WEBVTT - Ozempic with Dr. Ehsan Ali 0:00:01.000 --> 0:00:06.000 This is the most dramatic podcast ever and iHeartRadio podcast. 0:00:07.240 --> 0:00:09.559 Chris Harrison and Lauren Zema coming to you from Well, 0:00:09.600 --> 0:00:11.559 I'm in Austin, Texas, Elsie, where are you? 0:00:11.920 --> 0:00:15.840 I'm in Delray Beach, Florida, visiting my little sister. As 0:00:15.880 --> 0:00:18.840 we've mentioned many times, it's our Divide and Conquer holidays. 0:00:19.600 --> 0:00:21.919 We have the kids at our house in Austin for Christmas, 0:00:21.960 --> 0:00:23.799 so I wanted to go see my family in Florida 0:00:23.840 --> 0:00:25.520 for like a pre Christmas. 0:00:25.520 --> 0:00:27.640 But I love seeing you on Zoom, Honey. It's kind 0:00:27.640 --> 0:00:29.600 of like, Oh, I miss you, and there you are. 0:00:29.400 --> 0:00:33.599 And you look good too. So last week we were 0:00:33.640 --> 0:00:36.720 talking about oh zimpic, Oprah kind of blew the lid 0:00:36.760 --> 0:00:39.040 on this thing. Well, I mean Oprah didn't blow the 0:00:39.080 --> 0:00:41.360 lid on this thing, but she kind of kept this 0:00:41.440 --> 0:00:44.280 conversation going. Obviously it's been going for quite some time, 0:00:44.760 --> 0:00:48.200 and you and I had a deep discussion about Oprah 0:00:48.240 --> 0:00:52.840 and the ladies in our neighborhood, the ladies in every neighborhood, 0:00:53.200 --> 0:00:55.800 and we said we would dive deeper into this. So 0:00:56.360 --> 0:00:59.000 we are bringing on a very special guest today, doctor 0:00:59.160 --> 0:01:03.720 Aeson All, a board certified in internal medicine. He's also 0:01:03.720 --> 0:01:09.080 completed a fellowship training in geriatric medicine, currently practicing as 0:01:09.080 --> 0:01:12.039 a physician in Beverly Hills. That is going to shed 0:01:12.080 --> 0:01:14.039 a lot of light on this. I can only imagine 0:01:14.120 --> 0:01:16.200 what's going on in Beverly Hills with ozempic and all 0:01:16.200 --> 0:01:19.559 these weight loss drugs. Very unique practice because he's also 0:01:20.000 --> 0:01:23.840 a world renowned doctor at Cedar Sinaide Medical Center, also 0:01:23.880 --> 0:01:27.039 in a spare time volunteering at free medical clinics. So 0:01:27.680 --> 0:01:34.640 if anybody is equipped to talk about this weight loss praze, 0:01:35.000 --> 0:01:37.920 it's doctor asan Ali and we are very happy to 0:01:37.920 --> 0:01:38.720 have him on the show. 0:01:39.440 --> 0:01:41.280 Well, I'm so excited to get into it because our 0:01:41.319 --> 0:01:43.840 producer Kendall just mentioned a weight loss drug I hadn't 0:01:43.880 --> 0:01:46.520 even heard of. I've heard of ozempic. I've heard of 0:01:46.560 --> 0:01:49.200 Wagovia if I have this right, so I might need 0:01:49.280 --> 0:01:52.680 to be corrected, but I believe Wagovia is approved just 0:01:52.840 --> 0:01:56.880 for weight loss. Ozempic's still technically supposed to be used 0:01:56.960 --> 0:02:00.880 to treat diabetes, that was its original intention. Just mentioned 0:02:00.920 --> 0:02:04.560 one called Manjaro, So there's there's weight loss drugs out there. 0:02:04.560 --> 0:02:05.440 I haven't even heard of. 0:02:05.760 --> 0:02:07.640 I'm so excited to talk to him because, like you 0:02:07.680 --> 0:02:10.000 just said, Oprah, she didn't say which one, but she 0:02:10.120 --> 0:02:13.000 did feel that she is on a weight loss drug 0:02:13.040 --> 0:02:15.679 and she really owned it and said, Look, I've publicly 0:02:15.720 --> 0:02:19.040 struggled with my weight loss for years and something like 0:02:19.080 --> 0:02:22.240 this feels like a relief. So I just I feel 0:02:22.240 --> 0:02:25.280 like Oprah saying that could maybe turn the tide on 0:02:25.320 --> 0:02:27.960 some of the backlash people feeling like these are being misused. 