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Speaker 1: All right, y'all is December thirtieth, and that means that

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Speaker 1: there are two days left in.

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Speaker 2: Twenty twenty one.

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Speaker 3: I can't believe it.

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Speaker 1: Twenty twenty one felt like it was a month long

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Speaker 1: and then at some point ten years long.

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Speaker 3: Oh a lot of the ten years long part.

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Speaker 1: So much happened this year, and so we knew that

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Speaker 1: we have to bring back our end of the year

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Speaker 1: mixtape again. It was only right, Yes, we had to

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Speaker 1: bring it back just so that we can cover some

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Speaker 1: of the topics that we weren't able to cover this year.

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Speaker 2: I mean, we just came back in Nova.

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Speaker 3: I just came back in November. We've got ten months

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Speaker 3: to get.

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Speaker 1: Through, and y'all have been asking where are y'all. So

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Speaker 1: we're going to recap everything that we weren't able to

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Speaker 1: talk about while we were away. Welcome to Dope Labs,

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Speaker 1: a weekly podcast that mixes hardcore science, pop culture, and

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Speaker 1: a healthy dosa friendship.

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Speaker 3: Twenty twenty one is rapidly coming to a close.

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Speaker 2: I can't believe we're at the end of twenty twenty

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Speaker 2: one already.

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Speaker 3: Yes, you know what time it is. Then it's time

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Speaker 3: to look back on all the biggest stories of the

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Speaker 3: Year Dope Lab style.

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Speaker 1: Yes, it is time for our annual end of the

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Speaker 1: year mixtape.

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Speaker 3: Here's how it's going to work. We will cover the

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Speaker 3: biggest stories in five different categories, and then we're gonna

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Speaker 3: do a little mini dissection for each one of those.

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Speaker 2: So here are the categories.

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Speaker 1: It's tech, health and wellness, Politics, sports.

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Speaker 2: And music.

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Speaker 3: Let's jump into tech. I thought twenty was the year

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Speaker 3: for tech, but twenty twenty one, said hold my coke.

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Speaker 1: Absolutely, with people working from home since the pandemic hit,

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Speaker 1: and then all of these new technological advances that have

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Speaker 1: been pushed to the forefront because of this new virtual

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Speaker 1: landscape that we're working in. Tech is on the tip

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Speaker 1: of everyone's tongue.

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Speaker 3: And specifically the metaverse.

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Speaker 1: At the end of October, Facebook announced that they will

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Speaker 1: now be referred to as meta.

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Speaker 3: Metaverse is just another term, and it feels foreign, just

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Speaker 3: like you. Remember when people were calling the Internet the

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Speaker 3: information Highway. I didn't know what that was.

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Speaker 1: Yes, and then I remember people calling it cyberspace. And

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Speaker 1: the first time anyone ever heard of that word was

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Speaker 1: in nineteen eighty two and a short story by William

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Speaker 1: Gibson titled Burning Chrome and then now we have metaverse

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Speaker 1: and here it is what twenty twenty one, But that

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Speaker 1: was coined by Neil Stevenson in his book snow Crash, and.

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Speaker 3: That came out in nineteen ninety two.

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Speaker 1: So it seems like the term metaverse has been around

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Speaker 1: way longer than we were member. You know, it's not

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Speaker 1: a new thing that Mark Zuckerberg just came up with.

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Speaker 1: But I still have a lot of questions about what

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Speaker 1: is all going into it. But I think the key

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Speaker 1: distinguishing feature is that a metaverse is free forming. There's

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Speaker 1: no mayor of the town, so you have people controlling games,

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Speaker 1: and even though we're all working together in harvesting corn

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Speaker 1: or whatever and these farming games, you can only do

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Speaker 1: what's been decided by the creators of the game. And

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Speaker 1: I think that's the distinguishing feature of the metaverse, is

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Speaker 1: that eventually you get on there and you do whatever.

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Speaker 1: I think they just had the first metaverse marriage recently.

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Speaker 1: It just seems like, like you said, there's a lot

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Speaker 1: more autonomy in the metaverse. You know, some of these games,

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Speaker 1: you'll be running and then you'll be running into an

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Speaker 1: invisible wall because no more game. Then you reached the

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Speaker 1: bounds of the game. The metaverse, there's no such thing.

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Speaker 1: You can do what you want.

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Speaker 3: I think we got to really give our props to

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Speaker 3: verse as the predicate because people have been using it

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Speaker 3: all around the Marvel Verse, you Verse, and the dccomic verse,

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Speaker 3: and so the idea of creating these universes or ecosystems,

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Speaker 3: if you will.

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Speaker 2: Is not new.

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Speaker 3: Like you said, TT and Facebook isn't the first player here.

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Speaker 3: They're just a player with the most money, the player

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Speaker 3: that really needed a rebrand after being called out for

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Speaker 3: terrible practices.

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Speaker 1: We all know things that are kind of like meta.

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Speaker 1: When we were growing up, it was SIMS, and then

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Speaker 1: there's things now like Roadblocks and Fortnite, where you're in

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Speaker 1: this world where everybody can create their own experiences but

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Speaker 1: then also interact with each other, where it will feel

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Speaker 1: like a hybrid of our online social experiences sometimes expanded

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Speaker 1: into the physical world. So imagine you're walking around and

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Speaker 1: then you can see something from the metaverse in front

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Speaker 1: of you and interact with it. So it creates this

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Speaker 1: immersive experience with other people even when you can't be together.

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Speaker 3: And it feels like we've been leaning this way for

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Speaker 3: a long time before Sims. It was the time of

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Speaker 3: got something that continued to go on and on, whether

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Speaker 3: you were playing with it or not.

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Speaker 1: Yes, I remember when my fifth grade teacher took my

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Speaker 1: nano baby from me and she held it in her

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Speaker 1: desk overnight because I was playing with it during class.

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Speaker 1: I got that nano baby back the next day and

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Speaker 1: I had to put them in the hospital for days.

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Speaker 1: I cried, Oh my gosh, the own version of the

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Speaker 1: nick You the nano baby intensive care unit. But you

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Speaker 1: were able to rehab so your nano baby got out.

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Speaker 2: Yeah. But then my mother was like, enough of this.

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Speaker 3: Enough is enough. I know that's right, missus. Shodia get

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Speaker 3: t t together, but so tamagaji nano baby, Sims. You

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Speaker 3: remember when I was playing that farming game on my

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Speaker 3: iPod Touch, Yes, okay, and we were going out and

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Speaker 3: my mom and got Mama behind the house and I

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Speaker 3: was like, please harvest this corn while we're gone. Okay,

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Speaker 3: I need you to harvest these crops.

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Speaker 1: We've all been interacting with things that were meta adjacent

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Speaker 1: or really just the meta itself. But now Facebook is

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Speaker 1: trying to formalize it where everybody's going.

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Speaker 2: To the same place. Do you think that people are

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Speaker 2: gonna be interacting with the.

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Speaker 3: Metaverse absolutely, Listen. I've seen some articles where basically they're

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Speaker 3: already fumbling the ball. Okay, they're interacting, but why would

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Speaker 3: you create the exact same systems that exist here and

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Speaker 3: are terrible in a metaverse? Yeah, people are buying property,

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Speaker 3: buying it up. That's fake scarcity. Don't we have enough

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Speaker 3: gigabytes to go around? Honestly, isn't there enough space for

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Speaker 3: everybody to have a plot of land and live?

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Speaker 2: Why recreate capitalism.

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Speaker 1: And the drive for them to buy this land and

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Speaker 1: buying it so early in this whole metaverse is so

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Speaker 1: that they can establish themselves as the socioeconomic elite inside

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Speaker 1: of the metaverse. So when it comes time and more

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Speaker 1: people start to go to the metaverse, they already own

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Speaker 1: a lot of land, they own property, they've already established

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Speaker 1: businesses so that they can be wealthy within the metaverse.

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Speaker 3: But I feel like, if the metaverse is digital, there

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Speaker 3: should be enough space.

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Speaker 2: For all of us. Yeah, pan left make more room.

