WEBVTT - On the Front Lines 

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<v Speaker 1>From Pushkin Industries. This is Deep Background, the show where

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<v Speaker 1>we explore the stories behind the stories in the news.

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<v Speaker 1>I'm Noah Feldman. At the beginning of the COVID nineteen outbreak,

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<v Speaker 1>we spent a lot of time thinking about the doctors,

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<v Speaker 1>the frontline physicians who were fighting the disease in the hospital.

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<v Speaker 1>As cases have begun slowly but surely to decline hebred

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<v Speaker 1>Massachusetts and in other states, we thought it was a

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<v Speaker 1>good time to revisit the frontline hospital doctors and the

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<v Speaker 1>experiences that they've had treating patients in intensive care units.

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<v Speaker 1>We wanted to know what their experience has been and

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<v Speaker 1>how it's been changing over the last several months. We

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<v Speaker 1>also wanted to know about the standard of care in

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<v Speaker 1>the hospitals. It is coronavirus being treated now the same

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<v Speaker 1>way that it was treated at the outset, or have

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<v Speaker 1>there been signific developments in how physicians are encountering patients.

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<v Speaker 1>To discuss these issues, we're joined by doctor Emmy Rubin.

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<v Speaker 1>She's a critical care pulmonologist at Massachusetts General Hospital. She's

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<v Speaker 1>been on the front line treating coronavirus patients from the beginning.

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<v Speaker 1>She's also co chair of the hospital's Optimum Care Committee,

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<v Speaker 1>which is essentially its leading ethics body for figuring out

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<v Speaker 1>how to handle difficult ethical questions under circumstances exactly like

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<v Speaker 1>the ones facing the hospital now. I asked doctor Rubin

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<v Speaker 1>how things have changed in her ICU since March, So

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<v Speaker 1>I would say, you know, in the beginning, when the

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<v Speaker 1>cases were surging, Mass General was particularly hard hit. So

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<v Speaker 1>in the early days, things were evolving very very quickly.

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<v Speaker 1>We were extending our capacity in every way that we

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<v Speaker 1>could very quickly by opening up new ICU spaces within

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<v Speaker 1>the hospitspital adding staff, changing staffing models, and we got

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<v Speaker 1>to the point where we had close to two hundred

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<v Speaker 1>patients with COVID in our intensive care units. So I

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<v Speaker 1>think in terms of how we individually took care of patients,

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<v Speaker 1>we took care of them the way we would take

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<v Speaker 1>care of any IU patient with respiratory failure. And I

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<v Speaker 1>think we relied on what we know about the basic

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<v Speaker 1>physiology of these patients, which is the vast majority of

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<v Speaker 1>them and the intensive care units have what's called acute

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<v Speaker 1>respiratory distress syndrome or AIRDS. That's something that all of

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<v Speaker 1>us have a lot of experience taken care of, and

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<v Speaker 1>we relied on basic principles of management, ventilator management in particular,

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<v Speaker 1>which we know a lot about from other disease processes.

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<v Speaker 1>So in many ways, taking care of individual patients was

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<v Speaker 1>similar to how we take care of individual patients with

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<v Speaker 1>the flu or airds from other conditions. What was not

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<v Speaker 1>typical was obviously the volume of patients with one specific

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<v Speaker 1>condition that months before we had not heard about. What

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<v Speaker 1>was also different was the kinds of medications we were trying.

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<v Speaker 1>At first we were using in the early days, we

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<v Speaker 1>were using a lot of hydroxy chloroquin, a lot of statins.

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<v Speaker 1>I think people were very quickly trialing things. I think

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<v Speaker 1>there was a lot of desire among many people to

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<v Speaker 1>try medications that might work, and has been widely reported.

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<v Speaker 1>I think in the beginning we were using a lot

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<v Speaker 1>of medications that have turned out to be of questionable benefit.

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<v Speaker 1>As things have gone on, there are many many trials

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<v Speaker 1>up and running at Mass General to look at randomized

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<v Speaker 1>controlled trials at these medications and try to figure out

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<v Speaker 1>what actually works and what doesn't. So I would say

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<v Speaker 1>that early kind of enthusiasm for different medications has waned,

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<v Speaker 1>and now really it's just taking care of intensive care

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<v Speaker 1>unipatients with respiratory failure, but on a much larger scale.

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<v Speaker 1>Let me ask you specifically about the what you described

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<v Speaker 1>as your normal practice for people with RDS, which includes

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<v Speaker 1>ventilators right. Has the way that you are treating COVID

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<v Speaker 1>patients in that regard in terms of putting them on ventilators,

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<v Speaker 1>who goes on ventilators at what stage? Remain constant or

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<v Speaker 1>has that shifted? Because I know there was at least

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<v Speaker 1>some public discussion sort of somewhere in April around the

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<v Speaker 1>question of whether the ventilators were doing what they ought

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<v Speaker 1>to be doing for COVID patients or whether it was

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<v Speaker 1>plausible to think about other oxygen delivery systems. How has

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<v Speaker 1>that evolved and are we back to sort of where

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<v Speaker 1>we started in that regard. Yeah, I think an interesting question.

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<v Speaker 1>I would say it may be that early on we

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<v Speaker 1>may have had a lower threshold for putting people on ventilators.

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<v Speaker 1>So one of the things we know about airds is

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<v Speaker 1>that once people are on a ventilator, the mainstay of

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<v Speaker 1>treating them on a ventilator is giving them relatively small

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<v Speaker 1>breaths on the ventilator to prevent what we call ventilator

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<v Speaker 1>induced lung injury. And there's a concern that if people

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<v Speaker 1>with developing ards are breathing on their own and taking large,

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<v Speaker 1>kind of gulping breaths for a long time and they

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<v Speaker 1>end up needing to have a breathing machine anyway, that

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<v Speaker 1>during the time they're breathing spontaneously, they may be doing

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<v Speaker 1>damage to their lungs by taking large breaths and damaging

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<v Speaker 1>certain portions of their lungs. I think in the beginning

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<v Speaker 1>we may have had a slightly lower threshold for putting

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<v Speaker 1>people on a breathing machine. In other words, when people

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<v Speaker 1>seem to be taking a significant turn for the worse,

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<v Speaker 1>we may have put them on a little bit earlier.

