1 00:00:01,120 --> 00:00:03,560 Speaker 1: Welcome to Stuff You Should Know, a production of five 2 00:00:03,600 --> 00:00:12,640 Speaker 1: Heart Radios How Stuff Works. Hey, and welcome to the podcast. 3 00:00:12,680 --> 00:00:15,480 Speaker 1: I'm Josh Clark. There's Charles W. Chuck Bryan over there, 4 00:00:16,239 --> 00:00:19,000 Speaker 1: and Jerry's out there running around somewhere. We just gave 5 00:00:19,000 --> 00:00:22,040 Speaker 1: her a hot foot. It's hilarious. Uh, and this is 6 00:00:22,079 --> 00:00:28,520 Speaker 1: stuff you should not tried. Are continuing exploration of pain? Mhm. 7 00:00:29,400 --> 00:00:31,760 Speaker 1: What else have we talked about with paint? We did 8 00:00:31,760 --> 00:00:34,519 Speaker 1: one on the pain scales, okay a couple of years ago, 9 00:00:34,680 --> 00:00:39,760 Speaker 1: and uh, then we did one on something about perceiving pain. Well, 10 00:00:39,800 --> 00:00:43,920 Speaker 1: this one, this one, this is just totally stuff you 11 00:00:43,960 --> 00:00:45,720 Speaker 1: should know them because we did a bunch of like 12 00:00:45,800 --> 00:00:47,840 Speaker 1: more niche stuff and now we're going back and doing 13 00:00:47,880 --> 00:00:53,840 Speaker 1: like the umbrella topic and we're talking about pain, which, Um, 14 00:00:53,920 --> 00:01:00,520 Speaker 1: is there a super ancient old evolutionary Um, right, I 15 00:01:00,560 --> 00:01:05,040 Speaker 1: guess that's shared basically throughout all living things. I would 16 00:01:05,080 --> 00:01:08,680 Speaker 1: say it's a pretty fair guess. I think so, Yeah, 17 00:01:08,720 --> 00:01:12,760 Speaker 1: because um, there's something that pain pain specifically, which is this. 18 00:01:13,120 --> 00:01:15,319 Speaker 1: We'll get into defining it and how hard that is 19 00:01:15,319 --> 00:01:18,959 Speaker 1: in a second, but um, it seems to be a 20 00:01:18,959 --> 00:01:24,919 Speaker 1: a fairly universal, almost universal process where our body says, hey, 21 00:01:24,959 --> 00:01:28,360 Speaker 1: there's something really bad going on, say on your hand, 22 00:01:28,640 --> 00:01:30,600 Speaker 1: So move your hand away from wherever it is in 23 00:01:30,680 --> 00:01:33,560 Speaker 1: space right now, and hopefully that will help keep it 24 00:01:33,600 --> 00:01:38,720 Speaker 1: from getting further damage. Like pain is a signal saying, um, 25 00:01:39,040 --> 00:01:41,880 Speaker 1: do something, dummy, move and it's it. I mean, that's 26 00:01:41,959 --> 00:01:44,479 Speaker 1: that's you know, you see it in and basically any 27 00:01:44,480 --> 00:01:48,440 Speaker 1: animal we've ever encountered, including the beaver and the porcupine. 28 00:01:49,040 --> 00:01:51,320 Speaker 1: That's right. And by the way, we did other people 29 00:01:51,360 --> 00:01:56,160 Speaker 1: who can't feel pain ten years ago. Yeah, it actually 30 00:01:56,200 --> 00:01:59,120 Speaker 1: seems longer ago than that. That's funny because I thought 31 00:01:59,120 --> 00:02:02,960 Speaker 1: pain Scales was forever ago and it was so Yeah, 32 00:02:03,240 --> 00:02:06,480 Speaker 1: I have no sense of time anymore. So, so we 33 00:02:06,520 --> 00:02:08,600 Speaker 1: are talking about pain, Chuck, you feel pain right or 34 00:02:08,639 --> 00:02:11,800 Speaker 1: do you have a high pain threshold? Are you sensitive? Uh? Well, 35 00:02:11,880 --> 00:02:13,399 Speaker 1: you know it's funny because I went back and listen 36 00:02:13,440 --> 00:02:15,280 Speaker 1: to the Pain Scales and I kind of chatted about 37 00:02:15,320 --> 00:02:18,040 Speaker 1: that for a bit. But I have a pretty high 38 00:02:18,040 --> 00:02:24,760 Speaker 1: pain threshold. Yeah, okay, I would say mine's average. Let's 39 00:02:24,760 --> 00:02:26,359 Speaker 1: just go with that. I wonder what I said in 40 00:02:26,400 --> 00:02:29,160 Speaker 1: the Pain Scales app because there's no way I didn't 41 00:02:29,200 --> 00:02:33,080 Speaker 1: respond to your your thing you know it will be 42 00:02:33,080 --> 00:02:37,960 Speaker 1: a mystery. So um. Apparently pain is the most common 43 00:02:38,000 --> 00:02:43,160 Speaker 1: reason that people, um go seek medical attention. But when 44 00:02:43,160 --> 00:02:45,239 Speaker 1: they go seek medical attention, as we talked about in 45 00:02:45,240 --> 00:02:47,280 Speaker 1: the pain Scales episode, the whole reason there is such 46 00:02:47,280 --> 00:02:49,600 Speaker 1: a thing as a pain scale is because it's a 47 00:02:49,680 --> 00:02:55,360 Speaker 1: fully subjective experience and it's really difficult to describe. And 48 00:02:55,400 --> 00:02:58,120 Speaker 1: it's taken medicine, like many, many years to get to 49 00:02:58,160 --> 00:03:02,880 Speaker 1: a point where they tell the people their training, doctors 50 00:03:02,880 --> 00:03:06,840 Speaker 1: and nurse practitioners and medical staff, like, if somebody tells 51 00:03:06,840 --> 00:03:09,800 Speaker 1: you they're in pain, they're experiencing pain, you have to 52 00:03:09,840 --> 00:03:13,120 Speaker 1: take them at their word. Um. And that's actually kind 53 00:03:13,160 --> 00:03:15,720 Speaker 1: of a new development because there are plenty of times 54 00:03:15,720 --> 00:03:18,960 Speaker 1: when it appears that there's absolutely nothing wrong and that 55 00:03:19,040 --> 00:03:22,080 Speaker 1: the person shouldn't be in pain. And for years doctors 56 00:03:22,120 --> 00:03:26,160 Speaker 1: just kind of treated people like like that like kooks 57 00:03:26,800 --> 00:03:28,919 Speaker 1: and didn't believe them, which was very sad. And now 58 00:03:28,919 --> 00:03:31,640 Speaker 1: we're finally figuring out there's situations where you can be 59 00:03:31,680 --> 00:03:34,360 Speaker 1: experiencing pain even though there's no reason for you to 60 00:03:34,400 --> 00:03:38,360 Speaker 1: be experiencing pain, which really underscores just how subjective it is. 61 00:03:38,880 --> 00:03:42,280 Speaker 1: That's right. Uh. In three, there was an actual definition 62 00:03:43,000 --> 00:03:45,600 Speaker 1: for pain that was introduced that has a couple of 63 00:03:45,640 --> 00:03:48,760 Speaker 1: really important caveats that will kind of play out through 64 00:03:48,760 --> 00:03:54,000 Speaker 1: this episode. Pain is an unpleasant, sensory and emotional experience. 65 00:03:54,120 --> 00:03:57,960 Speaker 1: There's the first caveat associated with actual or potential tissue 66 00:03:58,040 --> 00:04:03,000 Speaker 1: damage or described in terms of such damage, which is 67 00:04:03,040 --> 00:04:06,760 Speaker 1: a big caveat there, because you can walk into a 68 00:04:06,840 --> 00:04:11,000 Speaker 1: doctor's office and say, I've got some big time tissue damage. Doc, 69 00:04:11,640 --> 00:04:13,840 Speaker 1: I'm experiencing big time pain, and they can look you 70 00:04:13,840 --> 00:04:16,440 Speaker 1: over and be like, this guy didn't have any tissue 71 00:04:16,480 --> 00:04:20,000 Speaker 1: damage at all. So that's in the actual definition of 72 00:04:20,040 --> 00:04:22,720 Speaker 1: pain of pain. So I think that the reason they 73 00:04:22,720 --> 00:04:27,000 Speaker 1: caveatted that was for the very simple reason that pain 74 00:04:28,160 --> 00:04:32,040 Speaker 1: can be emotional. And I don't mean like real emotional pain. 75 00:04:32,080 --> 00:04:35,200 Speaker 1: I mean a physical pain that is may be made 76 00:04:35,240 --> 00:04:39,680 Speaker 1: worse by emotion or brought on by emotion, or that 77 00:04:39,760 --> 00:04:42,159 Speaker 1: you're you know, you really don't have a pain, like 78 00:04:42,160 --> 00:04:45,320 Speaker 1: you've got a chronic pain, let's say, but nothing's going 79 00:04:45,360 --> 00:04:47,880 Speaker 1: on under the hood to cause it. Yeah, And like 80 00:04:48,520 --> 00:04:51,240 Speaker 1: we've learned so much about pain since nineteen seventy three 81 00:04:51,240 --> 00:04:54,800 Speaker 1: that I saw that just this past July, um the 82 00:04:54,880 --> 00:04:58,360 Speaker 1: International Association for the Study of Pain updated and revised 83 00:04:58,360 --> 00:05:01,080 Speaker 1: their their definition. It's still basically the same, but they've 84 00:05:01,120 --> 00:05:03,360 Speaker 1: included a lot of stuff that we talk we're going 85 00:05:03,400 --> 00:05:05,920 Speaker 1: to talk about in this episode. Does it say pain 86 00:05:06,200 --> 00:05:14,640 Speaker 1: whatever you say, dude, right yea, they said pain is uh, yeah, 87 00:05:14,960 --> 00:05:18,240 Speaker 1: it is so far at least. Um. There's a bunch 88 00:05:18,240 --> 00:05:21,080 Speaker 1: of different types of pain, though actually not that many, 89 00:05:21,240 --> 00:05:26,719 Speaker 1: but there's a few. Acute pain, which is very short lasting. 90 00:05:26,760 --> 00:05:29,400 Speaker 1: If you if you put your finger on the burner 91 00:05:29,400 --> 00:05:32,240 Speaker 1: of the stove or something like that, or um, slam 92 00:05:32,240 --> 00:05:34,239 Speaker 1: it in a window, that's going to be an acute 93 00:05:34,279 --> 00:05:37,960 Speaker 1: pain where you know it's really helpful, so you know 94 00:05:38,080 --> 00:05:40,240 Speaker 1: your body is gonna say, wait a minute, that's super hot. 95 00:05:40,839 --> 00:05:42,760 Speaker 1: Or by the way, dummy, you just put your finger 96 00:05:42,800 --> 00:05:46,520 Speaker 1: in a window and you immediately have a reaction to 97 00:05:46,560 --> 00:05:50,240 Speaker 1: stop that immediate acute thing from happening, even though the 98 00:05:50,240 --> 00:05:52,760 Speaker 1: pain is gonna still be there. It's not like you 99 00:05:52,760 --> 00:05:55,640 Speaker 1: slam your finger in the window, yank your thing away 100 00:05:55,640 --> 00:05:57,880 Speaker 1: and shake it a little bit and it's gone. Right. Well, 101 00:05:57,880 --> 00:05:59,640 Speaker 1: it can be depending on the level of pain, but 102 00:05:59,680 --> 00:06:01,960 Speaker 1: it makes sense that it would still linger even in 103 00:06:02,040 --> 00:06:04,200 Speaker 1: acute paint, which from what I can tell, is like 104 00:06:04,560 --> 00:06:06,919 Speaker 1: the ideal version of pain. It's, like you said, it 105 00:06:06,960 --> 00:06:09,320 Speaker 1: makes you stop doing whatever you're doing, but the fact 106 00:06:09,360 --> 00:06:11,800 Speaker 1: that it still hangs around for another minute, it's almost 107 00:06:11,839 --> 00:06:14,159 Speaker 1: like it's teaching you a lesson, like not only stop 108 00:06:14,240 --> 00:06:17,600 Speaker 1: doing that, don't do that again. Yeah, and there's some 109 00:06:17,680 --> 00:06:20,080 Speaker 1: overlap in these, by the way, So when we talk 110 00:06:20,120 --> 00:06:24,040 Speaker 1: about the next one, no susceptive pain, this comes about 111 00:06:24,080 --> 00:06:28,080 Speaker 1: from tissue damage, like real tissue damaged by like physical 112 00:06:28,160 --> 00:06:31,320 Speaker 1: or a chemical agent. We're talking a chemical burn, or 113 00:06:31,360 --> 00:06:34,920 Speaker 1: a trauma or a surgery. This can also include slamming 114 00:06:34,960 --> 00:06:38,240 Speaker 1: that finger in the window. It can also include you 115 00:06:38,320 --> 00:06:40,120 Speaker 1: worked out really hard the day before and you're really 116 00:06:40,160 --> 00:06:42,640 Speaker 1: sore the next day. Yeah, as long as there's some 117 00:06:42,680 --> 00:06:47,479 Speaker 1: sort of like mechanical reason or some sort of damage 118 00:06:47,520 --> 00:06:50,640 Speaker 1: to tissue, or even temporary damage like a sore sore muscle. 