1 00:00:01,440 --> 00:00:04,600 Speaker 1: Welcome to you stuff. You should know front House stuff 2 00:00:04,600 --> 00:00:13,000 Speaker 1: where its dot com. Hey you, and welcome to the podcast. 3 00:00:13,039 --> 00:00:15,920 Speaker 1: And Josh Clark, I almost just forgot what I was 4 00:00:15,960 --> 00:00:20,200 Speaker 1: gonna say your name. Yeah. Uh, there's Charles w. Chok 5 00:00:20,280 --> 00:00:26,040 Speaker 1: Pribb piping in, and there's the trio. Yeah, the trifecta 6 00:00:26,640 --> 00:00:31,480 Speaker 1: and it's terrible Ikea lamp. Uh do you think, well 7 00:00:31,520 --> 00:00:33,199 Speaker 1: we are getting a little heat off of it right now? 8 00:00:33,280 --> 00:00:35,640 Speaker 1: It's a nice Did you ever see that Ikea commercial 9 00:00:35,680 --> 00:00:37,640 Speaker 1: about the lamp that was thrown out on the street. No, 10 00:00:37,960 --> 00:00:40,320 Speaker 1: it was really good. Well what happened to it? Was 11 00:00:40,320 --> 00:00:42,519 Speaker 1: it like the monkey at the Ikea? No, it was 12 00:00:42,720 --> 00:00:45,519 Speaker 1: like a lamp gets thrown out with the like someone's 13 00:00:45,560 --> 00:00:48,080 Speaker 1: just redoing parts of their apartment and the lamp is 14 00:00:49,560 --> 00:00:52,040 Speaker 1: kicked to the curve as a computer animated. So it's 15 00:00:52,159 --> 00:00:56,720 Speaker 1: it's a human formed not human forms? What am I saying? Anthropogenic? 16 00:00:57,280 --> 00:00:59,920 Speaker 1: Anthropomorphized and like looks up at the apartment that he 17 00:01:00,080 --> 00:01:01,680 Speaker 1: is just thrown out of it and stuff like that. 18 00:01:02,120 --> 00:01:04,240 Speaker 1: Does he go back to Sweden? I don't. I don't 19 00:01:04,240 --> 00:01:07,959 Speaker 1: remember how it ends. Just remember the lamp like turns 20 00:01:07,959 --> 00:01:10,520 Speaker 1: out human. It was sad. It was like sad. Okay, 21 00:01:10,520 --> 00:01:13,080 Speaker 1: I got teared up. Did you go buy one of 22 00:01:13,080 --> 00:01:17,920 Speaker 1: those lamps? No, it didn't work. Um, so, I guess 23 00:01:17,920 --> 00:01:20,400 Speaker 1: you're feeling pretty good since we're talking about lamps and everything, 24 00:01:21,200 --> 00:01:23,600 Speaker 1: and lamps I do. That means it's a good days. 25 00:01:23,640 --> 00:01:27,360 Speaker 1: A clear signal checks in a good mood everybody. Uh. 26 00:01:27,720 --> 00:01:29,200 Speaker 1: You know. One of the reasons why you're in a 27 00:01:29,240 --> 00:01:37,919 Speaker 1: good mood because your guts are functioning properly. Yeah, ish, yeah, 28 00:01:38,120 --> 00:01:41,800 Speaker 1: you know me, it's day to day. Yeah, with my stomach. Well, 29 00:01:42,200 --> 00:01:47,000 Speaker 1: that's exactly right. Things change very quickly because of your stomach, 30 00:01:47,040 --> 00:01:48,800 Speaker 1: and your stomach can't affect your mood. As a matter 31 00:01:48,800 --> 00:01:51,480 Speaker 1: of fact, the vast majority of the serotonin, which is 32 00:01:51,480 --> 00:01:56,400 Speaker 1: a mood stabilizing neurotransmitter, is produced in your gut. Yeah. 33 00:01:56,560 --> 00:01:59,280 Speaker 1: And the way that things like serotonin and other stuff 34 00:02:00,080 --> 00:02:05,480 Speaker 1: uh is produced is thanks to our microbiome. Dude, Yeah, 35 00:02:06,240 --> 00:02:09,520 Speaker 1: our microbiome. This is the most fascinating thing going on 36 00:02:09,600 --> 00:02:13,080 Speaker 1: in medicine science right now. Yeah. I get the impression 37 00:02:13,080 --> 00:02:16,519 Speaker 1: reading various articles. When scientists talk about it, they all 38 00:02:16,520 --> 00:02:20,000 Speaker 1: seem really pumped up. It's like the breakthrough of the 39 00:02:20,639 --> 00:02:24,120 Speaker 1: century and this thing like just started it's two and 40 00:02:24,200 --> 00:02:27,720 Speaker 1: like this could remain the breakthrough of the century. Yeah. 41 00:02:27,760 --> 00:02:30,280 Speaker 1: And I mean if you think about the timeline up 42 00:02:30,320 --> 00:02:33,239 Speaker 1: until the twentieth century, you were like a plant or 43 00:02:33,240 --> 00:02:36,480 Speaker 1: an animal, right, And then it was literally like the 44 00:02:36,520 --> 00:02:39,959 Speaker 1: nineteen fifties and sixties that they started saying, maybe we 45 00:02:40,000 --> 00:02:42,919 Speaker 1: should break things down a little further, and they came 46 00:02:43,000 --> 00:02:45,520 Speaker 1: up with the five kingdoms. And I think they're now 47 00:02:45,560 --> 00:02:48,600 Speaker 1: even as a six kingdom. Well, there's three domains, now 48 00:02:49,240 --> 00:02:54,280 Speaker 1: eight kingdoms, there's eight and three two of the domains 49 00:02:54,360 --> 00:02:57,160 Speaker 1: are account for two of the kingdoms as well. Bacteria 50 00:02:57,240 --> 00:03:00,680 Speaker 1: and archia and archia used to be thought that they 51 00:03:00,720 --> 00:03:04,720 Speaker 1: were the same as bacteria. Yes, then they started looking 52 00:03:04,720 --> 00:03:06,280 Speaker 1: into them a little more and they're like, oh, these 53 00:03:06,320 --> 00:03:09,079 Speaker 1: guys are made up of different amino acids and they 54 00:03:09,080 --> 00:03:12,639 Speaker 1: have different characteristics. And our chia, for example, are the 55 00:03:12,800 --> 00:03:17,840 Speaker 1: kind of microbial life that you'll only find around undersea 56 00:03:18,440 --> 00:03:23,720 Speaker 1: hot water sulfur vents like volcanos, not not in your 57 00:03:23,760 --> 00:03:28,560 Speaker 1: vagina or in your mouth. Well, no, because they're extreme 58 00:03:28,600 --> 00:03:31,520 Speaker 1: aphiles and a vagina or a mouth isn't that extreme? 59 00:03:31,960 --> 00:03:34,320 Speaker 1: Well it is because our kia lives there, that's right. 