0:02:28.000 --> 0:02:30.280 So I'm excited to get into all of it with him, 0:02:30.639 --> 0:02:33.799 and he is on with us now, Doctor Ellie, I 0:02:33.880 --> 0:02:36.400 got to tell you, I don't know if my mom's 0:02:36.560 --> 0:02:41.800 ever been more excited for a podcast guest. I feel like, 0:02:42.000 --> 0:02:45.240 oh zeenpic and weight loss drugs are the topic at 0:02:45.240 --> 0:02:49.760 the top of every chat amongst women ages maybe younger, 0:02:49.760 --> 0:02:51.760 but for me, I'm in my thirties, like thirties and 0:02:51.800 --> 0:02:52.640 above that. 0:02:52.720 --> 0:02:53.080 I know. 0:02:53.800 --> 0:02:57.680 How would you say that this weight loss drug craze 0:02:57.720 --> 0:03:00.560 compares to other drugs that have hit them, like I've 0:03:00.560 --> 0:03:01.760 heard it be compared. 0:03:01.400 --> 0:03:03.920 To like when Viagra dropped. Is it even bigger than that? 0:03:04.480 --> 0:03:08.119 I feel like it's even bigger because this medication applies 0:03:09.040 --> 0:03:13.240 not just to like one of demographic. It's men, women, young, old, 0:03:13.720 --> 0:03:16.120 It's a significant amount of the population. So I feel 0:03:16.120 --> 0:03:19.080 like it's even surpassed medications like viager. It's probably one 0:03:19.120 --> 0:03:22.640 of the most popular medications ever since in my career, 0:03:22.720 --> 0:03:24.240 like the past twenty years that I've seen. 0:03:25.200 --> 0:03:27.640 Would it be safe to say this could be the 0:03:27.680 --> 0:03:30.799 biggest medication raise ever? 0:03:31.480 --> 0:03:36.960 I believe so, yes, absolutely absolutely. I mean, weight loss 0:03:37.000 --> 0:03:39.520 has been something that people have struggled with for the 0:03:39.560 --> 0:03:42.280 longest time, and there's never been a medication that's actually 0:03:42.320 --> 0:03:46.320 been extremely effective. You know, there was there's stimulant based 0:03:46.400 --> 0:03:48.400 medications like fen fend back in the day. You may 0:03:48.480 --> 0:03:51.280 or may not even remember, but it was stimulant based 0:03:51.280 --> 0:03:54.320 and then people were like overdosing having heart attacks, and 0:03:54.360 --> 0:03:56.720 then it got banned and there really wasn't anything out. 0:03:56.920 --> 0:03:59.960 So there's never been anything like this given people great 0:04:00.040 --> 0:04:03.400 it results with minimal risks, so it's kind of a 0:04:03.480 --> 0:04:04.200 huge breakthrough. 0:04:04.560 --> 0:04:07.440 I mean, I am so curious about all this. I'm 0:04:07.480 --> 0:04:09.880 so perplexed. I think everybody is. Even the people that 0:04:09.920 --> 0:04:13.120 are on it are probably still curious about everything going on. 0:04:13.880 --> 0:04:17.520 How many drugs are there, Like Lauren said, Wegovia, there's 0:04:18.839 --> 0:04:21.919 obviously ozempic, and is there one that's better than the 0:04:21.960 --> 0:04:23.039 other that you're finding is. 0:04:23.360 --> 0:04:25.560 Just heard about Manjaro. I didn't know about that one. 0:04:25.880 --> 0:04:29.400 Oh yeah, So you know the three now four most 0:04:29.400 --> 0:04:32.480 popular one, there's Ozembic, which came out initially had tons 0:04:32.520 --> 0:04:35.799 of advertising, our celebrities talked about it. It's very popular. 0:04:36.400 --> 0:04:38.400 Then came out with Govi, which is just a different 0:04:38.440 --> 0:04:42.160 brand of ozembic with the same active ingredient. Those two work, 0:04:42.360 --> 0:04:44.560 but really the one that's been shown to be even 0:04:44.680 --> 0:04:49.040 better is this genre that came out shortly after ozembic. 0:04:49.080 --> 0:04:51.080 And the reason it works better is because it acts 0:04:51.080 --> 0:04:54.680 on more receptor than your body compared to ozembic or rigovie. 