1 00:00:03,840 --> 00:00:05,120 Speaker 1: Hello Sunshine. 2 00:00:05,320 --> 00:00:08,360 Speaker 2: Hey fam Today on the bright Side, it's Wellness Wednesday, 3 00:00:08,400 --> 00:00:11,400 Speaker 2: and Professor Sarah Berry is here to share the research 4 00:00:11,440 --> 00:00:15,000 Speaker 2: backtips on how you can minimize your menopause symptoms by 5 00:00:15,000 --> 00:00:19,079 Speaker 2: simply changing the way you eat. It's Wednesday, November twenty seventh. 6 00:00:19,239 --> 00:00:20,720 Speaker 2: I'm Simone Boyce, I'm. 7 00:00:20,640 --> 00:00:23,840 Speaker 3: Danielle Robe and this is The bright Side from Hello Sunshine, 8 00:00:24,160 --> 00:00:27,040 Speaker 3: a daily show where we come together to share women's stories, 9 00:00:27,400 --> 00:00:31,480 Speaker 3: to laugh, learn and brighten your day. Today's Wellness Wednesday 10 00:00:31,520 --> 00:00:32,760 Speaker 3: is presented by Cooligard. 11 00:00:36,520 --> 00:00:38,680 Speaker 2: Welcome to the bright Side, y'all. We've got to kick 12 00:00:38,720 --> 00:00:41,880 Speaker 2: off today's show with a very special announcement, the December 13 00:00:41,920 --> 00:00:43,680 Speaker 2: pick for Reese's book Club. 14 00:00:44,360 --> 00:00:50,919 Speaker 3: I think that deserves a sound effects, Simone, Okay, Well, 15 00:00:50,960 --> 00:00:54,680 Speaker 3: this December we'll be reading City of night Birds by 16 00:00:54,680 --> 00:00:58,400 Speaker 3: the Fantastic Jew Hey Kim. Her book is out now 17 00:00:58,440 --> 00:01:01,400 Speaker 3: and it's a perfect companion for all of your holiday travels. 18 00:01:01,440 --> 00:01:04,600 Speaker 3: I promise we are so excited because we're actually going 19 00:01:04,680 --> 00:01:07,120 Speaker 3: to be having her on the show this December as well. 20 00:01:07,560 --> 00:01:11,039 Speaker 2: I've already got my copy. I cannot wait to start reading. Okay, 21 00:01:11,680 --> 00:01:15,000 Speaker 2: now let's talk about today Today's welles Wednesday, and we're 22 00:01:15,040 --> 00:01:18,959 Speaker 2: talking to Professor Sarah Berry all about menopause. But today's 23 00:01:18,959 --> 00:01:20,720 Speaker 2: conversation is going to be a little different. You know, 24 00:01:20,760 --> 00:01:23,560 Speaker 2: we've talked about menopause on the show before, but we're 25 00:01:23,560 --> 00:01:26,680 Speaker 2: not just talking about the usual symptoms or the changes 26 00:01:26,720 --> 00:01:29,720 Speaker 2: we might expect. Today, we're talking about what you put 27 00:01:29,760 --> 00:01:31,600 Speaker 2: at the end of your fork and how it can 28 00:01:31,640 --> 00:01:33,120 Speaker 2: impact your menopausal health. 29 00:01:33,560 --> 00:01:37,520 Speaker 3: Oh, I'm so excited for this conversation because we've had 30 00:01:37,560 --> 00:01:40,640 Speaker 3: the pleasure of talking to doctors and experts about menopause 31 00:01:40,680 --> 00:01:44,399 Speaker 3: on the show before, sure, and we've learned some surprising symptoms. 32 00:01:44,440 --> 00:01:47,560 Speaker 3: We've learned about the importance of exercise and what we 33 00:01:47,600 --> 00:01:50,919 Speaker 3: can expect as our bodies change, which is all super 34 00:01:50,920 --> 00:01:54,840 Speaker 3: important because I think the dialogue about menopause has finally 35 00:01:55,040 --> 00:01:59,680 Speaker 3: been opened up in American society. But today we're giving 36 00:01:59,720 --> 00:02:04,840 Speaker 3: you the researched backed tips on how nutrition, what we eat, 37 00:02:05,160 --> 00:02:08,400 Speaker 3: when we eat, and even how often we eat can 38 00:02:08,440 --> 00:02:12,280 Speaker 3: have a major impact on our lives. So Professor Barry 39 00:02:12,360 --> 00:02:16,600 Speaker 3: has conducted nutrition research trials for more than twenty years. 40 00:02:17,040 --> 00:02:20,040 Speaker 3: She's a professor at King's College, London and chief scientists 41 00:02:20,040 --> 00:02:22,880 Speaker 3: at a nutrition science startup that helps users reach their 42 00:02:22,880 --> 00:02:27,160 Speaker 3: health goals with personalized recommendations. And like you said Simone 43 00:02:27,160 --> 00:02:29,560 Speaker 3: about the ends of our forks, I think sometimes the 44 00:02:29,560 --> 00:02:33,200 Speaker 3: best medicine, so to speak, is our nutrition. So I'm 45 00:02:33,200 --> 00:02:34,680 Speaker 3: really excited for this conversation. 46 00:02:35,919 --> 00:02:38,560 Speaker 2: Let's bring her in. Professor Sarah Berry, Welcome to the 47 00:02:38,560 --> 00:02:39,919 Speaker 2: bright Side. 48 00:02:40,040 --> 00:02:41,880 Speaker 4: Thanks for having me on the bright side. 49 00:02:42,120 --> 00:02:45,880 Speaker 3: Now, you've recently published the largest ever study on the 50 00:02:45,919 --> 00:02:51,200 Speaker 3: impact of diet on menopause symptoms. I'm so curious what 51 00:02:51,320 --> 00:02:54,680 Speaker 3: symptoms you were tracking, what you were looking to understand. 52 00:02:54,840 --> 00:02:56,040 Speaker 1: Tell us about this study. 