WEBVTT - Matthew McConaughey Stands Up to Cancer 0:00:00.160 --> 0:00:11.119 Hi Katie, Hi Brian. Well, I'm a little sad today 0:00:11.160 --> 0:00:15.600 because you know, summer is my favorite season, and sadly 0:00:15.720 --> 0:00:18.599 it's drawing to an end, and I'm not ready to 0:00:18.640 --> 0:00:20.560 accept that. So I'm coming out to l A, to 0:00:20.680 --> 0:00:24.040 the land of Sunshine, California. Here I come. Are you 0:00:24.120 --> 0:00:26.800 coming to uh to visit me? Of course I plan 0:00:26.880 --> 0:00:29.440 to see while I'm in town, but also Ellie, my 0:00:29.560 --> 0:00:33.000 daughter who lives in Los Angeles. But the real reason 0:00:33.080 --> 0:00:35.839 I'm coming, as much as I love you and Ellie 0:00:35.920 --> 0:00:39.720 my daughter, is to support a cause that's very near 0:00:39.800 --> 0:00:41.680 and dear to my heart and one that I really 0:00:41.680 --> 0:00:46.320 haven't talked about that much on this podcast until today. 0:00:46.360 --> 0:00:49.880 That is That's right in this episode, ladies and gentlemen, 0:00:49.960 --> 0:00:52.320 I hope you're going to be excited about this because 0:00:52.440 --> 0:00:55.960 it's something that I'm so passionate about. We'll be diving 0:00:56.000 --> 0:01:00.000 into cancer and cancer research. Many of you might remember 0:01:00.080 --> 0:01:04.720 or that I lost my extraordinary first husband, Jay Monahan, 0:01:05.120 --> 0:01:08.440 to colon cancer twenty years ago, if you can believe that, 0:01:08.720 --> 0:01:12.120 right before his forty second birthday. I was the co 0:01:12.240 --> 0:01:16.039 anchor of the Today Show and many viewers lived the 0:01:16.080 --> 0:01:19.559 experience almost along with me. And just a few years later, 0:01:19.600 --> 0:01:23.560 I lost my sister Emily two pancreatic cancer when she 0:01:23.680 --> 0:01:28.240 was fifty four in a rising star and politics uh 0:01:28.480 --> 0:01:33.360 to tremendous losses for me and my family and Jay's family. 0:01:33.840 --> 0:01:36.319 But what people might not realize, Katie, is that you 0:01:36.400 --> 0:01:40.520 actually turned those tragedies into something more positive because you 0:01:40.600 --> 0:01:44.880 co founded with eight other women this extraordinary organization called 0:01:45.120 --> 0:01:47.440 Stand Up to Cancer. And I was blown away to 0:01:47.520 --> 0:01:51.320 learn that you've raised nearly half a billion dollars since 0:01:51.360 --> 0:01:54.200 it was founded ten years ago. You know, I couldn't 0:01:54.520 --> 0:01:57.280 just rest on my laurels when it came to colin 0:01:57.320 --> 0:02:01.000 oscophees Brian. I felt that so many cans sers deserved 0:02:01.040 --> 0:02:05.040 our attention, and the ladies at Stand Up to Cancer 0:02:05.120 --> 0:02:08.160 and the entire organization, because after all, it does take 0:02:08.200 --> 0:02:12.080 a village, will not rest until more money is raised. 0:02:12.200 --> 0:02:14.920 And the day after this episode drops, I'll be in 0:02:15.080 --> 0:02:18.160 l A to mark the ten year anniversary of Stand 0:02:18.200 --> 0:02:21.760 Up to Cancer and the live telecast that we've been 0:02:21.800 --> 0:02:25.880 having every other year since its inceptions, So if you'd 0:02:25.919 --> 0:02:29.960 like to tune in, the telecast will be broadcast on 0:02:30.120 --> 0:02:34.400 seventy broadcast and cable networks as well as streaming platforms 0:02:34.480 --> 0:02:38.160 and online So honestly, if you're anywhere near a screen 0:02:38.240 --> 0:02:40.600 or even a phone, you are not going to be 0:02:40.639 --> 0:02:43.760 able to avoid this telecast on Friday Night, and just 0:02:43.840 --> 0:02:46.560 as an additional sweetener for people. In addition to these 0:02:46.600 --> 0:02:50.200 extraordinary stories an amazing sinus, the telecast is also going 0:02:50.200 --> 0:02:52.679 to feature a lot of star power, including the likes 0:02:52.720 --> 0:02:56.079 of Bradley Cooper and Reese Weatherspoon and ma Hershela Ali. 0:02:56.120 --> 0:02:59.720 I should probably explain, Brian to our listeners how Stand 0:02:59.760 --> 0:03:03.280 Up to Cancer puts the dollars it raises to work. 0:03:03.360 --> 0:03:07.880 Our goal is to really accelerate groundbreaking, promising cancer research 0:03:08.240 --> 0:03:13.639 and mandate we don't encourage, we require collaboration instead of competition. 