WEBVTT - How Migraines Work 0:00:00.280 --> 0:00:02.840 Brought to you by the reinvented two thousand twelve camera. 0:00:03.160 --> 0:00:07.560 It's ready. Are you welcome to stuff you should know 0:00:08.160 --> 0:00:16.360 from house toff works dot com? Hey, and welcome to 0:00:16.400 --> 0:00:19.079 the podcast on Josh Clark with Me. Is always this 0:00:19.200 --> 0:00:23.240 Charles Chuck Bryant suffering from what looks like a headache. 0:00:24.079 --> 0:00:27.960 And I just did that. Okay, that was method podcasting 0:00:28.840 --> 0:00:32.400 and I was falling for it on a purpose. So 0:00:32.840 --> 0:00:35.800 what's your witty intro? Because this is a fan request? 0:00:37.040 --> 0:00:41.080 Is this super fan buddies? Yeah? Cooper Chuck? Oh was it? Yeah? 0:00:41.159 --> 0:00:44.559 Does he have migraines? Cooper? Uh? Well, we'll say his name, 0:00:44.560 --> 0:00:46.720 Aaron Cooper. He didn't mind. He's all over the place. 0:00:46.760 --> 0:00:49.559 He uh has been asking for this podcast for a 0:00:49.560 --> 0:00:52.800 couple of years and I finally wrote him to day. 0:00:52.800 --> 0:00:56.000 I was like, Merry Christmas, jerk. Yeah, can you imagine 0:00:56.080 --> 0:00:59.880 having a migraine that's bad enough? Having a migraine in 0:01:00.080 --> 0:01:04.200 Kansas is like a million times words and having to 0:01:04.240 --> 0:01:07.920 listen to us make fun of it. Uh, Aaron requested this, 0:01:08.000 --> 0:01:09.640 and we I just want to go ahead and say 0:01:09.640 --> 0:01:13.600 Aaron has the RS, which we'll get to. He has 0:01:13.640 --> 0:01:17.880 alternating sides that they occur on sounds pretty been having 0:01:18.000 --> 0:01:21.199 since he was a kid, and he has his triggers 0:01:22.240 --> 0:01:26.920 food based sometimes sugar, caffeine, water, and now, and he 0:01:26.959 --> 0:01:29.920 has his treatment now, which is when he sees the aura, 0:01:30.840 --> 0:01:35.880 he knows it's coming too ecceteran migraines, dark room and 0:01:36.319 --> 0:01:38.320 water and nap for like an hour and a half. 0:01:38.319 --> 0:01:40.560 And he says he's gotten way better at staving them off. 0:01:41.760 --> 0:01:45.360 So that's Kopa said it would feature you, so they're 0:01:45.360 --> 0:01:49.160 not give me my money. There's the introduction. Is it really? Oh, 0:01:49.200 --> 0:01:52.560 I'm glad you did that because I had none? Okay, great, Yeah, 0:01:53.240 --> 0:01:59.240 welcome to the podcast. So Chuck, yes, uh, well, let's 0:01:59.280 --> 0:02:01.440 talk about my brains. It sounds like, from what you 0:02:01.560 --> 0:02:07.000 just described, Cooper is sadly um a pretty typical migraine 0:02:07.000 --> 0:02:09.600 stuffer in that you have to really pay attention to 0:02:09.639 --> 0:02:12.799 it yourself, figure out what works for you, what triggers it, 0:02:12.919 --> 0:02:18.120 and when it's coming, and basically treat yourself because doctors 0:02:18.200 --> 0:02:22.600 don't really have much of an idea of what migraines are. Um, 0:02:22.880 --> 0:02:25.880 we know that they're not headaches because headaches are caused 0:02:25.880 --> 0:02:30.000 by vaso constriction in the brain tightening of blood vessels, right, 0:02:30.040 --> 0:02:33.200 that is right. Just Uh, they used to think that 0:02:33.280 --> 0:02:37.720 migraines were caused by vaso dilation, just the opening of 0:02:37.720 --> 0:02:42.160 blood vessels in the brain. That's still a common factor 0:02:42.440 --> 0:02:47.639 in migraines. But that's not the only peace to the puzzle, right, Um, 0:02:47.760 --> 0:02:51.600 Like you said, my migraines typically focus on one side 0:02:51.680 --> 0:02:55.120 or the other. Um, they seem to be passed down 0:02:55.160 --> 0:02:59.000 among families. Yeah, you're I think if one of your 0:02:59.000 --> 0:03:02.280 parents had had my brains, you're about fifty more likely, 0:03:02.320 --> 0:03:04.600 and if both of your parents had them, you're seventy 0:03:04.600 --> 0:03:08.800 percent more likely. Now you were sevent in trouble. Yeah, yeah, 0:03:09.520 --> 0:03:13.799 your parents. Have you ever had one? No, you don't 0:03:13.840 --> 0:03:15.799 get them. No, And I seem to remember my mom 0:03:15.960 --> 0:03:20.200 or my dad saying that they had them. But it 0:03:20.280 --> 0:03:22.839 may have been a cluster headache. We'll get to those later. 