WEBVTT - Hair Loss: The Pits

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<v Speaker 1>Welcome to Stuff You Should Know, a production of I

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<v Speaker 1>Heart Radio. Hey, and welcome to the podcast. I'm Josh

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<v Speaker 1>Cubal Clark. There's Charles W. Mr Clean Bryant and Jerry

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<v Speaker 1>Shad O'Connor rolling rounds it out for Stuff you Should Know.

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<v Speaker 1>The hair loss edition. Remember when Sinad O'Connor and wheneveron

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<v Speaker 1>got mad because she ripped up a picture of the

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<v Speaker 1>boat to protest Catholic Church. Yeah, we talked about this

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<v Speaker 1>like a couple of weeks ago, did we Yeah? Did Yeah?

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<v Speaker 1>You go, You're going up in octave each time. It's

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<v Speaker 1>pretty much I don't remember that. We talked about a

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<v Speaker 1>saturatite live sketch where Frank Sinatra had her on and

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<v Speaker 1>the dis and stuff. Of course the great Phil Hartman

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<v Speaker 1>as chairman of the board. But Nato O'Connor wasn't losing

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<v Speaker 1>her hair. She made a conscious decision to basically stick

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<v Speaker 1>it to the establishment and say, hey, I'm shaving my head. Yeah,

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<v Speaker 1>and you know, my um, I know that we haven't

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<v Speaker 1>seen each other, but I'm I'm starting to get a

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<v Speaker 1>little thin on the crown after my hair being like

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<v Speaker 1>my only decent defining feature as a as a man

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<v Speaker 1>for many years. Sure, it's starting to thin out a

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<v Speaker 1>little on the crown that. I mean, it happens. Mine's

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<v Speaker 1>been doing that for a little while. It is distressing

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<v Speaker 1>at first, and then you just get used to it,

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<v Speaker 1>especially when it's plateaus for a while, like your mind's

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<v Speaker 1>in a plateau stage and I'm like, Okay, I can live.

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<v Speaker 1>Let's just let's hold here. Okay, holding here. Um. But yeah,

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<v Speaker 1>it is. It's a thing, for sure. It's not the

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<v Speaker 1>funniest thing in the world to realize your hair is thinning. Yeah.

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<v Speaker 1>I mean, I'm not doing anything about it, certainly because

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<v Speaker 1>I'm I don't know, I just I don't have that

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<v Speaker 1>kind of vanity of other kinds of vanity. But it's uh,

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<v Speaker 1>and I don't see it. So I was talking to

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<v Speaker 1>Null about it a movie crush and he was like,

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<v Speaker 1>you just gotta back out of every room you walk into.

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<v Speaker 1>That is good advice. That's like hair club level of advice. Yeah.

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<v Speaker 1>But I mean, I'll just you know, I've have I've

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<v Speaker 1>shaved my hair about once a year anyway, so I'm

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<v Speaker 1>fine to live that life too. Yeah, And I mean,

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<v Speaker 1>it just it happens. It's one thing that like really

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<v Speaker 1>kind of came through and researching hair loss is like,

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<v Speaker 1>there's really nothing wrong with it. It's not medically debilitating.

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<v Speaker 1>In most cases, we should say, pattern baldness the the

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<v Speaker 1>far and away the most frequent reason people lose their hair,

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<v Speaker 1>both men and women. There's nothing wrong with you. There's

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<v Speaker 1>no disease, there's no there's no problem with your metabolic functioning,

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<v Speaker 1>nothing like that. It's strictly cultural, like cultural norms and

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<v Speaker 1>preferences of beauty. That's it. That's the only thing. You're

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<v Speaker 1>just kind of involuntary violating beauty norms of your culture.

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<v Speaker 1>And if the rest of the culture can just get

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<v Speaker 1>over it, which they generally do, um, you can get

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<v Speaker 1>over it too. And that's that. And I've just dug

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<v Speaker 1>my own grave because now I'm going to have to

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<v Speaker 1>take my own medicine and get over it. I'm sure

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<v Speaker 1>all my hair is going to fall out in the

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<v Speaker 1>next hour. No it's not. But you know, we're we're

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<v Speaker 1>going to cover the types of hair loss and also

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<v Speaker 1>some remedies, and we'll get into the couple of um

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<v Speaker 1>sort of prescription remedies that they have found over the years,

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<v Speaker 1>which really hit me today more than ever, sort of

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<v Speaker 1>how cruelly it's one of them at least is which

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<v Speaker 1>is like, Hey, if you're a young and single man

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<v Speaker 1>and you're starting to lose your hair and you're worried about,

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<v Speaker 1>you know, attracting ladies, we have something for you, and

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<v Speaker 1>and it might give you a rectile dysfunction and you

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<v Speaker 1>might not be interested in sex, but you'll have your

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<v Speaker 1>hair back. You're gonna have some hair, baby, Like, man,

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<v Speaker 1>what a what a weird cruel trade off? I know,

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<v Speaker 1>chemistry giveth in, chemistry take it away. So I guess

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<v Speaker 1>that was a spoiler, but I think most people know

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<v Speaker 1>that and know what we're talking about. Yeah, we'll get

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<v Speaker 1>into that in a little while. But first I think

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<v Speaker 1>we should talk about if we're talking about hair loss,

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<v Speaker 1>which we are talking about hair loss, we should talk

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<v Speaker 1>about how hair grows in the first place, because it

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<v Speaker 1>is just part of the natural order of things that

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<v Speaker 1>your hair falls out. There's like three stages of hair

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<v Speaker 1>growth that applies not just to human hair but also

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<v Speaker 1>to animal for two, because don't forget you are an

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<v Speaker 1>animal to human um and so we have the same

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<v Speaker 1>three stages of growth, um, shrinkage, and then resting. Uh.

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<v Speaker 1>That's basically the broad strokes of them, but it's a

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<v Speaker 1>little more interesting in the details. Yeah, I mean I

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<v Speaker 1>kind of linked um. I kind of thought of it

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<v Speaker 1>as little gremlins under your scalp, little knitting gremlins. And

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<v Speaker 1>when you're in that anagin phase A N A G

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<v Speaker 1>E N, that is when your hair is growing and

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<v Speaker 1>cells are forming a little protein root at the base

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<v Speaker 1>of every little hair follicle that produces hair, and that's

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<v Speaker 1>that's when those gremlins are down there knitting the hair.

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<v Speaker 1>And they're continuously knitting, like you know, when hair is

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<v Speaker 1>growing growing out of a follicle. They're just they're hard

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<v Speaker 1>at work, and it just keeps going and keeps going,

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<v Speaker 1>and you're cutting it and they they keep sending it

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<v Speaker 1>through that shoot and everything's great. Yeah, And like that,

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<v Speaker 1>those gremlins basically form an organ. Each of your hair

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<v Speaker 1>follicles is basically an organ. There's a lot of stuff

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<v Speaker 1>going on down there's a lot of a lot of

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<v Speaker 1>growth factors and proteins working, and cells being converted from

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<v Speaker 1>stem cells into epithelial cells and um. The um follicle

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<v Speaker 1>is lined with muscles that are pushing the hair up

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<v Speaker 1>as new new hair cells are formed. It's pretty interesting stuff.

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<v Speaker 1>And this phase that you're talking about where the gremlins

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<v Speaker 1>are really working in overdrive is called the Anergin phase

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<v Speaker 1>and at lasts anywhere from two to six years for

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<v Speaker 1>your hair, and you get haircut so often we used

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<v Speaker 1>to before the pandemic that, um, you don't think like

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<v Speaker 1>a single hair that you're getting cut like every you know,

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<v Speaker 1>six or eight weeks. However often you go in, um

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<v Speaker 1>it's trying to grow out for like six straight years,

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<v Speaker 1>but you keep cutting it. It must be very frustrating

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<v Speaker 1>for the hair follicle must be. The next phase is

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<v Speaker 1>basically grimlins go on vacation. This is the I guess

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<v Speaker 1>the catagin phase, and at some point this little protein

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<v Speaker 1>cellsis matrix at the root of the hair follicle is

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<v Speaker 1>gonna run dry. The follicle stops growing new hair cells,

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<v Speaker 1>and those grimlins are taking some time off and that

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<v Speaker 1>hair strand though it's not like that hair falls out immediately,

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<v Speaker 1>it still is getting kind of pushed through and you

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<v Speaker 1>think it's growing almost said it's growing. It's not. It's

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<v Speaker 1>not growing anymore, but it's just being kind of pushed

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<v Speaker 1>through to the very end. And finally it just pop

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<v Speaker 1>goes through and that's it for that hair and that follicle, right,

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<v Speaker 1>and so that that happens, I didn't even given points time.

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<v Speaker 1>I think there's like, oh I saw the percentage. I

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<v Speaker 1>can't remember right now, but there's like somewhere I think

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<v Speaker 1>maybe six percent of your hair is in the cattagin

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<v Speaker 1>phase at any given point in time, and you lose

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<v Speaker 1>something like fifty to a hundred hairs a day off

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<v Speaker 1>of your head totally normal. Those are just hairs that

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<v Speaker 1>have reached that cattage and phase and finally got pushed

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<v Speaker 1>all the way out. And I guess between the hair

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<v Speaker 1>we lose and the dead skin cells that we slough

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<v Speaker 1>off of our our epidermist every day, if you could

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<v Speaker 1>manage to sweep it all together into a little pile,

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<v Speaker 1>it way about one point five grams every day, hair

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<v Speaker 1>and hair and dead skin you're losing. But imagine if

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<v Speaker 1>you could like you know, collect that and really get

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<v Speaker 1>a pretty good pile going after a few months. You know, well,

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<v Speaker 1>I think there are some people you might do stuff

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<v Speaker 1>like that. Sure, there are, there's there are definitely there's

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<v Speaker 1>somebody who does everything, and there's probably some there's somebody

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<v Speaker 1>who's turned on by the idea of that as well.

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<v Speaker 1>Out there too, it cuts off to you guys, this

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<v Speaker 1>skin cell collectors and the dead skin cell um kink kinks. Yeah,

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<v Speaker 1>what about Yeah, for sure, we don't judge. What about

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<v Speaker 1>the last as long as you're not harming anybody, right,

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<v Speaker 1>that's right. What is the last phase? Because there's a

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<v Speaker 1>third phase two that this is really like the resting

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<v Speaker 1>phase where it's kind of regrouping, Like the gremlins are

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<v Speaker 1>laying around there, spent, they're exhausted, they're catching their breath basically,

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<v Speaker 1>that's the I mean, I think their vacation is kind

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<v Speaker 1>of winding down at this point during the intelligent phase,

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<v Speaker 1>and that, like you said, that's dormant. The follicle is

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<v Speaker 1>sort of resting. Those gremlins are resting. Uh, they're forming

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<v Speaker 1>and they're getting those needles sharp again to those knitting

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<v Speaker 1>needles sharp, which in the body means they're forming a

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<v Speaker 1>new protein matrix and they're getting ready to punch the

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<v Speaker 1>clock and go back to work. And that dormancy is

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<v Speaker 1>a few weeks. They get a few weeks maybe a

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<v Speaker 1>few months off before it kicks off in that anagin

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<v Speaker 1>phase all over again. Yeah, what's interesting, um, is you know,

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<v Speaker 1>hair loss has been viewed as basically cosmetic. Like you know,

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<v Speaker 1>almost all cultures. I couldn't find any that seemed to

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<v Speaker 1>like really have no opinions about it. It seems like

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<v Speaker 1>all cultures view hair loss as sucking, right, But in

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<v Speaker 1>the West it's viewed as a cosmetic problem. So there

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<v Speaker 1>hasn't been like a ton of research into it, certainly

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<v Speaker 1>very little government funded research into it. Um. I am too,

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<v Speaker 1>But it was explained in something I read that it's

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<v Speaker 1>it's just cosmetic. It's like ts that happens, get over it.

