1 00:00:00,800 --> 00:00:04,040 Speaker 1: Perry. Have you ever been pregnant? 2 00:00:04,960 --> 00:00:07,520 Speaker 2: No, not to my knowledge, but my wife has been 3 00:00:07,560 --> 00:00:08,840 Speaker 2: pregnant several times. 4 00:00:09,480 --> 00:00:14,280 Speaker 3: Did you know that when you are pregnant, fetal cells 5 00:00:14,480 --> 00:00:17,560 Speaker 3: get into your bloodstream and they live there forever, So 6 00:00:17,720 --> 00:00:22,680 Speaker 3: your children's cells are still circulating around your wife's brain 7 00:00:22,960 --> 00:00:23,640 Speaker 3: as we speak. 8 00:00:24,360 --> 00:00:29,080 Speaker 2: That is crazy. I mean I believe it pregnancy as 9 00:00:29,120 --> 00:00:32,040 Speaker 2: I went back to my med school notes for this 10 00:00:32,120 --> 00:00:38,600 Speaker 2: episode to like remind myself about how incredibly bonkers the 11 00:00:38,640 --> 00:00:43,519 Speaker 2: physiology is in pregnancy. I mean it is literally like 12 00:00:43,600 --> 00:00:46,640 Speaker 2: if I didn't know that it served some evolutionary purpose, 13 00:00:47,040 --> 00:00:50,159 Speaker 2: I would be like, well, this is clearly a terminal disease, 14 00:00:50,280 --> 00:00:51,320 Speaker 2: like no one can survive this. 15 00:00:53,240 --> 00:00:54,000 Speaker 1: I totally agree. 16 00:00:54,000 --> 00:00:55,680 Speaker 3: And that is in fact, how it feels some of 17 00:00:55,720 --> 00:00:57,920 Speaker 3: the time while you are pregnant, I will tell you. 18 00:00:58,240 --> 00:01:03,720 Speaker 3: And today we're to talk about pregnancy brain and the 19 00:01:03,720 --> 00:01:08,360 Speaker 3: ways that pregnancy makes your brain worse or maybe better, 20 00:01:08,640 --> 00:01:10,639 Speaker 3: or maybe different and both. 21 00:01:11,080 --> 00:01:15,319 Speaker 1: And we've brought in a special guest, special scientist. 22 00:01:16,000 --> 00:01:21,440 Speaker 3: We've run a special neuroscientist adjacent guest. Now, Allison would 23 00:01:21,600 --> 00:01:24,679 Speaker 3: like to introduce yourself and tell us why you're here. 24 00:01:25,000 --> 00:01:29,160 Speaker 4: I am here by force, I like basically commissioned this 25 00:01:29,240 --> 00:01:31,560 Speaker 4: episode and forced my way onto the podcast, which I'm 26 00:01:31,600 --> 00:01:34,560 Speaker 4: an obsessive fan of. I want to thank you for 27 00:01:34,640 --> 00:01:38,320 Speaker 4: your work. You've accompanied me through many a It's been 28 00:01:38,400 --> 00:01:40,959 Speaker 4: the equivalent of a panic Google, but much more informed 29 00:01:41,000 --> 00:01:44,039 Speaker 4: and much better. So thank you for saving me from 30 00:01:44,080 --> 00:01:46,399 Speaker 4: panic Googling. Although I guess now we panic Claude I 31 00:01:46,480 --> 00:01:51,040 Speaker 4: ghost mode, panic claud now at dark mode totally anyway, Hi, 32 00:01:51,080 --> 00:01:54,360 Speaker 4: I'm Allison. I am an actress. I'm also a podcaster. 33 00:01:55,080 --> 00:01:59,120 Speaker 4: I basically have been wondering for years now whether my 34 00:02:00,160 --> 00:02:04,360 Speaker 4: brain actually physically changed in a permanent way such that 35 00:02:04,440 --> 00:02:09,600 Speaker 4: I now have a different amount of or new presentation 36 00:02:09,880 --> 00:02:14,560 Speaker 4: of ADHD in adulthood, or if I always had it 37 00:02:14,600 --> 00:02:16,800 Speaker 4: but my ability to mask it was so good that 38 00:02:16,919 --> 00:02:19,720 Speaker 4: I didn't know, and then once I had a kid 39 00:02:20,280 --> 00:02:22,480 Speaker 4: there's just so much going on that all those coping 40 00:02:22,800 --> 00:02:28,200 Speaker 4: mechanisms no longer worked, Or if I don't have it 41 00:02:28,280 --> 00:02:30,760 Speaker 4: at all, and I just now I am a mom 42 00:02:31,000 --> 00:02:33,800 Speaker 4: and that means that my whole life feels like an 43 00:02:33,840 --> 00:02:37,000 Speaker 4: ADHD diagnosis and looks like one, and thus can be 44 00:02:37,040 --> 00:02:41,080 Speaker 4: treated like one, but isn't actually one. That's kind of 45 00:02:41,120 --> 00:02:43,920 Speaker 4: where this is coming from. And there was a study 46 00:02:43,960 --> 00:02:46,320 Speaker 4: which I'm sure you'll talk about with more. I don't 47 00:02:46,360 --> 00:02:50,400 Speaker 4: know authority and data, but there was a study showing 48 00:02:50,440 --> 00:02:53,960 Speaker 4: that women's brains changed physically during pregnancy and it was 49 00:02:53,960 --> 00:03:01,079 Speaker 4: correlated with postpartum depression. And that fascinated me because I 50 00:03:01,160 --> 00:03:03,800 Speaker 4: also had postpartum depression. And I was like, my brain 51 00:03:03,840 --> 00:03:07,160 Speaker 4: feels super different, but also my life is unrecognizable. And 52 00:03:07,200 --> 00:03:11,239 Speaker 4: so it's one of those what is the causation versus 53 00:03:11,240 --> 00:03:14,520 Speaker 4: correlation questions that I have been asking myself. And then 54 00:03:14,520 --> 00:03:17,160 Speaker 4: I was like, why am I asking myself this? That's useless. 55 00:03:17,200 --> 00:03:21,240 Speaker 4: I know what I know, I think, therefore I am therefore, 56 00:03:21,240 --> 00:03:23,720 Speaker 4: I know nothing extra about this topic, and I need 57 00:03:23,720 --> 00:03:26,239 Speaker 4: to turn to people who actually will And so I 58 00:03:26,320 --> 00:03:30,240 Speaker 4: turned to the best people because I weaponized my status, 59 00:03:30,360 --> 00:03:31,280 Speaker 4: and here I am. 60 00:03:31,720 --> 00:03:33,600 Speaker 1: We are so pleased that you did well. 61 00:03:33,800 --> 00:03:35,760 Speaker 4: Thank you. Now I know there's little bits of my son. 62 00:03:35,840 --> 00:03:37,280 Speaker 4: I can't wait to tell it. He's going to be 63 00:03:37,360 --> 00:03:39,880 Speaker 4: so proud. He's going to be so excited and proud. 64 00:03:43,360 --> 00:03:46,400 Speaker 3: I'm Emily ast I'm an economist and a data expert. 65 00:03:46,520 --> 00:03:47,480 Speaker 2: And I'm Harry Wilson. 66 00:03:47,640 --> 00:03:50,760 Speaker 4: I'm a medical doctor and I'm Alison Williams, actor and 67 00:03:50,840 --> 00:03:53,320 Speaker 4: podcaster and a fan of this very podcast. 68 00:03:53,880 --> 00:03:58,680 Speaker 3: It's Thursday, July sixteenth, twenty twenty six. And this is wellness. 69 00:03:58,040 --> 00:04:01,880 Speaker 2: Actually, because you're getting a staggering amount of health and 70 00:04:01,920 --> 00:04:05,920 Speaker 2: wellness information nowadays from every source imaginable, and some of 71 00:04:05,960 --> 00:04:07,880 Speaker 2: it is awesome and some. 72 00:04:07,760 --> 00:04:10,680 Speaker 1: Of it is well actually both. 73 00:04:11,640 --> 00:04:14,680 Speaker 3: Fortunately, we're both people who know how to read studies, 74 00:04:14,960 --> 00:04:17,240 Speaker 3: how to parse the data, and can tell you what's 75 00:04:17,279 --> 00:04:20,120 Speaker 3: worth thinking about and what you can safely ignore. 76 00:04:20,440 --> 00:04:22,719 Speaker 2: But before we dig in, a note that this podcast 77 00:04:22,800 --> 00:04:25,360 Speaker 2: is for educational purposes and should not be construed as 78 00:04:25,400 --> 00:04:28,600 Speaker 2: medical advice. We don't know your unique situation, so talk 79 00:04:28,640 --> 00:04:30,479 Speaker 2: to your doctor for personal health decisions. 80 00:04:31,120 --> 00:04:34,200 Speaker 3: This week we're asking what's the deal with pregnancy brain? 81 00:04:34,800 --> 00:04:37,839 Speaker 3: Alison Perry and I will give the official smasher pass, 82 00:04:37,839 --> 00:04:39,480 Speaker 3: and then we'll get to your question of the week. 83 00:04:39,520 --> 00:04:41,440 Speaker 1: But first let's do the health news roundup. 84 00:04:41,600 --> 00:04:56,119 Speaker 5: After the break, we're back. 85 00:04:56,800 --> 00:04:59,240 Speaker 3: We've set Alison off to go get her coffee so 86 00:04:59,279 --> 00:05:01,080 Speaker 3: we can cover the health news of the week. 87 00:05:01,480 --> 00:05:01,880 Speaker 1: Harry. 88 00:05:02,000 --> 00:05:06,200 Speaker 3: First up, the last American polio survivor in an iron 89 00:05:06,279 --> 00:05:09,120 Speaker 3: lung dies. I know you know a lot about this, 90 00:05:09,200 --> 00:05:11,320 Speaker 3: I know it has a personal connection. Tell me more. 91 00:05:11,680 --> 00:05:15,800 Speaker 2: Yeah. So, some listeners and certainly many of my friends 92 00:05:15,800 --> 00:05:18,599 Speaker 2: will know that my mom was a polio sufferer. She 93 00:05:18,880 --> 00:05:22,479 Speaker 2: was in an iron lung when she was a little kid. 94 00:05:24,360 --> 00:05:28,520 Speaker 2: She ended up only having paralysis of one lower leg, 95 00:05:29,040 --> 00:05:32,960 Speaker 2: but obviously not everyone was so lucky. Martha and Lillard 96 00:05:33,360 --> 00:05:36,279 Speaker 2: is the last American polio survivor dependent on an iron lung. 97 00:05:36,360 --> 00:05:38,600 Speaker 2: She died at the age of seventy eight on the 98 00:05:38,680 --> 00:05:41,520 Speaker 2: last Friday in June of twenty twenty six. She contracted 99 00:05:41,560 --> 00:05:44,920 Speaker 2: polio a pretty similar year to my mom, nineteen fifty three. 100 00:05:45,040 --> 00:05:48,479 Speaker 2: That was her fifth birthday. That was two years before 101 00:05:49,040 --> 00:05:53,440 Speaker 2: the vaccine became widely available in the US. People don't 102 00:05:53,480 --> 00:05:56,760 Speaker 2: realize this now, obviously, but that was the reality in 103 00:05:56,839 --> 00:06:00,560 Speaker 2: the pre vaccine era, is that kids could get and 104 00:06:00,720 --> 00:06:04,440 Speaker 2: not all of them, but a fraction of them would 105 00:06:04,440 --> 00:06:11,200 Speaker 2: develop this this paralysis syndrome, which was sometime lifelong. Martha 106 00:06:11,240 --> 00:06:15,120 Speaker 2: Ann was from Shawnee, Oklahoma. She rescued animals, created art 107 00:06:15,160 --> 00:06:18,400 Speaker 2: and poetry, and had recently married her second husband in 108 00:06:18,440 --> 00:06:21,919 Speaker 2: February of twenty twenty six. It's wonderful that she was 109 00:06:21,960 --> 00:06:25,960 Speaker 2: able to lead such a full life. Not all kids 110 00:06:25,960 --> 00:06:29,400 Speaker 2: with polio had that opportunity, and I feel like I 111 00:06:29,480 --> 00:06:34,800 Speaker 2: just need to say that polio only exists in humans. 112 00:06:34,880 --> 00:06:38,760 Speaker 2: It is therefore a candidate for eradication from the earth 113 00:06:39,440 --> 00:06:42,279 Speaker 2: like we did with smallpox. It is on the list, 114 00:06:42,640 --> 00:06:47,120 Speaker 2: but unfortunately, due to recent trends in sort of the 115 00:06:47,200 --> 00:06:52,640 Speaker 2: anti vaccine movement, the eradication program has had some significant 116 00:06:52,640 --> 00:06:56,760 Speaker 2: setbacks and there is polio spreading out there, although not 117 00:06:56,839 --> 00:06:58,080 Speaker 2: in the United States currently. 118 00:06:58,800 --> 00:07:00,920 Speaker 1: Perry did this woman live her whole life in the 119 00:07:00,960 --> 00:07:01,520 Speaker 1: iron lung? 120 00:07:01,760 --> 00:07:06,160 Speaker 2: Is that she apparently for much of her life only 121 00:07:06,240 --> 00:07:09,039 Speaker 2: had to spend the night times in the iron lung, 122 00:07:09,120 --> 00:07:11,200 Speaker 2: so she would sleep there. Although I, as far as 123 00:07:11,200 --> 00:07:13,920 Speaker 2: I understand, she had a couple of bouts of COVID 124 00:07:14,080 --> 00:07:17,400 Speaker 2: and after that point was more or less confined to 125 00:07:17,440 --> 00:07:18,400 Speaker 2: the iron lung. Yeah. 126 00:07:19,400 --> 00:07:22,520 Speaker 3: Amazing, and also, as you say, a reminder that vaccines 127 00:07:22,640 --> 00:07:25,920 Speaker 3: are really, really life saving and important. 128 00:07:26,160 --> 00:07:31,560 Speaker 2: Absolutely, Emily. I was fascinated to see an article that 129 00:07:31,880 --> 00:07:36,680 Speaker 2: writers into Tour de France are using lactate gels. What 130 00:07:36,800 --> 00:07:38,080 Speaker 2: is up with lactate gel? 131 00:07:38,600 --> 00:07:40,440 Speaker 3: Okay, so first of all, I want you guys to 132 00:07:40,520 --> 00:07:42,760 Speaker 3: understand that you're very lucky that I showed up for 133 00:07:42,760 --> 00:07:46,560 Speaker 3: today's recording because we are in the middle of Tour 134 00:07:46,560 --> 00:07:47,360 Speaker 3: de France Stage ten. 135 00:07:47,440 --> 00:07:49,480 Speaker 1: It's an important tour. I could be watching it. 136 00:07:49,400 --> 00:07:52,480 Speaker 3: Live on peacock right now and I'm instead I'm here 137 00:07:52,520 --> 00:07:54,240 Speaker 3: at work. Then I have to watch it later. So 138 00:07:54,640 --> 00:07:55,240 Speaker 3: you're welcome. 139 00:07:55,640 --> 00:07:56,400 Speaker 2: You're the real hero. 140 00:07:56,520 --> 00:07:58,120 Speaker 1: Emily totally okay. 141 00:07:58,280 --> 00:08:02,400 Speaker 3: So there's always every year there's some weird like endurance 142 00:08:02,440 --> 00:08:04,480 Speaker 3: sports science that comes out in the Tour de France, 143 00:08:04,640 --> 00:08:08,360 Speaker 3: because these are like the world's most elite athletes, supported 144 00:08:08,360 --> 00:08:11,920 Speaker 3: by the most amount of money. So like the United 145 00:08:11,960 --> 00:08:16,520 Speaker 3: Arab Emirates is putting just millions and millions of dollars. 146 00:08:16,040 --> 00:08:20,520 Speaker 1: Into getting Tadday Pagatcha to like go a little bit 147 00:08:20,600 --> 00:08:22,000 Speaker 1: faster on his bicycle. 148 00:08:22,400 --> 00:08:22,960 Speaker 5: Yeah. 149 00:08:23,040 --> 00:08:24,320 Speaker 1: Their latest thing is. 150 00:08:25,160 --> 00:08:28,320 Speaker 3: With their gels, which are generally just fructose some combination 151 00:08:28,360 --> 00:08:30,720 Speaker 3: of glucose and fructose which you eat, you know, while 152 00:08:30,720 --> 00:08:32,360 Speaker 3: you are biking very very fast. 153 00:08:32,800 --> 00:08:34,840 Speaker 1: They've added lactate to the gels. 154 00:08:35,080 --> 00:08:35,560 Speaker 2: Interesting. 155 00:08:36,040 --> 00:08:40,720 Speaker 3: The idea is that I think twofold one is you 156 00:08:40,840 --> 00:08:44,480 Speaker 3: can use lactate as a fuel source, and so this 157 00:08:44,600 --> 00:08:48,240 Speaker 3: gives you yet another fuel source to fuel your cycling. 158 00:08:48,960 --> 00:08:52,280 Speaker 3: I think there's also an idea that the lactate can 159 00:08:52,320 --> 00:08:57,719 Speaker 3: make you less tired by eating up the hydrogen ions 160 00:08:57,800 --> 00:09:02,079 Speaker 3: that are produced with lactic acid, So maybe that works. 