0:03:22.840 --> 0:03:25.240 There's there was ten times likelier that it was your 0:03:25.280 --> 0:03:28.679 dad that said that. Then, because menton has more likely 0:03:28.680 --> 0:03:31.040 to get cluster heady. But women are more likely to 0:03:31.040 --> 0:03:34.480 get migraines, right, Like, Uh, eight percent of women get 0:03:34.560 --> 0:03:36.920 migraines and six percent of men. That would make women 0:03:37.000 --> 0:03:40.360 three times more likely. Yeah, that's in America, at least 0:03:40.400 --> 0:03:45.520 twelve to twenty four Americans have migraines million. Right, there's 0:03:45.520 --> 0:03:49.840 a hundred homeless people worldwide, so they can and this 0:03:50.000 --> 0:03:52.640 this is the general overview. They can last anywhere from 0:03:52.640 --> 0:03:58.040 a few minutes to the some reports of years without stop, 0:03:58.120 --> 0:04:02.360 which can you imagine, now, why would you be alive still? Yeah, exactly, 0:04:02.440 --> 0:04:07.040 Like I can't imagine that even an hour, it would 0:04:07.040 --> 0:04:11.280 be horrible, but years, days, months, it's horrible. I don't 0:04:11.320 --> 0:04:13.280 get headaches much at all, but when I do, I'm 0:04:13.280 --> 0:04:17.000 not a happy camper. Loss of vision, vomiting tremors, stroke 0:04:17.080 --> 0:04:20.400 like symptoms. These are what migraines can do to you, right, 0:04:20.480 --> 0:04:23.240 and um that you hit upon something with that last one, 0:04:23.279 --> 0:04:28.440 the stroke conditions or stroke symptoms. UM. The the migraine 0:04:28.440 --> 0:04:30.479 has been kind of it's been taken out of the 0:04:30.480 --> 0:04:33.640 realm of headaches and has recently been reclassified as a 0:04:33.720 --> 0:04:38.400 neurobiological condition. And UM the stroke symptoms you talked about 0:04:38.480 --> 0:04:44.200 some some migraines, some type of migraine. UM see sufferers 0:04:44.360 --> 0:04:48.840 suffer from UM these stroke like symptoms, like they have 0:04:48.920 --> 0:04:51.840 cognitive impairment, like they can't recognize words all of a 0:04:51.880 --> 0:04:55.000 sudden like their armigo numb yeah. Um, they can't talk 0:04:55.200 --> 0:05:00.720 correctly and when that happens, there's a migraine that coming. Right. Yeah, 0:05:01.160 --> 0:05:05.680 there's are set up. Oh. Also triggers. That's a big 0:05:05.680 --> 0:05:09.200 one too. Yeah, that's there's there's always a trigger and 0:05:09.279 --> 0:05:11.400 they can we'll talk about the triggers in detail, but 0:05:11.440 --> 0:05:14.000 they can vary. It's all according to the person. They're 0:05:14.000 --> 0:05:17.400 different for everybody. Right, So here's what we know so 0:05:17.440 --> 0:05:21.080 far as going on in the brain. Right, Um, there's 0:05:21.120 --> 0:05:23.880 some sort of trigger, right, and we'll talk about triggers. 0:05:23.920 --> 0:05:27.800 But let's say you, um the example used as you 0:05:28.160 --> 0:05:31.080 didn't eat like you normally do. Yeah, you didn't get 0:05:31.080 --> 0:05:35.560 out for lunch at noon, um, and something in that 0:05:36.320 --> 0:05:39.400 lack of routine or changing routine sets off the NO 0:05:39.560 --> 0:05:46.000 susceptors in the brain pain receptors the remember yeah, um. 0:05:46.160 --> 0:05:51.440 The NO susceptors release chemicals called neuropeptides, and neuropeptides are 0:05:51.880 --> 0:05:56.080 unique their neurotransmitters, which means that this is how one 0:05:56.120 --> 0:06:00.320 neuron communicates with another. They create the electrochemical imp that 0:06:00.360 --> 0:06:02.160 creates the language of the brain. Right, you know a 0:06:02.160 --> 0:06:04.400 lot about the stuff now I do well. Version in 0:06:04.400 --> 0:06:07.200 the brain, my friend. Yeah. But the and this is 0:06:07.240 --> 0:06:12.640 where it relates to migraines. Neuropeptides, these proteins UM can 0:06:12.680 --> 0:06:16.320 be a neurotransmitter or they could be a neuromodulator, and 0:06:16.360 --> 0:06:19.520 a neuromodulator can turn the volume up or down on 0:06:19.560 --> 0:06:23.920 the transmission of other neurotransmitters. Right. In this case, these 0:06:23.960 --> 0:06:28.240 