0:03:13.800 --> 0:03:17.200 So we have set up dream teams of scientists who 0:03:17.200 --> 0:03:22.480 are focused on various cancers like pancreatic cancer or nanotechnology. 0:03:22.600 --> 0:03:26.840 Epigenetics have become quite the scientific researcher, right, Brian, and 0:03:26.880 --> 0:03:30.720 these dream teams are basically a scientific task force and 0:03:30.880 --> 0:03:34.440 the ideas to get them uh these top researchers from 0:03:34.440 --> 0:03:37.800 different institutions to work together so they can develop new 0:03:37.840 --> 0:03:42.960 approaches and new treatments for this terrible disease that claims 0:03:43.040 --> 0:03:46.600 far too many lives every single year. And later in 0:03:46.600 --> 0:03:49.040 the show, we're going to hear from a top oncologist 0:03:49.120 --> 0:03:52.880 who has contributed enormously to Stand Up to Cancers research efforts. 0:03:52.920 --> 0:03:55.600 He answers a lot of your questions and mind Katie 0:03:55.680 --> 0:04:00.440 about the future of cancer research, the most promising therapies, now, 0:04:00.680 --> 0:04:03.920 what you should do if you're diagnosed with cancer, etcetera, etcetera, 0:04:04.200 --> 0:04:07.280 And he will give us the big picture. Bill Nelson, 0:04:07.480 --> 0:04:09.520 I have a little crush on Bill. Don't tell him, 0:04:09.520 --> 0:04:12.120 by the way, Brian. But another person I have a 0:04:12.120 --> 0:04:15.040 little crush on is Matthew McConaughey. He's been such an 0:04:15.040 --> 0:04:18.599 important supporter of Stand Up to Cancer and we're so 0:04:18.680 --> 0:04:22.920 lucky to have so many celebrities stand with us. And 0:04:22.960 --> 0:04:26.359 that's because, what can I say, Brian, stars, they're just 0:04:26.560 --> 0:04:30.000 like us, they too have been affected by cancer. So 0:04:30.080 --> 0:04:33.520 I recently chatted with Matthew about why this work has 0:04:33.640 --> 0:04:37.919 become so important to him and how it's affected him personally. 0:04:42.200 --> 0:04:44.480 Tell me why you wanted to get involved with Stand 0:04:44.520 --> 0:04:48.240 Up to Cancer? Um, I think I was involved in 0:04:48.279 --> 0:04:51.800 Stand Up to Cancer actually before cancer affected people very 0:04:51.800 --> 0:04:54.680 close to me. So Lisa Boston asked me to be 0:04:54.760 --> 0:04:59.120 involved in two thousand fifteen with the whole campaign, and 0:04:59.160 --> 0:05:02.280 I said yes. And then shortly after that, I believe 0:05:02.400 --> 0:05:05.120 is when it actually cancer did affect some people in 0:05:05.800 --> 0:05:09.360 my near circumference, very very good friend of mine, one 0:05:09.400 --> 0:05:12.720 of my best friends of twenty years um got cancer, 0:05:12.760 --> 0:05:15.919 and then um someone in my family got it. And 0:05:16.080 --> 0:05:20.200 you know when it happened. Uh want it scary too? 0:05:21.040 --> 0:05:22.839 You want to go, well, I need. I want to 0:05:22.839 --> 0:05:26.440 get all the information I can. You know what experts 0:05:27.040 --> 0:05:32.880 can help me, can help. Then It's amazing how when 0:05:32.880 --> 0:05:37.120 a cancer diagnosis affects someone you know and love, or 0:05:37.160 --> 0:05:42.120 even yourself, it's you're suddenly immersed in this new world 0:05:42.600 --> 0:05:51.240 of terms and sort of science and drugs and alternative 0:05:51.320 --> 0:05:56.880 therapies and approaches. It can be so overwhelming, can it? Yes? 0:05:57.320 --> 0:05:59.599 And I think it's hard, especially if you're going through 0:05:59.640 --> 0:06:02.839 it you're self sometimes. I know, in the case of 0:06:02.880 --> 0:06:06.160 my husband, when he was diagnosed, as smart as he was, 0:06:06.800 --> 0:06:10.000 he didn't really want to