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Speaker 1: I have seen my niece and nephew play roadblocks and

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Speaker 1: interacting in this roadblocks world where there's a ton of

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Speaker 1: other people playing and interacting with each other, people are

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Speaker 1: building houses. It really makes me wonder about what our

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Speaker 1: futures look like. But I also have heard that some

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Speaker 1: people are speculating that Generation Alpha, so I'm not talking

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Speaker 1: about millennials like me and you are or gen Zer's.

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Speaker 1: Generation Alpha is folks that are born between twenty ten

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Speaker 1: and twenty twenty four, so they're all children right now

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Speaker 1: that maybe when they get to be adults or nearing adulthood,

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Speaker 1: they'll start to push back on all of this technology

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Speaker 1: that is seemingly supposed to be connecting us more, but

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Speaker 1: not in a human one to one connection. They're going

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Speaker 1: to start to say, no, I am opting for more

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Speaker 1: human conde rather than virtual connection.

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Speaker 2: Ah.

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Speaker 1: So it'll be really interesting to see what happens, because

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Speaker 1: to me, it feels like we're going warp speed towards

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Speaker 1: everybody never leaving their houses and having virtual reality goggles

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Speaker 1: on all the time. But maybe Generation Alpha will be

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Speaker 1: the ones to help swing the pendulum the other way.

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Speaker 2: Okay, let's jump into health.

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Speaker 3: There's so much going on in the health and wellness front.

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Speaker 3: We spent the early part of twenty twenty one talking

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Speaker 3: about vaccines and then variants, and then the omicron variant,

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Speaker 3: which we keep learning new things about every day. I

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Speaker 3: think it goes without saying nobody deserves to get sick, right,

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Speaker 3: I think illness is just part of nature. And everybody

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Speaker 3: can't afford to stay home unless you're independently wealthy, and

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Speaker 3: if you are, I will send my cash app. But

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Speaker 3: you know, people have to live and for some people

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Speaker 3: getting together with others that has its own benefits. And

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Speaker 3: so when everybody's making their own individuals assessments, it's really

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Speaker 3: hard because the transmissibility seems through the roof on omicron.

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Speaker 3: And I think we'll just keep learning more every day.

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Speaker 2: Yeah.

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Speaker 1: The last thing that I heard, which I mean by

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Speaker 1: the time folks listening to this, it might be different,

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Speaker 1: was that omicron is on pace to be the most

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Speaker 1: dominant variant in the UK by the top of twenty

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Speaker 1: twenty two, more than any delta cases, more than any

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Speaker 1: of the other cases that we've seen, which.

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Speaker 2: Is mind boggling to me and a little bit scary.

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Speaker 3: And right now there's a lot of conversations saying, oh,

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Speaker 3: it's milder, but it's like, hey, if transmissibility is high

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Speaker 3: and it's harder for it to infect tissues, and the

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Speaker 3: lung compared to the broncos.

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Speaker 2: Then there's just all these things.

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Speaker 3: We haven't had enough time with it, and that's the

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Speaker 3: tricky part. We don't get to press the pause button

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Speaker 3: until we can get more data. So it's just really

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Speaker 3: tough and really changing daily by the hour, New update,

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Speaker 3: new update. But there was some good development and that

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Speaker 3: was with those COVID pills.

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Speaker 2: Yes, I saw that.

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Speaker 1: It seems really interesting because I think with a lot

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Speaker 1: of these things, everybody's looking for if I get sick,

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Speaker 1: what do I do? And so it seems like there

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Speaker 1: are two new COVID pills that are going to be

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Speaker 1: hit in the market and are expected to work against

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Speaker 1: all versions, all the variants of the virus.

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Speaker 3: It feels like there are some things that people are

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Speaker 3: missing when it comes to COVID in general, even though

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Speaker 3: we're in year three of it, especially when it comes

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Speaker 3: to omicron and one of those things is that this

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Speaker 3: is highly transmissible, and so it's not a matter of

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Speaker 3: whether or not you're going to get exposed, but how

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Speaker 3: prepared you're going to be when you get exposed. And

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Speaker 3: then because it's so highly transmissible, that means that denominator

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Speaker 3: number when we talk about oh it's mild, it's often mild.

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Speaker 3: And so if we say, okay, let's say only ten

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Speaker 3: percent of cases are severe, ten percent of a really

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Speaker 3: big number is still a really big number, and that

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Speaker 3: has the potential to overwhelm our hospital systems. And so

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Speaker 3: that's not just folks who are dealing with COVID, but

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Speaker 3: folks who are having other health situations going on as well.

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Speaker 3: And so that's why this pill is so important because

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Speaker 3: if we think about the moderate to severe cases, which

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Speaker 3: we know we will see more of those just by

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Speaker 3: the sheer denominator rising because of the transmissibility of omicron,

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Speaker 3: this has the potential to clear folks out of the

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Speaker 3: hospital much quicker, so we can continue to take care

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Speaker 3: of routine health things that need to be managed that

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Speaker 3: our health system just isn't equipped to handle alongside COVID

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Speaker 3: without intervention. So now we have a second lot of defense.

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Speaker 3: We have vaccines and we have COVID pills if you

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Speaker 3: do get COVID, and people who are vaccinated can still

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Speaker 3: get COVID. Right, And so it's not either or is.

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Speaker 3: We need all the tools we can right now and and.

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Speaker 1: Right And it's really exciting because even with just some

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Speaker 1: of the preliminary results, it's showing that one of these

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Speaker 1: drugs has been eighty five percent effective when taken within

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Speaker 1: five days of the start of symptoms.

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Speaker 2: So that's really exciting.

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Speaker 3: But something started to happen in the pandemic in twenty

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Speaker 3: two and it really bled over to twenty twenty one.

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Speaker 3: A lot of people started to go the way of

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Speaker 3: Jessica Rabbit.

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Speaker 1: Yes, Brazilian butt lifts, or as it's colloquially called bbls.

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Speaker 3: Yes, Buffy the Body really set the trend for y'all.

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Speaker 2: Okay, if you.

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Speaker 1: Know Buffy the Body, get on Instagram and comment under

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Speaker 1: our posts.

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Speaker 3: Yes, let me know that you know. Okay, she's the og.

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Speaker 2: She is.

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Speaker 3: That's who Jessica Rabbit could only hope to be. And

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Speaker 3: plastic surgery in general has been going up.

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Speaker 2: Yes, So with.

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Speaker 1: The BBL procedure, it's a two part procedure. First, the

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Speaker 1: doctor performs a liposection, so they're using a machine that

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Speaker 1: pulls out the fat from the patient from areas of

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Speaker 1: your body where you have fat where you don't really

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Speaker 1: want it.

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Speaker 2: And then the fat.

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Speaker 1: Is put into a centrifuge, which in this case is

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Speaker 1: a device that's used to separate out the fat from

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Speaker 1: any other fluids like blood, so that they can take

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Speaker 1: that fat and then reinject it back into the patient

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Speaker 1: in their posterior.

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Speaker 3: Plastic surgery in general has been going up because people

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Speaker 3: are looking at our faces. You know, we're on Zoom,

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Speaker 3: We're looking at ourselves much more. We're not meant to

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Speaker 3: look at ourselves as much. And really there was some

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Speaker 3: foreshadowing because in Lab two Edge of Snatch, doctor Monty

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Speaker 3: Oyd Harris told us exactly.

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Speaker 4: That there's been no other time probably in the history

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Speaker 4: of human civilization, right, that folks are engaging and looking

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Speaker 4: at themselves as much as they are now. So I

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Speaker 4: started to see a growing and growing misalignment related to

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Speaker 4: this notion of self image and self fact, Right, who

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Speaker 4: are you really at your core? And then what's this

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Speaker 4: layer of image that's on this and is this misaligned?

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Speaker 2: Their aligned?

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Speaker 4: And so as the misalignment started to get bigger, particularly

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Speaker 4: with patients that were looking for the changing their nose

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Speaker 4: and changing their lips, you know, I was like, this

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Speaker 4: doesn't really add up anymore for me.