60 00:03:34,400 --> 00:03:36,720 Speaker 1: So the fact that we figured out that ar chia 61 00:03:36,840 --> 00:03:40,840 Speaker 1: are different than bacteria, and not only that they don't 62 00:03:40,960 --> 00:03:45,200 Speaker 1: just live in extreme environments, but also on the human body. 63 00:03:45,600 --> 00:03:50,240 Speaker 1: That was something we can thank the Human Microbiome Project for. Yeah, 64 00:03:50,240 --> 00:03:52,960 Speaker 1: and that wasn't I think they didn't even discover our 65 00:03:53,040 --> 00:03:55,840 Speaker 1: key until the nineteen seventies. So this all this stuff 66 00:03:55,920 --> 00:03:59,400 Speaker 1: is brand new and exciting. And by the way, the 67 00:03:59,400 --> 00:04:04,200 Speaker 1: three domain are bacteria, or chea and eukaryotes for us 68 00:04:04,360 --> 00:04:10,480 Speaker 1: or eukaryotes because we have nucleus as nuclei. Yeah, let's 69 00:04:10,480 --> 00:04:12,840 Speaker 1: talk about this man we we have before. I'm sure 70 00:04:12,920 --> 00:04:17,120 Speaker 1: you remember in the fecal transplant episode, because it definitely 71 00:04:17,160 --> 00:04:21,000 Speaker 1: factors into it. You can, um, Yeah, you can cure 72 00:04:21,680 --> 00:04:25,080 Speaker 1: claus Stradium difficile, which is something where that it's a 73 00:04:25,160 --> 00:04:31,080 Speaker 1: gut microbe. It's very harmful to humans that can colonize 74 00:04:31,080 --> 00:04:35,000 Speaker 1: your guts after you take antibiotics, which is basically just 75 00:04:35,040 --> 00:04:38,919 Speaker 1: like a slash and burn approach, which again thanks to 76 00:04:38,960 --> 00:04:43,599 Speaker 1: the Human Microbiome Project. Um, we're starting to understand we 77 00:04:43,680 --> 00:04:47,000 Speaker 1: might want to use antibiotics because what we used to 78 00:04:47,040 --> 00:04:50,440 Speaker 1: just think of is almost entirely bad are actually mostly 79 00:04:50,480 --> 00:04:54,680 Speaker 1: beneficial and even some of the bad bacteria a k a. 80 00:04:54,839 --> 00:04:59,679 Speaker 1: Germs um are actually present in our microbiome and normally 81 00:04:59,720 --> 00:05:03,000 Speaker 1: living harmony. It just appears that when the microbiome gets 82 00:05:03,000 --> 00:05:05,840 Speaker 1: out of whack, that's when disease happens. Yeah, Like you 83 00:05:05,880 --> 00:05:08,400 Speaker 1: may have E. Coli in your body right now. Yeah, 84 00:05:08,440 --> 00:05:11,159 Speaker 1: I probably do, but it's not a big deal. If 85 00:05:11,240 --> 00:05:17,359 Speaker 1: you're always talk about stasis, keeping things balanced in life 86 00:05:17,600 --> 00:05:20,279 Speaker 1: is the key. And uh, it's definitely the key with 87 00:05:20,320 --> 00:05:26,520 Speaker 1: your own personal microbiome, which we have learned is very individualized, 88 00:05:26,920 --> 00:05:29,560 Speaker 1: which we'll get to with the project. Right, So, if 89 00:05:29,600 --> 00:05:33,720 Speaker 1: you take a human body and you scanned all the 90 00:05:33,800 --> 00:05:37,760 Speaker 1: genes in it, well, you would find is there are 91 00:05:37,839 --> 00:05:44,240 Speaker 1: about a hundred times more microbial genes than human genes 92 00:05:45,000 --> 00:05:48,440 Speaker 1: in a genetic scan of a human body. Yeah, are 93 00:05:48,480 --> 00:05:51,359 Speaker 1: are Human cells only make up about ten percent of 94 00:05:51,360 --> 00:05:54,719 Speaker 1: the cells in the body. And here's another great stat 95 00:05:55,360 --> 00:06:00,000 Speaker 1: We actually the healthiest person on the planet as between 96 00:06:00,160 --> 00:06:04,160 Speaker 1: two and five pounds of bacteria pounds. Yeah, of your 97 00:06:04,200 --> 00:06:09,080 Speaker 1: body weight, about up to five pounds. Yes. What's crazy 98 00:06:09,200 --> 00:06:15,320 Speaker 1: is is that that's even considering that microbial cells are 99 00:06:15,360 --> 00:06:18,520 Speaker 1: anywhere from a tenth to a hundredth the size of 100 00:06:18,560 --> 00:06:20,839 Speaker 1: an average human cell. Yes, you do, you know how many? 101 00:06:20,960 --> 00:06:24,440 Speaker 1: How much five pounds would have to quite a few. 102 00:06:24,960 --> 00:06:27,480 Speaker 1: As a matter of fact, there's um an estimated hundred 103 00:06:27,520 --> 00:06:33,680 Speaker 1: trillion microbes on an average human person, just in on 104 00:06:34,600 --> 00:06:38,240 Speaker 1: and a part of such a such a part of 105 00:06:38,520 --> 00:06:42,040 Speaker 1: us and our our normal functioning that we're finding very 106 00:06:42,080 --> 00:06:46,680 Speaker 1: quickly that they're they're pretty much interchangeable. There, they are 107 00:06:46,839 --> 00:06:50,080 Speaker 1: one with us and UM as their host. We are 108 00:06:50,160 --> 00:06:52,560 Speaker 1: kind of one with them, like you have fungus on 109 00:06:52,600 --> 00:06:55,640 Speaker 1: your skin. Yeah, no big deal. Right. Well, that's another 110 00:06:55,680 --> 00:06:58,680 Speaker 1: thing too we should talk about. When people say microbe UM, 111 00:06:58,760 --> 00:07:03,599 Speaker 1: it's kind of a catch all word for yeah, any tiny, 112 00:07:03,640 --> 00:07:07,680 Speaker 1: typically unicellular life. And that's the case here too. But 113 00:07:07,760 --> 00:07:11,920 Speaker 1: it doesn't just mean bacteria. The human microbiome is made 114 00:07:12,000 --> 00:07:14,560 Speaker 1: up of lots of bacteria and lots of lots of 115 00:07:14,560 --> 00:07:18,680 Speaker 1: different types of bacteria um. For example, the mouth may 116 00:07:18,680 --> 00:07:23,480 Speaker 1: have up to five thousand different species of bacteria. Yeah, 117 00:07:23,520 --> 00:07:26,560 Speaker 1: and they're not just lazing around in your body like 118 00:07:26,640 --> 00:07:31,760 Speaker 1: they are responsible for keeping your body in check or 119 00:07:31,880 --> 00:07:34,040 Speaker 1: you know, sometimes responsible for it being out of whack. 