know. He didn't want to 0:06:10.040 --> 0:06:14.320 see the research for the science and his statistics. He didn't, 0:06:14.480 --> 0:06:18.560 so you did, and then you helped shepherd and guide 0:06:18.600 --> 0:06:21.839 him from there. Okay, yes, And I think that's the case. 0:06:22.360 --> 0:06:26.279 I think some patients want to know and some patients don't. 0:06:26.480 --> 0:06:30.440 And did you feel like you needed to be that 0:06:31.560 --> 0:06:35.719 sort of explorer and you needed to really understand it 0:06:35.880 --> 0:06:38.520 so you could help the people you love? That That's 0:06:38.520 --> 0:06:40.640 exactly I felt like I was the one who needed 0:06:40.640 --> 0:06:43.800 to do the expiration. I was the one who needs 0:06:43.839 --> 0:06:46.360 to get the access to the expert, get the knowledge, 0:06:46.480 --> 0:06:50.080 gather it as much and fore and wide as I could, 0:06:50.880 --> 0:06:54.840 and then sit down and go over options, and go 0:06:54.920 --> 0:07:00.000 over practicalities, and go over long shots and go over repercussion. 0:07:00.000 --> 0:07:02.320 And you do this. This is you know, it goes 0:07:02.360 --> 0:07:04.560 to that question this makes in life? But there may 0:07:04.600 --> 0:07:07.719 be more pain than you have that question quality of 0:07:07.760 --> 0:07:12.880 life versus quantity Along the way and um, different questions arise, 0:07:13.400 --> 0:07:15.520 And I was I've been in a position where I 0:07:15.560 --> 0:07:18.160 was the hunter and gatherer of the information and went 0:07:18.200 --> 0:07:20.000 to stand up to cancer to find out so much 0:07:20.000 --> 0:07:22.840 of that information. And then, as you know, it's up 0:07:22.880 --> 0:07:26.640 to the individual has it. It's there there. It becomes 0:07:26.640 --> 0:07:30.120 down to that personal choice, which is, you know, not 0:07:30.240 --> 0:07:33.240 ours unless we're the unless we're the one to make, 0:07:33.440 --> 0:07:35.640 which is, what do you want to do, and there's 0:07:35.680 --> 0:07:39.240 many there's many signposts along the way. Here's where we are, 0:07:40.160 --> 0:07:43.320 here's the new here's a new evolution in the disease. 0:07:43.480 --> 0:07:45.120 What do you want to do, Here's what we can do, 0:07:45.280 --> 0:07:49.480 what would you like to do? In some cases, there's 0:07:49.520 --> 0:07:53.320 not a lot that can be done, and it's very 0:07:53.360 --> 0:07:58.200 difficult in this day and age when there's so many 0:07:58.640 --> 0:08:01.760 you know, medications and science has taken us so far 0:08:01.960 --> 0:08:06.080 that many of these cancers continue to be so vaccine. Yeah, 0:08:06.240 --> 0:08:10.680 I mean, look, there's obviously there's not a magic pill. Um, 0:08:10.760 --> 0:08:14.320 there's not that major break that says we've figured it out, 0:08:14.400 --> 0:08:18.600 we know how to cure all these many types of cancer. Um. 0:08:18.640 --> 0:08:24.640 And so that's frustrating, um, but it's a reality. And 0:08:24.680 --> 0:08:26.320 as you know, you gotta get on with the reality 0:08:26.400 --> 0:08:30.120 that we if we the people's shepherding and helping out 0:08:30.120 --> 0:08:33.240 those with cancer, if we get over the frustrated, it's 0:08:33.280 --> 0:08:36.160 no help to the to the to the to the 0:08:36.240 --> 0:08:40.640 victim or the one with cancer. So I just I 0:08:40.720 --> 0:08:43.400 just personally try to take a very practical approach and say, 0:08:43.760 --> 0:08:45.880 let me keep pounding on trying to do the homework. 0:08:46.320 --> 0:08:50.640 Let me personally talk to that their doctor along the 0:08:50.720 --> 0:08:53.360 way and get let me can give me the straight 0:08:53.440 --> 0:08:55.800 nuts emotionally along the way. What what are we really 0:08:55.800 --> 0:08:59.800 talking about? What's the you know what? Give me percentages? 0:09:00.000 --> 0:09:01.839 Where are we? And let's be real. And both of 0:09:01.880 --> 0:09:04.080 both the people that my friend and the family member 0:09:04.080 --> 0:09:06.280 that I worked wanted to know the straight stuff. One 0:09:06.320 --> 0:09:09.120 of them towards the end didn't want to know it anymore. 