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<v Speaker 1>But in the in um the East, in Asian countries

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<v Speaker 1>in particular, it's a much less frequent occurrence, but it's

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<v Speaker 1>picking up UM and they think because of a more hectic,

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<v Speaker 1>unhealthy lifestyle, more Asian men and like China career in

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<v Speaker 1>Japan are losing their hair, especially in a younger age,

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<v Speaker 1>and that is a big deal in those cultures, and

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<v Speaker 1>so there's a lot more government funding that's being put

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<v Speaker 1>into it in the last decade or so. But the

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<v Speaker 1>interesting thing that stuck out to me is that we

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<v Speaker 1>are learning about how hair grows by doing research on

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<v Speaker 1>how to prevent hair loss. And we know less about

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<v Speaker 1>how hair grows than I realized. So basically everything we

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<v Speaker 1>said is a pretty good understanding, but there's still a

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<v Speaker 1>lot of different components to the whole thing that science

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<v Speaker 1>doesn't fully understand that we probably will have a better

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<v Speaker 1>grasp on than in the next time to twenty years

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<v Speaker 1>from hair loss research. Yeah, I think it's Asian heritage

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<v Speaker 1>and African heritage, and uh, it seems like there was

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<v Speaker 1>one more Native American Native American, right, they think they

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<v Speaker 1>suffer hair loss less frequently. Yeah, from what I saw,

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<v Speaker 1>it's Caucasian. White um and African American tend to be

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<v Speaker 1>the two dominant groups for hair loss, but far and

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<v Speaker 1>away white men lose their hair more than any other group. Well,

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<v Speaker 1>that's why I was surprised that wasn't more research, even

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<v Speaker 1>though it's cosmetic, because it's just largely white man. I

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<v Speaker 1>was like, well, we need to get on this right now, gentlemen.

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<v Speaker 1>It's happening to white man. Do I have to repeat myself? Yeah,

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<v Speaker 1>that's a great point. Should we Uh let's take a

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<v Speaker 1>break here, and well is that good with you? Yeah? Yeah,

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<v Speaker 1>I think that's a great idea. Okay, I know that

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<v Speaker 1>it's funny we get emails where people want us to

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<v Speaker 1>come to blows over taking breaks. I know, do you

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<v Speaker 1>guys ever get mad? Not want to take a break?

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<v Speaker 1>Like not really? Huh? Do you? All? Right? Well, we

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<v Speaker 1>will take a break then, since Josh agreed, and only

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<v Speaker 1>because he agreed, and we'll come back and talk about

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<v Speaker 1>some of the less common causes of hair loss right

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<v Speaker 1>after this shot. Okay, So um, Chuck, you've heard the

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<v Speaker 1>word alopecia before, right, yeah, for sure. Anytime I've heard alopecia,

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<v Speaker 1>it's a it's in reference to the condition that I

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<v Speaker 1>didn't realize, but it makes sense as an autoimmune disorder

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<v Speaker 1>where you have no hair whatsoever, no eyebrows, no head hair,

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<v Speaker 1>no hair on your legs anywhere. Um. But it turns

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<v Speaker 1>out that all hair loss scientifically speaking of any kind,

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<v Speaker 1>including you know, thinning of the hair that you and

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<v Speaker 1>I have, is considered alopecia. And alopecia actually comes from

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<v Speaker 1>the Greek for um, the Greek word fox, which makes

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<v Speaker 1>tons of sense. Right, yeah, I thought that was kind

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<v Speaker 1>of interesting. Um. Supposedly, in ancient Greece there were some

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<v Speaker 1>foxes that could get a type of mange that caused

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<v Speaker 1>him to lose hair and big patches, and so they

0:12:52.040 --> 0:12:54.800
<v Speaker 1>just that's where the word came from. Uh. I'm not

0:12:54.840 --> 0:12:57.000
<v Speaker 1>sure how it got transferred to humans, but you know,

0:12:57.040 --> 0:12:59.199
<v Speaker 1>the ancient Greeks marched to the beat of their own drummer.

0:12:59.520 --> 0:13:03.119
<v Speaker 1>I think somebody was being droll and said, oh, that's

0:13:03.160 --> 0:13:06.880
<v Speaker 1>that's fox. Like really, that's what I'm getting from. And

0:13:06.920 --> 0:13:09.560
<v Speaker 1>I know it was it was Hippocrates that popularized it.

0:13:09.720 --> 0:13:15.520
<v Speaker 1>So that guy, Yeah, that guy, that guy, what are

0:13:15.559 --> 0:13:18.760
<v Speaker 1>you doing what we do in the shadows? Yeah, but

0:13:18.800 --> 0:13:22.719
<v Speaker 1>you gotta go that deafing guy. Uh, I know you're

0:13:22.720 --> 0:13:26.079
<v Speaker 1>rewatching that right. Yes, it's so good. It's a good time,

0:13:26.120 --> 0:13:29.520
<v Speaker 1>isn't it. Yes, it is. Um. So there are few.

0:13:29.920 --> 0:13:32.000
<v Speaker 1>Like you said, it means any kind of hair loss,

0:13:32.000 --> 0:13:35.760
<v Speaker 1>so obviously there are a few different kinds. But alopecia ariata,

0:13:36.040 --> 0:13:39.920
<v Speaker 1>that is the autoimmune condition specifically that's gonna fool your

0:13:39.920 --> 0:13:42.920
<v Speaker 1>body into attacking its own healthy cells because it's an

0:13:42.920 --> 0:13:46.800
<v Speaker 1>autoimmune condition, and especially the hair follicles in this case.

0:13:47.360 --> 0:13:50.559
<v Speaker 1>And if you have alopecia ariata, you're gonna lose hair

0:13:50.679 --> 0:13:53.840
<v Speaker 1>and patches. Um. If you lose all the hair on

0:13:53.880 --> 0:13:57.880
<v Speaker 1>your scalp, that's alopecia total us. And then I think

0:13:57.880 --> 0:13:59.880
<v Speaker 1>what you were talking about. There is the most of

0:14:00.040 --> 0:14:03.079
<v Speaker 1>air condition where you know, someone doesn't have any hair

0:14:03.080 --> 0:14:05.360
<v Speaker 1>on their body at all. I can't remember the actor's name.

0:14:05.720 --> 0:14:09.120
<v Speaker 1>Who Hank from Barry. I don't know who that is

0:14:09.320 --> 0:14:15.040
<v Speaker 1>from Barry Barry. Yeah, remember Hank the gangster? You know,

0:14:15.160 --> 0:14:17.240
<v Speaker 1>I didn't only watched a little bit of the first

0:14:17.240 --> 0:14:19.800
<v Speaker 1>season of Barry, which one was Hank. Hank was the

0:14:20.080 --> 0:14:26.680
<v Speaker 1>super lovable, like murderous psychopath who is like the I

0:14:26.680 --> 0:14:29.960
<v Speaker 1>can't remember if they're Ukrainian. I think they're Ukrainian right there.

0:14:30.000 --> 0:14:32.400
<v Speaker 1>It doesn't need like work for the Ukrainian mob. I

0:14:32.400 --> 0:14:34.200
<v Speaker 1>don't know, man, I didn't get far enough into Berry

0:14:34.320 --> 0:14:37.240
<v Speaker 1>and you met Hank. I promise, all right, Just I

0:14:37.240 --> 0:14:38.880
<v Speaker 1>don't know if that's the actor I'm talking about, but

0:14:38.920 --> 0:14:44.760
<v Speaker 1>there is a famous actor who suffers from alopecia, uh universalice.

0:14:44.800 --> 0:14:46.600
<v Speaker 1>And that's the one where you don't have any hair

0:14:46.600 --> 0:14:50.760
<v Speaker 1>on your body. Right um. But again, any like any

0:14:50.840 --> 0:14:54.280
<v Speaker 1>kind of hair loss medically speaking, is referred to as alopecia.

0:14:54.680 --> 0:14:59.440
<v Speaker 1>That is correct, and so um alopecia, like I was saying,

0:14:59.440 --> 0:15:02.480
<v Speaker 1>it's a it's a autoimmune disorder and they're working on it,

0:15:02.520 --> 0:15:05.800
<v Speaker 1>but it's basically they don't really have much of a

0:15:05.880 --> 0:15:10.440
<v Speaker 1>cure for right now. Um. And the same goes from

0:15:10.480 --> 0:15:13.720
<v Speaker 1>what I understand for another condition that has to do

0:15:13.760 --> 0:15:18.720
<v Speaker 1>with hair loss called telligent fluvium um. And fortunately for

0:15:18.760 --> 0:15:22.240
<v Speaker 1>people who have telligent fluvium that hair loss is kind

0:15:22.240 --> 0:15:26.280
<v Speaker 1>of temporary. But really interestingly, it can come as the

0:15:26.320 --> 0:15:32.280
<v Speaker 1>result of like a a profound emotional hardship. Yeah, it

0:15:32.280 --> 0:15:35.960
<v Speaker 1>could be a life trauma or something. If you're some

0:15:36.200 --> 0:15:38.320
<v Speaker 1>suffering from any kind of traumatic event, that could be

0:15:38.360 --> 0:15:42.760
<v Speaker 1>the case. And this is when basically the gremlins are

0:15:43.560 --> 0:15:46.760
<v Speaker 1>is uh, they're on like Aerosmith, they're on permanent vacation

0:15:47.680 --> 0:15:50.880
<v Speaker 1>and it is stuck in the dormant phase for basically

0:15:51.120 --> 0:15:53.640
<v Speaker 1>longer I guess semi permanent vacation because like you said,

0:15:53.640 --> 0:15:56.720
<v Speaker 1>it is temporary, but it's stuck in that phase for

0:15:56.800 --> 0:16:00.960
<v Speaker 1>longer than usual. And you know, it could be anything.

0:16:01.000 --> 0:16:03.920
<v Speaker 1>You could have a big surgery that was stressful, or

0:16:04.320 --> 0:16:07.400
<v Speaker 1>given birth or any sort of I mean, there could

0:16:07.400 --> 0:16:10.000
<v Speaker 1>be just a traumatic emotional event in your life that

0:16:10.040 --> 0:16:12.480
<v Speaker 1>caused that kicks us off. Yeah, and when your hair

0:16:12.760 --> 0:16:16.480
<v Speaker 1>is in a normal UM cycle of growth like the

0:16:16.720 --> 0:16:20.239
<v Speaker 1>Like I said, there's constantly hair that's in the the

0:16:20.240 --> 0:16:23.320
<v Speaker 1>the cattagen phase, that resting phase of the intelligent phase,

0:16:23.320 --> 0:16:26.240
<v Speaker 1>of the super resting phase of the re regrouping phase

0:16:26.280 --> 0:16:28.960
<v Speaker 1>I guess UM. And then more most of them are

0:16:28.960 --> 0:16:33.080
<v Speaker 1>in the engine phase. UM. With telligent effluvium, you've got

0:16:33.080 --> 0:16:35.520
<v Speaker 1>the same cycle going on. It's just they stay in

0:16:35.560 --> 0:16:39.640
<v Speaker 1>that cattagen phase longer, so there's less hair coming out

0:16:39.640 --> 0:16:41.840
<v Speaker 1>at any given point in time or growing out at

0:16:41.840 --> 0:16:44.480
<v Speaker 1>any given point in time, So it seems thinner, but

0:16:44.520 --> 0:16:47.840
<v Speaker 1>again it's just temporary. Once you your body kind of

0:16:48.120 --> 0:16:53.400
<v Speaker 1>goes back to its previous normal or baseline emotional state,

0:16:53.800 --> 0:16:56.560
<v Speaker 1>it can it can be fine. UM. This can also

0:16:56.640 --> 0:17:01.640
<v Speaker 1>come about from a thyroid deficiency or iron deficiency, and

0:17:01.760 --> 0:17:05.800
<v Speaker 1>both of those things are involved UM. Thyroid growth hormone

0:17:05.920 --> 0:17:08.960
<v Speaker 1>and iron are involved in cell division. Remember you talked

0:17:09.000 --> 0:17:11.800
<v Speaker 1>about the gremlins working over time. Well, one of the

0:17:11.840 --> 0:17:17.320
<v Speaker 1>things they're doing is UM growing cells, dividing cells very

0:17:17.359 --> 0:17:20.440
<v Speaker 1>quickly to turn them into hair that's growing. And so

0:17:20.480 --> 0:17:24.920
<v Speaker 1>if those two things aren't feeding this hair growth, UM,

0:17:25.000 --> 0:17:28.959
<v Speaker 1>that can cause this telligent effluvium too. That's right. Uh.

0:17:29.000 --> 0:17:32.400
<v Speaker 1>And then of course there's chemotherapy. Anyone who's ever had

0:17:33.040 --> 0:17:37.240
<v Speaker 1>a family member or themselves been through the really powerful

0:17:37.280 --> 0:17:40.520
<v Speaker 1>medications you have to endure with chemotherapy that can also

0:17:40.600 --> 0:17:44.560
<v Speaker 1>lead to temporary hair loss UM and you know it's

0:17:44.600 --> 0:17:48.639
<v Speaker 1>it's targeting cancer cells, but it's also targeting hair cells

0:17:48.680 --> 0:17:51.600
<v Speaker 1>because what they're trying to do is stop the fast

0:17:51.600 --> 0:17:54.640
<v Speaker 1>growing cells, and the hair cells are among those. So

0:17:55.040 --> 0:17:58.000
<v Speaker 1>it is one of the unfortunate side effects of chemotherapy,

0:17:58.040 --> 0:18:01.400
<v Speaker 1>but again temporary. And you know, our our heart goes

0:18:01.400 --> 0:18:03.560
<v Speaker 1>out to anyone that's had to go through chemotherapy. It's

0:18:03.600 --> 0:18:06.159
<v Speaker 1>really rough and most of us have probably seen it

0:18:06.640 --> 0:18:09.800
<v Speaker 1>through someone that they know pretty closely. And hair loss

0:18:09.840 --> 0:18:13.280
<v Speaker 1>can be a big, big, big part of it. UM.