0:04:54.720 --> 0:04:57.480 And I've had several patients who've done both. They've all 0:04:57.520 --> 0:04:59.760 said that they've had significantly better results with. 0:04:59.800 --> 0:05:02.600 The And then you said there's a fourth one, and. 0:05:02.600 --> 0:05:07.400 So Munjaro has only been FBA approved for diabetes, but 0:05:07.520 --> 0:05:10.359 recently it got the approval by the FDA for weight loss. 0:05:10.360 --> 0:05:12.880 And this just happened I think two three weeks ago. 0:05:14.000 --> 0:05:16.000 But for people who are going to use Manjaro for 0:05:16.120 --> 0:05:19.080 weight loss as opposed to diabetes, it's now being sold 0:05:19.160 --> 0:05:22.680 under a different name. It's called it just came out. 0:05:23.000 --> 0:05:26.600 What what was that zip bound bound? 0:05:27.200 --> 0:05:30.760 Yeah, better than the bound, gotcha? But so z that 0:05:30.960 --> 0:05:34.040 bound mnjaro, both which are the same thing, are much 0:05:34.200 --> 0:05:37.119 more effective than ozeen vic or withob's. 0:05:37.000 --> 0:05:39.680 And and dumb this down for people that did not 0:05:39.800 --> 0:05:45.160 go to med school. And what exactly is manjaro doing 0:05:45.400 --> 0:05:46.159 to my body? 0:05:47.040 --> 0:05:52.240 So? Okay, so ozembic, we go VI, munjaro. They all 0:05:52.320 --> 0:05:54.479 act on this receptor in your brain called a g 0:05:54.680 --> 0:05:58.279 LP okay, and then mnjaro acts on some other receptors 0:05:58.320 --> 0:06:02.640 as well. It's telling your body that you're not hungry, 0:06:02.800 --> 0:06:06.159 so you feel like you're just full constantly and you 0:06:06.200 --> 0:06:08.320 don't want to eat, And it helps control your cravings. 0:06:08.320 --> 0:06:11.040 It helps prevent binge eating. And then when you do 0:06:11.240 --> 0:06:15.119 eat normally, your stomach would expand to accommodate that extra food. 0:06:15.480 --> 0:06:18.599 It helps minimize that expansion of the stomach, so you 0:06:18.640 --> 0:06:22.039 eat a whole lot less as well, gotcha. So that's 0:06:22.120 --> 0:06:24.599 one aspect to it. And then it helps optimize and 0:06:24.640 --> 0:06:28.600 control your insulin levels. So by preventing like insulin spikes, 0:06:29.080 --> 0:06:32.279 this thing can cause weight gain, it helps prevent that 0:06:32.440 --> 0:06:35.640 as well. So that's the two main ways that it's working. 0:06:37.800 --> 0:06:41.839 So there's these different options available. How do you make 0:06:41.880 --> 0:06:45.120 the choice on who gets which? Or would you mostly 0:06:45.160 --> 0:06:46.800 give people zet bound. 0:06:47.360 --> 0:06:49.680 So just like right now, I tell him, listen, these 0:06:49.680 --> 0:06:51.800 are the three or four medications that are out. This 0:06:51.880 --> 0:06:53.760 is how this one works. This is how this one works. 0:06:53.760 --> 0:06:57.160 From my experience, when Jarro works the best. So I 0:06:57.200 --> 0:06:59.800 always recommend Njarro, but with a lot of times to 0:06:59.839 --> 0:07:02.120 come down to his cost, because they're all very expensive 0:07:02.800 --> 0:07:06.359 and most insurances aren't covering it, especially if you're not diabetic, 0:07:07.560 --> 0:07:10.120 or even if you meet the criteria you have it filmore. 0:07:10.160 --> 0:07:11.880 But the's a lot of insurances aren't covering it, so 0:07:11.880 --> 0:07:15.520 it comes down to what insurance will cover or every 0:07:15.560 --> 0:07:17.760 now and then there's a coupon available and somebody that's 0:07:17.760 --> 0:07:19.480 want to pay for the price. It comes down to price. 0:07:19.480 --> 0:07:22.000 But I always kind of tell people when Jaro does 0:07:22.080 --> 0:07:25.760 work the best, So that would be my recommendation to somebody. 0:07:26.000 --> 0:07:30.040 Much like gas in California, which is eighty times higher 0:07:30.040 --> 0:07:33.520 than the rest of the world, I'm guessing these drugs 0:07:33.560 --> 0:07:36.920 are pretty expensive in Beverly Hills. If I'm going on Manjaro, 0:07:38.040 --> 0:07:39.120 what's the cost. 0:07:39.720 --> 0:07:42.240 I believe so, depending on which pharmacy you go to, 0:07:42.360 --> 0:07:45.119 it's anywhere from twelve hundred a month to fifteen hundred 0:07:45.120 --> 0:07:45.400 a month. 