119 00:06:51,040 --> 00:06:54,039 Speaker 1: Um And it also includes malignant pain, which is cancer pain, 120 00:06:54,320 --> 00:06:58,159 Speaker 1: which is where tumor starts growing in your tissue, impresses 121 00:06:58,200 --> 00:07:00,920 Speaker 1: on nerves and blood vessels and create pain like that. 122 00:07:01,440 --> 00:07:04,200 Speaker 1: And no, no susceptive pain is what most people think 123 00:07:04,240 --> 00:07:07,320 Speaker 1: of when they think about pain. Um And it can 124 00:07:07,360 --> 00:07:10,680 Speaker 1: be both acute and chronic. But I guess the best 125 00:07:10,720 --> 00:07:13,040 Speaker 1: way to kind of differentiate no susceptive pain from the 126 00:07:13,080 --> 00:07:16,840 Speaker 1: rest of it, there's actually something going on that is 127 00:07:16,920 --> 00:07:21,120 Speaker 1: causing the pain signal to be created. Um And it, 128 00:07:21,400 --> 00:07:24,600 Speaker 1: like I said, it can be short lasting or long lasting. Um. 129 00:07:24,640 --> 00:07:28,640 Speaker 1: And it's different from a different type of pain, appropriately 130 00:07:28,760 --> 00:07:33,520 Speaker 1: enough called neuropathic pain. Whereas no susceptive arise from arises 131 00:07:33,520 --> 00:07:38,360 Speaker 1: from tissue damage, neuropathic arises from damage to the actual 132 00:07:38,480 --> 00:07:41,640 Speaker 1: nerves themselves. Yeah. Like, uh, I don't know if you 133 00:07:41,640 --> 00:07:44,360 Speaker 1: remember this story from almost a year ago. It was 134 00:07:44,440 --> 00:07:48,440 Speaker 1: last October when I hit my shin on my bed 135 00:07:48,840 --> 00:07:52,960 Speaker 1: so hard that water started leaking out of my eyes. 136 00:07:54,000 --> 00:07:57,640 Speaker 1: I wasn't crying, it was just literally water coming out 137 00:07:57,640 --> 00:08:00,360 Speaker 1: of my eyes. And I've never felt pain like that before. 138 00:08:00,400 --> 00:08:03,720 Speaker 1: And it was clearly some kind of literal nerve damage 139 00:08:03,760 --> 00:08:07,520 Speaker 1: because for three or four months, I had like a 140 00:08:07,600 --> 00:08:10,920 Speaker 1: three uh three inch by three inch square on my 141 00:08:10,960 --> 00:08:14,680 Speaker 1: shin that was completely numb. And uh, it's it's the 142 00:08:14,720 --> 00:08:17,600 Speaker 1: worst pain, like physical pain I've ever felt in my life. 143 00:08:17,880 --> 00:08:20,520 Speaker 1: They I mean, that would definitely qualifies neuropathic pain. You 144 00:08:20,600 --> 00:08:23,840 Speaker 1: clearly messed up the nerves in that little area. UM, 145 00:08:23,920 --> 00:08:26,360 Speaker 1: and you're lucky that it only lasted three months, because 146 00:08:26,360 --> 00:08:29,520 Speaker 1: apparently neuropathic pain, which can include everything from hitting your 147 00:08:29,520 --> 00:08:33,160 Speaker 1: shin to banging your funny bone, your elbow UM two 148 00:08:33,200 --> 00:08:38,160 Speaker 1: things like sciatica or even multiple sclerosis. Anytime the neurons 149 00:08:38,200 --> 00:08:42,880 Speaker 1: in your nerve fibers are are damaged. UM, that's neuropathic pain, 150 00:08:43,080 --> 00:08:45,760 Speaker 1: and it can last. It can very easily translate from 151 00:08:45,800 --> 00:08:48,800 Speaker 1: acute pain over to chronic pain, which is pain that 152 00:08:48,880 --> 00:08:52,640 Speaker 1: last six months or longer um, which can itself be 153 00:08:52,679 --> 00:08:57,480 Speaker 1: no susceptive or neuropathic. Uh. It can also, unfortunately be psychogenic. 154 00:08:57,600 --> 00:09:02,240 Speaker 1: Chronic pain can be, which is where you have lasting, uh, 155 00:09:02,600 --> 00:09:06,679 Speaker 1: sustained pain over six months or longer um for no 156 00:09:06,760 --> 00:09:10,520 Speaker 1: good reason whatsoever. Yeah, and this is you know, it 157 00:09:10,520 --> 00:09:14,120 Speaker 1: gets really sort of murky and confusing. Here. We are 158 00:09:14,200 --> 00:09:16,400 Speaker 1: not saying that chronic pain is all in your head, 159 00:09:17,040 --> 00:09:20,880 Speaker 1: but we're saying that in some cases that there there 160 00:09:20,960 --> 00:09:24,360 Speaker 1: is no reason behind you continuing to feel chronic pain. 161 00:09:25,520 --> 00:09:28,160 Speaker 1: But so many people suffer from chronic pain. I think 162 00:09:28,760 --> 00:09:31,280 Speaker 1: roughly it kind of varies, you know, depending on the year. 163 00:09:31,320 --> 00:09:36,280 Speaker 1: But somewhere in the neighborhood of twenty adult Americans suffer 164 00:09:36,360 --> 00:09:41,680 Speaker 1: chronic pain every single year. Um, And it's when you 165 00:09:41,679 --> 00:09:44,920 Speaker 1: hear people talk about that, like, uh, I just feel 166 00:09:44,920 --> 00:09:46,480 Speaker 1: bad for him. I can't imagine what it's like to 167 00:09:46,520 --> 00:09:49,520 Speaker 1: walk around in constant pain, and it's probably even more 168 00:09:49,559 --> 00:09:54,080 Speaker 1: frustrating when a doctor can't trace it to a thing like, hey, 169 00:09:54,160 --> 00:09:57,400 Speaker 1: we fixed that. It shouldn't be hurting anymore, right, especially 170 00:09:57,400 --> 00:10:00,600 Speaker 1: if they're being patronizing and treating you like your cook, Well, 171 00:10:00,840 --> 00:10:03,959 Speaker 1: that's a bad doctor. You should not go. Sure, But again, 172 00:10:04,000 --> 00:10:07,240 Speaker 1: I mean, like I feel like people with fibromyalgia or 173 00:10:07,320 --> 00:10:09,679 Speaker 1: chronic fatigue. I don't know if you experience pain with 174 00:10:09,760 --> 00:10:12,839 Speaker 1: chronic fatigue, but have long been treated like their nuts, 175 00:10:12,880 --> 00:10:15,120 Speaker 1: like it's all in their heads, just because you know, 176 00:10:15,360 --> 00:10:17,800 Speaker 1: science has not been able to identify exactly what the 177 00:10:17,800 --> 00:10:21,200 Speaker 1: deal is. Yeah, I would say, if your doctor is 178 00:10:21,240 --> 00:10:23,440 Speaker 1: like that, go to a doctor with a little better 179 00:10:23,480 --> 00:10:26,200 Speaker 1: bedside manner. At least they might be saying the same thing. 180 00:10:26,760 --> 00:10:30,079 Speaker 1: But they would should treat you with respect. And if 181 00:10:30,280 --> 00:10:33,280 Speaker 1: if they're wearing oversized clown shoes, so much the better. 182 00:10:33,559 --> 00:10:35,960 Speaker 1: That's usually it did give way for a great doctor, 183 00:10:36,520 --> 00:10:40,360 Speaker 1: that's right. Um, I don't think we said that, uh, 184 00:10:40,600 --> 00:10:43,880 Speaker 1: we we talked about no susceptive pain, but no susception 185 00:10:43,960 --> 00:10:48,439 Speaker 1: is taken from the Latin word for hurt, and um 186 00:10:48,559 --> 00:10:51,600 Speaker 1: pain is its own thing like pain perception. We're talking 187 00:10:51,640 --> 00:10:54,880 Speaker 1: about what's going on with the central nervous system, uh 188 00:10:55,320 --> 00:10:59,240 Speaker 1: the peripheral central nervous system as well, and how it 189 00:10:59,320 --> 00:11:06,560 Speaker 1: processes this information is really uh interesting and still cloudy 190 00:11:06,600 --> 00:11:09,840 Speaker 1: because the brain is involved. And we've done dozens and 191 00:11:09,880 --> 00:11:12,240 Speaker 1: dozens of podcasts that involved the brain, and at some 192 00:11:12,280 --> 00:11:15,320 Speaker 1: point during all of them we usually say something like, 193 00:11:15,520 --> 00:11:17,319 Speaker 1: this is kind of their best guess right now, because 194 00:11:17,320 --> 00:11:20,160 Speaker 1: the brain is still such a mystery. Yeah, we have 195 00:11:20,400 --> 00:11:23,320 Speaker 1: made like advances by leaps and bounds since the sixties 196 00:11:23,360 --> 00:11:25,760 Speaker 1: when we kind of started to change our understanding of 197 00:11:25,760 --> 00:11:28,679 Speaker 1: pain and definitely refining it. But one of the things 198 00:11:28,760 --> 00:11:33,120 Speaker 1: we figured out is that no susception itself is separate 199 00:11:33,160 --> 00:11:36,680 Speaker 1: from the experience of pain. It's like the body giving 200 00:11:36,840 --> 00:11:40,559 Speaker 1: the brain information about something that's going on with your 201 00:11:40,559 --> 00:11:44,400 Speaker 1: body right now, but it's not pain itself. Pain is 202 00:11:44,520 --> 00:11:49,760 Speaker 1: the brain responding to that information, and so no susception, 203 00:11:50,040 --> 00:11:53,160 Speaker 1: as we'll see, is kind of this process where your 204 00:11:53,200 --> 00:11:57,960 Speaker 1: body um detects some sort of noxious stimuli UH, and 205 00:11:58,040 --> 00:12:00,920 Speaker 1: the no susceptors your specific kind of UM little sense 206 00:12:00,960 --> 00:12:04,400 Speaker 1: receptors that are tuned to pain. As we'll talk about UM. 207 00:12:04,480 --> 00:12:06,760 Speaker 1: They send a signal to your brain saying, hey, there's 208 00:12:06,760 --> 00:12:09,320 Speaker 1: something going on here, and then in your brain, your 209 00:12:09,320 --> 00:12:11,679 Speaker 1: your brain starts sort through the whole thing and decides 210 00:12:11,679 --> 00:12:15,560 Speaker 1: how to respond. So no susception and pain they're very 211 00:12:15,640 --> 00:12:18,400 Speaker 1: much intertwined, but they're definitely different things, and we've actually 212 00:12:18,480 --> 00:12:21,400 Speaker 1: seen that one can exist without the other. Yeah, I 213 00:12:21,400 --> 00:12:24,760 Speaker 1: mean they've done studies that UM and I. I mean 214 00:12:24,800 --> 00:12:26,600 Speaker 1: we had to have talked about this and other people 215 00:12:26,600 --> 00:12:32,640 Speaker 1: that can't feel pain UM congenital analgesia. I don't remember 216 00:12:32,679 --> 00:12:35,400 Speaker 1: ever saying those words before. I think we had to 217 00:12:35,440 --> 00:12:40,160 Speaker 1: have There's no way, although knowing us, it's possible we 218 00:12:40,240 --> 00:12:43,800 Speaker 1: walked around that one. Well maybe so. But there are studies, 219 00:12:44,160 --> 00:12:47,120 Speaker 1: including ones on that people who can't feel pain, that 220 00:12:47,200 --> 00:12:51,040 Speaker 1: have shown that no susception can occur without the experience 221 00:12:51,040 --> 00:12:54,120 Speaker 1: of pain, and UM pain can be experienced with the 222 00:12:54,160 --> 00:12:56,679 Speaker 1: absence of no susception. So it's sort of a two 223 00:12:56,720 --> 00:12:59,439 Speaker 1: way street. Yeah, that's like that psychogenic pain where you 224 00:12:59,559 --> 00:13:02,320 Speaker 1: there's no reason for you to be feeling that pain 225 00:13:02,440 --> 00:13:05,840 Speaker 1: right then, right, yeah, And because it's the brain, it's 226 00:13:05,960 --> 00:13:08,920 Speaker 1: um and you put in here it's like it sounds funny, 227 00:13:09,000 --> 00:13:12,160 Speaker 1: but your brain is what's feeling the