53 00:02:57,560 --> 00:03:01,000 Speaker 4: Yeah, so in ah Zoe, you credic cohorts. So this 54 00:03:01,200 --> 00:03:05,440 Speaker 4: huge group we had over seventy thousand individuals who were 55 00:03:05,480 --> 00:03:09,080 Speaker 4: either pery or postmenopause or women. We asked them to 56 00:03:09,120 --> 00:03:12,200 Speaker 4: tell us about the symptoms they're experiencing, but also grade 57 00:03:12,240 --> 00:03:14,880 Speaker 4: them each symptom on a scale of zero to five 58 00:03:15,240 --> 00:03:17,640 Speaker 4: as to how much they impacted their quality of life. 59 00:03:18,080 --> 00:03:21,160 Speaker 4: And I think what was most interesting about this research 60 00:03:21,520 --> 00:03:25,960 Speaker 4: was just seeing how prevalent the symptoms were. We saw, 61 00:03:26,080 --> 00:03:30,639 Speaker 4: for example, that eighty percent of women were experiencing sleep disturbances, 62 00:03:30,720 --> 00:03:36,120 Speaker 4: brain fog, memory loss, mood changes, depression, anxiety. In more 63 00:03:36,160 --> 00:03:40,160 Speaker 4: than eighty percent of women, and that sixty six percent 64 00:03:40,200 --> 00:03:44,320 Speaker 4: of women had twelve or more symptoms. You know, that's huge, 65 00:03:44,600 --> 00:03:46,760 Speaker 4: and you know many of them were reporting these to 66 00:03:46,760 --> 00:03:49,240 Speaker 4: have a really big impact on their quality of life. 67 00:03:49,360 --> 00:03:50,880 Speaker 4: And I think one of the things that I found 68 00:03:51,080 --> 00:03:54,240 Speaker 4: most interesting doing this research is I came in very 69 00:03:54,280 --> 00:03:57,800 Speaker 4: much thinking, Okay, menopause is very much about hot flashes 70 00:03:57,840 --> 00:04:00,680 Speaker 4: and night sweats. You know, all of the search around 71 00:04:00,720 --> 00:04:03,760 Speaker 4: diet or lifestyle modification has always been, okay, how does 72 00:04:03,800 --> 00:04:06,480 Speaker 4: this impact what we call the phasomotor symptoms, So those 73 00:04:06,520 --> 00:04:09,840 Speaker 4: symptoms related to blood vessel function, such as night sweats, 74 00:04:09,840 --> 00:04:13,880 Speaker 4: such as hot flushes, but actually those were the least prevalent, 75 00:04:14,440 --> 00:04:16,680 Speaker 4: and we found that it was only about thirty to 76 00:04:16,680 --> 00:04:19,520 Speaker 4: forty percent of people actually had any type of hot 77 00:04:19,560 --> 00:04:22,360 Speaker 4: flush or any type of kind of night swere it 78 00:04:22,400 --> 00:04:25,520 Speaker 4: was all of these other kind of psychological symptoms that 79 00:04:25,560 --> 00:04:28,680 Speaker 4: we know have such wide reaching impacts on other areas 80 00:04:28,680 --> 00:04:32,120 Speaker 4: of people's lives that were most prevalent, which is really interesting. 81 00:04:33,160 --> 00:04:36,520 Speaker 2: In addition to looking at menopause symptoms, this study also 82 00:04:36,640 --> 00:04:40,320 Speaker 2: looked at how symptoms and diet are linked. What did 83 00:04:40,360 --> 00:04:42,640 Speaker 2: you determine by tracking symptoms and diet. 84 00:04:43,720 --> 00:04:46,159 Speaker 4: So I think what I found most surprising is just 85 00:04:46,360 --> 00:04:51,120 Speaker 4: how closely associated diet was with symptom prevalence of symptom burden. 86 00:04:51,360 --> 00:04:54,839 Speaker 4: And what we found is really close association with people's 87 00:04:54,920 --> 00:04:58,840 Speaker 4: diet quality, so their oval helpfulness of the diet and 88 00:04:58,880 --> 00:05:02,440 Speaker 4: their prevalence of symptoms. And for every kind of step 89 00:05:02,480 --> 00:05:06,479 Speaker 4: wise improvement that people were showing in their diet, there 90 00:05:06,560 --> 00:05:10,400 Speaker 4: is a reduction in symptoms. What we also saw was 91 00:05:10,480 --> 00:05:15,960 Speaker 4: that people's body weight and their BMI, in particular their 92 00:05:15,960 --> 00:05:19,040 Speaker 4: body mass index was also playing a role in this. 93 00:05:19,560 --> 00:05:22,479 Speaker 4: So people who had a higher BMI who were living 94 00:05:22,520 --> 00:05:26,680 Speaker 4: with obesity or overweight had a lot higher prevalence of symptoms, 95 00:05:27,240 --> 00:05:32,280 Speaker 4: and that changing diet reduced symptoms, but also changing diet 96 00:05:32,279 --> 00:05:36,159 Speaker 4: where modified body weight was also reducing symptoms, So I 97 00:05:36,160 --> 00:05:38,719 Speaker 4: think that was really interesting. And what we found is 98 00:05:38,760 --> 00:05:42,640 Speaker 4: those that were more adherent to a healthier diet had 99 00:05:42,680 --> 00:05:47,119 Speaker 4: the biggest improvements in the menopause symptoms. 100 00:05:47,160 --> 00:05:47,960 Speaker 1: So interesting. 101 00:05:49,600 --> 00:05:53,400 Speaker 3: You've described menopause as a time of major metabolic upheaval. 102 00:05:54,480 --> 00:05:59,600 Speaker 3: How does menopause affect our metabolism and does it actually 103 00:05:59,600 --> 00:06:01,400 Speaker 3: as probably the other question. 104 00:06:01,839 --> 00:06:04,400 Speaker 4: Yeah, So I think when we think about menopause. So 105 00:06:04,440 --> 00:06:07,039 Speaker 4: we need to think about it in two areas. We 106 00:06:07,080 --> 00:06:09,520 Speaker 4: need to think about it in the areas that we've 107 00:06:09,520 --> 00:06:11,960 Speaker 4: just been talking about. So it's symptoms. But what we 108 00:06:12,080 --> 00:06:16,839 Speaker 4: also know is that menopause impacts our health and disease risk. 109 00:06:17,400 --> 00:06:22,400 Speaker 4: So we also know that it impacts many many intermediary 110 00:06:22,800 --> 00:06:26,720 Speaker 4: risk factors associated with chronic diseases. And so by this 111 00:06:26,800 --> 00:06:35,040 Speaker 4: I mean blood pressure, insert sensitivity, blood cholesterol, inflammation, and 112 00:06:35,120 --> 00:06:37,640 Speaker 4: so many other factors that we know are related to 113 00:06:37,880 --> 00:06:41,440 Speaker 4: chronic diseases. And we recently published some research where we 114 00:06:41,440 --> 00:06:44,719 Speaker 4: were looking at all of these risk factors as we 115 00:06:44,839 --> 00:06:48,279 Speaker 4: call them, and we were looking at all different ages 116 00:06:48,320 --> 00:06:51,600 Speaker 4: and males of females and according to menopausal status. And 117 00:06:51,640 --> 00:06:56,120 Speaker 4: what we see is that in premenopausally, women are doing 118 00:06:56,120 --> 00:06:59,040 Speaker 4: a lot better than men. Women have lower blood pressure, 119 00:06:59,040 --> 