0:07:45.520 --> 0:07:46.760 Holy Calenda. 0:07:46.880 --> 0:07:49.120 The price is pretty much the same across the country, 0:07:49.120 --> 0:07:51.560 because I have patients who are in New York for more, 0:07:51.600 --> 0:07:54.040 in Connecticut wherever. They've all kind of told me the 0:07:54.080 --> 0:07:56.240 same thing somewhere in that ballpark. 0:07:56.840 --> 0:07:59.280 Is that a daily dose? Is it a daily shot? 0:07:59.520 --> 0:08:02.200 It's a once a week shot that you just do 0:08:02.280 --> 0:08:03.080 underneath the game. 0:08:03.760 --> 0:08:06.080 And so do most people self medicate or do they 0:08:06.080 --> 0:08:08.400 come into your clinic and get a quick shot? Is it, 0:08:08.440 --> 0:08:10.280 you know, just a very simple shot to the arm 0:08:10.360 --> 0:08:11.120 or the butt. 0:08:11.360 --> 0:08:14.560 It's super easy. They come in, we evaluate them, we 0:08:14.680 --> 0:08:16.920 prescribe it. I send it to their pharmacy, whether it's 0:08:16.920 --> 0:08:19.680 a CBS right Aid watering wherever they go pick it 0:08:19.760 --> 0:08:21.960 up to get a one month supply. I teach them 0:08:21.960 --> 0:08:24.400 in the office with a demonstration pen, like how to inject. 0:08:24.960 --> 0:08:27.240 It's so easy, like you know, anybody could do it, 0:08:27.280 --> 0:08:29.400 and people will just do it at home on their own. 0:08:29.760 --> 0:08:31.440 And then they follow up every month with us just 0:08:31.440 --> 0:08:32.440 to see how things you're going. 0:08:33.280 --> 0:08:35.959 If we've learned anything over the last several years. It's 0:08:36.000 --> 0:08:39.959 that we can't really worry or think that the pharmaceutical 0:08:39.960 --> 0:08:42.760 companies are going to look out for our best needs. 0:08:43.120 --> 0:08:45.280 So we have to care and think about the doctors. 0:08:45.640 --> 0:08:48.600 So talking to a doctor that probably deals with this 0:08:48.679 --> 0:08:51.320 all the time because you're a Beverly Hills. So is 0:08:51.400 --> 0:08:53.440 this overall? Is it a good thing? 0:08:54.280 --> 0:08:55.800 Is it a good thing? There's two ways to look 0:08:55.840 --> 0:08:57.880 at it. Now for people who have been struggling, and 0:08:57.920 --> 0:08:59.800 I see a lot of patients who come in and 0:09:00.040 --> 0:09:03.840 and you know, whether you're somebody who's middle aged or 0:09:03.880 --> 0:09:06.480 you know, postmenopausal, and you're struggling with your weight and 0:09:06.480 --> 0:09:09.080 you've done everything, you're dieting, you have a personal trainer, 0:09:09.600 --> 0:09:11.439 you just can't get the weight off, weight off. Yes, 0:09:11.520 --> 0:09:14.360 this is a good thing for them. But then there's 0:09:14.400 --> 0:09:15.960 the other hand, there's people who don't need to be 0:09:16.040 --> 0:09:18.559 on it who are getting access to it, and they're 0:09:18.559 --> 0:09:21.840 they're kind of getting carried away and it's bad for them. 0:09:22.240 --> 0:09:24.199 And I've seen that as well. People you know, I'll 0:09:24.240 --> 0:09:25.719 get patients will come in, they lose the weight and 0:09:25.760 --> 0:09:28.880 they're like, you know what, I don't keep going. So 0:09:29.679 --> 0:09:31.960 it's kind of tricky, you know, it's meant to be 0:09:32.000 --> 0:09:34.680 a good thing. But with everything that's good, there always 0:09:34.679 --> 0:09:36.840 tends to be some downfall with that as well. 0:09:37.600 --> 0:09:40.360 Well, this we're kind of getting really into what I 0:09:40.480 --> 0:09:42.880 wanted to have you on for which and you know 0:09:42.920 --> 0:09:45.120 you said a minute ago minimal risks, and Chris is 0:09:45.160 --> 