pain. Like when 228 00:13:12,200 --> 00:13:16,640 Speaker 1: you smash that hand in a window. Um, you might 229 00:13:16,679 --> 00:13:19,360 Speaker 1: think that your hand feeling the pain, but technically it's 230 00:13:19,360 --> 00:13:22,360 Speaker 1: your brain, if that makes sense. Yeah, or even that 231 00:13:22,440 --> 00:13:26,480 Speaker 1: like you're you're that hand that window smashing your hand 232 00:13:26,840 --> 00:13:31,640 Speaker 1: set off a specific unique kind of um uh signal 233 00:13:32,080 --> 00:13:35,079 Speaker 1: that that transmits a pain signal directly your brain. Your 234 00:13:35,080 --> 00:13:38,120 Speaker 1: brain experiences the pain. That's just not quite right. That's 235 00:13:38,120 --> 00:13:44,160 Speaker 1: actually Renee des cartes interpretation of it, and can so well. 236 00:13:44,200 --> 00:13:46,000 Speaker 1: Considering he was working in the first half of the 237 00:13:46,000 --> 00:13:49,520 Speaker 1: sixteen hundreds, he wasn't that far off the mark, especially 238 00:13:49,520 --> 00:13:53,040 Speaker 1: considering that before him the Greeks had thought up basically 239 00:13:53,080 --> 00:13:55,839 Speaker 1: up to day car, everyone had thought, starting with the Greeks, 240 00:13:55,880 --> 00:13:59,080 Speaker 1: that pain was like a spirit intrusion, it was like 241 00:13:59,160 --> 00:14:01,880 Speaker 1: something external at all. And in fact, our word pain 242 00:14:02,400 --> 00:14:07,480 Speaker 1: comes from uh pena like subpoena, which means penalty. So 243 00:14:07,559 --> 00:14:11,280 Speaker 1: this like pain was considered a punishment from the gods 244 00:14:11,960 --> 00:14:13,560 Speaker 1: um And Dave Carr was like, no, I think this 245 00:14:13,640 --> 00:14:16,559 Speaker 1: is an internal process, and he had like the broad 246 00:14:16,640 --> 00:14:19,680 Speaker 1: strokes of it. It's just that he didn't have the 247 00:14:19,720 --> 00:14:22,640 Speaker 1: details that we have now today. Yeah, he kind of 248 00:14:22,680 --> 00:14:26,520 Speaker 1: got well he got one half of it pretty right. Um, 249 00:14:26,560 --> 00:14:28,680 Speaker 1: but I mentioned it was a two way street. It's 250 00:14:28,680 --> 00:14:30,720 Speaker 1: a two way street in a lot of ways. Because 251 00:14:30,760 --> 00:14:33,920 Speaker 1: what we've learned since decart is that we do have 252 00:14:33,960 --> 00:14:36,240 Speaker 1: pain signals that go up from nerves in the body 253 00:14:36,720 --> 00:14:38,680 Speaker 1: to the brain to say hey, I'm hurt. Those are 254 00:14:38,680 --> 00:14:43,040 Speaker 1: called ascending signals. But then we also have another signal 255 00:14:43,120 --> 00:14:45,440 Speaker 1: going I'm just gonna call it downstream for lack of 256 00:14:45,440 --> 00:14:49,400 Speaker 1: a better term, descending signals that come from the brain 257 00:14:49,960 --> 00:14:53,160 Speaker 1: that can kind of mute the pain or turn off 258 00:14:53,200 --> 00:14:55,920 Speaker 1: the pain signals. And that's you know, as we'll see 259 00:14:56,000 --> 00:14:58,800 Speaker 1: later when it comes to medication and stuff. It's sort 260 00:14:58,840 --> 00:15:02,360 Speaker 1: of managing that way, like whatever traffic light is on 261 00:15:02,360 --> 00:15:04,920 Speaker 1: that two way street. Yeah, well that was like a 262 00:15:05,040 --> 00:15:07,840 Speaker 1: huge thing, Chuck, like to figure out that. Wait a minute, Like, 263 00:15:07,920 --> 00:15:10,840 Speaker 1: first of all, the experience of pain is totally in 264 00:15:10,920 --> 00:15:14,400 Speaker 1: the in the brain. Right, your hand itself isn't actually hurting. 265 00:15:14,440 --> 00:15:17,200 Speaker 1: Your brain is hurt is what hurts. It just feels 266 00:15:17,200 --> 00:15:19,800 Speaker 1: like it's coming from your hand. And then secondly, the 267 00:15:19,800 --> 00:15:24,200 Speaker 1: idea that your brain can influence this the experience of pain, 268 00:15:24,560 --> 00:15:28,200 Speaker 1: that was just revolutionary. And so as a result, we've 269 00:15:28,240 --> 00:15:32,480 Speaker 1: come to kind of see pain as the brain. There's 270 00:15:32,880 --> 00:15:36,040 Speaker 1: a neuroscentist name vs. Rama Shan Droton who's just brilliant 271 00:15:36,280 --> 00:15:40,200 Speaker 1: and he um, he said that pain. This is paraphrasing him. 272 00:15:40,360 --> 00:15:43,480 Speaker 1: He said that pain is the brain's opinion of the 273 00:15:43,480 --> 00:15:46,680 Speaker 1: current state of your health. You got no pain, It's 274 00:15:46,680 --> 00:15:49,640 Speaker 1: all good. You've got pain. Your brain is interpreting there's 275 00:15:49,680 --> 00:15:51,880 Speaker 1: something wrong with like your hand or your leg, or 276 00:15:51,920 --> 00:15:55,920 Speaker 1: your guts or something like that. And it's just an opinion. 277 00:15:55,920 --> 00:15:58,360 Speaker 1: And the opinion can be gotten wrong too. Well, you 278 00:15:58,360 --> 00:16:02,560 Speaker 1: know what they say about opinions. Yeah, everybody's got an 279 00:16:02,560 --> 00:16:04,880 Speaker 1: elbow of them. All right, I think we should take 280 00:16:04,880 --> 00:16:08,320 Speaker 1: a break and we're gonna come back and dive into 281 00:16:08,400 --> 00:16:38,200 Speaker 1: some hard science right after this. Alrighty, so your brain 282 00:16:38,240 --> 00:16:41,360 Speaker 1: has an opinion about the current state of your health. Um, 283 00:16:41,440 --> 00:16:43,840 Speaker 1: we're still at the stage where we're sort of testing 284 00:16:43,840 --> 00:16:47,960 Speaker 1: out how pain is generated and how we experience it. 285 00:16:48,920 --> 00:16:51,080 Speaker 1: But what we kind of think right now is what 286 00:16:51,120 --> 00:16:54,520 Speaker 1: we mentioned a little bit earlier is that some of 287 00:16:54,560 --> 00:16:58,560 Speaker 1: the sense receptors located on the nerve endings are really 288 00:16:58,920 --> 00:17:04,440 Speaker 1: finely tuned two different kinds of UM, different kinds of pain, 289 00:17:04,480 --> 00:17:06,520 Speaker 1: but really tuned to different kinds of thing that might 290 00:17:06,600 --> 00:17:09,800 Speaker 1: cause pain, like a hot stove or a needle going 291 00:17:09,840 --> 00:17:12,040 Speaker 1: to your arm. Yeah. And you can pretty much divide 292 00:17:12,080 --> 00:17:17,960 Speaker 1: them into three categories. Mechanical which is pulling, stretching, tearing, cutting, chemical, 293 00:17:18,280 --> 00:17:21,600 Speaker 1: which say like exposure to acid or something, and then 294 00:17:21,680 --> 00:17:25,359 Speaker 1: thermal like like heat or cold. Um. And the idea 295 00:17:25,400 --> 00:17:30,040 Speaker 1: that these no susceptors are capable of being triggered by 296 00:17:30,200 --> 00:17:33,600 Speaker 1: exposure to those kind of stimuli from the external world, 297 00:17:34,000 --> 00:17:39,359 Speaker 1: that that is what kicks off the no susception process. Yeah. 298 00:17:39,480 --> 00:17:42,119 Speaker 1: And they, uh, they're all very different and they have 299 00:17:42,160 --> 00:17:45,240 Speaker 1: different ways of communicating with the brain. Um. There are 300 00:17:45,240 --> 00:17:48,639 Speaker 1: some that do things really really fast. Uh. These U 301 00:17:48,800 --> 00:17:51,240 Speaker 1: there are some called a fibers. They have a little 302 00:17:51,920 --> 00:17:54,600 Speaker 1: it's kind of like a little express train instead of 303 00:17:54,600 --> 00:17:58,320 Speaker 1: having to make stops along the way, has a fatty 304 00:17:58,480 --> 00:18:04,040 Speaker 1: mile in sheath that's going to insulate the electro conduction 305 00:18:04,080 --> 00:18:06,680 Speaker 1: basically on the wire and it really just zaps it. 306 00:18:06,720 --> 00:18:09,399 Speaker 1: They're really really fast not a lot of information losses 307 00:18:09,440 --> 00:18:14,120 Speaker 1: going on. And that's like that first really intense pain 308 00:18:14,200 --> 00:18:16,399 Speaker 1: you feel when you burn your hand or when you 309 00:18:16,440 --> 00:18:19,600 Speaker 1: slam it into the window. Is that's kind of what's 310 00:18:19,640 --> 00:18:22,040 Speaker 1: going on with the A fibers, right, And then you've 311 00:18:22,040 --> 00:18:28,399 Speaker 1: got sea fibers, which aren't insulated and they are slower conducting, 312 00:18:28,440 --> 00:18:30,760 Speaker 1: but they also have a bunch of they recruit a 313 00:18:30,800 --> 00:18:33,320 Speaker 1: bunch of them to conduct signals from different parts of 314 00:18:33,440 --> 00:18:37,320 Speaker 1: different areas um to the brain to say, hey, this 315 00:18:37,400 --> 00:18:40,399 Speaker 1: is this is actually pretty pretty problematic. We got a 316 00:18:40,400 --> 00:18:42,840 Speaker 1: real thing going on here. And they account for the 317 00:18:43,560 --> 00:18:48,320 Speaker 1: follow up like usually burning, throbbing kind of sensation that 318 00:18:48,480 --> 00:18:51,600 Speaker 1: can be followed by that first like bolt of pain 319 00:18:51,720 --> 00:18:55,480 Speaker 1: that the A fibers deliver, and then that's from the 320 00:18:55,480 --> 00:18:59,800 Speaker 1: actual like like uh no susceptors. There's other stuff that 321 00:19:00,000 --> 00:19:02,600 Speaker 1: spens to like if you cut open your hand, those 322 00:19:02,720 --> 00:19:06,320 Speaker 1: damage cells you know, spill their guts and so like 323 00:19:06,400 --> 00:19:10,560 Speaker 1: potassium and glutamate and substance peace starch start like change 324 00:19:10,640 --> 00:19:14,640 Speaker 1: start firing off, like other neurons in the area um 325 00:19:14,760 --> 00:19:17,840 Speaker 1: you might have an inflammatory response, so things like histamine 326 00:19:17,880 --> 00:19:20,760 Speaker 1: show up and they start setting off other nerve fibers too, 327 00:19:20,760 --> 00:19:25,840 Speaker 1: So it's more than just the you know, the cut hand. No, 328 00:19:26,000 --> 00:19:29,240 Speaker 1: susceptor is telling the brain that something's happening. Like a 329 00:19:29,320 --> 00:19:32,480 Speaker 1: whole bunch of different responses from the area are going 330 00:19:32,520 --> 00:19:35,240 Speaker 1: to arrive at the brain and produce this really complex, 331 00:19:35,440 --> 00:19:39,560 Speaker 1: rich message saying here's generally what's going on, and here's 332 00:19:39,600 --> 00:19:43,600 Speaker 1: how bad it is. You ever had a bad burn? Yes, man, 333 00:19:43,680 --> 00:19:46,239 Speaker 1: that's the worst. They are pretty bad. I don't even 334 00:19:46,320 --> 00:19:50,760 Speaker 1: remember what happened, but um, I definitely have burned myself 335 00:19:50,760 --> 00:19:54,000 Speaker 1: pretty bad. You may has this same spot on her 336 00:19:54,040 --> 00:19:57,359 Speaker 1: hand that she gets in like the confection of it. 337 00:19:57,520 --> 00:20:01,359 Speaker 1: Like basically every time it heals, she just re upset again. 