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Speaker 1: You know what, Also, crazy Zoom isn't helping because you

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Speaker 1: can put a filter on yourself in zoom. Right, I

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Speaker 1: was on a zoom call and I added eyelashes and lipstick.

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Speaker 1: I looked fabulous. That's not how I looked in real life.

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Speaker 1: So once I got off Zoo, I was like, oh.

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Speaker 3: And I'm all about people looking the way they want

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Speaker 3: to look, looking in ways that make them feel good.

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Speaker 3: I think the bone I have to pick with the

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Speaker 3: BBL is the risk that's associated. Yeah, so it's really popular,

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Speaker 3: but it's also the deadliest. So roughly two in every

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Speaker 3: six thousand BBLS results in death. This procedure is dangerous

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Speaker 3: not just because you're moving fat around in the body,

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Speaker 3: but because it's being put in the butt, which has

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Speaker 3: a lot of vasculature. So what can happen is you

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Speaker 3: can easily get fat in a blood vessel and boom,

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Speaker 3: fats in your heart.

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Speaker 2: Now.

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Speaker 1: Yeah, And I think that a part of the problem

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Speaker 1: is that a lot of these things are being done

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Speaker 1: in secrecy, and people are traveling outside of the country

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Speaker 1: to try and get these procedures done because there are

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Speaker 1: a lot of plastic surgeons who refuse to do bbls,

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Speaker 1: and so folks are traveling outside of the country to

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Speaker 1: find doctors who are willing to risk it so that

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Speaker 1: you can get the body that you want. And I

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Speaker 1: think a lot of it that makes it really tricky

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Speaker 1: is that there's a like you said, people going to

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Speaker 1: doctors trying to find something that affordable. B Fewer plastic

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Speaker 1: surgeons are doing these procedures because of the risk involved.

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Speaker 2: So what you.

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Speaker 3: Get is doctors who may not be specialists that are

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Speaker 3: doing these procedures. So now you have something that's high

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Speaker 3: risk and somebody who's not specifically trained for it. That's

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Speaker 3: a nasty combination. And third, because people are traveling, they're

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Speaker 3: playing it kind of loosey goosey to me. With the

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Speaker 3: post operation care. There's a lot of post operation care

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Speaker 3: that has to be done after a BBL, so like

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Speaker 3: lymphatic draining and checking to make sure there's no infection.

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Speaker 3: So if you've traveled, if you can't stay in that

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Speaker 3: same place or there's nowhere for you to stay to

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Speaker 3: get post oop care, you've got to travel back, which

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Speaker 3: makes you susceptible to infection.

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Speaker 1: Yeah, getting on a plane, your body is being battered

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Speaker 1: up there, okay, because the air pressure is different, you're

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Speaker 1: at a different altitude. Our bodies are really fighting while

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Speaker 1: we're up in planes, and so if you've undergone such

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Speaker 1: a major surgery, anything can happen. And yeah, because you

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Speaker 1: are putting your body in this distressed state. While you're

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Speaker 1: in a distressed state.

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Speaker 3: And if you're flying commercial, you're sitting on that BBL,

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Speaker 3: which you probably shouldn't be doing.

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Speaker 2: You're not supposed to You're supposed to be laying flat

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Speaker 2: on your stomach.

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Speaker 3: I believe in doing what makes you feel good.

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Speaker 2: If you like it, I love it.

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Speaker 3: But I also want you to know what your risks are.

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Speaker 3: And so I think it's really easy to see the

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Speaker 3: end product and be like, yes, that's what I want,

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Speaker 3: but I just want you to know the in between

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Speaker 3: stops as.

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Speaker 1: Well, and not to mention these procedures aren't covered by insurance. Yes,

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Speaker 1: so a lot of people are spending a lot of money.

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Speaker 3: It's so important to find a surgeon that you trust.

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Speaker 3: So do your googles, read the testimonials, ask somebody that

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Speaker 3: you know they got to BBL multiple forms of information.

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Speaker 3: That's the way to go.

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Speaker 1: All right, let's take a break, but when we get back,

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Speaker 1: we'll dive into our last three categories for our twenty

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Speaker 1: twenty one end of the year mixtape starting with politics.

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Speaker 3: We're back and before we dive into our twenty twenty

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Speaker 3: one mixtape, what are we dissecting on next week's lab tt.

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Speaker 1: Next week, we're starting a special series for the new

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Speaker 1: year that's focused on health, wellness, and setting yourself up

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Speaker 1: for success in twenty twenty two.

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Speaker 3: And our first episode is going to be all about sleep.

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Speaker 2: I love sleeping.

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Speaker 3: We all know that again the good night's sleep has

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Speaker 3: major health benefits and most of us wish we could

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Speaker 3: get more of it. So we're talking to doctor Jarde

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Speaker 3: and Jean Luis all about how to get better sleep,

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Speaker 3: plus some really interesting insights on sleep disparities. Some folks

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Speaker 3: are more vulnerable to bad sleep than others. I think

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Speaker 3: that's me. Don't miss it.

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Speaker 2: All.

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Speaker 1: Right, back to our twenty twenty one end of the

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Speaker 1: year mixtape, and our next category is politics. Twenty twenty

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Speaker 1: one has been a political thriller in real life honesty,

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Speaker 1: like somebody just dropped us into multiple movies.

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Speaker 2: You can't write a better book.

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Speaker 3: We started the top of the year with insurrection. How

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Speaker 3: can we have a parade and overthrow the government all

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Speaker 3: in one A parade, a riot, and the collapse of democracy.

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Speaker 2: Yeah, and it seemingly the president was in on it,

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Speaker 2: the orchestrator.

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Speaker 3: It just really got wild. So there's that. So in

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Speaker 3: March the Derek Chauvin trial began and that went on

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Speaker 3: for a while up until June twenty fifth, when the

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Speaker 3: judge sentenced Choven to twenty two and a half years

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Speaker 3: in prison, and two thirds of that has to be

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Speaker 3: served before he's eligible for parole.

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Speaker 1: In September we had the twentieth anniversary of nine to eleven,

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Speaker 1: which is really crazy. It feels I don't know, if

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Speaker 1: it feels like it was twenty years ago.

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Speaker 2: No.

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Speaker 1: And just before then, on August thirtieth of twenty twenty one,

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Speaker 1: the US Armed Forces withdrew troops from Afghanistan. And also

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Speaker 1: in September, in Texas, they passed a law called the

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Speaker 1: Texas Heartbeat Act, and this is the most restrictive abortion

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Speaker 1: law in the nation for abortion access. This law bans

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Speaker 1: abortions at around six weeks, which is before most people

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Speaker 1: even know they're pregnant.

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Speaker 3: And the wild aspect of that law is that anybody,

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Speaker 3: whether they're related to you or not, if they think

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Speaker 3: you are performing or facilitating an illegal abortion, they can

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Speaker 3: sue you for a minimum of ten thousand dollars in damages.

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Speaker 2: What is happening?

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Speaker 3: You know, when you really look back on it, it

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Speaker 3: kind of feels like the political theme of twenty twenty

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Speaker 3: one is around civil rights. Yes, you know, because it

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Speaker 3: felt like maybe there was some progress when you think

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Speaker 3: back to the Derek Chauvin trial and the response to

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Speaker 3: you know, police violence and brutality. But then it felt

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Speaker 3: like we took a step back because in November, Kyle

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Speaker 3: Rittenhouse was found not guilty, even though it's factually known

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Speaker 3: that he shot three people and killed two of them

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Speaker 3: at a protest against police violence.

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Speaker 1: And he went to this protest with an AR fifteen

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Speaker 1: style rifle that he purchased illegally, and he also crossed

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Speaker 1: state lines with that illegal rifle. And there's also the

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Speaker 1: whole restricting of voting rights and the campaigns for that,

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Speaker 1: all the civil rights things that we thought were over.

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Speaker 1: It's like we take a step forward, we take a

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Speaker 1: step back, we take a step forward. Think about the

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Speaker 1: McMichaels who killed a mad Aubrey. They were convicted of murder.

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Speaker 1: That was in November, and that felt like a step forward.