161 00:09:02,400 --> 00:09:06,920 Speaker 2: I mean, so a little nephrology here. The lactate that's 162 00:09:06,920 --> 00:09:08,839 Speaker 2: going to be in these gels, just a little nephrology 163 00:09:09,240 --> 00:09:12,960 Speaker 2: is almost certainly not lactic acid. It's probably sodium lactate. 164 00:09:13,040 --> 00:09:16,880 Speaker 2: So the conjuget base and lactate, as you say, can 165 00:09:16,960 --> 00:09:20,720 Speaker 2: be used as fuel. That's anaerobic respiration does use lactate, 166 00:09:20,760 --> 00:09:23,560 Speaker 2: and so maybe that's part of it. The other thing 167 00:09:23,600 --> 00:09:27,480 Speaker 2: is that your liver metabolizes lactate into bicarbonate. And I 168 00:09:27,520 --> 00:09:31,040 Speaker 2: know Emily that you're familiar with bicarbonate supplementation during a 169 00:09:31,040 --> 00:09:33,839 Speaker 2: lot of these endurance sports. So I wonder if a 170 00:09:33,840 --> 00:09:36,720 Speaker 2: little bit of this is just like bicarbonate with extra steps. 171 00:09:36,920 --> 00:09:40,640 Speaker 2: But either way, bicarbonate is a good acid scavenger, you know. 172 00:09:41,200 --> 00:09:44,760 Speaker 2: I teach the medical students this like acidosis, Like being 173 00:09:44,800 --> 00:09:49,680 Speaker 2: acidemic sounds so bad, But that being said, one of 174 00:09:49,720 --> 00:09:52,960 Speaker 2: the things that happens when you're acidemic is that hemoglobin 175 00:09:53,880 --> 00:09:57,400 Speaker 2: and you evolve this way, hemoglobin holds onto oxygen less tightly. 176 00:09:57,480 --> 00:10:01,120 Speaker 2: In acidic environments because as you might expect, it's like, oh, 177 00:10:01,160 --> 00:10:04,400 Speaker 2: there's it's getting acidic in here, there's not enough aerobic respiration, 178 00:10:04,520 --> 00:10:07,240 Speaker 2: like have some more oxygen. And so I always worry 179 00:10:07,320 --> 00:10:11,000 Speaker 2: even in the hospital about correcting acidosis too aggressively because 180 00:10:11,040 --> 00:10:13,719 Speaker 2: maybe we don't deliver oxygen as well. So, but I 181 00:10:13,760 --> 00:10:14,679 Speaker 2: don't know, people study it. 182 00:10:14,880 --> 00:10:17,720 Speaker 3: Then what I will say about this is it's probably 183 00:10:17,760 --> 00:10:20,840 Speaker 3: not for you, listener, for two reasons. One, there's actually 184 00:10:20,840 --> 00:10:23,160 Speaker 3: no evidence that this works. I mean, there's only that 185 00:10:23,160 --> 00:10:26,120 Speaker 3: they're using. The only evidence is like from the market. 186 00:10:26,480 --> 00:10:28,280 Speaker 3: You know that the teams are trying to buy all 187 00:10:28,320 --> 00:10:32,160 Speaker 3: these lack day jails. And also they gels cost nine 188 00:10:32,200 --> 00:10:35,400 Speaker 3: dollars each, which is a lot since these guys are 189 00:10:35,440 --> 00:10:38,160 Speaker 3: having like three every hour and that, and there's a 190 00:10:38,160 --> 00:10:40,480 Speaker 3: lot of people on the team, so they're just really 191 00:10:41,000 --> 00:10:42,800 Speaker 3: they're wasting they're spending a lot of money on lack 192 00:10:42,840 --> 00:10:45,120 Speaker 3: day jaels. But it's safer than last year's innovation, which 193 00:10:45,200 --> 00:10:49,360 Speaker 3: was carbon monoxide rebreathing, where you inhaled carbon monoxide to 194 00:10:49,520 --> 00:10:51,960 Speaker 3: raise your which is not that sounds like you don't 195 00:10:52,040 --> 00:10:56,160 Speaker 3: a terrible idea. Don't do that either, Okay, speaking of 196 00:10:56,400 --> 00:11:00,920 Speaker 3: things that are about optimizing. Brian Johnson fame for his 197 00:11:01,120 --> 00:11:04,920 Speaker 3: desire to not die, something we all share, but maybe 198 00:11:04,960 --> 00:11:07,160 Speaker 3: not in the same with the same approach, with the 199 00:11:07,200 --> 00:11:11,520 Speaker 3: same zeal. He has announced that he has been diagnosed 200 00:11:11,520 --> 00:11:16,480 Speaker 3: with something called autoimmune guestritis. He described it as my 201 00:11:16,640 --> 00:11:21,960 Speaker 3: stomach is eating itself. Is that a clinical description, Perry. 202 00:11:22,040 --> 00:11:26,240 Speaker 2: I mean, it's not bad. It's not bad, okay, but 203 00:11:26,400 --> 00:11:30,360 Speaker 2: it's not accurate either. It's evocative though. Automun gustritis is 204 00:11:30,720 --> 00:11:33,160 Speaker 2: as it sounds like an automune condition where your immune system, 205 00:11:33,200 --> 00:11:35,640 Speaker 2: not your own stomach, attacks the acid producing cells in 206 00:11:35,679 --> 00:11:39,040 Speaker 2: your stomach and that has the sort of downstream effect 207 00:11:39,040 --> 00:11:43,080 Speaker 2: of inhibiting iron absorption, and so people can become iron deficient. 208 00:11:43,120 --> 00:11:45,360 Speaker 2: I think that's how they actually picked this up in 209 00:11:45,440 --> 00:11:47,000 Speaker 2: Brian Johnson. For those of you who don't know, I mean, 210 00:11:47,040 --> 00:11:48,440 Speaker 2: I feel like a lot of people know. But Brian 211 00:11:48,480 --> 00:11:52,960 Speaker 2: Johnson is the millionaire guy who like does literally everything 212 00:11:53,280 --> 00:11:56,880 Speaker 2: like he's an end of one experiment on every health 213 00:11:56,960 --> 00:12:01,880 Speaker 2: and wellness thing. From getting his like teenage uns blood transfusions, 214 00:12:02,320 --> 00:12:06,000 Speaker 2: taking methylene blue and wrap a micin and like a 215 00:12:06,040 --> 00:12:08,800 Speaker 2: million other things and then gets a zillion lab tests 216 00:12:08,840 --> 00:12:11,760 Speaker 2: and tries to draw conclusions, which is actually really hard 217 00:12:11,800 --> 00:12:14,000 Speaker 2: because he's doing one hundred and fifty things at once 218 00:12:14,040 --> 00:12:15,120 Speaker 2: to optimize. 219 00:12:14,720 --> 00:12:17,400 Speaker 3: Monitors his erections every night. That's he like has a 220 00:12:17,640 --> 00:12:20,120 Speaker 3: system to see how good his erections are every night? 221 00:12:20,240 --> 00:12:24,559 Speaker 2: Does everyone doesn't do that? That's that's uncommon. That's fine, 222 00:12:24,760 --> 00:12:28,719 Speaker 2: that's fine. So yeah, he's really into the data. And 223 00:12:28,880 --> 00:12:31,240 Speaker 2: and when you know he came out with this automne gastritis, 224 00:12:31,280 --> 00:12:34,040 Speaker 2: it's also a little bit like I should say this, 225 00:12:34,040 --> 00:12:37,280 Speaker 2: this condition can just pop up. Like any autommune condition, 226 00:12:37,400 --> 00:12:39,600 Speaker 2: you don't always know what the precipitate is. But in 227 00:12:39,640 --> 00:12:42,280 Speaker 2: someone who's taking you know, a million different supplements and 228 00:12:42,320 --> 00:12:45,680 Speaker 2: probiotics and methylene blue and rap amcin and all these things, 229 00:12:45,679 --> 00:12:48,280 Speaker 2: it's like, do you think maybe any of these things 230 00:12:48,280 --> 00:12:50,640 Speaker 2: could have had this particular adverse effect? And we'll never 231 00:12:50,679 --> 00:12:52,600 Speaker 2: know because he's doing one hundred and fifty things at once. 232 00:12:53,120 --> 00:12:55,280 Speaker 3: I will tell you the thing about this story I 233 00:12:55,360 --> 00:12:59,079 Speaker 3: found most interesting and would love to understand better, which 234 00:12:59,120 --> 00:13:01,760 Speaker 3: is I think part of how he found this was 235 00:13:02,440 --> 00:13:06,800 Speaker 3: related to his decision to have a colonoscopy. He's actually 236 00:13:06,880 --> 00:13:10,600 Speaker 3: forty eight and this was his first colonoscopy. So this 237 00:13:10,679 --> 00:13:15,200 Speaker 3: is a person who's doing literally everything, it's taking every 238 00:13:15,400 --> 00:13:20,160 Speaker 3: random supplement, but he actually was three years late on 239 00:13:20,160 --> 00:13:24,079 Speaker 3: one of the very basic things that we recommend people 240 00:13:24,200 --> 00:13:26,839 Speaker 3: do to prevent cancer, which is a colonoscopy. 241 00:13:26,920 --> 00:13:29,280 Speaker 1: So there's something so odd in my head about that. 242 00:13:29,360 --> 00:13:32,400 Speaker 3: Like, in the order of things I would say health wise, 243 00:13:32,480 --> 00:13:36,440 Speaker 3: I would put colonoscoby so far above methylene blue, Like 244 00:13:36,480 --> 00:13:39,920 Speaker 3: you couldn't even see methylene blue from the colonoscopy in 245 00:13:39,960 --> 00:13:42,960 Speaker 3: my list, Yeah, do the evidence based things first and 246 00:13:42,960 --> 00:13:45,600 Speaker 3: then you know, play around and then later play play 247 00:13:45,640 --> 00:13:48,520 Speaker 3: around with your stuff. Is we wish him well? 248 00:13:48,559 --> 00:13:50,040 Speaker 2: I guess we do wish him well? 249 00:13:50,200 --> 00:13:51,280 Speaker 1: What is he doing about this? 250 00:13:51,520 --> 00:13:56,680 Speaker 2: Okay, so his team reportedly is talking about doing car 251 00:13:56,800 --> 00:14:01,360 Speaker 2: tee therapy for him. This is this is crazy. So 252 00:14:01,800 --> 00:14:04,160 Speaker 2: there's no actual treatment for an immune gastritis. Like you 253 00:14:04,440 --> 00:14:06,920 Speaker 2: do iron supplementation, you monitor they have an increased risk 254 00:14:06,960 --> 00:14:09,920 Speaker 2: of cancers, and so you just do gaster cancer screening 255 00:14:09,920 --> 00:14:12,000 Speaker 2: when the eddoscopy and stuff. It's just sort of you know, 256 00:14:12,160 --> 00:14:16,400 Speaker 2: supportive care. Car T cell therapy is like primarily a 257 00:14:16,600 --> 00:14:19,160 Speaker 2: therapy for cancer where you take people's T cells out 258 00:14:19,160 --> 00:14:21,960 Speaker 2: of their body and you rev them up so they're hyperactive, 259 00:14:22,400 --> 00:14:25,120 Speaker 2: and you infuse them back in and you have this 260 00:14:25,360 --> 00:14:29,040 Speaker 2: massive immune reaction that's supposed to kill tumor cells. In 261 00:14:29,080 --> 00:14:32,520 Speaker 2: the hospital, the reaction that patients get when you reinfuse 262 00:14:32,720 --> 00:14:36,120 Speaker 2: car T cells into them, that inflammatory immune reaction is 263 00:14:36,200 --> 00:14:41,440 Speaker 2: so robust we call it a cartastrophe. They often get 264 00:14:41,480 --> 00:14:44,400 Speaker 2: into the intensive care unit with an it looks like 265 00:14:44,440 --> 00:14:47,080 Speaker 2: septic shock, like their pressure is bottoming out and their 266 00:14:47,120 --> 00:14:49,880 Speaker 2: you know, their fever is spiking, but there's no infectious organized. 267 00:14:49,880 --> 00:14:52,280 Speaker 2: It's just they have all these rev duvet cells in them. 268 00:14:52,840 --> 00:14:56,640 Speaker 2: This is a classic example of VIP syndrome, like very 269 00:14:56,640 --> 00:15:01,840 Speaker 2: important person syndrome, where doctors will well do weird stuff 270 00:15:02,080 --> 00:15:06,360 Speaker 2: for people that like you wouldn't do for an ordinary person, 271 00:15:06,400 --> 00:15:11,480 Speaker 2: and actually it probably harms the VVIP. This definitely happens. 272 00:15:11,960 --> 00:15:15,360 Speaker 1: All right, with that, let's turn back to pregnancy brain. 273 00:15:20,720 --> 00:15:24,200 Speaker 2: All right, we're back with what's the deal with pregnancy brain? 274 00:15:24,320 --> 00:15:27,560 Speaker 2: And we're so excited to welcome Alison Williams back to 275 00:15:27,600 --> 00:15:28,240 Speaker 2: discuss with us. 276 00:15:28,640 --> 00:15:31,200 Speaker 4: Hi, I'm happy to be back. I'm sure all of 277 00:15:31,200 --> 00:15:33,680 Speaker 4: that health news was fascinating. 278 00:15:37,280 --> 00:15:41,600 Speaker 3: Okay, so we're going to talk today about pregnancy brain. 279 00:15:42,440 --> 00:15:45,040 Speaker 3: We're going to talk about our personal experience with this, 280 00:15:45,120 --> 00:15:50,080 Speaker 3: but also scientifically about what happens to the brain during pregnancy. 281 00:15:50,280 --> 00:15:52,480 Speaker 3: And I think the way I would like to structure 282 00:15:52,640 --> 00:15:57,760 Speaker 3: answering your questions, Allison, are to start by talking about 283 00:15:57,880 --> 00:16:01,080 Speaker 3: literally what do we know happens to the brain, and 284 00:16:01,160 --> 00:16:03,400 Speaker 3: then talk about how that connects to some of these 285 00:16:03,400 --> 00:16:06,520 Speaker 3: things like ADHD or postpartum depression, and how we can 286 00:16:06,600 --> 00:16:13,040 Speaker 3: separate diagnosis from actual changes from life circumstance changes and 287 00:16:13,080 --> 00:16:16,520 Speaker 3: hopefully get to the bottom of it. So I want 288 00:16:16,560 --> 00:16:20,960 Speaker 3: to start with the fact that your brain shrinks during pregnancy. 289 00:16:21,280 --> 00:16:24,800 Speaker 3: That is my first most interesting fact. And Perry, since 290 00:16:24,800 --> 00:16:28,160 Speaker 3: you're the doctor here but not have never been pregnant, 291 00:16:28,200 --> 00:16:28,680 Speaker 3: please tell. 292 00:16:28,640 --> 00:16:30,440 Speaker 4: Us why did you do this in us? 293 00:16:30,560 --> 00:16:32,120 Speaker 1: Our brain size is what's wrong with you? 294 00:16:32,120 --> 00:16:33,720 Speaker 4: Why did you decide to do that to us? 295 00:16:34,600 --> 00:16:38,000 Speaker 2: I'm going to spin this in the most positive way 296 00:16:38,640 --> 00:16:41,360 Speaker 2: I can. I mean, if you're listening at the top 297 00:16:41,360 --> 00:16:46,160 Speaker 2: of the episode, like, pregnancy is a complete physiologic disaster, 298 00:16:46,440 --> 00:16:47,920 Speaker 2: but let me let me put a number on it. 299 00:16:48,160 --> 00:16:53,640 Speaker 2: The estrogen level of a premenopausal woman, you know, varies 300 00:16:53,680 --> 00:16:55,520 Speaker 2: over the course of the month, but like, let's say 301 00:16:55,560 --> 00:17:00,280 Speaker 2: it's four hundred peekograms per mile leader, so okay, four hundred. 302 00:17:00,720 --> 00:17:05,439 Speaker 2: In the third trimester of pregnancy, it's thirty thousand. It 303 00:17:05,520 --> 00:17:11,160 Speaker 2: is absolutely insane, and for the men, because like it's 304 00:17:11,200 --> 00:17:13,040 Speaker 2: about time someone speaks for the men when it comes 305 00:17:13,080 --> 00:17:13,680 Speaker 2: to pregnancy. 306 00:17:13,760 --> 00:17:15,320 Speaker 4: Thank you for doing this every time too. 307 00:17:15,359 --> 00:17:15,880 Speaker 2: I'm so brief. 308 00:17:15,920 --> 00:17:17,119 Speaker 4: You got a center the right people. 