338 00:20:01,440 --> 00:20:03,840 Speaker 1: She's always got this little little thing on like I 339 00:20:03,880 --> 00:20:05,800 Speaker 1: think it's her pinky knuckle on her right hand, and 340 00:20:05,840 --> 00:20:07,880 Speaker 1: she always like hits the same spot on the yep. 341 00:20:08,160 --> 00:20:10,960 Speaker 1: Oh man, every time you get that lady a glove 342 00:20:11,080 --> 00:20:13,479 Speaker 1: a hot myth. Yeah, I think by now it's just 343 00:20:13,520 --> 00:20:17,280 Speaker 1: so callous that she is dead. She fights sailors with 344 00:20:17,320 --> 00:20:21,600 Speaker 1: it these days. Yeah, those burns really linger. And that's 345 00:20:21,640 --> 00:20:24,240 Speaker 1: like every time I hear someone or see somebody that 346 00:20:24,760 --> 00:20:27,119 Speaker 1: has has you know, had been in a fire and 347 00:20:27,160 --> 00:20:29,440 Speaker 1: had really really bad burns over a lot of their body. 348 00:20:29,440 --> 00:20:33,639 Speaker 1: I just I can't imagine the lingering pain that they 349 00:20:33,640 --> 00:20:35,239 Speaker 1: go through. I know we've talked about this on some 350 00:20:35,320 --> 00:20:38,879 Speaker 1: episode before, but uh, just those burns that it seems 351 00:20:38,920 --> 00:20:43,000 Speaker 1: like they hurt forever. Yeah, I mean, you've got exposed 352 00:20:43,000 --> 00:20:46,120 Speaker 1: nerves fibers to just the air, which you know, as 353 00:20:46,119 --> 00:20:52,800 Speaker 1: we'll also see, when you undergo a particularly brilliant experience 354 00:20:52,800 --> 00:20:56,480 Speaker 1: of acute pain, it can be so thorough and it's 355 00:20:56,640 --> 00:21:00,480 Speaker 1: energizing of your nerves that they actually become sense of tized, 356 00:21:01,200 --> 00:21:03,679 Speaker 1: so like they become more sensitive than they would have 357 00:21:03,840 --> 00:21:07,080 Speaker 1: before that, which is actually also a problem with with 358 00:21:07,200 --> 00:21:10,600 Speaker 1: chronic pain too. But if you if you experience burns 359 00:21:10,640 --> 00:21:13,040 Speaker 1: like that deep over all of your body, not only 360 00:21:13,080 --> 00:21:16,000 Speaker 1: are you going through the normal pain, you're probably more 361 00:21:16,080 --> 00:21:19,560 Speaker 1: sensitive now to normal stuff like air blowing on your 362 00:21:19,600 --> 00:21:23,000 Speaker 1: exposed nerves than you wouldn't otherwise, and that just makes 363 00:21:23,000 --> 00:21:25,320 Speaker 1: it that much worse. Yeah. And then some things that 364 00:21:25,400 --> 00:21:29,600 Speaker 1: you might think really hurt don't hurt. Um, like cuts, 365 00:21:29,640 --> 00:21:32,000 Speaker 1: I've had cuts before that don't hurt. They might freak 366 00:21:32,040 --> 00:21:34,760 Speaker 1: you out, uh to look at it and to see, 367 00:21:35,080 --> 00:21:37,320 Speaker 1: you know, like your skin exposed and some people are 368 00:21:37,320 --> 00:21:40,080 Speaker 1: really freaked out by the blood. Um, I've had other 369 00:21:40,119 --> 00:21:42,880 Speaker 1: people I know I've never broken bones that have had 370 00:21:42,920 --> 00:21:45,280 Speaker 1: some pretty gnarly injuries like that. That said, it didn't 371 00:21:45,280 --> 00:21:49,119 Speaker 1: really hurt that much. Yeah, they're walking around like a skeleton. 372 00:21:49,160 --> 00:21:51,200 Speaker 1: You hang on the door with their arms just flopping 373 00:21:51,280 --> 00:21:53,439 Speaker 1: back and forth. It's really interesting how it all works. 374 00:21:53,640 --> 00:21:56,200 Speaker 1: But it really underscores, you know, how the brain can 375 00:21:56,200 --> 00:21:59,280 Speaker 1: get its opinion um of what's wrong with the body 376 00:21:59,320 --> 00:22:02,639 Speaker 1: based on the pain information wrong sometimes a lot of times, 377 00:22:02,840 --> 00:22:05,960 Speaker 1: like think about a hangnail. Hangnail is no threat whatsoever 378 00:22:06,000 --> 00:22:09,520 Speaker 1: to your survival, but those things hurt. Or a paper cut. 379 00:22:10,119 --> 00:22:11,919 Speaker 1: No one's going to die from a paper cut, but 380 00:22:11,960 --> 00:22:15,440 Speaker 1: it really really hurts too. Um. It can be overblown, 381 00:22:15,480 --> 00:22:17,560 Speaker 1: it can be underblown, but it really goes to show 382 00:22:17,600 --> 00:22:21,320 Speaker 1: like it's the brain taking all this different information together 383 00:22:21,400 --> 00:22:24,080 Speaker 1: and saying, here's how bad I think this is. Yeah, 384 00:22:24,119 --> 00:22:28,159 Speaker 1: it's pretty cool and painful. Uh. So let's say you 385 00:22:28,200 --> 00:22:30,920 Speaker 1: get hurt. Let's say you you slam your your hand 386 00:22:30,920 --> 00:22:33,520 Speaker 1: in the window like I was talking about, which I 387 00:22:33,560 --> 00:22:35,080 Speaker 1: think has happened. I don't know why I keep going 388 00:22:35,119 --> 00:22:39,400 Speaker 1: to that got your worst fear. I don't know, it's 389 00:22:39,520 --> 00:22:41,720 Speaker 1: I don't I don't think it's better not your worst fear. 390 00:22:41,760 --> 00:22:43,399 Speaker 1: That is not that bad. That'd be hard. It's a 391 00:22:43,440 --> 00:22:45,120 Speaker 1: lot easier to shut your hand in a car door 392 00:22:45,160 --> 00:22:48,000 Speaker 1: than a window. But O, man, that hurts either way. Yeah, man, 393 00:22:48,040 --> 00:22:49,560 Speaker 1: I had a knock wood. That hasn't happened to me 394 00:22:49,560 --> 00:22:52,040 Speaker 1: in a long time. Yeah. Every time my daughter shuts 395 00:22:52,080 --> 00:22:53,960 Speaker 1: the door, which I tried to let her do whatever 396 00:22:53,960 --> 00:22:57,080 Speaker 1: she can on her own, I'm always just like, don't 397 00:22:57,080 --> 00:23:01,119 Speaker 1: do it. Do you put ovenmits her hands first? No? No, 398 00:23:01,200 --> 00:23:04,840 Speaker 1: nanny stayed at our house. Uh. So you you get 399 00:23:04,920 --> 00:23:08,080 Speaker 1: hurt on your hand, Let's say, Um, the signal that 400 00:23:08,200 --> 00:23:11,280 Speaker 1: is gonna travel it travels through the into the gray 401 00:23:11,280 --> 00:23:13,560 Speaker 1: matter of your spinal cord, and there are gonna be 402 00:23:13,600 --> 00:23:16,600 Speaker 1: a lot of different connections made with the spinal neurons there, 403 00:23:17,080 --> 00:23:19,200 Speaker 1: and it's going to cover a broad area of the body, 404 00:23:19,320 --> 00:23:23,359 Speaker 1: which is why sometimes if you get hurt, um, especially 405 00:23:23,400 --> 00:23:26,240 Speaker 1: if it's like an internal injury, you don't know exactly 406 00:23:26,240 --> 00:23:28,720 Speaker 1: where the pain's coming from. You might tell your doctor 407 00:23:29,040 --> 00:23:31,520 Speaker 1: you just might rub around your whole torso when in 408 00:23:31,520 --> 00:23:34,480 Speaker 1: fact what's actually hurt is a fairly small area. Yeah, 409 00:23:34,680 --> 00:23:36,760 Speaker 1: or it could be like a completely different part of 410 00:23:36,800 --> 00:23:40,480 Speaker 1: your your body or kind of near. It's called referred pain, 411 00:23:40,800 --> 00:23:42,840 Speaker 1: like if you're having a heart attack, usually feel pain 412 00:23:42,880 --> 00:23:46,360 Speaker 1: in your arm. Yeah. If you have brain freeze, that's 413 00:23:46,400 --> 00:23:48,920 Speaker 1: your blood vessels on the roof of your mouth expanding 414 00:23:49,160 --> 00:23:52,280 Speaker 1: because they're cold. But you feel it unlike your forehead 415 00:23:52,359 --> 00:23:55,159 Speaker 1: really terribly, which doesn't make any sense. So yeah, I 416 00:23:55,200 --> 00:23:57,959 Speaker 1: think that's from those the nerve or the sea fiber 417 00:23:58,040 --> 00:24:01,239 Speaker 1: information where it makes it tough to also figure out 418 00:24:01,280 --> 00:24:05,879 Speaker 1: where it's coming from. Have you ever been to a cardiologist? No, 419 00:24:06,720 --> 00:24:10,439 Speaker 1: I'm going I'm going to one this week. Man. I 420 00:24:10,480 --> 00:24:12,600 Speaker 1: had I've known two people in the past like a 421 00:24:12,600 --> 00:24:14,919 Speaker 1: month that have dropped dead that are like my age. 422 00:24:15,600 --> 00:24:19,800 Speaker 1: What uh. One friend of mine from college had been 423 00:24:19,840 --> 00:24:23,800 Speaker 1: experiencing chess pains and he went to drove drove himself 424 00:24:23,760 --> 00:24:26,280 Speaker 1: to the hospital like collapse and died on the way 425 00:24:26,280 --> 00:24:29,800 Speaker 1: into the hospital. Just terrible. And I haven't been out 426 00:24:29,800 --> 00:24:32,560 Speaker 1: of touch since college, but it really hit me hard 427 00:24:32,600 --> 00:24:34,159 Speaker 1: to where I was like, you know what, I I 428 00:24:34,200 --> 00:24:35,879 Speaker 1: want to go, like just see what's going on in 429 00:24:35,920 --> 00:24:40,919 Speaker 1: there and get some preventative or not. Preventative, but just 430 00:24:40,960 --> 00:24:45,280 Speaker 1: some proactive tests done. Uh, you know where they see 431 00:24:45,280 --> 00:24:47,520 Speaker 1: how your arteries are doing. Because I've got cholesterol issues 432 00:24:47,560 --> 00:24:51,600 Speaker 1: because of my my family history and stuff, and I 433 00:24:51,600 --> 00:24:54,000 Speaker 1: wanted to be one of those things where they're like, oh, well, 434 00:24:54,000 --> 00:24:56,720 Speaker 1: it turns out that you know you were clogged this 435 00:24:56,760 --> 00:24:59,840 Speaker 1: whole time. So I don't I don't care what they say. 436 00:25:00,000 --> 00:25:03,119 Speaker 1: I'm going to demand those tests. Yeah. I think you 437 00:25:03,240 --> 00:25:06,320 Speaker 1: probably will have to pay for them out of pocket, 438 00:25:06,400 --> 00:25:08,320 Speaker 1: but that's not the end of the world. If, like 439 00:25:08,359 --> 00:25:10,720 Speaker 1: you have, you have concerns about it, no want of 440 00:25:10,800 --> 00:25:15,000 Speaker 1: genuine concerns, cardiologists might actually go ahead and prescribe it anyway. Well, 441 00:25:15,040 --> 00:25:16,720 Speaker 1: I don't have concerns in that I have chest pains 442 00:25:16,760 --> 00:25:19,240 Speaker 1: or anything, but but if you have a family history, 443 00:25:19,280 --> 00:25:21,160 Speaker 1: they may. Yeah, I just I want to know what's 444 00:25:21,200 --> 00:25:23,080 Speaker 1: going on. I'll I think that's great. And actually it's 445 00:25:23,119 --> 00:25:25,639 Speaker 1: funny like you me had suggested we do something like 446 00:25:25,680 --> 00:25:29,160 Speaker 1: that too, So maybe we'll see you at the cardiologists office. Well, 447 00:25:29,200 --> 00:25:31,280 Speaker 1: I think for women you can go get heart screenings 448 00:25:31,280 --> 00:25:35,320 Speaker 1: for women, um, very easily. Uh. And I don't know 449 00:25:35,359 --> 00:25:37,119 Speaker 1: if it's because I thought it was for both and 450 00:25:37,480 --> 00:25:38,920 Speaker 1: I talked to the lady on the phone. She said, O, 451 00:25:38,960 --> 00:25:41,440 Speaker 1: and then that's only for women. And I guess that's 452 00:25:41,480 --> 00:25:46,520 Speaker 1: because women are less likely to talk to doctors about 453 00:25:46,520 --> 00:25:49,600 Speaker 1: their heart because I think it's maybe generally thought of 454 00:25:49,640 --> 00:25:52,360 Speaker 1: as something that men experience more. Yeah, I guess now 455 00:25:52,400 --> 00:25:54,399 Speaker 1: that you say that, it does seem like more of 456 00:25:54,640 --> 00:25:56,720 Speaker 1: a man. So I think they're trying to be proactive 457 00:25:56,720 --> 00:25:59,600 Speaker 1: and saying like, hey, women, you need to think about 458 00:25:59,600 --> 00:26:01,720 Speaker 1: this stuff too, so we'll offer it's like a hundred 459 00:26:01,720 --> 00:26:04,120 Speaker 1: dollar heart screening or something like that. Gosh, is there 460 00:26:04,160 --> 00:26:09,480 Speaker 1: anything socialized medicine can't do? So, uh, we were talking 461 00:26:09,480 --> 00:26:13,400 Speaker 1: about those first um, those first set of spinal neurons. 