00:07:02,719 Speaker 4: lower levels of inflamma, better in slid sensitivity, lower adiprocity, 120 00:07:02,880 --> 00:07:06,159 Speaker 4: so less fatter around the waist, lower blood cholesterol, etc. 121 00:07:07,360 --> 00:07:12,080 Speaker 4: Soon as the women hit the postmenopausal phase, suddenly these 122 00:07:12,120 --> 00:07:14,880 Speaker 4: all go up, and suddenly they even in the case 123 00:07:14,880 --> 00:07:17,560 Speaker 4: of blood pressure, for example, get worse than men. So 124 00:07:17,560 --> 00:07:21,440 Speaker 4: suddenly women's risk of disease, where before they were quite 125 00:07:21,440 --> 00:07:26,040 Speaker 4: protected because of estrogen suddenly changes and so does how 126 00:07:26,080 --> 00:07:29,520 Speaker 4: they metabolize their food. And so this is why I 127 00:07:29,560 --> 00:07:32,160 Speaker 4: think we need to be a little bit more mindful, 128 00:07:32,600 --> 00:07:36,400 Speaker 4: not obsessed, but more mindful when you're peri and postmenopausal 129 00:07:36,520 --> 00:07:41,160 Speaker 4: about the foods that we're eating, not just for symptom prevention, 130 00:07:41,680 --> 00:07:45,520 Speaker 4: but also in order to prevent that big increase in 131 00:07:45,680 --> 00:07:49,040 Speaker 4: risk that we see once you start the perimenopause transition. 132 00:07:50,360 --> 00:07:52,400 Speaker 2: As I was listening to you speak, I was wondering 133 00:07:52,440 --> 00:07:54,360 Speaker 2: about all the different diets that are out there. The 134 00:07:54,400 --> 00:07:59,200 Speaker 2: carnivore diet, ancestral diet, Mediterranean diet. Are any of these 135 00:07:59,280 --> 00:08:02,640 Speaker 2: trendy diet it's beneficial to our menopausal bodies. 136 00:08:04,720 --> 00:08:07,800 Speaker 4: So a lot of the more popular or new diets 137 00:08:07,840 --> 00:08:11,000 Speaker 4: haven't been researched in relation to menopause. There's actually very 138 00:08:11,000 --> 00:08:14,680 Speaker 4: little research looking at whole dietary patterns. What we do 139 00:08:14,800 --> 00:08:17,000 Speaker 4: know is that there are lots of studies looking at 140 00:08:17,040 --> 00:08:23,080 Speaker 4: individual supplements, individual foods, individual nutrients and looking at how 141 00:08:23,120 --> 00:08:26,440 Speaker 4: they impact menopause or symptoms. But the sum of that 142 00:08:26,560 --> 00:08:31,560 Speaker 4: evidence is really inconsistent, partly because small numbers of participants 143 00:08:31,560 --> 00:08:35,640 Speaker 4: have been recruited, that there's such variability in people's symptoms, 144 00:08:36,000 --> 00:08:39,000 Speaker 4: that people symptoms vary day to day. It does mean 145 00:08:39,040 --> 00:08:42,079 Speaker 4: it's quite challenging, I think for us giving guidance based 146 00:08:42,080 --> 00:08:45,800 Speaker 4: on some of these smaller randomized control trials where also 147 00:08:45,880 --> 00:08:49,520 Speaker 4: there's different doses used, and we also know that different 148 00:08:49,559 --> 00:08:53,400 Speaker 4: people respond very differently to different supplements when it comes 149 00:08:53,440 --> 00:08:54,880 Speaker 4: to menopause symptoms. 150 00:08:55,800 --> 00:08:58,880 Speaker 2: Well, it makes me wonder if we're even entering into 151 00:08:59,000 --> 00:09:04,720 Speaker 2: menopause with our nutrition up to par because I just 152 00:09:04,760 --> 00:09:10,720 Speaker 2: started taking zinc selenium vitamin A to kind of help 153 00:09:10,840 --> 00:09:15,559 Speaker 2: balance out my hormones and it has changed my life. 154 00:09:15,840 --> 00:09:18,080 Speaker 2: I have realized in the past couple of weeks I 155 00:09:18,120 --> 00:09:20,240 Speaker 2: have been walking around this earth vitamin efficient for the 156 00:09:20,240 --> 00:09:24,840 Speaker 2: past fifteen years. I don't have pain in my periods anymore, 157 00:09:25,920 --> 00:09:29,640 Speaker 2: my skin looks better, I feel better, And I'm wondering 158 00:09:29,640 --> 00:09:34,080 Speaker 2: if we're even if we're entering into menopause nutrients deficient. 159 00:09:35,000 --> 00:09:38,000 Speaker 4: Yeah, I think, you know, that's an interesting point. I 160 00:09:38,120 --> 00:09:41,559 Speaker 4: hold a view that I think most people consuming a 161 00:09:41,640 --> 00:09:45,319 Speaker 4: reasonable diet have all of the nutrients they need. Many 162 00:09:45,360 --> 00:09:48,160 Speaker 4: of us that actually have the best diets tend to 163 00:09:48,200 --> 00:09:50,920 Speaker 4: be the ones that over worry about it or health 164 00:09:50,960 --> 00:09:53,880 Speaker 4: optimize as a psychll them the people that need to worry, 165 00:09:53,960 --> 00:09:56,960 Speaker 4: the people that really have no interest in their diet 166 00:09:57,320 --> 00:10:00,320 Speaker 4: or or you know, understand the importance of diet. But 167 00:10:00,400 --> 00:10:02,600 Speaker 4: in the UK and the US, there's actually very small 168 00:10:02,640 --> 00:10:06,160 Speaker 4: proportion in my opinion, who are actually deficient in certain nutrients. 