0:09:47.320 asking like is it a good thing? I mean, I 0:09:47.360 --> 0:09:50.520 think this is the real sort of point we're getting 0:09:50.520 --> 0:09:53.160 to now, this tipping point of like who is it 0:09:53.240 --> 0:09:53.640 safe for? 0:09:53.840 --> 0:09:56.280 When is it safe? Are we all going to be 0:09:56.320 --> 0:09:57.800 on it? At one point? Like I want to get 0:09:57.840 --> 0:09:59.280 into all that, but first I do I want to 0:09:59.280 --> 0:10:01.640 ask you a little bit gossipy question. I mean, I 0:10:01.640 --> 0:10:04.480 don't need you can name names, but you are. 0:10:04.400 --> 0:10:09.040 Known as a concierge doctor in Beverly Hills, incredibly reputable. 0:10:09.720 --> 0:10:13.880 What percentage of people do you think in Beverly Hills 0:10:14.040 --> 0:10:16.120 at this point are on weight loss medication? 0:10:16.960 --> 0:10:24.120 I would say, especially amongst women, probably seventy percent. 0:10:24.880 --> 0:10:31.560 Wow, well yeah, I thought maybe fifty percent. It's almost 0:10:31.600 --> 0:10:33.120 three quarters of the population. 0:10:33.400 --> 0:10:37.400 It's very very popular, you know, if not seventy, like 0:10:37.440 --> 0:10:39.200 you know, sixty five plus for sure? 0:10:39.360 --> 0:10:39.560 Yes? 0:10:39.840 --> 0:10:43.280 And do all those women need to be on it? 0:10:43.400 --> 0:10:45.520 Or could they be losing weight without it. 0:10:46.600 --> 0:10:49.120 I don't think all those women need to be on it. 0:10:49.520 --> 0:10:51.440 You know, there are women that could lose the weight 0:10:51.559 --> 0:10:55.480 without having to be on it. So no, I don't 0:10:55.480 --> 0:10:56.600 think it's all I. 0:10:56.640 --> 0:10:59.120 Mean, the idea of this drug was the you know, 0:10:59.520 --> 0:11:02.920 help with you know when you have the catchphrase the comorbidity. 0:11:03.040 --> 0:11:06.160 So that is that was the impetus for these drugs 0:11:06.160 --> 0:11:09.560 in the first place. Obviously, now you see people, hey, 0:11:09.679 --> 0:11:12.880 I need to lose ten before my wedding. Yeah, that's 0:11:12.880 --> 0:11:15.200 a very slippery slope because, like you said, there are 0:11:15.280 --> 0:11:17.319 ripple effects to everything that you. 0:11:17.360 --> 0:11:22.120 Take, absolutely absolutely, and so it is also a newer medication. 0:11:22.280 --> 0:11:24.600 So you know, even though from what we're being told 0:11:25.120 --> 0:11:28.480 it's safe and I haven't myself seen any severe complications, 0:11:29.000 --> 0:11:31.360 you still don't know what may happen ten years down 0:11:31.360 --> 0:11:34.920 the road. So you know, it's something that we have 0:11:34.960 --> 0:11:37.200 to be careful with in that aspect too. And so 0:11:37.320 --> 0:11:39.160 people who are trying to take it to lose ten 0:11:39.200 --> 0:11:41.400 pounds before their wedding or a photo shoot or a 0:11:41.480 --> 0:11:45.120 music video or the trip to Hawaii, like they shouldn't 0:11:45.160 --> 0:11:47.240 be on it. 0:11:56.840 --> 0:11:58.800 Okay, Well, what you just said is something really big 0:11:59.000 --> 0:12:00.840 is that's something I wanted to ask, what do we 0:12:00.920 --> 0:12:04.640 really know long term? To what extent has this been studied, 0:12:04.840 --> 0:12:08.560 these drugs being used for weight loss in terms of yeah, 0:12:08.600 --> 0:12:10.600 where your body might be, Like, do we know long 0:12:10.679 --> 0:12:13.080 term side effects or is that research not even been done? 0:12:13.520 --> 0:12:17.320 You know? According to what the pharmaceutical company tells us, 0:12:17.520 --> 0:12:20.600 they say during trials, the biggest thing that they saw 0:12:20.760 --> 0:12:23.800 was risk of thyroid cancer that they saw in roadings 0:12:23.840 --> 0:12:26.800 and rats. They say in humans, like, if you've had 0:12:26.800 --> 0:12:28.880 a history of thyroid cancer, you