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<v Speaker 1>But I would say in general, our management kind of

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<v Speaker 1>adheres to traditional principles, which is, when somebody has respiratory

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<v Speaker 1>failure and is not supporting their breathing, either not maintaining

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<v Speaker 1>their oxygen levels or not getting rid of the carbon

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<v Speaker 1>dioxide they're tiring out, we support their breathing with a ventilator.

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<v Speaker 1>There has been a lot of attention to are we

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<v Speaker 1>putting too many people on ventilators with COVID. I think

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<v Speaker 1>I can speak for myself certainly and for many of

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<v Speaker 1>my colleagues that we feel that you look clinically at

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<v Speaker 1>the patient. If they seem like their breathing is failing,

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<v Speaker 1>we put them on a breathing machine, the same way

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<v Speaker 1>we would in any other situation. And how do you

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<v Speaker 1>feel There must be some statistics on this, but there's

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<v Speaker 1>also some imperfection in the statistical analysis. But how do

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<v Speaker 1>you feel in terms of whether the standard of care

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<v Speaker 1>that you're using is producing better outcomes at this stage

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<v Speaker 1>than it was at the beginning, or really are people

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<v Speaker 1>making it or not making it with the excellent treatment

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<v Speaker 1>that you're giving them pretty much at the same rate

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<v Speaker 1>as they were at the beginning. I realize there are

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<v Speaker 1>many confounding factors that would be very hard to run

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<v Speaker 1>a proper study on this or in movement. So I'm

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<v Speaker 1>really asking you for an impressionistic response. Yeah, As you

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<v Speaker 1>alluded to, the data has essentially all been imperfect because

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<v Speaker 1>we don't have enough long term data on how people

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<v Speaker 1>are doing. So most of the data about for survival

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<v Speaker 1>to discharge, for example, or survival to hospital discharge was

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<v Speaker 1>based on numbers that included a lot of people who

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<v Speaker 1>were still in the ICU. So I think it is

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<v Speaker 1>possible that early on, as they said before, we were

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<v Speaker 1>having a slightly lower threshold to intubate people. So we

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<v Speaker 1>saw a lot of people getting better, getting off the

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<v Speaker 1>breathing machine and getting out of the ICU and in

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<v Speaker 1>many cases leaving the hospital. Now we're seeing a lot

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<v Speaker 1>of people who have required support for a longer period

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<v Speaker 1>of time. We have a lot of patients now. This

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<v Speaker 1>is one way in which things have changed is that

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<v Speaker 1>many of the patients I would say, who remain in

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<v Speaker 1>the intensive care units or in other parts of the

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<v Speaker 1>hospital that are sort of stepped downs from the intensive

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<v Speaker 1>PERI unit are people who we don't know how they'll

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<v Speaker 1>how they'll do, whether they will survive, whether they will

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<v Speaker 1>survived to leave the hospital, whether they'll be able to

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<v Speaker 1>get successfully off of the VENTI later. So I think

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<v Speaker 1>things have evolved in that respect that we anticipate that.

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<v Speaker 1>You know, when we looked at our earlier percentages of

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<v Speaker 1>people who had survived to hospital discharge, those were quite encouraging.

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<v Speaker 1>We always expected those numbers to change and to sort

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<v Speaker 1>of move more towards the numbers that we are familiar

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<v Speaker 1>with for airds in general, and the mortality rate for

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<v Speaker 1>airds in general is high. What's the ballpark for air

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<v Speaker 1>ds in general non COVID airdas I think for moderate

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<v Speaker 1>to severe airds there's about a forty percent mortality rate,

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<v Speaker 1>and age is a predictor of mortality for airds in general.

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<v Speaker 1>And so again that's a way in which we think

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<v Speaker 1>that this will be quite similar. What's the longest that

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<v Speaker 1>you've had people still beyond ventilators? I mean there must

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<v Speaker 1>be people who came in in March. Yeah, are any

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<v Speaker 1>of those people still on ventilators now? Yes, there are

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<v Speaker 1>certainly people who came in March who are still needing

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<v Speaker 1>ventilator supports. So typically, once somebody needs support for a

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<v Speaker 1>certain period of time that is defined by sort of

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<v Speaker 1>clinical judgment, but more than a couple of weeks generally,

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<v Speaker 1>and we consider putting a trade gastome and which is

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<v Speaker 1>a more durable, more comfortable form of a breathing tube,

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<v Speaker 1>so that patients can receive mechanical ventilation for longer. There

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<v Speaker 1>are many patients now who have had trade gustomes, some

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<v Speaker 1>of whom will then be liberated from the ventilator once

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<v Speaker 1>they have the trade gastomies. But there are certainly patients

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<v Speaker 1>who have required many, many weeks of mechanical ventilation. Some

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<v Speaker 1>of those patients will leave the hospital and go to

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<v Speaker 1>sort of long term acute care hospitals even while they're

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<v Speaker 1>still needing support. There are certainly patients in that category,

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<v Speaker 1>and that is not unique to COVID. I think what

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<v Speaker 1>is unique is the number of people. So when you

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<v Speaker 1>start with ten times the number of people who you

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<v Speaker 1>ordinarily have with AIRDS, you're going to have a huge

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<v Speaker 1>number of people in the category of what we call

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<v Speaker 1>chronic critical illness, where people require prolonged mechanical ventilation. It