462 00:26:13,440 --> 00:26:16,080 Speaker 1: Then you have secondary neurons that are going to send 463 00:26:16,119 --> 00:26:18,920 Speaker 1: their signals up through the white matter of the spinal cord. 464 00:26:19,560 --> 00:26:23,840 Speaker 1: And this is an expressway where all the traffic from 465 00:26:23,880 --> 00:26:27,119 Speaker 1: all of these lower segments just just speed up the 466 00:26:27,160 --> 00:26:30,840 Speaker 1: spinal cord. Yeah yeah, which is you know, normal for 467 00:26:30,880 --> 00:26:34,040 Speaker 1: any kind of sensory information. But um, the pain, the 468 00:26:34,080 --> 00:26:37,520 Speaker 1: pain information follows the same super highway and it goes 469 00:26:37,560 --> 00:26:40,800 Speaker 1: through your brain stem, your medula, and then it synapses 470 00:26:40,840 --> 00:26:44,600 Speaker 1: again onto a third set of neurons. Um in your thalamus, 471 00:26:44,600 --> 00:26:47,280 Speaker 1: which is your brain's relay center, and then from there 472 00:26:47,359 --> 00:26:49,239 Speaker 1: things start to get kind of market. It goes out 473 00:26:49,280 --> 00:26:51,920 Speaker 1: to different parts of the brain, and we'll talk about 474 00:26:51,960 --> 00:26:54,040 Speaker 1: pain in the brain in a second, but one thing 475 00:26:54,080 --> 00:26:56,400 Speaker 1: that it does it was helpful for me to imagine 476 00:26:56,880 --> 00:27:00,600 Speaker 1: pain a pain signal as like a pinball when when 477 00:27:00,680 --> 00:27:03,440 Speaker 1: you hit it with the flippers, say that's like you're 478 00:27:03,600 --> 00:27:06,680 Speaker 1: you cutting your hand. That pinball goes up and it's 479 00:27:06,720 --> 00:27:08,879 Speaker 1: going up to the top of the pinball machine. But 480 00:27:08,960 --> 00:27:10,880 Speaker 1: on the way, it goes through all these other things, 481 00:27:10,920 --> 00:27:13,200 Speaker 1: like these gates that it flips around three and sixty 482 00:27:13,240 --> 00:27:15,479 Speaker 1: degrees a bunch of time. Imagine that it's, you know, 483 00:27:15,560 --> 00:27:17,920 Speaker 1: doing that in your in your brain stem, or in 484 00:27:17,960 --> 00:27:20,000 Speaker 1: the gray matter of your spinal cord. It's going through 485 00:27:20,000 --> 00:27:21,960 Speaker 1: all these different things, and as it does on its 486 00:27:21,960 --> 00:27:26,000 Speaker 1: way to that final destination of the brain's somato sensory cortex, 487 00:27:26,560 --> 00:27:30,159 Speaker 1: it can have effects on the way to Like if 488 00:27:30,200 --> 00:27:33,360 Speaker 1: it's bad enough, it may enter what's called a spinal 489 00:27:33,440 --> 00:27:36,600 Speaker 1: reflex loop, where that pain signal doesn't even make it 490 00:27:36,640 --> 00:27:39,560 Speaker 1: to the brain before part of it gets redirected back 491 00:27:39,600 --> 00:27:42,360 Speaker 1: down to say, your hand to make your hand jerk 492 00:27:42,400 --> 00:27:45,400 Speaker 1: away from that hot stove before it even hit your brain. 493 00:27:45,760 --> 00:27:48,480 Speaker 1: Literally before your brain even knows that there's pain going on. 494 00:27:48,880 --> 00:27:51,000 Speaker 1: You're you have a signal going down to your arm 495 00:27:51,040 --> 00:27:53,919 Speaker 1: to say, move that move that hand, dummy. Yeah, because 496 00:27:54,040 --> 00:27:57,240 Speaker 1: if you think about burning your hand, the burn, I 497 00:27:57,280 --> 00:28:00,720 Speaker 1: mean it's very fast and very fast succession. The actual 498 00:28:01,040 --> 00:28:06,720 Speaker 1: burn pain burn happens after you've jerked your hand away. Uh. 499 00:28:06,760 --> 00:28:09,480 Speaker 1: And like I said, it's pretty lickety split, but you 500 00:28:09,560 --> 00:28:11,040 Speaker 1: jerk that hand away. It's not like you keep it 501 00:28:11,080 --> 00:28:13,040 Speaker 1: there and you're like, oh my goodness, I feel pain 502 00:28:13,119 --> 00:28:15,440 Speaker 1: on my hand. Oh my lord, it's got fire on it. 503 00:28:15,680 --> 00:28:18,920 Speaker 1: I should probably move it eventually. Another thing that can 504 00:28:18,960 --> 00:28:21,399 Speaker 1: happen is pain signals can set off your fight or 505 00:28:21,440 --> 00:28:25,080 Speaker 1: flight pathways as it's going through the medulla. It's been 506 00:28:25,119 --> 00:28:27,680 Speaker 1: a long time since we talked about or fight. Yeah, 507 00:28:27,680 --> 00:28:30,879 Speaker 1: it's it's been so long. They added a third one freeze. Ye. 508 00:28:32,119 --> 00:28:35,359 Speaker 1: It's like an old friend coming back to visit, but 509 00:28:35,440 --> 00:28:39,040 Speaker 1: bringing a new obnoxious friend with it. Yeah. So um, 510 00:28:39,080 --> 00:28:42,080 Speaker 1: it could set that off through the medulla. And you 511 00:28:42,080 --> 00:28:43,760 Speaker 1: know what happens there is you're gonna your heart rate 512 00:28:43,800 --> 00:28:45,840 Speaker 1: is gonna go up. Your blood pressure is gonna shoot up. 513 00:28:46,240 --> 00:28:50,520 Speaker 1: You're gonna start sweating if you're me rapid breathing, and 514 00:28:50,640 --> 00:28:54,880 Speaker 1: it really can. Um, it really depends on the intensity 515 00:28:54,920 --> 00:28:57,000 Speaker 1: of the pain, but it can definitely set off that 516 00:28:57,040 --> 00:29:00,200 Speaker 1: fight or flight or I guess freeze. And again, all 517 00:29:00,280 --> 00:29:02,880 Speaker 1: this is before it even gets to the brain. And 518 00:29:02,920 --> 00:29:04,800 Speaker 1: then finally when I, like I said, when it does 519 00:29:04,840 --> 00:29:07,320 Speaker 1: get to the brain, we're not quite sure what happens there. 520 00:29:07,360 --> 00:29:10,160 Speaker 1: We know from observations that the brain is definitely involved. 521 00:29:10,640 --> 00:29:12,680 Speaker 1: And um, one of the ways that we know this 522 00:29:12,760 --> 00:29:16,240 Speaker 1: is because, um, you will move your hands. Sometimes it's 523 00:29:16,240 --> 00:29:18,840 Speaker 1: not an immediate reaction, but sometimes it's a little later. 524 00:29:19,160 --> 00:29:21,479 Speaker 1: So clearly some of those signals get sent to the 525 00:29:21,520 --> 00:29:25,360 Speaker 1: motor cortex to say, Okay, get the hand out of there. Um. 526 00:29:25,400 --> 00:29:28,160 Speaker 1: But we also can tell from things like the fact 527 00:29:28,200 --> 00:29:31,760 Speaker 1: that if you consciously distract yourself from thinking about the 528 00:29:31,760 --> 00:29:35,000 Speaker 1: pain with something else, like do you remember how um, 529 00:29:35,160 --> 00:29:38,360 Speaker 1: Edward Norton in Fight Club when he had that lie 530 00:29:38,480 --> 00:29:41,400 Speaker 1: on his on the on his hand, he kept trying 531 00:29:41,400 --> 00:29:44,400 Speaker 1: to think of like a snow covered like forest or something. 532 00:29:44,680 --> 00:29:47,000 Speaker 1: He went to his his happy animal I think was 533 00:29:47,000 --> 00:29:49,280 Speaker 1: a penguin. That's right, that's right. He started to try 534 00:29:49,320 --> 00:29:52,640 Speaker 1: to concentrate on that and that it didn't work then, 535 00:29:52,760 --> 00:29:55,080 Speaker 1: but it could have worked depending on what other kind 536 00:29:55,120 --> 00:29:58,000 Speaker 1: of tissue damage was going on. And it really kind 537 00:29:58,000 --> 00:30:00,800 Speaker 1: of underscores the fact that if you think about something else, 538 00:30:01,320 --> 00:30:04,200 Speaker 1: your pain may decrease. Well, if the brain has nothing 539 00:30:04,240 --> 00:30:06,880 Speaker 1: to do with pain or controlling pain, then that wouldn't 540 00:30:06,920 --> 00:30:10,040 Speaker 1: happen at all. And so observations like that and some 541 00:30:10,120 --> 00:30:12,840 Speaker 1: other ones show us that, Okay, the brain is definitely 542 00:30:12,920 --> 00:30:15,880 Speaker 1: involved in this in some way, shape or form, and 543 00:30:16,240 --> 00:30:20,360 Speaker 1: pain is not just the reception of um a pain 544 00:30:20,400 --> 00:30:23,080 Speaker 1: signal coming from the lower parts of the body up 545 00:30:23,120 --> 00:30:25,640 Speaker 1: to the brain. But there's also a reciprocal thing, like 546 00:30:25,680 --> 00:30:29,240 Speaker 1: you were saying, where the brain descends um or, there's 547 00:30:29,280 --> 00:30:31,800 Speaker 1: descending pathways that the brain uses to say, Okay, alright, 548 00:30:32,040 --> 00:30:34,320 Speaker 1: let's just all chill out down there, Okay, let me 549 00:30:34,360 --> 00:30:36,520 Speaker 1: figure this out. Everybody, just shut up, shut up. I 550 00:30:36,560 --> 00:30:39,640 Speaker 1: can't think when you're all screaming at me. Yeah. And 551 00:30:40,360 --> 00:30:43,120 Speaker 1: as those signals are on the way down, there might 552 00:30:43,160 --> 00:30:46,959 Speaker 1: be those uh, ascending nerve signals going up right, and 553 00:30:47,000 --> 00:30:50,240 Speaker 1: those descending signals could overpower and say hold on, you 554 00:30:50,280 --> 00:30:53,640 Speaker 1: stop right there, buddy, I'm trying to calm this person down. 555 00:30:54,160 --> 00:30:57,960 Speaker 1: You just you just stay put, right, And so there's um, 556 00:30:58,000 --> 00:31:00,800 Speaker 1: there's other things that that we figured out that can 557 00:31:00,840 --> 00:31:06,440 Speaker 1: actually influence your experience of pain. Like to say that 558 00:31:06,480 --> 00:31:10,240 Speaker 1: it's subjective is just no joke. There's probably no experience 559 00:31:10,720 --> 00:31:14,080 Speaker 1: more subjective than the experience of pain. And there's all 560 00:31:14,120 --> 00:31:17,520 Speaker 1: these different factors that are involved that will have an 561 00:31:17,560 --> 00:31:21,520 Speaker 1: impact on how much or how little pain you experience. 562 00:31:21,600 --> 00:31:25,520 Speaker 1: You know. I think improv comedy is the first that's right, 563 00:31:26,120 --> 00:31:30,640 Speaker 1: man to see good improv is just it's just so rare, 564 00:31:30,720 --> 00:31:33,560 Speaker 1: but it's so good when it is good. Yeah, I mean, 565 00:31:33,600 --> 00:31:36,000 Speaker 1: I've seen a handful in my life that just blew 566 00:31:36,080 --> 00:31:39,360 Speaker 1: me away, and I've seen a bunch more that. Uh, 567 00:31:39,480 --> 00:31:42,360 Speaker 1: it's tough to get through. It's like horror movies, Like 568 00:31:42,400 --> 00:31:45,080 Speaker 1: a truly great horror movie is really tough to beat. 569 00:31:45,680 --> 00:31:50,120 Speaker 1: But there's a lot of really bad horror movies out there. Yeah, 570 00:31:50,160 --> 00:31:53,560 Speaker 1: a lot of good ones these days, Thoughnas what you 571 00:31:53,640 --> 00:31:56,920 Speaker 1: got well, I mean in the past five or six years, 572 00:31:56,960 --> 00:32:04,920 Speaker 1: I think, uh, it follows and the and Hereditary, and 573 00:32:04,960 --> 00:32:08,920 Speaker 1: I think there's been a bunch of new horror masters 574 00:32:08,960 --> 00:32:10,760 Speaker 1: So now, this was not a horror movie, but I 575 00:32:10,800 --> 00:32:15,240 Speaker 1: want to shout out Um and Nola Holmes on Netflix. 