120 00:07:34,560 --> 00:07:37,440 Speaker 1: But they're all they're all doing something or laying there 121 00:07:37,520 --> 00:07:41,560 Speaker 1: waiting to do something. You also have a what's called 122 00:07:41,560 --> 00:07:45,760 Speaker 1: a virume. You have viruses in your microbiome, and they 123 00:07:45,800 --> 00:07:51,680 Speaker 1: appear to be present to keep the bacteria populations from 124 00:07:51,720 --> 00:07:54,480 Speaker 1: getting out of control. Like they're there to infect bacteria 125 00:07:55,000 --> 00:07:58,160 Speaker 1: to kill them off. And they it's kind of like, um, 126 00:07:58,200 --> 00:08:03,080 Speaker 1: they're the lions to the gazelle of the microbiome. Okay, 127 00:08:03,320 --> 00:08:06,320 Speaker 1: you take away the lions. You've got too many gazelles. Yeah, 128 00:08:06,560 --> 00:08:09,280 Speaker 1: they all start to starve, they don't function correctly. They 129 00:08:09,320 --> 00:08:11,320 Speaker 1: may even eat each other. You don't want to see 130 00:08:11,320 --> 00:08:14,600 Speaker 1: a gazelle eat another gazelle. So you have lions there, 131 00:08:14,600 --> 00:08:18,760 Speaker 1: and the lions, these apex predators keep the gazelle population 132 00:08:18,800 --> 00:08:23,080 Speaker 1: and check and ultimately healthy. Paradoxically, the same thing with 133 00:08:23,120 --> 00:08:25,680 Speaker 1: the virum in your microbiome. Yeah, I mean they we 134 00:08:25,760 --> 00:08:29,240 Speaker 1: know they aid like gut bacteria aids digestion, and we'll 135 00:08:29,240 --> 00:08:31,760 Speaker 1: get the gut bacteria more. I mean, they're discovering just 136 00:08:32,040 --> 00:08:36,800 Speaker 1: all kinds of things that affects uh, synthesized vitamins. Um. 137 00:08:36,840 --> 00:08:39,760 Speaker 1: When you poop in the toilet and you look at 138 00:08:39,760 --> 00:08:42,640 Speaker 1: your poop, which you should do, by the way, like 139 00:08:42,760 --> 00:08:46,400 Speaker 1: you know, on a regular basis um, how much is it? 140 00:08:46,440 --> 00:08:49,760 Speaker 1: Is it half? From a third to half, so a 141 00:08:49,840 --> 00:08:53,920 Speaker 1: third to half of that is microbial biomass. It's not food. No, 142 00:08:54,080 --> 00:08:57,720 Speaker 1: it's like dead and living bacteria that you're pooping out 143 00:08:58,160 --> 00:09:01,520 Speaker 1: about half half. I saw something that was kind of 144 00:09:01,520 --> 00:09:06,360 Speaker 1: mind blowing to um. It's it's really neat and accurate, 145 00:09:06,520 --> 00:09:10,560 Speaker 1: especially on a microbial level. To imagine your alimentary system, 146 00:09:10,559 --> 00:09:15,280 Speaker 1: your digestive system, as the inside of that is technically 147 00:09:15,480 --> 00:09:19,440 Speaker 1: outside of your body. You have a hole, a trail 148 00:09:19,760 --> 00:09:24,840 Speaker 1: running through the middle of your body. That's that's technically 149 00:09:24,840 --> 00:09:28,679 Speaker 1: the outside. Uh yeah, I guess I see what you mean. 150 00:09:29,160 --> 00:09:31,520 Speaker 1: It's just chew on it for a minute, like the 151 00:09:31,520 --> 00:09:35,119 Speaker 1: the inside of your digestive system is technically the outside 152 00:09:35,160 --> 00:09:41,360 Speaker 1: of your body, Like that's outside of your body. Yeah, 153 00:09:41,400 --> 00:09:44,520 Speaker 1: it's confusing, it is. But once once your head wraps 154 00:09:44,559 --> 00:09:46,760 Speaker 1: around it, it's like one hand clapping kind of thing 155 00:09:47,320 --> 00:09:51,960 Speaker 1: and you're just like, whoa, that is neat. Uh all right, 156 00:09:52,040 --> 00:09:55,080 Speaker 1: So that's I guess the briefest of overviews of microbes 157 00:09:55,800 --> 00:09:58,480 Speaker 1: and bacteria, which we've talked about ad nauseum on the 158 00:09:58,480 --> 00:10:02,120 Speaker 1: show and our Great Suggestion podcast. That was one of 159 00:10:02,120 --> 00:10:04,800 Speaker 1: my favorite ones and then we've already talked about the 160 00:10:04,800 --> 00:10:09,840 Speaker 1: poop shakes. Uh. So the National Institutes of Health came 161 00:10:09,880 --> 00:10:12,800 Speaker 1: up with a plan, got some money together, and said, 162 00:10:13,400 --> 00:10:15,800 Speaker 1: let's try and do what the Human Genome Project did. 163 00:10:15,880 --> 00:10:20,240 Speaker 1: Let's try and map out the micro the human microbiome, 164 00:10:20,760 --> 00:10:27,079 Speaker 1: which is a very tough task because everyone is different. Yeah. Well, yeah, 165 00:10:27,200 --> 00:10:31,040 Speaker 1: everyone's microbiome is different. And I just saw today it 166 00:10:31,120 --> 00:10:33,679 Speaker 1: was released from the University of Michigan. They've kind of 167 00:10:33,720 --> 00:10:37,720 Speaker 1: already determined there is no such thing as a baseline 168 00:10:37,760 --> 00:10:41,400 Speaker 1: healthy microbiome. Yeah, and that was one of the goals 169 00:10:41,440 --> 00:10:43,840 Speaker 1: of this project that was started in two thousand and seven, 170 00:10:43,920 --> 00:10:49,240 Speaker 1: was that um to to establish a baseline micro biome, 171 00:10:49,559 --> 00:10:52,600 Speaker 1: Like they didn't know what one looked like like. They 172 00:10:52,679 --> 00:10:55,760 Speaker 1: knew that people had tons of bacteria and protozoa and 173 00:10:55,880 --> 00:10:59,000 Speaker 1: viruses all over us and in us, but what is 174 00:10:59,000 --> 00:11:01,800 Speaker 1: that supposed to look like? And when you figure out 175 00:11:01,800 --> 00:11:03,840 Speaker 1: what it's supposed to look like, then you can figure 176 00:11:03,840 --> 00:11:08,000 Speaker 1: out what what an unhealthy one looks like and then 177 00:11:08,040 --> 00:11:11,760 Speaker 1: possibly how to correct that by adjusting this this microbial 178 00:11:11,840 --> 00:11:15,839 Speaker 1: ecosystem back to a baseline. But I'm not surprised that 179 00:11:15,880 --> 00:11:18,720 Speaker 1: they found that there isn't a baseline that is two different, 180 00:11:19,000 --> 00:11:21,120 Speaker 1: and that doesn't mean that they can't like learn a 181 00:11:21,120 --> 00:11:23,400 Speaker 1: lot and help us out a lot. What they're basically 182 00:11:23,440 --> 00:11:27,079 Speaker 1: saying is you take a dozen completely healthy people and 183 00:11:27,120 --> 00:11:30,640 Speaker 1: their microbimes are gonna be completely different. Still, and there 184 00:11:30,720 --> 00:11:37,360 Speaker 1: was UM. There's one huge revolution in UM in the 185 00:11:37,480 --> 00:11:42,319 Speaker 1: study of bacterial or microbial life that that made this 186 00:11:42,440 --> 00:11:46,679 Speaker 1: project possible. Same with the human genome, but UM much 187 00:11:46,720 --> 00:11:50,720 Speaker 1: more for this it's called metagenomics. And prior to the 188 00:11:50,760 --> 00:11:55,080 Speaker 1: event and metagenomics, if you wanted to study bacteria, you 189 00:11:55,160 --> 00:12:00,800 Speaker 1: had to find a bacteria that could be replicated cloned, yeah, 190 00:12:00,840 --> 00:12:05,600 Speaker 1: in the laboratory setting, and UM disaccounted for just a 191 00:12:05,720 --> 00:12:09,680 Speaker 1: very very small fraction of the number of microbes out there. 