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<v Speaker 1>sounds like a remdesse of her which I finderstand correctly

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<v Speaker 1>has been made available at least at MGH, is not

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<v Speaker 1>having a transformative impact on the course of disease for

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<v Speaker 1>most of the patients that you're seeing. I think, based

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<v Speaker 1>on my understanding of the data, and I think in

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<v Speaker 1>general this is a shared view, that it does have

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<v Speaker 1>some effect, apparently on sort of time to recovery. I

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<v Speaker 1>don't think there's a sense that it will be a

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<v Speaker 1>game changer for the people who are the sickest. We

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<v Speaker 1>are giving it and it is the only drug, as

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<v Speaker 1>you I'm sure are aware that is now not formally

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<v Speaker 1>approved but authorized use. So we are certainly giving it

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<v Speaker 1>to patients who meet criteria for it. I think the

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<v Speaker 1>patients who, for whatever reasons, are destined to become the sickest.

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<v Speaker 1>I don't know that it will help prevent severe illness

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<v Speaker 1>or deaf in those patients. There was, as you probably

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<v Speaker 1>also know, a trend towards mortality in that in the trial,

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<v Speaker 1>but it wasn't didn't meet technically the threshold for statistical significance,

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<v Speaker 1>and I don't necessarily think we'll get answers to those questions.

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<v Speaker 1>By the time we got round severe, we had a

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<v Speaker 1>hospital full of people who were already, as I said,

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<v Speaker 1>sort of very far advanced into the illness. I think

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<v Speaker 1>we're very skeptical that it could help those patients. So

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<v Speaker 1>I think we think that a certain subset of patients

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<v Speaker 1>who get it early enough on the severity illness may

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<v Speaker 1>be less, which is encouraging. It's encouraging to have something

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<v Speaker 1>to use, but we still think that for certain patients

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<v Speaker 1>this is a devastating illness and will be. And when

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<v Speaker 1>Donald Trump informed us that he was taking hydroxy chloroquinn,

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<v Speaker 1>one of the things that he said was that his

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<v Speaker 1>impression was that lots of frontline medical workers were also

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<v Speaker 1>taking it prophylactically in your anecdotal experience at MGH, Do

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<v Speaker 1>you know anybody who's actually doing that at the stage,

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<v Speaker 1>I cannot promise it's not happening. I do not know

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<v Speaker 1>anyone that personally, to be perfectly honest, did it come

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<v Speaker 1>up with people at the very beginning when it was

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<v Speaker 1>being used. It didn't. I don't know that any of

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<v Speaker 1>my friends and colleagues ever actually took it, but there

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<v Speaker 1>were some people who mentioned early on that they would

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<v Speaker 1>consider it when there was a lot of enthusiasm for it.

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<v Speaker 1>Certainly not in recent days. And again I think it's

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<v Speaker 1>you know, a lot of what we've seen, and I

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<v Speaker 1>think it's human nature to want to do something for

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<v Speaker 1>people who are so sick in front of you, So

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<v Speaker 1>I don't. I think one of the things that's been

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<v Speaker 1>very interesting and that sort of consistent with human nature,

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<v Speaker 1>is that throughout the course of this the zeal to

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<v Speaker 1>use things that sort of seem like they might plausibly help,

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<v Speaker 1>or where there's a little bit of suggestion of it,

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<v Speaker 1>like hydrox chloroquint at the beginning. I mean, that was

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<v Speaker 1>very very thoughtful, smart people. We're using that and recommending

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<v Speaker 1>using it at the beginning. I think that's just a

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<v Speaker 1>testament to how much people want to find something to help.

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<v Speaker 1>And I think, you know, hopefully now we've sort of

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<v Speaker 1>regressed to the point where we're you know, I think

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<v Speaker 1>most people are being much more measured about we need

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<v Speaker 1>to study things in the context of trials and actually

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<v Speaker 1>get evidence before using things. But you know, it's understandable.

0:12:38.596 --> 0:12:41.756
<v Speaker 1>It's very hard to watch people sick and dying in

0:12:41.756 --> 0:12:44.316
<v Speaker 1>front of you with nothing to do other than sort

0:12:44.316 --> 0:12:46.916
<v Speaker 1>of supportive care, which really is the sort of mainstay

0:12:46.916 --> 0:12:49.196
<v Speaker 1>of taking care of these people. That's something that you know,

0:12:49.236 --> 0:12:52.036
<v Speaker 1>as I see, physicians were used to because there are

0:12:52.036 --> 0:12:55.156
<v Speaker 1>many things that we don't have a specific magic bullet

0:12:55.196 --> 0:12:58.836
<v Speaker 1>for and we take time and you know, try to

0:12:58.876 --> 0:13:01.356
<v Speaker 1>have patience and try to get people through it with

0:13:01.396 --> 0:13:04.476
<v Speaker 1>sort of the best supportive management we can. But it's hard.

0:13:05.276 --> 0:13:18.276
<v Speaker 1>We'll be right back. How has the psychological experience of

0:13:18.316 --> 0:13:21.596
<v Speaker 1>being a critical care physician been changing for you? At

0:13:21.636 --> 0:13:24.876
<v Speaker 1>the beginning, it must have been just a bit overwhelming

0:13:24.916 --> 0:13:28.796
<v Speaker 1>because of the radical numbers and the changes. I'm curious

0:13:28.836 --> 0:13:30.916
<v Speaker 1>to know what it was like then, and also how

0:13:30.916 --> 0:13:35.156
<v Speaker 1>it's evolving now. Yeah, it's a good question. I think

0:13:35.156 --> 0:13:38.436
<v Speaker 1>at the beginning, first of all, I think, you know,

0:13:38.436 --> 0:13:41.396
<v Speaker 1>there's a whole lot of adrenaline around sort of, you know,