576 00:32:15,320 --> 00:32:19,120 Speaker 1: Have you seen it? It's a coming of age movie 577 00:32:19,600 --> 00:32:25,560 Speaker 1: about Sherlock Holmes's younger sister. Interesting and it's super cute, 578 00:32:25,560 --> 00:32:29,760 Speaker 1: but it's also really smart, like very smart, and it 579 00:32:29,800 --> 00:32:32,320 Speaker 1: takes the takes it for granted that the viewers smart 580 00:32:32,320 --> 00:32:35,840 Speaker 1: and paying attention. It's a really great, great movie, great movie. 581 00:32:35,840 --> 00:32:38,360 Speaker 1: You have to check that out. It's um Millie Bobby 582 00:32:38,400 --> 00:32:42,520 Speaker 1: Brown as Nola Homes just about She's about as charming 583 00:32:42,560 --> 00:32:46,560 Speaker 1: as they come. She's wonderful. So yeah, not a horror movie, 584 00:32:46,560 --> 00:32:49,120 Speaker 1: but definitely worth watching regardless. Is that based on any 585 00:32:49,320 --> 00:32:52,960 Speaker 1: uh literature or anything or did they just say, like, hey, 586 00:32:53,160 --> 00:32:55,720 Speaker 1: what if he had a little sister. I hadn't thought 587 00:32:55,720 --> 00:32:58,200 Speaker 1: about it, but I think it's the ladder of the two, 588 00:32:58,240 --> 00:33:02,320 Speaker 1: which makes it all the more amazing because they did 589 00:33:02,400 --> 00:33:06,120 Speaker 1: such a great job of capturing that whole um, that 590 00:33:06,200 --> 00:33:11,360 Speaker 1: whole world. Very cool. Yeah, where should we take a break? Yeah? 591 00:33:11,400 --> 00:33:13,280 Speaker 1: Why not? Let's let's take a break and we'll come 592 00:33:13,320 --> 00:33:14,880 Speaker 1: back and talk about a few of the factors that 593 00:33:14,960 --> 00:33:44,040 Speaker 1: influence your experience of pain. So, um, we're saying before 594 00:33:44,040 --> 00:33:47,040 Speaker 1: we started talking about in Nola Holmes and horror movies, 595 00:33:47,480 --> 00:33:49,520 Speaker 1: that there's like a lot of different things that will 596 00:33:49,560 --> 00:33:53,640 Speaker 1: influence an individual's experience of pain. Um. And it has 597 00:33:53,720 --> 00:33:58,160 Speaker 1: to do with not just you biologically, but weirdly also 598 00:33:58,320 --> 00:34:02,840 Speaker 1: you sociologic le too. Yeah, and this first one um 599 00:34:02,960 --> 00:34:08,720 Speaker 1: age is to me a little counterintuitive. Um. In some ways, 600 00:34:08,840 --> 00:34:11,000 Speaker 1: your you know, as you age, your brain circuitry is 601 00:34:11,000 --> 00:34:14,759 Speaker 1: gonna it's just gonna degenerate a little bit. That's just 602 00:34:15,719 --> 00:34:19,359 Speaker 1: that's sad fact of the matter. And if you are 603 00:34:20,480 --> 00:34:23,520 Speaker 1: one of our seniors, and if you're a senior that's listening. Hello, 604 00:34:24,120 --> 00:34:26,799 Speaker 1: got an email from a lovely eight year old lady 605 00:34:26,800 --> 00:34:28,879 Speaker 1: the other day that just warmed my heart. Oh yes, 606 00:34:28,960 --> 00:34:31,480 Speaker 1: she was great. She was great. So, um, if you 607 00:34:31,520 --> 00:34:34,480 Speaker 1: are one of our senior listeners and you, um, you 608 00:34:34,560 --> 00:34:37,479 Speaker 1: might have a lower pain threshold and more problems dealing 609 00:34:37,560 --> 00:34:41,000 Speaker 1: with pain. Um. This seemed a little counterintuitive because I 610 00:34:41,000 --> 00:34:45,279 Speaker 1: could also see a case where, uh, the neurons don't 611 00:34:45,320 --> 00:34:48,080 Speaker 1: fire in the correct way, such that you could be 612 00:34:48,160 --> 00:34:51,000 Speaker 1: feeling something painful and not really realize it. So the 613 00:34:51,040 --> 00:34:52,920 Speaker 1: way I took it was a little different that it 614 00:34:53,000 --> 00:34:55,520 Speaker 1: was almost like you know how when you form a 615 00:34:55,560 --> 00:34:58,360 Speaker 1: habit or a memory or something, it's because the neural 616 00:34:58,360 --> 00:35:01,040 Speaker 1: connection has gone over again and again. So like that 617 00:35:01,080 --> 00:35:04,719 Speaker 1: pathways is kind of blazed a little more clearly. My 618 00:35:04,840 --> 00:35:07,920 Speaker 1: interpretation was that the same can be true with pain, 619 00:35:08,320 --> 00:35:10,440 Speaker 1: to where once you fire a few times are over 620 00:35:10,480 --> 00:35:13,800 Speaker 1: and over again, it becomes easier to conduct that pain 621 00:35:13,920 --> 00:35:18,640 Speaker 1: signal more efficiently, and so that would account for sensitization. 622 00:35:18,719 --> 00:35:21,680 Speaker 1: That's how I took it. You know, hey, I'm no 623 00:35:21,800 --> 00:35:26,640 Speaker 1: vs rama sham drawn. Uh. There's also gender, and because 624 00:35:26,680 --> 00:35:31,000 Speaker 1: we're talking about medical research, they are basically still saying 625 00:35:31,120 --> 00:35:33,160 Speaker 1: men and women, and they're not doing research along the 626 00:35:33,200 --> 00:35:37,360 Speaker 1: gender spectrum. So having said that, research shows that women 627 00:35:37,400 --> 00:35:41,120 Speaker 1: have a higher sensitivity to pain than men. Uh, could 628 00:35:41,120 --> 00:35:45,680 Speaker 1: be maybe physic psychosocial stuff at work, because you know, 629 00:35:45,719 --> 00:35:48,359 Speaker 1: men are supposed to not show their pain or not 630 00:35:48,400 --> 00:35:51,440 Speaker 1: report pain or just suck it up. Dude. Uh, there 631 00:35:51,440 --> 00:35:53,320 Speaker 1: could be that at work. It also could be sex 632 00:35:53,360 --> 00:35:57,960 Speaker 1: linked genetic traits or hormonal changes that might change that 633 00:35:58,040 --> 00:36:01,160 Speaker 1: pain perception, right, or even the culture you're raised in, 634 00:36:01,239 --> 00:36:04,920 Speaker 1: like um women in Uganda, I read are expected to 635 00:36:05,040 --> 00:36:08,080 Speaker 1: be stoic in the face of pain. Um, whereas men 636 00:36:08,120 --> 00:36:12,040 Speaker 1: in Ukraine are expected to not h experience pain at 637 00:36:12,040 --> 00:36:15,120 Speaker 1: all or show any kind of pain whatsoever. Um. So 638 00:36:15,239 --> 00:36:18,319 Speaker 1: like the idea that culture can affect your interpretation or 639 00:36:18,320 --> 00:36:20,200 Speaker 1: how you experience pain is kind of weird if you 640 00:36:20,200 --> 00:36:22,919 Speaker 1: think about it. It's also weird because I know many 641 00:36:22,960 --> 00:36:25,680 Speaker 1: many women who would say, are you kidding me? My 642 00:36:25,760 --> 00:36:29,160 Speaker 1: husband is the biggest whiny baby every time he gets sick. Uh, 643 00:36:29,200 --> 00:36:31,400 Speaker 1: And I generally suck it up as the wife, So 644 00:36:31,560 --> 00:36:34,799 Speaker 1: you gandon and so you gandon. There's also memory, like 645 00:36:35,200 --> 00:36:38,279 Speaker 1: if you've experienced pain before, your memory of going through 646 00:36:38,320 --> 00:36:41,560 Speaker 1: that pain can impact how you experience it a follow 647 00:36:41,640 --> 00:36:45,840 Speaker 1: up time too. Yeah, and for both ways. Like I 648 00:36:45,920 --> 00:36:48,080 Speaker 1: used to be really, really really scared of needles, and 649 00:36:48,120 --> 00:36:50,839 Speaker 1: I think that was because I went a long time 650 00:36:50,880 --> 00:36:55,239 Speaker 1: without getting shots. Um. I think when you know, when 651 00:36:55,280 --> 00:36:57,160 Speaker 1: I was younger and in college, like I wasn't giving 652 00:36:57,160 --> 00:37:00,000 Speaker 1: blood like I should, and I wasn't getting flu shot 653 00:37:00,000 --> 00:37:02,319 Speaker 1: it's like I should. But now that I'm a real 654 00:37:02,520 --> 00:37:05,200 Speaker 1: sentient adult and responsible adult, I have needles in me 655 00:37:05,239 --> 00:37:08,759 Speaker 1: all the time, and it's I'm not They don't really 656 00:37:08,840 --> 00:37:11,120 Speaker 1: hurt that bad anymore. So when I go back I 657 00:37:11,160 --> 00:37:13,200 Speaker 1: get that initial fear of the needle because I've always 658 00:37:13,200 --> 00:37:15,560 Speaker 1: had it, But then my brain tells me, hey, Chuck, 659 00:37:15,600 --> 00:37:17,959 Speaker 1: it's not that bad, remember do you just just suck 660 00:37:18,000 --> 00:37:21,120 Speaker 1: it up and get the shot. My my sister in 661 00:37:21,200 --> 00:37:26,399 Speaker 1: law is like a genuine shout no and run out 662 00:37:26,440 --> 00:37:31,320 Speaker 1: of the room, like, yeah, needle Phobe, that's a great 663 00:37:31,520 --> 00:37:35,200 Speaker 1: band name. Oh my god, that's the best band name 664 00:37:35,280 --> 00:37:38,960 Speaker 1: in years, Chuck. What kind of band is that? Uh? 665 00:37:39,160 --> 00:37:44,759 Speaker 1: Needle Phobe is clearly some sort of metal, maybe new 666 00:37:44,760 --> 00:37:47,640 Speaker 1: metal if it were going to be ruined. But there's 667 00:37:47,640 --> 00:37:49,400 Speaker 1: definitely something, and there may be along the lines of 668 00:37:49,400 --> 00:37:51,799 Speaker 1: like Queens Rich or something. Yeah, I could see that, 669 00:37:51,920 --> 00:37:57,040 Speaker 1: or maybe even like horror metal. Oh yeah, like that 670 00:37:57,120 --> 00:38:02,080 Speaker 1: Norwegian stuff. Sure, Okay, so it's about to get weirder, Chuck. 671 00:38:02,160 --> 00:38:05,960 Speaker 1: So you're talking about needles. If you look at a 672 00:38:06,040 --> 00:38:09,239 Speaker 1: needle injected into your arm, it hurts more than if 673 00:38:09,239 --> 00:38:11,600 Speaker 1: you're not looking. Even if you're thinking about the needle 674 00:38:11,640 --> 00:38:15,200 Speaker 1: injecting into your arm being injected in your arm, just 675 00:38:15,719 --> 00:38:18,800 Speaker 1: not looking at it makes it hurt less, studies have shown, 676 00:38:18,840 --> 00:38:21,680 Speaker 1: which is weird, but in a sense it also makes 677 00:38:21,719 --> 00:38:25,680 Speaker 1: sense because you're being provided with additional information about that 678 00:38:26,080 --> 00:38:29,399 Speaker 1: through your eyes, so your brain has more information than 679 00:38:29,440 --> 00:38:33,280 Speaker 1: it otherwise would have, which can actually make it hurt more. Yeah, 680 00:38:33,280 --> 00:38:36,040 Speaker 1: and I know I've mentioned this, I still gotta look. Um. 681 00:38:36,080 --> 00:38:38,640 Speaker 1: I used to request a mirror to look at dental 682 00:38:38,640 --> 00:38:42,080 Speaker 1: work as it was going on. I don't do that anymore. 683 00:38:42,120 --> 00:38:44,000 Speaker 1: I try and just check out, but I always have 684 00:38:44,040 --> 00:38:46,200 Speaker 1: to look at the needle. There's no way. Yeah. Same here, 685 00:38:46,239 --> 00:38:50,640 Speaker 1: I'm like, do it slower. You're not a needle fobe, 686 00:38:50,640 --> 00:38:53,640 Speaker 1: You're a needle uh whatever. The opposite is file a 687 00:38:53,640 --> 00:38:57,360 Speaker 1: needle file. Um. So. And then there's emotions too, and 688 00:38:57,440 --> 00:38:59,880 Speaker 1: not just you know, like you were saying earlier, there's something. 