309 00:17:17,960 --> 00:17:21,760 Speaker 2: Men. Do you remember the testosterone replacement therapy episode where 310 00:17:21,760 --> 00:17:25,160 Speaker 2: we pointed out that anabolic steroids like the kind you're 311 00:17:25,320 --> 00:17:28,960 Speaker 2: juicing with are just synthetic forms of testosterone that are 312 00:17:29,000 --> 00:17:33,560 Speaker 2: about ten times more potent, and that ten times increase 313 00:17:33,600 --> 00:17:37,199 Speaker 2: in testosterone level causes muscles to grow. But also, you know, 314 00:17:37,359 --> 00:17:39,720 Speaker 2: liver disease and heart disease, and roid rage and hair 315 00:17:39,800 --> 00:17:42,440 Speaker 2: loss and acne and all these hot, horrible things. That's 316 00:17:42,680 --> 00:17:47,719 Speaker 2: ten times the baseline level of your sort of standard 317 00:17:47,920 --> 00:17:52,240 Speaker 2: hormone pregnancy is one hundred times higher. It's insane. You 318 00:17:52,320 --> 00:17:56,720 Speaker 2: asked about brain shrinkage. The positive spin on this is yet, 319 00:17:56,760 --> 00:18:00,439 Speaker 2: So this is true. This is based on actually several 320 00:18:00,440 --> 00:18:03,760 Speaker 2: studies that have used MRIs and other techniques, and it 321 00:18:03,840 --> 00:18:06,200 Speaker 2: finds about a four and a half to five percent 322 00:18:06,320 --> 00:18:10,720 Speaker 2: decrease in gray matter, which is like the literally the 323 00:18:10,800 --> 00:18:15,840 Speaker 2: neurons in your brain over the course of pregnancy. The 324 00:18:15,880 --> 00:18:20,520 Speaker 2: thought is that pregnancy is actually a neuroplasticity event. The 325 00:18:20,560 --> 00:18:25,480 Speaker 2: brain is cutting a bunch of connections that had existed 326 00:18:25,560 --> 00:18:28,760 Speaker 2: to essentially make room for a slew of new connections, 327 00:18:28,800 --> 00:18:33,080 Speaker 2: including the ones that will lead to, like the social 328 00:18:33,160 --> 00:18:35,480 Speaker 2: interaction with the child, which is going to become such 329 00:18:35,520 --> 00:18:38,719 Speaker 2: an important thing to the brain once delivery happens. So 330 00:18:39,480 --> 00:18:41,560 Speaker 2: it might not just be that you're sitting in a 331 00:18:41,600 --> 00:18:45,400 Speaker 2: toxic stew of hormones for the last three months of pregnancy. 332 00:18:45,400 --> 00:18:48,960 Speaker 2: It might actually be evolutionary indicated so that your brain 333 00:18:49,040 --> 00:18:51,840 Speaker 2: is ready to bond better with your child. 334 00:18:51,920 --> 00:18:53,840 Speaker 3: What do you think, M I feel like this is 335 00:18:54,080 --> 00:18:55,919 Speaker 3: this is like it's cutting all the parts of the 336 00:18:55,960 --> 00:18:58,919 Speaker 3: brain that like, you know, knew how to like go 337 00:18:59,040 --> 00:19:06,760 Speaker 3: out to the club, and then replacing the parts that are. 338 00:19:06,119 --> 00:19:09,720 Speaker 4: Medical explanation for losing those parts of the brain much earlier, 339 00:19:10,840 --> 00:19:13,760 Speaker 4: if the parts of the brain that were like you 340 00:19:13,800 --> 00:19:16,840 Speaker 4: don't need to cry right now. This is really good. 341 00:19:18,160 --> 00:19:21,240 Speaker 3: But a question that I have wondered about and I 342 00:19:21,280 --> 00:19:25,320 Speaker 3: think is sort of in here is like you we 343 00:19:25,359 --> 00:19:27,120 Speaker 3: are not using all of our brain all the time, 344 00:19:27,359 --> 00:19:29,240 Speaker 3: so we are not using all of them. 345 00:19:29,680 --> 00:19:29,919 Speaker 1: You know. 346 00:19:30,000 --> 00:19:31,480 Speaker 3: This is the fact that you're told as a kid 347 00:19:31,640 --> 00:19:33,240 Speaker 3: is like you only ever use ten percent of your 348 00:19:33,280 --> 00:19:35,080 Speaker 3: brain and most of it just sits around or whatever. 349 00:19:35,960 --> 00:19:39,000 Speaker 1: I'm not really sure if that's true, but I don't 350 00:19:39,000 --> 00:19:40,200 Speaker 1: think it's true. 351 00:19:40,200 --> 00:19:42,280 Speaker 2: But you're right there, like we're not using all of 352 00:19:42,280 --> 00:19:43,560 Speaker 2: our brain at every second. 353 00:19:43,640 --> 00:19:45,840 Speaker 3: Yeah, but when we shrink our brain by five percent, 354 00:19:46,320 --> 00:19:48,600 Speaker 3: like is that a meaningful number? This gets to some 355 00:19:48,640 --> 00:19:50,479 Speaker 3: of the broader questions of like is it just like 356 00:19:50,480 --> 00:19:53,439 Speaker 3: it's shrinking and kind of in ways that are not 357 00:19:53,480 --> 00:19:56,159 Speaker 3: that important, or is it shrinking in ways that are meaningful? Alison, 358 00:19:56,200 --> 00:20:01,920 Speaker 3: I'm curious whether you felt during pregnancy. I know we're 359 00:20:01,920 --> 00:20:04,040 Speaker 3: talking about after, but like, did you feel during pregnancy 360 00:20:04,040 --> 00:20:05,000 Speaker 3: that your brain was drinking? 361 00:20:06,280 --> 00:20:08,960 Speaker 4: I started to I didn't feel it for the first 362 00:20:09,680 --> 00:20:12,920 Speaker 4: two trimesters, but by the end I was like, I'm 363 00:20:12,920 --> 00:20:15,280 Speaker 4: not in my body, I'm not in my brain. I 364 00:20:15,680 --> 00:20:16,480 Speaker 4: who's amygdala? 365 00:20:16,600 --> 00:20:16,800 Speaker 2: Is this? 366 00:20:17,080 --> 00:20:22,320 Speaker 4: Like everything fell foreign? And also I'm not a hyper 367 00:20:22,359 --> 00:20:25,280 Speaker 4: emotional person, and Emily, I know you're deeply emotional, so 368 00:20:25,480 --> 00:20:28,000 Speaker 4: this might be hard to really too. That was a 369 00:20:28,080 --> 00:20:31,760 Speaker 4: joke because I'm sort of like wishing we had a 370 00:20:31,800 --> 00:20:35,000 Speaker 4: deeply emotional person here to represent what that's like, because 371 00:20:35,119 --> 00:20:38,800 Speaker 4: I can't imagine what that would be like. But I 372 00:20:38,960 --> 00:20:42,200 Speaker 4: just have this one snapshot of me about two weeks 373 00:20:42,240 --> 00:20:45,240 Speaker 4: shy of delivering. When I made myself pasta and when 374 00:20:45,280 --> 00:20:47,199 Speaker 4: I took it off the stove, I just dumped it 375 00:20:47,280 --> 00:20:51,560 Speaker 4: into the sink without a calendar. I don't cook a lot, obviously, 376 00:20:52,000 --> 00:20:55,960 Speaker 4: and I burst into tears. I was like, this is 377 00:20:56,000 --> 00:21:01,480 Speaker 4: an unfixable problem, like that time is gone, that pasta's gone. 378 00:21:01,880 --> 00:21:05,560 Speaker 4: I just was like weeping in the kitchen, sort of 379 00:21:05,600 --> 00:21:08,919 Speaker 4: like paralyzed with the inability to decide what to do next, 380 00:21:09,080 --> 00:21:11,919 Speaker 4: like lacking all the skills to handle this situation. I 381 00:21:11,960 --> 00:21:14,679 Speaker 4: felt like a little kid again. And that is a 382 00:21:14,680 --> 00:21:17,800 Speaker 4: moment where I felt just like I want all of 383 00:21:17,880 --> 00:21:21,000 Speaker 4: my old machinery back, and I never got it back, 384 00:21:21,240 --> 00:21:25,240 Speaker 4: like I got new stuff. I feel like when I 385 00:21:25,320 --> 00:21:28,200 Speaker 4: lost the five percent, it didn't that same five percent 386 00:21:28,240 --> 00:21:33,280 Speaker 4: didn't just come back. It was you know, it was different. 387 00:21:34,400 --> 00:21:36,000 Speaker 2: Yeah, something fundamentally changed. 388 00:21:36,359 --> 00:21:36,639 Speaker 5: Yeah. 389 00:21:37,040 --> 00:21:42,000 Speaker 3: Yeah, So I think this connects to the second piece here, 390 00:21:42,040 --> 00:21:46,480 Speaker 3: which is what happens to measured cognitive function in the data, 391 00:21:46,480 --> 00:21:48,199 Speaker 3: because it's one thing to sort of say, Okay, the 392 00:21:48,240 --> 00:21:50,320 Speaker 3: brain shrinks and then it comes back to normal, and 393 00:21:50,359 --> 00:21:52,280 Speaker 3: it maybe come back to normal in a different with 394 00:21:52,359 --> 00:21:54,720 Speaker 3: a sort of different set of connections. But there was 395 00:21:54,760 --> 00:21:57,240 Speaker 3: also a fair amount of research about sort of during 396 00:21:57,359 --> 00:22:04,800 Speaker 3: pregnancy specific declines and cognitive function in memory and executive function. 397 00:22:06,000 --> 00:22:09,879 Speaker 3: A lot of this is about kind of processing speed 398 00:22:10,160 --> 00:22:12,879 Speaker 3: and these sort of measures of like just how how 399 00:22:12,960 --> 00:22:14,399 Speaker 3: much stuck can you hold in your brain at the 400 00:22:14,400 --> 00:22:16,679 Speaker 3: same time, and how good is your verbal memory. 401 00:22:16,680 --> 00:22:18,800 Speaker 1: That's like a common way to measure this. 402 00:22:19,160 --> 00:22:22,440 Speaker 3: And I think this will this illustrates to me a 403 00:22:22,520 --> 00:22:26,000 Speaker 3: general problem with all of these discussions, which is that 404 00:22:26,040 --> 00:22:28,399 Speaker 3: there's there's something we can measure, which is how is 405 00:22:28,440 --> 00:22:32,400 Speaker 3: your brain actually changing? And then if we measure some change, 406 00:22:32,520 --> 00:22:35,720 Speaker 3: we then want to say, like why we want toust 407 00:22:35,760 --> 00:22:38,520 Speaker 3: so story about like either it's because of the hormones 408 00:22:38,520 --> 00:22:41,920 Speaker 3: all in the brain, or it could be because you're tired, 409 00:22:42,359 --> 00:22:44,600 Speaker 3: or because because you're paying attention to it, or it 410 00:22:44,600 --> 00:22:46,840 Speaker 3: could be because like you're thinking about a lot of 411 00:22:46,840 --> 00:22:48,920 Speaker 3: different things and there's a lot of new stimuli and 412 00:22:48,960 --> 00:22:51,280 Speaker 3: like you know, when you poured the pasta in the sink. 413 00:22:51,320 --> 00:22:52,760 Speaker 1: It wasn't because you got stupider. 414 00:22:52,840 --> 00:22:54,600 Speaker 3: It was because you were also thinking about how you 415 00:22:54,760 --> 00:22:58,400 Speaker 3: like had to buy a crib and uh, and you. 416 00:22:58,359 --> 00:22:59,240 Speaker 1: Hadn't gotten enough sleep. 417 00:22:59,240 --> 00:23:01,520 Speaker 3: So I think the like in all of this stuff, 418 00:23:01,560 --> 00:23:03,720 Speaker 3: it's going to be incredibly difficult to separate the like 419 00:23:03,800 --> 00:23:07,439 Speaker 3: life circumstance change from the sort of some kind of 420 00:23:07,520 --> 00:23:09,720 Speaker 3: true biological parameter. 421 00:23:10,480 --> 00:23:12,560 Speaker 2: And we've also talked before about how hard it is 422 00:23:12,600 --> 00:23:15,800 Speaker 2: to measure the something that we all understand conceptually, like 423 00:23:15,840 --> 00:23:17,679 Speaker 2: brain fog, whatever you want to call it, right, like 424 00:23:17,720 --> 00:23:21,720 Speaker 2: pregnancy brain, brain fog, you know, baby brain, these subjective 425 00:23:21,760 --> 00:23:24,159 Speaker 2: states of like I don't feel as smart as I 426 00:23:24,359 --> 00:23:28,000 Speaker 2: normally do. That's there's no test for that, right, there's 427 00:23:28,000 --> 00:23:30,439 Speaker 2: not an IQ test that pulls that out. You have 428 00:23:30,480 --> 00:23:34,480 Speaker 2: to do all this really specific neurocognitive testing, you know, 429 00:23:34,600 --> 00:23:36,760 Speaker 2: to see if there are problems with like, oh, your 430 00:23:36,840 --> 00:23:39,359 Speaker 2: verbal memory, which is, you know, can you think of 431 00:23:39,400 --> 00:23:43,280 Speaker 2: the word for calender? Or your semantic memory, which is 432 00:23:43,359 --> 00:23:46,040 Speaker 2: like do you know who fought in the War of 433 00:23:46,080 --> 00:23:49,119 Speaker 2: eighteen twelve? Like, these are actually different things and they 434 00:23:49,160 --> 00:23:53,560 Speaker 2: get teased out differently. Can I tell my wife's pregnancy 435 00:23:53,560 --> 00:23:56,520 Speaker 2: brain story because I think it illustrates this really nicely. 436 00:23:56,600 --> 00:23:59,879 Speaker 2: So my wife is a breast cancer surgeon and she 437 00:24:00,119 --> 00:24:04,320 Speaker 2: is in the operating room, very pregnant with our second 438 00:24:04,720 --> 00:24:07,160 Speaker 2: and you've probably seen this on TV, but it's it's 439 00:24:07,160 --> 00:24:09,240 Speaker 2: literally true. Like if you're the surgeon, you don't want 440 00:24:09,240 --> 00:24:11,720 Speaker 2: to look away from the field, like you're looking down 441 00:24:11,760 --> 00:24:14,280 Speaker 2: into the operating field, and so you just stick your 442 00:24:14,280 --> 00:24:16,280 Speaker 2: hand out without looking and you say the name of 443 00:24:16,320 --> 00:24:20,160 Speaker 2: the instrument you want, right like you want an adsons retractor, 444 00:24:20,320 --> 00:24:22,760 Speaker 2: or you want, you know, a debate or whatever it is. 445 00:24:23,080 --> 00:24:24,040 Speaker 2: They have these names. 446 00:24:24,240 --> 00:24:25,360 Speaker 4: I was going to say the same thing. 447 00:24:25,680 --> 00:24:28,160 Speaker 1: Yeah, yeah, the ones. I'm actually holding those right now? 448 00:24:29,280 --> 00:24:33,320 Speaker 2: How many My destra full of debate's right here? And 449 00:24:33,760 --> 00:24:35,919 Speaker 2: the scrup text job is they're standing with all the 450 00:24:35,920 --> 00:24:38,320 Speaker 2: clean instruments, is to hand you the thing that you 451 00:24:38,359 --> 00:24:40,840 Speaker 2: ask for, or to anticipate the thing that you ask for. 452 00:24:41,040 --> 00:24:43,800 Speaker 2: And she was having this situation where she's like in there, 453 00:24:43,840 --> 00:24:46,680 Speaker 2: she's operating, and she holds her hand out and she's 454 00:24:46,800 --> 00:24:51,439 Speaker 2: like the the thing you know with the one with 455 00:24:51,480 --> 00:24:54,840 Speaker 2: the teeth, the thing you know, and the scrub tech 456 00:24:55,440 --> 00:24:58,920 Speaker 2: because scrub techs are amazing, handed her the proper instrument, 457 00:24:59,359 --> 00:25:01,720 Speaker 2: and you know, they all kind of laughed about it 458 00:25:01,720 --> 00:25:05,160 Speaker 2: because they'd been pregnant too, and it's one of those situations, 459 00:25:05,160 --> 00:25:08,119 Speaker 2: but it illustrated to me. So like operationally, the muscle 460 00:25:08,160 --> 00:25:11,719 Speaker 2: memories there, and all the testing in pregnant women and 461 00:25:11,840 --> 00:25:15,480 Speaker 2: postpartum women suggest that, like physical memory, muscle memory doesn't 462 00:25:15,480 --> 00:25:17,159 Speaker 2: really change. If you can swing a golf club, you 463 00:25:17,160 --> 00:25:19,400 Speaker 2: can still swing a golf club. But so she could 464 00:25:19,400 --> 00:25:21,840 Speaker 2: do the operation just fine, she just couldn't name the 465 00:25:21,920 --> 00:25:25,760 Speaker 2: instrument that she needed at that time. And verbal memory 466 00:25:25,800 --> 00:25:28,120 Speaker 2: is certainly affected during pregnancy and after pregnancy. 