0:13:41.636 --> 0:13:45.036
<v Speaker 1>there always is when something is evolving so quickly. I

0:13:45.076 --> 0:13:49.396
<v Speaker 1>think there was a lot of energy around everybody figuring

0:13:49.396 --> 0:13:52.236
<v Speaker 1>out how to make this work and extending our capacity,

0:13:52.316 --> 0:13:55.596
<v Speaker 1>and everybody jumping in and filling roles that they may

0:13:55.636 --> 0:13:58.236
<v Speaker 1>not have otherwise filled. I think there was a lot

0:13:58.236 --> 0:14:00.356
<v Speaker 1>of energy around how do we, you know, kind of

0:14:00.356 --> 0:14:03.356
<v Speaker 1>step up to this moment that is unusual. I think

0:14:03.356 --> 0:14:05.436
<v Speaker 1>there was also sort of an element that was very

0:14:05.476 --> 0:14:07.276
<v Speaker 1>surreal the first time I was in an ICU and

0:14:07.316 --> 0:14:09.836
<v Speaker 1>all of a sudden, every single patient has a disease

0:14:10.356 --> 0:14:12.596
<v Speaker 1>that you know, we didn't know the name of a

0:14:12.596 --> 0:14:14.596
<v Speaker 1>few months ago. So I think there was an element

0:14:14.636 --> 0:14:19.276
<v Speaker 1>of feeling like it was hard to believe it was happening.

0:14:20.836 --> 0:14:23.716
<v Speaker 1>There was not a lot a lot of time necessarily

0:14:23.756 --> 0:14:25.876
<v Speaker 1>spent on rounds trying to figure out what was happening.

0:14:25.956 --> 0:14:29.156
<v Speaker 1>So I would say in general rounding in the intensive

0:14:29.156 --> 0:14:31.396
<v Speaker 1>care unit, one of the things that was noticeable is

0:14:31.436 --> 0:14:34.396
<v Speaker 1>that sort of took less time. Everybody was quite similar

0:14:34.636 --> 0:14:37.196
<v Speaker 1>in terms of what was wrong and the kinds of

0:14:37.196 --> 0:14:38.956
<v Speaker 1>decisions you were making, so there wasn't a lot of

0:14:38.996 --> 0:14:43.396
<v Speaker 1>diagnostic dilemma, which was unusual. And also, you know, I

0:14:43.436 --> 0:14:45.156
<v Speaker 1>think made things kind of go a little bit faster.

0:14:45.316 --> 0:14:47.396
<v Speaker 1>You would go around taking care of the patients making

0:14:47.476 --> 0:14:50.236
<v Speaker 1>kind of similar decisions. Examining people took a lot longer

0:14:50.276 --> 0:14:52.556
<v Speaker 1>because you were dealing with you know, gear that is

0:14:52.916 --> 0:14:54.836
<v Speaker 1>more time consuming to put on and take off and

0:14:54.996 --> 0:14:56.996
<v Speaker 1>figure out where to put everything and do things safely.

0:14:57.436 --> 0:14:59.756
<v Speaker 1>But the actual medicine I would say took less time,

0:14:59.796 --> 0:15:02.596
<v Speaker 1>both because most of the patients were similar in a

0:15:02.636 --> 0:15:06.516
<v Speaker 1>lot of ways, and also because families weren't there, and

0:15:06.556 --> 0:15:09.036
<v Speaker 1>the time that you would ordinarily take either on rounds

0:15:09.196 --> 0:15:12.196
<v Speaker 1>after rounds, to be talking to families and explaining things

0:15:12.676 --> 0:15:15.996
<v Speaker 1>you didn't have to take. I would say that is

0:15:15.996 --> 0:15:19.036
<v Speaker 1>a significant change for a whole lot of reasons. Does

0:15:19.036 --> 0:15:20.436
<v Speaker 1>it make it easier, I mean, I know it's not

0:15:20.516 --> 0:15:22.316
<v Speaker 1>great for the families, But does it make it easier

0:15:22.356 --> 0:15:24.356
<v Speaker 1>for the physicians through their jobs. Well, yes, so in

0:15:24.396 --> 0:15:28.556
<v Speaker 1>certain ways that made things sort of more streamlined. In

0:15:28.556 --> 0:15:31.876
<v Speaker 1>other ways, I think it's made things incredibly challenging a

0:15:31.876 --> 0:15:34.916
<v Speaker 1>lot of what we do as I see doctors, nurses,

0:15:35.036 --> 0:15:39.596
<v Speaker 1>other people who work in the ICU, is talking to families,

0:15:39.676 --> 0:15:43.636
<v Speaker 1>having conversations about what's important, what direction to take, a

0:15:43.636 --> 0:15:47.676
<v Speaker 1>lot of end of life discussions that are very, very challenging,

0:15:47.796 --> 0:15:51.276
<v Speaker 1>I think, to have over the phone, we rely a

0:15:51.276 --> 0:15:56.796
<v Speaker 1>lot on developing fairly quick rapport with families. In person,

0:15:57.276 --> 0:15:59.196
<v Speaker 1>we rely a lot on, or at least I should

0:15:59.196 --> 0:16:02.876
<v Speaker 1>speak for myself, I rely a lot on nonverbal communication

0:16:02.996 --> 0:16:05.636
<v Speaker 1>and things that are really challenging over the phone, and

0:16:05.636 --> 0:16:08.916
<v Speaker 1>I would say, particularly where they're language barriers, I would

0:16:08.916 --> 0:16:15.396
<v Speaker 1>say those conversations have been much more difficult for me,

0:16:15.596 --> 0:16:19.716
<v Speaker 1>certainly not being able to see families regularly in person.