neuropeptides turn the volume way up on the pain receptors 0:06:28.240 --> 0:06:31.000 in the brain, and so all of a sudden you 0:06:31.040 --> 0:06:33.640 start to experience a headache like you've never had before 0:06:33.640 --> 0:06:37.800 in your entire life. Yeah. Basically makes these pain sensing 0:06:37.839 --> 0:06:41.560 cells way more sensitive than they ever would have been, right. Um. 0:06:41.839 --> 0:06:46.040 The the neuropeptides also, for some reason relax blood vessels 0:06:46.040 --> 0:06:49.240 in the brain, which causes the vasidilation. Um. But they 0:06:49.279 --> 0:06:53.000 also think that this is what causes the auras. Yeah, 0:06:53.080 --> 0:06:54.599 now the auras. We I don't think we saw what 0:06:54.640 --> 0:06:59.159 that is. It's like a sort of a hallucinogenic visual 0:06:59.720 --> 0:07:04.720 thing that happens. Um lights lines blurry things, and they 0:07:04.760 --> 0:07:09.080 will or tunnel visions and they will proceed. It's a 0:07:09.080 --> 0:07:12.600 warning sign like migraines are coming. Maybe thirty minutes maybe 0:07:12.680 --> 0:07:15.920 and a day, but it's a coming. So that's what 0:07:15.960 --> 0:07:19.880 ours are, right, Um. And they think that that comes 0:07:19.880 --> 0:07:23.880 from this vasidilation in the brain, Like basically you're your 0:07:23.920 --> 0:07:26.800 brains just doing something screwy because all of a sudden 0:07:26.800 --> 0:07:29.080 there's a lot more blood flow and it maybe somebody's 0:07:29.080 --> 0:07:32.280 getting pressed on, somebody's getting a lot more oxygen's overworking. 0:07:32.320 --> 0:07:35.600 Who knows. Well. They can also cause leakage, actual leakage, 0:07:35.920 --> 0:07:40.000 right eventually they and that makes the tissue around the 0:07:40.080 --> 0:07:44.800 brain swell in your skull. So you have a lot 0:07:44.840 --> 0:07:49.800 more oxygen, you have leaking blood vessels, you have these auras, 0:07:49.880 --> 0:07:55.080 and you have in this cascade of heightened pain reception 0:07:55.560 --> 0:07:58.720 in the brain, and there is your migraine. As far 0:07:58.760 --> 0:08:00.680 as we understand it now, this is the most recent 0:08:01.240 --> 0:08:04.400 thinking of what migraines are. And some guy just told 0:08:04.440 --> 0:08:07.280 us this like thirty minutes thirty minutes ago. Hot off 0:08:07.280 --> 0:08:11.120 the presses. Uh. And since we mentioned triggers, we should 0:08:11.400 --> 0:08:15.320 talk about those for a second. They can depend on Uh. 0:08:15.600 --> 0:08:17.360 It's that they're not even the same for everyone. As 0:08:17.360 --> 0:08:19.600 Coup pointed out, they can be different things for him, 0:08:19.600 --> 0:08:22.200 like sometimes he said, caffeine will trigger it. Sometimes a 0:08:22.280 --> 0:08:24.520 lack of caffeine will trigger it. Right, It seems like 0:08:25.840 --> 0:08:29.760 the one constant in migraines is that they are they 0:08:29.760 --> 0:08:34.319 are triggered by change. Yeah, yeah, yeah, true, Yeah, that's 0:08:34.360 --> 0:08:38.679 really good things. Um so like food related um some 0:08:38.800 --> 0:08:45.240 say that caffeine, alcohol, cheese, gluten, nuts, soy msg. They 0:08:45.240 --> 0:08:49.760 can be triggers. Um smells, strong smells, strong smells like 0:08:49.800 --> 0:08:53.040 skraut onions, cologne. You got an elevator with somebody with 0:08:53.080 --> 0:08:55.480 really heavy perfume, you might get off the water with 0:08:55.520 --> 0:08:58.839 an aura happening. Yeah, and you're gonna be like, curse 0:08:58.920 --> 0:09:04.320 you snoop dog. Right. They can be behavioral, like we said, 0:09:04.360 --> 0:09:06.319 if you don't get enough sleep, or if you didn't 0:09:06.360 --> 0:09:09.600 eat on time, or if you're stressed, or maybe you 0:09:09.760 --> 0:09:13.360 just had sex or you're not having sex. Not having sex. Second, 0:09:13.400 --> 0:09:17.679 that's a real bummer. Um. Exercise, you exercise too hard 0:09:17.800 --> 0:09:21.200 or you don't exercise enough. So it's it's you never 0:09:21.240 --> 0:09:24.440 can't tell. That's what makes migraines such jerks. No, and 0:09:24.480 --> 0:09:26.360 this is we should say, like all of these are 0:09:26.600 --> 0:09:31.520 are like the characteristics the symptoms of all of the 0:09:31.559 --> 0:09:34.480 migraine sufferers in the world. Sure, for one person it 0:09:34.600 --> 0:09:39.080 might be Uh, they might be Uh no sex anchovy, 0:09:39.360 --> 0:09:44.679 um catheine just suffer. That's my Friday night dude. Right. 