79 00:03:47,160 --> 00:03:50,400 Speaker 1: lot of noise in that space? Last year, obesity has 80 00:03:50,400 --> 00:03:54,360 Speaker 1: been the big story for the healthcaret sect. Is it 81 00:03:54,400 --> 00:03:56,000 Speaker 1: okay not to be in that space. 82 00:03:56,800 --> 00:04:00,560 Speaker 2: Well, we're not in the GLP one or metal space, 83 00:04:00,600 --> 00:04:01,760 Speaker 2: but let me tell you where we are. 84 00:04:01,920 --> 00:04:04,160 Speaker 3: We are in four very. 85 00:04:03,960 --> 00:04:06,680 Speaker 2: Commercially attractive and growing therapeutic areas today. We have a 86 00:04:06,720 --> 00:04:10,680 Speaker 2: large presence, for example, in cardiovascular disease, in oncology, we're 87 00:04:10,720 --> 00:04:13,800 Speaker 2: growing our business in immunology, and as I said, we're 88 00:04:13,840 --> 00:04:17,600 Speaker 2: reaccelerating in a very active area of neuroscience. So these 89 00:04:17,600 --> 00:04:20,680 Speaker 2: are important areas, but above and beyond the individual assets 90 00:04:20,680 --> 00:04:23,200 Speaker 2: that we have in those therapeutic areas, we're investing in 91 00:04:23,240 --> 00:04:26,920 Speaker 2: platforms that are incredibly exciting. We're particularly excited about our 92 00:04:26,920 --> 00:04:29,800 Speaker 2: cell therapy platform, for example, which has the potential to 93 00:04:29,800 --> 00:04:33,360 Speaker 2: move from oncology into immunology and be a very large 94 00:04:33,400 --> 00:04:35,360 Speaker 2: contributor to growth in the back half of the decade. 95 00:04:36,640 --> 00:04:41,560 Speaker 1: Because how do you think though the obesity story is 96 00:04:41,600 --> 00:04:44,719 Speaker 1: going to develop, It's not going to happen in isolation. 97 00:04:45,400 --> 00:04:50,680 Speaker 1: What happens with people's waistlines, their metabolic rates has an 98 00:04:50,720 --> 00:04:54,720 Speaker 1: impact on so much else within the healthcare sector. What 99 00:04:54,760 --> 00:04:57,080 Speaker 1: do you think the ripple effects of this are going 100 00:04:57,120 --> 00:04:58,480 Speaker 1: to be and what are those going to look like? 101 00:04:58,560 --> 00:05:02,040 Speaker 1: And is it that kind of second derivative effects into 102 00:05:02,080 --> 00:05:05,599 Speaker 1: cardiovascular into other areas of the healthcare sector that I 103 00:05:05,600 --> 00:05:07,680 Speaker 1: think could prove to be just as interesting. 104 00:05:08,520 --> 00:05:09,400 Speaker 3: Well, I think you're right. 105 00:05:09,440 --> 00:05:12,160 Speaker 2: I think all aspects of healthcare in some way related, 106 00:05:12,200 --> 00:05:14,680 Speaker 2: and so I think as you start to see changes, 107 00:05:14,720 --> 00:05:18,400 Speaker 2: for example, in metabolic disease, it certainly has broader implications. 108 00:05:18,400 --> 00:05:21,360 Speaker 2: From our standpoint, we're watching it because of the focus 109 00:05:21,480 --> 00:05:24,080 Speaker 2: in cardiovascular disease that we have. You know, we're a 110 00:05:24,160 --> 00:05:27,080 Speaker 2: leader today in cardiovascular disease. We have a very big 111 00:05:27,120 --> 00:05:30,719 Speaker 2: business in cardiomyopathies with a drug that we acquired through 112 00:05:30,760 --> 00:05:33,920 Speaker 2: business development called Camzios that's doing very well with long 113 00:05:34,000 --> 00:05:37,280 Speaker 2: term potential. And we're a leader in thrombosis with eloquist today, 114 00:05:37,320 --> 00:05:40,799 Speaker 2: and we've got an exciting portfolio in thrombosis to maintain 115 00:05:40,839 --> 00:05:41,800 Speaker 2: that leadership position. 116 00:05:41,839 --> 00:05:43,080 Speaker 3: So we're watching it very closely. 117 00:05:43,640 --> 00:05:45,080 Speaker 4: Is there any point where you think you may want 118 00:05:45,120 --> 00:05:47,800 Speaker 4: to get into that space, like is there efficacy or 119 00:05:47,880 --> 00:05:51,120 Speaker 4: take up or even Medicare or Medicaid covering it that 120 00:05:51,160 --> 00:05:53,040 Speaker 4: would sort of maybe trigger you guys to think of 121 00:05:53,080 --> 00:05:53,560 Speaker 4: it differently. 