0:16:20.076 --> 0:16:22.756
<v Speaker 1>We have had families come in when patients are approaching

0:16:22.836 --> 0:16:24.556
<v Speaker 1>or at the end of life, which I think has

0:16:24.556 --> 0:16:29.116
<v Speaker 1>been helpful. That ordinarily, when somebody is so sick, it's

0:16:29.156 --> 0:16:31.956
<v Speaker 1>an evolving process over a period of time and a

0:16:32.036 --> 0:16:36.516
<v Speaker 1>number of conversations that involves establishing trust and coming back

0:16:36.556 --> 0:16:39.756
<v Speaker 1>to things, and so that's been really really challenging, I

0:16:39.796 --> 0:16:42.476
<v Speaker 1>think not having families there regularly, and of course that's

0:16:42.476 --> 0:16:44.916
<v Speaker 1>something we do with some families can't for various reasons

0:16:45.396 --> 0:16:48.756
<v Speaker 1>or aren't in the ICU routinely when a loved one

0:16:48.796 --> 0:16:52.956
<v Speaker 1>is sick. But this is a fairly dramatic departure, having

0:16:53.076 --> 0:16:57.436
<v Speaker 1>very few family members present. What about your morale and

0:16:57.436 --> 0:16:59.836
<v Speaker 1>the moral of your colleagues. I mean, as you're describing

0:16:59.836 --> 0:17:01.996
<v Speaker 1>at the beginning, there's a lot of adrenaline and so

0:17:02.036 --> 0:17:04.396
<v Speaker 1>that in some sense takes care of the moral. You know,

0:17:04.436 --> 0:17:06.676
<v Speaker 1>what you have to do, the pressures on you do

0:17:06.756 --> 0:17:09.236
<v Speaker 1>it now that things are maybe by your description a

0:17:09.276 --> 0:17:13.596
<v Speaker 1>little bit more regularized or routinized, the how's your inner

0:17:13.996 --> 0:17:15.476
<v Speaker 1>experience of that, and what do you think about that

0:17:15.556 --> 0:17:21.876
<v Speaker 1>of your colleagues? Yeah, I think people are exhausted. I

0:17:21.916 --> 0:17:24.636
<v Speaker 1>think we also have no idea now sort of what

0:17:24.676 --> 0:17:26.716
<v Speaker 1>form this is going to take going forward. I think

0:17:26.796 --> 0:17:29.516
<v Speaker 1>it was you know, it has become clear that this

0:17:29.636 --> 0:17:34.116
<v Speaker 1>is not going away in any meaningful way anytime soon.

0:17:35.036 --> 0:17:37.596
<v Speaker 1>While there is certainly the numbers are down dramatically in

0:17:37.676 --> 0:17:39.956
<v Speaker 1>terms of the intensive care unit, you know, the number

0:17:39.996 --> 0:17:41.796
<v Speaker 1>of patients. As I said before, we have a lot

0:17:41.836 --> 0:17:44.116
<v Speaker 1>of patients who are still very sick in the hospital,

0:17:44.156 --> 0:17:48.036
<v Speaker 1>who are kind of living through the sequela of critical illness.

0:17:48.636 --> 0:17:50.636
<v Speaker 1>We don't know what's going to happen to the numbers,

0:17:50.956 --> 0:17:53.916
<v Speaker 1>you know, next month or in the fall or during

0:17:53.916 --> 0:17:58.156
<v Speaker 1>flu season. I think people are exhausted. There are many

0:17:58.196 --> 0:18:01.396
<v Speaker 1>ways in which this has been a very hard to

0:18:01.636 --> 0:18:04.796
<v Speaker 1>be a part of. I think the fact that this

0:18:05.036 --> 0:18:08.276
<v Speaker 1>that COVID has hit communities of color so much harder,

0:18:09.476 --> 0:18:12.676
<v Speaker 1>and you know, we're just watching person after person come

0:18:12.716 --> 0:18:15.316
<v Speaker 1>in incredibly sick. And you know, as I said before,

0:18:15.396 --> 0:18:17.156
<v Speaker 1>much of what we can do in the US supportive

0:18:17.196 --> 0:18:20.636
<v Speaker 1>care and time and patience and taking the best care

0:18:20.676 --> 0:18:22.276
<v Speaker 1>of people we can and seeing if they get better.

0:18:22.796 --> 0:18:26.156
<v Speaker 1>It's felt pretty relentless in terms of people coming in,

0:18:26.196 --> 0:18:29.156
<v Speaker 1>often from the similar communities. Often, you know, we've seen

0:18:29.276 --> 0:18:32.956
<v Speaker 1>multiple members of a family be critically ill. I think

0:18:33.036 --> 0:18:37.476
<v Speaker 1>it's you know, the scope of the tragedy of it is,

0:18:37.836 --> 0:18:41.196
<v Speaker 1>you know, demoralizing and exhausting and very sad. And I

0:18:41.236 --> 0:18:44.236
<v Speaker 1>think people are physically tired because this is hard work

0:18:44.276 --> 0:18:47.996
<v Speaker 1>and everybody's generally doing more of it than they typically would,

0:18:48.516 --> 0:18:53.556
<v Speaker 1>and also emotionally exhausted because we in this you know,

0:18:53.636 --> 0:18:56.516
<v Speaker 1>line of work, we see a lot of people die

0:18:56.596 --> 0:18:58.676
<v Speaker 1>in general. That's why we're used to But I think

0:18:59.476 --> 0:19:02.076
<v Speaker 1>all of this happening all at once in such large numbers.

