1 00:00:00,320 --> 00:00:03,000 Speaker 1: Brought to you by the reinvented two thousand twelve Camray. 2 00:00:03,240 --> 00:00:10,000 Speaker 1: It's ready. Are you welcome to stop? Mom never told you? 3 00:00:10,200 --> 00:00:17,880 Speaker 1: From how Stuff Works dot Com, Hey, welcome the podcast. 4 00:00:17,920 --> 00:00:20,360 Speaker 1: This is Molly and I'm Kristen Christon's day. We're going 5 00:00:20,400 --> 00:00:24,639 Speaker 1: to discuss polycystic ovary syndrome. And this has been a 6 00:00:24,640 --> 00:00:26,680 Speaker 1: red class sort of almost from the beginning of the 7 00:00:26,720 --> 00:00:28,760 Speaker 1: time we started the podcast. But I'm kind of glad 8 00:00:28,800 --> 00:00:31,800 Speaker 1: you waited, if only because all of the elements that 9 00:00:31,880 --> 00:00:35,559 Speaker 1: go in to polycystic overary syndrome or p COST as 10 00:00:35,560 --> 00:00:39,280 Speaker 1: we'll be calling it, reflect on things we've already talked about, 11 00:00:39,680 --> 00:00:44,400 Speaker 1: for example, women and their insecurity or security over hair 12 00:00:45,040 --> 00:00:51,279 Speaker 1: embody hair, uh security and insecurity about menstruation, how difficult 13 00:00:51,320 --> 00:00:56,400 Speaker 1: that is to talk about acne, in fertility, like everything 14 00:00:56,440 --> 00:01:00,240 Speaker 1: that we've ever mentioned about things that are hard to 15 00:01:00,480 --> 00:01:03,440 Speaker 1: accept or to get just right in this society about 16 00:01:03,480 --> 00:01:06,880 Speaker 1: being a woman, they come into play in this condition. 17 00:01:07,240 --> 00:01:09,120 Speaker 1: So I'm kind of gladuated because we when we talked 18 00:01:09,160 --> 00:01:12,600 Speaker 1: then about how hard it is to like have you know, 19 00:01:12,720 --> 00:01:16,840 Speaker 1: certain you know conditions, it will reflect back on the 20 00:01:16,840 --> 00:01:20,640 Speaker 1: difficulty we've discussed before. I think You're exactly right, and uh, 21 00:01:20,800 --> 00:01:24,280 Speaker 1: picos has actually been around for a while, even though 22 00:01:24,400 --> 00:01:26,720 Speaker 1: it sounds like from the research, Molly that you and 23 00:01:26,760 --> 00:01:31,000 Speaker 1: I've done, it's really only come into the forefront of 24 00:01:31,160 --> 00:01:36,360 Speaker 1: women's medicine in the past uh ten or so years UM. 25 00:01:36,480 --> 00:01:40,440 Speaker 1: It was initially discovered or identified, if you will, around 26 00:01:40,480 --> 00:01:43,440 Speaker 1: seventy years ago UM, and it used to be called 27 00:01:43,520 --> 00:01:48,160 Speaker 1: stein Levinthal syndrome after the two doctors who discovered it 28 00:01:48,400 --> 00:01:52,600 Speaker 1: in ninety five. And it affects as many as ten 29 00:01:52,680 --> 00:01:56,960 Speaker 1: percent of women, but it goes largely unrecognized for reasons 30 00:01:57,000 --> 00:02:00,960 Speaker 1: that we'll get into later in this podcast. Because rather 31 00:02:01,000 --> 00:02:06,320 Speaker 1: than having one single symptom, one identifiable symptom like an 32 00:02:06,360 --> 00:02:10,680 Speaker 1: irregular period or trouble getting pregnant, it is a host 33 00:02:11,240 --> 00:02:16,320 Speaker 1: of symptoms and researchers aren't even sure exactly why picos 34 00:02:16,400 --> 00:02:18,680 Speaker 1: happens in the first place. They have some ideas, but 35 00:02:18,720 --> 00:02:21,560 Speaker 1: they're not really sure, and it can be pretty challenging 36 00:02:21,600 --> 00:02:25,440 Speaker 1: to identify what The good thing is that more doctors 37 00:02:25,480 --> 00:02:28,880 Speaker 1: are starting to pay attention to it, look for these 38 00:02:28,919 --> 00:02:33,160 Speaker 1: symptoms and get women the treatment that they need because picos, 39 00:02:33,240 --> 00:02:36,640 Speaker 1: as Molly, you and I've have, really discovered through our research. 40 00:02:36,800 --> 00:02:41,520 Speaker 1: Is not a pleasant syndrome. I would say it's downright 41 00:02:41,560 --> 00:02:45,440 Speaker 1: awful because it sounds pretty awful. Let's go over the symptoms, 42 00:02:45,480 --> 00:02:48,080 Speaker 1: because I think that will demonstrate to listeners just what 43 00:02:48,120 --> 00:02:50,720 Speaker 1: we're dealing with here in terms of stigma and in 44 00:02:50,840 --> 00:02:54,200 Speaker 1: terms of difficulty just living your life. UM. As the 45 00:02:54,280 --> 00:02:57,200 Speaker 1: name implies, something's going on with your ovaries. You have 46 00:02:57,320 --> 00:03:01,480 Speaker 1: these tiny bubble cysts on your ovary and they're the 47 00:03:01,520 --> 00:03:06,120 Speaker 1: result of eggs that didn't quite descend to become a 48 00:03:06,160 --> 00:03:09,600 Speaker 1: menstrual period and they just kind of sit there on 49 00:03:09,880 --> 00:03:13,320 Speaker 1: your ovaries. And as that implies, you have a regular 50 00:03:13,360 --> 00:03:18,920 Speaker 1: menstruation and UM, this is classified as a metabolic disorder 51 00:03:19,560 --> 00:03:23,160 Speaker 1: UM due to abnormal hormone levels UM and it's the 52 00:03:23,240 --> 00:03:26,720 Speaker 1: hormones are f s H and l H, which are 53 00:03:26,760 --> 00:03:31,840 Speaker 1: created by your pituitary gland that really control your menstrual cycle, 54 00:03:32,280 --> 00:03:36,960 Speaker 1: and this imbalance can lead to a host of symptoms 55 00:03:37,000 --> 00:03:42,840 Speaker 1: including infertility, obesity, acne, excessive facial hair and body hair, diabetes, 56 00:03:43,280 --> 00:03:47,160 Speaker 1: heart disease, and uterine cancer. Yes, so these hormones that 57 00:03:47,240 --> 00:03:51,000 Speaker 1: Kristen mentioned, follicle stimulating hormone f s H and LH 58 00:03:51,160 --> 00:03:55,040 Speaker 1: lutenizing hormone. If everything's working correctly, they're the ones that 59 00:03:55,080 --> 00:03:57,320 Speaker 1: are gonna say, hey, ovaries, you need to release an 60 00:03:57,400 --> 00:04:00,360 Speaker 1: egg and if that expertilize and you can have a baby. 61 00:04:00,360 --> 00:04:02,800 Speaker 1: And if it's not, then there'll be a menstrual period. 