0:09:09.160 --> 0:09:11.320 So not I don't want to hear anymore. Just let 0:09:11.400 --> 0:09:15.320 me enjoy in my ignorance right now. I don't want 0:09:15.360 --> 0:09:18.520 to hear anymore the stats for me. The other one 0:09:18.600 --> 0:09:21.480 wanted to know the whole way, the whole way until 0:09:21.600 --> 0:09:25.920 until they actually ended up they did move on. I 0:09:26.000 --> 0:09:28.280 was gonna ask you about the outcome for both of 0:09:28.280 --> 0:09:31.079 these people. We'll both have moved on. They're no longer 0:09:31.360 --> 0:09:35.040 with us in this life on this earth. Um. Besides, 0:09:35.920 --> 0:09:38.760 as you know, with just the disease of cancer, there's 0:09:38.760 --> 0:09:43.720 a lot of personal want to needs that anyone on 0:09:43.760 --> 0:09:48.640 the way out once or doesn't want, um do they 0:09:48.840 --> 0:09:50.599 it was there are things incomplete in their life for 0:09:50.640 --> 0:09:53.240 their relationships that were incomplete that they just want to have. 0:09:53.600 --> 0:09:55.600 Let me just finish that off. Then there's the question 0:09:55.640 --> 0:09:59.079 of you know, how much pain do you want to 0:09:59.120 --> 0:10:02.800 go through? Is more time I'm worth more pain? Or no, 0:10:02.840 --> 0:10:04.240 I want to fight it till the end. I'll go 0:10:04.280 --> 0:10:05.920 through whatever pain because I may be able to break 0:10:05.920 --> 0:10:07.480 through it. How long did you keep fighting on that? 0:10:07.559 --> 0:10:09.520 How long do you go? You know what is too 0:10:09.600 --> 0:10:11.760 much pain? Let me, let let me, let me, let 0:10:11.760 --> 0:10:17.959 me fade out? UM. And then you know you're waiting 0:10:18.000 --> 0:10:20.040 every day and you think something else might come off 0:10:20.040 --> 0:10:21.320 and there is a new break through and the hey, 0:10:21.360 --> 0:10:23.720 we could try this, and then you try all you 0:10:23.760 --> 0:10:26.280 can and so many people have survived, Like I said, 0:10:26.280 --> 0:10:29.679 fifteen and a half million survivors running around living their 0:10:29.720 --> 0:10:35.079 life now UM. And I think less cases now in 0:10:35.080 --> 0:10:37.480 the United States, and it used to be UM. So 0:10:37.600 --> 0:10:40.280 you hope, you know that you're that the person you're 0:10:40.320 --> 0:10:42.120 shepherding is going to be one of those fifteen and 0:10:42.160 --> 0:10:45.720 a half million, or the next, the next one. UM. 0:10:45.760 --> 0:10:49.320 At the same time, I mean this, it's it's the 0:10:49.360 --> 0:10:51.319 son of a bitch man. This thing, it's a beast, 0:10:51.640 --> 0:10:55.760 and we don't have it last so yet. But you know, 0:10:55.880 --> 0:10:58.360 it's like I said at the beginning, and it's helpful 0:10:59.280 --> 0:11:01.600 to whoever as it and it's helpful to ever of 0:11:01.720 --> 0:11:05.080 us is helping do the homework and shepherd our love 0:11:05.120 --> 0:11:07.760 to one out to know that someplace like Stand Up 0:11:07.760 --> 0:11:09.360 to Cancer is a place. It's going to get you 0:11:09.400 --> 0:11:11.680 all the information you can get, so you don't have 0:11:11.720 --> 0:11:14.120 a black hole there once in case they do move on. 0:11:14.240 --> 0:11:16.760 Oh should I? Would I? And could I have? That's 0:11:16.760 --> 0:11:19.080 the way I felt with my husband. You know, I 0:11:19.120 --> 0:11:22.000 wanted to make sure I did everything I possibly could. 