467 00:25:29,040 --> 00:25:32,080 Speaker 4: That is fascinating. Yeah, you're literally a surgeon doing a 468 00:25:32,119 --> 00:25:35,040 Speaker 4: surgery and yet you're still not spared. You still have 469 00:25:35,040 --> 00:25:35,680 Speaker 4: a human brain. 470 00:25:36,119 --> 00:25:40,440 Speaker 2: Yeah yeah, Okay, so there are a million physiologic changes 471 00:25:40,600 --> 00:25:43,040 Speaker 2: that happen when you're pregnant, and it might be worth 472 00:25:43,119 --> 00:25:45,920 Speaker 2: just talking about how those things affect your brain. So, 473 00:25:46,560 --> 00:25:49,560 Speaker 2: for example, you might know that there is a forty 474 00:25:49,560 --> 00:25:54,919 Speaker 2: to fifty percent increase in blood volume during pregnancy. So okay, 475 00:25:55,040 --> 00:25:57,840 Speaker 2: that's crazy in and of itself, but what that means 476 00:25:58,000 --> 00:26:02,159 Speaker 2: that volume expansion paces the production of red blood cells, 477 00:26:02,640 --> 00:26:06,840 Speaker 2: which gives some anemia. Pregnant women tend to have you know, 478 00:26:07,000 --> 00:26:10,159 Speaker 2: more anemia, less red blood cell counts, which means not 479 00:26:10,200 --> 00:26:13,719 Speaker 2: as much oxygen carrying capacity not you know, which can 480 00:26:13,720 --> 00:26:17,160 Speaker 2: certainly affect if your brain is firing on all cylinders. 481 00:26:17,680 --> 00:26:21,480 Speaker 2: Let's talk about the cardiovascular changes. So your heart rate 482 00:26:21,600 --> 00:26:25,720 Speaker 2: is up by about thirty to fifty percent during pregnancy. 483 00:26:25,840 --> 00:26:30,280 Speaker 2: This is a big energy expenditure. This takes calories and 484 00:26:30,880 --> 00:26:38,359 Speaker 2: that can contribute to fatigue, reduces cognitive stamina. The respiratory side, 485 00:26:38,520 --> 00:26:41,440 Speaker 2: tidal volume, how much air you breathe in when you 486 00:26:41,520 --> 00:26:46,119 Speaker 2: take a breath, increases during until you until you're restricted 487 00:26:46,119 --> 00:26:49,720 Speaker 2: by belly volume. But for the first few for the 488 00:26:49,720 --> 00:26:52,439 Speaker 2: first couple trimesters, about a thirty to fifty percent increase 489 00:26:52,480 --> 00:26:57,320 Speaker 2: in tidal volume leads to slight hyper ventilation, which means 490 00:26:57,359 --> 00:27:01,160 Speaker 2: your blood carries less carbon dioxide can contribute to feeling 491 00:27:01,240 --> 00:27:05,480 Speaker 2: light headed or dizzy. And one last thing I've mentioned 492 00:27:05,520 --> 00:27:09,480 Speaker 2: several times, just the enormous, enormous surge in hormones. We 493 00:27:09,560 --> 00:27:12,520 Speaker 2: talked a lot about estrogen, but progesterone also goes up 494 00:27:12,560 --> 00:27:18,840 Speaker 2: by about five hundredfold compared to baseline, and progesterone has 495 00:27:18,840 --> 00:27:23,399 Speaker 2: some mild sedative effects. So it's almost as if the 496 00:27:23,440 --> 00:27:29,399 Speaker 2: whole like physiologic state of pregnancy is conspiring to put 497 00:27:29,480 --> 00:27:33,080 Speaker 2: you in a place where your brain is not working well, 498 00:27:33,119 --> 00:27:37,520 Speaker 2: where you're tired, and you know your body is just 499 00:27:37,920 --> 00:27:41,840 Speaker 2: like people sometimes say that the purpose of your body 500 00:27:41,880 --> 00:27:43,760 Speaker 2: is to get your brain from one place to another, right, 501 00:27:43,800 --> 00:27:45,520 Speaker 2: like your body is to support your brain. You are 502 00:27:45,600 --> 00:27:49,359 Speaker 2: your brain. Well, true, except during pregnancy, when the body 503 00:27:49,440 --> 00:27:52,679 Speaker 2: just decides screw your brain. I'm focusing on the baby. 504 00:27:53,600 --> 00:27:56,359 Speaker 3: Okay, let's talk about the two good things about brains 505 00:27:56,400 --> 00:28:00,680 Speaker 3: before we talk about postpartum changes. So why is that 506 00:28:01,000 --> 00:28:06,320 Speaker 3: while your brain is remapping you get better at recognizing 507 00:28:06,600 --> 00:28:09,479 Speaker 3: recognition tasks. So if we sort of think about the 508 00:28:09,520 --> 00:28:11,960 Speaker 3: pieces that you don't that you need to be don't 509 00:28:12,000 --> 00:28:14,720 Speaker 3: need to be as good at, like going to the 510 00:28:14,760 --> 00:28:17,600 Speaker 3: club or whatever, then there's a set of things you 511 00:28:17,640 --> 00:28:20,080 Speaker 3: need to be better at in evolutionary standpoint, which is 512 00:28:20,119 --> 00:28:23,120 Speaker 3: like recognizing threats. And so we do see some evidence 513 00:28:23,160 --> 00:28:26,520 Speaker 3: that people get better at sort of differentiating between like 514 00:28:26,600 --> 00:28:30,639 Speaker 3: known and unknown faces in pregnancy, which may have some 515 00:28:30,840 --> 00:28:34,960 Speaker 3: beneficial ability to recognize who is you know, an outgroup 516 00:28:35,000 --> 00:28:36,520 Speaker 3: and in a group member and who do you want 517 00:28:36,520 --> 00:28:38,360 Speaker 3: to trust more with your baby. 518 00:28:38,800 --> 00:28:42,400 Speaker 2: That's super fascinating that I always feel like so much 519 00:28:42,440 --> 00:28:44,960 Speaker 2: of the things we think of as our own thoughts 520 00:28:44,960 --> 00:28:47,400 Speaker 2: and emotions are just like the monkey inside of us 521 00:28:47,640 --> 00:28:48,520 Speaker 2: doing monkey things. 522 00:28:49,000 --> 00:28:51,440 Speaker 3: Yeah, I think that's true, But then I also think 523 00:28:51,560 --> 00:28:53,920 Speaker 3: it's so easy to write just so stories about evolution. 524 00:28:54,040 --> 00:28:56,400 Speaker 3: We're just like, well, I guess evolution is why that happened. 525 00:28:56,760 --> 00:28:58,840 Speaker 3: It often is the Culpridge generally true. 526 00:28:58,880 --> 00:29:01,760 Speaker 4: But I also feel like when you were saying this 527 00:29:01,840 --> 00:29:04,800 Speaker 4: is like a medical disaster pregnancy, I've been saying this 528 00:29:04,800 --> 00:29:06,600 Speaker 4: for a long time, Like I have so many notes 529 00:29:06,800 --> 00:29:11,040 Speaker 4: for like whoever's in charge for Charles Darwin? I guess 530 00:29:11,400 --> 00:29:16,640 Speaker 4: because I'm like, why do men have nipples? Why do 531 00:29:17,080 --> 00:29:18,280 Speaker 4: I have pinky toes? 532 00:29:18,480 --> 00:29:19,000 Speaker 5: Why? 533 00:29:19,320 --> 00:29:23,560 Speaker 4: Like why you know all of these things appendices like 534 00:29:23,640 --> 00:29:28,479 Speaker 4: we don't need? And why are children brought into the 535 00:29:28,520 --> 00:29:32,600 Speaker 4: earth the way they are? Why is there no new 536 00:29:32,720 --> 00:29:38,680 Speaker 4: way a velcrow opening perhaps, or a zipper or a 537 00:29:38,720 --> 00:29:41,720 Speaker 4: magic Wand like as I approach childbirth, I was like, 538 00:29:41,760 --> 00:29:46,120 Speaker 4: is there honestly no like VIP secret third way to 539 00:29:46,240 --> 00:29:48,440 Speaker 4: do this? Who do I have to talk to to 540 00:29:48,560 --> 00:29:51,280 Speaker 4: not go through either of these situations? 541 00:29:51,360 --> 00:29:55,120 Speaker 2: This is so geeky of me. But I remember watching 542 00:29:55,120 --> 00:29:57,440 Speaker 2: Star Trek when I was younger, and they would have 543 00:29:57,520 --> 00:29:59,240 Speaker 2: every once in a while, like someone would be pregnant, 544 00:29:59,760 --> 00:30:02,600 Speaker 2: and and I was like, why don't they just transport 545 00:30:02,600 --> 00:30:06,480 Speaker 2: the baby out like we're speming people down to the planet. Why, 546 00:30:06,760 --> 00:30:09,000 Speaker 2: Like what, how is this not? Is this not the 547 00:30:09,040 --> 00:30:09,400 Speaker 2: main thing? 548 00:30:09,440 --> 00:30:12,000 Speaker 4: That's what I want my tax dollars going towards. It's 549 00:30:12,040 --> 00:30:14,120 Speaker 4: the hovercraft from Back to the Future that we were 550 00:30:14,240 --> 00:30:15,760 Speaker 4: promised and has not appeared. 551 00:30:15,760 --> 00:30:17,640 Speaker 1: We're told, where is that we're told? 552 00:30:18,120 --> 00:30:21,520 Speaker 4: And I want to be able to like disaporate my child, 553 00:30:21,640 --> 00:30:26,080 Speaker 4: to use Harry Potter verbit from my belly into the world. 554 00:30:26,880 --> 00:30:30,640 Speaker 4: But I also think about the fact that evolutionarily, also 555 00:30:30,680 --> 00:30:32,280 Speaker 4: because I have a four and a half year old, 556 00:30:32,280 --> 00:30:34,480 Speaker 4: we talking about dinosaurs all the time. We've been around 557 00:30:34,520 --> 00:30:39,120 Speaker 4: for a tiny blip of history, but like a triceratops, 558 00:30:39,160 --> 00:30:42,640 Speaker 4: by the time they were extinct was like peak. Triceratops 559 00:30:42,680 --> 00:30:45,640 Speaker 4: had had millions of years to become the best version. 560 00:30:45,440 --> 00:30:48,080 Speaker 2: Of saying we're not done yet, We've got. 561 00:30:47,720 --> 00:30:51,880 Speaker 3: And we're gonna still the triceratops was not disaporating the 562 00:30:51,920 --> 00:30:53,040 Speaker 3: baby out, but. 563 00:30:53,000 --> 00:30:56,120 Speaker 2: Well, that's right. Wasn't it egg laying? According to Jurassic Park? 564 00:30:56,160 --> 00:30:57,000 Speaker 2: I know nothing about. 565 00:30:57,080 --> 00:31:01,360 Speaker 4: Eratops Jurassic Park, Yeah, triceratog. 566 00:31:00,800 --> 00:31:02,160 Speaker 2: Which also seems like a better way. 567 00:31:02,280 --> 00:31:03,600 Speaker 4: We're aggling. Yeah, that's right. 568 00:31:03,880 --> 00:31:04,760 Speaker 2: I mean, if it's small. 569 00:31:05,440 --> 00:31:09,560 Speaker 3: My worst pregnancy dream was one where the baby did 570 00:31:09,680 --> 00:31:13,040 Speaker 3: just come out and then but it was like too early, 571 00:31:13,080 --> 00:31:14,440 Speaker 3: and then I had to like get it back in 572 00:31:15,440 --> 00:31:18,520 Speaker 3: and like it just but it came out just like 573 00:31:18,520 --> 00:31:20,600 Speaker 3: like open like a velcro, you know now, like caseful, 574 00:31:20,640 --> 00:31:22,280 Speaker 3: and just like velcrode itself out, and then I had 575 00:31:22,280 --> 00:31:23,800 Speaker 3: to be like, no, no, no, it's not time yet, like 576 00:31:23,800 --> 00:31:24,440 Speaker 3: put it back in. 577 00:31:26,120 --> 00:31:29,920 Speaker 2: Do you know that humans have babies way earlier than 578 00:31:29,960 --> 00:31:33,280 Speaker 2: they should according to our body size and level of 579 00:31:33,280 --> 00:31:36,280 Speaker 2: fetal development, Like we should be pregnant for several more 580 00:31:36,320 --> 00:31:40,280 Speaker 2: months and and we're not because our brains are so 581 00:31:40,400 --> 00:31:41,440 Speaker 2: big that they. 582 00:31:41,280 --> 00:31:46,040 Speaker 4: Have called the cranial it's there's a name for it, 583 00:31:46,480 --> 00:31:50,680 Speaker 4: a conundrum among because yes, evolutionarily, like our hip size 584 00:31:51,400 --> 00:31:55,120 Speaker 4: versus our brain size have forced us into a what 585 00:31:55,240 --> 00:31:57,200 Speaker 4: is it called? Do you remember? I don't want to 586 00:31:57,240 --> 00:32:00,760 Speaker 4: be born into Homo sapiens now, I want to do 587 00:32:00,800 --> 00:32:03,280 Speaker 4: it in one hundred million years when we are like 588 00:32:04,160 --> 00:32:06,080 Speaker 4: peak homosapiens. 589 00:32:06,640 --> 00:32:08,840 Speaker 1: Okay, anyway, sorry, I got all right. 590 00:32:11,080 --> 00:32:13,520 Speaker 3: Let us come back to our pregnancy brain because I 591 00:32:13,600 --> 00:32:18,360 Speaker 3: want to come back to the post pregnancy period because 592 00:32:18,680 --> 00:32:22,640 Speaker 3: many of these like physiological issues that happen during pregnancy 593 00:32:22,680 --> 00:32:26,720 Speaker 3: actually do sort of resolve post pregnancy. So your brain 594 00:32:26,800 --> 00:32:29,720 Speaker 3: grows back differently, but it gets it's five percent back. 595 00:32:30,240 --> 00:32:34,360 Speaker 3: And there's actually some super interesting research about the like 596 00:32:35,400 --> 00:32:40,600 Speaker 3: age of your brain as measured by brain age researchers postpartum. 597 00:32:40,760 --> 00:32:43,480 Speaker 3: So in the period from like like two weeks postpartum 598 00:32:43,520 --> 00:32:46,200 Speaker 3: to like three months postpartum, your brain actually ages backwards 599 00:32:46,280 --> 00:32:49,840 Speaker 3: quite quickly. And so whatever sort of aid terrible aging 600 00:32:49,920 --> 00:32:52,560 Speaker 3: was occurring during pregnancy, you like get some. 601 00:32:52,600 --> 00:32:54,720 Speaker 1: Of it backs postpartum. 602 00:32:54,760 --> 00:32:57,000 Speaker 3: And so there's this sort of feeling of like things 603 00:32:57,040 --> 00:33:02,000 Speaker 3: are kind of returning brain in some way. And yet 604 00:33:02,000 --> 00:33:04,880 Speaker 3: this is also a period in which we see a 605 00:33:04,920 --> 00:33:08,440 Speaker 3: lot of we see postpartum depression, we see postpartum anxiety, 606 00:33:08,520 --> 00:33:12,000 Speaker 3: we see potentially changes in other kinds of diagnoses, And 607 00:33:12,040 --> 00:33:16,640 Speaker 3: I think that is that's this sort of secondary period, 608 00:33:16,760 --> 00:33:21,480 Speaker 3: and it's really hard to separate how much of those 609 00:33:21,600 --> 00:33:25,720 Speaker 3: changes are about actual brain changes and how much of 610 00:33:25,760 --> 00:33:29,440 Speaker 3: those changes are about like almost a diagnosis window where 611 00:33:29,440 --> 00:33:31,160 Speaker 3: you're seeing people more. 612 00:33:31,160 --> 00:33:36,080 Speaker 2: And there's no neuroanatomical correlate of depression, like even putting 613 00:33:36,080 --> 00:33:38,840 Speaker 2: a side postpartum depression. You can't take people with major 614 00:33:38,880 --> 00:33:41,680 Speaker 2: depressive disorder and put them in an MRI scanner and 615 00:33:41,760 --> 00:33:45,560 Speaker 2: see significant differences in brain structure. I mean, there are 616 00:33:45,600 --> 00:33:47,520 Speaker 2: some experiments that are trying to tease this out, but 617 00:33:47,560 --> 00:33:51,400 Speaker 2: it really is about the connectivity and the interactions between 618 00:33:51,400 --> 00:33:54,600 Speaker 2: brain regions that drive these things, which means like a 619 00:33:54,640 --> 00:33:56,680 Speaker 2: simple test like how big is your brain, how small 620 00:33:56,800 --> 00:33:59,760 Speaker 2: you know, whatever, is not going to be enough. 