62 00:04:03,480 --> 00:04:06,240 Speaker 1: So when these hormones are out of whack, then you 63 00:04:06,240 --> 00:04:09,600 Speaker 1: don't have the period and that will affect UH fertility 64 00:04:09,640 --> 00:04:14,440 Speaker 1: down the line. Right, and LH and FSH also regulate 65 00:04:14,480 --> 00:04:20,320 Speaker 1: the ovaries production of estrogen, progesterone, and testosterone, and so 66 00:04:20,400 --> 00:04:23,560 Speaker 1: all of the it starts this ripple effect where all 67 00:04:23,600 --> 00:04:27,279 Speaker 1: of these different hormones are out of balance and produce 68 00:04:27,400 --> 00:04:34,480 Speaker 1: this wide range can produces wide range of really uncomfortable symptoms. Right, 69 00:04:34,520 --> 00:04:37,360 Speaker 1: because the blood levels of testosterone are what can cause 70 00:04:38,080 --> 00:04:42,159 Speaker 1: dark corse facial hair UH baldness. There might be a 71 00:04:42,560 --> 00:04:46,120 Speaker 1: patches of dark skin around the neck and the chest. 72 00:04:46,839 --> 00:04:50,040 Speaker 1: And then complicating all of this, we've got a problem 73 00:04:50,080 --> 00:04:54,400 Speaker 1: with insulin because insulince primary task is to maintain your 74 00:04:54,400 --> 00:04:57,359 Speaker 1: blood level glucose, and it moves the sugar, helps you 75 00:04:57,400 --> 00:05:01,680 Speaker 1: digest carbohydrates UH the best ways that it makes it 76 00:05:01,720 --> 00:05:05,040 Speaker 1: into energy. But insulin also deals with storage of fats 77 00:05:05,040 --> 00:05:08,760 Speaker 1: so if you've got really high levels of insulin, then 78 00:05:08,839 --> 00:05:11,480 Speaker 1: you might gain weight even if you're eating healthfully, and 79 00:05:11,560 --> 00:05:13,520 Speaker 1: you might have a lot of trouble losing weights. So 80 00:05:13,839 --> 00:05:17,480 Speaker 1: one of the big symptoms of peacos is obesity. Half 81 00:05:17,520 --> 00:05:21,640 Speaker 1: of women with peacos at least have OBEs. And it's 82 00:05:21,680 --> 00:05:24,839 Speaker 1: not like a gradual thing, you know, reading some of 83 00:05:24,880 --> 00:05:28,080 Speaker 1: these accounts, it's like over six weeks when WU put 84 00:05:28,080 --> 00:05:30,760 Speaker 1: on fifty pounds. It's it's a really sudden change in 85 00:05:30,839 --> 00:05:35,599 Speaker 1: your insulin production and levels that can uh, you know, 86 00:05:35,839 --> 00:05:38,320 Speaker 1: just take you on a weight roller coaster, right, And 87 00:05:38,400 --> 00:05:42,200 Speaker 1: when the pancreas starts to overproduce insulin to such extremes 88 00:05:42,240 --> 00:05:45,960 Speaker 1: like this, it can also lead to type two diabetes. 89 00:05:46,080 --> 00:05:49,040 Speaker 1: So as you can see, there's like this chain reaction 90 00:05:49,480 --> 00:05:56,400 Speaker 1: of of symptoms all relating back to these hormone imbalances. 91 00:05:56,440 --> 00:05:58,480 Speaker 1: And we should point out that not every woman with 92 00:05:58,480 --> 00:06:02,120 Speaker 1: pecos will it at the same types of symptoms were 93 00:06:02,200 --> 00:06:07,640 Speaker 1: kind of painting the worst case scenario. But nevertheless, it's 94 00:06:08,360 --> 00:06:10,080 Speaker 1: not a fun thing to happen. I mean, if you 95 00:06:10,080 --> 00:06:12,200 Speaker 1: think about just one of them, it's one of those 96 00:06:12,240 --> 00:06:15,000 Speaker 1: symptoms is enough to cripple your life. You know, you 97 00:06:15,120 --> 00:06:17,360 Speaker 1: wouldn't want to go outside if you've got facial hair 98 00:06:17,480 --> 00:06:20,960 Speaker 1: thanks to the testosterone. Acne is already a big struggle 99 00:06:21,240 --> 00:06:24,240 Speaker 1: even without the stress of having a regular periods. You know, 100 00:06:24,720 --> 00:06:26,600 Speaker 1: as I said, all these things we've talked about in 101 00:06:26,640 --> 00:06:29,560 Speaker 1: the past being difficult for women, and for adolescent women 102 00:06:29,560 --> 00:06:33,880 Speaker 1: in particular, they're all compounded and put into this one syndrome. 103 00:06:33,960 --> 00:06:36,840 Speaker 1: And I think that that is why it's really hard 104 00:06:36,880 --> 00:06:39,919 Speaker 1: to get a diagnosis, because who wants to go to 105 00:06:39,960 --> 00:06:42,960 Speaker 1: their doctor and say, hey, what's the deal with the 106 00:06:43,000 --> 00:06:45,000 Speaker 1: facial hair, what's the deal with the fact that I'm 107 00:06:45,000 --> 00:06:48,479 Speaker 1: not having regular periods? Because I think that some of 108 00:06:48,520 --> 00:06:51,600 Speaker 1: these symptoms you have the tendency to dismiss, especially when 109 00:06:51,640 --> 00:06:53,520 Speaker 1: you're young girl. People tell you it'll take a while 110 00:06:53,600 --> 00:06:56,760 Speaker 1: to get your periods on a regular track. They tell 111 00:06:56,800 --> 00:06:58,719 Speaker 1: you that acne is due to stress and it's a 112 00:06:58,760 --> 00:07:01,200 Speaker 1: normal part of growing up. So there are some of 113 00:07:01,200 --> 00:07:04,719 Speaker 1: these symptoms are thought to be so, you know, part 114 00:07:04,720 --> 00:07:06,960 Speaker 1: of a rite of passage, whereas the other ones are 115 00:07:07,040 --> 00:07:10,600 Speaker 1: so scary and out of the norm that when you 116 00:07:11,040 --> 00:07:14,560 Speaker 1: put them all together, it's very uh, very difficult for 117 00:07:14,600 --> 00:07:16,680 Speaker 1: a woman to a come to their doctor and then 118 00:07:16,720 --> 00:07:19,840 Speaker 1: be for the doctor to figure out what's going on, right, 119 00:07:19,920 --> 00:07:22,800 Speaker 1: because also some of these symptoms can also apply to 120 00:07:22,840 --> 00:07:27,120 Speaker 1: other serious disorders like tumors or you know, the doctor 121 00:07:27,200 --> 00:07:31,800 Speaker 1: might spot the sudden spike and weight and also dark 122 00:07:31,840 --> 00:07:34,520 Speaker 1: overgrown skin at the base of your neck which is 123 00:07:34,520 --> 00:07:37,960 Speaker 1: a sign of an insulin problem and say that you 124 00:07:38,320 --> 00:07:42,360 Speaker 1: might have diabetes and completely bypass the picos issue. And 125 00:07:42,480 --> 00:07:46,200 Speaker 1: Molly and I found an article from Science Stanley that 126 00:07:46,240 --> 00:07:49,520 Speaker 1: was really highlighting the work of um one kinnecologist who's 127 00:07:49,520 --> 00:07:53,760 Speaker 1: trying to get Pico's research out into the forefront more. 128 00:07:53,840 --> 00:07:56,840 Speaker 1: And she said that a lot of times women will 129 00:07:56,960 --> 00:07:59,840 Speaker 1: have to go to an average of four doctors before 130 00:08:00,000 --> 00:08:03,400 Speaker 1: they're correctly diagnosed. And this is happening to about five 131 00:08:03,440 --> 00:08:08,080 Speaker 1: million women in the US who are affected by pekos. Yes, 132 00:08:08,160 --> 00:08:10,440 Speaker 1: so these women go to doctors and are told, oh, 133 00:08:10,480 --> 00:08:12,280 Speaker 1: this is just a weight problem, or that this is 134 00:08:12,320 --> 00:08:15,400 Speaker 1: just an acne problem. And then to add fuel to fire, 135 00:08:15,600 --> 00:08:19,080 Speaker 1: this researcher Andrew D. Knife who's at Northwestern says that 136 00:08:19,120 --> 00:08:23,880 Speaker 1: because the condition has ovary in the name, you know, 137 00:08:23,960 --> 00:08:26,760 Speaker 1: it's sort of relegated to this back burner of you know, 138 00:08:27,120 --> 00:08:30,960 Speaker 1: female troubles women's issues. You know, it's hard to confront 139 00:08:31,080 --> 00:08:34,160 Speaker 1: problems with menstrual cycles straight on, just because you know, 140 00:08:34,200 --> 00:08:36,880 Speaker 1: one's talking about it, as we discussed in the Menstruation 141 00:08:36,920 --> 00:08:41,080 Speaker 1: Taboo episode. So she wants to get peakos renamed. She 142 00:08:41,200 --> 00:08:44,360 Speaker 1: likes the name syndrome x X. I don't love that name, 143 00:08:44,440 --> 00:08:48,720 Speaker 1: but split hairs, Yeah, yeah, said, it's gravity er, you know, 144 00:08:48,800 --> 00:08:52,600 Speaker 1: than pekos, and you know, pecos is kind of a mouthful. 145 00:08:52,640 --> 00:08:57,120 Speaker 1: But one of the main problems too with this diagnosis 146 00:08:57,320 --> 00:09:01,240 Speaker 1: is that physicians aren't sure whether or not it's caused 147 00:09:01,240 --> 00:09:06,680 Speaker 1: by environmental or genetic factors, because there's there's sort of 148 00:09:07,000 --> 00:09:09,960 Speaker 1: two different camps on this uh, one camp thinking that 149 00:09:10,000 --> 00:09:12,280 Speaker 1: it might have to do with the defect within the 150 00:09:12,360 --> 00:09:16,439 Speaker 1: ovary or if it's due to the abnormal insulin activity. 151 00:09:16,480 --> 00:09:22,040 Speaker 1: And there's even um a split between American and European 152 00:09:22,080 --> 00:09:26,679 Speaker 1: definitions of picos and the different um symptomatic criteria they 153 00:09:26,679 --> 00:09:31,559 Speaker 1: have for diagnosing this, which I was kind of fascinated 154 00:09:31,600 --> 00:09:34,480 Speaker 1: by because not only is there just sort of this 155 00:09:34,800 --> 00:09:37,400 Speaker 1: kind of knowledge based divide, but also just a straight 156 00:09:37,480 --> 00:09:40,760 Speaker 1: up geographical divide and what actually is and is not 157 00:09:40,840 --> 00:09:43,079 Speaker 1: considered picos, I know, and you know, this goes back 158 00:09:43,120 --> 00:09:46,600 Speaker 1: to the name polycystic ovary syndrome. You know, not all 159 00:09:46,640 --> 00:09:50,160 Speaker 1: women who have other symptoms even have the cysts on 160 00:09:50,160 --> 00:09:53,360 Speaker 1: their ovaries, and that kind of leads us well into 161 00:09:53,400 --> 00:09:58,040 Speaker 1: this discussion of you know, the very definition is is 162 00:09:58,080 --> 00:10:01,280 Speaker 1: skewed depending on where you are. Basically what happened is 163 00:10:01,480 --> 00:10:04,000 Speaker 1: in ninety there's this big being in the United States 164 00:10:04,160 --> 00:10:08,680 Speaker 1: and the National Institute Tutes of Health established the criteria 165 00:10:08,920 --> 00:10:12,160 Speaker 1: of what they thought peak host was. Then, uh, you know, 166 00:10:12,400 --> 00:10:15,160 Speaker 1: in two thousand three, these positions in Europe got together 167 00:10:15,240 --> 00:10:17,800 Speaker 1: and they were like these you know that that criteria 168 00:10:17,840 --> 00:10:19,640 Speaker 1: is really doing it for us. We're gonna issue our 169 00:10:19,720 --> 00:10:23,559 Speaker 1: own criteria. And so now there's the two thousand three 170 00:10:23,640 --> 00:10:26,560 Speaker 1: Rotter Damn criteria is how you'll here referred to, and 171 00:10:26,640 --> 00:10:30,920 Speaker 1: the and I AH criteria. And because you know one 172 00:10:31,000 --> 00:10:32,520 Speaker 1: was sort of a European thing, a wast a u 173 00:10:32,640 --> 00:10:35,320 Speaker 1: S thing, you know, the the definition that might be 174 00:10:35,440 --> 00:10:38,360 Speaker 1: used will really depend on where you are. And uh, 175 00:10:38,440 --> 00:10:41,520 Speaker 1: let's go over the criteria to be uh nine and 176 00:10:41,559 --> 00:10:44,880 Speaker 1: I aged criteria to be a diagnosed with peak hosts, 177 00:10:44,880 --> 00:10:49,679 Speaker 1: then you would have hyper hyper androgenism, which refers to 178 00:10:49,800 --> 00:10:53,120 Speaker 1: the levels of hormones. They're gonna find your bloodstream a regular, 179 00:10:53,240 --> 00:10:57,400 Speaker 1: a regular ovulation and menstruation and exclusion of related disorders. 