0:09:46.720 --> 0:09:49.920 There's also hormones. Yeah, and that's why they think that women, 0:09:50.280 --> 0:09:53.079 um might have more than men because of hormonal changes 0:09:53.080 --> 0:09:56.520 that women experience that men do not. And there's a 0:09:56.520 --> 0:10:01.800 lot of correlative evidence among up that implicate hormones in 0:10:01.800 --> 0:10:06.240 in in migraines like UM, migraines typically start after puberty 0:10:06.559 --> 0:10:09.839 and women right when the hormones really start kicking in 0:10:10.400 --> 0:10:14.160 UM they are very very rare. And women after menopause, 0:10:14.400 --> 0:10:18.760 when hormones are depleted, they actually can come about again 0:10:18.760 --> 0:10:23.360 in post mental puzzle women with hormone replacement therapy, UM, 0:10:23.400 --> 0:10:28.800 they can correlate with menstruation and and uh, when a 0:10:28.880 --> 0:10:34.120 woman becomes pregnant, has been pregnant, Uh, the migraines often 0:10:34.200 --> 0:10:36.880 subside or just go away completely. Right. So there's something 0:10:36.880 --> 0:10:38.760 to that. Oh yeah, there's a lot to it. The 0:10:38.800 --> 0:10:40.840 sad thing is that we have no idea what it is. 0:10:41.520 --> 0:10:43.480 You know, there's some poor schemo out there having a 0:10:43.559 --> 0:10:48.040 migraine right now and there's nothing anybody can do to 0:10:48.040 --> 0:10:50.400 help him right now. Well, maybe they're the dulcet tones 0:10:50.480 --> 0:10:53.280 of Josh Clark and his earbuds will make that go away? 0:10:54.840 --> 0:10:58.800 You think maybe because there are environmental factors that can 0:10:58.800 --> 0:11:00.679 make them happen, so maybe they can make them go away. 0:11:00.720 --> 0:11:03.240 I think that the dulcet tones of my voice was 0:11:03.320 --> 0:11:06.400 the cause of migraine, like a flashing light like remember 0:11:06.440 --> 0:11:09.280 the Nissan pulsar. Do you remember the break light went 0:11:10.559 --> 0:11:13.280 They actually had to slow the pattern because people were 0:11:13.320 --> 0:11:17.000 having seizures. Apparently that is probably an urban legend, but 0:11:17.080 --> 0:11:19.280 it's a good one that I remember from the eighties. 0:11:20.320 --> 0:11:23.520 That sounds very much like an urban legend. Loud noises, um, 0:11:23.559 --> 0:11:29.040 strong smells, like we said, weather pattern like rain, yeah, um, 0:11:29.080 --> 0:11:31.920 either when it's about to come on or it's just 0:11:32.120 --> 0:11:36.000 changed subsided, especially when it happens quickly e g. The summer, 0:11:37.080 --> 0:11:39.480 the change in barometric pressure. I suspect has a lot 0:11:39.600 --> 0:11:43.880 to do with that. Josh, what are the types of migraines? Well, Chuck, 0:11:43.960 --> 0:11:47.480 there is the classic migraine. We're gonna start with the second. First, 0:11:48.120 --> 0:11:52.040 there's the classic migraine that is preceded by an aura 0:11:52.160 --> 0:11:57.200 of some sort. The head pain comes on and uh, 0:11:57.480 --> 0:12:01.600 you're in big trouble. Right. There also chronic migraines, which 0:12:01.640 --> 0:12:06.080 are arguably among the worst, be more than fifteen a month. Yeah, 0:12:06.200 --> 0:12:12.000 that's basically a lot of classic a lot of classic migraines, right, um, 0:12:12.040 --> 0:12:16.280 common migraines. This is migraine pain with no aura. Yeah, 0:12:16.360 --> 0:12:19.719 no aura. Yeah, it's this is like a burger king 0:12:19.920 --> 0:12:24.319 of of horrible headaches, isn't it? Like however you want it? Yeah, 0:12:24.400 --> 0:12:27.439 but they did say that the common migraine though, while 0:12:27.520 --> 0:12:30.400 you may not have an aura, there might be feelings 0:12:30.400 --> 0:12:34.800 of euphoria or cognitive problems signaling like here it's a coming, right, 0:12:35.000 --> 0:12:37.760 which is so depressing if you think about it, like, man, 0:12:37.840 --> 0:12:44.520 I feel great and then you think crap. Uh. There 0:12:44.559 --> 0:12:49.520 