1 00:00:02,040 --> 00:00:07,040 Speaker 1: Welcome to brain Stuff from How Stuff Works, Hey, brain Stuff, 2 00:00:07,080 --> 00:00:10,160 Speaker 1: Lauren Vogel bomb here. If you've been diagnosed with diabetes, 3 00:00:10,480 --> 00:00:12,680 Speaker 1: no doubt you've been told to change your eating habits 4 00:00:12,920 --> 00:00:16,759 Speaker 1: more veggies, fewer sweets, and to get more exercise. These 5 00:00:16,800 --> 00:00:19,520 Speaker 1: actions were thought to control your diabetes, but not to 6 00:00:19,560 --> 00:00:22,079 Speaker 1: reverse it, but a paper published in the b m 7 00:00:22,160 --> 00:00:25,400 Speaker 1: J says the type two diabetes is indeed reversible for 8 00:00:25,520 --> 00:00:29,240 Speaker 1: many patients who lose around fifteen kilograms or thirty three pounds. 9 00:00:30,080 --> 00:00:33,360 Speaker 1: Diabetes is a chronic condition that has been rising rapidly 10 00:00:33,400 --> 00:00:36,320 Speaker 1: throughout the world. It affected eight point five percent of 11 00:00:36,360 --> 00:00:40,440 Speaker 1: the world's population, about four hundred and twenty two million people, 12 00:00:40,800 --> 00:00:44,760 Speaker 1: up from four point seven percent in the most common 13 00:00:44,800 --> 00:00:48,000 Speaker 1: form of diabetes is type two diabetes, also known as 14 00:00:48,080 --> 00:00:51,880 Speaker 1: adult onset diabetes. It occurs when the body doesn't effectively 15 00:00:51,960 --> 00:00:54,920 Speaker 1: use the insulin it produces. Insulin being the hormone that 16 00:00:54,920 --> 00:00:57,920 Speaker 1: regulates blood sugar. If your blood sugar level is too 17 00:00:58,000 --> 00:01:00,600 Speaker 1: high and is not treated, it can lead to severe 18 00:01:00,640 --> 00:01:05,280 Speaker 1: problems like blindness, stroke, kidney failure, and foot amputations. Type 19 00:01:05,280 --> 00:01:08,880 Speaker 1: two diabetes is almost always directly tied to physical inactivity 20 00:01:08,920 --> 00:01:12,240 Speaker 1: and extra body weight. We spoke with paper co author 21 00:01:12,360 --> 00:01:16,399 Speaker 1: ROYD Taylor, Professor of Medicine and Metabolism at Newcastle University, 22 00:01:16,560 --> 00:01:20,000 Speaker 1: via email. The belief amongst doctors and scientists is that 23 00:01:20,080 --> 00:01:24,240 Speaker 1: type two diabetes is irreversible, always get steadily worse, demanding 24 00:01:24,280 --> 00:01:28,000 Speaker 1: more and more drugs than insulin. Patient groups advised that 25 00:01:28,040 --> 00:01:30,399 Speaker 1: the first step for someone newly diagnosed is to get 26 00:01:30,480 --> 00:01:33,200 Speaker 1: used to the idea of dealing with a lifelong illness. 27 00:01:34,040 --> 00:01:36,399 Speaker 1: His research is the latest chapter in year's worth of 28 00:01:36,440 --> 00:01:39,760 Speaker 1: investigation about type two diabetes. In two thousand and six, 29 00:01:39,880 --> 00:01:42,720 Speaker 1: he noticed that liver function tests done in patients were 30 00:01:42,840 --> 00:01:46,000 Speaker 1: usually abnormal or on the high side. Then he saw 31 00:01:46,080 --> 00:01:49,680 Speaker 1: research that patients who had undergone bariatric surgery enjoyed normal 32 00:01:49,760 --> 00:01:53,920 Speaker 1: fasting glucose levels within one week of the operation. He said, 33 00:01:54,120 --> 00:01:56,600 Speaker 1: although it became widely believed that this was an effect 34 00:01:56,680 --> 00:01:59,400 Speaker 1: of special hormones produced by the gut, it was clear 35 00:01:59,400 --> 00:02:01,760 Speaker 1: to me that it simply be the sharp decrease in 36 00:02:01,840 --> 00:02:05,920 Speaker 1: food intake. I published a hypothesis, the twin cycle hypothesis, 37 00:02:06,120 --> 00:02:09,280 Speaker 1: suggesting how everything might be explained by too much fat 38 00:02:09,320 --> 00:02:12,680 Speaker 1: in the liver and pancreas. Then set about testing that hypothesis. 