1 00:00:01,920 --> 00:00:06,480 Speaker 1: Welcome to brain Stuff production of I Heart Radio. Hey 2 00:00:06,519 --> 00:00:09,160 Speaker 1: brain Stuff, Lauren Vogel Bomb here with a classic brain 3 00:00:09,160 --> 00:00:13,600 Speaker 1: Stuff episode for you. Some beauty sector experts are predicting 4 00:00:13,640 --> 00:00:16,480 Speaker 1: that the United States is heading toward post COVID boom 5 00:00:16,520 --> 00:00:21,119 Speaker 1: and elective treatments like botox. So today let's explore the 6 00:00:21,200 --> 00:00:24,079 Speaker 1: weird history of this treatment and what it has to 7 00:00:24,120 --> 00:00:29,960 Speaker 1: do with toxic sausage. Hey brain Stuff, Lauren vogel Bomb here. 8 00:00:30,480 --> 00:00:33,279 Speaker 1: Do you have brown lines crow's feet? Now you can 9 00:00:33,360 --> 00:00:37,240 Speaker 1: make them disappear with the blink of a injection. Botox 10 00:00:37,320 --> 00:00:40,800 Speaker 1: has become a popular cosmetic treatment. And while it's pretty 11 00:00:40,800 --> 00:00:43,440 Speaker 1: common knowledge at this point that botox works thanks to 12 00:00:43,520 --> 00:00:46,959 Speaker 1: a carefully controlled toxin, what's less well known is that 13 00:00:47,040 --> 00:00:49,440 Speaker 1: we know about that toxin thanks to a batch of 14 00:00:49,560 --> 00:00:53,199 Speaker 1: killer sausages. In the early eighteen hundreds, it was this 15 00:00:53,360 --> 00:00:57,080 Speaker 1: perfectly poisonous tube pork medley that justin this Kerner, a 16 00:00:57,160 --> 00:01:00,840 Speaker 1: German physician, first suspected as the source of the potentially 17 00:01:00,920 --> 00:01:06,720 Speaker 1: deadly muscle relaxing bochulinum toxin. Sausage of questionable freshness was 18 00:01:06,760 --> 00:01:10,080 Speaker 1: not uncommon in turn of the nineteenth century Germany, but 19 00:01:10,400 --> 00:01:14,319 Speaker 1: after mysterious outbreaks of sausage poisoning during the Napoleonic Wars 20 00:01:14,360 --> 00:01:17,840 Speaker 1: repeatedly killed scores of people. Kerner got wise to the 21 00:01:17,880 --> 00:01:21,960 Speaker 1: cause after rigorous testing of hundreds of sausages and self 22 00:01:22,000 --> 00:01:25,440 Speaker 1: injections of the suspected toxin. He became the first to 23 00:01:25,480 --> 00:01:28,760 Speaker 1: identify and publish a clinical description of the toxin and 24 00:01:28,840 --> 00:01:32,160 Speaker 1: its effects. Food born botuli is um is caused when 25 00:01:32,240 --> 00:01:35,320 Speaker 1: the things we eat are infected with spores of Claustrodium 26 00:01:35,360 --> 00:01:39,800 Speaker 1: bachu linum microbes, a nearly bulletproof bacteria commonly found in 27 00:01:39,880 --> 00:01:43,600 Speaker 1: soil around the globe. When the microbe contaminates meat and 28 00:01:43,720 --> 00:01:48,320 Speaker 1: occasionally produced, it flourishes provided the environment is oxygen depleted. 29 00:01:48,840 --> 00:01:52,080 Speaker 1: This makes it the perfect deadly pairing with poorly preserved 30 00:01:52,120 --> 00:01:55,960 Speaker 1: foods and salted meats. Bachu linum toxin in the wild 31 00:01:56,040 --> 00:02:01,240 Speaker 1: can cause vision problems, difficulties swallowing, vomiting, and severely weakened muscles, 32 00:02:01,240 --> 00:02:03,800 Speaker 1: but people are so resourceful that they've figured out a 33 00:02:03,800 --> 00:02:06,720 Speaker 1: way to harness the toxin and focus its effects in 34 00:02:06,800 --> 00:02:10,520 Speaker 1: specific ways. Case in point the popularity of a wrinkle 35 00:02:10,639 --> 00:02:13,480 Speaker 