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Speaker 1: It felt like a step forward, but here we are

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Speaker 1: in December back of the Supreme Court with Dobbs versus

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Speaker 1: Jackson Women's Health Organization. So this is a case that

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Speaker 1: could be the biggest abortion case the Supreme Court here

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Speaker 1: since Roe versus eight. Yeah, it's really crazy, but I'm

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Speaker 1: trying to keep hope alive. I'm trying to be optimistic

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Speaker 1: about a lot of these things. Like you said, it

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Speaker 1: feels like, you know, two steps forward, one step back,

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Speaker 1: sometimes ten steps back, and it can be very draining.

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Speaker 3: I'm tired of people doing a Q shouffuled with my rights.

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Speaker 3: But honestly, this really feels like just the tip of

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Speaker 3: the iceberg for politics. We couldn't put everything in the show,

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Speaker 3: so be sure to check out our show notes at

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Speaker 3: dopelauspodcast dot com to see all of the stuff that

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Speaker 3: happened this year.

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Speaker 1: The Summer Olympics happened this summer, and it was very

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Speaker 1: exciting because it had been postponed a full year because

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Speaker 1: of the pandemic. Even though there weren't any spectators in

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Speaker 1: the stands per se, it was still really exciting to see.

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Speaker 3: Yeah, it just feels weird to have the Summer Olympics

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Speaker 3: in an odd number year.

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Speaker 2: And having the Winter Olympics right around the corner.

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Speaker 3: We saw athletes stand up for themselves in a really

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Speaker 3: big way this year.

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Speaker 1: During the Summer Olympics, we had Simone Biles pushing back

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Speaker 1: really significantly when it came to her mental health and

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Speaker 1: her ability to perform as a result of her mental

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Speaker 1: health and prioritizing herself.

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Speaker 3: And that was right on the heels of Naomi Osaka

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Speaker 3: was drawing from the French Open due to depression and

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Speaker 3: mental health concerns as well. So it felt like we've

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Speaker 3: really had some momentum, and a lot of other athletes

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Speaker 3: were rallying behind them and co signing, saying, yes, we

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00:22:07,080 --> 00:22:09,920
Speaker 3: agree with this, and it's so important to be able

443
00:22:09,960 --> 00:22:13,240
Speaker 3: to stand up for yourself and say, my mental health

444
00:22:13,320 --> 00:22:15,639
Speaker 3: is just as important as my physical health when it

445
00:22:15,680 --> 00:22:16,679
Speaker 3: comes to my performance.

446
00:22:16,840 --> 00:22:19,439
Speaker 1: What some mobiles are struggling with during the Olympics is

447
00:22:19,480 --> 00:22:22,119
Speaker 1: what's called the twisties, and that's when the mind and

448
00:22:22,280 --> 00:22:24,040
Speaker 1: body don't connect.

449
00:22:24,480 --> 00:22:25,800
Speaker 2: And so while she.

450
00:22:25,920 --> 00:22:29,280
Speaker 1: Was flying through the sky as she does and doing

451
00:22:29,320 --> 00:22:31,800
Speaker 1: all of these flips and things, she would not be

452
00:22:31,880 --> 00:22:34,400
Speaker 1: able to figure out what's up, what's down where she

453
00:22:34,680 --> 00:22:37,240
Speaker 1: was in the three D space, and so that was

454
00:22:37,240 --> 00:22:39,959
Speaker 1: affecting her ability to be able to land safely, And

455
00:22:40,040 --> 00:22:44,000
Speaker 1: so if she's experiencing that, you would think everyone would say, Okay,

456
00:22:44,040 --> 00:22:48,040
Speaker 1: that's very dangerous. But people were saying, no, you're a

457
00:22:48,119 --> 00:22:51,159
Speaker 1: disappointment and you should be pushing yourself. And it's not

458
00:22:51,240 --> 00:22:54,760
Speaker 1: about her physical strength, it's about her mind not being

459
00:22:54,760 --> 00:22:55,359
Speaker 1: able to do.

460
00:22:55,320 --> 00:22:56,720
Speaker 2: The things that she normally can do.

461
00:22:57,320 --> 00:23:00,000
Speaker 1: And I think what's most important when she's doing those

462
00:23:00,040 --> 00:23:01,560
Speaker 1: flips is that she lands safely.

463
00:23:01,720 --> 00:23:04,800
Speaker 3: Yes, do you know what type of positional self awareness

464
00:23:04,800 --> 00:23:06,760
Speaker 3: you have to have to do those stunts that Simone

465
00:23:06,800 --> 00:23:09,159
Speaker 3: Boles is doing. I don't like to go from the

466
00:23:09,200 --> 00:23:12,160
Speaker 3: couch to the kitchen When I stand up too fast

467
00:23:12,160 --> 00:23:14,000
Speaker 3: and sometimes I feel dizzy, I sit back down.

468
00:23:14,920 --> 00:23:19,440
Speaker 1: If you can't spin round in the sky five times

469
00:23:19,480 --> 00:23:21,120
Speaker 1: and land on your feet, I don't want to hear

470
00:23:21,119 --> 00:23:22,719
Speaker 1: nothing you got to say about someone bolls.

471
00:23:22,920 --> 00:23:26,520
Speaker 3: Simone Bowles isn't the only athlete making a big stance,

472
00:23:27,560 --> 00:23:30,399
Speaker 3: shaking up things, making it drop.

473
00:23:30,680 --> 00:23:32,160
Speaker 2: I love these metaphors.

474
00:23:32,240 --> 00:23:37,399
Speaker 3: Yes, our new favorite athlete, Megan the Stallion, really shook

475
00:23:37,440 --> 00:23:39,960
Speaker 3: the table with that Nike deal, and that takes us

476
00:23:40,040 --> 00:23:41,719
Speaker 3: right from sports into music.

477
00:23:42,040 --> 00:23:50,200
Speaker 1: Yes, a lot has happened with music over the last year.

478
00:23:50,359 --> 00:23:55,919
Speaker 2: Olivia Rodrigo made her big splash and took over the

479
00:23:56,080 --> 00:23:58,159
Speaker 2: radio and every form of media.

480
00:23:58,320 --> 00:24:01,080
Speaker 1: You couldn't go five minute It's without hearing an Olivia

481
00:24:01,200 --> 00:24:05,160
Speaker 1: Rodrigo song. Fionce became the most awarded woman in Grammy

482
00:24:05,240 --> 00:24:08,600
Speaker 1: history and became a Grammy Award winning rapper herself with

483
00:24:08,720 --> 00:24:11,480
Speaker 1: her song with Magdae Stallion. Yes, we had the death

484
00:24:11,600 --> 00:24:13,680
Speaker 1: of DMX, which was really really sad.

485
00:24:14,560 --> 00:24:17,160
Speaker 3: I remember exactly where I was when that happened. Where

486
00:24:17,160 --> 00:24:20,840
Speaker 3: were you at an outdoor bar in DC. Shout out

487
00:24:20,880 --> 00:24:23,359
Speaker 3: to Abro he was bartending that bar played like all

488
00:24:23,440 --> 00:24:27,240
Speaker 3: DMX after that, and everybody was just all in the fields.

489
00:24:27,320 --> 00:24:27,520
Speaker 2: You know.

490
00:24:27,600 --> 00:24:29,879
Speaker 3: It was sad, but it was also a celebration of

491
00:24:29,920 --> 00:24:33,320
Speaker 3: his life as well. Yes, I mean, what a time

492
00:24:33,359 --> 00:24:36,080
Speaker 3: to be alive, to be able to experience DMX and

493
00:24:36,200 --> 00:24:37,320
Speaker 3: that amazing music.

494
00:24:37,440 --> 00:24:39,639
Speaker 2: Oh my gosh hmm.

495
00:24:39,880 --> 00:24:42,240
Speaker 1: If you don't have DMX and the Rough Riders in

496
00:24:42,280 --> 00:24:44,240
Speaker 1: your Spotify playlists, make it happen.

497
00:24:44,560 --> 00:24:48,160
Speaker 2: And also Adele, after what felt like too.