39 00:02:14,000 --> 00:02:16,959 Speaker 1: His hunch was proved inn and after that the group 40 00:02:17,040 --> 00:02:19,760 Speaker 1: conducted a larger study to find out if those benefits 41 00:02:19,760 --> 00:02:23,200 Speaker 1: continued long term. The scientists were pleased to discover that 42 00:02:23,240 --> 00:02:26,320 Speaker 1: remission does stay constant after a return to normal eating, 43 00:02:26,560 --> 00:02:30,760 Speaker 1: provided that these subjects maintain a steady weight. Unfortunately, a 44 00:02:30,760 --> 00:02:33,280 Speaker 1: lot of patients and doctors haven't cluded into this finding 45 00:02:33,280 --> 00:02:36,600 Speaker 1: that diabetes can go into remission. The b MJ paper 46 00:02:36,680 --> 00:02:39,480 Speaker 1: was actually written to draw more attention to the reversibility 47 00:02:39,520 --> 00:02:43,480 Speaker 1: of the condition and to incentivize everyone to strive for remission. 48 00:02:44,280 --> 00:02:47,320 Speaker 1: Taylor said remission is a great advantage to people with 49 00:02:47,360 --> 00:02:50,959 Speaker 1: type two diabetes. Although many are content to continue taking 50 00:02:50,960 --> 00:02:54,440 Speaker 1: the tablets or insulin and risk loss of eyesight, feet, etcetera, 51 00:02:54,720 --> 00:02:58,239 Speaker 1: there are large numbers desperate to escape from type two diabetes. 52 00:02:59,000 --> 00:03:01,639 Speaker 1: The author's call for to record patients who have gone 53 00:03:01,639 --> 00:03:05,120 Speaker 1: into remission, Taylor said, in the UK National Health Service 54 00:03:05,200 --> 00:03:08,840 Speaker 1: there is a special coding category to describe diabetes in remission. 55 00:03:09,200 --> 00:03:12,120 Speaker 1: It allows physicians to still be paid, ex sufferers to 56 00:03:12,240 --> 00:03:15,000 Speaker 1: not have to call themselves diabetic, and annual checks to 57 00:03:15,040 --> 00:03:18,679 Speaker 1: be done to help motivation to keep weight steady to 58 00:03:18,720 --> 00:03:22,200 Speaker 1: achieve remission diabetes type two patients must get their hemoglobin 59 00:03:22,280 --> 00:03:25,000 Speaker 1: A one c blood level to normal levels for one 60 00:03:25,080 --> 00:03:29,840 Speaker 1: year without assistance from diabetes medication. On its website, the 61 00:03:29,880 --> 00:03:33,120 Speaker 1: American Diabetes Association notes that it's very rare for patients 62 00:03:33,160 --> 00:03:37,360 Speaker 1: diabetes to go into remission unless they've had bariatric surgery. However, 63 00:03:37,480 --> 00:03:41,280 Speaker 1: the European diabetes forum diabetes dot co dot uk is 64 00:03:41,280 --> 00:03:44,000 Speaker 1: more up beat, stating that low carb diets like the 65 00:03:44,040 --> 00:03:47,560 Speaker 1: Mediterranean diet and commitment to exercise, as well as bariatric 66 00:03:47,600 --> 00:03:51,320 Speaker 1: surgery have all helped some people with diabetes to achieve remission. 67 00:03:52,200 --> 00:03:54,160 Speaker 1: If you or someone you know is living with type 68 00:03:54,160 --> 00:03:57,040 Speaker 1: two diabetes, consider talking to a doctor about steps to 69 00:03:57,080 --> 00:04:05,080 Speaker 1: take toward remission. Today's episode was written by Alia Hoyt 70 00:04:05,160 --> 00:04:07,480 Speaker 1: and produced by Tyler Clang. For more on this and 71 00:04:07,640 --> 00:04:10,360 Speaker 1: lots of other healthy topics, visit our home planet, how 72 00:04:10,400 --> 00:04:22,800 Speaker 1: Stuff Works dot com