192 00:12:10,240 --> 00:12:13,400 Speaker 1: What's more so, not only did you not have a 193 00:12:13,400 --> 00:12:18,640 Speaker 1: representative sample, but you also didn't have UM any kind 194 00:12:18,679 --> 00:12:22,600 Speaker 1: of anything less than an artificial setting. So even if 195 00:12:22,640 --> 00:12:25,840 Speaker 1: you did get these microbes, if you could replicate them 196 00:12:25,880 --> 00:12:29,079 Speaker 1: in the lab, UM, they weren't gonna behave the way 197 00:12:29,120 --> 00:12:31,680 Speaker 1: they would in their natural setting, like on your body. 198 00:12:32,040 --> 00:12:36,040 Speaker 1: So what metagenomics did UM was you can now take 199 00:12:36,120 --> 00:12:39,320 Speaker 1: like a representative sample, say like a clump of soil 200 00:12:40,000 --> 00:12:44,240 Speaker 1: or a swab of somebody's earful and get all of 201 00:12:44,280 --> 00:12:48,000 Speaker 1: the microbe microbes in there, and then basically just do 202 00:12:48,080 --> 00:12:51,680 Speaker 1: this rough scan of them, separate all the DNA out 203 00:12:52,440 --> 00:12:56,920 Speaker 1: at these enzymes that go and clip coherent fragments of 204 00:12:56,960 --> 00:12:58,880 Speaker 1: this DNA out, and then you take it and you 205 00:12:58,920 --> 00:13:01,960 Speaker 1: put it into what's all the model organism, and that 206 00:13:02,040 --> 00:13:05,960 Speaker 1: model organism starts to replicate as cells, and then each 207 00:13:06,000 --> 00:13:10,280 Speaker 1: cell displays a certain characteristic associated with a different microbe. 208 00:13:10,520 --> 00:13:12,760 Speaker 1: So all of a sudden you can start studying the 209 00:13:12,760 --> 00:13:16,040 Speaker 1: different cells and say, oh, well, this has to do 210 00:13:16,160 --> 00:13:20,240 Speaker 1: with this microbe, and this means that this protozoa is present, 211 00:13:20,280 --> 00:13:22,680 Speaker 1: and so on and so forth, and now you can 212 00:13:22,720 --> 00:13:27,640 Speaker 1: get a truly representative sample of what's in a microbiome. 213 00:13:27,920 --> 00:13:30,920 Speaker 1: And without metagenomics like this, none of this would be possible. 214 00:13:31,320 --> 00:13:33,920 Speaker 1: But now we're starting to find all sorts of new 215 00:13:34,480 --> 00:13:37,640 Speaker 1: uh not just information, but even new species of bacteria 216 00:13:37,679 --> 00:13:41,199 Speaker 1: and protozoa. And fun, guy, from the study of this stuff, 217 00:13:41,920 --> 00:13:44,079 Speaker 1: which is a great thing. It is a great thing, 218 00:13:44,240 --> 00:13:46,200 Speaker 1: and we'll explain why it's a great thing right after 219 00:13:46,240 --> 00:13:59,120 Speaker 1: this break. Hey, Chuck, Hey, you know me I'm a 220 00:13:59,160 --> 00:14:02,360 Speaker 1: snack guy. I love snacks. You do. I also love 221 00:14:02,520 --> 00:14:05,440 Speaker 1: convenient snacks. Well, I've got some news for you, then, 222 00:14:05,480 --> 00:14:08,760 Speaker 1: my friends, what nature Box? Oh? Yes, I love nature Box. 223 00:14:08,840 --> 00:14:12,240 Speaker 1: You want convenient snacks. We're talking healthy and great tasting snacks. 224 00:14:12,280 --> 00:14:14,760 Speaker 1: Like have you ever had the P V and J granola? Oh? Yeah, 225 00:14:14,760 --> 00:14:17,880 Speaker 1: that's good stuff. I also love the salted caramel pretzel pops, 226 00:14:17,960 --> 00:14:21,800 Speaker 1: which are awesome. They're like basically four different great things 227 00:14:21,840 --> 00:14:24,920 Speaker 1: all mixed together, and I have to have men. I'm 228 00:14:24,960 --> 00:14:28,680 Speaker 1: addicted to the Serata roasted cashews. Well, the great thing 229 00:14:28,720 --> 00:14:31,760 Speaker 1: about all that is there are zero transpats, zero high 230 00:14:31,800 --> 00:14:34,680 Speaker 1: fruit toset, corn syrup, and nothing artificial. My friend, that's right. 231 00:14:34,720 --> 00:14:37,800 Speaker 1: There's also snacks that are gluten conscious and non GMO 232 00:14:38,400 --> 00:14:41,240 Speaker 1: plus chuck. Like we said, it's convenient. You can get 233 00:14:41,320 --> 00:14:43,960 Speaker 1: nature Box shipped right to your door by heading over 234 00:14:44,000 --> 00:14:46,320 Speaker 1: to nature box dot com. Yeah, and it's free shipping 235 00:14:46,520 --> 00:14:48,880 Speaker 1: anywhere in the US. Baby, that's right. So we have 236 00:14:48,920 --> 00:14:51,200 Speaker 1: a special deal. As if that wasn't good enough, you 237 00:14:51,240 --> 00:14:53,360 Speaker 1: can try nature box right now and get fifty off 238 00:14:53,400 --> 00:14:55,760 Speaker 1: your first box by going to nature box dot com 239 00:14:55,880 --> 00:15:00,280 Speaker 1: slash stuff. That's nature Box dot com slash stu f 240 00:15:00,440 --> 00:15:03,400 Speaker 1: F Stay full, stay strong, go to nature box dot 241 00:15:03,440 --> 00:15:08,560 Speaker 1: com slash stuff. That's nature box dot com slash stuff. Okay, 242 00:15:08,600 --> 00:15:10,480 Speaker 1: we're back, all right. So now I guess we can 243 00:15:10,480 --> 00:15:13,360 Speaker 1: talk about some of these great findings, some of the 244 00:15:13,400 --> 00:15:17,760 Speaker 1: newest findings in the last what yours it? Well, they 245 00:15:17,800 --> 00:15:20,560 Speaker 1: started in two seven seven years old, and it seems 246 00:15:20,640 --> 00:15:23,960 Speaker 1: like the first crop of like amazing stuff started in 247 00:15:24,000 --> 00:15:27,560 Speaker 1: about two twelve, so after they had categorized things and 248 00:15:27,600 --> 00:15:30,000 Speaker 1: got like throwing all the crawfish out on the table, 249 00:15:30,240 --> 00:15:32,520 Speaker 1: right in the corn. Yeah, a little corn is good. 250 00:15:32,680 --> 00:15:36,440 Speaker 1: Have you ever done that? I've had that before. Yeah, 251 00:15:36,480 --> 00:15:39,320 Speaker 1: it's good stuff. It's fun. Go to a big party. 