0:19:02.236 --> 0:19:05.116
<v Speaker 1>I think has been really hard. I can certainly say

0:19:05.156 --> 0:19:09.556
<v Speaker 1>for myself personally, you know, the uncertainties of or where

0:19:09.556 --> 0:19:11.756
<v Speaker 1>it will go from here and what will happen and

0:19:11.796 --> 0:19:13.716
<v Speaker 1>when we be in the same position a few months

0:19:13.716 --> 0:19:20.636
<v Speaker 1>from now, it's just it's exhausting. If there's a second wave,

0:19:21.196 --> 0:19:22.876
<v Speaker 1>it sounds like from what you're saying that under the

0:19:22.876 --> 0:19:25.476
<v Speaker 1>standard of care, we're going to need a lot of ventilators.

0:19:26.196 --> 0:19:28.796
<v Speaker 1>Do you have the sense working in the hospital that

0:19:28.876 --> 0:19:31.476
<v Speaker 1>there will be enough should that occur? I mean, how

0:19:31.516 --> 0:19:34.596
<v Speaker 1>close to breaking point were you at, you know, one

0:19:34.636 --> 0:19:36.796
<v Speaker 1>of the great hospitals in the region and indeed in

0:19:36.796 --> 0:19:40.436
<v Speaker 1>the world. I would say we certainly, you know, we

0:19:40.596 --> 0:19:45.756
<v Speaker 1>extended our capacity many many fold. We did not get

0:19:45.796 --> 0:19:47.996
<v Speaker 1>close to the point where we were out of ventilators.

0:19:47.996 --> 0:19:49.596
<v Speaker 1>I think there was a period of time wherewith the

0:19:49.596 --> 0:19:53.116
<v Speaker 1>trajectory of cases, we were concerned that we might and

0:19:53.196 --> 0:19:56.476
<v Speaker 1>so I think in the end, I think because of

0:19:56.516 --> 0:19:58.876
<v Speaker 1>measures that were taken and people staying at home, things

0:19:58.916 --> 0:20:03.396
<v Speaker 1>flattened out enough that we fortunately avoided that. And I

0:20:03.396 --> 0:20:08.356
<v Speaker 1>would hope that now that that was a concern that

0:20:08.796 --> 0:20:10.916
<v Speaker 1>you know, an interim and you know, again I don't

0:20:10.956 --> 0:20:13.476
<v Speaker 1>have a I don't know anything more than you do

0:20:13.516 --> 0:20:15.316
<v Speaker 1>about whether there'll be a second wave, but I certainly

0:20:15.356 --> 0:20:18.556
<v Speaker 1>think people are concerned that there could be. I think

0:20:18.596 --> 0:20:21.316
<v Speaker 1>between all of the lessons we learned among all the

0:20:21.356 --> 0:20:25.996
<v Speaker 1>institutions about sort of balancing loads across hospitals, you know,

0:20:26.036 --> 0:20:29.436
<v Speaker 1>acquisition of new supplies, hopefully we would be and I

0:20:29.436 --> 0:20:31.556
<v Speaker 1>think we will be better prepared if there is a

0:20:31.596 --> 0:20:34.676
<v Speaker 1>second wave. And the answer to that question certainly depends

0:20:34.676 --> 0:20:37.876
<v Speaker 1>on how large a wave would there be. I think

0:20:37.876 --> 0:20:39.996
<v Speaker 1>if there is a second wave of the type that

0:20:40.036 --> 0:20:42.556
<v Speaker 1>we saw, we will be prepared for that. You know,

0:20:42.996 --> 0:20:45.596
<v Speaker 1>there's always a worst case scenario that you can imagine

0:20:45.636 --> 0:20:49.316
<v Speaker 1>that would still overwhelm capacity, but I would say we

0:20:49.476 --> 0:20:53.596
<v Speaker 1>ended up being pretty far from that. While we were,

0:20:53.596 --> 0:20:56.676
<v Speaker 1>you know, we're stretched in terms of our capacity, we

0:20:56.676 --> 0:21:00.676
<v Speaker 1>weren't near the breaking point. So hopefully that would be

0:21:00.756 --> 0:21:03.316
<v Speaker 1>even more true the next time around, because there's been

0:21:03.316 --> 0:21:06.636
<v Speaker 1>a lot of lessons learned about how to organize across

0:21:06.676 --> 0:21:09.356
<v Speaker 1>the system and extend capacity not just within a vidual

0:21:09.436 --> 0:21:13.396
<v Speaker 1>hospital but across the region and the state. So my

0:21:13.476 --> 0:21:17.956
<v Speaker 1>hope would be we would never get there in this pandemic.

0:21:18.356 --> 0:21:20.996
<v Speaker 1>But again, it depends on you know, there's always a

0:21:21.036 --> 0:21:24.196
<v Speaker 1>worst case scenario. You can imagine where we would get there.

0:21:25.796 --> 0:21:27.396
<v Speaker 1>What have I not asked you that I ought to

0:21:27.436 --> 0:21:30.596
<v Speaker 1>be asking you? I guess the thing to be asking

0:21:32.236 --> 0:21:34.996
<v Speaker 1>in some ways is sort of what are the issues?

0:21:35.556 --> 0:21:38.236
<v Speaker 1>You know? Kind of going forward? Right? We sort of

0:21:38.236 --> 0:21:42.236
<v Speaker 1>have dealt with this emergently and quickly, and everybody's done

0:21:42.276 --> 0:21:43.956
<v Speaker 1>the best they can. And I would say people have

0:21:43.956 --> 0:21:49.116
<v Speaker 1>done an incredible job of stepping forward and being innovative

0:21:49.116 --> 0:21:50.876
<v Speaker 1>and thinking about how do we best take care of people?