498
00:24:48,040 --> 00:24:51,400
Speaker 1: Long Yes of being Away, came back with her new

499
00:24:51,480 --> 00:24:56,200
Speaker 1: album thirty and really just took over everybody's lives. I mean,

500
00:24:56,240 --> 00:25:00,160
Speaker 1: everybody's just been screamed, crying and sobbing, even though they're

501
00:25:00,160 --> 00:25:04,080
Speaker 1: perfectly happy. Yeah, you know that effect on people was

502
00:25:04,080 --> 00:25:07,200
Speaker 1: singing good deal. Listening to Adele and her new album,

503
00:25:07,240 --> 00:25:09,359
Speaker 1: there were so many moments where you know, when the

504
00:25:09,960 --> 00:25:12,399
Speaker 1: hairs just stand up all over your body because you

505
00:25:12,520 --> 00:25:17,200
Speaker 1: have so much emotion. I learned what that actually is.

506
00:25:17,200 --> 00:25:19,760
Speaker 1: There's something chemical going on. I'm sure you already knew, ze,

507
00:25:19,920 --> 00:25:23,320
Speaker 1: but these things always blow my mind. It's something called

508
00:25:23,440 --> 00:25:26,919
Speaker 1: free song. There's actually something chemical going on in your body.

509
00:25:27,320 --> 00:25:30,000
Speaker 1: And our friend Cole Kushna, he has a show called

510
00:25:30,040 --> 00:25:32,720
Speaker 1: Keynotes where he takes an aspect of music and he

511
00:25:32,840 --> 00:25:35,320
Speaker 1: really gets into the nitty gritty about it, and he

512
00:25:35,440 --> 00:25:39,639
Speaker 1: did an entire episode on free song, which is the

513
00:25:39,760 --> 00:25:42,919
Speaker 1: chills that you get when you experience certain emotions. And

514
00:25:42,960 --> 00:25:45,960
Speaker 1: so what's happening is that our brains are constantly trying.

515
00:25:45,720 --> 00:25:46,560
Speaker 2: To predict the future.

516
00:25:46,720 --> 00:25:48,879
Speaker 1: But with music, as you're going through a song, it

517
00:25:48,960 --> 00:25:51,560
Speaker 1: might have the same you know, melodies, the same core

518
00:25:51,640 --> 00:25:54,159
Speaker 1: progressions that's just repeated over and over again, and this

519
00:25:54,280 --> 00:25:59,000
Speaker 1: anticipation is building, and then once something memorable or different happens,

520
00:25:59,240 --> 00:26:01,960
Speaker 1: there is a dopamine release in our brain, which is

521
00:26:02,000 --> 00:26:05,600
Speaker 1: our reward, and that then leads to the chills. And

522
00:26:05,680 --> 00:26:08,280
Speaker 1: so if you're listening to a song and you do

523
00:26:08,320 --> 00:26:10,760
Speaker 1: get the chills, try and think about what is actually

524
00:26:10,760 --> 00:26:13,320
Speaker 1: happening in the song. Is it a part where the

525
00:26:13,359 --> 00:26:16,440
Speaker 1: singer is going into a really beautiful falsetto was there a.

526
00:26:16,440 --> 00:26:17,320
Speaker 2: Change in the melody?

527
00:26:17,760 --> 00:26:21,439
Speaker 1: And usually, based on what I learned listening to that

528
00:26:21,520 --> 00:26:25,440
Speaker 1: podcast episode, it aligns perfectly with something like that when

529
00:26:25,480 --> 00:26:27,800
Speaker 1: I get the chills and when something is changing in the.

530
00:26:27,720 --> 00:26:30,040
Speaker 3: Song, and once you have that reward, your brain wants

531
00:26:30,040 --> 00:26:32,080
Speaker 3: to do that over and over again. I know for me,

532
00:26:32,600 --> 00:26:35,960
Speaker 3: I feel that in scary movies, like that anticipation in

533
00:26:36,000 --> 00:26:38,520
Speaker 3: the suspense building and when it's something going to happen.

534
00:26:39,040 --> 00:26:41,679
Speaker 3: Love it. You know who else came back though, and

535
00:26:41,760 --> 00:26:43,399
Speaker 3: I was waiting for them. I was waiting for them

536
00:26:43,400 --> 00:26:45,280
Speaker 3: to the front door. Silk Sonic.

537
00:26:47,200 --> 00:26:48,119
Speaker 2: Yeah, Silk Sonic.

538
00:26:48,200 --> 00:26:51,439
Speaker 1: They come out with like one song and just we

539
00:26:51,520 --> 00:26:54,080
Speaker 1: get our whole lives and then we don't hear from

540
00:26:54,119 --> 00:26:55,840
Speaker 1: them and they come back with another banger.

541
00:26:55,880 --> 00:26:56,400
Speaker 2: I love it.

542
00:26:56,440 --> 00:27:00,600
Speaker 3: Silk Sonic got a huge bump. Everybody was talking about

543
00:27:00,600 --> 00:27:03,600
Speaker 3: it and I remember the way I found out that

544
00:27:03,640 --> 00:27:07,200
Speaker 3: the album was released is on Twitter or somewhere. Maybe

545
00:27:07,240 --> 00:27:10,359
Speaker 3: somebody text me and said did you listen to and

546
00:27:10,400 --> 00:27:14,639
Speaker 3: it said a e w SS And I was like,

547
00:27:14,680 --> 00:27:17,000
Speaker 3: what is that? An evening with Silk Sonic.

548
00:27:18,960 --> 00:27:22,640
Speaker 2: Acronyms? Like it's just acronyms already.

549
00:27:22,119 --> 00:27:26,600
Speaker 3: Already, but you know, it was giving me all the

550
00:27:26,680 --> 00:27:30,520
Speaker 3: vibes of the groups. I like, uh huh. I want

551
00:27:30,520 --> 00:27:34,359
Speaker 3: to feel like the Delphonics are back and they're in style.

552
00:27:34,600 --> 00:27:35,680
Speaker 3: You know that's my group.

553
00:27:35,680 --> 00:27:37,200
Speaker 2: Do you have a favorite Delphonic song?

554
00:27:37,480 --> 00:27:40,560
Speaker 3: Mmm, it's hard, but I have a beautiful winter playlist

555
00:27:40,560 --> 00:27:44,080
Speaker 3: and it has Al Green, El DeBarge, Curtis Mayfield, Donnie Hathaway,

556
00:27:44,119 --> 00:27:47,320
Speaker 3: Reatha Franklin, Eddie Kendricks. The Delphonic song that I like

557
00:27:47,400 --> 00:27:48,679
Speaker 3: on here is I Gave to You.

558
00:27:49,800 --> 00:27:53,919
Speaker 2: So that seventies vibe is coming through with Silk Sonic.

559
00:27:54,040 --> 00:27:56,120
Speaker 3: Put on your bell bottoms and platforms.

560
00:27:56,359 --> 00:28:00,680
Speaker 2: What is that? Is it hard? I wish they see

561
00:28:00,720 --> 00:28:04,520
Speaker 2: tt right now. She's just playing every instrument at once.

562
00:28:06,440 --> 00:28:08,520
Speaker 2: It just feels super seventies, right.

563
00:28:08,560 --> 00:28:11,720
Speaker 1: I mean, they definitely amp up the seventies feel of

564
00:28:11,720 --> 00:28:13,560
Speaker 1: it with the way that they dress when they perform,

565
00:28:13,760 --> 00:28:17,359
Speaker 1: and the just the look of their videos always feel

566
00:28:17,600 --> 00:28:21,800
Speaker 1: super seventies. But there's something about the music that just

567
00:28:21,920 --> 00:28:26,440
Speaker 1: makes everyone feel good, like a good seventies jam does.

568
00:28:26,480 --> 00:28:28,600
Speaker 3: And even if you don't know exactly what it is,

569
00:28:28,760 --> 00:28:29,560
Speaker 3: you can feel it.

570
00:28:29,840 --> 00:28:31,480
Speaker 2: You can feel it when it washes over you.