252 00:15:39,800 --> 00:15:44,960 Speaker 1: There's a place in um on Beuford Highway called, um 253 00:15:45,080 --> 00:15:47,480 Speaker 1: the Crawfish Shack. I've heard of that, but I haven't been. 254 00:15:48,040 --> 00:15:49,440 Speaker 1: Did they do it like that? Did they just dump 255 00:15:49,480 --> 00:15:51,480 Speaker 1: it on the table and it's all picnic tables? No, 256 00:15:51,600 --> 00:15:53,720 Speaker 1: it's in the bowls and stuff like that, but um, 257 00:15:53,760 --> 00:15:57,920 Speaker 1: but it's all picnic tables inside and um just huge 258 00:15:58,000 --> 00:16:01,440 Speaker 1: rolls of paper towels and it's that place is so good. Yeah, 259 00:16:01,440 --> 00:16:03,120 Speaker 1: I guess you can't do that as a restaurant. But 260 00:16:03,160 --> 00:16:05,840 Speaker 1: if you go to a true crawfish boil at someone's home, 261 00:16:06,360 --> 00:16:09,320 Speaker 1: you have the picnic table covered with the plastic thing 262 00:16:09,400 --> 00:16:11,880 Speaker 1: and you just dump it on the table and everyone 263 00:16:12,000 --> 00:16:14,760 Speaker 1: stands around like a bunch of animals, right, getting drunk 264 00:16:14,800 --> 00:16:18,760 Speaker 1: and eating, like sucking the heads of crawfish. But my 265 00:16:18,760 --> 00:16:20,840 Speaker 1: my family used to do something similar to that when 266 00:16:20,880 --> 00:16:24,160 Speaker 1: I was little in Toledo. We would eat um my 267 00:16:24,240 --> 00:16:27,640 Speaker 1: dad call it garbage pail stew. Are you familiar? Is 268 00:16:27,680 --> 00:16:30,320 Speaker 1: it like all the leftovers? No, it's like you use 269 00:16:30,360 --> 00:16:33,240 Speaker 1: a trash can to make it. Oh, I never heard 270 00:16:33,240 --> 00:16:36,520 Speaker 1: of it over like a flame, and obviously use a 271 00:16:36,520 --> 00:16:38,960 Speaker 1: new trash can, like a brand new one. So I 272 00:16:39,000 --> 00:16:41,520 Speaker 1: guess when dad got a new trash can, we would 273 00:16:41,560 --> 00:16:45,040 Speaker 1: have garbage pails stew. Anyway, the metal trash can it was, yes, 274 00:16:45,320 --> 00:16:49,320 Speaker 1: it was more like a the plastic just just trying 275 00:16:49,360 --> 00:16:53,680 Speaker 1: to like a one of the old timing ones. What 276 00:16:53,760 --> 00:16:55,320 Speaker 1: kind of flame you got in your house? And I 277 00:16:55,320 --> 00:16:57,880 Speaker 1: don't remember what it cooked it on? I don't like 278 00:16:57,960 --> 00:17:00,880 Speaker 1: in my in my mind's eye, I can't look down. 279 00:17:01,240 --> 00:17:03,240 Speaker 1: I can just see you can just see the kind 280 00:17:03,240 --> 00:17:05,320 Speaker 1: of the top of it. But anyway, it was like 281 00:17:05,359 --> 00:17:08,439 Speaker 1: a Yankee northern Midwestern version of it. So there's like 282 00:17:08,480 --> 00:17:11,320 Speaker 1: lots of cabbage in it and and like kill Bossa 283 00:17:11,400 --> 00:17:13,640 Speaker 1: and stuff like that, but it was essentially the same 284 00:17:13,680 --> 00:17:17,040 Speaker 1: thing and you would eat it on like like newspaper. 285 00:17:17,320 --> 00:17:19,080 Speaker 1: I can't wait to get emails from people who are like, 286 00:17:19,200 --> 00:17:21,440 Speaker 1: we did that same thing. I've looked around, I've never 287 00:17:21,480 --> 00:17:24,280 Speaker 1: seen it since. I'm sure that, Yeah, that sounds like 288 00:17:24,320 --> 00:17:26,920 Speaker 1: a thing that or your dad is very unique person, 289 00:17:27,880 --> 00:17:30,400 Speaker 1: is the way to put it, all, right, So back 290 00:17:30,400 --> 00:17:34,919 Speaker 1: to the project and the findings. Um, one of the 291 00:17:34,960 --> 00:17:39,880 Speaker 1: things they've learned is that periodontist this is gum disease. 292 00:17:40,640 --> 00:17:45,240 Speaker 1: Some bacteria are elevated if you have periodontists. So that's 293 00:17:45,240 --> 00:17:47,600 Speaker 1: gonna give you a little insight to maybe how you 294 00:17:47,600 --> 00:17:49,920 Speaker 1: can better take care of your mouth. What kind of 295 00:17:49,920 --> 00:17:53,160 Speaker 1: bacteria you need in there, what kind of you don't, Yeah, exactly, 296 00:17:53,280 --> 00:17:56,880 Speaker 1: And like for example, Strip, the caucus mutans is responsible 297 00:17:56,920 --> 00:18:01,320 Speaker 1: for cavities. Um, so you wanna take care of your 298 00:18:01,359 --> 00:18:04,040 Speaker 1: strep to caucus mu cans mue Can's. The thing is 299 00:18:04,240 --> 00:18:07,280 Speaker 1: Chuck that reading this maybe wonder like, are we gonna 300 00:18:07,320 --> 00:18:10,800 Speaker 1: go the other direction now where it's like we understand 301 00:18:10,800 --> 00:18:13,640 Speaker 1: that you can't just use antibiotics to get rid of everything. 