180 00:10:57,400 --> 00:10:59,560 Speaker 1: So if they can rule out, you know, the diabetes 181 00:10:59,800 --> 00:11:03,440 Speaker 1: or um just other problems with your menstrual cycle. So 182 00:11:03,520 --> 00:11:06,480 Speaker 1: that's that's one thing. But the Rotterdam people came in 183 00:11:06,520 --> 00:11:08,679 Speaker 1: and said, Okay, yeah, we're gonna go with that irregular 184 00:11:08,920 --> 00:11:12,600 Speaker 1: ovulation or no ovulation at all. We're gonna go with 185 00:11:12,679 --> 00:11:16,120 Speaker 1: the biochemical clinical signs of the hyperandrogenism. So the things 186 00:11:16,160 --> 00:11:19,640 Speaker 1: like the facial hair, the acne, the dark the dark 187 00:11:19,679 --> 00:11:23,079 Speaker 1: patches of skin, and we're gonna include the polycystic ovaries. 188 00:11:23,160 --> 00:11:25,760 Speaker 1: But you only have to have two of those three, right, 189 00:11:25,800 --> 00:11:30,559 Speaker 1: So the Rotterdam essentially Rotterdamn criteria essentially opened up the 190 00:11:30,600 --> 00:11:34,720 Speaker 1: criteria for peaks because they thought that the NIH definition 191 00:11:34,760 --> 00:11:37,360 Speaker 1: would just be a little too a little too narrow, 192 00:11:37,559 --> 00:11:40,720 Speaker 1: and so under Rotterdamn criteria, a lot more women have 193 00:11:40,960 --> 00:11:43,920 Speaker 1: peak hosts, but they might have more minor cases of 194 00:11:43,960 --> 00:11:45,880 Speaker 1: it because you don't have to meet as many of 195 00:11:45,960 --> 00:11:50,920 Speaker 1: the clinical criteria. But you know, there's also this problem 196 00:11:50,920 --> 00:11:55,600 Speaker 1: of polycystic overies is one of the elements of Rotterdamn criteria. 197 00:11:55,760 --> 00:11:58,800 Speaker 1: And if you're going to let's say an indo chronologists, 198 00:11:58,960 --> 00:12:01,560 Speaker 1: they may not do the ultrasound that finds that. So 199 00:12:01,679 --> 00:12:05,120 Speaker 1: it kind of gets thin into which doctor are you seeing. 200 00:12:05,200 --> 00:12:07,480 Speaker 1: You know, Kristen mentioned you have to see four doctors 201 00:12:07,920 --> 00:12:09,920 Speaker 1: and they may not all be within the same field 202 00:12:09,920 --> 00:12:13,040 Speaker 1: of gynecology or you know, if you have the acting, 203 00:12:13,120 --> 00:12:16,360 Speaker 1: you might have started with a dermatologist. Um, not all 204 00:12:16,400 --> 00:12:18,040 Speaker 1: of them are going to be equipped to find the 205 00:12:18,080 --> 00:12:22,280 Speaker 1: polycystic ovaries right away, and if they're not causing you pain. Uh, 206 00:12:22,320 --> 00:12:23,959 Speaker 1: And if you just start thinking that, oh, I have 207 00:12:24,000 --> 00:12:27,199 Speaker 1: a regular period because people say that's normal, you may 208 00:12:27,200 --> 00:12:29,240 Speaker 1: not have figured out that that's one of your symptoms yet. 209 00:12:29,280 --> 00:12:31,880 Speaker 1: So it's it really does come down to which doctor 210 00:12:31,920 --> 00:12:34,920 Speaker 1: you see and which criteria they're using, and whether they're 211 00:12:34,920 --> 00:12:38,400 Speaker 1: equipped to figure out something like polycystic overies with an 212 00:12:38,440 --> 00:12:42,800 Speaker 1: ultrasound or a with the exam. So let's say that 213 00:12:43,120 --> 00:12:47,000 Speaker 1: a woman is experiencing these types of symptoms and she 214 00:12:47,400 --> 00:12:52,160 Speaker 1: is diagnosed with picos um. Even though there isn't necessarily 215 00:12:52,240 --> 00:12:55,760 Speaker 1: a cure if you will for picos there are treatments 216 00:12:55,760 --> 00:13:00,240 Speaker 1: that have been proven to reduce these symptoms and a 217 00:13:00,280 --> 00:13:02,319 Speaker 1: lot of times a doctor and this is coming from 218 00:13:02,360 --> 00:13:05,760 Speaker 1: a really good overview article from the New York Times. UM, 219 00:13:05,800 --> 00:13:08,480 Speaker 1: a lot of times women will be tested for blood 220 00:13:08,559 --> 00:13:13,959 Speaker 1: levels of prolactin, for LH and F s H, progesterone, testosterone, 221 00:13:14,000 --> 00:13:17,920 Speaker 1: all of those different hormones, insulin, her ability to process blood, 222 00:13:17,920 --> 00:13:21,280 Speaker 1: glue close glucose excuse me, UM, all of those different 223 00:13:22,480 --> 00:13:27,560 Speaker 1: chemicals that are regulating these different types of symptoms. And 224 00:13:28,280 --> 00:13:30,320 Speaker 1: while treatments are going to be very just like the 225 00:13:30,360 --> 00:13:34,160 Speaker 1: types of symptoms that women are experiencing. So let's say 226 00:13:34,200 --> 00:13:36,800 Speaker 1: that you are a woman experiencing some are all of 227 00:13:36,800 --> 00:13:40,920 Speaker 1: these symptoms, You go to your doctor, your doctor diagnoses 228 00:13:40,960 --> 00:13:46,800 Speaker 1: you with pekos. What happens next, Um, there is a 229 00:13:46,840 --> 00:13:50,600 Speaker 1: pretty common treatment for it, which I was surprised UH 230 00:13:50,920 --> 00:13:53,520 Speaker 1: is birth control. A lot of times they will put 231 00:13:53,600 --> 00:13:58,800 Speaker 1: you on UH oral contraceptive in particular that contain quote 232 00:13:59,200 --> 00:14:04,600 Speaker 1: low and genic progestins like ortho tricycline or ortho cycling 233 00:14:04,679 --> 00:14:07,400 Speaker 1: excuse me, an ovulan, and these are gonna regulate your 234 00:14:07,400 --> 00:14:13,720 Speaker 1: menstrual cycle, suppress your follicle, stimulating hormone and lutinizing hormone release. 