0:11:22.679 --> 0:11:25.720 So this was before Stand Up to Cancer even existed, 0:11:26.280 --> 0:11:30.360 but I was calling pharmaceutical companies in Israel. I was 0:11:30.440 --> 0:11:37.120 doing so much research and calling universities and organizations and 0:11:37.240 --> 0:11:41.839 hoping that we could manage his disease long enough that 0:11:42.000 --> 0:11:46.160 another thing, another breakthrough would occur. And I think that's 0:11:46.679 --> 0:11:49.320 how you operate when you're trying to help someone you 0:11:49.400 --> 0:11:52.360 love with you were operating like that. At the same 0:11:52.400 --> 0:11:55.160 time this, Your husband was like, I don't want to 0:11:55.559 --> 0:11:58.120 I don't want to know anymore. Don't tell me about it, kay, 0:11:58.160 --> 0:11:59.880 Do you do the do the homework for me? Let me? 0:12:00.360 --> 0:12:02.000 Was he saying, just tell me where to go, but 0:12:02.040 --> 0:12:03.679 I don't want to know all of them? He didn't 0:12:03.679 --> 0:12:09.360 really say it specifically, But I also shielded him from 0:12:09.440 --> 0:12:13.720 a lot, which now I have some regrets about because 0:12:14.000 --> 0:12:16.000 I think I didn't want to tell him how bad 0:12:16.040 --> 0:12:20.280 it was, because he was so advanced when he was diagnosed. 0:12:20.480 --> 0:12:22.400 You know, he had stage four calling cancer and he 0:12:22.440 --> 0:12:25.880 had tumors all over his liver and it was just 0:12:25.960 --> 0:12:31.360 so bleak that I made the choice of feeling that 0:12:32.040 --> 0:12:34.840 I didn't want to ruin whatever time he had left. 0:12:35.679 --> 0:12:38.080 But that really wasn't my decision to make, so now 0:12:38.120 --> 0:12:41.480 I feel bad about it. Maybe it was, I don't know. 0:12:42.200 --> 0:12:45.079 I know when you played ron Woodriff and Dallas Buyer's Club, 0:12:46.080 --> 0:12:49.160 the HIV positive person who told I was told you 0:12:49.160 --> 0:12:54.160 at thirty days, which was such an unbelievable, extraordinary performance. 0:12:54.200 --> 0:12:57.080 I know you won an Academy Award for that, but 0:12:57.160 --> 0:13:00.559 you actually channeled a little bit of int of yours 0:13:00.640 --> 0:13:05.600 who you saw dying of cancer. Oh yeah, yeah, yes, yeah, 0:13:05.640 --> 0:13:09.600 that would be a third that was that was pre 0:13:09.840 --> 0:13:14.199 two thousand and fifteen. Yes, indeed, it was a good 0:13:14.200 --> 0:13:17.199 friend of mine who slowly can't got the best of him. 0:13:17.640 --> 0:13:21.400 Um and he was one of those fighters. He was 0:13:21.480 --> 0:13:26.520 one of those you know, uh till the bitter in teeth, 0:13:26.640 --> 0:13:31.120 non growling streaming como gritting to youth, I'm going to 0:13:31.240 --> 0:13:35.840 make it, which is what he he gnawed at the situation, 0:13:36.120 --> 0:13:38.719 did not want to go gently into this good night 0:13:39.040 --> 0:13:43.040 going to fade out at all, um, And he didn't 0:13:43.760 --> 0:13:48.560 until his his body broke down enough where his willpower 0:13:48.600 --> 0:13:51.320 couldn't overcome it. But you used him in a way, 0:13:51.559 --> 0:13:57.240 the image of him to model a little bit from performance. 0:13:58.320 --> 0:14:00.600 I don't know how literal that would that was. It 0:14:00.720 --> 0:14:03.920 was just somebody, uh in my life and a friend 0:14:03.960 --> 0:14:05.880 who had come and he had always been a fighter 0:14:06.040 --> 0:14:09.120 when before he was sick, and then afterwards I just 0:14:09.160 --> 0:14:12.560 remember there's that he was. You know, he was like 0:14:12.559 --> 0:14:16.000 a like a coyote and he just like if if 0:14:16.040 --> 0:14:17.800 he was stuck, he was willing to no off his 0:14:17.880 --> 0:14:19.400 leg to get out of the trap. He was willing 0:14:19.440 --> 0:14:23.960 to do to do anything. And so he went pretty quickly, 0:14:24.200 --> 0:14:27.080 you know, like he I saw him very shortly before 0:14:27.120 --> 0:14:29.360 he moved on, and he still had as much fighting 0:14:29.440 --> 0:14:34.640 him as he did you know, eight months earlier. Um, 0:14:34.680 --> 0:14:39.440 But it was it was more his willpower to say no, no, no, 0:14:39.920 --> 0:14:41.800 I'm not going, and if I do go, it's going 0:14:41.840 --> 0:14:44.720 to be on the last drop of of life that 0:14:44.760 --> 0:14:47.800 I have. Is there something about stand Up to Cancer 0:14:47.880 --> 0:14:52.560 and the way it's sort of operating and focusing on 0:14:52.640 --> 0:14:59.040 collaboration versus competition and really trying to change how cancer 0:14:59.080 --> 0:15:02.760 research is on that made you want to support this 0:15:02.880 --> 0:15:05.520 organization because there are a lot of groups doing great 0:15:05.600 --> 0:15:10.200 work when it comes to cancer. I mean, look all 0:15:10.280 --> 0:15:15.640 medicine and medicine should not, nor has ever invented to 0:15:15.680 --> 0:15:19.480 become a competition. And we know rightfully so that it's 0:15:19.520 --> 0:15:22.760 also a big business, which makes it a competition in places. 