0:18:13.359 --> 0:18:17.359
<v Speaker 1>And then there's u androw genetic alopecia, And this is

0:18:17.400 --> 0:18:20.639
<v Speaker 1>the one that is far and away the type of

0:18:21.240 --> 0:18:25.520
<v Speaker 1>hair loss that that most people suffer, both men and women.

0:18:25.640 --> 0:18:28.399
<v Speaker 1>It's called male pattern baldness is another word for it,

0:18:28.640 --> 0:18:33.000
<v Speaker 1>but there's also pattern baldness for women as well. Um.

0:18:33.040 --> 0:18:35.480
<v Speaker 1>It's just that again, if you're a white man, the

0:18:35.560 --> 0:18:39.720
<v Speaker 1>chances are that you have some form of or some

0:18:39.880 --> 0:18:44.320
<v Speaker 1>degree i should say of Androw genetic alopecia. Yeah, I

0:18:44.320 --> 0:18:49.199
<v Speaker 1>think it's about of anyone who suffers from pattern pattern

0:18:49.200 --> 0:18:53.080
<v Speaker 1>baldness are women. But it's not talked about as much,

0:18:53.400 --> 0:18:55.880
<v Speaker 1>um I think, And it's it's not like it's only

0:18:55.920 --> 0:18:59.040
<v Speaker 1>ten percent. I meant is substantial, but it's usually not

0:18:59.080 --> 0:19:02.440
<v Speaker 1>as severe. So and it happens in a different way

0:19:02.480 --> 0:19:05.240
<v Speaker 1>which we'll get to. But um, so it's it may

0:19:05.240 --> 0:19:08.080
<v Speaker 1>not be as noticeable to others. And I think and

0:19:08.200 --> 0:19:11.320
<v Speaker 1>that just with you know, probably male biases. The reason

0:19:11.359 --> 0:19:14.119
<v Speaker 1>why you don't hear pattern baldm has talked about for

0:19:14.160 --> 0:19:16.840
<v Speaker 1>women as much I would. I think you're exactly right

0:19:16.880 --> 0:19:19.840
<v Speaker 1>for sure. Plus also, I mean the basis of it

0:19:19.880 --> 0:19:22.840
<v Speaker 1>too seems to have to do with male sex hormones,

0:19:22.960 --> 0:19:26.720
<v Speaker 1>So it seems like, you know, like it it it's

0:19:26.720 --> 0:19:30.840
<v Speaker 1>more directed towards males in general as well. Well yeah,

0:19:30.920 --> 0:19:34.240
<v Speaker 1>so what's what's the deal with that? So androw genetic

0:19:34.600 --> 0:19:38.720
<v Speaker 1>um refers to the Greek root word ander for man um,

0:19:38.760 --> 0:19:41.120
<v Speaker 1>and what it's really talking about our androgen's, which are

0:19:41.680 --> 0:19:45.440
<v Speaker 1>um sex hormones, and in particular, one of the culprits

0:19:45.520 --> 0:19:50.720
<v Speaker 1>is a form of testosterone called dihydro testosterone, which is

0:19:50.720 --> 0:19:56.119
<v Speaker 1>like testosterone on testosterone basically, UM, when testosterone comes in

0:19:56.200 --> 0:20:01.320
<v Speaker 1>contact with something called five alpha reductase, which is uh

0:20:01.600 --> 0:20:04.720
<v Speaker 1>some sort of enzyme that you can find a muscle tissue,

0:20:05.240 --> 0:20:09.480
<v Speaker 1>it gets converted into this die hydro testosterone d H TEA.

0:20:09.640 --> 0:20:11.159
<v Speaker 1>I feel like we talked about this. Was it in

0:20:11.200 --> 0:20:15.360
<v Speaker 1>the male puberty? Maybe probably I would guess either that

0:20:15.560 --> 0:20:20.240
<v Speaker 1>or ballpoint pens one of this too. You know, it's

0:20:20.240 --> 0:20:22.000
<v Speaker 1>funny as you're saying that, I was trying to think

0:20:22.040 --> 0:20:24.000
<v Speaker 1>of a funny one, and then there you had it

0:20:24.080 --> 0:20:27.440
<v Speaker 1>under control. Nice. Thanks, one of us always has it

0:20:27.560 --> 0:20:32.080
<v Speaker 1>under control. And if then we're in big trouble, Yeah,

0:20:32.359 --> 0:20:34.840
<v Speaker 1>that's when it's time to go away. So this d

0:20:35.000 --> 0:20:37.280
<v Speaker 1>HT stuff, this is this is the this is the

0:20:37.320 --> 0:20:42.000
<v Speaker 1>weird thing. Like, there is a general understanding that die

0:20:42.040 --> 0:20:45.960
<v Speaker 1>hydro testosterone has to do with pattern baldness, whether in

0:20:46.080 --> 0:20:53.440
<v Speaker 1>males or females, but it um, it's not exactly understood

0:20:53.880 --> 0:20:57.760
<v Speaker 1>how it produces pattern baldness. We just know and have

0:20:57.880 --> 0:21:01.520
<v Speaker 1>known since I believe the late nineteen forty. These um

0:21:01.560 --> 0:21:04.280
<v Speaker 1>that if you have pattern baldness, you have a higher

0:21:04.320 --> 0:21:07.520
<v Speaker 1>concentration of d HT and your scalp than people who

0:21:07.600 --> 0:21:10.560
<v Speaker 1>don't have pattern baldness. So that seems like a pretty

0:21:10.560 --> 0:21:13.440
<v Speaker 1>big clue. Yeah. And the reason it happens to both

0:21:13.440 --> 0:21:18.400
<v Speaker 1>men and women is because both men and women produce testosterone. Um.

0:21:18.440 --> 0:21:21.520
<v Speaker 1>I think most people know this, but if you didn't

0:21:21.520 --> 0:21:23.959
<v Speaker 1>pay attention in biology class, you may not know that

0:21:24.320 --> 0:21:28.560
<v Speaker 1>women produce testosterone in their ovaries. Uh, and just not

0:21:28.600 --> 0:21:30.720
<v Speaker 1>as much as men obviously, so they have lower levels

0:21:30.760 --> 0:21:34.640
<v Speaker 1>of testosterone, lower levels of d HT as a result.

0:21:35.119 --> 0:21:38.119
<v Speaker 1>And so that's why a there in um, they're in

0:21:38.160 --> 0:21:41.280
<v Speaker 1>the minority as far as suffering from pattern baldness and

0:21:41.280 --> 0:21:46.400
<v Speaker 1>why it happens to a lesser degree when it does happen, right, Um,

0:21:46.400 --> 0:21:50.359
<v Speaker 1>But it's a really weird paradox that die hydro testosterone

0:21:50.400 --> 0:21:55.840
<v Speaker 1>would um produce pattern baldness because we actually need it

0:21:55.880 --> 0:22:00.439
<v Speaker 1>to produce pubic hair and armpit hair. Um, So you

0:22:00.440 --> 0:22:02.399
<v Speaker 1>wouldn't have either of those. If you have a d

0:22:02.600 --> 0:22:05.760
<v Speaker 1>HT deficiency or a testosterone deficiency, you have less pubic

0:22:05.800 --> 0:22:09.119
<v Speaker 1>hair armpit hair, and you don't develop those types of

0:22:09.160 --> 0:22:11.760
<v Speaker 1>hair until you start to develop testosterone and then in

0:22:11.840 --> 0:22:15.480
<v Speaker 1>turn d HT after you reach puberty. Head hair has

0:22:15.520 --> 0:22:18.880
<v Speaker 1>nothing to do with d h T, And yet at

0:22:18.920 --> 0:22:21.919
<v Speaker 1>some point later in life, d HT for some reason

0:22:21.960 --> 0:22:25.080
<v Speaker 1>starts to accumulate in the in the scalps of a

0:22:25.080 --> 0:22:28.440
<v Speaker 1>lot of people, and it actually causes hair loss rather

0:22:28.480 --> 0:22:31.280
<v Speaker 1>than hair growth, which at the very least you'd think,

0:22:32.440 --> 0:22:34.679
<v Speaker 1>you know, what if what if it converted our hair

0:22:34.720 --> 0:22:37.199
<v Speaker 1>into pubic hair later in life, that would be hilarious,

0:22:38.640 --> 0:22:42.200
<v Speaker 1>especially in the areas in the same pattern that you bawl.

0:22:42.359 --> 0:22:46.000
<v Speaker 1>But if that just got replaced with pubic hair, hey,

0:22:45.880 --> 0:22:48.240
<v Speaker 1>that would be pretty sweet. It'd be the nineteen seventies

0:22:48.280 --> 0:22:50.120
<v Speaker 1>all over again. It would be It would be awesome.

0:22:50.280 --> 0:22:52.879
<v Speaker 1>You wouldn't have to be Mike Brady getting that that

0:22:53.720 --> 0:22:56.919
<v Speaker 1>tight curl going. I love that, man. I remember that smell. Man.

0:22:56.960 --> 0:22:59.000
<v Speaker 1>I don't know if I don't know if your mom

0:22:59.040 --> 0:23:01.440
<v Speaker 1>ever did that, but my mom um would get the perm,

0:23:01.680 --> 0:23:04.520
<v Speaker 1>the at home perm every now and then for a

0:23:04.560 --> 0:23:07.520
<v Speaker 1>few years in the seventies, and that smell for some reason,

0:23:07.520 --> 0:23:09.320
<v Speaker 1>you know how you just tired to tie these things

0:23:09.359 --> 0:23:12.160
<v Speaker 1>together in your brain. She was doing it one night

0:23:12.240 --> 0:23:15.480
<v Speaker 1>while the Circus of the Stars was on. So to

0:23:15.560 --> 0:23:17.399
<v Speaker 1>this day I can't think of the Circus of the

0:23:17.400 --> 0:23:21.520
<v Speaker 1>Stars without thinking of that smell of Yeah, I guess

0:23:21.560 --> 0:23:26.920
<v Speaker 1>it's better than elephant poop. Sure, I always I associate, Well,

0:23:26.960 --> 0:23:30.280
<v Speaker 1>the smell of elephant poop is not pleasant. There's the perm.

0:23:30.720 --> 0:23:32.920
<v Speaker 1>I know it's I think the perms probably worse than

0:23:32.920 --> 0:23:35.640
<v Speaker 1>elephant poop. At least elephant poop is like an organic smell.

0:23:35.720 --> 0:23:39.280
<v Speaker 1>This is just straight chemical nightmare, you know. Um, I

0:23:39.320 --> 0:23:45.520
<v Speaker 1>always associate Pizza Hut home delivery with solid Gold because

0:23:45.560 --> 0:23:47.760
<v Speaker 1>my parents would, um, if they were going out on

0:23:47.760 --> 0:23:49.919
<v Speaker 1>a Saturday night, you know, they'd be getting ready and

0:23:49.920 --> 0:23:52.840
<v Speaker 1>they just ordered pizza Hut or something for us to eat,

0:23:52.960 --> 0:23:55.199
<v Speaker 1>and we would sit there and watch Solid Gold and

0:23:55.280 --> 0:23:58.520
<v Speaker 1>eat pizza Hut. So funny, man, I always thought, even

0:23:58.560 --> 0:24:00.600
<v Speaker 1>as a kid too, I was funny. They called it

0:24:00.640 --> 0:24:04.240
<v Speaker 1>a perm because it wasn't permanent, and I learned it

0:24:04.280 --> 0:24:07.600
<v Speaker 1>stood for permanent. And I remember being like eleven and

0:24:07.640 --> 0:24:11.359
<v Speaker 1>saying like they should call it a temp and yeah,

0:24:11.440 --> 0:24:15.320
<v Speaker 1>then getting beat up on the playground while we were

0:24:15.320 --> 0:24:18.359
<v Speaker 1>all standing around talking about firms or yeah, or being

0:24:18.400 --> 0:24:22.800
<v Speaker 1>the most popular kid at your experimental middle school high school. Perhaps.