235 00:14:13,760 --> 00:14:17,200 Speaker 1: Which were those two hormones that we we mentioned right 236 00:14:17,200 --> 00:14:19,960 Speaker 1: at the beginning of the podcast that really seemed to 237 00:14:20,640 --> 00:14:24,040 Speaker 1: regulate all of these UH that chain reaction of negative 238 00:14:24,040 --> 00:14:27,160 Speaker 1: symptoms throughout your body. They're also going to lower the 239 00:14:27,200 --> 00:14:30,080 Speaker 1: testosterone level, which is going to help with symptoms like 240 00:14:30,120 --> 00:14:33,440 Speaker 1: your acne, excessive hair growth and all of that. And 241 00:14:33,440 --> 00:14:36,120 Speaker 1: then it's also going to raise level of protective cholesterol 242 00:14:36,440 --> 00:14:39,280 Speaker 1: and protect the uterine lining. And the uterine lining is 243 00:14:39,320 --> 00:14:42,960 Speaker 1: important because that's what builds up during your menstrual cycle 244 00:14:43,520 --> 00:14:46,880 Speaker 1: UH to receive a fertilized egg, and if the egg 245 00:14:46,920 --> 00:14:50,600 Speaker 1: doesn't drop down, then you shed it during menstruation. And 246 00:14:50,640 --> 00:14:54,760 Speaker 1: so oral contraceptives have been shown to be helpful. And 247 00:14:54,800 --> 00:14:58,400 Speaker 1: I should note that this information is coming from a 248 00:14:58,480 --> 00:15:01,840 Speaker 1: great overview article that we found from the New York Times, right, 249 00:15:01,880 --> 00:15:04,360 Speaker 1: And so let's really quick talk about for women who 250 00:15:04,360 --> 00:15:06,640 Speaker 1: are trying to get pregnant. Lee peaks is a really 251 00:15:06,680 --> 00:15:09,760 Speaker 1: big issue, and like Christen said, it protects that uterine 252 00:15:09,800 --> 00:15:12,960 Speaker 1: lining and makes it easier for a woman to get pregnant. 253 00:15:13,080 --> 00:15:16,000 Speaker 1: And um, so if a woman is trying to become pregnant, 254 00:15:16,080 --> 00:15:18,800 Speaker 1: they will have women take the pill and then try 255 00:15:18,840 --> 00:15:22,120 Speaker 1: to get pregnant immediately after she stops the pill, because 256 00:15:22,720 --> 00:15:24,800 Speaker 1: if if if it goes on too long, then those 257 00:15:24,800 --> 00:15:28,200 Speaker 1: hormone levels get back out of whack. And UH. They 258 00:15:28,240 --> 00:15:32,600 Speaker 1: also use the ovulation simulian drug Clomad when the woman 259 00:15:32,680 --> 00:15:34,960 Speaker 1: is trying to get pregnant, and it's uh it's sometimes 260 00:15:34,960 --> 00:15:37,760 Speaker 1: called the gold standard in terms of infertility because of 261 00:15:37,760 --> 00:15:40,920 Speaker 1: the way it does stimulate simulate the follical growth and 262 00:15:40,960 --> 00:15:44,000 Speaker 1: the ovulation. But I think it's important to note that 263 00:15:44,080 --> 00:15:47,200 Speaker 1: even though, but I think it's important to note that 264 00:15:47,320 --> 00:15:52,240 Speaker 1: even beyond the infertility problems, you can have problems with pregnancy. 265 00:15:52,280 --> 00:15:54,840 Speaker 1: If you've had peaks, you might have early pregnancy loss, 266 00:15:54,880 --> 00:16:00,120 Speaker 1: just gestational diabetes, pregnancy induced hype blood pressure, pre acclaim 267 00:16:00,000 --> 00:16:02,440 Speaker 1: and sees. So it's a huge problem for women who 268 00:16:02,520 --> 00:16:05,680 Speaker 1: are trying to have children. UM, So that's sort of 269 00:16:05,720 --> 00:16:09,640 Speaker 1: the side side road into fertility. But I also wanted 270 00:16:09,640 --> 00:16:12,560 Speaker 1: to say that because of all these problems with insulin 271 00:16:12,600 --> 00:16:15,440 Speaker 1: that are related to PEAK hosts, sometimes they might prescribe 272 00:16:15,440 --> 00:16:19,080 Speaker 1: you with insulin sensitizing medications or they might just you know, 273 00:16:19,200 --> 00:16:23,920 Speaker 1: put you on regular exercise and low carb diet. You know, obviously, 274 00:16:23,960 --> 00:16:26,920 Speaker 1: if you are risker diabeteses are things that a doctor 275 00:16:26,920 --> 00:16:29,400 Speaker 1: would put you on anyway. But you know, it seems 276 00:16:29,400 --> 00:16:32,200 Speaker 1: like when it was birth control plus this insulin thing. 277 00:16:32,200 --> 00:16:35,360 Speaker 1: It's very a symptomatic approach to this. There is no 278 00:16:35,480 --> 00:16:37,760 Speaker 1: sort of, as Kristen said, overall cure. You're going to 279 00:16:37,840 --> 00:16:40,840 Speaker 1: be sort of treating symptom by symptom because you know, 280 00:16:40,880 --> 00:16:43,800 Speaker 1: they don't really know what's causing this. They don't know 281 00:16:44,320 --> 00:16:46,920 Speaker 1: um what exactly they're trying to go after to stop 282 00:16:46,960 --> 00:16:49,600 Speaker 1: it from happening or to stop it from progressing. It's 283 00:16:49,680 --> 00:16:52,120 Speaker 1: very much like, Okay, now we're gonna deal with the 284 00:16:52,200 --> 00:16:55,000 Speaker 1: regular menstrual cycle cycles. Now we'll deal with the weight. 285 00:16:55,040 --> 00:16:57,200 Speaker 1: Now we'll deal with the act anything. But the good 286 00:16:57,200 --> 00:17:00,880 Speaker 1: news is in terms of peak hoast is, in recent 287 00:17:01,040 --> 00:17:03,600 Speaker 1: years it really has started to get a lot more 288 00:17:03,600 --> 00:17:07,440 Speaker 1: attention within the medical field. For instance, uh in two 289 00:17:07,480 --> 00:17:11,000 Speaker 1: thousand and six there was a huge medical seminar in 290 00:17:11,080 --> 00:17:15,720 Speaker 1: which a couple of doctors estimated that it affects one 291 00:17:15,760 --> 00:17:20,119 Speaker 1: in fifteen women worldwide, and they really called attention to 292 00:17:20,800 --> 00:17:24,399 Speaker 1: um this issue, not just in terms of it affecting 293 00:17:24,400 --> 00:17:27,080 Speaker 1: the health of women, especially like in westernized nations. I 294 00:17:27,080 --> 00:17:29,680 Speaker 1: think that when we think about, um, women's health care, 295 00:17:29,720 --> 00:17:32,520 Speaker 1: we can tend to have a very Western view of that. Okay, 296 00:17:32,560 --> 00:17:35,240 Speaker 1: I've got I'm having all these symptoms. I'm going to 297 00:17:35,359 --> 00:17:37,919 Speaker 1: go to my guy no and get on meds and 298 00:17:37,920 --> 00:17:41,080 Speaker 1: it's going to be totally kosher. That's not really the 299 00:17:41,119 --> 00:17:44,680 Speaker 1: case worldwide. UM. If you think about happening to one 300 00:17:44,680 --> 00:17:51,040 Speaker 1: in fifteen women, it's a major economic health burden as well, UM, 301 00:17:51,080 --> 00:17:53,639 Speaker 1: just because of the wide range of symptoms that it 302 00:17:53,680 --> 00:17:56,679 Speaker 1: can have, especially in places where this kind of medical 303 00:17:56,680 --> 00:18:00,760 Speaker 1: assistance is not going to be as available for these women. 