122 00:05:54,440 --> 00:05:57,240 Speaker 2: Well, we look at our therapeutic areas in a very 123 00:05:57,320 --> 00:05:59,880 Speaker 2: dynamic way. We're not sort of dogmatic in the areas 124 00:05:59,880 --> 00:06:03,520 Speaker 2: that we're in today. For example, we were in neuroscience 125 00:06:03,560 --> 00:06:04,360 Speaker 2: many years ago with. 126 00:06:04,360 --> 00:06:05,440 Speaker 3: A drug called a bilify. 127 00:06:05,480 --> 00:06:07,640 Speaker 2: It was one of the largest drugs in the world, 128 00:06:07,760 --> 00:06:10,040 Speaker 2: is still being used heavily in that space. We've decided 129 00:06:10,120 --> 00:06:12,640 Speaker 2: to get back into that space now because we're excited 130 00:06:12,680 --> 00:06:15,680 Speaker 2: about our early portfolio in Alzheimer's disease, and of course 131 00:06:15,760 --> 00:06:18,800 Speaker 2: now with Karuna we've made the move into neurosyche, which 132 00:06:18,800 --> 00:06:23,240 Speaker 2: has a nice adjacency to neurodegeneration. So we're always looking 133 00:06:23,279 --> 00:06:26,200 Speaker 2: for where there are opportunities. The key thing we focus on, though, 134 00:06:26,240 --> 00:06:29,640 Speaker 2: is where do we find really exciting science and where 135 00:06:29,680 --> 00:06:32,080 Speaker 2: is it likely that Bristol myersquipt can be a leader. 136 00:06:32,120 --> 00:06:33,240 Speaker 3: That's what we focus on. 137 00:06:34,600 --> 00:06:37,040 Speaker 1: So Christopher paying me a picture. You're at the JP 138 00:06:37,160 --> 00:06:39,920 Speaker 1: Morgan conference. You're talking to a whole bunch of people, 139 00:06:39,920 --> 00:06:42,359 Speaker 1: You're bumping into a whole lot of people. What are 140 00:06:42,400 --> 00:06:46,880 Speaker 1: people talking about? Is what is happening with JLP ones, 141 00:06:47,000 --> 00:06:50,320 Speaker 1: is it the story of last year? What's happening with 142 00:06:50,360 --> 00:06:52,719 Speaker 1: the election coming up in the United States and elsewhere 143 00:06:52,720 --> 00:06:55,839 Speaker 1: around the world. What are people talking about at that conference, 144 00:06:55,839 --> 00:06:57,279 Speaker 1: because that's going to give us a good idea of 145 00:06:57,320 --> 00:06:59,320 Speaker 1: what twenty four is going to be looking like rather 146 00:06:59,320 --> 00:06:59,960 Speaker 1: than twenty three. 147 00:07:00,880 --> 00:07:02,240 Speaker 2: Well, I think there are a couple of things people 148 00:07:02,240 --> 00:07:04,240 Speaker 2: are talking about. I think generally in the industry, there's 149 00:07:04,279 --> 00:07:07,320 Speaker 2: a lot of discussion, of course about the therapeutic areas 150 00:07:07,320 --> 00:07:09,680 Speaker 2: that you just reference. There's also a lot of excitement 151 00:07:09,760 --> 00:07:13,320 Speaker 2: about innovation in this space. You're seeing a pickup in 152 00:07:13,360 --> 00:07:15,760 Speaker 2: some of the discussions around business development. Of course, we 153 00:07:15,760 --> 00:07:18,160 Speaker 2: were active in that at the end of last year. 154 00:07:18,320 --> 00:07:21,440 Speaker 2: There's a lot of exciting innovation being discussed at this conference. 155 00:07:21,600 --> 00:07:24,160 Speaker 2: Of course, we're focused on how do we tell our 156 00:07:24,240 --> 00:07:26,440 Speaker 2: story about how this company is going to evolve to 157 00:07:26,480 --> 00:07:29,160 Speaker 2: be one of the fastest growing companies in the industry 158 00:07:29,160 --> 00:07:30,920 Speaker 2: by the end of the decade. There's a lot of 159 00:07:30,960 --> 00:07:33,400 Speaker 2: interest in what does that business look like over the 160 00:07:33,440 --> 00:07:34,480 Speaker 2: course of the decade. 161 00:07:34,760 --> 00:07:36,440 Speaker 3: So those are the conversations that we're having. 162 00:07:36,520 --> 00:07:39,760 Speaker 2: But there is a lot of excitement about the possibilities 163 00:07:39,800 --> 00:07:43,600 Speaker 2: for truly innovative medicines in this space, and of course 164 00:07:43,640 --> 00:07:46,920 Speaker 2: Bristol Myers Squib is at the center of that innovation ecosystem. 