169 00:10:06,679 --> 00:10:09,960 Speaker 4: What we do know, though, is that different people absorb 170 00:10:10,400 --> 00:10:16,000 Speaker 4: nutrients differently. Take for example, protein, we know that some 171 00:10:16,080 --> 00:10:19,760 Speaker 4: people absorb all of the protein that they're eating. We 172 00:10:19,800 --> 00:10:22,640 Speaker 4: know that some people absorb very little of it. And 173 00:10:22,679 --> 00:10:24,760 Speaker 4: so I think this is where it's really important to 174 00:10:24,800 --> 00:10:27,880 Speaker 4: see what works for you. So something for you, you 175 00:10:28,040 --> 00:10:32,240 Speaker 4: felt differently after taking those supplements, but you you know, 176 00:10:32,320 --> 00:10:35,120 Speaker 4: your friends or someone else might not feel differently after 177 00:10:35,160 --> 00:10:38,800 Speaker 4: taking them. So I do think sometimes it's about thinking, Okay, 178 00:10:38,840 --> 00:10:40,840 Speaker 4: you know, yeah, I do have a moderately healthy diet, 179 00:10:40,840 --> 00:10:43,800 Speaker 4: but I don't quite feel right. Let me try something 180 00:10:43,840 --> 00:10:47,720 Speaker 4: and see what works. And I think this really really 181 00:10:47,800 --> 00:10:52,920 Speaker 4: applies to menopause supplements that are sold as well. So 182 00:10:53,040 --> 00:10:56,240 Speaker 4: the one supplement that we know there is reasonable evidence 183 00:10:56,320 --> 00:10:59,920 Speaker 4: for are soy eyes of Flay Vonnes And this is 184 00:11:00,040 --> 00:11:03,760 Speaker 4: a great example of how we all respond very differently, 185 00:11:03,800 --> 00:11:05,720 Speaker 4: and we all need to work out what works for 186 00:11:05,840 --> 00:11:09,240 Speaker 4: us as an individual rather than listen to what one 187 00:11:09,320 --> 00:11:13,160 Speaker 4: influencer or another kind of social media person might be 188 00:11:13,240 --> 00:11:14,120 Speaker 4: advocating for. 189 00:11:15,800 --> 00:11:17,600 Speaker 2: We've got to take a quick break ball we write 190 00:11:17,600 --> 00:11:31,280 Speaker 2: back with Professor Sarah Berry, and we're back with Professor 191 00:11:31,360 --> 00:11:32,000 Speaker 2: Sarah Berry. 192 00:11:33,360 --> 00:11:36,720 Speaker 3: Professor Berry, I was interested to see that you've studied 193 00:11:36,760 --> 00:11:37,920 Speaker 3: snacking in the past. 194 00:11:38,080 --> 00:11:39,520 Speaker 1: What's the truth about snacking? 195 00:11:39,559 --> 00:11:41,880 Speaker 3: Because some people say it's okay as long as it's 196 00:11:41,920 --> 00:11:44,840 Speaker 3: high protein, and some people totally write off snacks altogether. 197 00:11:45,480 --> 00:11:46,959 Speaker 1: So hit us with the facts. 198 00:11:47,600 --> 00:11:49,880 Speaker 4: I love that you've asked me about snacking. It's one 199 00:11:49,920 --> 00:11:53,839 Speaker 4: of my favorite topics. So what we know is that 200 00:11:53,920 --> 00:11:56,280 Speaker 4: we get a huge amount of our energy from snacks. 201 00:11:56,480 --> 00:11:58,800 Speaker 4: So in the UK and the US, we get about 202 00:11:58,880 --> 00:12:03,000 Speaker 4: twenty five end of our total daily calories from snacks. 203 00:12:03,679 --> 00:12:06,840 Speaker 4: Now what's great about that is it means it's the 204 00:12:06,880 --> 00:12:11,520 Speaker 4: single simplest dietary strategy that we can implement to improve 205 00:12:11,520 --> 00:12:14,840 Speaker 4: our health. If we're getting a quarter of our calories 206 00:12:14,880 --> 00:12:17,720 Speaker 4: from just snacks, which tend to be under our own 207 00:12:17,760 --> 00:12:20,840 Speaker 4: self control because my dinner is dictated by what my 208 00:12:20,880 --> 00:12:23,880 Speaker 4: fussy kids will eat. My lunch is dictated by where 209 00:12:23,920 --> 00:12:26,679 Speaker 4: I happen to be in the office, out on the streets, etc. 210 00:12:27,280 --> 00:12:31,640 Speaker 4: But snacks, for many of us, we can actually control ourselves. 211 00:12:31,920 --> 00:12:35,720 Speaker 4: We did some research looking at whether snacking itself is 212 00:12:35,760 --> 00:12:38,640 Speaker 4: bad for our health or whether actually it just matters 213 00:12:38,640 --> 00:12:40,880 Speaker 4: what you snack on or how important is the time 214 00:12:40,920 --> 00:12:43,720 Speaker 4: of day that you snack, And what we found was 215 00:12:43,760 --> 00:12:47,720 Speaker 4: that this grazing style pattern of eating or having multiple snacks, 216 00:12:47,880 --> 00:12:50,720 Speaker 4: as long as they were healthy snacks, were not associated 217 00:12:50,760 --> 00:12:54,080 Speaker 4: with any unfavorable health effects. When it became a problem 218 00:12:54,240 --> 00:12:57,640 Speaker 4: was purely if you were eating unhealthy snacks. Another thing 219 00:12:57,679 --> 00:13:00,319 Speaker 4: we looked at was the timing of snacking, and there 220 00:13:00,360 --> 00:13:03,960 Speaker 4: was a large proportion of individuals who were snacking after 221 00:13:04,040 --> 00:13:08,280 Speaker 4: nine in the evening. Those individuals came off worse in 222 00:13:08,360 --> 00:13:11,760 Speaker 4: terms of health outcomes. They had poorer insulin sensitivity, they 223 00:13:11,800 --> 00:13:16,600 Speaker 4: had higher bloodcholesterol, higher blood pressure, greater antiprocity so fab 224 00:13:16,679 --> 00:13:20,320 Speaker 4: tissuer around a belly, which we know is so many 225 00:13:20,400 --> 00:13:23,920 Speaker 4: unfaithful health outcomes, and yet people who were snacking earlier 226 00:13:23,960 --> 00:13:26,440 Speaker 4: in the day, we weren't seeing the same thing. And 227 00:13:26,480 --> 00:13:29,200 Speaker 4: this was even for those people who were snacking on 228 00:13:29,360 --> 00:13:33,920 Speaker 4: healthy snacks after nine o'clock. And I did a study 229 00:13:33,960 --> 00:13:36,800 Speaker 4: about ten years ago where all we want you to 230 00:13:36,840 --> 00:13:39,880 Speaker 4: do is change your snacks to either consume these test 231 00:13:40,080 --> 00:13:42,560 Speaker 4: kind of dummy snacks that are representative of a US 232 00:13:42,640 --> 00:13:46,640 Speaker 4: snack or nuts in this case as Holman nuts. Let's 233 00:13:46,640 --> 00:13:49,400 Speaker 4: see how it impacts your health. And what we found 234 00:13:49,600 --> 00:13:53,319 Speaker 4: was just by changing people snacks improved their blood cholesterol, 235 00:13:53,360 --> 00:13:57,480 Speaker 4: improved their insolent sensitivity, improved their blood vessel functional and 236 00:13:57,559 --> 00:14:00,360 Speaker 4: the improvement that we saw in blood vessel function actually 237 00:14:00,400 --> 00:14:04,600 Speaker 4: equated to a thirty percent reduction in cardiovascular disease risk 238 00:14:05,240 --> 00:14:09,240 Speaker 4: just from changing snacking. And I love to use snacking 239 00:14:09,280 --> 00:14:12,600 Speaker 4: as an example of where yes, for pairing post menopause women, 240 00:14:12,640 --> 00:14:15,920 Speaker 4: we've talked about how diet impacts their symptoms and how 241 00:14:16,000 --> 00:14:19,600 Speaker 4: diet is really important because of their sudden change in risk. 242 00:14:19,760 --> 00:14:23,320 Speaker 4: So actually, you know, thinking about focusing on something simple 243 00:14:23,440 --> 00:14:27,480 Speaker 4: like your snacks could have a really profound impact on 244 00:14:27,520 --> 00:14:29,040 Speaker 4: your own for long term health. 245 00:14:30,360 --> 00:14:32,640 Speaker 2: Is it more important to focus on when we eat 246 00:14:32,960 --> 00:14:34,240 Speaker 2: or what we eat for snacks? 247 00:14:35,520 --> 00:14:38,120 Speaker 4: I would say it's more important to focus on what 248 00:14:38,160 --> 00:14:42,280 Speaker 4: we eat for snacks, but I would say it's also 249 00:14:42,320 --> 00:14:45,560 Speaker 4: important to consider when we eat, but I would say 250 00:14:45,600 --> 00:14:48,600 Speaker 4: not just for snacks, for food overall. We know that, 251 00:14:48,920 --> 00:14:52,680 Speaker 4: you know, it's really important to consider our circasian rhythm. 252 00:14:52,760 --> 00:14:55,000 Speaker 4: We know that in our body, every cell has its 253 00:14:55,040 --> 00:14:58,240 Speaker 4: own little body clock. We know that if you eat 254 00:14:58,280 --> 00:15:00,520 Speaker 4: too late in the evening, whether it's this or your 255 00:15:00,560 --> 00:15:04,160 Speaker 4: main meal, that actually you're not eating in tune with 256 00:15:04,280 --> 00:15:08,000 Speaker 4: your body clock, and that we know that therefore how 257 00:15:08,040 --> 00:15:11,480 Speaker 4: you metabolize the food is slightly differently, and that it 258 00:15:11,600 --> 00:15:16,160 Speaker 4: increases risk of many of these intermediary risk factors like 259 00:15:16,200 --> 00:15:20,280 Speaker 4: your blood cholesterol, like your you know, blood pressure, like 260 00:15:20,320 --> 00:15:23,440 Speaker 4: your inflammation, et cetera. We also know if you eat 261 00:15:23,560 --> 00:15:27,160 Speaker 4: later at night, you actually wake up more hungry the 262 00:15:27,200 --> 00:15:30,800 Speaker 4: next morning, which is kind of counterintuitive. So if you're 263 00:15:30,840 --> 00:15:33,800 Speaker 4: eating your snacks or your main meal later in the evening, 264 00:15:34,160 --> 00:15:36,160 Speaker 4: you're going to feel more hungry when you wake up 265 00:15:36,200 --> 00:15:39,520 Speaker 4: than if you finish your meal slightly earlier in the day. 266 00:15:39,840 --> 00:15:41,840 Speaker 4: And I think this is really important again for pairing 267 00:15:41,880 --> 00:15:46,400 Speaker 4: post menopause or women, because our hunger signals are also 268 00:15:46,560 --> 00:15:49,600 Speaker 4: changed during menopause. You know, we have estrogen receptors in 269 00:15:49,680 --> 00:15:51,720 Speaker 4: or nearly every cell in our body. We have loads 270 00:15:51,720 --> 00:15:54,080 Speaker 4: of estrogen receptors in our brain and in our gut, 271 00:15:54,760 --> 00:15:58,440 Speaker 4: and so how we perceive hunger changes slightly as well. 272 00:15:58,720 --> 00:16:01,560 Speaker 4: And I often hear people saying, you know, I'm eating 273 00:16:01,600 --> 00:16:04,840 Speaker 4: exactly what I before the menopause, but I'm hungry all 274 00:16:04,840 --> 00:16:09,840 Speaker 4: the time. Well, it's because our estrogen also impacts our 275 00:16:09,880 --> 00:16:12,920 Speaker 4: perception of hunger. And so this is why, again it's 276 00:16:12,920 --> 00:16:15,960 Speaker 4: so important to think about the timing that you're eating, 277 00:16:16,320 --> 00:16:20,000 Speaker 4: given that we know your hunger signals also change. 278 00:16:20,280 --> 00:16:24,280 Speaker 3: When you think about sugar in your study, do you 279 00:16:24,720 --> 00:16:28,760 Speaker 3: think about and test for the difference between natural sugars 280 00:16:28,760 --> 00:16:32,920 Speaker 3: from fruits and sugar from dessert type items. 281 00:16:33,240 --> 00:16:36,320 Speaker 4: Yeah, good question. So in the research in our cohort 282 00:16:36,360 --> 00:16:39,120 Speaker 4: of seventy thousand women, where we've looked at the association 283 00:16:39,480 --> 00:16:44,640 Speaker 4: between diet and different symptoms, that's where we're starting to 284 00:16:44,720 --> 00:16:48,600 Speaker 4: tease a part added sugar sugar in fruit. We haven't 285 00:16:48,640 --> 00:16:52,440 Speaker 4: actually specifically looked at x grams of sugar in fruit 286 00:16:52,560 --> 00:16:55,440 Speaker 4: versus x grams of added sugar. What we do see 287 00:16:55,520 --> 00:16:59,080 Speaker 4: those that fruit is associated with a lower prevalence of 288 00:16:59,120 --> 00:17:04,520 Speaker 4: symptoms yeat added sugar or products that we know of 289 00:17:04,600 --> 00:17:07,439 Speaker 4: that kind of very heavily processed high in sugar, like 290 00:17:07,800 --> 00:17:12,600 Speaker 4: cakes and pastries, associated with higher prevalence of symptoms. But 291 00:17:12,720 --> 00:17:15,160 Speaker 4: I think that what we need to remember is that 292 00:17:15,680 --> 00:17:19,160 Speaker 4: as well as thinking of the nutrients I either sugar, 293 00:17:19,680 --> 00:17:22,160 Speaker 4: we have to think about food as well in terms 294 00:17:22,200 --> 00:17:25,040 Speaker 4: of the matrix of the food, so the food structure. 