304 00:18:00,840 --> 00:18:06,040 Speaker 1: So doctors have really tried to dig into finding the 305 00:18:06,200 --> 00:18:09,440 Speaker 1: root cause of pcos and there have been some studies 306 00:18:09,440 --> 00:18:12,359 Speaker 1: that Molly and I've found that are starting to get 307 00:18:12,400 --> 00:18:17,920 Speaker 1: a clearer understanding of where picos come from comes from, 308 00:18:18,119 --> 00:18:23,600 Speaker 1: its linked to obesity in particular, and genetics involved. Right, 309 00:18:23,680 --> 00:18:26,000 Speaker 1: Let's start with one study from two thousand nine. It 310 00:18:26,119 --> 00:18:30,960 Speaker 1: found that there was this gene that's implicated in obesity 311 00:18:31,000 --> 00:18:34,680 Speaker 1: that might be associated with susceptibility to polycystic overa syndrome 312 00:18:35,040 --> 00:18:38,600 Speaker 1: and carriers of one gene, the ft O gene. Uh, 313 00:18:38,640 --> 00:18:41,320 Speaker 1: It's not only influenced whether the person became obese, but 314 00:18:41,400 --> 00:18:44,600 Speaker 1: also whether they developed the other symptoms related to PICOS. 315 00:18:44,680 --> 00:18:47,439 Speaker 1: And one thing we should say is that it is 316 00:18:47,560 --> 00:18:52,000 Speaker 1: possible it's not as common for men to get PICOS 317 00:18:52,359 --> 00:18:56,440 Speaker 1: because if there is this genetic component, then uh, if 318 00:18:56,480 --> 00:18:58,679 Speaker 1: you know, if your mother or sister has it, then 319 00:18:58,720 --> 00:19:00,840 Speaker 1: you are at risk for also having this gene. So 320 00:19:00,880 --> 00:19:03,359 Speaker 1: they're trying to find out more about that. But in 321 00:19:03,400 --> 00:19:05,399 Speaker 1: two thousand ten there was another study that sort of 322 00:19:05,440 --> 00:19:08,600 Speaker 1: looked at how fat tissue was handled in someone who 323 00:19:08,880 --> 00:19:11,920 Speaker 1: had PICOS and it acts differently, so there's something there's 324 00:19:11,920 --> 00:19:13,520 Speaker 1: some gene. They're still trying to figure out what it 325 00:19:13,600 --> 00:19:16,920 Speaker 1: is that affects how your fat is stored, how it's 326 00:19:16,960 --> 00:19:20,080 Speaker 1: acting within the body, and how it could possibly then 327 00:19:20,080 --> 00:19:23,360 Speaker 1: trigger these problems with the pituitary gland and the hormones 328 00:19:23,400 --> 00:19:29,199 Speaker 1: related to reproduction. Researchers from the London Women's Clinic analyzed 329 00:19:29,880 --> 00:19:33,560 Speaker 1: six eighteen women who attended the clinic for fertility treatment 330 00:19:34,240 --> 00:19:39,440 Speaker 1: over two years okay, and they found that eighty percent 331 00:19:39,840 --> 00:19:43,520 Speaker 1: of the lesbian women who were involved in the study 332 00:19:43,960 --> 00:19:51,000 Speaker 1: had polycystic ovaries, compared to only thirty in heterosexual women. 333 00:19:51,240 --> 00:19:55,000 Speaker 1: Lesbian women also had higher rates of PICOS with thirty 334 00:19:55,040 --> 00:19:59,520 Speaker 1: eight percent having the syndrome compared to fourteen percent of 335 00:19:59,640 --> 00:20:05,600 Speaker 1: hetero sexual women. That suggests some kind of biological, hormonal 336 00:20:05,680 --> 00:20:10,960 Speaker 1: underlying link to sexuality, which could then possibly be linked 337 00:20:11,000 --> 00:20:14,480 Speaker 1: to genetics. So that was the study was significant just 338 00:20:14,480 --> 00:20:17,600 Speaker 1: because it linked for the first time so concretely that 339 00:20:17,760 --> 00:20:21,800 Speaker 1: hormonal makeup, that genetic makeup with sexual orientation. So for 340 00:20:21,840 --> 00:20:24,639 Speaker 1: those people who still argue that it's a choice that 341 00:20:24,760 --> 00:20:27,600 Speaker 1: these you know that everyone can be straight if they 342 00:20:27,600 --> 00:20:31,359 Speaker 1: want to, it's another brick in the wall that there's 343 00:20:31,400 --> 00:20:35,159 Speaker 1: a genetic reason for for sexual orientation, right, and perhaps 344 00:20:35,200 --> 00:20:38,480 Speaker 1: a higher incidents rated picos Not the most pleasant link 345 00:20:38,720 --> 00:20:42,240 Speaker 1: in the world, um, but a link all the same. Yeah, 346 00:20:42,280 --> 00:20:45,680 Speaker 1: and we felt like it was definitely worth highlighting. Now, finally, 347 00:20:45,720 --> 00:20:48,040 Speaker 1: we've been talking a lot about genes, but there is also, 348 00:20:48,080 --> 00:20:50,560 Speaker 1: as I mentioned a little bit earlier in the podcasts, 349 00:20:50,600 --> 00:20:54,800 Speaker 1: the idea that there could be an environmental influence to 350 00:20:55,240 --> 00:21:00,479 Speaker 1: picos and specifically, UM, this chemical that is containing a 351 00:21:00,480 --> 00:21:04,080 Speaker 1: lot of plastics, although it is being gradually phased out. UH, 352 00:21:04,320 --> 00:21:08,760 Speaker 1: this chemical bisphenol A or b p A. If you 353 00:21:08,800 --> 00:21:11,680 Speaker 1: don't want to give it the Grand the Grand pronouncement 354 00:21:11,720 --> 00:21:15,320 Speaker 1: that Kristen did and uh b p A amazingly. It 355 