621 00:34:00,280 --> 00:34:02,680 Speaker 3: Yeah, all right, So let's talk about postpartum depression and 622 00:34:02,680 --> 00:34:07,120 Speaker 3: postpartum anxiety first because these are probably the main primary 623 00:34:07,160 --> 00:34:10,000 Speaker 3: diagnoses that people get. So, Allison, you said you had 624 00:34:10,000 --> 00:34:13,600 Speaker 3: postpardon depression. Can you talk about that? Are you open 625 00:34:13,600 --> 00:34:14,040 Speaker 3: to talking? 626 00:34:14,200 --> 00:34:17,640 Speaker 4: Yeah? I never, I'm an anxiety girlie. So that's the 627 00:34:17,680 --> 00:34:19,840 Speaker 4: side of the street I was familiar with. But so 628 00:34:19,920 --> 00:34:22,719 Speaker 4: I had never, I don't think, been in a depression 629 00:34:22,960 --> 00:34:26,280 Speaker 4: in my life, so I didn't actually identify it until 630 00:34:26,320 --> 00:34:28,399 Speaker 4: I was out of it, which is apparently a very 631 00:34:28,440 --> 00:34:32,840 Speaker 4: common thing. Because you're just getting through it. And also 632 00:34:34,840 --> 00:34:37,319 Speaker 4: those early months and weeks of motherhood are such a 633 00:34:37,360 --> 00:34:42,600 Speaker 4: subjective experience that it's one of the few moments in 634 00:34:42,600 --> 00:34:47,960 Speaker 4: life where you can exchange techniques, data, concrete information. But 635 00:34:48,280 --> 00:34:53,760 Speaker 4: trading experience stories is not an impulse I had until 636 00:34:53,880 --> 00:34:57,680 Speaker 4: I was through it, whereas now I get a ton 637 00:34:57,719 --> 00:35:01,200 Speaker 4: of I don't know, satisfaction from talking about something I'm 638 00:35:01,239 --> 00:35:03,560 Speaker 4: dealing with in this exact moment as a parent with 639 00:35:03,640 --> 00:35:06,600 Speaker 4: my friends who are also going through it. There's a reporting, 640 00:35:06,680 --> 00:35:09,480 Speaker 4: live factor that I was not able to channel in 641 00:35:09,520 --> 00:35:11,759 Speaker 4: the moment, and I think part of it is a 642 00:35:12,520 --> 00:35:14,880 Speaker 4: it felt like a valve was switched in my brain 643 00:35:14,920 --> 00:35:18,200 Speaker 4: that was like, no need to overthink any of this, 644 00:35:18,600 --> 00:35:23,200 Speaker 4: just get through it. And what was happening was just overwhelming. Emotionally, 645 00:35:23,280 --> 00:35:28,840 Speaker 4: it was a lot of instances of just real feeling 646 00:35:29,280 --> 00:35:35,839 Speaker 4: very disconnected from my son, initially, feeling very alone, very isolated, 647 00:35:36,080 --> 00:35:43,600 Speaker 4: and despite having family nearby, a super supportive, loving husband, therapist, 648 00:35:43,840 --> 00:35:46,480 Speaker 4: like I had kind of all the resources you can have, 649 00:35:46,520 --> 00:35:49,959 Speaker 4: we did not have nanny or a night nurse or anything, 650 00:35:50,000 --> 00:35:54,719 Speaker 4: so I also was dealing with sleep deprivation. But I 651 00:35:54,920 --> 00:36:00,600 Speaker 4: just it just felt like everything was devasa and I 652 00:36:00,600 --> 00:36:05,200 Speaker 4: would very often sit on the couch where I was 653 00:36:05,360 --> 00:36:07,839 Speaker 4: constantly breastfeeding our son, and I have this like very 654 00:36:08,000 --> 00:36:10,279 Speaker 4: clear example of what it felt like to be in 655 00:36:10,320 --> 00:36:13,840 Speaker 4: my body. My husband would come like flying through the hallway, 656 00:36:14,120 --> 00:36:17,640 Speaker 4: like doing his twelfth load of laundry, and he'd be like, 657 00:36:17,680 --> 00:36:20,200 Speaker 4: do you need me to refill your water? And like 658 00:36:20,320 --> 00:36:24,120 Speaker 4: time would stop, and then like ten minutes later, I 659 00:36:24,160 --> 00:36:29,560 Speaker 4: would have done the complicated trigonometry to answer the question, 660 00:36:29,880 --> 00:36:32,560 Speaker 4: because what my brain was doing was, Okay, yes, my 661 00:36:32,640 --> 00:36:35,600 Speaker 4: water bottle is empty, but I want to be self sufficient. 662 00:36:35,640 --> 00:36:37,000 Speaker 4: I want to be the kind of person that can 663 00:36:37,040 --> 00:36:39,560 Speaker 4: fill my own water bottle, but I'm breastfeeding, so I 664 00:36:39,600 --> 00:36:41,319 Speaker 4: can't and it'll be a little while and I need 665 00:36:41,360 --> 00:36:44,399 Speaker 4: water to breastfeed. He's standing right there. Oh my god, 666 00:36:44,440 --> 00:36:47,759 Speaker 4: he's so impatient. I'm still thinking this through, shouldn't I be? 667 00:36:47,840 --> 00:36:51,240 Speaker 4: And it was just happening, and I'm a ruminator in general, 668 00:36:51,239 --> 00:36:54,840 Speaker 4: but it was going on twice as long, twice the 669 00:36:54,880 --> 00:37:02,680 Speaker 4: self judgment. It was just like everything was magnified, and slowly, 670 00:37:02,880 --> 00:37:06,200 Speaker 4: after I came out of it, I realized just how 671 00:37:06,360 --> 00:37:11,839 Speaker 4: dark some of those moments were and how difficult it 672 00:37:11,920 --> 00:37:14,239 Speaker 4: is to express them while they're happening. And I think 673 00:37:14,239 --> 00:37:16,960 Speaker 4: that's part of what makes it so gnarly, is that 674 00:37:17,080 --> 00:37:19,960 Speaker 4: I don't know a ton of women who were able 675 00:37:20,040 --> 00:37:24,960 Speaker 4: to speak from their postpartum depression while it was happening, 676 00:37:25,160 --> 00:37:30,360 Speaker 4: rather than about it in retrospect. But it also sucks 677 00:37:30,400 --> 00:37:33,280 Speaker 4: because you're like, when people ask you how it's going 678 00:37:33,400 --> 00:37:36,640 Speaker 4: or how's the baby, there's a there's one right vibe 679 00:37:36,719 --> 00:37:38,759 Speaker 4: to channel after that question. 680 00:37:38,560 --> 00:37:41,839 Speaker 1: Going great, Yeah, exactly, I love it so much. 681 00:37:42,400 --> 00:37:46,600 Speaker 4: Yes, he's because that's also true. You're completely obsessed with 682 00:37:46,640 --> 00:37:50,640 Speaker 4: this little person who you also are so frustrated with 683 00:37:50,719 --> 00:37:54,960 Speaker 4: sometimes and so exhausted by, and so both things are true, 684 00:37:54,960 --> 00:37:59,200 Speaker 4: and intuitively you just know that. Just give the surface 685 00:37:59,280 --> 00:38:03,640 Speaker 4: level answer and case keep it moving. And I wish 686 00:38:03,719 --> 00:38:07,040 Speaker 4: I had been treated for depression while it was happening. 687 00:38:07,040 --> 00:38:09,959 Speaker 4: I probably should have begun treatment before I delivered, because 688 00:38:10,000 --> 00:38:12,040 Speaker 4: I think it kind of started a little bit before then. 689 00:38:13,160 --> 00:38:17,000 Speaker 4: And yeah, I mean that's sort of what it looked like. 690 00:38:17,040 --> 00:38:19,480 Speaker 4: It's very hard to describe as you just experienced, because 691 00:38:19,520 --> 00:38:23,360 Speaker 4: I talked for like five minutes and said nothing, because 692 00:38:23,360 --> 00:38:25,880 Speaker 4: it's hard to channel that place again. It's hard to 693 00:38:25,880 --> 00:38:28,120 Speaker 4: go back there, but I can just see moments of 694 00:38:28,280 --> 00:38:31,319 Speaker 4: just being completely stuck and feeling like I was underneath 695 00:38:31,520 --> 00:38:34,080 Speaker 4: a wave that I couldn't get up and out of. 696 00:38:35,239 --> 00:38:37,759 Speaker 3: So about half of because we're saying about half of 697 00:38:37,920 --> 00:38:44,279 Speaker 3: postpartum depression starts during pregnancy and so, and that is 698 00:38:44,320 --> 00:38:45,600 Speaker 3: often not screened for. 699 00:38:46,640 --> 00:38:48,399 Speaker 1: And then when you. 700 00:38:48,400 --> 00:38:52,880 Speaker 3: Have the babe this the hormonal changes like this estrogen 701 00:38:52,920 --> 00:38:56,400 Speaker 3: that was like bathing your self for all this last trimester, 702 00:38:56,560 --> 00:39:00,879 Speaker 3: like totally could just tanks off a cliff. And those 703 00:39:00,960 --> 00:39:06,560 Speaker 3: changes are very, very difficult, and so almost everybody, I 704 00:39:06,560 --> 00:39:08,360 Speaker 3: think this is part of the DT the sort of 705 00:39:08,400 --> 00:39:11,719 Speaker 3: diagnosis issue here. Almost everybody has a period of kind 706 00:39:11,760 --> 00:39:15,920 Speaker 3: of quite significant mood changes, like immediately afterwards. 707 00:39:15,760 --> 00:39:18,560 Speaker 4: Yes, my friends were like, beware day three, You're gonna 708 00:39:18,600 --> 00:39:20,560 Speaker 4: just like burst into tears on day three. And then 709 00:39:20,600 --> 00:39:22,680 Speaker 4: I was like, I feel fine. And then twenty minutes 710 00:39:22,760 --> 00:39:25,080 Speaker 4: later I was just bawling and I sent them a 711 00:39:25,080 --> 00:39:27,280 Speaker 4: picture of myself like just weeping for no reason. 712 00:39:27,600 --> 00:39:30,360 Speaker 1: I was like, can stay here. I have many memories 713 00:39:30,400 --> 00:39:31,600 Speaker 1: of that that period. 714 00:39:31,640 --> 00:39:33,919 Speaker 3: And then then for you know, many people, that sort 715 00:39:33,960 --> 00:39:37,200 Speaker 3: of for some people that normalizes and sort of what 716 00:39:37,239 --> 00:39:40,200 Speaker 3: we would really think about as diagnosable. Postpartum depression is 717 00:39:40,440 --> 00:39:43,040 Speaker 3: sort of can then creep up as late as you know, 718 00:39:43,239 --> 00:39:46,400 Speaker 3: almost a year after, you can creep up anytime, but 719 00:39:46,560 --> 00:39:49,560 Speaker 3: sort of can be cidered postpartum depression even up till 720 00:39:49,560 --> 00:39:53,439 Speaker 3: a relatively long period of time afterwards. And I will 721 00:39:53,440 --> 00:39:56,719 Speaker 3: say some of it is as Perry said, like the 722 00:39:56,719 --> 00:39:59,120 Speaker 3: there is no way to put you in an fMRI 723 00:39:59,320 --> 00:40:02,680 Speaker 3: machine or some kind of like blood test and be like, okay, 724 00:40:02,680 --> 00:40:04,520 Speaker 3: this is what you have. And so we are left 725 00:40:04,520 --> 00:40:08,759 Speaker 3: with trying to screen people and give them appropriate treatments. 726 00:40:09,360 --> 00:40:11,880 Speaker 3: But it really in some ways doesn't matter whether you 727 00:40:12,000 --> 00:40:14,360 Speaker 3: diagnosed or not, Like, if you have this consolation of symptoms, 728 00:40:14,360 --> 00:40:15,920 Speaker 3: then you should be getting some treatment. 729 00:40:16,520 --> 00:40:19,959 Speaker 2: Yeah, and I do think you know what Alison brought 730 00:40:20,000 --> 00:40:22,479 Speaker 2: up that's really important for people to hear is that, 731 00:40:22,960 --> 00:40:27,200 Speaker 2: of course you have an alternative explanation than postpartum depression. 732 00:40:27,320 --> 00:40:30,480 Speaker 2: There's a million other ways that you can justify it 733 00:40:30,520 --> 00:40:34,600 Speaker 2: to yourself that like, oh, I'm probably okay and I'll 734 00:40:34,640 --> 00:40:36,840 Speaker 2: just get through this, but don't do that. You know, 735 00:40:36,880 --> 00:40:41,640 Speaker 2: if these symptoms are significantly different than baby brain and 736 00:40:41,840 --> 00:40:45,600 Speaker 2: brain fog, you know the things that make postpartum depression 737 00:40:45,640 --> 00:40:48,799 Speaker 2: postparum depression. If you look at the diagnostic criteria, it's 738 00:40:49,040 --> 00:40:52,680 Speaker 2: intense dysphoria, right, like, this is real deep sadness, not 739 00:40:52,880 --> 00:40:56,200 Speaker 2: confusion and stuff like that. Like you might see it's 740 00:40:56,480 --> 00:40:59,640 Speaker 2: an hodonia, which is that inability to feel pleasure and 741 00:40:59,680 --> 00:41:03,360 Speaker 2: things you normally take pleasure in, right, like a numbness 742 00:41:03,400 --> 00:41:07,840 Speaker 2: can be depression. Many, but not all, women with postpartum 743 00:41:07,840 --> 00:41:10,719 Speaker 2: depression actually have insomnia, which is sort of different than 744 00:41:10,760 --> 00:41:14,480 Speaker 2: what you see with you know, more typical exhaustion. I'm 745 00:41:14,600 --> 00:41:16,480 Speaker 2: up all night, like if you can't sleep when the 746 00:41:16,480 --> 00:41:20,000 Speaker 2: baby is sleeping. Those are signs of postpartum depression. And 747 00:41:20,680 --> 00:41:23,520 Speaker 2: of course many women make it through this and that's great, 748 00:41:23,640 --> 00:41:26,799 Speaker 2: but not all of them do. Like, this is a 749 00:41:26,800 --> 00:41:30,360 Speaker 2: potentially life threatening disease, so it's not something to sleep on. 750 00:41:31,200 --> 00:41:33,080 Speaker 2: And we're talking a lot about like the funn you know, 751 00:41:33,080 --> 00:41:35,440 Speaker 2: people like to tell the funny baby brain stories and whatever, 752 00:41:35,520 --> 00:41:37,920 Speaker 2: like my wife asking for the wrong instrument in the 753 00:41:37,920 --> 00:41:40,600 Speaker 2: operating room and it's like haha, you know, but postpartum 754 00:41:40,600 --> 00:41:43,920 Speaker 2: depression is what ten fifteen percent of women, at least 755 00:41:43,920 --> 00:41:46,239 Speaker 2: as far as we know, probably even higher because it 756 00:41:46,280 --> 00:41:49,920 Speaker 2: goes undiagnosed and is even potentially life threatening, right, so 757 00:41:50,200 --> 00:41:50,680 Speaker 2: be careful. 