probably should just stay 0:12:28.880 --> 0:12:32.319 away from it. But like Chris had said, pharmaceutical companies 0:12:32.320 --> 0:12:34.720 don't necessarily have our best interests. They're out there to 0:12:34.760 --> 0:12:37.760 make money. So if there's information out there that's not 0:12:37.840 --> 0:12:40.920 being told to us, that's very much possible. Or whether 0:12:41.960 --> 0:12:44.079 it's too early to say if there's any long term risk, 0:12:44.200 --> 0:12:46.000 that's also something to be aware of as well. 0:12:46.280 --> 0:12:49.200 Is it potentially more dangerous if you're just taking it 0:12:49.280 --> 0:12:51.200 for a little bit of weight loss, or is it 0:12:51.240 --> 0:12:54.640 like the potential side effects are equal across the board, you. 0:12:54.640 --> 0:12:57.480 Know, So typically with medications, the longer you stay on it, 0:12:57.600 --> 0:13:01.920 the longer, the higher the risk of complications. So in 0:13:01.960 --> 0:13:05.240 this situation. I feel like people are taking it unnecessarily 0:13:05.320 --> 0:13:07.720 and take it long term are probably at higher risk 0:13:07.880 --> 0:13:10.600 or potential publications that we may not be aware of. 0:13:12.040 --> 0:13:15.440 So the yo yo uh you're saying is better like 0:13:15.440 --> 0:13:16.760 someone who just gets on it for a couple of 0:13:16.800 --> 0:13:18.319 weeks then gets off of it. 0:13:18.760 --> 0:13:22.000 That's my assumption. You know, even though they shouldn't be 0:13:22.040 --> 0:13:24.160 on it in the first place, they don't need to 0:13:24.160 --> 0:13:25.959 be on it, right, But if they're only going to 0:13:26.040 --> 0:13:29.439 be on it a shorter period of time, typically with medications, 0:13:29.880 --> 0:13:31.560 you're putting your body at less risk. 0:13:32.080 --> 0:13:33.840 You said something about the safety of it, and that 0:13:34.000 --> 0:13:36.080 you know early on. You know, we don't know the 0:13:36.080 --> 0:13:38.800 long term effects, but what about short term effects? Have 0:13:39.000 --> 0:13:41.120 you dealt with this with any of your clients? The 0:13:41.120 --> 0:13:45.079 blockage we've heard about and even deaths have been reported 0:13:45.760 --> 0:13:50.600 and not maybe one hundred percent linked, but people feel 0:13:50.640 --> 0:13:53.959 pretty certain that it was linked to these drugs. The 0:13:54.000 --> 0:13:58.160 bowel blockages and other issues that they've had so great. 0:13:58.160 --> 0:14:01.240 You know, we've all heard about those. In my experience 0:14:01.240 --> 0:14:03.280 in the past two years of prescribing it, ever since 0:14:03.320 --> 0:14:06.080 it's bout in the market, I do experience a lot 0:14:06.080 --> 0:14:09.800 on the common side effects like nausea, constipation, harper and 0:14:09.840 --> 0:14:13.240 some hair loss, fatigue. I have not witnessed or encounter 0:14:13.360 --> 0:14:15.960 indications from had any of the more serious side effects 0:14:16.160 --> 0:14:17.679 like blockages or anything. 0:14:17.600 --> 0:14:18.440 But you've heard of those. 0:14:18.960 --> 0:14:19.800 I have heard of them. 0:14:20.360 --> 0:14:23.360 I'm still processing that seventy percent, doctor Alia. 0:14:24.400 --> 0:14:26.920 I know, babe, don't you think that it's seventy percent 0:14:26.920 --> 0:14:29.480 of our neighborhood? And I mean everyone we run into, 0:14:29.600 --> 0:14:32.000 and you know, Lauren said it's people her age whatever. 0:14:32.080 --> 0:14:35.160 I'm like, I was with two dudes eating breakfast tacos 0:14:35.160 --> 0:14:36.960 the other day and we were talking about it. So 0:14:37.120 --> 0:14:41.400 it really has, if not become a part of our lives, 0:14:41.400 --> 0:14:44.160 it's definitely captured our conversation, our imagination. 