689 00:39:00,040 --> 00:39:03,719 Speaker 1: There's a different thing psychic pain. Where you are your 690 00:39:03,719 --> 00:39:09,000 Speaker 1: emotions are so overwrought that you actually feel physically uncomfortable 691 00:39:09,160 --> 00:39:13,480 Speaker 1: or hurt from it. That's different. Your emotions can actually 692 00:39:13,520 --> 00:39:18,120 Speaker 1: affect physical pain as well. Yeah, and back when we 693 00:39:18,120 --> 00:39:20,839 Speaker 1: were trying to understand and we're still trying to understand this, 694 00:39:20,960 --> 00:39:25,400 Speaker 1: but um, why emotions and stuff might influence pain. In 695 00:39:25,440 --> 00:39:27,719 Speaker 1: the sixties, of course, when all this kind of cool 696 00:39:27,719 --> 00:39:30,360 Speaker 1: research was going on, there were a couple of dudes 697 00:39:30,440 --> 00:39:35,040 Speaker 1: named Ronald mel Zack and Patrick Wall, who threw up 698 00:39:35,200 --> 00:39:39,880 Speaker 1: a proposal about a gating mechanism existing among the connections 699 00:39:39,880 --> 00:39:43,520 Speaker 1: in the body sensory pathways that can help determine how 700 00:39:43,560 --> 00:39:48,000 Speaker 1: you're gonna feel pain and how that works with the brain. Yeah, 701 00:39:48,040 --> 00:39:51,319 Speaker 1: because so there's the ascending painful pathways and then the 702 00:39:51,360 --> 00:39:55,319 Speaker 1: descending let's all just mellow out pathways. And I don't 703 00:39:55,360 --> 00:39:58,520 Speaker 1: know if we knew that before um Melzack and Wall, 704 00:39:58,760 --> 00:40:00,520 Speaker 1: or if we know it as a result to them, 705 00:40:00,560 --> 00:40:04,400 Speaker 1: But the current general understanding of pain is this gate 706 00:40:04,440 --> 00:40:10,640 Speaker 1: control theory, where this there's stimulation of these pathways going 707 00:40:10,800 --> 00:40:13,239 Speaker 1: up to the brain and they have to be of 708 00:40:13,280 --> 00:40:19,080 Speaker 1: like a certain amount to overcome an inhibitory neuron. And 709 00:40:19,120 --> 00:40:21,880 Speaker 1: so if you I just like press you know, my arm, 710 00:40:21,920 --> 00:40:26,839 Speaker 1: I'm sending somato sensory information through those same pain pathways, 711 00:40:27,239 --> 00:40:31,240 Speaker 1: but that the inhibitory neuron that keeps those the pain 712 00:40:31,280 --> 00:40:36,719 Speaker 1: projector neurons from firing, are not overcome. But if I, 713 00:40:36,719 --> 00:40:40,160 Speaker 1: if I, you know, took a butcher knife and cut 714 00:40:40,200 --> 00:40:43,040 Speaker 1: that same part of my arm, they would be overcome. 715 00:40:43,120 --> 00:40:45,799 Speaker 1: The inhibitory neuron would basically be turned off by the 716 00:40:45,840 --> 00:40:48,880 Speaker 1: signal the intensity of the signal, and that projector neuron 717 00:40:48,920 --> 00:40:52,600 Speaker 1: would fire, and now our brains would have that pain signal, saying, 718 00:40:54,719 --> 00:40:57,560 Speaker 1: in that case, the gate is fully open for business. 719 00:40:58,120 --> 00:41:02,160 Speaker 1: And when otherwise, when there's no pain, no no sensory information, 720 00:41:02,200 --> 00:41:06,440 Speaker 1: the gates closed, or if it's just normal somatosensory information, 721 00:41:06,480 --> 00:41:09,200 Speaker 1: the gates still closed. It's just when it's that that 722 00:41:09,360 --> 00:41:12,879 Speaker 1: intensity of the pain information that the gate flies open. Yeah, 723 00:41:12,880 --> 00:41:16,560 Speaker 1: and this is interesting because it doesn't explain everything, but 724 00:41:16,719 --> 00:41:20,040 Speaker 1: it does explain like when you um, like if you 725 00:41:20,040 --> 00:41:22,960 Speaker 1: smash your thumb with a hammer, and your reaction is 726 00:41:23,000 --> 00:41:26,480 Speaker 1: to go and shake your hand really hard or too 727 00:41:26,600 --> 00:41:28,640 Speaker 1: or to suck on it. Maybe if you smash your 728 00:41:28,640 --> 00:41:30,120 Speaker 1: finger with a hammer. It seems like a weird thing 729 00:41:30,160 --> 00:41:32,839 Speaker 1: to do. I know it is, but it works. It does. 730 00:41:32,920 --> 00:41:37,560 Speaker 1: That stimulates your normal somatosensory input to those projector neurons, 731 00:41:37,600 --> 00:41:40,960 Speaker 1: and that's going to help override the projection neurons that 732 00:41:41,239 --> 00:41:45,040 Speaker 1: uh and you know, basically kind of close that gate down. Okay, 733 00:41:45,280 --> 00:41:47,480 Speaker 1: So now that you understand the gate theory of pain, 734 00:41:47,520 --> 00:41:51,920 Speaker 1: and this is the general understanding among Western science medicine 735 00:41:51,960 --> 00:41:55,000 Speaker 1: of pain. This is pretty much the common knowledge. Now 736 00:41:55,400 --> 00:41:58,120 Speaker 1: you can understand how it can go wrong, and so 737 00:41:58,239 --> 00:42:01,880 Speaker 1: they think that this also explain how the how you 738 00:42:01,880 --> 00:42:05,960 Speaker 1: can experience psychogenic pain where people have fibro mayalgia or 739 00:42:06,040 --> 00:42:10,600 Speaker 1: chronic pelvic pain, or tenitis or t mj or um 740 00:42:10,680 --> 00:42:14,480 Speaker 1: chronic back pain when there's no reason whatsoever for them 741 00:42:14,520 --> 00:42:18,520 Speaker 1: to experience this. The Um the really great author in 742 00:42:18,640 --> 00:42:21,440 Speaker 1: Surgeon a Tool go on Day, I believe he rights 743 00:42:21,480 --> 00:42:23,799 Speaker 1: for The New Yorker. He's also he writes some books 744 00:42:23,840 --> 00:42:26,200 Speaker 1: as well. He's one of one of the best writers 745 00:42:26,239 --> 00:42:28,920 Speaker 1: out there right now, and he's also a very accomplished surgeon. 746 00:42:29,360 --> 00:42:33,920 Speaker 1: And he he likens that situation to a faulty car sensor, 747 00:42:34,040 --> 00:42:36,880 Speaker 1: where if you have a sensor on your dashboard coming 748 00:42:36,880 --> 00:42:39,200 Speaker 1: on saying like, hey you got an engine problem, and 749 00:42:39,200 --> 00:42:40,759 Speaker 1: you go to the mechanic and the mechanics like you 750 00:42:40,760 --> 00:42:43,760 Speaker 1: don't have an engine problem. Eventually they're going to figure 751 00:42:43,760 --> 00:42:46,640 Speaker 1: out that the problems with the sensor itself, and they 752 00:42:46,680 --> 00:42:49,840 Speaker 1: think that this is because of this gate being opened. 753 00:42:49,880 --> 00:42:54,719 Speaker 1: The sensor um is open, even though there's nothing tripping it. Um, 754 00:42:54,760 --> 00:42:57,000 Speaker 1: that that is the problem, that that is what it 755 00:42:57,080 --> 00:43:02,200 Speaker 1: counts for psychogenic pain. Very interesting and it's gonna make sense, Yeah, definitely. 756 00:43:02,840 --> 00:43:06,320 Speaker 1: So when it comes to managing pain. Uh, there are 757 00:43:06,520 --> 00:43:09,400 Speaker 1: a bunch of different routes you can go, UM, depending 758 00:43:09,520 --> 00:43:12,239 Speaker 1: on what your doctor might recommend, depending on what you 759 00:43:12,320 --> 00:43:15,200 Speaker 1: as a human, UM, what what road you want to 760 00:43:15,239 --> 00:43:18,560 Speaker 1: go down? Uh, and these very uh and we'll you know, 761 00:43:18,600 --> 00:43:21,040 Speaker 1: we'll get into these, but these very from like over 762 00:43:21,080 --> 00:43:27,480 Speaker 1: the counter medications to prescription medications to surgery, to go 763 00:43:27,520 --> 00:43:33,200 Speaker 1: into a massage therapist or a uh an acupuncture specialist, acupuncturist. 764 00:43:33,760 --> 00:43:35,759 Speaker 1: But as far as the medications go, you've got a 765 00:43:35,800 --> 00:43:39,799 Speaker 1: couple of different kinds. UM. You've got your non opioid 766 00:43:39,880 --> 00:43:42,840 Speaker 1: analgesic like this is a tail in all or in 767 00:43:42,880 --> 00:43:45,800 Speaker 1: a lever or an advil or something like that, and 768 00:43:46,200 --> 00:43:48,319 Speaker 1: it's going to act at the side of the pain. UM. 769 00:43:48,360 --> 00:43:51,680 Speaker 1: When you have that damaged tissue, it releases enzymes that 770 00:43:51,800 --> 00:43:55,520 Speaker 1: stimulate the pain receptors locally. And what these do is 771 00:43:55,560 --> 00:43:58,400 Speaker 1: they interfere with those enzymes are going to reduce inflammation 772 00:43:59,120 --> 00:44:02,680 Speaker 1: and hopefully reduce pain. Yeah, which is really interesting because 773 00:44:02,680 --> 00:44:06,560 Speaker 1: that is your mind saying this pain is not nothing 774 00:44:06,600 --> 00:44:08,680 Speaker 1: that my brain needs to worry about. I'm going to 775 00:44:08,719 --> 00:44:12,560 Speaker 1: actually go to the site and cancel out those those 776 00:44:12,600 --> 00:44:16,479 Speaker 1: pain signals where they're beginning, because I'm judging that they're 777 00:44:16,520 --> 00:44:19,520 Speaker 1: not that important. Pretty cool, Yeah, it is cool, but 778 00:44:19,560 --> 00:44:22,239 Speaker 1: these can have effects on the liver and kidneys if 779 00:44:22,239 --> 00:44:24,440 Speaker 1: you use them a lot. So you know, you don't 780 00:44:24,440 --> 00:44:27,240 Speaker 1: want to, uh, you don't want to pop an advil 781 00:44:27,280 --> 00:44:29,319 Speaker 1: every day if you have like back pain, that kind 782 00:44:29,320 --> 00:44:34,080 Speaker 1: of thing. Um. And then there's opioids which, um they 783 00:44:34,120 --> 00:44:38,360 Speaker 1: actually go to the gate um and they can close 784 00:44:38,440 --> 00:44:40,839 Speaker 1: the gate on the one hand, and then they can 785 00:44:40,840 --> 00:44:44,879 Speaker 1: also go to your brain and um excite in the 786 00:44:44,920 --> 00:44:49,400 Speaker 1: descending pathways which will bind with like opioid receptors. And 787 00:44:49,440 --> 00:44:53,840 Speaker 1: of course those are hugely addictive and have a huge 788 00:44:54,120 --> 00:44:59,040 Speaker 1: um possibility of of overdose as well, but they do 789 00:44:59,320 --> 00:45:02,680 Speaker 1: help treat pain a lot. Yeah, we should do one 790 00:45:02,680 --> 00:45:06,520 Speaker 1: of opioids and the opioid epidemic. It's I agree. It's 791 00:45:06,520 --> 00:45:10,520 Speaker 1: been one of the darker spots of the new era. Yes, 792 00:45:10,680 --> 00:45:15,480 Speaker 1: the new era, I don't even know the last ten 793 00:45:15,560 --> 00:45:17,839 Speaker 1: or fifteen years. That's what I call that. A new era. 794 00:45:17,920 --> 00:45:20,960 Speaker 1: The modern era is what I meant. Uh, what else 795 00:45:21,000 --> 00:45:25,280 Speaker 1: do we have there? Um, you can actually use medicines 796 00:45:25,320 --> 00:45:27,880 Speaker 1: that aren't meant for treating pain to treat pain, like 797 00:45:28,040 --> 00:45:32,920 Speaker 1: anti epileptic drugs, brand stuff, antidepressants, anesthetics. They all do 798 00:45:33,000 --> 00:45:36,080 Speaker 1: things like they block can like nerve conduction in some 799 00:45:36,160 --> 00:45:39,160 Speaker 1: specific area, and so they weren't Yeah, they weren't meant 800 00:45:39,200 --> 00:45:42,160 Speaker 1: to be treated for or used for pain, but they 801 00:45:42,200 --> 00:45:44,560 Speaker 1: actually can come in handy for things like chronic pain 802 00:45:44,640 --> 00:45:47,960 Speaker 1: or neuropathic pain. Yeah. You can also have surgery is 803 00:45:48,000 --> 00:45:51,000 Speaker 1: a kind of a last resort um if you have 804 00:45:52,040 --> 00:45:53,759 Speaker 1: severe I've not had a couple of friends, actually you 805 00:45:53,800 --> 00:45:55,560 Speaker 1: have had back surgery where let's say you have a 806 00:45:55,600 --> 00:45:59,280 Speaker 1: herniated disk and that thing is compressing on a nerve. 