295 00:17:25,080 --> 00:17:28,880 Speaker 4: And this is something I've spent many years researching, looking 296 00:17:28,960 --> 00:17:32,080 Speaker 4: at how changing the structure of the food changes how 297 00:17:32,119 --> 00:17:34,720 Speaker 4: we metabolize it. And this is more and more important 298 00:17:34,760 --> 00:17:37,199 Speaker 4: in the current food landscape we live in where so 299 00:17:37,400 --> 00:17:39,960 Speaker 4: much of our food is processed. So this matrix is 300 00:17:40,040 --> 00:17:43,240 Speaker 4: structure of food is change. And so whether you're having 301 00:17:43,280 --> 00:17:47,440 Speaker 4: food is whole fruit, pure d fruit, fruit smoothies or 302 00:17:47,480 --> 00:17:51,320 Speaker 4: fruit juice has quite a different effect in terms of 303 00:17:51,320 --> 00:17:56,120 Speaker 4: how we metabolize it based on how intact the actual 304 00:17:56,240 --> 00:17:58,320 Speaker 4: structure that original food matrix is. 305 00:17:59,600 --> 00:18:01,480 Speaker 2: You've got to say more about that, because all the 306 00:18:01,520 --> 00:18:03,960 Speaker 2: Ariwon burlies a chill went down their spine when you 307 00:18:04,000 --> 00:18:06,919 Speaker 2: said that we metabolize the fruit and smoothies differently. So 308 00:18:07,760 --> 00:18:08,800 Speaker 2: what do you mean by that? 309 00:18:10,240 --> 00:18:13,680 Speaker 4: So I think we need to think as three main areas. 310 00:18:13,840 --> 00:18:18,360 Speaker 4: So nutrients, I fraid you know, macronutriants, PROTD fat, fiber, carbohydrate. 311 00:18:18,840 --> 00:18:22,280 Speaker 4: So if we take almonds as an example of this, 312 00:18:23,000 --> 00:18:25,520 Speaker 4: if you look at the back of pack labeling for almonds, 313 00:18:26,000 --> 00:18:28,720 Speaker 4: that it says that there's one hundred and seventy calories 314 00:18:29,119 --> 00:18:34,199 Speaker 4: per serving of almonds, but actually the matrix are the 315 00:18:34,240 --> 00:18:37,360 Speaker 4: structure of almonds means that we don't absorb all of that. 316 00:18:37,400 --> 00:18:40,000 Speaker 4: We actually only absorb about one hundred and twenty five 317 00:18:40,160 --> 00:18:43,760 Speaker 4: rather than one hundred and seventy calories. And that's because 318 00:18:44,600 --> 00:18:47,879 Speaker 4: nuts contain thousands and thousands and thousands of cells with 319 00:18:48,080 --> 00:18:50,680 Speaker 4: really rigid cell walls, and it's the fat and the 320 00:18:51,080 --> 00:18:54,639 Speaker 4: calories are contained within these really rigid cell walls. We 321 00:18:54,800 --> 00:18:58,560 Speaker 4: swallow us when there are quite big chunks, so they're 322 00:18:58,560 --> 00:19:02,200 Speaker 4: normally about one to two millimeters, but the cell particles, 323 00:19:02,240 --> 00:19:05,560 Speaker 4: the cells inns, are tiny. They're less than a grain 324 00:19:05,600 --> 00:19:09,440 Speaker 4: of sand. So actually a lot of that remains intact 325 00:19:09,520 --> 00:19:12,440 Speaker 4: and it just comes out in your poo. The same 326 00:19:12,480 --> 00:19:17,240 Speaker 4: thing happens in fruit, for example. But what happens is 327 00:19:17,240 --> 00:19:20,560 Speaker 4: is you absorb all of the nutrients, but you change 328 00:19:20,600 --> 00:19:24,240 Speaker 4: the speed at which you absorb these. So if you 329 00:19:24,320 --> 00:19:28,280 Speaker 4: take a whole apple, for example, and then if you 330 00:19:28,440 --> 00:19:32,560 Speaker 4: take apple pure, what you're doing is you're changing the 331 00:19:32,600 --> 00:19:36,560 Speaker 4: texture of the feud, so you're changing how fast you 332 00:19:36,680 --> 00:19:39,720 Speaker 4: eat it. And so what we know is that it 333 00:19:39,760 --> 00:19:42,880 Speaker 4: would take you on average about six minutes to eat 334 00:19:42,880 --> 00:19:46,000 Speaker 4: an apple, It will take you about forty seconds to 335 00:19:46,080 --> 00:19:48,840 Speaker 4: eat the equivalent of pure es, centering your stomach more 336 00:19:48,880 --> 00:19:52,119 Speaker 4: quickly so that you're then releasing it into bloodstream more quickly, 337 00:19:52,160 --> 00:19:54,960 Speaker 4: so you're then getting this big glucose peak. This can 338 00:19:55,040 --> 00:19:57,760 Speaker 4: cause a glucose dip, So two to four hours after 339 00:19:57,800 --> 00:20:00,800 Speaker 4: the meal, you have a dipping glucose. If you have 340 00:20:00,840 --> 00:20:03,199 Speaker 4: a glucose dip after a meal, we know from our 341 00:20:03,240 --> 00:20:05,760 Speaker 4: own research most people go on to eat their next 342 00:20:05,800 --> 00:20:07,879 Speaker 4: meal thirty minutes earlier. They go on to eat one 343 00:20:07,920 --> 00:20:11,000 Speaker 4: hundred calories more at their next meal, three hundred calories 344 00:20:11,040 --> 00:20:14,400 Speaker 4: more over the whole day. And so there's some fantastic 345 00:20:14,440 --> 00:20:17,160 Speaker 4: research that was published many years ago by this guy 346 00:20:17,280 --> 00:20:19,679 Speaker 4: called Haber. This was in the Lancet, This was in 347 00:20:19,760 --> 00:20:23,560 Speaker 4: nineteen seventy seven where he fed people whole apples, pureed 348 00:20:23,560 --> 00:20:26,640 Speaker 4: apples or apple juice, and he saw this big difference 349 00:20:26,640 --> 00:20:29,520 Speaker 4: in the speed in which people were eating their apples. 