571
00:28:31,600 --> 00:28:34,040
Speaker 3: Yes, I wish we could have some seventies style music

572
00:28:34,080 --> 00:28:40,320
Speaker 3: come in right now, yes, Rob right, Yes.

573
00:28:40,160 --> 00:28:44,360
Speaker 1: It's these wind chimes, like the electric sitar, things like that.

574
00:28:44,560 --> 00:28:47,840
Speaker 1: I feel like our quintessential seventies music.

575
00:28:48,120 --> 00:28:48,440
Speaker 3: Yes.

576
00:28:53,000 --> 00:28:55,120
Speaker 2: Is there something you're looking forward to in twenty twenty two?

577
00:28:56,120 --> 00:29:02,040
Speaker 3: It's hard. I don't feel hopeful. Oh no, I'm looking forward.

578
00:29:01,840 --> 00:29:03,320
Speaker 2: To humans being better.

579
00:29:03,640 --> 00:29:06,160
Speaker 1: Yeah, that's always my hope going into every year. I

580
00:29:06,160 --> 00:29:10,720
Speaker 1: think I'm hoping for us to really turn a corner

581
00:29:10,760 --> 00:29:13,320
Speaker 1: with this pandemic and for us to creep closer and

582
00:29:13,360 --> 00:29:17,000
Speaker 1: closer to things getting back to quote unquote normal. I

583
00:29:17,080 --> 00:29:19,880
Speaker 1: know that with the omicron variant that a lot of

584
00:29:19,960 --> 00:29:23,640
Speaker 1: travel has been disrupted, and especially around the holiday season,

585
00:29:23,680 --> 00:29:26,280
Speaker 1: that was tough for a lot of people. But that's

586
00:29:26,280 --> 00:29:28,240
Speaker 1: my hope for twenty twenty two, is that at some

587
00:29:28,400 --> 00:29:32,440
Speaker 1: point folks can start to resume their lives and we

588
00:29:32,440 --> 00:29:34,880
Speaker 1: could put this pandemic in the rear view mirror.

589
00:29:40,000 --> 00:29:42,440
Speaker 2: So for one thing this week, we are going to run.

590
00:29:42,280 --> 00:29:45,040
Speaker 1: Through some of our favorite things from a lot of

591
00:29:45,040 --> 00:29:48,160
Speaker 1: different categories. So first we're gonna start off with movies.

592
00:29:48,240 --> 00:29:50,080
Speaker 2: Is the KEYA? What was your favorite movie of twenty.

593
00:29:50,000 --> 00:29:50,600
Speaker 3: You already know.

594
00:29:50,880 --> 00:29:57,480
Speaker 2: I already know Dune. I wasn't even gonna watch this movie.

595
00:29:57,560 --> 00:29:58,640
Speaker 3: You weren't gonna watch it?

596
00:29:58,840 --> 00:29:59,480
Speaker 2: No, I didn't.

597
00:29:59,520 --> 00:30:02,280
Speaker 1: I was like, I love Zindia, shout outs to my

598
00:30:02,320 --> 00:30:04,240
Speaker 1: girls India, but I was.

599
00:30:04,200 --> 00:30:09,720
Speaker 3: Just like, I don't know what on my recommendation. Legitimately, Oh,

600
00:30:09,840 --> 00:30:10,800
Speaker 3: I feel so honored.

601
00:30:11,320 --> 00:30:13,800
Speaker 2: Yeah, I only watched because you said you have to watch.

602
00:30:13,920 --> 00:30:16,720
Speaker 3: I think Dune and The Harder They Fall I really

603
00:30:16,800 --> 00:30:17,520
Speaker 3: enjoyed that too.

604
00:30:17,760 --> 00:30:19,480
Speaker 1: That was a good one. I really enjoyed The Hearder

605
00:30:19,520 --> 00:30:21,880
Speaker 1: They Fall. My favorite movie from this year was shang Chi.

606
00:30:22,040 --> 00:30:22,920
Speaker 1: Did you watch shang Chi?

607
00:30:23,040 --> 00:30:24,560
Speaker 3: I haven't seen it yet. I started on a late

608
00:30:24,600 --> 00:30:25,880
Speaker 3: night and I said, girl, you know, you got to

609
00:30:25,880 --> 00:30:26,360
Speaker 3: go to bed.

610
00:30:26,600 --> 00:30:28,760
Speaker 1: I'm usually not the first person in line when a

611
00:30:28,800 --> 00:30:31,400
Speaker 1: Marvel movie comes out, and even with shang Chi, I

612
00:30:31,440 --> 00:30:33,640
Speaker 1: was just like, ah, you know, it's another Marvel thing.

613
00:30:33,720 --> 00:30:35,680
Speaker 1: But then you know, I was like, Okay, there's nothing

614
00:30:35,720 --> 00:30:38,200
Speaker 1: for me to watch, let me just see what it's about, because.

615
00:30:37,960 --> 00:30:39,680
Speaker 2: I'd heard really really great things.

616
00:30:39,840 --> 00:30:42,520
Speaker 1: And so the reason why I really like shang Chi

617
00:30:42,800 --> 00:30:47,600
Speaker 1: was because one we had Asian superhero, and two I

618
00:30:47,600 --> 00:30:51,360
Speaker 1: felt like they kind of disrupted the normal superhero plot

619
00:30:51,400 --> 00:30:55,360
Speaker 1: line where I really felt like the villain or the

620
00:30:55,440 --> 00:31:01,440
Speaker 1: bad guy in shang Chi was actually grief. So it

621
00:31:01,520 --> 00:31:04,959
Speaker 1: became like this really powerful story for me about losing

622
00:31:04,960 --> 00:31:08,360
Speaker 1: someone you love, the grief and how it manifests in

623
00:31:08,480 --> 00:31:12,520
Speaker 1: different people, and then how you conquer grief, and just

624
00:31:12,680 --> 00:31:15,480
Speaker 1: like the battles that people can be fighting internally.

625
00:31:15,360 --> 00:31:17,200
Speaker 2: And so I just thought it was phenomenal.

626
00:31:17,440 --> 00:31:20,480
Speaker 3: I'm trying to get all the love out. I don't

627
00:31:20,480 --> 00:31:21,920
Speaker 3: want to have any grief. I mean, I know I'm

628
00:31:21,920 --> 00:31:24,240
Speaker 3: gonna have it, and I try to pour out all

629
00:31:24,240 --> 00:31:27,360
Speaker 3: that love where I can and make it weird, you know, like,

630
00:31:27,920 --> 00:31:30,400
Speaker 3: I love you so much? Are you uncomfortable? I love

631
00:31:30,440 --> 00:31:31,040
Speaker 3: you even more?

632
00:31:31,440 --> 00:31:36,960
Speaker 2: You know? All right?

633
00:31:37,040 --> 00:31:43,680
Speaker 3: TT, you're the queen of TikTok and Instagram and Twitter.

634
00:31:43,720 --> 00:31:44,480
Speaker 3: Really I think.

635
00:31:44,320 --> 00:31:46,280
Speaker 2: You're on all of those, right, I'm on all of those.

636
00:31:46,320 --> 00:31:47,840
Speaker 2: I don't know if I'm the queen of it. Well,

637
00:31:47,880 --> 00:31:51,600
Speaker 2: you feel like the queen of it to me. I

638
00:31:51,640 --> 00:31:52,920
Speaker 2: want to know your favorite meme.

639
00:31:53,280 --> 00:31:56,480
Speaker 1: Okay, TikTok is one of the happiest places on earth

640
00:31:56,480 --> 00:32:00,000
Speaker 1: for me and one of the sounds that I truly

641
00:32:00,440 --> 00:32:01,560
Speaker 1: am always.

642
00:32:01,160 --> 00:32:02,960
Speaker 2: Going to scroll through.

643
00:32:03,000 --> 00:32:04,760
Speaker 1: So on the TikTok you can click on a sound

644
00:32:04,760 --> 00:32:06,560
Speaker 1: and you can see all the videos that were made

645
00:32:06,600 --> 00:32:08,680
Speaker 1: to that sound, and it's the one that goes.