0:24:23.359 --> 0:24:26.440
<v Speaker 1>Um So back to d h D, we should point

0:24:26.480 --> 0:24:30.640
<v Speaker 1>out that that was discovered in uh this ananomous named

0:24:30.680 --> 0:24:34.280
<v Speaker 1>James Hamilton's discovered the role or I guess uncovered the

0:24:34.359 --> 0:24:36.280
<v Speaker 1>role of d h D in pattern baldness. So that

0:24:36.320 --> 0:24:39.040
<v Speaker 1>was a big step forward as far as kind of

0:24:39.080 --> 0:24:42.560
<v Speaker 1>getting a semi understanding. Yeah, so what they think happens,

0:24:42.720 --> 0:24:47.480
<v Speaker 1>think we still understand it is that um testosterone comes

0:24:47.480 --> 0:24:52.800
<v Speaker 1>in contact with that five alpha reductees in those muscles

0:24:52.880 --> 0:24:55.800
<v Speaker 1>that pushed the hair up in the follicles, and that

0:24:56.040 --> 0:24:59.560
<v Speaker 1>in those follicles it's converted to d h T and

0:24:59.600 --> 0:25:03.280
<v Speaker 1>then for some reason, somehow, some way, the d HT

0:25:04.080 --> 0:25:09.439
<v Speaker 1>shrinks the hair follicle, and the hair follicle stays in

0:25:09.800 --> 0:25:16.040
<v Speaker 1>the anagen. The growth phase far less frequently produces thinner,

0:25:17.119 --> 0:25:20.880
<v Speaker 1>less robust hair, and then eventually just stops functioning at all.

0:25:21.440 --> 0:25:24.800
<v Speaker 1>And that's it. Yeah, they say, enough of this d

0:25:25.040 --> 0:25:28.160
<v Speaker 1>H stuff. I used to enjoy this neighborhood, and now

0:25:28.280 --> 0:25:30.159
<v Speaker 1>the d h T came along and I don't like it.

0:25:30.200 --> 0:25:32.439
<v Speaker 1>He always wants to fight and push people around and

0:25:32.480 --> 0:25:35.119
<v Speaker 1>talk about how much he can lift, and uh, you

0:25:35.200 --> 0:25:38.160
<v Speaker 1>want to come to his cross fit class because he'll

0:25:38.200 --> 0:25:41.080
<v Speaker 1>show you what real working out is all about. Yeah,

0:25:41.119 --> 0:25:43.000
<v Speaker 1>and his dad's an attorney and he'll sue you for

0:25:43.040 --> 0:25:45.320
<v Speaker 1>all the money you've got. Yeah, exactly. It's just a

0:25:45.480 --> 0:25:49.760
<v Speaker 1>just a general pain. So if you recognize the name,

0:25:49.840 --> 0:25:52.280
<v Speaker 1>if you suffer from pattern baldness, you probably have done

0:25:52.320 --> 0:25:54.760
<v Speaker 1>a lot of research and the name Hamilton's might seem

0:25:54.800 --> 0:25:58.840
<v Speaker 1>familiar because he is also one of the cats who

0:25:59.119 --> 0:26:03.679
<v Speaker 1>identify first those stages of the of the pattern balding.

0:26:03.760 --> 0:26:07.479
<v Speaker 1>And it's called the Hamilton's Norwood scale. So you've probably

0:26:07.480 --> 0:26:11.480
<v Speaker 1>heard the Hamilton's Norwood scale. That is when huh Yeah,

0:26:11.520 --> 0:26:13.720
<v Speaker 1>I mean I think if you start to um, if

0:26:13.760 --> 0:26:16.720
<v Speaker 1>you have an internet connection and you start to lose

0:26:16.760 --> 0:26:19.520
<v Speaker 1>your hair, you probably find out pretty quickly. But it's

0:26:19.560 --> 0:26:23.760
<v Speaker 1>not just like something people talk about unless it's you know,

0:26:23.840 --> 0:26:26.359
<v Speaker 1>people that are all suffering hair loss and they're all

0:26:26.359 --> 0:26:28.439
<v Speaker 1>talking about where they are on the scale. It's not

0:26:28.480 --> 0:26:32.120
<v Speaker 1>like the Bristol stool scale, which everybody knows about. Where

0:26:32.119 --> 0:26:37.240
<v Speaker 1>the was it the Scoville hot pepper thing? Yeah, not

0:26:37.400 --> 0:26:43.920
<v Speaker 1>commonplace like that, but the common uh pattern that emerged

0:26:44.160 --> 0:26:47.280
<v Speaker 1>that was recognized by Hamilton's. And I don't even know

0:26:47.320 --> 0:26:51.280
<v Speaker 1>who was Norwood? Do you know? Uh? Norwood was Mr

0:26:51.320 --> 0:26:56.440
<v Speaker 1>Glenn Norwould. I can't even make this joke. Anywhere to

0:26:56.560 --> 0:27:00.640
<v Speaker 1>stop here, all right, and that seria on out yea.

0:27:01.640 --> 0:27:06.240
<v Speaker 1>So uh. The common h pattern is you get an

0:27:06.440 --> 0:27:10.040
<v Speaker 1>M sort of at the front of your hairline, at

0:27:10.040 --> 0:27:14.040
<v Speaker 1>your forehead. The upper corners start to recede, and you

0:27:14.119 --> 0:27:16.840
<v Speaker 1>might hear it call a receding hairline, and it sort

0:27:16.880 --> 0:27:19.720
<v Speaker 1>of looks like the letter M because like the little

0:27:19.760 --> 0:27:22.280
<v Speaker 1>Eddie Monster, it kind of comes to a point and

0:27:22.280 --> 0:27:24.520
<v Speaker 1>then goes in on the sides. And that's step one.

0:27:24.880 --> 0:27:28.960
<v Speaker 1>I think it's a very handsome look M hairline. Receding

0:27:29.000 --> 0:27:32.919
<v Speaker 1>hairline is I think it's sharp. No, I do, and

0:27:33.000 --> 0:27:34.920
<v Speaker 1>I haven't you know, mine went straight to the crown.

0:27:34.960 --> 0:27:38.199
<v Speaker 1>I don't really have here much of the receding hairline

0:27:38.280 --> 0:27:41.399
<v Speaker 1>up front. But that's what's next, is the bald spot

0:27:41.400 --> 0:27:44.480
<v Speaker 1>on the crown or the vertex of the head. And

0:27:44.840 --> 0:27:49.399
<v Speaker 1>the idea is, in the cruelest possible form, is the

0:27:49.480 --> 0:27:53.560
<v Speaker 1>crown is losing it, the forehead is losing it, and

0:27:53.600 --> 0:27:57.680
<v Speaker 1>they say, hey, why don't we meet in the middle

0:27:57.720 --> 0:28:01.399
<v Speaker 1>and talk about this and that to what happened? They creep,

0:28:01.480 --> 0:28:05.320
<v Speaker 1>The crown creeps forward and the hairline creeps backward, and

0:28:05.359 --> 0:28:07.640
<v Speaker 1>eventually they meet in the middle and they go hey,

0:28:07.680 --> 0:28:11.360
<v Speaker 1>it's nice to meet you. I'm let's go on vacation forever.

0:28:11.960 --> 0:28:14.679
<v Speaker 1>And then you have no hair on the top of

0:28:14.680 --> 0:28:18.840
<v Speaker 1>your head. And if you if you let all your

0:28:18.880 --> 0:28:21.080
<v Speaker 1>hair grow, that's still there. You're gonna have that hair

0:28:21.160 --> 0:28:24.480
<v Speaker 1>on the sides and in the back because it's weird,

0:28:24.680 --> 0:28:27.479
<v Speaker 1>but it just it doesn't affect the sides in the

0:28:27.480 --> 0:28:30.800
<v Speaker 1>back of the hair in the same way the follicles

0:28:30.800 --> 0:28:34.399
<v Speaker 1>are are different. You basically you go from Gene Hackman

0:28:35.119 --> 0:28:39.720
<v Speaker 1>in the French connection to Gene Hackman in Absolute Power,

0:28:40.640 --> 0:28:42.920
<v Speaker 1>and eventually, if it keeps going, you end up as

0:28:42.960 --> 0:28:47.320
<v Speaker 1>Gene Hackman in Superman, okay, and then eventually the Royal

0:28:47.360 --> 0:28:52.960
<v Speaker 1>tannembombs and then you retire. Right but so um, there's

0:28:53.000 --> 0:28:58.360
<v Speaker 1>also this this possible outcome of the m receding hairline

0:28:58.440 --> 0:29:02.360
<v Speaker 1>meeting up with the bald spot on the crown in

0:29:02.480 --> 0:29:05.720
<v Speaker 1>that there's a little island tuft of hair in the

0:29:05.760 --> 0:29:10.120
<v Speaker 1>forehead that was like the dip or the the lowest

0:29:10.160 --> 0:29:12.200
<v Speaker 1>point of the M or the downward point of the

0:29:12.400 --> 0:29:15.640
<v Speaker 1>M that got left behind. So you still have a little,

0:29:15.800 --> 0:29:18.560
<v Speaker 1>a little cute, little tin tin patch of hair right there.

0:29:19.200 --> 0:29:21.520
<v Speaker 1>That is a possible outcome of this, but more likely

0:29:21.520 --> 0:29:23.400
<v Speaker 1>than not, you're gonna end up with just that ring

0:29:23.480 --> 0:29:26.600
<v Speaker 1>of hair, kind of like Patrick Steward and Star Trek

0:29:26.640 --> 0:29:30.080
<v Speaker 1>the next generation. Yeah, and and again it's because that

0:29:30.160 --> 0:29:32.240
<v Speaker 1>the hair on the sides, the follicles on the sides

0:29:32.280 --> 0:29:35.920
<v Speaker 1>and the back are naturally d HT resistant. Even if

0:29:35.920 --> 0:29:39.000
<v Speaker 1>you have that pattern baldness, it's you know, it's just

0:29:39.040 --> 0:29:42.160
<v Speaker 1>a shame it wasn't reverse because maybe it would be different.

0:29:42.200 --> 0:29:46.840
<v Speaker 1>But you know, people, it is a hairstyle to shave

0:29:46.960 --> 0:29:48.720
<v Speaker 1>the sides in the back and to have the faux

0:29:48.760 --> 0:29:53.560
<v Speaker 1>hawk or the mohawk or the sort of military looking cut. Um.

0:29:53.600 --> 0:29:57.320
<v Speaker 1>There is no hairstyle that is mere male pattern baldness.

0:29:57.320 --> 0:29:58.880
<v Speaker 1>I mean, you can, you can grow it out and

0:29:58.960 --> 0:30:00.640
<v Speaker 1>rocket kind of like Phil Colin did for a while

0:30:00.680 --> 0:30:02.880
<v Speaker 1>in the eighties and that and that's fine, man, we're

0:30:02.880 --> 0:30:06.320
<v Speaker 1>not yucking anyone's young. But if it were somehow reversed,

0:30:07.280 --> 0:30:08.920
<v Speaker 1>I don't think it would be as big of a deal,

0:30:10.080 --> 0:30:11.480
<v Speaker 1>like if you lost your hair on the sides and

0:30:11.480 --> 0:30:18.240
<v Speaker 1>in the back, you know, or would it be culturally

0:30:18.280 --> 0:30:21.880
<v Speaker 1>shifted to where that was like, oh boy, yeah, that's

0:30:21.880 --> 0:30:24.200
<v Speaker 1>that's exactly what happened. Because everybody's always got to have

0:30:24.200 --> 0:30:28.280
<v Speaker 1>a problem with something on everybody. Yeah, yeah, I think

0:30:28.320 --> 0:30:30.360
<v Speaker 1>it'd be bad either way. But I think I think

0:30:30.520 --> 0:30:34.240
<v Speaker 1>you're right. Phil Collins managed to rock it out. I think, um,

0:30:34.320 --> 0:30:38.600
<v Speaker 1>Bruce Willis did a great job with it as well. Um,

0:30:38.600 --> 0:30:40.720
<v Speaker 1>and he went he started shaving pretty early on too.