0:15:23.280 --> 0:15:28.720 Um Uh, you know it's it's like it's like teaching, 0:15:29.200 --> 0:15:30.440 you know what I mean. It's like if you have 0:15:30.520 --> 0:15:34.560 a if you have a good idea, a good class, 0:15:34.600 --> 0:15:38.000 scale it out, share it for free. Come on, what's 0:15:38.000 --> 0:15:41.640 the end goal? Um? So the collaboration that Stand Up 0:15:41.760 --> 0:15:45.760 uses is how it ought to be. Um, I wouldn't be. 0:15:45.880 --> 0:15:48.080 You know, there are some people that, yes, compete, they 0:15:48.080 --> 0:15:50.080 still do some good work, but it shouldn't be a 0:15:50.160 --> 0:15:54.600 private club. You know that that somebody who's not in 0:15:54.680 --> 0:15:57.920 that club does not have access to the expertise that 0:15:57.920 --> 0:16:00.720 they could offer. So, you know, and we don't have it. 0:16:00.720 --> 0:16:02.480 It's not figured out yet, So we need a lot 0:16:02.520 --> 0:16:04.840 more collaboration. No one's got that, Like I said, no 0:16:04.840 --> 0:16:07.440 one's got the magic pill, you know, So let's go 0:16:07.560 --> 0:16:11.320 far and wide because all you know, all bets are 0:16:11.320 --> 0:16:13.120 still on the table for what's the best way and 0:16:13.160 --> 0:16:16.120 how to handle and diagnose and treat different type of 0:16:16.160 --> 0:16:20.240 cancers are For so long, research was siloed and people 0:16:20.280 --> 0:16:27.720 did not share their knowledge or test results or tissue samples. 0:16:27.840 --> 0:16:33.000 And the thought is, if we do collaborateive scientists share 0:16:33.480 --> 0:16:37.280 what they're doing, then if two heads are better than one, 0:16:37.360 --> 0:16:40.240 ten heads are better than two, and we can get 0:16:40.280 --> 0:16:43.640 treatments to patients in a much faster at a much 0:16:43.680 --> 0:16:48.080 faster rate. That's just common sense, you know. I know 0:16:48.200 --> 0:16:51.480 that your most famous line from your very first movie, 0:16:51.560 --> 0:16:56.600 which I rewatched days and dazed and confused. This morning 0:16:56.640 --> 0:16:58.800 we watched some clips. It's a good way to start today. 0:16:59.040 --> 0:17:02.760 You just got to keep living, man. Is that is 0:17:02.800 --> 0:17:08.439 that your message to people who are fighting cancer? Too? Sure? 0:17:08.600 --> 0:17:11.600 I mean, that's that's a line that that is universal. 0:17:11.640 --> 0:17:13.800 You had a specific to everybody. They can imply to 0:17:13.840 --> 0:17:16.280 their own lives however they want to um. It was 0:17:16.320 --> 0:17:19.560 inspired because my father moved on and it was about 0:17:19.600 --> 0:17:21.120 how I was how I was dealing with my relationship 0:17:21.119 --> 0:17:22.720 with him, and he had just moved on. So that 0:17:22.840 --> 0:17:25.600 was five days into your shooting. That five days into 0:17:25.600 --> 0:17:28.879 shooting Day's Confuse was my first acting job. My father 0:17:28.920 --> 0:17:32.480 moved on and uh I went home for that weekend, 0:17:32.560 --> 0:17:34.200 spent the weekend. We had to wake and the whole 0:17:34.200 --> 0:17:37.520 family should get you back there to work. Um, nothing 0:17:37.520 --> 0:17:38.960 you can do here, go back to it. And I 0:17:38.960 --> 0:17:41.080 think it was like the first night we were back. 0:17:41.119 --> 0:17:42.800 It was seen on the football field and I had 0:17:42.800 --> 0:17:46.640 been obviously, you