302 00:18:14,160 --> 00:18:18,520 Speaker 1: But if we identify bacteria that's like, oh, well, that 303 00:18:18,560 --> 00:18:20,320 Speaker 1: one gives you cavities, let's get rid of all of 304 00:18:20,359 --> 00:18:22,800 Speaker 1: that and find some sort of medicine that just gets 305 00:18:22,880 --> 00:18:25,840 Speaker 1: rid of that, it could make things even worse than 306 00:18:25,840 --> 00:18:29,000 Speaker 1: a whole other direction. Like one thing that I fact 307 00:18:29,080 --> 00:18:32,400 Speaker 1: I figured out from this is that the the microbiome 308 00:18:32,440 --> 00:18:36,120 Speaker 1: appears to exist in balance, like stuff that should make 309 00:18:36,160 --> 00:18:40,080 Speaker 1: us sick E. Coli um, kinds of strepped staff, that 310 00:18:40,200 --> 00:18:43,040 Speaker 1: kind of thing, like it exists on a healthy person's 311 00:18:43,080 --> 00:18:46,960 Speaker 1: microbiome and it's just hanging out there. So it doesn't 312 00:18:47,000 --> 00:18:51,439 Speaker 1: mean that they're inherently disease causing for us, or that 313 00:18:51,480 --> 00:18:55,800 Speaker 1: they're they're inevitably disease causing UM. Apparently if they exist 314 00:18:55,840 --> 00:18:58,520 Speaker 1: in harmony with their neighbors. That's the way it's supposed 315 00:18:58,520 --> 00:19:01,080 Speaker 1: to be. And we can't just route out just ones 316 00:19:01,119 --> 00:19:02,760 Speaker 1: that make a sick and get rid of those because 317 00:19:02,760 --> 00:19:05,679 Speaker 1: I think it will have repercussions, But they might. We 318 00:19:05,760 --> 00:19:08,640 Speaker 1: might have a future where instead of an antibiotic you take, 319 00:19:09,040 --> 00:19:13,480 Speaker 1: you actually take a bacteria that will attack the other bacteria, 320 00:19:14,440 --> 00:19:17,080 Speaker 1: like the bad stuff, right, or you can write exactly 321 00:19:17,280 --> 00:19:21,240 Speaker 1: like that that as long as we're not intervening and 322 00:19:21,280 --> 00:19:25,680 Speaker 1: going after a specific bacteria, we can aid the bacteria 323 00:19:25,720 --> 00:19:28,520 Speaker 1: like you say that will fight it naturally, like by 324 00:19:28,760 --> 00:19:34,560 Speaker 1: eating some sort of sugary paste, you know, or probiotics. 325 00:19:34,600 --> 00:19:37,600 Speaker 1: I mean that's what that is, right, and that I mean, 326 00:19:37,760 --> 00:19:41,280 Speaker 1: that's that's an issue that's being um examined in in 327 00:19:41,480 --> 00:19:45,680 Speaker 1: more detailed thanks to the microbiome. Like do probiotics work? Uh? 328 00:19:45,720 --> 00:19:49,240 Speaker 1: And apparently the jury is still out like injury. They 329 00:19:49,240 --> 00:19:52,200 Speaker 1: should work, but it depends on you know, whether these 330 00:19:52,200 --> 00:19:55,639 Speaker 1: things are actually colonizing your guts. And also I have 331 00:19:55,760 --> 00:19:59,520 Speaker 1: the impression that it's like you don't really know what 332 00:19:59,600 --> 00:20:01,800 Speaker 1: you're do wing when you're adding like all these new 333 00:20:01,840 --> 00:20:05,719 Speaker 1: people of the neighborhood. Yeah, and because everyone's microbiome is 334 00:20:05,760 --> 00:20:09,600 Speaker 1: so different, some one probiotic for one person might be 335 00:20:09,680 --> 00:20:11,800 Speaker 1: great and for another person might not do anything or 336 00:20:11,880 --> 00:20:14,080 Speaker 1: may make things worse. I don't know. Yeah, which is 337 00:20:14,119 --> 00:20:18,080 Speaker 1: another goal of the Human Microbiome project that if we 338 00:20:18,119 --> 00:20:22,240 Speaker 1: start to understand, you know, what a colony. Maybe there's 339 00:20:22,280 --> 00:20:25,879 Speaker 1: not a normal colony for everybody, but what an individual's 340 00:20:25,920 --> 00:20:29,560 Speaker 1: normal colony looks like then you can take blood or 341 00:20:29,960 --> 00:20:33,720 Speaker 1: samples and make adjustments based specifically on what you need. 342 00:20:33,840 --> 00:20:38,160 Speaker 1: Right there, it could be the end of pharmaceutical drugs conceivably. 343 00:20:38,720 --> 00:20:42,119 Speaker 1: Another they're doing a lot of research into um, how 344 00:20:42,359 --> 00:20:46,880 Speaker 1: your gut bacteria affects obesity and your weight. Um. They 345 00:20:46,920 --> 00:20:52,760 Speaker 1: have found obese mice and transferred micro microbes from their 346 00:20:52,800 --> 00:20:56,119 Speaker 1: gut into skinny mice, and the skinny mice gained weight. 347 00:20:56,640 --> 00:21:01,600 Speaker 1: And um, there's just type in um gut bacteria and obesity, 348 00:21:01,680 --> 00:21:03,720 Speaker 1: and there are a lot of studies going on now 349 00:21:04,160 --> 00:21:07,040 Speaker 1: thinking that maybe correcting your gut bacteria could actually help 350 00:21:07,080 --> 00:21:10,879 Speaker 1: you help your metabolism, you know, straighten out right, Like 351 00:21:10,920 --> 00:21:16,080 Speaker 1: they think the bacteria itself directly informs how the body 352 00:21:16,320 --> 00:21:21,440 Speaker 1: uses their stores energy. Yeah. Um. The one that blew 353 00:21:21,480 --> 00:21:26,040 Speaker 1: me away was there's a type of um bacteria that 354 00:21:26,119 --> 00:21:30,720 Speaker 1: helps that helps break down milk in humans and typically 355 00:21:30,720 --> 00:21:33,879 Speaker 1: it's in the gut, but um, as a woman advances 356 00:21:33,880 --> 00:21:38,440 Speaker 1: in pregnancy, Uh, some of it moves down to the vagina. 357 00:21:38,960 --> 00:21:42,520 Speaker 1: And they at first, the researchers who found this were like, 358 00:21:42,600 --> 00:21:44,879 Speaker 1: what's the deal with that? And then they figured it out. 359 00:21:45,119 --> 00:21:48,439 Speaker 1: They think when a baby is born um, and it 360 00:21:48,520 --> 00:21:53,520 Speaker 1: passes through the vagina. It basically it's becomes covered in 361 00:21:53,560 --> 00:21:57,760 Speaker 1: this bacteria, ingests some of it, and that bacteria goes 362 00:21:57,800 --> 00:22:00,360 Speaker 1: down and colonizes the baby's guts and prepare is it 363 00:22:00,560 --> 00:22:04,320 Speaker 1: almost immediately to start breaking down breast milk. Yeah, evidently 364 00:22:05,080 --> 00:22:09,320 Speaker 1: brand new babies are just sponges. And like they're experimenting 365 00:22:09,359 --> 00:22:13,840 Speaker 1: with cesarean sections to just swab like after you have 366 00:22:13,920 --> 00:22:16,560 Speaker 1: the cesarian section, you bring the baby out, swab it 367 00:22:16,600 --> 00:22:21,760 Speaker 1: with with vaginal mucus and basically