are or I'm sorry, ocular migraines, which you get our 0:12:49.720 --> 0:12:54.360 symptoms without the pain of the headache, and they can 0:12:54.400 --> 0:12:57.920 just be like thirty minutes and they go away. So 0:12:57.960 --> 0:13:01.120 I don't understand if there's no pain and involved, and 0:13:01.160 --> 0:13:05.480 all you're getting is the hallucinogenic aura symptoms like what's 0:13:05.520 --> 0:13:10.400 the rub I mean imagine is distracting, but right, and 0:13:10.520 --> 0:13:12.880 this is probably a little concerning, like you're like, am 0:13:12.880 --> 0:13:16.760 I losing my mind? I have a brain tumor It's true. 0:13:16.800 --> 0:13:19.439 I'd like to hear from someone that suffers from ocular migraines. Actually, 0:13:19.440 --> 0:13:22.680 I wanted a better understanding of that firsthand. Abdominal migraines 0:13:22.720 --> 0:13:25.680 common in children, pretty awful. It's like all of the 0:13:25.679 --> 0:13:29.040 symptoms of a migraine except for the head pain. So 0:13:29.160 --> 0:13:34.040 you have sensitivity, a light nausea, vomiting um, screeching at 0:13:34.040 --> 0:13:36.440 anybody who tries to talk to you, that kind of thing, 0:13:36.920 --> 0:13:38.640 you know. The other thing Coop said is that he 0:13:39.360 --> 0:13:42.400 very much used to experience while he still experiences the nausea, 0:13:43.000 --> 0:13:45.840 but he said that he has gained such control over 0:13:45.920 --> 0:13:49.360 his vomit reflex that he has not thrown up since 0:13:49.480 --> 0:13:55.560 nine since Ghostbusters. He said, wow. Yeah, any also reference Seinfeld, 0:13:55.559 --> 0:13:57.520 of course, because I was gonna say that black and 0:13:57.520 --> 0:14:00.720 white cookie. That's right. H. Then there are cluster headaches, 0:14:00.720 --> 0:14:03.560 which we mentioned that men get more often, and they 0:14:03.559 --> 0:14:06.040 are not migraines, but they say they may be the 0:14:06.040 --> 0:14:09.200 most painful headache of all. But you remember and Donnie Darko, 0:14:09.320 --> 0:14:12.600 where Drew Barrymore tells everybody. There's some linguists who said 0:14:12.640 --> 0:14:15.280 that cellar door is the most beautiful phrase in the 0:14:15.280 --> 0:14:20.760 English language. Cluster headaches. Those two words they evoke. Do 0:14:20.800 --> 0:14:24.120 you know what a grape shot cannonball is? What it 0:14:24.160 --> 0:14:27.160 looks like. Okay, so I see one of those, But 0:14:27.360 --> 0:14:32.240 they're white and squishy balls that are connected together, almost 0:14:32.320 --> 0:14:38.120 like tumors, but they're real circular. They're spherical, right, and 0:14:38.160 --> 0:14:40.760 they start to like kind of drip and fall off, 0:14:40.760 --> 0:14:43.320 but they're constantly replaced. That's what comes into my mind's 0:14:43.320 --> 0:14:47.280 eye when I hear the word, the term cluster headache. Well, 0:14:47.320 --> 0:14:49.480 it sounds like it's that bad because it's a sudden 0:14:49.560 --> 0:14:54.160 explosion of pain after you've gone to sleep, Like you'll 0:14:54.160 --> 0:14:57.400 be asleep and you'll wake up with this happening very quickly, 0:14:57.440 --> 0:15:00.240 and it's usually behind one of your eyeballs. I think 0:15:00.280 --> 0:15:01.720 that's what my dad used to have, because he used 0:15:01.720 --> 0:15:04.360 to talk about it's right here and he pointed his 0:15:04.400 --> 0:15:07.960 eye and I would just laugh and say, Dad, you're 0:15:07.960 --> 0:15:12.960 so funny. So I'm getting that only in one way 0:15:13.040 --> 0:15:15.560 or another. The reason they call him cluster heaches is 0:15:15.600 --> 0:15:19.600 because they occur a bunch of times over the course 0:15:19.600 --> 0:15:21.560 of a couple of weeks. Then they'll go away, like 0:15:21.640 --> 0:15:25.520 for a year maybe then they'll come back in clusters 0:15:25.520 --> 0:15:28.840 in clusters over several weeks or whatever, and then go 0:15:28.880 --> 0:15:31.000 ahead with a thunderclap headache because I've never heard of that. 0:15:31.440 --> 0:15:37.840 Thunderclap headaches are um, very sudden, very severe. They're pretty 0:15:37.920 --> 0:15:40.880 much cluster headache, except they don't follow the same pattern. 