807 00:46:00,080 --> 00:46:02,280 Speaker 1: As a last resort, they can go in there and 808 00:46:03,160 --> 00:46:05,359 Speaker 1: maybe remove a little bit of that disk that's hitting 809 00:46:05,400 --> 00:46:08,680 Speaker 1: that nerve and relieve that pressure. Yeah, and from what 810 00:46:08,719 --> 00:46:10,840 Speaker 1: I've seen, yes, that is meant to be a last resort. 811 00:46:10,920 --> 00:46:13,000 Speaker 1: There's also like cord ectomies where they go in and 812 00:46:13,040 --> 00:46:15,600 Speaker 1: say we're just gonna snip that gate so that it 813 00:46:15,680 --> 00:46:18,480 Speaker 1: just doesn't function at all anymore and make you a 814 00:46:18,480 --> 00:46:22,760 Speaker 1: super soldier. And then there's also alternative therapies and mental 815 00:46:22,800 --> 00:46:26,480 Speaker 1: control techniques and these work of varying degrees um. One 816 00:46:26,520 --> 00:46:30,560 Speaker 1: of my favorite alternative therapies. Is the TENS unit transcutaneous 817 00:46:30,600 --> 00:46:35,640 Speaker 1: electrical nerve stimulation and it sends electrical impulses from the 818 00:46:35,719 --> 00:46:40,000 Speaker 1: site of pain to base. It's basically like a defibrillator 819 00:46:40,120 --> 00:46:43,120 Speaker 1: for your pain gate. It's saying your pain gate is 820 00:46:43,120 --> 00:46:45,480 Speaker 1: is it's open, and it shouldn't be open. So we're 821 00:46:45,520 --> 00:46:48,000 Speaker 1: gonna We're gonna send some nerve stimulation and the hopes 822 00:46:48,040 --> 00:46:51,400 Speaker 1: that we can restart that inhibitory neuron and get it 823 00:46:51,440 --> 00:46:55,520 Speaker 1: closing that pain gate, or and or we can make 824 00:46:55,560 --> 00:46:57,399 Speaker 1: it all the way up to the brain and get 825 00:46:57,440 --> 00:47:01,279 Speaker 1: the brains descending pathways kick started as well. Is that 826 00:47:01,320 --> 00:47:04,280 Speaker 1: like when uh, like I had a back thing about 827 00:47:04,320 --> 00:47:07,360 Speaker 1: five years ago where they gave me this electro stimulator 828 00:47:07,400 --> 00:47:09,480 Speaker 1: thing that I put these little pads on the and 829 00:47:09,480 --> 00:47:11,400 Speaker 1: there's like a little handheld thing about the size of 830 00:47:11,400 --> 00:47:14,359 Speaker 1: a game boy that was connected to uh, not mine, 831 00:47:14,400 --> 00:47:16,319 Speaker 1: but I'm sure they're all different kinds. But you could 832 00:47:16,400 --> 00:47:19,720 Speaker 1: basically level the amount of sort of low level shock 833 00:47:20,360 --> 00:47:22,440 Speaker 1: and uh when you turn that thing all the way up, man, 834 00:47:22,480 --> 00:47:25,359 Speaker 1: it was it was pretty intense. Yeah, that's a TENS unit, 835 00:47:25,640 --> 00:47:27,279 Speaker 1: And as a matter of fact, that's based on some 836 00:47:27,440 --> 00:47:31,600 Speaker 1: really ancient thinking Apparently the pre Dynastic Egyptians from like 837 00:47:31,680 --> 00:47:35,040 Speaker 1: five thousand years ago used electric catfish from the Nile 838 00:47:35,200 --> 00:47:40,239 Speaker 1: for the same effect and impact. It's pretty amazing. Yeah. Uh. 839 00:47:40,280 --> 00:47:42,359 Speaker 1: And then you know we mentioned going to the chiropractor, 840 00:47:42,360 --> 00:47:47,000 Speaker 1: massage therapist. Um. Obviously they're hot compresses and cold compresses. 841 00:47:47,000 --> 00:47:53,040 Speaker 1: There's acupuncture, Um, there is you know, relaxation and hypnosis. 842 00:47:53,680 --> 00:47:56,719 Speaker 1: And we've already talked about distraction. If you want to 843 00:47:56,760 --> 00:47:58,439 Speaker 1: know what you think about hypnosis, we did a pretty 844 00:47:58,440 --> 00:48:02,120 Speaker 1: good episode on it a while back. Um. So, yeah, 845 00:48:02,120 --> 00:48:05,360 Speaker 1: they are all sorts of mental ways because they've shown 846 00:48:05,440 --> 00:48:09,799 Speaker 1: that that oh I'm blanking out what do you call 847 00:48:09,840 --> 00:48:15,359 Speaker 1: the drugs that aren't real drugs? What are the sugar bills? Placebos? Yeah, 848 00:48:15,400 --> 00:48:17,759 Speaker 1: that that placebos have been shown to work sometimes with 849 00:48:18,080 --> 00:48:21,200 Speaker 1: with limiting pain. Yeah yeah, And I mean you can 850 00:48:21,200 --> 00:48:23,759 Speaker 1: trick the brain for sure into not feeling pain. Like 851 00:48:23,800 --> 00:48:27,560 Speaker 1: Phantom limb treatment usually or sometimes involves a mirror where 852 00:48:27,560 --> 00:48:30,640 Speaker 1: you put a mirror over the amputated limb that's experienced pain, 853 00:48:31,120 --> 00:48:33,600 Speaker 1: and you move the other limb while you're looking in 854 00:48:33,600 --> 00:48:35,640 Speaker 1: the mirror, so it looks like you're amputated limb is 855 00:48:35,680 --> 00:48:38,080 Speaker 1: back and you're tricking your brain into being like, Okay, 856 00:48:38,160 --> 00:48:40,920 Speaker 1: it's there, it's fine, I don't have to experience pain anymore. 857 00:48:40,920 --> 00:48:43,960 Speaker 1: And it actually works. Yeah, but there's there's a you know, 858 00:48:44,239 --> 00:48:47,120 Speaker 1: there's a threshold there, like you can mind over matter 859 00:48:47,160 --> 00:48:50,960 Speaker 1: it to a certain degree. But um, as you say 860 00:48:51,000 --> 00:48:53,960 Speaker 1: in the article, like your mind and your brain are 861 00:48:53,960 --> 00:48:57,400 Speaker 1: two different things, so like you can't shut down that 862 00:48:57,440 --> 00:49:00,480 Speaker 1: gateway just by thinking it away. No, And there's a 863 00:49:00,520 --> 00:49:03,560 Speaker 1: real like push to to believe that over the last 864 00:49:03,560 --> 00:49:06,120 Speaker 1: few decades. But it's just it's becoming clear you can 865 00:49:06,200 --> 00:49:08,640 Speaker 1: impact it to some degree, but just not to to 866 00:49:08,880 --> 00:49:11,160 Speaker 1: a full degree. Yeah, And I think the mind over 867 00:49:11,200 --> 00:49:15,160 Speaker 1: matter is a person like the pain doesn't go away. 868 00:49:15,840 --> 00:49:18,480 Speaker 1: You're just able to mentally overcome it such that you're 869 00:49:18,520 --> 00:49:20,960 Speaker 1: not gonna either show it or let it get to 870 00:49:21,000 --> 00:49:23,640 Speaker 1: you or let it affect you. Right, you have actually 871 00:49:23,719 --> 00:49:26,560 Speaker 1: a lower stress response, and at the same time it 872 00:49:26,600 --> 00:49:29,040 Speaker 1: also cuts down on suffering, which is different from the 873 00:49:29,040 --> 00:49:32,600 Speaker 1: experience of pain. It's like associated with pain, and that's 874 00:49:32,640 --> 00:49:35,640 Speaker 1: like like that whole y Me thing and that seems 875 00:49:35,680 --> 00:49:40,000 Speaker 1: to be fixated on anticipating more pain in the immediate future. 876 00:49:40,360 --> 00:49:43,719 Speaker 1: And people who are mindful and meditate can actually cut 877 00:49:43,760 --> 00:49:46,600 Speaker 1: down and alleviate that suffering. So they experience pain, but 878 00:49:46,640 --> 00:49:48,640 Speaker 1: it goes away a lot faster in their response to 879 00:49:48,680 --> 00:49:51,279 Speaker 1: it is it nearly is pronounced, so it does have 880 00:49:51,320 --> 00:49:54,319 Speaker 1: an effect. You know, Chuck, this is a good one 881 00:49:54,360 --> 00:49:58,319 Speaker 1: man pain pain in the house. And if you want 882 00:49:58,320 --> 00:50:00,560 Speaker 1: to know more about pain, well, I'm not even going 883 00:50:00,600 --> 00:50:02,600 Speaker 1: to suggest what you can do. How about you just 884 00:50:02,640 --> 00:50:04,920 Speaker 1: go read up on it a little more. Uh. And 885 00:50:04,960 --> 00:50:07,160 Speaker 1: since I said that it's time for a listener meal, 886 00:50:11,280 --> 00:50:15,160 Speaker 1: I'm just gonna call this the Las Vegas Beavers. I 887 00:50:15,200 --> 00:50:17,400 Speaker 1: just got done listening to the Beaver podcast, which, by 888 00:50:17,440 --> 00:50:19,640 Speaker 1: the way, we got a lot of response on that one. 889 00:50:20,320 --> 00:50:23,600 Speaker 1: People love their beavers, especially baby beavers. Oh yeah, they're 890 00:50:23,640 --> 00:50:25,399 Speaker 1: the best. I just wanted to give you a fun 891 00:50:25,400 --> 00:50:28,040 Speaker 1: little tidbit of information. Chuck said that you can't find 892 00:50:28,360 --> 00:50:30,760 Speaker 1: or that you can find beavers almost everywhere except the desert, 893 00:50:31,160 --> 00:50:33,840 Speaker 1: which is somewhat true. Uh, they can't live out in 894 00:50:33,880 --> 00:50:38,279 Speaker 1: the open amongst the cacti. But the sizeable population of 895 00:50:38,280 --> 00:50:41,719 Speaker 1: beavers in Las Vegas is testament to their ability to 896 00:50:41,760 --> 00:50:46,120 Speaker 1: survive the heat. They're about eighty to one beavers living 897 00:50:46,120 --> 00:50:48,680 Speaker 1: in the Clark County, Wetlands, just just about twenty to 898 00:50:48,760 --> 00:50:51,520 Speaker 1: thirty minutes from the strip. It was a shock when 899 00:50:51,520 --> 00:50:53,880 Speaker 1: I first heard of this, but have since taken several 900 00:50:53,920 --> 00:50:56,959 Speaker 1: trips to see them. Thanks for all the work, enjoy 901 00:50:57,040 --> 00:51:00,160 Speaker 1: the show. That's from Josh. Very short and sweet us 902 00:51:00,160 --> 00:51:05,000 Speaker 1: from Josh uh Eretics. That's a great great first name, 903 00:51:05,160 --> 00:51:07,400 Speaker 1: great last name, Josh, and I love how that email 904 00:51:07,480 --> 00:51:10,080 Speaker 1: just kind of petered out at the end there, so 905 00:51:10,120 --> 00:51:15,200 Speaker 1: we're gonna we're His new name is Josh Peter Eretics. Okay, great. 906 00:51:15,760 --> 00:51:17,920 Speaker 1: Thanks for the email, JP, And if you want to 907 00:51:17,920 --> 00:51:20,160 Speaker 1: be like JP and send us an email, you can 908 00:51:20,200 --> 00:51:22,680 Speaker 1: do so. Wrap it up, spank it on the bottom, 909 00:51:22,680 --> 00:51:25,400 Speaker 1: and send it off to Stuff podcast at iHeart radio 910 00:51:25,520 --> 00:51:30,719 Speaker 1: dot com. Stuff you Should Know is a production of 911 00:51:30,760 --> 00:51:33,520 Speaker 1: iHeart Radios How Stuff Works. For more podcasts for my 912 00:51:33,560 --> 00:51:36,359 Speaker 1: heart Radio, visit the iHeart Radio app. Apple podcasts are 913 00:51:36,360 --> 00:51:37,960 Speaker 1: wherever you listen to your favorite shows.