1 00:00:02,040 --> 00:00:07,600 Speaker 1: Welcome to brain stuff from how stuff works. Hey, brain stuff, 2 00:00:07,600 --> 00:00:13,200 Speaker 1: it's Christian Seger. Goldfish don't need teeny tiny moonshine stills. 3 00:00:13,200 --> 00:00:17,440 Speaker 1: These little guys they can actually handle homebrewing all by themselves, 4 00:00:17,800 --> 00:00:21,320 Speaker 1: as evidenced by the findings of a recent study published 5 00:00:21,320 --> 00:00:26,160 Speaker 1: in the journal Scientific Reports. Although they don't distill whiskey, 6 00:00:26,280 --> 00:00:29,680 Speaker 1: Goldfish have long been known for their ability to make 7 00:00:29,800 --> 00:00:34,200 Speaker 1: their own alcohol. Until now, though, scientists have puzzled over 8 00:00:34,520 --> 00:00:38,160 Speaker 1: how they manage this phenomenon. So why would a fish 9 00:00:38,360 --> 00:00:41,480 Speaker 1: need to make alcohol? The ability is seen in both 10 00:00:41,600 --> 00:00:46,199 Speaker 1: goldfish and it's wild relative, the Crucian carp Both are 11 00:00:46,240 --> 00:00:50,800 Speaker 1: from the genus Kara sous, which often live in conditions 12 00:00:50,840 --> 00:00:55,279 Speaker 1: that would be completely unthinkable for other species. Typically, a 13 00:00:55,360 --> 00:00:59,240 Speaker 1: vertebrate can only survive minutes without oxygen, but these species 14 00:00:59,280 --> 00:01:02,040 Speaker 1: have evolved to the point where they can last four 15 00:01:02,280 --> 00:01:07,160 Speaker 1: or five months in oxygen deprived environments like the bottoms 16 00:01:07,200 --> 00:01:12,000 Speaker 1: of rivers, frozen lakes, and even your poorly cleaned aquarium 17 00:01:12,040 --> 00:01:15,440 Speaker 1: at home. When a creature is left without oxygen, it 18 00:01:15,520 --> 00:01:19,600 Speaker 1: typically experiences a build up of lactic acid, which can 19 00:01:19,600 --> 00:01:23,679 Speaker 1: turn toxic. However, these particular fish have two sets of 20 00:01:23,720 --> 00:01:27,560 Speaker 1: proteins in their muscles rather than the usual one. The 21 00:01:27,640 --> 00:01:31,320 Speaker 1: second set of proteins get activated when there isn't any 22 00:01:31,360 --> 00:01:38,120 Speaker 1: oxygen and changes lactic acid into ethanol. This biochemical adaptation 23 00:01:38,240 --> 00:01:41,520 Speaker 1: allows the fish to diffuse the substance into the water, 24 00:01:41,920 --> 00:01:47,720 Speaker 1: helping them prevent the life threatening condition lactic acidosis. Now 25 00:01:47,840 --> 00:01:53,600 Speaker 1: on fizz dot org, University of Liverpool evolutionary biologists Michael 26 00:01:53,960 --> 00:01:57,520 Speaker 1: Baron Brinck explains how these fish pull it off during 27 00:01:57,560 --> 00:02:01,000 Speaker 1: their time in oxygen free water in ice covered ponds, 28 00:02:01,040 --> 00:02:05,200 Speaker 1: which can last for several months in their Northern European habitat. 29 00:02:05,560 --> 00:02:10,240 Speaker 1: Blood alcohol concentrations in Crucian carp can reach more than 30 00:02:10,480 --> 00:02:15,720 Speaker 1: fifty milligrams per one hundred millilders, which is above the 31 00:02:15,840 --> 00:02:20,160 Speaker 1: drink and drive limit in these countries. However, this is 32 00:02:20,200 --> 00:02:24,120 Speaker 1: still a much better situation than filling up with lactic acid, 33 00:02:24,160 --> 00:02:29,320 Speaker 1: which is the metabolic end product for other vertebrates, including humans, 34 00:02:29,560 --> 00:02:33,720 Speaker 1: when devoid of oxygen. Now, this ability has turned these 35 00:02:33,760 --> 00:02:38,200 Speaker 1: species of fish into quite the Darwinian geniuses in the study. 36 00:02:38,240 --> 00:02:42,200 Speaker 1: The research explains that the evolution of the ethanol producing 37 00:02:42,280 --> 00:02:45,880 Speaker 1: pathway has not only made the goldfish one of the 38 00:02:45,960 --> 00:02:51,200 Speaker 1: most arguably resilient pets under human care, but has also 39 00:02:51,400 --> 00:02:58,200 Speaker 1: clearly provided Karasus with unique ecological benefits, allowing survival in 40 00:02:58,280 --> 00:03:03,080 Speaker 1: waters that are unin habitable for other fish, thereby evading 41 00:03:03,160 --> 00:03:08,840 Speaker 1: pisicene predation and interspecific competition. And check this out. The 42 00:03:09,000 --> 00:03:12,519 Speaker 1: mad skills of the Crucian carp don't end with alcohol production. 43 00:03:12,880 --> 00:03:17,399 Speaker 1: Historical accounts claim that they can survive several hours out 44 00:03:17,440 --> 00:03:22,480 Speaker 1: of water, or even several days with a frozen outer layer. 45 00:03:26,520 --> 00:03:29,680 Speaker 1: Today's episode was written by A. Leah Hoyt and produced 46 00:03:29,760 --> 00:03:33,280 Speaker 1: by Dylan fig. For more on this and other topics, 47 00:03:33,520 --> 00:03:46,280 Speaker 1: please visit us at house to works dot com