0:21:50.916 --> 0:21:52.556
<v Speaker 1>How do we learn as much as possible, how do

0:21:52.596 --> 0:21:56.676
<v Speaker 1>we change the whole way that we practice medicine in

0:21:56.716 --> 0:21:59.756
<v Speaker 1>a very quick period of time. And it's been incredible

0:21:59.876 --> 0:22:01.436
<v Speaker 1>to watch that. I think there are a lot of

0:22:01.516 --> 0:22:04.836
<v Speaker 1>challenges ahead, and one of them, you know, one of

0:22:04.876 --> 0:22:07.436
<v Speaker 1>the big ones I think has to do with how

0:22:07.436 --> 0:22:09.276
<v Speaker 1>do we take care? As I say before, we have

0:22:09.276 --> 0:22:11.956
<v Speaker 1>an exponentially larger number of patients who are going to

0:22:11.996 --> 0:22:15.756
<v Speaker 1>be dealing with the consequences of critical illness. People who

0:22:15.756 --> 0:22:18.516
<v Speaker 1>survive a prolonged period of critical illness generally do not

0:22:18.836 --> 0:22:22.516
<v Speaker 1>you bounce back immediately. And we now have a whole

0:22:22.516 --> 0:22:24.756
<v Speaker 1>lot of patients who have been incredibly sick, who will

0:22:24.796 --> 0:22:28.116
<v Speaker 1>be dealing with the consequences of that for a very

0:22:28.156 --> 0:22:32.076
<v Speaker 1>long time, whether it's being you know, in the hospital

0:22:32.116 --> 0:22:35.196
<v Speaker 1>now for many many more weeks, two months, being in

0:22:35.236 --> 0:22:38.956
<v Speaker 1>and out of rehabs or long term acute care hospitals.

0:22:38.956 --> 0:22:41.916
<v Speaker 1>How do we ensure that there's a frameworkingplace to take

0:22:41.956 --> 0:22:45.036
<v Speaker 1>care of those patients. That system was already very stretched

0:22:45.316 --> 0:22:47.716
<v Speaker 1>to begin with. It was often very hard to find

0:22:48.196 --> 0:22:51.916
<v Speaker 1>appropriate places for people to go following episodes of critical illness,

0:22:52.716 --> 0:22:56.996
<v Speaker 1>and that system will now be stretched even more, and

0:22:57.076 --> 0:22:58.996
<v Speaker 1>so I think a lot of the questions going forward

0:22:58.996 --> 0:23:01.876
<v Speaker 1>will be how do we do right by all of

0:23:01.876 --> 0:23:06.116
<v Speaker 1>these people who have been so sick. I think people

0:23:06.156 --> 0:23:08.756
<v Speaker 1>focus on do people leave the ICU, do people leave

0:23:08.796 --> 0:23:11.876
<v Speaker 1>the hospital? But there's a whole cascade of things that

0:23:11.916 --> 0:23:17.756
<v Speaker 1>happen after critical illness, both physical, psychological, financial, that I

0:23:17.796 --> 0:23:20.516
<v Speaker 1>think is sort of the next at least for my

0:23:21.196 --> 0:23:25.316
<v Speaker 1>subspecialty in terms of sort of ethical issues. I think

0:23:25.396 --> 0:23:27.756
<v Speaker 1>that becomes a huge issue is how do we take

0:23:27.796 --> 0:23:29.676
<v Speaker 1>care of the people who have been affected by this

0:23:29.796 --> 0:23:33.676
<v Speaker 1>going forward? And that's what I worry about a lot,

0:23:34.276 --> 0:23:36.516
<v Speaker 1>is how are we going to make sure that they're

0:23:36.636 --> 0:23:38.916
<v Speaker 1>taking care of, and recovery goes, you know, sort of

0:23:38.916 --> 0:23:42.716
<v Speaker 1>well beyond the hospital stay, and so how do we

0:23:42.796 --> 0:23:44.756
<v Speaker 1>make sure those people have access to the resources that

0:23:44.796 --> 0:23:48.156
<v Speaker 1>they need and that they can get back to their

0:23:48.356 --> 0:23:50.716
<v Speaker 1>lives if they're able to recover from the critical illness.

0:23:50.716 --> 0:23:52.676
<v Speaker 1>So I think, to me, that's sort of the big

0:23:52.716 --> 0:23:55.636
<v Speaker 1>thing to be thinking about from my standpoint, one of

0:23:55.676 --> 0:23:57.996
<v Speaker 1>the big things to be thinking about going forward. Thank

0:23:58.036 --> 0:24:00.076
<v Speaker 1>you so much for the work that you're doing. We're

0:24:00.196 --> 0:24:02.436
<v Speaker 1>very fortunate that there are people like you who've trained

0:24:02.636 --> 0:24:05.636
<v Speaker 1>in the things that turn out to be essential in

0:24:05.676 --> 0:24:07.996
<v Speaker 1>a crisis like this, and I want to thank you

0:24:08.036 --> 0:24:10.556
<v Speaker 1>for your analysis, for your candor, and also for the

0:24:10.636 --> 0:24:13.196
<v Speaker 1>extraordinary work you've been doing. Sure, thanks a lot. Thanks

0:24:13.236 --> 0:24:17.036
<v Speaker 1>for having me on speaking to doctor Emmy Rubin. I

0:24:17.156 --> 0:24:21.596
<v Speaker 1>was really struck at how the intense adrenaline driven struggle

0:24:21.676 --> 0:24:24.756
<v Speaker 1>of the early days of fighting the coronavirus pandemic in

0:24:24.836 --> 0:24:28.556
<v Speaker 1>her ICU sounds like it has slowly developed into something

0:24:28.636 --> 0:24:32.316
<v Speaker 1>like a new normal. On the one hand, that means

0:24:32.316 --> 0:24:35.076
<v Speaker 1>that the standard of care has to a certain extent solidified.