know, doing some soul searching with how 0:17:46.680 --> 0:17:50.400 to what it all meant. Physically was gone, but they 0:17:50.440 --> 0:17:53.520 just keep living. Came from well you still keep someone 0:17:53.560 --> 0:17:56.920 spirit alive even though maybe physically they're not here, not personally, 0:17:57.400 --> 0:18:01.080 you know. For me, just keep living. I applied to 0:18:01.119 --> 0:18:02.719 many parts of my life, and I think everyone can 0:18:02.760 --> 0:18:05.040 apply it in their own different way. It's just keep living. Mean, 0:18:05.600 --> 0:18:07.880 I want to like that friend of mine that's going, 0:18:07.880 --> 0:18:09.199 I want to live as long I want to live. 0:18:09.240 --> 0:18:11.479 I'll take quantity over quality. I don't care how much 0:18:11.520 --> 0:18:13.600 pain them in. I want to live longer. For some 0:18:13.720 --> 0:18:16.520 it is others that just keep living choice Maybe you 0:18:16.560 --> 0:18:21.760 know what enough of the pain right now. I'm I'm 0:18:21.800 --> 0:18:24.560 I'm I'm ready. I'm talking about quality of life. And 0:18:24.560 --> 0:18:28.600 I don't want to take the pain that I'm in 0:18:28.680 --> 0:18:32.399 right now for another however, many weeks, days, months. I 0:18:32.440 --> 0:18:34.600 don't want the quantity. I don't want more quantity. I'm 0:18:34.640 --> 0:18:39.560 good right now, And that's up to each individual to say. 0:18:39.760 --> 0:18:43.240 And it's also, as you know, it's it's a conversation 0:18:44.720 --> 0:18:46.600 that we need to have with our friends and loved 0:18:46.600 --> 0:18:51.359 ones before they're so sick, before they're in that much pain, 0:18:51.680 --> 0:18:54.639 to have it, you know, and at a time where 0:18:55.200 --> 0:18:58.560 there is lucid as possible as a society, we have 0:18:58.880 --> 0:19:04.280 such hard time talking about death. Yeah, and yet it's 0:19:04.320 --> 0:19:06.239 one of the things, one of the guarantees, you know. 0:19:06.440 --> 0:19:08.600 I wish we didn't have such a hard time talking 0:19:08.600 --> 0:19:11.320 about it. I think sometimes talking about it it feels 0:19:11.320 --> 0:19:14.800 like a concession to some people, you know, I've got 0:19:14.880 --> 0:19:17.399 to I've got a woman very close to me who 0:19:17.600 --> 0:19:22.680 who um beat three types of cancer and didn't tell 0:19:23.080 --> 0:19:24.960 didn't tell me she had it until her third one 0:19:25.160 --> 0:19:26.680 and never went to doctors, And what were you doing 0:19:26.680 --> 0:19:30.560 for what she was taking to aspirin? But her attitude 0:19:30.920 --> 0:19:34.000 and her mental makeup had so much to do where 0:19:34.000 --> 0:19:37.000 they're making it. Um, she was actually stayed in denial. 0:19:37.480 --> 0:19:40.200 So I think talking about death or even sometimes people 0:19:40.240 --> 0:19:43.000 going to see a doctor to concede and go I 0:19:43.080 --> 0:19:46.440 need to get some help can make sometimes make our 0:19:46.520 --> 0:19:50.480 our our our immune and innate reaction be like, oh 0:19:50.560 --> 0:19:53.920 now I've now I'm a victim. Now I'm now I'm 0:19:53.960 --> 0:19:56.440 conceding that death is out there, and I think something 0:19:56.480 --> 0:19:59.640 that feels on people feel weak about that. But um, 0:19:59.680 --> 0:20:01.320 I think it's good if we can talk about it 0:20:01.440 --> 0:20:05.480 up front as early as possible, because it's happening one 0:20:05.520 --> 0:20:09.000 day or another. It's happening. Well, as somebody involved with 0:20:09.040 --> 0:20:10.880 Stand Up to cancer, I can't tell you how much 0:20:10.920 --> 0:20:16.520 we appreciate your lending your name and celebrity to this 0:20:16.720 --> 0:20:20.959 because I think it inspires other people and makes them 0:20:21.040 --> 0:20:23.840 want to get involved. And if they see someone they 0:20:23.880 --> 0:20:27.320 admire and like kind of standing up for stand up, 0:20:27.920 --> 0:20:31.159 hopefully they'll follow suits. So thank you for doing that. Well, 0:20:31.200 --> 