0:30:40.760 --> 0:30:43.240
<v Speaker 1>He he just went with it eventually, but he still

0:30:43.280 --> 0:30:45.800
<v Speaker 1>had the stubble. He didn't go like straight up like

0:30:46.280 --> 0:30:50.360
<v Speaker 1>you know, just like Jeff Bezos or anything like that. Yeah,

0:30:50.360 --> 0:30:56.520
<v Speaker 1>he eventually did like Travolta now, like props for finally

0:30:56.560 --> 0:30:59.720
<v Speaker 1>giving in and and getting rid. I mean I think

0:30:59.760 --> 0:31:02.080
<v Speaker 1>he he probably had hair plugs, which we'll get to

0:31:02.920 --> 0:31:05.040
<v Speaker 1>or at the very least whatever. You know, we'll talk

0:31:05.080 --> 0:31:09.080
<v Speaker 1>about the newer treatments. And uh, it's one of those

0:31:09.120 --> 0:31:12.479
<v Speaker 1>things where they're certain male actors where when you compare

0:31:12.520 --> 0:31:17.920
<v Speaker 1>photos of them today two photos of them, uh fifteen

0:31:18.000 --> 0:31:20.920
<v Speaker 1>years ago, and they have more hair now. It's one

0:31:20.920 --> 0:31:24.479
<v Speaker 1>of those things really all right. Uh, it's the Jeremy

0:31:24.480 --> 0:31:27.240
<v Speaker 1>Piman effect, Like I think we know what's happening here,

0:31:27.520 --> 0:31:32.960
<v Speaker 1>and you know, especially if you're an actor, uh, that

0:31:32.960 --> 0:31:36.080
<v Speaker 1>that is your I mean, it may be harder to

0:31:36.320 --> 0:31:38.520
<v Speaker 1>just embrace the like, all right, I'll just shave my

0:31:38.560 --> 0:31:42.000
<v Speaker 1>head thing because you may think you may not work

0:31:42.040 --> 0:31:44.800
<v Speaker 1>as much or something, or you may not be appropriate

0:31:44.800 --> 0:31:46.560
<v Speaker 1>for certain kinds of roles you want to get. So

0:31:47.440 --> 0:31:49.680
<v Speaker 1>you know, I could see them tying it into work somehow.

0:31:49.800 --> 0:31:53.240
<v Speaker 1>And and certainly actors are not historically short on ego,

0:31:53.560 --> 0:31:55.440
<v Speaker 1>so that plays a part as well. Sure. I was

0:31:55.480 --> 0:31:58.320
<v Speaker 1>reading a BBC article and then interviewed an actor named

0:31:58.360 --> 0:32:02.560
<v Speaker 1>James Nesbit who's fairly well known, and he um credited

0:32:03.280 --> 0:32:08.040
<v Speaker 1>his hair restoration with basically restoration of his career. He

0:32:08.080 --> 0:32:11.320
<v Speaker 1>started getting parts again that he was getting passed over for.

0:32:11.520 --> 0:32:14.320
<v Speaker 1>He said, his confidence went up, and I mean, more

0:32:14.360 --> 0:32:16.520
<v Speaker 1>power to you. If you want to do something about

0:32:16.560 --> 0:32:18.120
<v Speaker 1>your hair loss, that's fine. If you want to go

0:32:18.160 --> 0:32:20.720
<v Speaker 1>to the Travolta way, that's fine too. But yeah, I

0:32:20.760 --> 0:32:24.760
<v Speaker 1>mean that's um. I think people who who are like, yeah,

0:32:24.760 --> 0:32:27.719
<v Speaker 1>there's before and after pictures, like there's a very famous

0:32:27.720 --> 0:32:31.080
<v Speaker 1>one of elaw and musk Um in his PayPal days.

0:32:31.120 --> 0:32:34.080
<v Speaker 1>He was young, very young when he started to thin

0:32:34.840 --> 0:32:37.400
<v Speaker 1>pretty dramatically. And then now if you like at Elon

0:32:37.480 --> 0:32:40.480
<v Speaker 1>Muski has a beautiful, full head of hair, and I

0:32:40.520 --> 0:32:45.560
<v Speaker 1>think Um, he cares exactly bagel of whether you realize

0:32:45.560 --> 0:32:47.320
<v Speaker 1>that he got hair plugs or not, because he's got

0:32:47.360 --> 0:32:51.760
<v Speaker 1>hair again, so he probably invented some treatment that only

0:32:51.800 --> 0:32:54.880
<v Speaker 1>he is pretty too. That's right, that's right. But then

0:32:54.880 --> 0:32:58.440
<v Speaker 1>if you look at Jeff Bezos, the he went the

0:32:58.480 --> 0:33:00.960
<v Speaker 1>other way. He's definitely got a few bucks that he

0:33:00.960 --> 0:33:03.560
<v Speaker 1>could spend on that, I would guess, and he decided

0:33:03.600 --> 0:33:07.880
<v Speaker 1>not to, which I'm surprised by. Actually, he seems like

0:33:07.920 --> 0:33:13.520
<v Speaker 1>the type who would go full like, yeah, maybe Bob Ross,

0:33:13.560 --> 0:33:16.840
<v Speaker 1>maybe yeah. I mean, he could have a an underground

0:33:16.880 --> 0:33:22.400
<v Speaker 1>illegal scalp farm for all we know that he's mining, right,

0:33:22.520 --> 0:33:26.760
<v Speaker 1>has nothing to do with with with hair growth. He's

0:33:26.800 --> 0:33:29.200
<v Speaker 1>looking at sell that stuff. They'll deliver it to your

0:33:29.240 --> 0:33:32.960
<v Speaker 1>porch via drone one day, right, something like robot just

0:33:33.040 --> 0:33:35.680
<v Speaker 1>drops a bloody scalp on your porch and a big thud.

0:33:36.920 --> 0:33:39.440
<v Speaker 1>There you go put it on. I didn't order to

0:33:39.480 --> 0:33:44.680
<v Speaker 1>just put it on the drone watching you tremble. So

0:33:45.080 --> 0:33:48.160
<v Speaker 1>that is male pattern baldness. With women, if they suffer

0:33:48.160 --> 0:33:51.040
<v Speaker 1>from pattern baldness, it is going to be uh, not

0:33:51.160 --> 0:33:55.000
<v Speaker 1>as predictable. It's not like male pattern baldness in that

0:33:55.760 --> 0:33:58.560
<v Speaker 1>the thinning kind of happens more everywhere. It's not like

0:33:58.600 --> 0:34:00.520
<v Speaker 1>it just happens from front to back and then you

0:34:00.560 --> 0:34:02.880
<v Speaker 1>lose all your hair in that you shape that kind

0:34:02.880 --> 0:34:06.360
<v Speaker 1>of horseshoe pattern. It is much slower than male pattern balding.

0:34:07.160 --> 0:34:11.040
<v Speaker 1>And again it's because they have low testosterone and low

0:34:11.120 --> 0:34:15.279
<v Speaker 1>d h D as a result. But again it's women. Um,

0:34:15.440 --> 0:34:19.040
<v Speaker 1>I'm sorry, fort of pattern baldness are women who suffer

0:34:19.120 --> 0:34:21.799
<v Speaker 1>from it? So uh and it is a thing, you know.

0:34:22.000 --> 0:34:25.600
<v Speaker 1>You know, a woman's hair is very important to their

0:34:25.800 --> 0:34:29.960
<v Speaker 1>esteem and and their body image. So when a woman's

0:34:30.000 --> 0:34:32.800
<v Speaker 1>hair starts thinning and falling out, it is just as traumatic.

0:34:33.280 --> 0:34:35.840
<v Speaker 1>I would say more, I would argue much more. And

0:34:36.080 --> 0:34:38.719
<v Speaker 1>yeah maybe so, I mean it is certainly not and

0:34:38.760 --> 0:34:41.960
<v Speaker 1>maybe more so because there's not as much attention paid

0:34:42.000 --> 0:34:44.480
<v Speaker 1>and maybe like, hey, is anyone even listening that this

0:34:44.560 --> 0:34:47.399
<v Speaker 1>is an issue? Well, I think women are unfairly held

0:34:47.440 --> 0:34:52.040
<v Speaker 1>to even more um beauty standards than men. You know.

0:34:52.120 --> 0:34:54.160
<v Speaker 1>Oh yeah, like guys, really good to shave your head?

0:34:54.160 --> 0:34:56.600
<v Speaker 1>Who cares? It's fine, that's that's a cool look. Yeah,

0:34:57.640 --> 0:35:01.480
<v Speaker 1>women also have their own scaled Ludwig scale, or if

0:35:01.520 --> 0:35:05.160
<v Speaker 1>you want to get fancy the Ludwig scale. They have

0:35:05.239 --> 0:35:08.480
<v Speaker 1>type one to three, and apparently the thinning um is

0:35:08.520 --> 0:35:12.880
<v Speaker 1>tracked on the Ludwig scale along the natural part, and

0:35:13.320 --> 0:35:15.760
<v Speaker 1>you know, type one to three is just different degrees

0:35:15.840 --> 0:35:18.120
<v Speaker 1>of how thin it is along the natural part of

0:35:18.120 --> 0:35:22.080
<v Speaker 1>the woman's hair. That's right. Should we take another break. Yeah,

0:35:22.160 --> 0:35:23.400
<v Speaker 1>let's take a break and then we'll come back and

0:35:23.440 --> 0:35:25.440
<v Speaker 1>talk about all of the things people have been doing

0:35:25.480 --> 0:35:56.480
<v Speaker 1>for thousands of years to combat hair loss. Shot. All right,

0:35:56.800 --> 0:35:59.680
<v Speaker 1>So this is one thing I know for a fact.

0:36:00.239 --> 0:36:02.680
<v Speaker 1>If you are a young man and you are wondering

0:36:02.719 --> 0:36:05.239
<v Speaker 1>if this is in your future, just look at your

0:36:05.280 --> 0:36:09.320
<v Speaker 1>mom's dad, and you've solved the problem. So that is

0:36:09.360 --> 0:36:14.960
<v Speaker 1>a myth. Allegedly, Yes, oh you will hurt man. You're

0:36:15.160 --> 0:36:18.239
<v Speaker 1>just an amazing actor. You always say you're not, and

0:36:18.320 --> 0:36:22.320
<v Speaker 1>you really are. Allegedly, I mean, I don't think they've

0:36:22.480 --> 0:36:24.759
<v Speaker 1>they've said outright, it has nothing to do with it.

0:36:24.880 --> 0:36:27.440
<v Speaker 1>Right now, there was a German study from two thousand

0:36:27.480 --> 0:36:30.279
<v Speaker 1>five that actually found there's a little bit on the

0:36:30.440 --> 0:36:35.080
<v Speaker 1>X chromosome that baldmin share in common. So it's possible

0:36:35.120 --> 0:36:38.360
<v Speaker 1>because you get your X chromosome from your mom and

0:36:38.400 --> 0:36:41.000
<v Speaker 1>there's a fifty chance that the X chromosome came from

0:36:41.000 --> 0:36:44.120
<v Speaker 1>your grandfather, that's where the basis of that old myths

0:36:44.239 --> 0:36:46.959
<v Speaker 1>came from. It may be true, but what they seem

0:36:47.040 --> 0:36:50.880
<v Speaker 1>to be thinking is that there's way more genes involved

0:36:50.920 --> 0:36:54.840
<v Speaker 1>in saying just one on the X chromosome, Um that

0:36:54.840 --> 0:36:59.080
<v Speaker 1>that are involved in pattern baldness. But the upshot of

0:36:59.080 --> 0:37:02.120
<v Speaker 1>it is, um, if you really want to know whether

0:37:02.160 --> 0:37:04.720
<v Speaker 1>you're going to go bald, are your chances of going bald?

0:37:05.280 --> 0:37:08.680
<v Speaker 1>How many bald men are there in your in your family?

0:37:08.760 --> 0:37:11.879
<v Speaker 1>That's really what yeah, like on both sides, just start

0:37:11.920 --> 0:37:16.080
<v Speaker 1>looking at old family albums and uh, maybe pour yourself

0:37:16.080 --> 0:37:19.680
<v Speaker 1>a drink sure to steady your nerves. Yeah, I mean

0:37:19.719 --> 0:37:21.880
<v Speaker 1>we have pretty good hair and my family my you know,

0:37:21.960 --> 0:37:26.759
<v Speaker 1>my brother he has this legendary thick black wavy hair.

0:37:26.800 --> 0:37:32.799
<v Speaker 1>It's just infuriating get a trophy. But like my grandfather,

0:37:32.880 --> 0:37:36.439
<v Speaker 1>my mom's dad, he died with a big thick head

0:37:36.480 --> 0:37:40.840
<v Speaker 1>of cur curly hair. And my uncle's my mom's brothers

0:37:40.880 --> 0:37:45.600
<v Speaker 1>both have really robust hair. Still my brother does. My

0:37:45.680 --> 0:37:48.759
<v Speaker 1>dad's I'm pretty much my dad. I mean, my dad

0:37:48.800 --> 0:37:53.080
<v Speaker 1>now is eighty ish and um, he started thinning on

0:37:53.080 --> 0:37:55.200
<v Speaker 1>the crown. You know quite a few years ago, and

0:37:55.360 --> 0:37:57.319
<v Speaker 1>it's it's pretty thin on top, but it never like

0:37:58.360 --> 0:38:01.040
<v Speaker 1>it never went away on top. It's just pretty thin.