0:15:41.280 --> 0:15:43.120 They just kind of come and go. They don't seem 0:15:43.200 --> 0:15:45.640 to follow any kind of pattern really, and it's like 0:15:45.840 --> 0:15:50.040 they're shorter. But um, if you get thunderclap headache, you 0:15:50.080 --> 0:15:52.160 may have blood pooling in your brain and you need 0:15:52.200 --> 0:15:54.320 to go see a doctor. Yeah, that's it's a pretty 0:15:54.320 --> 0:15:57.760 good sign that there's something very wrong with your brain. Um, 0:15:57.800 --> 0:16:01.280 And we should say cluster headaches and thunderclap headaches don't 0:16:01.360 --> 0:16:05.800 tend to occurrent families, whereas my graines to look at you, 0:16:07.320 --> 0:16:10.160 So how do you know? How do you get diagnosed 0:16:10.160 --> 0:16:13.120 with this? Basically you go in and say I think 0:16:13.320 --> 0:16:16.360 I have a brain tumor, and the doctor starts running 0:16:16.360 --> 0:16:20.840 tests on you using m ryes, cat scans, spinal taps, 0:16:21.640 --> 0:16:24.000 rule everything else. Everything else is ruled out, and they go, 0:16:24.240 --> 0:16:27.280 I think you might have migraines. But since we can't 0:16:27.280 --> 0:16:31.520 really explain migraines, well, I can't say for certain spinal tap. 0:16:31.560 --> 0:16:34.920 You ever had one of this? No, well, there's no 0:16:34.960 --> 0:16:37.440 reason that you should have, have you No, of course 0:16:37.480 --> 0:16:39.720 not well not, of course not people have them. But 0:16:40.160 --> 0:16:42.520 I just you know, you always laugh at spinal tap 0:16:42.560 --> 0:16:45.080 because the band and the movie, but you don't think 0:16:45.080 --> 0:16:48.120 about a needle going into your spine. That's what they're doing. 0:16:48.160 --> 0:16:50.640 They're tapping your spine like you tap a maple tree 0:16:50.680 --> 0:16:53.440 for syrup. And it's a big it's a big, long, 0:16:54.000 --> 0:16:57.640 like pretty heavy gauge. It's not like a tiny one. 0:16:57.760 --> 0:17:00.120 It's big. I'd need more than a local anist at 0:17:00.120 --> 0:17:04.720 it for that. My friend knock me out completely. I 0:17:04.760 --> 0:17:06.879 don't know that they can because they probably have to 0:17:06.920 --> 0:17:12.040 be um cognizant and aware and in control of your 0:17:12.040 --> 0:17:17.520 body so you don't move no, thank you. Uh. Some 0:17:17.600 --> 0:17:21.679 weird symptoms we talked about nausea and vomiting and stuff 0:17:21.720 --> 0:17:26.399 like that. You can also fart a lot. I've saw 0:17:26.440 --> 0:17:32.160 that flatulence problem. Flatulence a lot. You can be really thirsty, 0:17:32.320 --> 0:17:36.720 you can smell weird things that aren't there. You can 0:17:36.920 --> 0:17:42.040 think that you're appendages have grown in size, like my 0:17:42.240 --> 0:17:46.040 arm has grown. If they actually have, it's probably just overeating. 0:17:46.560 --> 0:17:49.639 If your arm gross. If your appendages grow in size, 0:17:50.480 --> 0:17:55.040 food cravings, temporary blindness, no fun. This is what Coop 0:17:55.040 --> 0:17:58.639 suffers from. And he still takes the time to do 0:17:58.680 --> 0:18:03.399 all those photoshop drops of us because he did a 0:18:03.400 --> 0:18:06.040 really good job with the Stepbrothers one. I mean, did 0:18:06.040 --> 0:18:07.639 you look at the detail in it? And they're all 0:18:07.680 --> 0:18:11.320 really good and so that was the peak. Yeah, so 0:18:12.280 --> 0:18:16.560 you got a migraine, Josh, what do you do well again? 0:18:17.400 --> 0:18:21.399 People people seem to treat themselves, or tend to treat themselves. 0:18:21.400 --> 0:18:23.880 They figure out what their triggers are, so they become 0:18:24.000 --> 0:18:33.800 very aware. If you're a um, chocolate sitar, uh, you 0:18:33.840 --> 0:18:38.040 shouldn't exercise, right. If that's you, that's my Friday night, 0:18:38.080 --> 0:18:41.320 you're gonna you're gonna stay away from exercise. You're going 0:18:41.359 --> 0:18:44.600 to stay away from sitar music, and you're gonna not 0:18:44.760 --> 0:18:47.359 eat chocolate, which sucks, but that's what you're gonna do. 0:18:47.440 --> 0:18:50.119 And so you're going to prevent it. Right, there's a 0:18:50.160 --> 0:18:53.399 cute treatment. There's preventative treatment. So you can prevent it, 