0:20:34.119 I've got a personal investment in it people in my 0:20:34.160 --> 0:20:37.000 own life. So who does that? You know? One and 0:20:37.040 --> 0:20:40.040 two men one in three women will be diagnosed in 0:20:40.080 --> 0:20:45.640 their lifetimes, So like it or not. There's very few 0:20:45.640 --> 0:20:50.080 people escape it, so thank you, thank you for doing it. 0:20:50.400 --> 0:20:55.960 My pleasure. That wraps things up with a one and 0:20:56.000 --> 0:20:58.359 only Matthew McConaughey, folks, and we're going to take a 0:20:58.440 --> 0:21:01.320 quick break and we'll be back with our second guest, 0:21:01.800 --> 0:21:06.040 Dr Bill Nelson, from the Sydney Kimmel Comprehensive Cancer Center 0:21:06.440 --> 0:21:15.119 at Johns Hopkins University in Baltimore. We're back, you know, Brian. 0:21:15.160 --> 0:21:18.400 As much as I appreciate celebrities like Matthew McConaughey who 0:21:18.480 --> 0:21:21.480 lend their star support to this cause, some of the 0:21:21.560 --> 0:21:24.159 real heroes in this fight, I'm sure Matthew would agree, 0:21:24.400 --> 0:21:28.040 are the scientists and doctors and clinicians who are working 0:21:28.160 --> 0:21:30.600 day in and day out to find new ways to 0:21:30.640 --> 0:21:36.840 help patients fighting cancer. I disagree. No'm for our second 0:21:36.880 --> 0:21:39.240 and final chapter today, we're going to talk with one 0:21:39.280 --> 0:21:41.760 of these heroes, Dr Bill Nelson. As you mentioned, he's 0:21:41.840 --> 0:21:45.879 nationally recognized as a physician and scientist, and he specializes 0:21:45.960 --> 0:21:49.880 in treating and researching prostate cancer. In fact, he discovered 0:21:49.920 --> 0:21:53.840 the most common genome alteration in prostate cancer, which has 0:21:53.880 --> 0:21:57.440 led to more diagnostic tests for the disease. Talk about impressive. 0:21:57.680 --> 0:22:00.800 He's the director of the Sydney Kimmel Brands of Cancer 0:22:00.840 --> 0:22:03.679 Center at Johns Hopkins and he is also on the 0:22:03.720 --> 0:22:07.359 Stand Up to Cancer Scientific Advisory Committee. So in our 0:22:07.400 --> 0:22:10.240 conversation with Dr Nelson, we dig into his work fighting 0:22:10.280 --> 0:22:13.199 all kinds of cancer and we talked about why the 0:22:13.280 --> 0:22:16.399 approach of Stand Up to Cancer is so unique and 0:22:16.440 --> 0:22:27.880 has already yielded so many promising therapies. Bill, let's talk 0:22:27.920 --> 0:22:30.680 about the model of Stand Up to Cancer and from 0:22:30.720 --> 0:22:35.040 a scientist perspective, how is it different and why in 0:22:35.080 --> 0:22:38.000 your view is it a positive thing? Well, I think 0:22:38.040 --> 0:22:41.359 that the thing that attracted so much of the scientific 0:22:41.440 --> 0:22:46.439 and cancer research community initially was its ambition. These women 0:22:46.480 --> 0:22:48.760 had gotten together, as you know, and they wanted to 0:22:48.800 --> 0:22:51.080 do something bold, and they wanted to do something big. 0:22:51.480 --> 0:22:54.440 And their thought was that if everyone could come together 0:22:54.840 --> 0:22:57.879 in dream teams we called them, in which case you 0:22:57.920 --> 0:23:01.480 had everybody who could help on a particular cancer problem, 0:23:01.520 --> 0:23:04.919 they could focus on this problem, get considerable investment of 0:23:04.960 --> 0:23:07.520 resources over a short period of time, that they could 0:23:07.560 --> 0:23:11.720 make a huge difference quickly, Dr Nelson, Bill, if I 0:23:11.840 --> 0:23:16.360 might before stand Up to Cancer, what did the world 0:23:16.359 --> 0:23:20.000 of cancer research look like, why was there this need 0:23:20.160 --> 0:23:24.680 to create dream teams and collaborate. Well, you had very 0:23:24.760 --> 0:23:28.240 dedicated people trying to make an impact on the cancer field. 0:23:28.600 --> 0:23:30.840 They were very competitive, and some of that was good 0:23:30.920 --> 0:23:35.720 in trying to outsmart or be cleverer than cancer than 0:23:35.840 --> 0:23:38.560