1: raising serum known by the brand name botox. The use 36 00:02:13,480 --> 00:02:16,120 Speaker 1: of which has jumped by more than seven percent since 37 00:02:16,160 --> 00:02:18,880 Speaker 1: the year two thousand, according to the American Society of 38 00:02:18,919 --> 00:02:23,919 Speaker 1: Plastic Surgeons, and this increase only reflects cosmetic use. Botulinum 39 00:02:24,000 --> 00:02:26,720 Speaker 1: toxin is quite useful for a range of medical maladies, 40 00:02:26,919 --> 00:02:30,440 Speaker 1: including excessive sweating and migraines, and it can also relax 41 00:02:30,480 --> 00:02:34,200 Speaker 1: the perpetually contracted muscles of people who have cerebral palsy. 42 00:02:34,440 --> 00:02:37,480 Speaker 1: The art of looking good, just like botulinum toxin, has 43 00:02:37,520 --> 00:02:41,440 Speaker 1: a long and dubious history. Ancient Egyptians painted their eyelids 44 00:02:41,440 --> 00:02:44,080 Speaker 1: with a toxic cocktail of copper or in lead, and 45 00:02:44,200 --> 00:02:48,400 Speaker 1: the exposure lead to insomnia and brain damage. Greeks smeared 46 00:02:48,440 --> 00:02:51,880 Speaker 1: their faces with a lead based cream, which eventually caused madness. 47 00:02:52,560 --> 00:02:55,360 Speaker 1: Going to these great lengths may seem a bit ridiculous, 48 00:02:55,480 --> 00:02:58,880 Speaker 1: especially when one considers sacrificing health for beauty, but it's 49 00:02:58,919 --> 00:03:01,600 Speaker 1: not as far removed as you may think. We still 50 00:03:01,720 --> 00:03:04,760 Speaker 1: use mercury and some eye cosmetics as a preservative, all 51 00:03:04,800 --> 00:03:07,520 Speaker 1: though some states have banned the element, and in the 52 00:03:07,600 --> 00:03:10,639 Speaker 1: U two thousand, one third of thirty three red lipsticks 53 00:03:10,639 --> 00:03:13,760 Speaker 1: examined by a Safe Cosmetics advocacy group were found to 54 00:03:13,800 --> 00:03:17,679 Speaker 1: contain lead. As of sixteen, the US Food and Drug 55 00:03:17,680 --> 00:03:20,720 Speaker 1: Administration doesn't have a set limit for lead in cosmetics. 56 00:03:21,480 --> 00:03:23,960 Speaker 1: We do have a set of standards for commercial cure 57 00:03:23,960 --> 00:03:27,639 Speaker 1: to meat production, however, making most cases of botulinum toxin 58 00:03:27,720 --> 00:03:30,959 Speaker 1: poisoning a thing of the past. Though, just to be safe, 59 00:03:31,120 --> 00:03:34,120 Speaker 1: avoid any canned food that's bulging outward or that has 60 00:03:34,160 --> 00:03:36,680 Speaker 1: a dent along one of the cans seams, and don't 61 00:03:36,680 --> 00:03:39,160 Speaker 1: give honey to babies under one year of age. Yep, 62 00:03:39,560 --> 00:03:50,400 Speaker 1: that is a botulism safety precaution to Today's episode was 63 00:03:50,440 --> 00:03:52,800 Speaker 1: originally produced by Tristan McNeil and is based on the 64 00:03:52,880 --> 00:03:57,200 Speaker 1: article Ridiculous History Toxic German sausages are responsible for botox 65 00:03:57,280 --> 00:03:59,880 Speaker 1: on how stuff works dot com, written by Laurie L. Dave. 66 00:04:00,640 --> 00:04:02,920 Speaker 1: Brain Stuff is production of I Heart Radio in partnership 67 00:04:02,960 --> 00:04:04,800 Speaker 1: with how stuff works dot Com and it's produced by 68 00:04:04,800 --> 00:04:08,080 Speaker 1: Tyler Klang. Or more podcasts from my heart Radio, visit 69 00:04:08,120 --> 00:04:10,680 Speaker 1: the I heart Radio app, Apple Podcasts, or wherever you 70 00:04:10,720 --> 00:04:11,880 Speaker 1: listen to your favorite show.