0:18:53.960 --> 0:18:58.840 um by paying attention to what triggers. These things, paying 0:18:58.840 --> 0:19:03.200 attention to like if you get an aura, yeah, then 0:19:03.400 --> 0:19:07.439 you're acute. Treatment kicks in, maybe you are going to 0:19:07.480 --> 0:19:10.960 treat yourself acutely even before an ora kicks in. If 0:19:11.000 --> 0:19:14.119 if you expose yourself to one year triggers um and 0:19:14.160 --> 0:19:16.679 then if you if you do get the idea that 0:19:16.720 --> 0:19:19.640 you're going to have a migraine, you can often treat them. 0:19:19.680 --> 0:19:23.440 Like Coupe said, with you know a couple of eccrin migraines, 0:19:23.520 --> 0:19:27.879 which are really just um insides. Yeah, taylan a advilt 0:19:28.000 --> 0:19:31.720 non steroidal anti inflammatory drugs, right, and that's going to 0:19:31.800 --> 0:19:36.520 keep your brain from vasodilating supposedly. Yeah, and with ecceterrin, 0:19:36.560 --> 0:19:40.440 we should say that they specifically made the migraine UH 0:19:40.600 --> 0:19:45.800 pill and it's a combination of aspirin, ACTA, menefin, and caffeine, 0:19:46.080 --> 0:19:51.960 which migraine people said that works for me. You take 0:19:52.040 --> 0:19:55.840 these before head pain comes on. Once your head pain 0:19:55.920 --> 0:20:00.280 comes on, you need something stronger called SUMA trip hand 0:20:01.119 --> 0:20:05.560 summetric TAN, which is also called immatrix. Remember the immatrics 0:20:05.600 --> 0:20:08.760 adds with the semi coming at you. Yeah, yeah, right, 0:20:08.800 --> 0:20:15.080 Well apparently this stuff works after your head has started exploding. Yeah, 0:20:15.160 --> 0:20:18.720 it works pretty well from what most people say, right right. Um. 0:20:18.920 --> 0:20:21.200 I think also it's one of those things where there 0:20:21.200 --> 0:20:23.480 works for you or it doesn't. I guess if it 0:20:23.520 --> 0:20:25.240 works really well, you're gonna go all over the internet. 0:20:25.280 --> 0:20:27.720 Sound great, it is right, um, but I think it 0:20:27.800 --> 0:20:30.479 cannot work in people. But if you have nausea, if 0:20:30.480 --> 0:20:34.720 you have vomiting, fortunately for you there is uh summetrip 0:20:34.800 --> 0:20:39.560 tan I hope that's how you say it, um nasal sprays. Yeah, 0:20:39.880 --> 0:20:42.800 so you can't puke that back up. There's also injections. 0:20:42.840 --> 0:20:44.480 If you go at the hospital with the migraine, they're 0:20:44.480 --> 0:20:46.240 probably going to give you an injection of that. But 0:20:46.960 --> 0:20:49.360 as the author says in this article, you can get 0:20:49.400 --> 0:20:56.400 your very own immatrix injection. Yeah, preventative. They found that. Uh, 0:20:57.040 --> 0:20:59.879 and this is always so weird with me. For prescription drugs, 0:21:00.040 --> 0:21:03.560 they find the off label use. They're like, well, your 0:21:03.560 --> 0:21:07.520 blood pressure meds are stopping your migraines. That's cool. And 0:21:07.560 --> 0:21:11.920 there's a whole host of these antidepressants. Uh, Like I said, 0:21:11.920 --> 0:21:19.160 blood pressure medication, anihistamine, supro heptidine, cholesterol drugs, cardiovascular calcium 0:21:19.240 --> 0:21:22.400 channel blockers. They can all help with migraines with channel blockers. 0:21:22.440 --> 0:21:24.600 I wonder if that has to do with this, if 0:21:24.640 --> 0:21:29.199 it slows down the transmission of neurotransmitters because they go 0:21:29.359 --> 0:21:34.680 through ion channels. That's where the actual molecules go through. UM, 0:21:34.840 --> 0:21:36.359 So I wonder if that has something to do with it. 0:21:36.400 --> 0:21:39.520 And then obviously with like a blood pressure medicine that's 0:21:39.560 --> 0:21:44.000 going to keep vasodilation from occurring. UM. And then serotonin, 0:21:44.040 --> 0:21:47.520 they figured out that, like you said, antidepressants and other 0:21:47.600 --> 0:21:52.359 drugs that act on serotonin regulation or production have been 0:21:52.359 --> 0:21:56.520 shown to alleviate migraines or keep migraines from coming up 0:21:56.800 --> 0:21:59.880 on right, So serotonin has something to do with Sarah 0:21:59.880 --> 0:22:08.119 to owning hormones, anchovies, the crazy botox supposedly, Well, they 0:22:08.200 --> 0:22:11.600 just found that one of the weird side effects reported 0:22:11.760 --> 0:22:14.879 was that a fewer migraines and fewer headaches. But no 0:22:14.920 --> 0:22:17.200 one should go and get botox to relieve their migraines. 