758 00:41:50,800 --> 00:41:54,560 Speaker 3: Yeah, so we talked about postpartum depression and postpartum anxiety 759 00:41:55,040 --> 00:41:59,160 Speaker 3: is a different experience but diagnosed in almost exactly the 760 00:41:59,160 --> 00:42:02,360 Speaker 3: same way. It's actually the same screening tool for anxiety 761 00:42:02,480 --> 00:42:06,239 Speaker 3: and depression. There's like sort of slightly different ways of 762 00:42:06,600 --> 00:42:09,120 Speaker 3: scoring it. And I think this gets again at the 763 00:42:09,200 --> 00:42:13,160 Speaker 3: question of like it's a little hard to separate experience 764 00:42:13,239 --> 00:42:16,840 Speaker 3: from like that there's some truth generally postpartum anxiety is 765 00:42:17,160 --> 00:42:20,799 Speaker 3: more anxiety and less depression, but there's a sort of 766 00:42:20,840 --> 00:42:23,880 Speaker 3: fine line there, and so when we think about diagnosing, 767 00:42:23,920 --> 00:42:26,640 Speaker 3: it's really about just trying to figure out to think 768 00:42:26,680 --> 00:42:28,480 Speaker 3: how things are going, and then what is the right 769 00:42:28,640 --> 00:42:31,160 Speaker 3: next treatment as opposed to like we need to label 770 00:42:31,160 --> 00:42:33,440 Speaker 3: it a particular way and. 771 00:42:33,400 --> 00:42:36,360 Speaker 4: They're treated very often with the same medication too exactly, 772 00:42:36,400 --> 00:42:36,680 Speaker 4: and they. 773 00:42:37,160 --> 00:42:40,480 Speaker 3: Yeah, okay, I want to talk about then some of 774 00:42:40,520 --> 00:42:46,160 Speaker 3: these later things, like the ADHD diagnoses, because there is 775 00:42:46,840 --> 00:42:50,440 Speaker 3: there's like the immediate postparton period when I think people 776 00:42:50,640 --> 00:42:54,080 Speaker 3: expect maybe there's some you have some postpard depression or 777 00:42:54,080 --> 00:42:58,440 Speaker 3: postpartum anxiety. You also expect to feel like slower and 778 00:42:58,480 --> 00:43:01,680 Speaker 3: so on. But then there's a much longer postpartum period 779 00:43:01,680 --> 00:43:04,399 Speaker 3: in which I think many people with small children kind 780 00:43:04,400 --> 00:43:08,160 Speaker 3: of feel like I'm still not quite, like like I'm 781 00:43:08,160 --> 00:43:10,480 Speaker 3: not back, you know, I was hoping to be back, 782 00:43:10,560 --> 00:43:11,960 Speaker 3: and I'm not back. 783 00:43:12,239 --> 00:43:13,839 Speaker 1: And this is. 784 00:43:13,800 --> 00:43:17,720 Speaker 3: Where so I pulled up in thinking about your question, 785 00:43:17,800 --> 00:43:20,400 Speaker 3: thinking about this episode, what I think is kind of 786 00:43:20,440 --> 00:43:26,440 Speaker 3: our best data about ADHD in particular. So there is 787 00:43:26,480 --> 00:43:29,719 Speaker 3: a this actually very recent paper, it's like two months old. 788 00:43:30,360 --> 00:43:33,319 Speaker 3: The most recent paper we have discussed on this is this. 789 00:43:33,280 --> 00:43:35,600 Speaker 2: The one from the Danish study. 790 00:43:35,920 --> 00:43:39,480 Speaker 3: So it's a it's a Danish study which looks at 791 00:43:39,520 --> 00:43:44,879 Speaker 3: ADHD diagnoses around pregnancy. It's very big because in these 792 00:43:44,880 --> 00:43:47,400 Speaker 3: European studies you have like everything about everybody. 793 00:43:47,520 --> 00:43:50,120 Speaker 2: So I'm so jealous of the data sets that total. 794 00:43:50,440 --> 00:43:51,000 Speaker 1: It's amazing. 795 00:43:51,000 --> 00:43:53,240 Speaker 3: So they have like three hundred and sixty thousand mothers 796 00:43:53,480 --> 00:43:57,840 Speaker 3: five hundred and twenty sorry, yeah, three hundred and sixty 797 00:43:57,840 --> 00:43:58,719 Speaker 3: three thousand. 798 00:43:59,000 --> 00:44:02,640 Speaker 1: Yes, I'm like, my. 799 00:44:02,640 --> 00:44:05,560 Speaker 3: Children are fifteen years old and eleven, so I'm still recovering. 800 00:44:05,719 --> 00:44:06,239 Speaker 1: Oh my god. 801 00:44:06,640 --> 00:44:09,399 Speaker 3: They have a very large sample size, let's just say that. 802 00:44:10,280 --> 00:44:14,120 Speaker 3: And they're looking at these ADHD rates and it's quite 803 00:44:14,120 --> 00:44:18,719 Speaker 3: interesting because they actually decrease during pregnancy and remain low 804 00:44:18,800 --> 00:44:21,719 Speaker 3: for a couple of years, and then they increase significantly 805 00:44:21,719 --> 00:44:23,160 Speaker 3: about twenty five percent. 806 00:44:22,920 --> 00:44:28,399 Speaker 1: Higher diagnoses two to five years postpartum. So we sort 807 00:44:28,440 --> 00:44:28,840 Speaker 1: of are. 808 00:44:28,760 --> 00:44:33,480 Speaker 3: Seeing this like uptick in this particular diagnosis in this 809 00:44:33,560 --> 00:44:36,480 Speaker 3: kind of like one your kids at toddler. 810 00:44:36,640 --> 00:44:37,960 Speaker 4: And I think that's there. 811 00:44:38,040 --> 00:44:41,120 Speaker 3: They're in this popular right there, And there's actually like 812 00:44:41,239 --> 00:44:43,680 Speaker 3: many different ways to interpret that. So one, I now 813 00:44:43,719 --> 00:44:45,959 Speaker 3: don't think that in this paper we can really tell 814 00:44:46,000 --> 00:44:48,680 Speaker 3: what's going on. So I think one possibility is that 815 00:44:49,360 --> 00:44:54,400 Speaker 3: this is like actually brain changes that are driving differences 816 00:44:54,440 --> 00:44:57,040 Speaker 3: in sort of the way that your brain works postpartum. 817 00:44:57,239 --> 00:45:01,080 Speaker 3: I guess second option is that the symptoms here are 818 00:45:01,200 --> 00:45:04,160 Speaker 3: close enough to the symptoms you might have of sort 819 00:45:04,200 --> 00:45:06,560 Speaker 3: of being overwhelmed and being tired and having a lot 820 00:45:07,239 --> 00:45:10,399 Speaker 3: of things going on that it would kind of you'd 821 00:45:10,400 --> 00:45:14,279 Speaker 3: get a diagnosis even though it's maybe almost situational isn't 822 00:45:14,320 --> 00:45:15,960 Speaker 3: quite the right word, but it's sort of being driven 823 00:45:16,000 --> 00:45:19,400 Speaker 3: by life experience and other possibilities people had adh this 824 00:45:19,560 --> 00:45:22,560 Speaker 3: entire time, and it is only because it's a little 825 00:45:22,600 --> 00:45:25,040 Speaker 3: exacerbated by having kids. And also this is a period 826 00:45:25,040 --> 00:45:27,480 Speaker 3: of time which maybe people are paying more attention, perhaps 827 00:45:27,480 --> 00:45:29,839 Speaker 3: maybe because they're noticing some of the symptoms in their 828 00:45:29,880 --> 00:45:32,239 Speaker 3: own kids that then they're saying, oh, that was me. 829 00:45:32,800 --> 00:45:34,680 Speaker 3: And this is a thing I hear a lot from parents, 830 00:45:34,680 --> 00:45:36,919 Speaker 3: which is very interesting, is sort of like my kid 831 00:45:37,000 --> 00:45:40,719 Speaker 3: was diagnosed with ADHD, and I realized, oh, like I 832 00:45:40,880 --> 00:45:44,160 Speaker 3: have that too, Like all of these things that I 833 00:45:44,239 --> 00:45:47,120 Speaker 3: thought were just like the way that I am are 834 00:45:47,200 --> 00:45:50,040 Speaker 3: actually like I maybe could have been getting some treatment 835 00:45:50,480 --> 00:45:53,080 Speaker 3: for this. And so I think there's like a bunch 836 00:45:53,080 --> 00:45:55,600 Speaker 3: of stuff there. I'm not sure we really have any 837 00:45:55,640 --> 00:45:57,839 Speaker 3: ability to separate those things out. 838 00:45:57,960 --> 00:45:58,840 Speaker 1: I'm not sure it matters. 839 00:45:58,880 --> 00:46:02,320 Speaker 4: But yeah, well, I guess what's what intrigues me about? 840 00:46:02,320 --> 00:46:04,279 Speaker 4: Like why do I want to know? The answer to 841 00:46:04,320 --> 00:46:07,640 Speaker 4: that is sort of I always find diagnoses of any 842 00:46:07,760 --> 00:46:11,480 Speaker 4: kind empowering. I think part of that is having anxiety 843 00:46:11,880 --> 00:46:15,239 Speaker 4: means that before the diagnosis, a huge amount of my 844 00:46:16,000 --> 00:46:20,640 Speaker 4: operating system is expending energy coming up with theories. Even 845 00:46:20,719 --> 00:46:22,960 Speaker 4: in the back of my mind, it's just ruminating on 846 00:46:23,040 --> 00:46:27,600 Speaker 4: what this is, why it is blank? And so someone 847 00:46:27,719 --> 00:46:31,080 Speaker 4: saying you are experiencing X, Y or Z, I find 848 00:46:31,160 --> 00:46:34,200 Speaker 4: deeply relaxing, even if what they're telling me I'm experiencing 849 00:46:34,320 --> 00:46:37,560 Speaker 4: is objectively stressful, because then I'm no longer wondering. I 850 00:46:37,680 --> 00:46:40,040 Speaker 4: just know and now I can do something about it. 851 00:46:40,480 --> 00:46:44,680 Speaker 4: And so for me to think of myself as having 852 00:46:44,800 --> 00:46:48,319 Speaker 4: a new brain rather than waiting to come back, has 853 00:46:48,400 --> 00:46:52,640 Speaker 4: been a very useful distinction for me, because I found 854 00:46:52,640 --> 00:46:55,839 Speaker 4: it depressing to think of my brain, which I really liked, 855 00:46:56,040 --> 00:46:59,200 Speaker 4: which was very high functioning. I was a big fan. 856 00:46:59,520 --> 00:47:00,920 Speaker 4: I can say that now because I feel like I 857 00:47:00,960 --> 00:47:02,520 Speaker 4: don't have it anymore, and I'm not like bridening. 858 00:47:02,560 --> 00:47:05,200 Speaker 1: It feels like it's not anymore. No, it's not. 859 00:47:05,400 --> 00:47:07,520 Speaker 4: It's like I'm talking about like I don't know what 860 00:47:07,560 --> 00:47:09,719 Speaker 4: my calves looked like when I was twelve, Like, you know, 861 00:47:09,760 --> 00:47:12,080 Speaker 4: it's the past part of me that doesn't exist anymore. 862 00:47:12,800 --> 00:47:15,319 Speaker 4: I loved it, and waiting for it to come back 863 00:47:15,480 --> 00:47:19,600 Speaker 4: was depressing, It was upsetting, it was frustrating, and it 864 00:47:19,960 --> 00:47:23,239 Speaker 4: wasn't going to happen. And so for me switching to 865 00:47:23,360 --> 00:47:26,680 Speaker 4: thinking this experience that I had fundamentally altered me in 866 00:47:26,800 --> 00:47:31,239 Speaker 4: literally every way. But it altered my like synapses, my 867 00:47:32,160 --> 00:47:35,160 Speaker 4: you know, everything about my cognition such that I now 868 00:47:35,280 --> 00:47:38,200 Speaker 4: have a new operating system. I have to learn how 869 00:47:38,239 --> 00:47:40,759 Speaker 4: it works and learn how to best support it and 870 00:47:41,680 --> 00:47:43,759 Speaker 4: find out how to use it, Like I learned how 871 00:47:43,800 --> 00:47:47,120 Speaker 4: to use my old brain and use this one for 872 00:47:47,400 --> 00:47:51,040 Speaker 4: whatever I need it for now. And I found that 873 00:47:51,080 --> 00:47:53,520 Speaker 4: to be really useful. And that could just be me, 874 00:47:53,840 --> 00:47:56,080 Speaker 4: or it could be it could be other people as well. 875 00:47:56,560 --> 00:48:00,000 Speaker 3: No, I think it's I think it's actually very interesting 876 00:48:00,120 --> 00:48:04,200 Speaker 3: and valuable frame for people, in part because so many 877 00:48:04,239 --> 00:48:09,960 Speaker 3: of these things are are really like diagnoses of like 878 00:48:10,080 --> 00:48:12,880 Speaker 3: experience and how are things working for you? And so 879 00:48:13,080 --> 00:48:16,839 Speaker 3: to say like, you know, well you didn't have ADHD before, 880 00:48:16,880 --> 00:48:19,680 Speaker 3: so let's not look for that as a solution may 881 00:48:19,680 --> 00:48:21,759 Speaker 3: be unhelpful as opposed to being like, right now, we 882 00:48:21,760 --> 00:48:24,120 Speaker 3: should try to figure out, like what's going on and 883 00:48:24,200 --> 00:48:27,680 Speaker 3: how can we best support your functioning as a person, 884 00:48:27,960 --> 00:48:31,239 Speaker 3: whether that's something that was true before or not. And 885 00:48:31,320 --> 00:48:33,560 Speaker 3: it may be for some people to say the like, well, 886 00:48:33,640 --> 00:48:36,960 Speaker 3: now you know my brain, the operating system is different 887 00:48:37,000 --> 00:48:37,560 Speaker 3: and we need. 888 00:48:37,480 --> 00:48:40,120 Speaker 1: Like a different set of you know, software tools. 889 00:48:40,440 --> 00:48:42,359 Speaker 4: I also think we live in a time where we're 890 00:48:42,400 --> 00:48:46,359 Speaker 4: really lucky we don't we don't technically have to white 891 00:48:46,400 --> 00:48:49,600 Speaker 4: knuckle a lot of the things that we tolerate. So 892 00:48:49,640 --> 00:48:52,919 Speaker 4: the idea that I can talk to my psychiatrist and say, Okay, 893 00:48:52,920 --> 00:48:56,520 Speaker 4: we're gonna address my anxiety because that's too much. I'm 894 00:48:56,600 --> 00:48:59,120 Speaker 4: fed up. I can't live like this. It's exhausting. And 895 00:48:59,160 --> 00:49:01,920 Speaker 4: then once that's been addressed, there are all these other 896 00:49:02,000 --> 00:49:05,200 Speaker 4: behaviors and these other executive functioning issues that are revealed 897 00:49:05,480 --> 00:49:07,359 Speaker 4: not to be part of the anxiety but something else. 898 00:49:07,440 --> 00:49:09,440 Speaker 4: The fact that I don't have to live with those 899 00:49:09,560 --> 00:49:13,520 Speaker 4: and tolerate those and spend the energy operating around those 900 00:49:14,120 --> 00:49:17,040 Speaker 4: is such a privilege of you know, I talk, I 901 00:49:17,480 --> 00:49:19,279 Speaker 4: talking a lot of shit about being a human in 902 00:49:19,280 --> 00:49:22,239 Speaker 4: this stage of evolution, but we're very smart because those 903 00:49:22,280 --> 00:49:25,000 Speaker 4: big brains, and we've developed medication that means I don't 904 00:49:25,040 --> 00:49:27,600 Speaker 4: have to just figure out how to live with these 905 00:49:27,640 --> 00:49:31,239 Speaker 4: things if I don't want to. There is help available 906 00:49:31,239 --> 00:49:34,000 Speaker 4: to me, which is so incredible. And I wish I 907 00:49:34,040 --> 00:49:36,920 Speaker 4: had availed myself a bit sooner. And I can't, like 908 00:49:38,200 --> 00:49:41,600 Speaker 4: I don't know, biohack my way through it or just 909 00:49:41,960 --> 00:49:46,640 Speaker 4: you know, I don't know what and get rid of 910 00:49:46,760 --> 00:49:51,400 Speaker 4: you tried any time I have injected them into my 911 00:49:51,440 --> 00:49:52,560 Speaker 4: brain and it didn't work. 912 00:49:53,040 --> 00:49:54,040 Speaker 1: I'm doing it wrong. 