it just sucks right 368 00:22:21,760 --> 00:22:24,080 Speaker 1: into the skin and maybe have the same result or 369 00:22:24,119 --> 00:22:28,040 Speaker 1: swab their mouth or something like that. Yeah, um another way, 370 00:22:28,040 --> 00:22:31,240 Speaker 1: And I guess that's kind of related to is UM. 371 00:22:31,359 --> 00:22:36,160 Speaker 1: With the immune system. Apparently, the microbiome acts as kind 372 00:22:36,200 --> 00:22:40,040 Speaker 1: of like a teacher to the early immune system and 373 00:22:40,119 --> 00:22:42,520 Speaker 1: says like, hey, these are the good ones, these are 374 00:22:42,560 --> 00:22:45,280 Speaker 1: the bad ones. Um, why don't you go ahead and 375 00:22:45,320 --> 00:22:48,520 Speaker 1: produce some T killer cells or killer T cells, but 376 00:22:48,640 --> 00:22:52,639 Speaker 1: not too many um, and uh, we'll just go ahead 377 00:22:52,640 --> 00:22:55,600 Speaker 1: and keep the homeostasis going. And they basically like teach 378 00:22:56,160 --> 00:22:59,720 Speaker 1: a young immune system how to operate at an optimal 379 00:22:59,800 --> 00:23:03,760 Speaker 1: let hole. And they found that by engineering mice that 380 00:23:03,880 --> 00:23:07,560 Speaker 1: are like totally germ free, their immune systems have a 381 00:23:07,600 --> 00:23:12,040 Speaker 1: tendency to go crazy, like they'll become inflamed in the 382 00:23:12,080 --> 00:23:18,960 Speaker 1: presence of what are say, um, non harmful fungi. Um, 383 00:23:19,040 --> 00:23:22,040 Speaker 1: They'll they'll become so inflamed that they'll damage the surrounding 384 00:23:22,080 --> 00:23:26,800 Speaker 1: tissue or they'll have like irritable bowel syndrome or Crohn's disease. 385 00:23:26,840 --> 00:23:30,720 Speaker 1: They think also is a a flux state of the 386 00:23:30,840 --> 00:23:34,920 Speaker 1: microbiome in the gut, so apparently it directly impacts the 387 00:23:35,359 --> 00:23:38,800 Speaker 1: immune system as well, which my friend lends a lot 388 00:23:38,840 --> 00:23:43,160 Speaker 1: of weight to the hygiene hypothesis. Yeah, that's that's basically 389 00:23:43,240 --> 00:23:46,400 Speaker 1: the notion that uh here in the West and even 390 00:23:46,400 --> 00:23:51,920 Speaker 1: in developing countries now, children are seeing such a decrease 391 00:23:51,920 --> 00:23:55,360 Speaker 1: in infection when they're when their kids that when they 392 00:23:55,359 --> 00:23:59,520 Speaker 1: grow up they have an increased number of allergies and 393 00:23:59,560 --> 00:24:05,000 Speaker 1: maybe autoimmune issues, and um, you kind of see it 394 00:24:05,040 --> 00:24:07,800 Speaker 1: playing out, you know, like it it's a real thing. 395 00:24:07,880 --> 00:24:10,480 Speaker 1: Like if you're slathering your child with pure l you're 396 00:24:10,520 --> 00:24:13,359 Speaker 1: not doing them many favors, right, So they may have 397 00:24:13,400 --> 00:24:16,400 Speaker 1: asthma later on because of that exactly, and they are 398 00:24:16,440 --> 00:24:19,920 Speaker 1: becoming they're coming to think that it's because of the 399 00:24:19,920 --> 00:24:24,399 Speaker 1: the just a stunted growth of the microbiome. Yeah, and 400 00:24:24,440 --> 00:24:26,200 Speaker 1: I think they found now even they think they have 401 00:24:26,240 --> 00:24:30,920 Speaker 1: a direct link between your gut bacteria and allergies. So 402 00:24:31,040 --> 00:24:33,639 Speaker 1: if you're if you get hay fever, it may be 403 00:24:33,720 --> 00:24:37,000 Speaker 1: because of your gut bacteria. And it makes just utter 404 00:24:37,080 --> 00:24:40,560 Speaker 1: and complete sense too, Like your body has been exposed 405 00:24:40,560 --> 00:24:43,840 Speaker 1: to these things early on, learned that they're not harmful 406 00:24:44,280 --> 00:24:48,160 Speaker 1: and no longer produces antibodies as a result of their presence, 407 00:24:48,800 --> 00:24:51,680 Speaker 1: because that's all analogy is. It's a a m it's 408 00:24:51,720 --> 00:24:54,560 Speaker 1: a case of mistaken identity. Your immune system thinks that 409 00:24:54,840 --> 00:24:58,280 Speaker 1: pollen or something is a harmful for an invader and 410 00:24:58,400 --> 00:25:02,760 Speaker 1: launches your your immune response. Pretty cool. Uh. Some of 411 00:25:02,760 --> 00:25:05,080 Speaker 1: the other interesting things they found so far is that 412 00:25:06,440 --> 00:25:09,960 Speaker 1: there wasn't a single microbe that everyone had in the study, 413 00:25:10,280 --> 00:25:15,400 Speaker 1: which is pretty interesting. Um, And that microbes are most 414 00:25:15,440 --> 00:25:18,119 Speaker 1: similar on the same site of different people. So like 415 00:25:18,160 --> 00:25:20,960 Speaker 1: you and I have more similar microbes in our armpit 416 00:25:22,600 --> 00:25:25,880 Speaker 1: even there were different people. Right then you You're microbes 417 00:25:25,880 --> 00:25:28,199 Speaker 1: in your armpit has to do with your belly button. Yea, 418 00:25:28,920 --> 00:25:31,919 Speaker 1: ours are more similar than the ones in different places 419 00:25:31,960 --> 00:25:35,240 Speaker 1: on your body. Yeah, that's pretty neat. And different microbes 420 00:25:35,320 --> 00:25:38,880 Speaker 1: can do completely different things, like the way you digest 421 00:25:38,960 --> 00:25:43,520 Speaker 1: food might use one microbe and I might use another, 422 00:25:43,880 --> 00:25:46,320 Speaker 1: or that same microbe might have a completely different function 423 00:25:46,359 --> 00:25:49,080 Speaker 1: in you than it doesn't mean, right, So it's so personalized. 424 00:25:49,119 --> 00:25:52,520 Speaker 1: It's like, it feels like the beginning of like hyper 425 00:25:52,520 --> 00:25:56,680 Speaker 1: personalized medicine. I think it is in the future, I 426 00:25:56,720 --> 00:25:59,520 Speaker 1: definitely think is. I think it's also the beginning of 427 00:25:59,560 --> 00:26:05,560 Speaker 1: a kind indler, kinder gentler approach to treating disease at all, disease, like, 428 00:26:05,640 --> 00:26:08,240 Speaker 1: it's entirely possible, especially if you take a brain based 429 00:26:08,320 --> 00:26:12,679 Speaker 1: view of mental illness. It's possible that every bit of 430 00:26:12,760 --> 00:26:17,560 Speaker 1: disease can be cured by by understanding the microbiome, even cancer. 