0:38:01.280 --> 0:38:03.560
<v Speaker 1>My dad did the same thing. It's like he's got

0:38:03.560 --> 0:38:08.040
<v Speaker 1>a pretty decent circle. You can calibrate a compass by,

0:38:08.080 --> 0:38:12.839
<v Speaker 1>but it's it is like, um, it's stayed. He's he's

0:38:12.880 --> 0:38:17.280
<v Speaker 1>gonna be eighty three this year, and it's just it's stayed.

0:38:17.320 --> 0:38:19.960
<v Speaker 1>He's still got you know, hair in between his forehead

0:38:20.000 --> 0:38:23.520
<v Speaker 1>and the crown of his head on the sides. Um,

0:38:23.600 --> 0:38:26.560
<v Speaker 1>So I anticipate mineill Polly be similar because I'm tracking

0:38:27.080 --> 0:38:32.680
<v Speaker 1>a very similar pattern that he he tracked as well. Yeah.

0:38:32.760 --> 0:38:36.279
<v Speaker 1>I even have the same haircut these days as is

0:38:36.320 --> 0:38:39.719
<v Speaker 1>your dad. Yeah, from the seventies. Is it pretty long

0:38:39.800 --> 0:38:43.560
<v Speaker 1>right now? Yeah, it's pretty It's pretty long. And think, yeah,

0:38:43.640 --> 0:38:46.040
<v Speaker 1>which is good. It's good. I'm happy with it. But

0:38:46.080 --> 0:38:48.160
<v Speaker 1>I definitely have that balts by just like just like

0:38:48.239 --> 0:38:51.239
<v Speaker 1>dear old dad has well, I had been. I had

0:38:51.320 --> 0:38:54.239
<v Speaker 1>shaved my head I think more than ever before in

0:38:54.600 --> 0:38:56.520
<v Speaker 1>lockdown over the past year. I shaved it fully I

0:38:56.520 --> 0:39:00.560
<v Speaker 1>think three times, and then did a couple of drunk

0:39:00.640 --> 0:39:05.680
<v Speaker 1>in late night um, completely bald on the sides sort

0:39:05.680 --> 0:39:09.839
<v Speaker 1>of Hawkeye and the last of Injuris movie look okay, uh,

0:39:09.840 --> 0:39:11.560
<v Speaker 1>and it was kind of cool. I kind of liked

0:39:11.600 --> 0:39:15.480
<v Speaker 1>it cool. I have not been doing anything experimental with

0:39:15.520 --> 0:39:17.799
<v Speaker 1>my hair. Actually, m has been doing a good job

0:39:17.840 --> 0:39:21.200
<v Speaker 1>of keeping me from looking like totally shaggy. She's she's

0:39:21.239 --> 0:39:24.120
<v Speaker 1>just clean and coming hair. Yeah, that's good. Um yeah.

0:39:24.200 --> 0:39:26.560
<v Speaker 1>And and definitely like shaving the neck that gets kind

0:39:26.560 --> 0:39:28.960
<v Speaker 1>of burly back there, but I haven't. I haven't shaved

0:39:28.960 --> 0:39:31.080
<v Speaker 1>my head in years and years and years. It's just

0:39:31.120 --> 0:39:33.520
<v Speaker 1>not a very good look for me. Oh no, no,

0:39:33.600 --> 0:39:36.880
<v Speaker 1>I like that. I never did. I never liked pictures

0:39:36.880 --> 0:39:41.560
<v Speaker 1>of me. Yeah, especially the shaved head with glasses. I'm like, boy,

0:39:41.560 --> 0:39:43.120
<v Speaker 1>I saw an old picture of us the other day

0:39:43.120 --> 0:39:45.360
<v Speaker 1>that was I'll just say it was pretty funny and

0:39:45.400 --> 0:39:47.359
<v Speaker 1>I was gonna Instagram and I was like, Josh should

0:39:47.360 --> 0:39:50.680
<v Speaker 1>be really mad if my Instagram. Oh yeah what I Oh,

0:39:50.800 --> 0:39:53.120
<v Speaker 1>it just wasn't your best look. You're you. You've come

0:39:53.120 --> 0:39:55.600
<v Speaker 1>a long way, baby. Oh I'm not. I'm not shy

0:39:55.640 --> 0:39:59.279
<v Speaker 1>about that kind of thing. I know now. I'm an

0:39:59.280 --> 0:40:03.520
<v Speaker 1>admis though, so who cares? So again, look at the

0:40:03.520 --> 0:40:06.600
<v Speaker 1>pictures of all your family I think, uh, it does

0:40:06.640 --> 0:40:11.839
<v Speaker 1>increase with age. If you're white man, about of us

0:40:12.280 --> 0:40:16.000
<v Speaker 1>are going to experience, um, some sort of pattern involving

0:40:16.040 --> 0:40:20.160
<v Speaker 1>in your twenties. Um, and that's you know, that's that

0:40:20.239 --> 0:40:22.240
<v Speaker 1>can be rough if you're if you're in your twenties

0:40:22.280 --> 0:40:25.040
<v Speaker 1>and you start to lose your hair um in your

0:40:25.080 --> 0:40:28.240
<v Speaker 1>thirties and then so on and so on. I think women,

0:40:28.360 --> 0:40:31.200
<v Speaker 1>I think usually see it later, usually in their forties

0:40:31.239 --> 0:40:36.399
<v Speaker 1>and fifties, and menopause can actually kick it off for women. Right,

0:40:37.239 --> 0:40:39.879
<v Speaker 1>Because again, hair growth and sex hormones are very much

0:40:39.920 --> 0:40:44.719
<v Speaker 1>tied together. So any fluctuation, weirdness, any sudden change, all

0:40:44.760 --> 0:40:48.120
<v Speaker 1>of that stuff, uh, can can have some sort of

0:40:48.160 --> 0:40:51.880
<v Speaker 1>effect on your hair growth or hair loss. So that

0:40:51.960 --> 0:40:55.799
<v Speaker 1>must mean if you have like tons of testosterone and

0:40:55.840 --> 0:41:00.160
<v Speaker 1>you're that dude, you must be really really bald for

0:41:00.200 --> 0:41:08.120
<v Speaker 1>early right. You keep getting me. That's another myth, right, Yeah,

0:41:08.200 --> 0:41:12.680
<v Speaker 1>there's like supposedly people who are bald have no more

0:41:12.840 --> 0:41:16.680
<v Speaker 1>testosterone levels in their body in general than people who

0:41:16.719 --> 0:41:19.919
<v Speaker 1>have a full head of hair. So we're busting myths

0:41:19.960 --> 0:41:22.200
<v Speaker 1>all over the place. Chuck, Well, why don't we talk

0:41:22.239 --> 0:41:25.520
<v Speaker 1>about some of these? It's always fun. Sawbone style to

0:41:25.520 --> 0:41:31.120
<v Speaker 1>talk about some antiquated medical practices in the fifteen fifties

0:41:31.120 --> 0:41:35.640
<v Speaker 1>b C. Egyptians would everyone's always been rubbing stuff on

0:41:35.680 --> 0:41:37.440
<v Speaker 1>their head to see if they could regrow it. It

0:41:37.520 --> 0:41:41.600
<v Speaker 1>was hippopotamus fat, porcupine hair they would boil in water.

0:41:41.880 --> 0:41:44.520
<v Speaker 1>They would grind up donkey hoofs and rub that into

0:41:44.560 --> 0:41:47.840
<v Speaker 1>their scalp. Yeah. Uh. And then that was on the

0:41:47.840 --> 0:41:49.840
<v Speaker 1>Ebbers papyrus, which I think we talked about in the

0:41:49.920 --> 0:41:54.440
<v Speaker 1>Ethnobotany episode. Yeah. Um. And then about a thousand, eleven

0:41:54.520 --> 0:41:58.520
<v Speaker 1>hundred or so years later, our buddy Hippocrisies shows back up,

0:41:59.160 --> 0:42:02.239
<v Speaker 1>makes the comparison with Foxes with Mange, which is not

0:42:02.360 --> 0:42:05.399
<v Speaker 1>very pleasant, and then also says, hey, get your hands

0:42:05.400 --> 0:42:09.040
<v Speaker 1>on some opium and horseradish, get some pigeon poop and

0:42:09.120 --> 0:42:13.960
<v Speaker 1>some beats and uh spices, like he's suddenly Colonel Sanders

0:42:14.080 --> 0:42:17.759
<v Speaker 1>or something. Put it all together, right, yeah, and then

0:42:17.760 --> 0:42:20.040
<v Speaker 1>there you go. You're fine after that. You don't care

0:42:20.040 --> 0:42:22.879
<v Speaker 1>about your hair loss any that's right, um. And then

0:42:23.040 --> 0:42:25.839
<v Speaker 1>put it all together and rub it on your head. Uh.

0:42:25.880 --> 0:42:29.600
<v Speaker 1>And apparently he also said, you know what, court eunuchs

0:42:29.800 --> 0:42:32.640
<v Speaker 1>um tend to have really nice hair. Which I've never seen.

0:42:32.680 --> 0:42:36.759
<v Speaker 1>I've always seen him bald, but he said, if you

0:42:36.800 --> 0:42:39.560
<v Speaker 1>have really bad hair lost, just go ahead and castrate yourself.

0:42:39.600 --> 0:42:42.840
<v Speaker 1>And there you go. I'm Hippocrates, go ahead and base

0:42:42.880 --> 0:42:47.400
<v Speaker 1>all medical science after my teachings. About a thousand a d.

0:42:47.560 --> 0:42:50.279
<v Speaker 1>There was a Celtic remedy for you had to hunt

0:42:50.280 --> 0:42:52.919
<v Speaker 1>down a raven, burn it and then mix up those

0:42:52.920 --> 0:42:55.640
<v Speaker 1>ashes and render it was some sheep fat. Rub that

0:42:55.719 --> 0:43:00.000
<v Speaker 1>on your head, right, And then of course the Kellogg brothers.

0:43:00.040 --> 0:43:02.200
<v Speaker 1>I don't think it wouldn't surprise me if they had

0:43:02.200 --> 0:43:05.719
<v Speaker 1>a machine, but they were very Kellogg like machines by

0:43:05.719 --> 0:43:08.719
<v Speaker 1>the twentieth century, where I think there was one called

0:43:08.760 --> 0:43:11.880
<v Speaker 1>the Crossley Servac that if you look a picture of this,

0:43:11.960 --> 0:43:14.399
<v Speaker 1>it is very Kellogg like. It's a you know, this

0:43:14.440 --> 0:43:16.520
<v Speaker 1>big machine and you would sit with a like a

0:43:16.600 --> 0:43:20.160
<v Speaker 1>bowl on your head that was connected to and I

0:43:20.200 --> 0:43:23.040
<v Speaker 1>think it would supposedly try and literally suck hair from

0:43:23.080 --> 0:43:26.480
<v Speaker 1>your scalp. Yeah, apparently Fredis Stair had one, and I

0:43:26.520 --> 0:43:30.319
<v Speaker 1>mean the Cross League Company still to this day has

0:43:30.400 --> 0:43:33.839
<v Speaker 1>on their blog a little article about it and they

0:43:34.400 --> 0:43:37.000
<v Speaker 1>say that you know, it worked, it seemed to really work.

0:43:37.200 --> 0:43:41.480
<v Speaker 1>Something about it worked but they're not exactly sure why. Um.

0:43:41.520 --> 0:43:46.440
<v Speaker 1>There's another thing called the thermocap that used like um

0:43:47.000 --> 0:43:50.080
<v Speaker 1>heat and blue light, and I know there's one today

0:43:50.080 --> 0:43:54.040
<v Speaker 1>called the Capellus which uses some sort of maybe red

0:43:54.120 --> 0:43:57.439
<v Speaker 1>or infrared light UM. And there's a class action suit

0:43:57.440 --> 0:44:00.640
<v Speaker 1>against Capellus right now because they have a claim that

0:44:01.160 --> 0:44:05.560
<v Speaker 1>it's clinically proven to regrow hair. And apparently that clinically

0:44:05.600 --> 0:44:08.360
<v Speaker 1>proven is based on a single two thousand and fourteen

0:44:08.400 --> 0:44:11.919
<v Speaker 1>clinical trial that was sponsored by Capellus. So somebody who

0:44:12.000 --> 0:44:14.640
<v Speaker 1>tried spent seven hundred bucks on a Capellus system is

0:44:14.640 --> 0:44:17.160
<v Speaker 1>suing them, and that a bunch of other people have joined.