0:14:44.320 --> 0:14:46.880 Here's what I said to Chris the other day, doctor Alie. 0:14:46.880 --> 0:14:49.600 I was like, look, we did just get married, and 0:14:50.840 --> 0:14:52.960 I was a friend of mine was like, yeah, if 0:14:53.000 --> 0:14:55.160 you want to get Gogovia, I can get you on it. 0:14:55.680 --> 0:14:58.080 And I was like, no, I just can't. Like for me, 0:14:58.240 --> 0:15:00.760 I can't bring myself to do that now. Like I'm 0:15:00.760 --> 0:15:03.720 just going to work out and like, well, really watch 0:15:03.760 --> 0:15:06.200 what I eat, really cut back on alcohol and I 0:15:06.280 --> 0:15:08.600 ended up losing you know, like ten pounds before the wedding, 0:15:08.640 --> 0:15:09.600 which I wanted to do. 0:15:10.920 --> 0:15:11.480 Thank you. 0:15:11.680 --> 0:15:16.920 But what scares me at this point is even if 0:15:16.920 --> 0:15:20.120 you're somebody who's like eating really well and really watching 0:15:20.160 --> 0:15:23.000 what they eat and all that, it seems like even 0:15:23.120 --> 0:15:25.160 those people are now getting on. 0:15:25.160 --> 0:15:26.200 Weight loss medication. 0:15:26.880 --> 0:15:30.640 So if I'm a healthy, fit person, as time goes 0:15:30.640 --> 0:15:32.560 by and everybody's on this, am I going to like 0:15:32.760 --> 0:15:36.520 start to look over weight because everyone else is on 0:15:37.040 --> 0:15:39.560 weight loss drugs? Because seventy percent of people are Do 0:15:39.600 --> 0:15:40.720 you see what I'm saying with this? 0:15:41.800 --> 0:15:43.720 Am I going to look fat. 0:15:43.400 --> 0:15:45.800 When I'm it's a new boob job. 0:15:48.080 --> 0:15:50.240 That's a good way of looking at it, Chris. But yeah, 0:15:50.240 --> 0:15:52.840 that's definitely something that may happen down the line if 0:15:52.880 --> 0:15:55.200 more and more people are on it and it's becoming 0:15:55.200 --> 0:15:58.040 more easily available too. For the longest time to shortages 0:15:58.360 --> 0:16:00.960 couldn't get it, and now there's much of a shortage, 0:16:01.000 --> 0:16:04.160 it's lass better than it was before, So that might 0:16:04.200 --> 0:16:06.000 be an issue down the line. You know, the new 0:16:06.080 --> 0:16:09.840 normal healthy might be overweight a four inches of the 0:16:09.880 --> 0:16:12.440 women who want to be like railed, skinny or real. 0:16:12.600 --> 0:16:14.840 Okay, so let me ask you about the other fear 0:16:15.280 --> 0:16:18.160 because you know a lot of these spears are just aesthetic. Yeah, 0:16:18.280 --> 0:16:21.480 I've heard of ozempic butt that you can get a 0:16:21.520 --> 0:16:24.640 saggy butt. I've heard of ozembic face that your face 0:16:24.680 --> 0:16:27.760 can look saggy, that you can lose muscle and then 0:16:27.760 --> 0:16:30.080 your body just overall doesn't look the way you want. 0:16:30.560 --> 0:16:33.160 How real are those risks? Do you see that? And 0:16:33.440 --> 0:16:34.400 is there a way to avoid it? 0:16:34.440 --> 0:16:36.000 If it happens? What causes it? 0:16:36.560 --> 0:16:40.120 So o zombic phase or ozombic butt that typically happens 0:16:40.120 --> 0:16:42.480 and people who are very heavy to begin with and 0:16:42.520 --> 0:16:45.480 have lost a lot of weights, and also people who 0:16:45.480 --> 0:16:49.000 are a little bit older, so their skin quality isn't 0:16:49.040 --> 0:16:51.400 as good or like the elastic quality good, so it 0:16:51.440 --> 0:16:54.200 doesn't really kind of shrink as with the weight loss. 0:16:54.240 --> 0:16:57.160 So I feel like that would happen with people who 0:16:57.200 --> 0:17:01.200 would wait rapidly, even with just died and exercise. I 0:17:01.240 --> 0:17:04.000 don't see it that often, and you have to lose 0:17:04.040 --> 0:17:06.440 a significant amount of weight for that to happen. That 0:17:06.440 --> 0:17:09.440 would probably happen in like you're let's say fifty year 0:17:09.480 --> 0:17:12.800 old person who lost maybe like forty fifty pounds. We 0:17:12.920 --> 0:17:15.640 have all this extra week. I don't really see it. 0:17:15.600 --> 0:17:18.240 That often, okay, because the headlines are making it seem 0:17:18.320 --> 0:17:20.879 like it's all over and now we're all going to 0:17:20.960 --> 0:17:23.520 have Saggy's a big case, okay. 0:17:23.600 --> 0:17:27.160 Doctor Elie. Something that Lauren just touched on in that question, 0:17:27.200 --> 0:17:30.000 I kind of want to follow up on where is 0:17:30.040 --> 0:17:35.480 the weight coming from? Where's the weight loss? Is it muscular? 