431 00:26:17,600 --> 00:26:21,240 Speaker 1: Apparently they found from this that some types of cancer 432 00:26:21,880 --> 00:26:27,000 Speaker 1: managed to cloak themselves by taking like um resin or 433 00:26:27,119 --> 00:26:31,159 Speaker 1: residue from certain types of bacteria and basically sneaking past 434 00:26:31,280 --> 00:26:36,560 Speaker 1: your your immune system and going and lodging itself into 435 00:26:36,640 --> 00:26:39,720 Speaker 1: cells and hijacking them and creating tumors. But it cloaks 436 00:26:39,760 --> 00:26:43,240 Speaker 1: itself by getting buddy buddy with certain kinds of bacteria. 437 00:26:43,560 --> 00:26:46,400 Speaker 1: Cancer is a jerk. Yes, cancer is a big time jerk. 438 00:26:46,520 --> 00:26:48,200 Speaker 1: You know, we've kind of covered it here and there, 439 00:26:48,240 --> 00:26:52,080 Speaker 1: but I could see more specific cancer podcasting our futures, 440 00:26:53,080 --> 00:26:55,760 Speaker 1: you know what. So Like, so far we've done to 441 00:26:56,200 --> 00:26:59,080 Speaker 1: that specifically got into the microbiome, but we've never done 442 00:26:59,119 --> 00:27:02,400 Speaker 1: like a microbiome one. So I think we should come back, 443 00:27:02,440 --> 00:27:04,440 Speaker 1: like a year from now and even more stuff is 444 00:27:04,480 --> 00:27:07,399 Speaker 1: out and do like the microbiome. Yeah, it seems like 445 00:27:07,400 --> 00:27:10,680 Speaker 1: they're they're making breakthroughs at a pretty rapid pace. Yes, 446 00:27:10,800 --> 00:27:15,439 Speaker 1: so in a year they might everyone might be skinny. Yeah, 447 00:27:15,480 --> 00:27:18,320 Speaker 1: because of the microbiome pill. Have you seen a picture 448 00:27:18,359 --> 00:27:20,879 Speaker 1: of like an obese mouse next to like a skinny 449 00:27:20,920 --> 00:27:25,679 Speaker 1: or normal sized mouse. It's pretty depressing. Um sad mouse. Okay, 450 00:27:25,680 --> 00:27:28,000 Speaker 1: So I will see you here at the end of 451 00:27:28,080 --> 00:27:32,520 Speaker 1: next April. Uh, God willing for the microbiome on deal? 452 00:27:32,680 --> 00:27:34,480 Speaker 1: All right, if you want to learn more about the 453 00:27:34,520 --> 00:27:38,040 Speaker 1: human microbiome, you can type that well those words into 454 00:27:38,080 --> 00:27:40,800 Speaker 1: the search part how stuff works dot com? Uh, And 455 00:27:40,840 --> 00:27:43,120 Speaker 1: I said how stuff works dot com. So it's time 456 00:27:43,160 --> 00:27:47,760 Speaker 1: for the listener mail. Josh, I'm gonna call this response 457 00:27:47,800 --> 00:27:51,080 Speaker 1: from a creationist. Okay, we got a few of these, 458 00:27:52,480 --> 00:27:54,880 Speaker 1: Hey guys, listen to your podcast on natural selection and 459 00:27:54,920 --> 00:27:57,520 Speaker 1: really enjoyed it. I'm a biologist who is a Christian 460 00:27:57,600 --> 00:28:01,480 Speaker 1: and creationist. Natural selection is not what we disagree on, 461 00:28:01,880 --> 00:28:04,560 Speaker 1: and when I say we, I mean most creationists, but 462 00:28:04,640 --> 00:28:07,719 Speaker 1: of course with every group their outliers. We agree with 463 00:28:07,800 --> 00:28:11,879 Speaker 1: micro evolution changes that occur within the species, not macro 464 00:28:12,040 --> 00:28:16,960 Speaker 1: evolution species developed into a completely different species, which is 465 00:28:17,000 --> 00:28:19,840 Speaker 1: what most people tend to associate with evolution. The only 466 00:28:19,840 --> 00:28:23,800 Speaker 1: major differences between creationists and evolutionists is that we believe 467 00:28:23,840 --> 00:28:26,800 Speaker 1: the Earth is between six and ten thousand years old 468 00:28:27,560 --> 00:28:31,560 Speaker 1: UM and again excluding the outliers, and that all organisms 469 00:28:31,600 --> 00:28:35,480 Speaker 1: were created in their basic form by our God. For example, 470 00:28:35,520 --> 00:28:37,960 Speaker 1: we believe that everyone came from Adam and Eve, who 471 00:28:37,960 --> 00:28:42,000 Speaker 1: through methods of natural selection, evolved into the many nationalities 472 00:28:42,040 --> 00:28:44,440 Speaker 1: we have today. Same thing with animals. We believe that 473 00:28:44,480 --> 00:28:47,440 Speaker 1: a small number of species were created by our God, 474 00:28:47,920 --> 00:28:50,880 Speaker 1: and all the forms we have today evolved through natural selection. 475 00:28:51,320 --> 00:28:54,240 Speaker 1: So the only main difference that we have with evolutionists 476 00:28:54,800 --> 00:28:58,000 Speaker 1: is the ultimate origin of species, the areas of evolution 477 00:28:58,040 --> 00:29:00,600 Speaker 1: that we can see clearly occurring and run of our eyes, 478 00:29:00,640 --> 00:29:03,760 Speaker 1: we agree with. It's the areas the evolutionists theorized about 479 00:29:03,800 --> 00:29:06,800 Speaker 1: that we don't agree with. So while there are differences 480 00:29:06,840 --> 00:29:10,920 Speaker 1: between creationism and evolution, they're actually more similarities. And that 481 00:29:11,080 --> 00:29:14,920 Speaker 1: is Eric from South Bend, Indiana. Thanks a lot, Eric, 482 00:29:15,360 --> 00:29:19,080 Speaker 1: very salient points biologists. Yeah, I love it when like 483 00:29:19,720 --> 00:29:22,760 Speaker 1: experts come out of the out of the woodwork, especially 484 00:29:23,080 --> 00:29:26,880 Speaker 1: when they're experts with a twist. Yes, And we love 485 00:29:27,400 --> 00:29:31,640 Speaker 1: being refuted and refuting and reading refutations, and uh, we'll 486 00:29:31,640 --> 00:29:35,640 Speaker 1: always read these things refutation life. That's right. 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