00:21:15,440 --> 00:21:18,240 Speaker 1: just it creates this really vicious cycle in women who 356 00:21:18,320 --> 00:21:21,480 Speaker 1: are susceptible to peak host because once you have peaks, 357 00:21:21,680 --> 00:21:25,359 Speaker 1: then you are more uh then uh b p A 358 00:21:25,400 --> 00:21:27,879 Speaker 1: has an easier time kind of steeping into your bloodstream 359 00:21:27,920 --> 00:21:31,960 Speaker 1: and causing reproductive damage. But then again, you're already having 360 00:21:32,359 --> 00:21:35,199 Speaker 1: reproductive problems. Your hormones are already out of whack, so 361 00:21:35,240 --> 00:21:37,760 Speaker 1: then b p A can kind of heighten that as well. 362 00:21:38,240 --> 00:21:41,000 Speaker 1: And so not only are you more susceptible to it, 363 00:21:41,480 --> 00:21:43,800 Speaker 1: you're going to have greater problems from It's just cycle 364 00:21:43,840 --> 00:21:47,520 Speaker 1: after cycle because BP has been b p A has 365 00:21:47,560 --> 00:21:50,720 Speaker 1: been shown to be an endocrine disruptor. So yeah, it's 366 00:21:50,720 --> 00:21:57,399 Speaker 1: just like throwing um, yes fuel chemical fuel on the fire. 367 00:21:57,880 --> 00:22:00,320 Speaker 1: It's true, that's my phrase today, I fuel on the fire. 368 00:22:00,760 --> 00:22:04,760 Speaker 1: So that is an overview of picos. Obviously, for the 369 00:22:04,800 --> 00:22:07,120 Speaker 1: women out there who are listening to this, who are 370 00:22:07,240 --> 00:22:11,680 Speaker 1: dealing with picos, it probably seems like an incredibly oversimplified 371 00:22:11,800 --> 00:22:14,000 Speaker 1: version of it because living with it day to day, 372 00:22:14,240 --> 00:22:18,080 Speaker 1: from what we've read, seems like quite a task. Um 373 00:22:18,119 --> 00:22:21,360 Speaker 1: and even getting it diagnosed in the first place can 374 00:22:21,400 --> 00:22:24,400 Speaker 1: behalf the battle, right, And like we said at the beginning, 375 00:22:24,560 --> 00:22:27,679 Speaker 1: I think that this podcast really encapsulates a lot of 376 00:22:27,680 --> 00:22:30,359 Speaker 1: things we've talked about. So if you've ever heard a 377 00:22:30,359 --> 00:22:33,120 Speaker 1: podcast about, you know, women's attachment to hair or why 378 00:22:33,160 --> 00:22:36,040 Speaker 1: women don't want facial hair, then just sort of magnify 379 00:22:36,160 --> 00:22:38,760 Speaker 1: it by you know, a million in terms of what 380 00:22:38,800 --> 00:22:42,359 Speaker 1: you'd be dealing with with this um condition. But I 381 00:22:42,400 --> 00:22:45,040 Speaker 1: would hope that what Chris and I always try and 382 00:22:45,040 --> 00:22:48,320 Speaker 1: do is just open up conversations and try and less 383 00:22:48,320 --> 00:22:50,840 Speaker 1: than stigma around some of these symptoms. So if you 384 00:22:51,600 --> 00:22:54,480 Speaker 1: are living with a lot of shame, depression, pain just 385 00:22:54,520 --> 00:22:57,080 Speaker 1: because you don't know how to approach a doctor about 386 00:22:57,160 --> 00:23:00,320 Speaker 1: any one of these problems issues within fertility, and there's 387 00:23:00,400 --> 00:23:03,600 Speaker 1: so many, so many factors associated with us, just try 388 00:23:03,600 --> 00:23:07,720 Speaker 1: and take the confidence to uh, just try and build 389 00:23:07,760 --> 00:23:10,480 Speaker 1: it up. It's hard to try and get medical help. 390 00:23:10,520 --> 00:23:12,320 Speaker 1: And when you have to see those four doctors in 391 00:23:12,359 --> 00:23:15,639 Speaker 1: a row, be persistent and know that you know you 392 00:23:15,680 --> 00:23:18,159 Speaker 1: know when something's wrong with your body and and you 393 00:23:18,200 --> 00:23:22,160 Speaker 1: need to fight for your diagnosis of that absolutely. So 394 00:23:23,000 --> 00:23:26,840 Speaker 1: in the meantime, if you would like to share your 395 00:23:27,160 --> 00:23:30,280 Speaker 1: story of Pico's story with Molly me our email addresses 396 00:23:30,280 --> 00:23:32,879 Speaker 1: mom stuff at house stuff works dot com, or share 397 00:23:32,920 --> 00:23:36,119 Speaker 1: it with all of our listeners on our Facebook page. 398 00:23:36,640 --> 00:23:42,320 Speaker 1: In the meantime, let's read a couple of those listener emails. Actually, 399 00:23:42,359 --> 00:23:44,439 Speaker 1: this one was a listener snail mail, and you can 400 00:23:44,480 --> 00:23:46,720 Speaker 1: find our snail mail address on the website how stuff 401 00:23:46,720 --> 00:23:50,240 Speaker 1: works dot com. And this is from Helena, who also 402 00:23:50,320 --> 00:23:54,800 Speaker 1: sent us brownies. They were delicious and muffins her but 403 00:23:54,880 --> 00:23:56,760 Speaker 1: you were the one who requested brownies in a recent 404 00:23:56,800 --> 00:23:59,679 Speaker 1: podcast Christen and Molly and I Love Baked Goods. She 405 00:23:59,800 --> 00:24:02,520 Speaker 1: took us up on it um and but she included 406 00:24:02,560 --> 00:24:05,600 Speaker 1: this email that was response to the podcast about men 407 00:24:05,640 --> 00:24:09,480 Speaker 1: and women cooking differently, and she writes, You're entirely right 408 00:24:09,480 --> 00:24:12,360 Speaker 1: in your observation that there's an underlying gendering of cooking. 409 00:24:12,840 --> 00:24:15,560 Speaker 1: This gendering, however evident in the public workplace, is equally 410 00:24:15,560 --> 00:24:17,879 Speaker 1: as evident in the domestic one. Let me use myself 411 00:24:17,920 --> 00:24:21,040 Speaker 1: as an example. For me, cooking is a creative process, 412 00:24:21,080 --> 00:24:23,040 Speaker 1: a stress reliever, and something I've loved since I was 413 00:24:23,040 --> 00:24:25,280 Speaker 1: a little kid. Growing up, I thought I would either 414 00:24:25,280 --> 00:24:27,520 Speaker 1: be one of two things, a writer or a cook. 415 00:24:27,840 --> 00:24:29,840 Speaker 1: But as I grew older, I realized quickly that working 416 00:24:29,840 --> 00:24:31,879 Speaker 1: in the service industry might would not offer me the 417 00:24:31,920 --> 00:24:35,199 Speaker 1: same satisfying experiences as cooking at home for family and 418 00:24:35,280 --> 00:24:38,240 Speaker 1: friends might. If I cooked for a profession, then I 419 00:24:38,240 --> 00:24:40,320 Speaker 1: would never really lose all passion for it, and I 420 00:24:40,480 --> 00:24:43,600 Speaker 1: never wanted to jeopardize my enthusiasm for being in the kitchen. 