0:17:36.440 --> 0:17:39.239 Is it just fat? Is this you know our end? 0:17:39.320 --> 0:17:42.600 Are these different medicines targeting different things? And obviously, again 0:17:43.119 --> 0:17:45.600 if you are a you know, average woman, average man, 0:17:45.760 --> 0:17:48.280 you're healthy for the most part, and you go on 0:17:48.320 --> 0:17:50.560 these drugs, where is it coming from? And is it 0:17:50.600 --> 0:17:51.080 worth it? 0:17:52.480 --> 0:17:56.639 So I have seen patients lose both fat as well 0:17:56.720 --> 0:17:59.560 as muscle masks, but I will say, you're like most 0:17:59.600 --> 0:18:02.840 of the weight that people are losing his muscle mass. Interesting, 0:18:04.040 --> 0:18:07.240 but you know they also are losing like extra like 0:18:07.320 --> 0:18:10.240 fatty tissue or you know that's soft kind of like 0:18:10.960 --> 0:18:13.720 handle around their waist. So it works on both, but 0:18:13.880 --> 0:18:15.840 a large portion of it is muscle mass. 0:18:16.640 --> 0:18:19.280 I'm curious then if you're working out, Uh, safe for 0:18:20.040 --> 0:18:22.160 man or woman doesn't really matter. But if you are, 0:18:22.240 --> 0:18:23.720 you like to be fit and you want to be 0:18:24.040 --> 0:18:28.080 you know cut, this isn't the cut medicine, like, because 0:18:28.280 --> 0:18:32.320 if you're losing that muscle, Like, I'm curious the how 0:18:32.320 --> 0:18:35.080 the balance of the scales work of I'm working out 0:18:35.119 --> 0:18:38.879 really hard, I'm on one of these drugs. How have 0:18:38.960 --> 0:18:41.720 you seen that even itself out? 0:18:41.920 --> 0:18:44.200 So let's just say, let's you know, just the kind 0:18:44.240 --> 0:18:46.880 of like uh for example, like let's say I get 0:18:46.880 --> 0:18:50.680 a male pasion trying to put on muscle. It's very muscular, 0:18:50.760 --> 0:18:53.200 but they're also trying to like trim down a little bit. 0:18:53.240 --> 0:18:55.520 I'll say to them listening, you can't do both at 0:18:55.560 --> 0:18:58.080 the same time with this medication, because you are going 0:18:58.119 --> 0:19:00.879 to lose muscle no matter how much. Yeah, you can 0:19:00.880 --> 0:19:03.320 continue high protein diet, work out with weights, but you 0:19:03.359 --> 0:19:05.560 are going to lose a significant amount of muscle. Now, 0:19:05.640 --> 0:19:07.439 if you're a person who's either you know, a man 0:19:07.560 --> 0:19:10.120 or woman that doesn't necessarily care about muscles so much 0:19:10.440 --> 0:19:13.000 and you just are looking to lose the weight, this 0:19:13.040 --> 0:19:13.600 is better for. 0:19:13.640 --> 0:19:14.920 That kind of interesting. 0:19:16.160 --> 0:19:17.840 Wait, I want to make sure I'm getting this right. 0:19:18.440 --> 0:19:21.600 So this the weight loss medication makes you lose muscle 0:19:21.680 --> 0:19:22.720 more than it makes you lose. 0:19:22.560 --> 0:19:26.399 Fat, correct, right, Yeah, you lose weight overall. 0:19:27.560 --> 0:19:29.560 That feels like a huge bomb drop to me. I 0:19:29.560 --> 0:19:30.639 did not understand that. 0:19:30.720 --> 0:19:32.840 When you see somebody who's overweight and they want to 0:19:32.880 --> 0:19:35.800 lose weight, and let's say they lost thirty five pounds, 0:19:36.080 --> 0:19:38.000 a large portion of that is going to be muscle 0:19:38.040 --> 0:19:41.199