350 00:20:29,520 --> 00:20:31,760 Speaker 4: And he saw this big difference as well in people's 351 00:20:31,800 --> 00:20:35,679 Speaker 4: self reported hunger and fullness level. So the whole apple 352 00:20:35,800 --> 00:20:38,960 Speaker 4: kept people full of for longer. The apple purea, the 353 00:20:39,000 --> 00:20:42,880 Speaker 4: apple juice didn't keep people us full. They went on 354 00:20:42,960 --> 00:20:45,520 Speaker 4: to consume more. And we see this play out in 355 00:20:45,560 --> 00:20:48,679 Speaker 4: our own studies as well. And what blows my mind 356 00:20:48,560 --> 00:20:51,879 Speaker 4: that these are foods that have exactly the same backupack labeling, 357 00:20:51,920 --> 00:20:55,159 Speaker 4: but how you process them is very different just because 358 00:20:55,160 --> 00:20:58,119 Speaker 4: of the structure. And this is why one of the 359 00:20:58,160 --> 00:21:01,960 Speaker 4: reasons that heavily process foods are not so healthy for us. 360 00:21:02,240 --> 00:21:05,520 Speaker 4: It's not all about the additives or all about emulsifiers 361 00:21:05,600 --> 00:21:07,800 Speaker 4: or what people you know, talk about a lot. It's 362 00:21:07,840 --> 00:21:10,800 Speaker 4: also because you're changing the texture and you're changing the structure, 363 00:21:10,800 --> 00:21:13,800 Speaker 4: and you're changing the availability of the nutrients as well. 364 00:21:14,760 --> 00:21:20,120 Speaker 2: Wow, so it sounds like slower is better like slower absolutely? Yeah? 365 00:21:20,160 --> 00:21:20,760 Speaker 4: Absolutely? 366 00:21:21,240 --> 00:21:25,480 Speaker 2: Wow. Are there any startups that you recommend or services 367 00:21:25,520 --> 00:21:29,520 Speaker 2: that we can try in order to really take a 368 00:21:29,600 --> 00:21:32,959 Speaker 2: comprehensive assessment of our nutrition and just make sure that 369 00:21:33,000 --> 00:21:36,920 Speaker 2: we are completely up to date and nourished. Yeah. 370 00:21:36,920 --> 00:21:41,000 Speaker 4: So, first thing I'd recommend is to try our Zoe menoscale. 371 00:21:41,240 --> 00:21:44,879 Speaker 4: This is a menoscale calculator. It's free for anyone. You 372 00:21:44,920 --> 00:21:47,639 Speaker 4: can go to the Zoe dot com website and then 373 00:21:47,640 --> 00:21:51,199 Speaker 4: it's forward slash menoscale and this is a calculator that 374 00:21:51,280 --> 00:21:55,080 Speaker 4: allows you to measure the burden of menopause symptoms that 375 00:21:55,160 --> 00:21:57,720 Speaker 4: it has on you. And this is really important because 376 00:21:57,760 --> 00:22:01,240 Speaker 4: we're talking about how diet or life might help reduce 377 00:22:01,280 --> 00:22:04,360 Speaker 4: your symptoms. But it's very difficult to measure your symptoms 378 00:22:04,400 --> 00:22:08,720 Speaker 4: because it's so subjective and you know, it's difficult to think, ohll, 379 00:22:08,760 --> 00:22:11,360 Speaker 4: how did I feel yesterday? So it's the first thing 380 00:22:11,359 --> 00:22:14,119 Speaker 4: you can do. You start tracking our symptoms. We often, 381 00:22:14,280 --> 00:22:16,439 Speaker 4: you know, talk in science, right if you can't measure it, 382 00:22:16,520 --> 00:22:18,600 Speaker 4: how can you change it? So it's the first thing, 383 00:22:18,680 --> 00:22:21,320 Speaker 4: start measuring them if you do want to change, whether 384 00:22:21,359 --> 00:22:25,040 Speaker 4: it's through drugs like hormone replacement therapy, or whether it's 385 00:22:25,040 --> 00:22:27,720 Speaker 4: through dieting lifestyle. The other thing you can go to 386 00:22:28,119 --> 00:22:31,320 Speaker 4: is our Zoe website. So Zoe is this science and 387 00:22:31,400 --> 00:22:35,000 Speaker 4: nutrition company that I'm the chief scientist of and there 388 00:22:35,119 --> 00:22:37,920 Speaker 4: is so much actionable advice on our website. We also 389 00:22:37,960 --> 00:22:40,639 Speaker 4: have a podcast called the Zoe Science and Nutrition Podcast. 390 00:22:41,320 --> 00:22:46,840 Speaker 4: We do a lot of episodes around women's health, menopause. 391 00:22:47,600 --> 00:22:50,400 Speaker 4: But it's all about how we can use diarting lifestyle 392 00:22:50,520 --> 00:22:54,399 Speaker 4: to improve our health, whether you're menopausal or not. And 393 00:22:54,440 --> 00:22:56,679 Speaker 4: so you can just go to the ZOO website and 394 00:22:56,720 --> 00:22:59,760 Speaker 4: find out all about those different opportunities. 395 00:23:01,400 --> 00:23:05,240 Speaker 2: Thank you so much for that. Those are great resources, Pleasure. 396 00:23:05,880 --> 00:23:08,680 Speaker 3: Professor Barry, it was wonderful to speak with you. Thank 397 00:23:08,720 --> 00:23:10,160 Speaker 3: you for joining us today. 398 00:23:10,840 --> 00:23:12,320 Speaker 4: Pleasure, thank you for having me on. 399 00:23:14,560 --> 00:23:17,359 Speaker 3: Sarah Barry is the chief scientist at ZOE and a 400 00:23:17,400 --> 00:23:21,240 Speaker 3: professor at King's College in London. We have to take 401 00:23:21,240 --> 00:23:24,080 Speaker 3: another short break, but we'll be back in just a minute. 402 00:23:24,280 --> 00:23:32,760 Speaker 1: Don't go anywhere, and we're. 403 00:23:32,640 --> 00:23:36,359 Speaker 2: Back, Danielle. As you know, we've teamed up with our 404 00:23:36,400 --> 00:23:39,600 Speaker 2: friends at Exact Sciences, makers of the Coliguard test, to 405 00:23:39,640 --> 00:23:42,960 Speaker 2: clear up some misconceptions about screening for colon cancer. So 406 00:23:43,000 --> 00:23:44,800 Speaker 2: today I thought we could put some of our knowledge 407 00:23:44,840 --> 00:23:45,359 Speaker 2: to the test. 408 00:23:45,560 --> 00:23:47,840 Speaker 3: There's nothing I like more than making sure our bright 409 00:23:47,880 --> 00:23:51,119 Speaker 3: side besties are informed to make the best decisions for 410 00:23:51,160 --> 00:23:51,679 Speaker 3: their health. 411 00:23:52,000 --> 00:23:53,840 Speaker 2: Okay, I'm going to give you some scenarios and you 412 00:23:53,920 --> 00:23:55,919 Speaker 2: let me know if it's a fact or a misconception. 