646
00:32:08,680 --> 00:32:12,360
Speaker 5: Oh no, oh no, yes, oh no, no, no, no no,

647
00:32:13,520 --> 00:32:16,880
Speaker 5: and there's so many wild things happening, and I always

648
00:32:17,000 --> 00:32:20,040
Speaker 5: end up crying laughing.

649
00:32:20,360 --> 00:32:23,040
Speaker 1: Oh, it's amazing. That's my favorite. What about you, what's

650
00:32:23,040 --> 00:32:23,760
Speaker 1: your favorite meme?

651
00:32:24,080 --> 00:32:27,120
Speaker 3: I think I'm on the sound bandwagon with you. And

652
00:32:27,520 --> 00:32:30,800
Speaker 3: there's one where somebody is like, no, immediately, no, Like

653
00:32:30,840 --> 00:32:34,240
Speaker 3: it's like working all day and it's like all these

654
00:32:34,240 --> 00:32:36,320
Speaker 3: things like paying your bills this, and and people need

655
00:32:36,480 --> 00:32:38,520
Speaker 3: going through and looking at things and like, no, I'm

656
00:32:38,560 --> 00:32:43,440
Speaker 3: not gonna do that. No immediately, And I'm saying immediately

657
00:32:43,480 --> 00:32:47,560
Speaker 3: no to a lot of things. Don't bring your chaos

658
00:32:47,640 --> 00:32:49,080
Speaker 3: over here immediately.

659
00:32:49,160 --> 00:32:49,200
Speaker 2: No.

660
00:32:49,760 --> 00:32:52,160
Speaker 3: But really, we all are just memes. Do you remember

661
00:32:52,160 --> 00:32:54,720
Speaker 3: you made that meme of me when I was retelling

662
00:32:54,720 --> 00:32:57,440
Speaker 3: the story and I lay flat on the floor.

663
00:32:59,680 --> 00:33:02,680
Speaker 2: Is the snip is more? Yes? More?

664
00:33:03,160 --> 00:33:06,680
Speaker 1: That is definitely one of my favorite self made memes

665
00:33:06,680 --> 00:33:07,160
Speaker 1: of all time.

666
00:33:07,200 --> 00:33:08,720
Speaker 2: Maybe I'll post it. Yes.

667
00:33:09,120 --> 00:33:12,240
Speaker 3: If you or your friends have ever made memes of

668
00:33:12,280 --> 00:33:17,160
Speaker 3: each other, we want to see them. Tag us. What's

669
00:33:17,160 --> 00:33:20,040
Speaker 3: your favorite podcast aside from this one? I hope you're

670
00:33:20,080 --> 00:33:20,680
Speaker 3: enjoying this one.

671
00:33:20,680 --> 00:33:22,080
Speaker 2: Te T. I love Dope Labs.

672
00:33:22,120 --> 00:33:26,840
Speaker 1: It's my absolute favorite podcast. My favorite podcast is a

673
00:33:26,880 --> 00:33:28,800
Speaker 1: podcast as hosted by.

674
00:33:28,800 --> 00:33:29,720
Speaker 2: A friend of ours.

675
00:33:30,000 --> 00:33:33,120
Speaker 1: Her name is Ivy Lee Lee with one E, and

676
00:33:33,200 --> 00:33:36,760
Speaker 1: she has a podcast called Fear of Going Outside. Ivy

677
00:33:37,160 --> 00:33:39,800
Speaker 1: is a special woman in that I don't know if

678
00:33:39,840 --> 00:33:44,480
Speaker 1: I know someone funnier than Ivy. She has such good

679
00:33:44,560 --> 00:33:50,440
Speaker 1: comedic timing. She is not afraid of embarrassing herself, and

680
00:33:50,520 --> 00:33:53,240
Speaker 1: so the whole premise for Fear of Going Outside is

681
00:33:53,240 --> 00:33:57,080
Speaker 1: that Ivy is not an outdoorsy person, and so over

682
00:33:57,120 --> 00:34:01,240
Speaker 1: the course of a season, she goes camping, and so

683
00:34:01,480 --> 00:34:04,480
Speaker 1: she's getting all of the gears, she's preparing herself and

684
00:34:05,000 --> 00:34:07,800
Speaker 1: it is very funny. You have to listen to Fear

685
00:34:07,840 --> 00:34:10,719
Speaker 1: of Going Outside, hosted by Ivy Lee with one E,

686
00:34:10,880 --> 00:34:14,000
Speaker 1: and you can also follow her on Twitter and Instagram

687
00:34:14,040 --> 00:34:16,440
Speaker 1: at ivy Lea with one e and follow Fogo podcast.

688
00:34:16,800 --> 00:34:19,839
Speaker 3: I think my podcast pick and I've talked about this

689
00:34:19,880 --> 00:34:23,839
Speaker 3: one before. Okay, now listen Yeah from Netflicks, mm hmm.

690
00:34:24,120 --> 00:34:27,080
Speaker 3: I really enjoy their podcast. It's all about what's happening,

691
00:34:27,080 --> 00:34:29,640
Speaker 3: what's going on and their take on it and I

692
00:34:29,680 --> 00:34:32,680
Speaker 3: love it. They also just got a TV show, Yes Yes,

693
00:34:33,200 --> 00:34:36,200
Speaker 3: and we love Yesse.

694
00:34:36,440 --> 00:34:37,279
Speaker 2: You love to see it.

695
00:34:37,440 --> 00:34:40,560
Speaker 1: They are so fun to listen to and now will

696
00:34:40,600 --> 00:34:41,520
Speaker 1: be so fun to watch.

697
00:34:45,000 --> 00:34:46,920
Speaker 3: All Right, So we've gone through all of our other

698
00:34:46,960 --> 00:34:49,600
Speaker 3: favorite things, but I know you have a favorite science thing.

699
00:34:49,880 --> 00:34:52,240
Speaker 3: I want to know your favorite moment in your field.

700
00:34:52,440 --> 00:34:55,600
Speaker 1: The engineering thing that I felt like was fascinating is

701
00:34:55,600 --> 00:34:58,960
Speaker 1: something that should be I know is very interesting to

702
00:34:59,000 --> 00:35:02,480
Speaker 1: my friend because there is a lab group at the

703
00:35:02,560 --> 00:35:06,879
Speaker 1: University of Rochester and they have collaborators at Delft University

704
00:35:06,960 --> 00:35:09,880
Speaker 1: of Technology in the Netherlands, and they are three D

705
00:35:10,040 --> 00:35:11,680
Speaker 1: printing biofilms.

706
00:35:11,920 --> 00:35:16,560
Speaker 2: What, yes, they are three D printing biofilms.

707
00:35:16,760 --> 00:35:18,759
Speaker 3: What I did not know about that? Now you know,

708
00:35:19,120 --> 00:35:23,200
Speaker 3: I'm all about the biofilm. So biofilms are these communities

709
00:35:23,239 --> 00:35:26,280
Speaker 3: of bacteria. Sometimes you can have multiple species of bacteria.

710
00:35:26,360 --> 00:35:30,200
Speaker 3: Sometimes you know, people study just one species. But the

711
00:35:30,239 --> 00:35:34,560
Speaker 3: thing to know is biofilms are particularly resistant to different

712
00:35:34,760 --> 00:35:40,480
Speaker 3: disinfectants and antibiotics because they create this matrix, this extracellular matrix.

713
00:35:40,480 --> 00:35:45,080
Speaker 3: So outside the cell, a matrix of sugars, proteins, external DNA,

714
00:35:45,239 --> 00:35:48,000
Speaker 3: dead cells that are still trapped in there. So imagine

715
00:35:48,040 --> 00:35:51,040
Speaker 3: something that's like a conglomerate, and they have all these

716
00:35:51,080 --> 00:35:53,400
Speaker 3: proteins that are sometimes on the surface of cales. Some

717
00:35:53,440 --> 00:35:55,279
Speaker 3: of them come from what we call life cells or

718
00:35:55,320 --> 00:35:57,760
Speaker 3: cells that have burst, and so they protect the cells

719
00:35:57,760 --> 00:35:59,560
Speaker 3: that are living in there. You can imagine if you

720
00:35:59,560 --> 00:36:01,960
Speaker 3: have baccie you're trying to get rid of your antibiotic

721
00:36:02,040 --> 00:36:04,279
Speaker 3: can't really penetrate down in there, get in there and

722
00:36:04,360 --> 00:36:08,719
Speaker 3: kill the bacterio So you're saying they're three D printing biofilms. Now, yes,

723
00:36:08,800 --> 00:36:12,120
Speaker 3: they're three D printing E. Coli biofilms.