0:44:18.280 --> 0:44:21.400
<v Speaker 1>As far as real things that work, we mentioned the

0:44:21.480 --> 0:44:24.840
<v Speaker 1>onset of the show, there are a couple of drugs

0:44:24.880 --> 0:44:28.880
<v Speaker 1>that have we're sort of accidental and uh in this

0:44:29.160 --> 0:44:31.480
<v Speaker 1>so far as the side effect they found was that

0:44:31.520 --> 0:44:35.320
<v Speaker 1>it helped regrow hair and medoxidil active ingredient, and rogain

0:44:35.440 --> 0:44:38.400
<v Speaker 1>is one of them. In the eighties, it was developed

0:44:38.400 --> 0:44:42.440
<v Speaker 1>as a blood pressure medication and it's a vasidilator, so

0:44:42.440 --> 0:44:45.920
<v Speaker 1>it's gonna enlarge blood vessels and they think, um that

0:44:46.000 --> 0:44:47.960
<v Speaker 1>what it does is in large hair follicles that are

0:44:48.000 --> 0:44:51.000
<v Speaker 1>shrinking due to that pattern baldness and just slows that

0:44:51.040 --> 0:44:54.840
<v Speaker 1>process down and it works pretty good. I think UM,

0:44:54.880 --> 0:44:59.240
<v Speaker 1>supposedly it it. I don't think it's uh. It depends

0:44:59.239 --> 0:45:02.760
<v Speaker 1>on what you're after. Like I think they say um

0:45:02.960 --> 0:45:06.080
<v Speaker 1>hair regrowth because that's what you want. You want to

0:45:06.280 --> 0:45:08.160
<v Speaker 1>you want to start early and stop it in its

0:45:08.160 --> 0:45:11.560
<v Speaker 1>tracks and try to regrows some. So for hair regrowth

0:45:12.000 --> 0:45:15.640
<v Speaker 1>was found to be very effective and only sixteen um

0:45:15.719 --> 0:45:19.000
<v Speaker 1>effective or moderately effective in six which is pretty good

0:45:19.160 --> 0:45:21.319
<v Speaker 1>of men, you should say, yeah, of men, and then

0:45:21.320 --> 0:45:27.000
<v Speaker 1>ineffective in sixteen percent. I think for women reported moderate

0:45:27.360 --> 0:45:30.600
<v Speaker 1>hair regrowth with medocodel, and that's just for a hair

0:45:30.640 --> 0:45:32.600
<v Speaker 1>on the top of your head. It has apparently zero

0:45:32.680 --> 0:45:35.239
<v Speaker 1>effect on the hair on the side of your head. Yeah,

0:45:35.280 --> 0:45:37.520
<v Speaker 1>like that crown. If that's where you're losing it and

0:45:37.520 --> 0:45:39.880
<v Speaker 1>you get in there early with that road game, that's uh,

0:45:39.960 --> 0:45:41.560
<v Speaker 1>you might want to give that a shot. Yeah, And

0:45:41.560 --> 0:45:44.800
<v Speaker 1>they think basically it's just UM opening up the blood

0:45:44.840 --> 0:45:48.640
<v Speaker 1>supply to those you know, withering hair follicles and gets them,

0:45:48.680 --> 0:45:52.600
<v Speaker 1>gets those gremlins working again. That's right, makes sense. There's

0:45:52.600 --> 0:45:58.120
<v Speaker 1>also finasteride um, which was originally under the trade name Propecia.

0:45:58.440 --> 0:46:01.279
<v Speaker 1>I think the patent ran out on it, and I

0:46:01.320 --> 0:46:04.359
<v Speaker 1>think by now, uh, if not, monoxide will definitely did

0:46:04.400 --> 0:46:06.800
<v Speaker 1>because that was ro gain. One of the two is

0:46:07.440 --> 0:46:11.000
<v Speaker 1>not in the patent phase any longer. But it was

0:46:11.040 --> 0:46:15.799
<v Speaker 1>originally developed to shrink in large prostates because it's a

0:46:16.040 --> 0:46:21.160
<v Speaker 1>UM five alpha reductase inhibitor. UM and in large prostates

0:46:21.200 --> 0:46:26.160
<v Speaker 1>are the result of die hydro testosterone. So um rogain

0:46:26.280 --> 0:46:32.040
<v Speaker 1>or finasteride basically inhibits five alpha reductations from converting testosterone

0:46:32.239 --> 0:46:36.600
<v Speaker 1>into die hydro testosterone or d HT. So that would

0:46:36.600 --> 0:46:41.120
<v Speaker 1>reduce hair loss because there's less DHT in the hair follicles, right,

0:46:41.239 --> 0:46:44.640
<v Speaker 1>and finasteride is is I think rogains a foam like

0:46:44.840 --> 0:46:48.799
<v Speaker 1>hair moose or maybe like a gelled a liquid too,

0:46:49.040 --> 0:46:52.759
<v Speaker 1>and then finasteride like we don't know, and then I'm

0:46:52.840 --> 0:46:55.080
<v Speaker 1>just kidding. Actually did buy some rogaine. I use it

0:46:55.120 --> 0:46:56.840
<v Speaker 1>for like two weeks and I was like, I'm not

0:46:56.880 --> 0:46:58.879
<v Speaker 1>gonna do this for the rest of the Yeah, well

0:46:58.880 --> 0:47:02.200
<v Speaker 1>that's stopped. You got We should say, like, um, both

0:47:02.280 --> 0:47:06.400
<v Speaker 1>monoxidet and in finasteride have to be used beforeever for

0:47:06.440 --> 0:47:08.080
<v Speaker 1>as long as you want to keep trying to work

0:47:08.120 --> 0:47:10.440
<v Speaker 1>on your hair. Yeah, I ran up and it was

0:47:10.520 --> 0:47:11.960
<v Speaker 1>just one of those things. I have a hard time

0:47:12.040 --> 0:47:14.799
<v Speaker 1>doing a thing every day anyway, and I was like,

0:47:15.040 --> 0:47:17.400
<v Speaker 1>they just did not last. So I've got three or

0:47:17.400 --> 0:47:20.239
<v Speaker 1>four things of If anyone wants some free rogaine, I'll

0:47:20.239 --> 0:47:22.400
<v Speaker 1>send it to him. Oh, that's nice of you. I'll

0:47:22.440 --> 0:47:24.680
<v Speaker 1>just mail you in my leftover things. I'm sure that

0:47:25.040 --> 0:47:27.279
<v Speaker 1>that's nice. It's if it's over the counter. I think

0:47:27.320 --> 0:47:30.799
<v Speaker 1>we're okay legally speaking. And one more thing about finasteride,

0:47:30.840 --> 0:47:33.440
<v Speaker 1>Chuck is is it's like you're saying, it produces a

0:47:33.480 --> 0:47:36.640
<v Speaker 1>rectile dysfunction and loss of interest in sex and men,

0:47:37.280 --> 0:47:41.680
<v Speaker 1>and then in animal studies it produced um birth effects

0:47:41.719 --> 0:47:45.839
<v Speaker 1>in male genitalia for pregnant animals. So it's been that's

0:47:45.840 --> 0:47:50.320
<v Speaker 1>been kind of um extended to pregnant women human women,

0:47:50.440 --> 0:47:53.640
<v Speaker 1>saying like, if you don't get anywhere near finasteride because

0:47:53.680 --> 0:47:57.560
<v Speaker 1>it may produce birth effects in your baby. I did

0:47:57.560 --> 0:48:00.680
<v Speaker 1>not know that. Well. The one of the reasons you

0:48:00.719 --> 0:48:04.240
<v Speaker 1>did not know that is because apparently there's lawsuit against

0:48:04.320 --> 0:48:10.399
<v Speaker 1>Merk and this judge in Brooklyn, Judge Brian Cogan, allowed this.

0:48:10.719 --> 0:48:14.399
<v Speaker 1>These documents Merk internal documents to be sealed. That basically said, yeah,

0:48:14.440 --> 0:48:16.319
<v Speaker 1>we're well aware of this and we can't let this

0:48:16.360 --> 0:48:20.640
<v Speaker 1>get out because people won't want um propitia any longer

0:48:20.680 --> 0:48:25.560
<v Speaker 1>if they know about the prolonged sexual side effects, which

0:48:25.600 --> 0:48:29.080
<v Speaker 1>is terrible. That is terrible. So then you get the

0:48:29.080 --> 0:48:31.880
<v Speaker 1>hair plugs that we talked about. This was from the

0:48:31.960 --> 0:48:35.919
<v Speaker 1>nineteen fifties. Uh, sometimes it looks that way. Um. Dr

0:48:36.040 --> 0:48:39.680
<v Speaker 1>Norman or in Treaque or or in Treach, I'm not

0:48:39.719 --> 0:48:43.640
<v Speaker 1>sure which it is, came up with this um sort

0:48:43.680 --> 0:48:46.800
<v Speaker 1>of crude method where they would punch out little circles

0:48:46.800 --> 0:48:49.520
<v Speaker 1>of skin from a donor side on the back of

0:48:49.520 --> 0:48:52.000
<v Speaker 1>your head where you still you know, like we said,

0:48:52.040 --> 0:48:55.200
<v Speaker 1>the follicles are working great back there, and these were

0:48:55.239 --> 0:48:58.520
<v Speaker 1>little plugs about four millimeters in diameter, and then they

0:48:58.520 --> 0:49:02.520
<v Speaker 1>would transplant those to where you were balding and hopefully

0:49:02.560 --> 0:49:06.560
<v Speaker 1>regrow your hair. And it was it didn't look great

0:49:06.640 --> 0:49:09.919
<v Speaker 1>at less scars in the back, and it took time

0:49:09.960 --> 0:49:12.120
<v Speaker 1>for it to grow in upfront, so it would look

0:49:12.280 --> 0:49:16.480
<v Speaker 1>very sort of planted if you will. Well, yeah, I

0:49:16.520 --> 0:49:20.320
<v Speaker 1>mean it's like in these neat little rows, these little

0:49:20.320 --> 0:49:22.799
<v Speaker 1>plugs of hair, you know, like that. It left a

0:49:22.800 --> 0:49:25.359
<v Speaker 1>lot to be desired for sure. That's it has come

0:49:25.400 --> 0:49:28.000
<v Speaker 1>a long way since then. Now they use something called

0:49:28.520 --> 0:49:34.000
<v Speaker 1>f U E follicular unit extraction, and that allows them

0:49:34.000 --> 0:49:38.120
<v Speaker 1>to extract what they call follicular units three or four

0:49:38.160 --> 0:49:41.680
<v Speaker 1>follicles and there's no scarring back there, and they can

0:49:41.680 --> 0:49:44.799
<v Speaker 1>transplant them much more closely and fill in you know,

0:49:45.280 --> 0:49:47.160
<v Speaker 1>if it's if you were liking it to like a

0:49:47.280 --> 0:49:50.880
<v Speaker 1>row of corn, uh, filling in those rows in between

0:49:50.920 --> 0:49:54.440
<v Speaker 1>as well, so it looked better, yeah, where it was thinning.

0:49:54.800 --> 0:49:57.760
<v Speaker 1>You know. Something interesting I saw is that um doctor

0:49:58.320 --> 0:50:01.600
<v Speaker 1>or in treach, he followed in the footsteps of some

0:50:01.680 --> 0:50:05.480
<v Speaker 1>other people that data back to. There was a Turkey

0:50:05.520 --> 0:50:09.960
<v Speaker 1>believing manach Um Hodara, who apparently was the first one

0:50:10.000 --> 0:50:12.799
<v Speaker 1>to really do a hair transplant procedure. And then there

0:50:12.840 --> 0:50:16.680
<v Speaker 1>was a Japanese guy doctors show Jewey Okada, who in

0:50:16.680 --> 0:50:19.360
<v Speaker 1>the thirties was the one who pioneered that punch technique.