413 00:23:56,240 --> 00:23:59,879 Speaker 2: You ready, Let's do it first, up, Many patients with 414 00:24:00,040 --> 00:24:03,560 Speaker 2: early stage colon cancer have no symptoms and are diagnosed 415 00:24:03,600 --> 00:24:04,200 Speaker 2: through screening. 416 00:24:04,720 --> 00:24:05,399 Speaker 1: That's a fact. 417 00:24:06,280 --> 00:24:09,240 Speaker 2: You're right. Many people think that colon cancer always has 418 00:24:09,280 --> 00:24:12,200 Speaker 2: definitive symptoms, but that's a complete misconception. 419 00:24:12,600 --> 00:24:12,919 Speaker 1: Okay. 420 00:24:13,080 --> 00:24:15,560 Speaker 2: Next up, If you eat a healthy diet and exercise, 421 00:24:15,880 --> 00:24:17,959 Speaker 2: you are at a low risk for colon cancer. 422 00:24:18,560 --> 00:24:19,640 Speaker 1: That's a misconception. 423 00:24:20,440 --> 00:24:22,919 Speaker 2: You're right. No one is at a low risk for 424 00:24:22,960 --> 00:24:26,479 Speaker 2: colon cancer. Even with no family history, you're still at 425 00:24:26,520 --> 00:24:29,520 Speaker 2: an average risk. I was surprised to learn that seventy 426 00:24:29,560 --> 00:24:32,600 Speaker 2: percent of people with colon cancer have no family history. 427 00:24:33,119 --> 00:24:36,280 Speaker 3: That's what makes testing so important. Okay, I have one 428 00:24:36,320 --> 00:24:39,200 Speaker 3: for you, Simone. You should start screening for colon cancer 429 00:24:39,280 --> 00:24:40,360 Speaker 3: at the age of fifty. 430 00:24:41,119 --> 00:24:44,080 Speaker 2: You know, I have heard that before, but based on 431 00:24:44,119 --> 00:24:47,119 Speaker 2: our earlier facts, I actually think it should be younger 432 00:24:47,160 --> 00:24:47,399 Speaker 2: than that. 433 00:24:47,960 --> 00:24:51,080 Speaker 3: Exactly, if you're at average risk. The recommended age to 434 00:24:51,119 --> 00:24:54,199 Speaker 3: start screening is forty five, and if you're eligible, the 435 00:24:54,240 --> 00:24:56,160 Speaker 3: colon Guard test is easy to use. 436 00:24:57,400 --> 00:25:00,000 Speaker 2: I know that is a fact. The Colargard test is 437 00:25:00,080 --> 00:25:02,719 Speaker 2: an easy to use way to screen for colon cancer. 438 00:25:02,920 --> 00:25:05,240 Speaker 2: It's non invasive, you don't have to take off time 439 00:25:05,280 --> 00:25:08,520 Speaker 2: from work and there's no special prep needed. It's delivered 440 00:25:08,520 --> 00:25:10,920 Speaker 2: to your door and after a sample is collected at home, 441 00:25:11,400 --> 00:25:13,520 Speaker 2: you ship it back to the laboratory for testing and 442 00:25:13,600 --> 00:25:15,679 Speaker 2: results are available within about two weeks. 443 00:25:16,200 --> 00:25:19,159 Speaker 3: And the Coligard test can detect pre cancerous polyups and 444 00:25:19,240 --> 00:25:22,719 Speaker 3: helps address any issues now before it becomes serious if 445 00:25:22,800 --> 00:25:23,600 Speaker 3: left untreated. 446 00:25:24,520 --> 00:25:26,119 Speaker 2: How do you know so much about all this? 447 00:25:26,880 --> 00:25:29,320 Speaker 3: I have friends that have been diagnosed with colon cancer 448 00:25:29,400 --> 00:25:32,400 Speaker 3: and luckily they caught it early, so I know how 449 00:25:32,440 --> 00:25:35,080 Speaker 3: important this is. So if you're forty five or older 450 00:25:35,119 --> 00:25:38,200 Speaker 3: and at average risk, ask your healthcare provider about screening 451 00:25:38,240 --> 00:25:41,280 Speaker 3: for colon cancer with the Coliguard test. You can also 452 00:25:41,320 --> 00:25:44,800 Speaker 3: request a Coliguard prescription today through a telehealth provider at 453 00:25:44,840 --> 00:25:46,760 Speaker 3: coliguard dot com slash podcast. 454 00:25:47,320 --> 00:25:50,120 Speaker 2: The Coligard test is intended to screen adults forty five 455 00:25:50,160 --> 00:25:53,159 Speaker 2: and older at average risk for colorectal cancer. Do not 456 00:25:53,280 --> 00:25:56,440 Speaker 2: use a Coligard test if you've had adenomas, have inflammatory 457 00:25:56,480 --> 00:26:00,159 Speaker 2: bowel disease and certain hereditary syndromes, or a personal or 458 00:26:00,160 --> 00:26:03,639 Speaker 2: family history of colorectal cancer. The Colliguard test is not 459 00:26:03,680 --> 00:26:07,160 Speaker 2: a replacement for colonoscopy and high risk patients. Colliguard test 460 00:26:07,160 --> 00:26:09,720 Speaker 2: performance in adults ages forty five to forty nine is 461 00:26:09,840 --> 00:26:12,439 Speaker 2: estimated based on a large clinical study of patients fifty 462 00:26:12,440 --> 00:26:16,040 Speaker 2: and older. False positives and false negatives can occur. Coliguard 463 00:26:16,119 --> 00:26:23,440 Speaker 2: is available by prescription only. That's it for today's show. Tomorrow, 464 00:26:23,520 --> 00:26:26,160 Speaker 2: it's Thanksgiving, y'all, and we are ringing in the holiday 465 00:26:26,200 --> 00:26:29,560 Speaker 2: with an encore presentation of one of our favorite episodes, 466 00:26:29,600 --> 00:26:32,399 Speaker 2: all about the art of gathering with expert gatherer and 467 00:26:32,520 --> 00:26:38,320 Speaker 2: author Priya Parker. You don't want to miss it. Join 468 00:26:38,359 --> 00:26:41,720 Speaker 2: the conversation using hashtag the bright Side and connect with 469 00:26:41,800 --> 00:26:45,000 Speaker 2: us on social media at Hello Sunshine on Instagram and 470 00:26:45,320 --> 00:26:48,359 Speaker 2: at the bright Side Pod on TikTok oh, and feel 471 00:26:48,400 --> 00:26:51,840 Speaker 2: free to tag us at Simone Voice and at Danielle Robe. 472 00:26:52,359 --> 00:26:55,320 Speaker 3: Listen and follow The bright Side on the iHeartRadio app, 473 00:26:55,359 --> 00:26:58,040 Speaker 3: Apple Podcasts, or wherever you get your podcasts. 474 00:26:58,440 --> 00:27:02,800 Speaker 2: See you tomorrow, folks, Keep looking on the bright side.