724
00:36:12,440 --> 00:36:14,920
Speaker 1: And so what they're hoping to do with this is

725
00:36:14,960 --> 00:36:19,160
Speaker 1: that it can help with understanding the behavior of bacterial

726
00:36:19,160 --> 00:36:23,279
Speaker 1: biofilms and help with the development of new engineered living

727
00:36:23,320 --> 00:36:26,759
Speaker 1: materials using synthetic biology and material science approaches.

728
00:36:26,960 --> 00:36:29,160
Speaker 3: Yes, that makes sense to me. Bilefilms sometimes take a

729
00:36:29,160 --> 00:36:32,440
Speaker 3: long time to accumulate, and sometimes the conditions we use

730
00:36:32,440 --> 00:36:34,680
Speaker 3: in the lab they're not conducive for creating biofilms. So

731
00:36:34,680 --> 00:36:36,439
Speaker 3: if I can just print them out over and over

732
00:36:36,520 --> 00:36:38,920
Speaker 3: again and then I can study them. You can't really

733
00:36:38,960 --> 00:36:41,600
Speaker 3: figure out how to combat or defeat something unless you

734
00:36:41,640 --> 00:36:44,120
Speaker 3: can reproduce that same thing over and over.

735
00:36:44,320 --> 00:36:47,680
Speaker 2: You know. Yeah, this is a really great advancement.

736
00:36:47,080 --> 00:36:49,000
Speaker 1: And it's really cool because they might be able to

737
00:36:49,280 --> 00:36:52,799
Speaker 1: use these biofilms for other applications as well. I think

738
00:36:52,800 --> 00:36:54,879
Speaker 1: I've read that they said that they can use it

739
00:36:54,920 --> 00:37:01,719
Speaker 1: for protective codings against pathogens on medical devices, for bioremedia, whatever.

740
00:37:02,000 --> 00:37:03,600
Speaker 3: They're using it to study those things.

741
00:37:03,840 --> 00:37:04,640
Speaker 2: That's really cool.

742
00:37:08,560 --> 00:37:12,040
Speaker 1: All right, So what has been your favorite science moment

743
00:37:12,200 --> 00:37:12,880
Speaker 1: in your field?

744
00:37:13,120 --> 00:37:14,160
Speaker 2: Have you heard of crisper?

745
00:37:14,400 --> 00:37:19,399
Speaker 3: Yeah, so that's clustered regularly interspaced short palindromic repeats. These

746
00:37:19,480 --> 00:37:23,960
Speaker 3: are DNA sequences and basically crisper technology is leveraging the

747
00:37:24,000 --> 00:37:28,240
Speaker 3: ability of enzymes to basically hone in on specific sequences

748
00:37:28,239 --> 00:37:31,920
Speaker 3: of DNA and then do gene editing in that specific area.

749
00:37:32,000 --> 00:37:34,919
Speaker 3: Chrisper technology is amazing. We've seen a lot of advances,

750
00:37:35,200 --> 00:37:37,920
Speaker 3: even a Nobel prize recently. But a lot of this

751
00:37:37,960 --> 00:37:40,319
Speaker 3: stuff when it comes to human application, we have been

752
00:37:40,360 --> 00:37:44,080
Speaker 3: seeing you know, in vitro or x vvo so alive

753
00:37:44,160 --> 00:37:47,200
Speaker 3: in living cells but maybe outside of the body. But

754
00:37:47,719 --> 00:37:51,480
Speaker 3: recently in twenty twenty one, we saw in vivo so

755
00:37:52,000 --> 00:37:55,440
Speaker 3: in the body, in the cell, in the organism crisper

756
00:37:55,800 --> 00:38:00,200
Speaker 3: gene editing. Why so, they are using crisper to actually

757
00:38:00,200 --> 00:38:03,200
Speaker 3: modify genes in the human body. And they use it

758
00:38:03,200 --> 00:38:07,440
Speaker 3: to target genes involved in inherited blindness. And so they

759
00:38:07,440 --> 00:38:10,239
Speaker 3: saw improve vision and two people. And they also used

760
00:38:10,239 --> 00:38:13,719
Speaker 3: it to limit the production of this like protein in

761
00:38:13,760 --> 00:38:14,840
Speaker 3: the liver that's toxic.

762
00:38:15,080 --> 00:38:17,799
Speaker 2: Oh my gosh.

763
00:38:17,080 --> 00:38:18,520
Speaker 3: I'm like, this is escalating.

764
00:38:18,600 --> 00:38:21,640
Speaker 1: Sounds likely some Star Trek stuff and I love it.

765
00:38:22,840 --> 00:38:25,600
Speaker 1: Go to the sick bay, Okay.

766
00:38:25,680 --> 00:38:27,839
Speaker 2: Go to the sick bay. They will treat you there.

767
00:38:27,880 --> 00:38:31,240
Speaker 2: Treat you there, and they're just gonna over your body

768
00:38:31,280 --> 00:38:34,520
Speaker 2: and you'll be all right. That is so cool.

769
00:38:34,920 --> 00:38:37,080
Speaker 3: And if you check out our show notes at Dope

770
00:38:37,160 --> 00:38:39,799
Speaker 3: lapspodcast dot com, we are going to link to these

771
00:38:39,960 --> 00:38:51,040
Speaker 3: articles so you can read more about this. This is

772
00:38:51,040 --> 00:38:53,800
Speaker 3: the last episode of twenty twenty one, so we'll be different.

773
00:38:53,840 --> 00:38:54,480
Speaker 2: When you hear from us.

774
00:38:54,560 --> 00:38:56,799
Speaker 3: Next time, it'll be twenty twenty two, New year knew

775
00:38:56,880 --> 00:38:59,640
Speaker 3: US probably.

776
00:39:00,000 --> 00:39:07,200
Speaker 1: Will probably be the same old US.

777
00:39:09,239 --> 00:39:12,600
Speaker 6: Dope Labs is a Spotify original production from Mega oh

778
00:39:12,719 --> 00:39:16,800
Speaker 6: Media Group. Producers are Jenny Rattlett Mast and Lydia Smith

779
00:39:16,880 --> 00:39:21,440
Speaker 6: of Way Runner Studios. Editing and sound designed by Rob Smerciak,

780
00:39:22,160 --> 00:39:26,400
Speaker 6: Mixing by Hannis Brown. Original music composed and produced by

781
00:39:26,440 --> 00:39:31,920
Speaker 6: Taka Yasuzawa and Alex Sugira from Spotify. Executive producer Gina

782
00:39:31,960 --> 00:39:36,239
Speaker 6: Delvack and creative producers Baron Farmer and Candice Manriquez Rin

783
00:39:37,040 --> 00:39:42,080
Speaker 6: Special thanks to Shirley Ramos, yasmin A, Fifi Kamola, Till Krake,

784
00:39:42,440 --> 00:39:46,440
Speaker 6: and Brian Marquis. Executive producers from Mega Oh Media Group

785
00:39:46,719 --> 00:39:50,720
Speaker 6: are My Internet Bessies, t T. Shodia and Zakiyah Watli.

786
00:40:00,080 --> 00:40:01,600
Speaker 6: M hmmmmmmmm.

787
00:40:03,680 --> 00:40:04,200
Speaker 2: Broncus.

788
00:40:04,440 --> 00:40:10,040
Speaker 3: I like that word that might not be right, because

789
00:40:10,040 --> 00:40:11,360
Speaker 3: I just right here saying stuff.

790
00:40:11,400 --> 00:40:14,920
Speaker 2: My friend said it, so it's right. Broncosaurus, Broncosaurus Rex