0:22:17.760 --> 0:22:20.960 We're not saying that. It's just we call that a sidebar, 0:22:22.040 --> 0:22:26.280 we do. Uh. And what about what Emily likes to 0:22:26.320 --> 0:22:31.960 call hokey pokey treatments and what other people call alternative medicine. Well, 0:22:32.000 --> 0:22:35.000 the one that jumped out at me is butter burr. Yeah, 0:22:35.000 --> 0:22:37.040 I've never heard of that. I hadn't either, but it's 0:22:37.080 --> 0:22:40.199 an herbal supplement. The problem is is um it may 0:22:40.320 --> 0:22:45.639 contain cancer causing compounds. So it's like, no, we're migraines 0:22:45.800 --> 0:22:50.280 or early death from cancer. I don't know, Rye Bo Flavian, 0:22:50.480 --> 0:22:55.200 eat your broccoli. Co enzyme Q tin supplements, cocute tin. 0:22:55.720 --> 0:22:59.160 Oh you know about cocute tin? Sure? Uh, fever few. 0:22:59.400 --> 0:23:04.480 It's an herbal supplement that apparently helps. It's an anti inflammatory. 0:23:04.880 --> 0:23:08.919 And then there are different things you can do like massage, 0:23:09.040 --> 0:23:12.719 breathing techniques, yoga, acupuncture has been said to help some folks. 0:23:13.200 --> 0:23:16.280 If you're into this alternative thing, I think whatever helps 0:23:16.960 --> 0:23:20.199 you know, well, Chuck, let's finish this. Let's bring this 0:23:20.240 --> 0:23:23.480 migraine to an in with famous people. Yeah. So apparently 0:23:23.520 --> 0:23:27.720 there is a theory of the migraine personality that people 0:23:27.760 --> 0:23:31.479 who have migraines are more driven, more creative. And then 0:23:31.520 --> 0:23:34.560 there's a lot of people who are driven in creative 0:23:34.680 --> 0:23:39.040 or were who had migraines, like we're before migraines killed them, 0:23:39.160 --> 0:23:47.080 right exactly, Virginia Wolf, Cervantes, uh, Nietzsche, Elvis, Freud, Monet, 0:23:47.440 --> 0:23:50.560 BEng It's also possible that all these people just happen 0:23:50.640 --> 0:23:54.960 to have migraines and we're creative famous, and there really 0:23:54.960 --> 0:24:00.680 isn't a migraine personality. You know. Percy Harvin, some Minnesota 0:24:00.720 --> 0:24:03.840 Vikings receiver played for the Florida Gators. Yeah, I was 0:24:03.920 --> 0:24:07.160 like to have a visceral reaction to that. Yeah, he's 0:24:07.160 --> 0:24:09.680 a migraine sufferer and he'll u I mean, it keeps 0:24:09.760 --> 0:24:11.280 him out of practice, out of games. He has to 0:24:11.320 --> 0:24:14.800 go basically home and seclude himself in a dark room. 0:24:14.880 --> 0:24:18.600 Apparently they're really really bad, despite the effect he played 0:24:18.600 --> 0:24:20.080 for Florida. I don't want to I don't want to 0:24:20.080 --> 0:24:24.800 wish that on anybody. Maybe Tim Tebow, maybe who's this 0:24:24.880 --> 0:24:31.280 Auburn coach? Yeah, yeah, what about him? Let's wish some 0:24:31.440 --> 0:24:37.159 migraines on them. You got anything else, I'm done, so KOPA. 0:24:37.160 --> 0:24:39.159 I hope buddy, you have a good Christmas and that 0:24:39.280 --> 0:24:44.200 your migraines. I hope we enlightened you some. He's probably like, no, yeah, 0:24:44.200 --> 0:24:46.240 I don't even know all this. Yeah, thanks, anyway, this 0:24:46.240 --> 0:24:48.040 would have been waiting two years for what how about this? 0:24:48.240 --> 0:24:52.600 Let's wish let's everybody just go and wish that the 0:24:52.800 --> 0:24:56.760 scientists will hurry up and cure migraines. Come about that. 0:24:57.880 --> 0:24:59.840 Do you want to learn more about migraines and see 0:24:59.840 --> 0:25:03.000 a picture of a brain getting hit by lightning? You 0:25:03.040 --> 0:25:05.960 can type that word in, Oh, we didn't talk about 0:25:06.000 --> 0:25:09.680 the word migraine, Chuck. The etymology of the word migraine, 0:25:09.720 --> 0:25:14.080 I should say, uh, comes from two words hem acrania 0:25:14.320 --> 0:25:17.160 half a brain, remember it only hits part of your 0:25:17.160 --> 0:25:21.520