0:24:35.636 --> 0:24:39.596
<v Speaker 1>No longer are the physicians haphazardly trying every possible drug

0:24:39.636 --> 0:24:43.996
<v Speaker 1>in the hope that something will work. Instead, they're engaged informalized,

0:24:44.556 --> 0:24:49.316
<v Speaker 1>randomized clinical trials of different drugs. Yet simultaneously, it sounds

0:24:49.316 --> 0:24:51.756
<v Speaker 1>as though even remdesevere, the drug that has done best

0:24:51.796 --> 0:24:55.236
<v Speaker 1>so far in those trials, is not being experienced within

0:24:55.356 --> 0:24:57.916
<v Speaker 1>the hospital as any kind of a magic bullet, but

0:24:58.036 --> 0:25:00.916
<v Speaker 1>rather as a mild improvement for some patience, and possibly

0:25:01.196 --> 0:25:05.196
<v Speaker 1>not for the sickest patience who are still in the hospital. Meanwhile,

0:25:05.716 --> 0:25:07.916
<v Speaker 1>dealing with all of the suffering and all of the

0:25:07.996 --> 0:25:13.516
<v Speaker 1>death has been demoralizing and challenging for physicians and unquestionably

0:25:13.556 --> 0:25:18.036
<v Speaker 1>exhausting for them. Listening to doctor Ruben's description, one can

0:25:18.116 --> 0:25:21.516
<v Speaker 1>only hope that a slowing down in new cases gives

0:25:21.596 --> 0:25:24.716
<v Speaker 1>a break to the physicians in the ICUs who are

0:25:24.756 --> 0:25:29.516
<v Speaker 1>dealing with this extraordinarily challenging process of treatment. Because if

0:25:29.516 --> 0:25:31.516
<v Speaker 1>there is a second wave, we're going to be relying

0:25:31.556 --> 0:25:34.636
<v Speaker 1>on exactly the same set of physicians to go to

0:25:34.676 --> 0:25:39.116
<v Speaker 1>the front lines and do it all over again. We're

0:25:39.116 --> 0:25:43.036
<v Speaker 1>also going to need ventilators. Even though ventilators have not

0:25:43.156 --> 0:25:45.676
<v Speaker 1>been in the forefront of the news in recent weeks,

0:25:45.836 --> 0:25:47.876
<v Speaker 1>it turns out that that is not because they are

0:25:47.916 --> 0:25:52.036
<v Speaker 1>somehow less important to treatment than was originally thought. They're

0:25:52.076 --> 0:25:55.356
<v Speaker 1>just as significant to the basic treatment mechanisms. And again,

0:25:55.676 --> 0:25:57.996
<v Speaker 1>if we have a resurgence, we're going to be discussing

0:25:58.116 --> 0:26:02.756
<v Speaker 1>once more whether we have enough ventilators to treat everybody.

0:26:03.036 --> 0:26:05.276
<v Speaker 1>My final thought, and I've had it before in speaking

0:26:05.316 --> 0:26:09.756
<v Speaker 1>to frontline physicians on Deep Background, We're just extraordinarily fortunate

0:26:09.796 --> 0:26:12.996
<v Speaker 1>as a society to have people like doctor Reuben who

0:26:13.076 --> 0:26:16.236
<v Speaker 1>spent their whole careers preparing for moments like this one

0:26:16.556 --> 0:26:20.316
<v Speaker 1>without any knowledge that suddenly pulmonary care would be at

0:26:20.356 --> 0:26:24.516
<v Speaker 1>the forefront of our treatment of the global pandemic. We

0:26:24.596 --> 0:26:27.476
<v Speaker 1>are relying very heavily on a certain group of people

0:26:27.596 --> 0:26:30.796
<v Speaker 1>specialized knowledge right now. But the truth is that in

0:26:30.836 --> 0:26:34.076
<v Speaker 1>any crisis, some group of people who are properly trained

0:26:34.316 --> 0:26:36.876
<v Speaker 1>will rise to the foe and become the people we

0:26:37.276 --> 0:26:40.316
<v Speaker 1>depend on, and for that we can only be thankful.

0:26:41.196 --> 0:26:43.556
<v Speaker 1>Until the next time I speak to you, Be careful,

0:26:43.996 --> 0:26:49.756
<v Speaker 1>be safe, and be well. Deep Background is brought to

0:26:49.836 --> 0:26:53.316
<v Speaker 1>you by Pushkin Industries. Our producer is Lydia Jane Cott,

0:26:53.516 --> 0:26:56.676
<v Speaker 1>with research help from zooi Win and mastering by Jason

0:26:56.716 --> 0:27:01.396
<v Speaker 1>Gambrel and Martin Gonzalez. Our showrunner is Sophie mckibbon. Our

0:27:01.436 --> 0:27:04.596
<v Speaker 1>theme music is composed by Luis Guerra. Special thanks to

0:27:04.636 --> 0:27:08.276
<v Speaker 1>the Pushkin Brass, Malcolm Gladwell, Jacob Weisberg, and Mia Lobel.

0:27:09.116 --> 0:27:11.876
<v Speaker 1>I'm Noah Feldman. I also write a regular column for

0:27:11.996 --> 0:27:15.436
<v Speaker 1>Bloomberg Opinion, which you can find at Bloomberg dot com

0:27:15.436 --> 0:27:19.716
<v Speaker 1>slash Feldman. To discover Bloomberg's original slate of podcasts, go

0:27:19.796 --> 0:27:23.996
<v Speaker 1>to Bloomberg dot com slash podcasts. And one last thing,

0:27:24.476 --> 0:27:27.596
<v Speaker 1>I just wrote a book called The Arab Winter, a Tragedy.

0:27:27.996 --> 0:27:29.916
<v Speaker 1>I would be delighted if you checked it out. You

0:27:29.956 --> 0:27:31.596
<v Speaker 1>can always let me know what you think on Twitter

0:27:31.836 --> 0:27:34.796
<v Speaker 1>about this episode, or the book or anything else. My

0:27:34.876 --> 0:27:38.516
<v Speaker 1>handle is Noah R. Feldman. This is deep background