165 00:07:47,440 --> 00:07:49,040 Speaker 4: Christopher, this might be more of a question that you 166 00:07:49,120 --> 00:07:51,600 Speaker 4: and your CFO have, but on a macro level, for 167 00:07:51,640 --> 00:07:53,560 Speaker 4: the markets, we talk a lot about what central banks 168 00:07:53,600 --> 00:07:55,920 Speaker 4: are going to do in cutting rates. If the Better 169 00:07:56,000 --> 00:07:59,000 Speaker 4: Reserve cuts rates, does that do anything for you guys, 170 00:07:59,000 --> 00:08:01,160 Speaker 4: Does that help in any way? Is it jumpstart M 171 00:08:01,200 --> 00:08:02,880 Speaker 4: and A in any way whatsoever? Because this is a 172 00:08:02,880 --> 00:08:05,120 Speaker 4: markedly different environment today than if you guys had this 173 00:08:05,120 --> 00:08:06,240 Speaker 4: conference six months ago. 174 00:08:06,960 --> 00:08:09,080 Speaker 2: Well, listen, the way we think about m and as 175 00:08:09,120 --> 00:08:11,320 Speaker 2: first and foremost doesn't make strategic sense for us to 176 00:08:11,320 --> 00:08:13,720 Speaker 2: be involved in it. And then are there deals that 177 00:08:13,800 --> 00:08:16,640 Speaker 2: do a few things, build depth and therapeutic areas we're in, 178 00:08:16,760 --> 00:08:18,600 Speaker 2: or expand in areas that we want to go into 179 00:08:18,640 --> 00:08:21,560 Speaker 2: where we find the science super attractive and exciting. And 180 00:08:21,560 --> 00:08:23,640 Speaker 2: then of course the deals have to make financial sense. 181 00:08:23,800 --> 00:08:26,120 Speaker 2: And all of that is in some ways independent of 182 00:08:26,160 --> 00:08:29,160 Speaker 2: what's happening in the broader macro environment. We're very fortunate 183 00:08:29,160 --> 00:08:31,760 Speaker 2: at BMS to have a very strong business. It's a 184 00:08:31,880 --> 00:08:34,920 Speaker 2: very strong cash generating business. We certainly have the financial 185 00:08:34,960 --> 00:08:37,800 Speaker 2: flexibility and horsepower to do the deals we want to do, 186 00:08:38,080 --> 00:08:42,319 Speaker 2: really to some extent, irrespective of these broader macroeconomic factors. 187 00:08:42,440 --> 00:08:45,280 Speaker 4: Say, with macroeconomics, for just one more moment, Christopher, what's 188 00:08:45,280 --> 00:08:48,160 Speaker 4: your hiring situation, Like, how has your labor force evolved 189 00:08:48,160 --> 00:08:50,160 Speaker 4: and kind of what's your outlook on that end for 190 00:08:50,240 --> 00:08:50,640 Speaker 4: this year. 191 00:08:51,520 --> 00:08:54,160 Speaker 2: Well, our labor force continues to evolve with the evolution 192 00:08:54,280 --> 00:08:56,559 Speaker 2: of our business. So for example, we've just done a 193 00:08:56,640 --> 00:08:59,400 Speaker 2: deal to re enter neuroscience. That's a space we've not 194 00:08:59,480 --> 00:09:01,400 Speaker 2: been in for some amount of time. We're going to 195 00:09:01,440 --> 00:09:02,920 Speaker 2: be building that infrastructure. 196 00:09:03,000 --> 00:09:03,520 Speaker 3: We've got a. 197 00:09:03,440 --> 00:09:06,880 Speaker 2: PADUFA date for car Xt, which is the lead asset 198 00:09:06,920 --> 00:09:09,000 Speaker 2: we got from Karuna in September, so we got to 199 00:09:09,000 --> 00:09:11,800 Speaker 2: build that team. I would say across the remainder of 200 00:09:11,840 --> 00:09:13,680 Speaker 2: the business that labor force. 201 00:09:13,520 --> 00:09:15,719 Speaker 3: Is relatively stable right now, but we're going. 202 00:09:15,720 --> 00:09:18,760 Speaker 2: To always evolve the organization to align to where we're 203 00:09:18,800 --> 00:09:19,920 Speaker 2: focused as a company. 204 00:09:20,400 --> 00:09:21,440 Speaker 3: All right, Christopher, thanks a lot. 205 00:09:21,440 --> 00:09:23,480 Speaker 4: We appreciate you coming over and giving us so much 206 00:09:23,480 --> 00:09:25,880 Speaker 4: of your time. Christopher Berner or Bristol Maya Squipt