913 00:49:55,520 --> 00:49:59,000 Speaker 2: As you're talking about you know what changes are long term, 914 00:49:59,120 --> 00:50:03,080 Speaker 2: and yeah, of course it's really hard to measure, but 915 00:50:03,400 --> 00:50:06,399 Speaker 2: I will just say, like number one, our brains are 916 00:50:06,560 --> 00:50:09,160 Speaker 2: changing all the time, right, Like we can learn, we 917 00:50:09,200 --> 00:50:11,359 Speaker 2: can go to therapy. You know, It's always been sort 918 00:50:11,400 --> 00:50:14,400 Speaker 2: of an amazing thing to me that talk therapy works, 919 00:50:14,640 --> 00:50:20,719 Speaker 2: and it's just somehow like if you really make it abstract, 920 00:50:20,760 --> 00:50:23,719 Speaker 2: like someone is speaking words into your ear and it's 921 00:50:23,800 --> 00:50:27,800 Speaker 2: reprogramming slowly your brain until it's connected in a slightly 922 00:50:27,800 --> 00:50:29,480 Speaker 2: different way that makes you feel better. I always think 923 00:50:29,480 --> 00:50:33,720 Speaker 2: that's amazing. So these changes are always happening. I can't 924 00:50:34,040 --> 00:50:37,359 Speaker 2: imagine a more significant physiologic event than pregnancy. I think 925 00:50:37,360 --> 00:50:40,080 Speaker 2: I've said this multiple times right now, you know, I 926 00:50:40,080 --> 00:50:43,200 Speaker 2: don't think anyone would take a person who like, like 927 00:50:43,239 --> 00:50:46,800 Speaker 2: went through chemotherapy and came out the other side cancer 928 00:50:46,840 --> 00:50:49,080 Speaker 2: free and would be like like, okay, and so you're 929 00:50:49,080 --> 00:50:51,200 Speaker 2: back to normal now, right like everything, you're the same 930 00:50:51,200 --> 00:50:53,440 Speaker 2: person you were before you did chemo, right, Like that 931 00:50:53,440 --> 00:50:56,840 Speaker 2: would be almost considered inappropriate, Like how are you not 932 00:50:57,320 --> 00:51:02,120 Speaker 2: respecting the struggle I just went through? And pregnancy is 933 00:51:02,600 --> 00:51:06,240 Speaker 2: much like this, Like I definitely think your brain is different, 934 00:51:06,280 --> 00:51:09,719 Speaker 2: It's different forever. That's not all bad. In fact, you know, 935 00:51:09,760 --> 00:51:12,520 Speaker 2: Emily pointed out some of the brain aging data that 936 00:51:12,560 --> 00:51:15,280 Speaker 2: looks at like, you know, whether you when you're sixty, 937 00:51:15,320 --> 00:51:17,000 Speaker 2: do you have a brain of a sixty one year 938 00:51:17,000 --> 00:51:18,439 Speaker 2: old or a fifty nine year old or a fifty 939 00:51:18,440 --> 00:51:20,839 Speaker 2: five year old. And one of the predictors of how 940 00:51:20,880 --> 00:51:23,600 Speaker 2: young your brain is in older age is how many 941 00:51:23,680 --> 00:51:25,720 Speaker 2: children you've had with I was going to ask. 942 00:51:25,640 --> 00:51:31,279 Speaker 4: Is it cumulative these effects over several children or yeah. 943 00:51:30,840 --> 00:51:36,480 Speaker 2: So the study that I was looking at, there's two here. 944 00:51:36,520 --> 00:51:39,560 Speaker 2: One is from the UK Biobank, which is which is 945 00:51:39,600 --> 00:51:43,879 Speaker 2: a big study hundreds of thousands of people over time, 946 00:51:43,880 --> 00:51:48,880 Speaker 2: which does show that multiparis women, women who had you know, 947 00:51:48,920 --> 00:51:53,040 Speaker 2: more than one child had younger brains than women who 948 00:51:53,080 --> 00:51:55,640 Speaker 2: had one child, which had a younger brain than women 949 00:51:55,719 --> 00:51:58,920 Speaker 2: who never had children. There's also a smaller study out 950 00:51:58,920 --> 00:52:01,880 Speaker 2: of Rotterdam that basically showed a dose response where the 951 00:52:01,880 --> 00:52:04,799 Speaker 2: more kids you had, the more great matter volume you 952 00:52:04,840 --> 00:52:07,399 Speaker 2: had in older age. So yes, so it's the same 953 00:52:07,440 --> 00:52:10,480 Speaker 2: gray matter that like shrinks during pregnancy, you end up 954 00:52:10,480 --> 00:52:13,200 Speaker 2: with more in older age. I did dig a little 955 00:52:13,200 --> 00:52:15,879 Speaker 2: bit deeply and found there there was one study that, look, 956 00:52:15,920 --> 00:52:18,960 Speaker 2: what's the term, Emily, for women who've had like a 957 00:52:18,960 --> 00:52:22,640 Speaker 2: lot a lot of babies, Like, uh, super multi paris 958 00:52:22,680 --> 00:52:23,160 Speaker 2: what's it called? 959 00:52:23,320 --> 00:52:24,760 Speaker 1: Yes, Like, yes, it's super? 960 00:52:25,280 --> 00:52:25,880 Speaker 2: Is that what it is? 961 00:52:25,960 --> 00:52:26,560 Speaker 1: Something like that? 962 00:52:26,640 --> 00:52:29,399 Speaker 2: Yes, I'm honestly I forget. In any case, there does 963 00:52:29,440 --> 00:52:32,000 Speaker 2: seem to maybe it falls off like after you know, 964 00:52:32,080 --> 00:52:36,040 Speaker 2: seven eight kids. But but the question is, I don't 965 00:52:36,040 --> 00:52:39,480 Speaker 2: think it's the pregnancy that makes your brain better. I 966 00:52:39,520 --> 00:52:43,520 Speaker 2: think it's the children to some extent, like children represent 967 00:52:43,640 --> 00:52:47,200 Speaker 2: this whole new source of novelty in your life. Like 968 00:52:47,280 --> 00:52:52,640 Speaker 2: the thing that counterpoint, I'm about to say something very 969 00:52:52,640 --> 00:52:56,400 Speaker 2: sweet about my children who may listen to this someday. 970 00:52:56,560 --> 00:52:59,399 Speaker 2: One of the wonderful things about having children is that 971 00:53:00,080 --> 00:53:02,680 Speaker 2: the only way you get to experience something you love 972 00:53:03,239 --> 00:53:07,680 Speaker 2: for the first time again. So like I got to 973 00:53:07,760 --> 00:53:12,400 Speaker 2: watch The Fellowship of the Ring with my oldest daughter, 974 00:53:12,520 --> 00:53:14,520 Speaker 2: and I got to go through the whole thing again, 975 00:53:14,560 --> 00:53:17,040 Speaker 2: even though I'd seen it, you know, thirty thirty times 976 00:53:17,920 --> 00:53:20,759 Speaker 2: by the time. And I think that's good for your brain. 977 00:53:20,840 --> 00:53:22,799 Speaker 2: I think it. I think it keeps you. I think 978 00:53:22,800 --> 00:53:24,759 Speaker 2: they keep you young. All right, Emily, I'm wrong. 979 00:53:24,800 --> 00:53:30,760 Speaker 3: Why you know, just in rats having babies improves their 980 00:53:31,080 --> 00:53:35,319 Speaker 3: maze performance and long term spatial learning and memory and work. 981 00:53:35,360 --> 00:53:37,640 Speaker 3: And I don't think it's because they're parenting at a 982 00:53:37,680 --> 00:53:40,719 Speaker 3: high level. I mean there's no fellowship. They didnt show 983 00:53:40,719 --> 00:53:42,920 Speaker 3: them the fellowship with a ring or whatever. They just 984 00:53:42,960 --> 00:53:46,960 Speaker 3: probably have the babies in a way because it's fucking rats. 985 00:53:47,000 --> 00:53:50,840 Speaker 4: This way pure anetdata. But I actually do resonate with 986 00:53:50,880 --> 00:53:56,040 Speaker 4: that idea of spatial Like I think I recognize faces 987 00:53:56,080 --> 00:53:59,200 Speaker 4: and places better now than I did. Oh that's cir 988 00:53:59,480 --> 00:54:01,800 Speaker 4: my memory of like have I been to this restaurant before? 989 00:54:01,920 --> 00:54:03,840 Speaker 4: Have I met this person? Have I stayed at this hotel? 990 00:54:03,880 --> 00:54:07,080 Speaker 4: It was really bad before and now it's decent. So 991 00:54:07,280 --> 00:54:07,920 Speaker 4: that's interesting. 992 00:54:08,160 --> 00:54:11,520 Speaker 2: If it helps recognizing faces. I would love to be pregnant, 993 00:54:11,600 --> 00:54:12,160 Speaker 2: that is mine. 994 00:54:12,560 --> 00:54:16,520 Speaker 3: I cannot recognize faces, and I have been pregnant twice 995 00:54:16,560 --> 00:54:17,360 Speaker 3: and it did not approve. 996 00:54:18,160 --> 00:54:20,800 Speaker 4: You have like a true face blindness. 997 00:54:21,080 --> 00:54:23,680 Speaker 3: Not a true face blindness, but I just can't. I like, 998 00:54:24,320 --> 00:54:26,279 Speaker 3: name face barely to who are you? 999 00:54:27,400 --> 00:54:30,840 Speaker 4: Who am I? I don't know. 1000 00:54:30,440 --> 00:54:32,920 Speaker 1: It'sciding your name is on the you know podcast thing? 1001 00:54:33,040 --> 00:54:36,960 Speaker 3: Yeah exactly, Okay, I want to before we before we 1002 00:54:37,080 --> 00:54:41,880 Speaker 3: end and get to question I want to talk about. 1003 00:54:42,080 --> 00:54:43,799 Speaker 3: I want to sort of step back one thing, because 1004 00:54:44,000 --> 00:54:46,919 Speaker 3: we talked a lot about like brain changes that are real, 1005 00:54:47,160 --> 00:54:49,239 Speaker 3: and you know the fact that maybe some of this 1006 00:54:49,320 --> 00:54:52,000 Speaker 3: is inevitable and so on, but there actually are some 1007 00:54:52,600 --> 00:54:57,480 Speaker 3: like biological changes during pregnancy that if you are feeling 1008 00:54:58,760 --> 00:55:01,799 Speaker 3: very tired or just very off, it actually is a 1009 00:55:01,880 --> 00:55:06,120 Speaker 3: worthwhile to get some blood work because, for example, a 1010 00:55:06,239 --> 00:55:08,520 Speaker 3: large share of women who have been pregnant women of 1011 00:55:08,600 --> 00:55:11,799 Speaker 3: child bearing age are anemic, and which means your iron 1012 00:55:11,880 --> 00:55:14,680 Speaker 3: is too low, and anemia can cause a lot of 1013 00:55:14,680 --> 00:55:17,040 Speaker 3: the kinds of symptoms we're talking about in particular, like 1014 00:55:17,080 --> 00:55:20,000 Speaker 3: brain fog and fatigue and just like a feeling of 1015 00:55:20,040 --> 00:55:24,200 Speaker 3: being quite exhausted. And so I would sort of balance 1016 00:55:24,239 --> 00:55:26,520 Speaker 3: a little bit as like your brain is new and 1017 00:55:26,680 --> 00:55:28,480 Speaker 3: you got a learn to live with it, and also 1018 00:55:28,719 --> 00:55:32,080 Speaker 3: like go get your thyroid and your anemia checked, because 1019 00:55:32,600 --> 00:55:34,719 Speaker 3: if it turns out that the answer to some of 1020 00:55:34,719 --> 00:55:37,880 Speaker 3: this is like you need to be taking an iron pill, 1021 00:55:38,000 --> 00:55:40,279 Speaker 3: like that would be good too no and too bad 1022 00:55:40,360 --> 00:55:41,520 Speaker 3: to miss. 1023 00:55:41,560 --> 00:55:44,640 Speaker 2: Right, Yeah, go for the easy fis. Yeah, totally. You know, 1024 00:55:44,760 --> 00:55:48,720 Speaker 2: other sort of treatments for we're going to put postpartum 1025 00:55:48,760 --> 00:55:51,400 Speaker 2: depression aside, obviously postpartum depression you want to get your 1026 00:55:51,400 --> 00:55:54,799 Speaker 2: treatments from a doctor and things like that. But for 1027 00:55:54,920 --> 00:55:58,440 Speaker 2: just the regular baby brain fog and stuff like that, 1028 00:55:58,800 --> 00:56:04,239 Speaker 2: obviously sleep is going to come up number one rustrating. 1029 00:56:05,760 --> 00:56:08,080 Speaker 2: Just you should just say more. I don't know why 1030 00:56:08,120 --> 00:56:08,799 Speaker 2: you guys. 1031 00:56:10,360 --> 00:56:11,520 Speaker 4: Why didn't I think of that? 1032 00:56:14,520 --> 00:56:18,399 Speaker 2: So, actually, this is a good question. You both had 1033 00:56:18,880 --> 00:56:22,440 Speaker 2: a partner after the baby was born. How can partners 1034 00:56:22,480 --> 00:56:27,480 Speaker 2: support the new mom during this period so that she 1035 00:56:27,560 --> 00:56:30,560 Speaker 2: can get the much needed rest? Is it bringing cups 1036 00:56:30,560 --> 00:56:32,640 Speaker 2: of water without being. 1037 00:56:32,560 --> 00:56:35,040 Speaker 4: Asked in that doorway as long as I need you 1038 00:56:35,080 --> 00:56:37,480 Speaker 4: to before I can summon the words that I need. 1039 00:56:37,680 --> 00:56:39,640 Speaker 2: I think, then just bring a glass of water. 1040 00:56:39,640 --> 00:56:42,080 Speaker 1: You don't need, don't don't ask, just bring the water. 1041 00:56:43,000 --> 00:56:47,160 Speaker 4: I feel like, honestly, it's having respect for what's happening. 1042 00:56:47,400 --> 00:56:50,600 Speaker 4: It feels like there's just a knowledge gap. I don't 1043 00:56:50,640 --> 00:56:53,799 Speaker 4: think it's just among men. I think most women who 1044 00:56:53,880 --> 00:56:56,319 Speaker 4: go through this process don't understand what's happening to their 1045 00:56:56,360 --> 00:57:00,759 Speaker 4: bodies either. But I think you know that amount of 1046 00:57:00,800 --> 00:57:07,120 Speaker 4: hormonal shift is worthy of respect and awareness and acknowledgment 1047 00:57:07,360 --> 00:57:12,200 Speaker 4: and understanding that for I don't know what the biggest 1048 00:57:12,239 --> 00:57:16,160 Speaker 4: hormonal shift in a man is. I'm guessing it's around arousal, 1049 00:57:16,280 --> 00:57:19,040 Speaker 4: probably somehow, and we just. 1050 00:57:19,000 --> 00:57:24,400 Speaker 2: Don't have anything comparable in any way. But even doing so, 1051 00:57:24,480 --> 00:57:26,920 Speaker 2: the facts and a box spar it's for weightlifting is 1052 00:57:26,960 --> 00:57:27,400 Speaker 2: not the same. 1053 00:57:27,520 --> 00:57:30,200 Speaker 4: Yeah, maybe I mean, but even that, I just feel 1054 00:57:30,200 --> 00:57:34,320 Speaker 4: like understanding that it's both things can be true at 1055 00:57:34,360 --> 00:57:37,120 Speaker 4: the same time. The person you're talking to is your spouse, 1056 00:57:37,320 --> 00:57:40,600 Speaker 4: and you should take what they are saying and experiencing seriously. 1057 00:57:40,920 --> 00:57:45,240 Speaker 4: And if they wrote a document and had it notarized 1058 00:57:45,280 --> 00:57:47,800 Speaker 4: about their opinions and their feelings in a given moment, 1059 00:57:48,040 --> 00:57:52,720 Speaker 4: it may not feel correct anymore a week later, and 1060 00:57:52,800 --> 00:57:55,520 Speaker 4: that is okay, And it doesn't mean you should ignore 1061 00:57:55,560 --> 00:57:58,000 Speaker 4: what they say. You're in a liminal space where it 1062 00:57:58,080 --> 00:58:00,439 Speaker 4: is and it isn't your partner, and what they say 1063 00:58:00,600 --> 00:58:03,680 Speaker 4: is and isn't true, and just deal with it because 1064 00:58:03,680 --> 00:58:05,160 Speaker 4: you're going to deal with it for such a brief 1065 00:58:05,200 --> 00:58:07,760 Speaker 4: period compared to the amount of time they spent in 1066 00:58:07,760 --> 00:58:10,560 Speaker 4: that liminal space themselves. That's kind of what I might say, Emily, 1067 00:58:10,640 --> 00:58:11,560 Speaker 4: what do you what do you think? 1068 00:58:11,600 --> 00:58:13,160 Speaker 1: That's such amazing advice. 1069 00:58:13,200 --> 00:58:14,760 Speaker 3: The main thing my husband did when he's made a 1070 00:58:14,760 --> 00:58:17,000 Speaker 3: spreadsheet that we could keep track of how many minutes 1071 00:58:17,600 --> 00:58:20,040 Speaker 3: my daughter was eating at different times and how many 1072 00:58:20,160 --> 00:58:22,320 Speaker 3: frequency of pooping, which I actually wouldn't. 1073 00:58:22,960 --> 00:58:25,360 Speaker 4: I remember you saying that on the podcast. There was 1074 00:58:25,400 --> 00:58:28,000 Speaker 4: a there's an app for that now called baby Trasher, 1075 00:58:28,040 --> 00:58:30,800 Speaker 4: which I will shock you by telling you. I also 1076 00:58:31,000 --> 00:58:35,080 Speaker 4: use just to feel some control over completely uncontrollable. 1077 00:58:35,160 --> 00:58:37,880 Speaker 2: I feel like spreadsheets are Emily's love language. 1078 00:58:38,040 --> 00:58:40,280 Speaker 1: Totally no, but I just don't think that's for everybody. 1079 00:58:40,640 --> 00:58:42,520 Speaker 1: Not sure that's well I think. 