421 00:24:44,480 --> 00:24:46,520 Speaker 1: So she writes about how she made that decision to 422 00:24:46,960 --> 00:24:49,680 Speaker 1: you know, not not going to cooking professionally, send to 423 00:24:49,680 --> 00:24:52,639 Speaker 1: another field. But in two thousand nine, she writes, I 424 00:24:52,680 --> 00:24:56,240 Speaker 1: started a food cooking and recipe blog, and the address 425 00:24:56,280 --> 00:25:00,080 Speaker 1: of that is clearly delicious food blog dot com. And 426 00:25:00,080 --> 00:25:03,040 Speaker 1: Helena goes on to write, as an academic, I find 427 00:25:03,040 --> 00:25:05,399 Speaker 1: food blogging to be a wonderful source of creative writing 428 00:25:05,640 --> 00:25:09,639 Speaker 1: while also indulging in one of my favorite hobbies. And uh, 429 00:25:09,880 --> 00:25:12,000 Speaker 1: she writes about how food blogging is it a credible 430 00:25:12,119 --> 00:25:15,280 Speaker 1: community for women, which is pretty interesting and probably its 431 00:25:15,280 --> 00:25:18,479 Speaker 1: own podcast topic, and then she writes to summarize, perhaps 432 00:25:18,480 --> 00:25:20,160 Speaker 1: then the question is not do you men or women 433 00:25:20,160 --> 00:25:22,840 Speaker 1: cook differently? But where do you men or women cook? 434 00:25:22,920 --> 00:25:25,480 Speaker 1: And how is that different? And that very possibly the 435 00:25:25,560 --> 00:25:28,320 Speaker 1: answer to your two questions cooking at Homer as a 436 00:25:28,359 --> 00:25:31,359 Speaker 1: creative outlet allows many women to strengthen the divide between 437 00:25:31,400 --> 00:25:34,360 Speaker 1: work and home. For me and many other food bloggers, 438 00:25:34,359 --> 00:25:36,960 Speaker 1: we can have our cake and eat it too. Thank 439 00:25:37,000 --> 00:25:40,399 Speaker 1: you so much, Helena, and yeah again, many things for 440 00:25:40,440 --> 00:25:43,040 Speaker 1: those brownies and mohn. All right, well the closings out. 441 00:25:43,040 --> 00:25:44,919 Speaker 1: I've got an email here from Paul and this was 442 00:25:45,040 --> 00:25:49,600 Speaker 1: in relation to our podcast about pain of size. Uh, 443 00:25:49,640 --> 00:25:52,679 Speaker 1: he says, Uh. It reminded me of a saying a 444 00:25:52,680 --> 00:25:55,919 Speaker 1: girl I once knew who said men care about the 445 00:25:55,960 --> 00:25:59,240 Speaker 1: penis attached to the guy. Women care about the guy 446 00:25:59,280 --> 00:26:01,719 Speaker 1: attached to the penis. I don't know why, but I've 447 00:26:01,720 --> 00:26:04,200 Speaker 1: always remembered that he said. He mentioned women in their 448 00:26:04,200 --> 00:26:06,439 Speaker 1: weight several times towards the end of the podcast, so 449 00:26:06,480 --> 00:26:10,000 Speaker 1: I throught so I thought i'd throw this in. Speaking 450 00:26:10,000 --> 00:26:11,960 Speaker 1: as a guy, I can tell you that guys honestly 451 00:26:12,000 --> 00:26:15,400 Speaker 1: don't care about a girl's weight. In general, guys each 452 00:26:15,400 --> 00:26:17,720 Speaker 1: have their own types weight wise, and they generally don't 453 00:26:17,720 --> 00:26:20,919 Speaker 1: even bother dating women who aren't in the category. So 454 00:26:20,960 --> 00:26:23,120 Speaker 1: if a guys into a girl, he's into the girl 455 00:26:23,240 --> 00:26:25,680 Speaker 1: as she is. He doesn't care about weight at all, 456 00:26:25,760 --> 00:26:28,600 Speaker 1: And it's a totally non issue and my way, we 457 00:26:28,640 --> 00:26:33,320 Speaker 1: have gotten so many interesting responses about this penis episode 458 00:26:33,400 --> 00:26:36,639 Speaker 1: from our male listeners, and um, very few of you 459 00:26:36,680 --> 00:26:39,520 Speaker 1: guys believe that size doesn't matter. So Molly, we might 460 00:26:39,560 --> 00:26:41,439 Speaker 1: just have to have a follow up and let the 461 00:26:41,480 --> 00:26:44,760 Speaker 1: men speak in response to their anatomy that when I 462 00:26:44,800 --> 00:26:48,800 Speaker 1: don't share. Um, And they were the exact emails that 463 00:26:48,840 --> 00:26:51,399 Speaker 1: I was hoping to get, because I was really hoping 464 00:26:51,440 --> 00:26:56,080 Speaker 1: to uh to provoke some some thoughts and responses and 465 00:26:56,200 --> 00:26:59,879 Speaker 1: keep them coming men and women. Of course, our email 466 00:27:00,080 --> 00:27:03,119 Speaker 1: mom stuff at how stuff works dot com. Find us 467 00:27:03,160 --> 00:27:05,920 Speaker 1: on Facebook where it Stuff Monever told You, follow us 468 00:27:05,920 --> 00:27:08,440 Speaker 1: on Twitter. I can really just engage us in every 469 00:27:08,520 --> 00:27:12,120 Speaker 1: aspect of your life. That's what Molly and I want, uh, 470 00:27:12,160 --> 00:27:14,560 Speaker 1: And during the week read what we have to say 471 00:27:15,000 --> 00:27:17,680 Speaker 1: with words on a page. It's the Stuff Monever Told 472 00:27:17,680 --> 00:27:29,119 Speaker 1: You blog and it's at how stuff works dot com. 473 00:27:29,359 --> 00:27:32,119 Speaker 1: Want more how stuff works, check out our blogs on 474 00:27:32,200 --> 00:27:39,040 Speaker 1: the house stuff works dot com home page. Brought to 475 00:27:39,080 --> 00:27:42,159 Speaker 1: you by the reinvented two thousand twelve camera. It's ready, 476 00:27:42,359 --> 00:27:42,800 Speaker 1: are you