0:50:19.560 --> 0:50:22.640
<v Speaker 1>But in the West, Dr Orange Treats usually is credited

0:50:22.640 --> 0:50:26.440
<v Speaker 1>as the pioneer of hair transplants. Now they are starting

0:50:26.480 --> 0:50:29.359
<v Speaker 1>to look into stem cells and this has a lot

0:50:29.400 --> 0:50:33.239
<v Speaker 1>of promise because researchers found out I guess figured out

0:50:33.280 --> 0:50:35.960
<v Speaker 1>through a lot of study is that one of the

0:50:36.000 --> 0:50:40.240
<v Speaker 1>reasons that why hair follicles are can continue, those gremlins

0:50:40.280 --> 0:50:43.799
<v Speaker 1>can keep working is because each hair follicle has a

0:50:43.800 --> 0:50:49.240
<v Speaker 1>little well of stem cells, including those follicular stem cells

0:50:49.280 --> 0:50:52.799
<v Speaker 1>and dermal papilla cells that you were talking about. I

0:50:52.800 --> 0:50:56.359
<v Speaker 1>think at the very beginning and in Japan and here

0:50:56.360 --> 0:50:58.279
<v Speaker 1>in the States, there were scientists who figure out how

0:50:58.280 --> 0:51:02.279
<v Speaker 1>to extract those stem cells grow these new follicles in

0:51:02.280 --> 0:51:06.319
<v Speaker 1>a lab. And the thing with anytime you're doing that,

0:51:06.360 --> 0:51:08.880
<v Speaker 1>you have to you have to shape this thing. Like

0:51:08.920 --> 0:51:12.400
<v Speaker 1>if you're gonna, uh do something in the shape of

0:51:12.440 --> 0:51:14.880
<v Speaker 1>an ear, you would three D print out this like

0:51:14.960 --> 0:51:17.880
<v Speaker 1>a model, this like scaffolding model to allow it to

0:51:17.920 --> 0:51:21.600
<v Speaker 1>grow into the right shape. Because growing something from stem cells,

0:51:21.760 --> 0:51:25.120
<v Speaker 1>you know, organs from stem cells, it's you know, you've

0:51:25.120 --> 0:51:27.359
<v Speaker 1>gotta shape it yourself. It's not you can't just say

0:51:27.640 --> 0:51:29.920
<v Speaker 1>form of an ear or form of a hair follicle.

0:51:30.239 --> 0:51:33.719
<v Speaker 1>It just doesn't work that way. Uh yeah, exactly. This

0:51:33.760 --> 0:51:39.040
<v Speaker 1>woman at Columbia University named Angelo Cristiano, who was threatened

0:51:39.040 --> 0:51:45.719
<v Speaker 1>by alopecia areata, started basically this three D hair farm,

0:51:45.800 --> 0:51:49.680
<v Speaker 1>creating these printed molds that mimic the underside the internal

0:51:49.680 --> 0:51:53.640
<v Speaker 1>structure of a scalp, so she growth these sounds so gross,

0:51:53.680 --> 0:51:56.200
<v Speaker 1>but grow these little hair fields that I was kind

0:51:56.200 --> 0:51:59.640
<v Speaker 1>of talking about with Bezos. Yeah, because here's the thing, like,

0:51:59.680 --> 0:52:03.080
<v Speaker 1>if you are already bald, you don't have any donor

0:52:03.160 --> 0:52:08.160
<v Speaker 1>sites to get the follicular extraction from, right um. And

0:52:08.280 --> 0:52:11.439
<v Speaker 1>if you do have some, you know eventually you're gonna

0:52:11.520 --> 0:52:13.920
<v Speaker 1>start to thin that out when you're harvesting it. This

0:52:14.040 --> 0:52:18.240
<v Speaker 1>stem cell like hair farm that's grown in vitro solves

0:52:18.280 --> 0:52:21.520
<v Speaker 1>that problem. You've got all the donor follicles that you

0:52:21.600 --> 0:52:24.640
<v Speaker 1>need right there without having to take any from the head,

0:52:24.719 --> 0:52:28.480
<v Speaker 1>which is beautiful, pretty cool, And this is like this

0:52:28.560 --> 0:52:32.160
<v Speaker 1>could be the future, you know. I think it definitely

0:52:32.200 --> 0:52:35.560
<v Speaker 1>is there basically at the point where they can grow hair. Um.

0:52:35.719 --> 0:52:38.279
<v Speaker 1>They just are now trying to figure out how to

0:52:38.320 --> 0:52:41.200
<v Speaker 1>make it not wiry or pigmented the right way. And

0:52:41.440 --> 0:52:44.360
<v Speaker 1>all it seems to be is that figuring out in

0:52:44.480 --> 0:52:47.879
<v Speaker 1>more granular detail what the actual conditions are in your

0:52:47.920 --> 0:52:52.279
<v Speaker 1>hair follicle in your scalp, and then recreating that in vitra. Yeah,

0:52:52.320 --> 0:52:55.000
<v Speaker 1>and how to name it something other than a hair farm. Right,

0:52:55.600 --> 0:52:58.360
<v Speaker 1>So I think we should close with the idea. You know,

0:52:58.400 --> 0:53:01.160
<v Speaker 1>we like to talk about evolution and whether or not

0:53:01.280 --> 0:53:05.799
<v Speaker 1>something was an evolutionary adaptation to to stick around. And

0:53:05.880 --> 0:53:09.200
<v Speaker 1>you might think, if if women are always being surveyed

0:53:09.640 --> 0:53:13.080
<v Speaker 1>about attractiveness of men, and balding men ranked low on

0:53:13.120 --> 0:53:16.120
<v Speaker 1>that list, why on earth would it stick around as

0:53:16.160 --> 0:53:19.240
<v Speaker 1>an evolutionary trait. And I think it took a doctor

0:53:19.320 --> 0:53:23.160
<v Speaker 1>named Frank Muscarella to come around and say, maybe we

0:53:23.160 --> 0:53:27.360
<v Speaker 1>should ask women a lot of things attractiveness, but also

0:53:28.280 --> 0:53:30.759
<v Speaker 1>did does this guy look smart? Does he look trustworthy,

0:53:30.960 --> 0:53:32.920
<v Speaker 1>does he look approachable? Does he look like he might

0:53:32.920 --> 0:53:36.359
<v Speaker 1>be a good long term mate? And balding men did

0:53:36.440 --> 0:53:38.840
<v Speaker 1>rank lower and attractiveness, but they ranked a lot higher

0:53:38.840 --> 0:53:42.719
<v Speaker 1>in all those other areas. So that might explain why

0:53:42.719 --> 0:53:46.160
<v Speaker 1>it's stuck around as an evolutionary adaptation, even though not

0:53:46.239 --> 0:53:49.279
<v Speaker 1>everyone agrees. Yeah, and there was another study from the

0:53:49.360 --> 0:53:54.880
<v Speaker 1>University of Pennsylvania that basically said, um that, like, I

0:53:54.920 --> 0:53:58.600
<v Speaker 1>think bald men are viewed as ten percent more masculine,

0:53:59.160 --> 0:54:02.440
<v Speaker 1>m more calm, vident, stronger even and they were like,

0:54:02.480 --> 0:54:05.759
<v Speaker 1>this doesn't really jibe with what we what our understanding is,

0:54:05.800 --> 0:54:09.240
<v Speaker 1>So they got another set of photos, and they showed people,

0:54:09.680 --> 0:54:13.359
<v Speaker 1>um with a guy with hair and then digitally manipulated

0:54:13.400 --> 0:54:16.160
<v Speaker 1>without hair, so to make sure it wasn't like there

0:54:16.200 --> 0:54:18.960
<v Speaker 1>was some difference among the actual guys. That wasn't. They

0:54:18.960 --> 0:54:21.919
<v Speaker 1>were controlling for hair loss basically, and they still found

0:54:22.000 --> 0:54:24.680
<v Speaker 1>the same results. But it's like you said, they keep

0:54:24.719 --> 0:54:27.920
<v Speaker 1>trying to pigeonhole things into like what the evolutionary fitnesses

0:54:28.400 --> 0:54:30.560
<v Speaker 1>you know, um, and some people are like, just not

0:54:30.680 --> 0:54:34.560
<v Speaker 1>everything fits that that very in a neat, tidy way.

0:54:34.600 --> 0:54:38.480
<v Speaker 1>It's possible baldness is just an aberration, like it's not

0:54:38.560 --> 0:54:40.719
<v Speaker 1>something we're supposed to do. But it had nothing to

0:54:40.760 --> 0:54:45.120
<v Speaker 1>do with with um helping the species along or holding

0:54:45.120 --> 0:54:49.640
<v Speaker 1>it back. You know. That's right? You got anything else? No,

0:54:49.840 --> 0:54:53.600
<v Speaker 1>I hope we've displayed the proper sensitivities here. Uh. If

0:54:53.640 --> 0:54:56.560
<v Speaker 1>anyone is suffering from hair loss, then it can be

0:54:56.600 --> 0:54:58.600
<v Speaker 1>a tough thing and and handle it the best way,

0:54:58.640 --> 0:55:03.600
<v Speaker 1>you know how? Yeah, greed um. And since Chuck said

0:55:03.680 --> 0:55:06.319
<v Speaker 1>the best way, you know how, I think it's time

0:55:06.320 --> 0:55:11.680
<v Speaker 1>for a listener mail. It is. This is believe it

0:55:11.800 --> 0:55:15.960
<v Speaker 1>or not. Sammy Davis Junior enters the picture and this

0:55:16.000 --> 0:55:18.359
<v Speaker 1>is from Molly. She says, I recently found out at

0:55:18.400 --> 0:55:21.560
<v Speaker 1>a distant but kind of wild Sammy Davis Junior connection.

0:55:22.040 --> 0:55:25.440
<v Speaker 1>Turns out, my great great great aunt is the one

0:55:25.440 --> 0:55:28.720
<v Speaker 1>who caused the car accident that called Sammy Davis Junior

0:55:28.719 --> 0:55:31.279
<v Speaker 1>to lose his eye. Oh my gosh. Her name was

0:55:31.320 --> 0:55:33.360
<v Speaker 1>Helen Boss. She was seventy two when she stopped in

0:55:33.360 --> 0:55:36.000
<v Speaker 1>the middle of the highway in California and started to

0:55:36.040 --> 0:55:38.520
<v Speaker 1>reverse because she missed her exit and caused the infamous

0:55:38.520 --> 0:55:41.520
<v Speaker 1>car wreck. She missed her exit and was lost because

0:55:41.560 --> 0:55:43.920
<v Speaker 1>she was from Akron, Ohio, and had just done a

0:55:43.920 --> 0:55:46.799
<v Speaker 1>cross country road trip to California. She says to my

0:55:46.800 --> 0:55:49.760
<v Speaker 1>whole family is from the Cleveland Acron area. Shout out Ohio,

0:55:50.000 --> 0:55:52.840
<v Speaker 1>Molly Minus, my wife says as well. So there was

0:55:52.880 --> 0:55:54.839
<v Speaker 1>another woman in the car with her that had been

0:55:54.880 --> 0:55:58.560
<v Speaker 1>taking turns driving. They both suffered from injuries some injuries

0:55:58.560 --> 0:56:00.880
<v Speaker 1>as well, and there were some suits flying from all

0:56:00.920 --> 0:56:03.759
<v Speaker 1>parties supposed to accident. I believe Sammy was cleared of

0:56:03.760 --> 0:56:07.879
<v Speaker 1>any wrongdoing, even though he rear ended them. Uh. This

0:56:07.920 --> 0:56:10.040
<v Speaker 1>isn't really a proud family moment, but when my mom

0:56:10.080 --> 0:56:11.760
<v Speaker 1>told me the story, I thought it was pretty interesting.

0:56:12.239 --> 0:56:14.919
<v Speaker 1>I love the podcast I'm a tax accountant. I wanted

0:56:14.960 --> 0:56:17.040
<v Speaker 1>to say there's at least one person that absolutely loves

0:56:17.040 --> 0:56:20.279
<v Speaker 1>when you cover tax and financial topics. That is from

0:56:20.360 --> 0:56:24.200
<v Speaker 1>Molly B. Nice work. Molly, appreciate that. That is a

0:56:24.480 --> 0:56:28.959
<v Speaker 1>Rando family history if I've ever heard one, it's good.

0:56:29.400 --> 0:56:33.040
<v Speaker 1>I agree, totally interesting. If you've got some weird part

0:56:33.120 --> 0:56:35.400
<v Speaker 1>of your family history that you want to share with us,

0:56:35.480 --> 0:56:37.440
<v Speaker 1>we'd love to hear it. You can send it in

0:56:37.520 --> 0:56:45.920
<v Speaker 1>an email to Stuff podcast at i heart radio dot com.

0:56:45.960 --> 0:56:48.280
<v Speaker 1>Stuff you Should Know is a production of I Heart Radio.

0:56:48.800 --> 0:56:51.319
<v Speaker 1>For more podcasts my heart Radio, visit the i heart

0:56:51.360 --> 0:56:54.279
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0:56:54.320 --> 0:56:55.040
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