1080 00:58:42,840 --> 00:58:46,720 Speaker 3: But I will say my husband was constantly making sure 1081 00:58:46,720 --> 00:58:49,600 Speaker 3: that I was eating like his main His his love 1082 00:58:49,680 --> 00:58:52,640 Speaker 3: language was like like there is always. 1083 00:58:52,320 --> 00:58:56,320 Speaker 1: Water and like fruit next to the like breastfeeding chair. 1084 00:58:57,000 --> 00:58:59,000 Speaker 4: So nice, it's great, it's so nice. 1085 00:59:00,040 --> 00:59:02,160 Speaker 3: We haven't really discussed endurance sports yet, and so I 1086 00:59:02,280 --> 00:59:06,640 Speaker 3: just wanted to pop in here and say that that 1087 00:59:07,120 --> 00:59:11,640 Speaker 3: your elevated blood volume retains for about a year postpartum, 1088 00:59:11,680 --> 00:59:14,600 Speaker 3: and so there is some people think that that's why 1089 00:59:14,640 --> 00:59:18,160 Speaker 3: some people perform quite well at their sporting events in 1090 00:59:18,200 --> 00:59:22,200 Speaker 3: the first year postpartum, because of the potentially higher bloodvolume. 1091 00:59:22,640 --> 00:59:25,760 Speaker 3: And I represent the group that thanks lol sporting events 1092 00:59:25,800 --> 00:59:27,160 Speaker 3: in the first year post. 1093 00:59:27,680 --> 00:59:29,880 Speaker 1: Yeah, it's not like a Yes, there are some other 1094 00:59:29,920 --> 00:59:30,520 Speaker 1: things that make. 1095 00:59:30,400 --> 00:59:33,480 Speaker 4: You slower, moving not in a walking pace from one 1096 00:59:33,520 --> 00:59:34,280 Speaker 4: room to another. 1097 00:59:36,840 --> 00:59:40,760 Speaker 3: All right, Perry, smash your pass on the pregnancy brain 1098 00:59:40,840 --> 00:59:41,920 Speaker 3: and even know what this means. 1099 00:59:42,360 --> 00:59:44,360 Speaker 2: I think it's important for me to weigh in here though. 1100 00:59:44,800 --> 00:59:45,800 Speaker 1: Yeah, totally. 1101 00:59:45,960 --> 00:59:48,760 Speaker 4: As always, I'm a pass. 1102 00:59:48,880 --> 00:59:51,360 Speaker 2: I you know, let's let's get over. I agree with Alison. 1103 00:59:51,880 --> 00:59:56,000 Speaker 2: I don't know techno Bros. Fixed pregnancy. Emily, how about 1104 00:59:56,000 --> 00:59:57,040 Speaker 2: you smash pass. 1105 00:59:57,600 --> 01:00:00,440 Speaker 3: I'm a smash because I'm my kid's tiny pieces of 1106 01:00:00,480 --> 01:00:02,720 Speaker 3: my kids are around in my brain and that's and 1107 01:00:02,760 --> 01:00:05,840 Speaker 3: that's so great, Allison. 1108 01:00:06,440 --> 01:00:09,040 Speaker 4: I guess I'm I'm a reluctant smash for the same 1109 01:00:09,080 --> 01:00:13,320 Speaker 4: reason because now I'd be like passing on my child existing, 1110 01:00:13,440 --> 01:00:15,840 Speaker 4: and that feels insane because he's made the world so 1111 01:00:15,880 --> 01:00:19,600 Speaker 4: much better. But I have a lot of notes for 1112 01:00:19,720 --> 01:00:21,680 Speaker 4: the way it all goes down, and I don't know 1113 01:00:21,680 --> 01:00:24,360 Speaker 4: who to talk to about this, but it's we have 1114 01:00:24,440 --> 01:00:26,840 Speaker 4: a lot of improve room for improvement. 1115 01:00:26,880 --> 01:00:31,400 Speaker 3: I would say that is it for pregnancy brain. Allison's 1116 01:00:31,440 --> 01:00:33,960 Speaker 3: Mailbag question of the Week after the Break. 1117 01:00:39,200 --> 01:00:42,280 Speaker 4: Emily, I've come to realize that you are not just 1118 01:00:42,560 --> 01:00:48,280 Speaker 4: a casual runner. You are. You are runner like ken 1119 01:00:48,400 --> 01:00:51,960 Speaker 4: Is Beach. You are runner, and thus I have a 1120 01:00:52,040 --> 01:00:54,880 Speaker 4: question for you. I have to start doing cardio because 1121 01:00:54,880 --> 01:00:56,800 Speaker 4: I'm doing a movie that's going to require me to 1122 01:00:57,920 --> 01:01:01,560 Speaker 4: be cardiovascularly alive in a way that I'm not on 1123 01:01:01,600 --> 01:01:03,040 Speaker 4: a day to day basis. I have to pretend to 1124 01:01:03,040 --> 01:01:04,440 Speaker 4: be a type of person I'm not, which is my 1125 01:01:04,480 --> 01:01:08,880 Speaker 4: whole job. And I don't have extra time though to 1126 01:01:09,120 --> 01:01:12,360 Speaker 4: do this cardio. So I am wondering what is the 1127 01:01:12,360 --> 01:01:14,560 Speaker 4: best bang for my buck if I don't have a 1128 01:01:14,560 --> 01:01:17,320 Speaker 4: lot of time. But I just it's not necessarily about 1129 01:01:17,360 --> 01:01:20,280 Speaker 4: weight loss or anything. It's just about getting my ability 1130 01:01:20,320 --> 01:01:25,080 Speaker 4: to deliver lines while hyperventilating to be like, what's the 1131 01:01:25,920 --> 01:01:28,040 Speaker 4: what did Taylor Swift do before the airstore so she 1132 01:01:28,080 --> 01:01:30,919 Speaker 4: could sing and run one hundred miles in a day? 1133 01:01:31,080 --> 01:01:32,040 Speaker 4: You know what do I do? 1134 01:01:32,680 --> 01:01:33,000 Speaker 1: Okay? 1135 01:01:33,000 --> 01:01:35,000 Speaker 3: So, first of all, what Taylor Swift did was she 1136 01:01:35,160 --> 01:01:39,080 Speaker 3: ran every day on the treadmill doing the entire set 1137 01:01:39,240 --> 01:01:41,240 Speaker 3: for three hours. So she would run like three hours 1138 01:01:41,240 --> 01:01:43,040 Speaker 3: a day on the treadmill doing the entire set. It 1139 01:01:43,080 --> 01:01:44,880 Speaker 3: sounds to me like you don't have time for that. 1140 01:01:45,280 --> 01:01:48,400 Speaker 4: I definitely don't, although I could because I'm such a 1141 01:01:48,400 --> 01:01:50,360 Speaker 4: swift ye, I could do the whole set. 1142 01:01:52,440 --> 01:01:53,520 Speaker 1: But you don't want to run? 1143 01:01:53,800 --> 01:01:56,360 Speaker 4: Is that I can't? My knees are just it's like 1144 01:01:56,480 --> 01:01:59,080 Speaker 4: someone read the instructions wrong when they put my knees together. 1145 01:01:59,360 --> 01:02:00,920 Speaker 4: They don't, okay, work properly. 1146 01:02:01,040 --> 01:02:04,760 Speaker 3: So you're pretty I think this is not a very 1147 01:02:04,760 --> 01:02:07,520 Speaker 3: hard question to answer because what you really want to 1148 01:02:07,560 --> 01:02:11,920 Speaker 3: be doing is spending some time in like a high 1149 01:02:12,080 --> 01:02:17,480 Speaker 3: heart rate zone like zone four five and out of 1150 01:02:17,520 --> 01:02:21,479 Speaker 3: what what is that? There's five zones? It doesn't matter. 1151 01:02:21,520 --> 01:02:23,800 Speaker 1: You want to be raising your heart rate that's maxed. 1152 01:02:23,560 --> 01:02:25,520 Speaker 4: Out like five out of five. I don't know much, 1153 01:02:25,560 --> 01:02:28,000 Speaker 4: but that's one hundred percent. It's a hundred Yeah, don't 1154 01:02:28,000 --> 01:02:29,440 Speaker 4: get okay, yeah, okay. 1155 01:02:29,600 --> 01:02:31,800 Speaker 3: You want to be working hard, like you want to 1156 01:02:31,800 --> 01:02:35,000 Speaker 3: think about getting some time in a cardio activity where 1157 01:02:35,040 --> 01:02:38,520 Speaker 3: you couldn't talk, or like if somebody came to sort 1158 01:02:38,520 --> 01:02:41,160 Speaker 3: of in your husband's game and started chatting, you would 1159 01:02:41,200 --> 01:02:44,320 Speaker 3: just like not be able to chat back to him. 1160 01:02:44,760 --> 01:02:46,800 Speaker 3: But it can be like intervals of that. You don't 1161 01:02:46,800 --> 01:02:48,480 Speaker 3: have to do that for like a long period of time. 1162 01:02:48,800 --> 01:02:51,000 Speaker 3: Your best bet is going to be a bike. You 1163 01:02:51,040 --> 01:02:54,840 Speaker 3: should get some kind of very fun exercise bike situation. 1164 01:02:55,600 --> 01:02:59,800 Speaker 3: You can get these bikes. People, the endurance guys really 1165 01:02:59,880 --> 01:03:03,120 Speaker 3: like these swift bikes where you can like race other 1166 01:03:04,200 --> 01:03:08,080 Speaker 3: crazy people in like inside a swift race, and it 1167 01:03:08,200 --> 01:03:10,360 Speaker 3: like adjusts the thing so you can be like in 1168 01:03:10,440 --> 01:03:12,640 Speaker 3: the Tour de France with the other guys, and if 1169 01:03:12,640 --> 01:03:16,360 Speaker 3: you win, then you like win extra accessories for your bike, 1170 01:03:17,680 --> 01:03:21,760 Speaker 3: your fake swift bike in the in the game, it's 1171 01:03:20,960 --> 01:03:25,800 Speaker 3: a it's a video game biking app. But at any rate, 1172 01:03:25,840 --> 01:03:30,520 Speaker 3: you want some kind of interval based biking on like 1173 01:03:30,560 --> 01:03:33,640 Speaker 3: a stationary bike where you are working quite hard to 1174 01:03:33,680 --> 01:03:35,320 Speaker 3: the point where you couldn't talk. 1175 01:03:35,680 --> 01:03:38,000 Speaker 4: Can I ask a very ignorant question. It feels like 1176 01:03:38,040 --> 01:03:40,440 Speaker 4: there's a lot of types of indoor bikes. There's the 1177 01:03:40,480 --> 01:03:42,560 Speaker 4: soul cycle one that I did when everyone was doing 1178 01:03:42,600 --> 01:03:46,720 Speaker 4: a soul cycle and I obediently also did it. So 1179 01:03:46,760 --> 01:03:49,439 Speaker 4: there's that one where you're like leaning forward. There's one 1180 01:03:49,560 --> 01:03:52,400 Speaker 4: that's also in gym's where it seems to be more 1181 01:03:52,440 --> 01:03:57,480 Speaker 4: of a an sort of seated upright situation. And then 1182 01:03:57,520 --> 01:04:00,439 Speaker 4: there's the third one, which is there's a big fan 1183 01:04:00,560 --> 01:04:03,400 Speaker 4: in the front and your arms are part of it, 1184 01:04:03,760 --> 01:04:06,520 Speaker 4: which is the bike you picture when you say biking. 1185 01:04:07,120 --> 01:04:10,200 Speaker 3: Just any of these is fine. Just a regular bike 1186 01:04:10,320 --> 01:04:12,880 Speaker 3: is fine. You just need to go set the resistance 1187 01:04:12,880 --> 01:04:14,160 Speaker 3: hard enough that your heart rate goes up. 1188 01:04:14,200 --> 01:04:14,520 Speaker 5: That's all. 1189 01:04:14,680 --> 01:04:15,840 Speaker 4: Okay, okay, what do. 1190 01:04:15,840 --> 01:04:16,680 Speaker 2: You think about swimming? 1191 01:04:17,040 --> 01:04:21,520 Speaker 3: M I generally do not think swimming is going to 1192 01:04:21,600 --> 01:04:23,560 Speaker 3: raise her heart rate enough. 1193 01:04:24,240 --> 01:04:27,400 Speaker 1: And it takes a lot more time because you have to. 1194 01:04:27,360 --> 01:04:28,720 Speaker 3: Like go to the gym and you have to put 1195 01:04:28,720 --> 01:04:30,280 Speaker 3: your swim soon on, you have to get into the water, 1196 01:04:30,320 --> 01:04:32,280 Speaker 3: and the gym pool is not available. The bike is 1197 01:04:32,320 --> 01:04:35,240 Speaker 3: like stationary. Bike is like the easiest. You tell me 1198 01:04:35,280 --> 01:04:38,120 Speaker 3: you have thirty minutes. You do like five minutes of 1199 01:04:38,160 --> 01:04:42,080 Speaker 3: warm up, three minute intervals with a one minute rest 1200 01:04:42,400 --> 01:04:44,000 Speaker 3: until you feel like you're going to die, and then 1201 01:04:44,000 --> 01:04:44,720 Speaker 3: you get off the bike. 1202 01:04:45,400 --> 01:04:47,200 Speaker 4: That sounds yeah, I love it. That sounds like it 1203 01:04:47,240 --> 01:04:47,960 Speaker 4: sounds terrible. 1204 01:04:48,160 --> 01:04:49,760 Speaker 1: That's what you want. That's what I know. 1205 01:04:50,000 --> 01:04:52,640 Speaker 4: I know again, though, if any tech bro can come 1206 01:04:52,720 --> 01:04:54,280 Speaker 4: up with a version of this where I don't actually 1207 01:04:54,280 --> 01:04:57,240 Speaker 4: have to work very hard and can be physically comfortable 1208 01:04:57,320 --> 01:05:01,120 Speaker 4: while something is doing my cardio interested. 1209 01:05:02,840 --> 01:05:08,280 Speaker 1: That's what the peptizer for. Thank you for being here 1210 01:05:08,320 --> 01:05:09,600 Speaker 1: else and we really appreciate it. 1211 01:05:09,640 --> 01:05:12,320 Speaker 4: Thank you for allowing me to be here and acquiescing 1212 01:05:13,320 --> 01:05:15,560 Speaker 4: when I refused to take no for an answer. 1213 01:05:15,880 --> 01:05:18,040 Speaker 2: You have carte blanche for any future topics. 1214 01:05:18,280 --> 01:05:20,680 Speaker 4: Do not say that I've talked so much in this 1215 01:05:20,800 --> 01:05:24,720 Speaker 4: episode because I'm so excited. It's embarrassing. But okay, fine, 1216 01:05:24,720 --> 01:05:26,120 Speaker 4: I'll come back every week. 1217 01:05:26,320 --> 01:05:26,640 Speaker 1: Great. 1218 01:05:27,920 --> 01:05:30,080 Speaker 3: Stick with us next week when we'll ask what's the 1219 01:05:30,160 --> 01:05:41,160 Speaker 3: deal with alcohol? Wellness Actually is produced in association with iHeartMedia. 1220 01:05:41,720 --> 01:05:43,680 Speaker 1: Our senior producer is Tamar Abshi. 1221 01:05:44,080 --> 01:05:47,680 Speaker 3: Our executive producer at iHeart is Jennifer Bassett. Our theme 1222 01:05:47,800 --> 01:05:50,440 Speaker 3: music is by Eric Deutsch, and our content is for 1223 01:05:50,560 --> 01:05:51,760 Speaker 3: educational purposes only. 1224 01:05:52,720 --> 01:05:55,000 Speaker 2: If you like the show, help other people find us. 1225 01:05:55,320 --> 01:05:58,080 Speaker 2: Leave a rating and review on Apple Podcasts or your 1226 01:05:58,160 --> 01:06:00,919 Speaker 2: podcatcher of choice and help let's spread the word about 1227 01:06:00,920 --> 01:06:04,000 Speaker 2: the show. You can follow us on Instagram at Wellness 1228 01:06:04,000 --> 01:06:07,240 Speaker 2: Actually pod and don't forget We want to hear from you. 1229 01:06:07,600 --> 01:06:10,160 Speaker 2: Head over to Wellness Actually do FM and leave us 1230 01:06:10,160 --> 01:06:12,760 Speaker 2: a question for our mailbag or suggest a topic for 1231 01:06:12,800 --> 01:06:13,439 Speaker 2: a future show. 1232 01:06:13,960 --> 01:06:15,840 Speaker 1: We'll let the influencers have the last word. 1233 01:06:16,040 --> 01:06:18,960 Speaker 6: You cannot trust your pregnant brain. Last week I went 1234 01:06:19,000 --> 01:06:20,800 Speaker 6: to lunch I got there early. I was so proud 1235 01:06:20,800 --> 01:06:22,840 Speaker 6: of myself. So I usually run five to ten minutes late, 1236 01:06:23,280 --> 01:06:27,200 Speaker 6: but I got there ten minutes early. I wait for 1237 01:06:27,280 --> 01:06:30,960 Speaker 6: thirty more minutes am I getting stood up for the 1238 01:06:31,080 --> 01:06:33,320 Speaker 6: very first time in my life. A couple hours later, 1239 01:06:33,480 --> 01:06:35,120 Speaker 6: I get a text from this person and they're like, 1240 01:06:35,200 --> 01:06:37,760 Speaker 6: oh my gosh, we're rating next week. 1241 01:06:38,000 --> 01:06:39,800 Speaker 5: But yeah, I was sad. 1242 01:06:40,320 --> 01:06:52,640 Speaker 6: I heard my own feelings.