WEBVTT - Waze Co-Founder Sees a Resilient Israeli Tech Scene

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<v Speaker 1>This is Bloomberg Business Wait inside from the reporters and

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<v Speaker 1>editors who bring you America's most trusted business magazine, plus

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<v Speaker 1>global business finance and tech news. The Bloomberg Business Week

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<v Speaker 1>Podcast with Carol Messer and Tim Stenebeck from Bloomberg Radio.

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<v Speaker 2>All Right, everybody, to say that a lot has happened

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<v Speaker 2>since we last checked in with our next guest would

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<v Speaker 2>be an understatement.

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<v Speaker 3>Big time.

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<v Speaker 2>Or Levine last joined us earlier this year, before the

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<v Speaker 2>October seventh Hamas attack on Israel. Or as you know,

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<v Speaker 2>Many is the co founder, of course, of the navigation

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<v Speaker 2>app Ways, which Google bought for more than one point

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<v Speaker 2>one billion dollars. Who's also an investor in move It,

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<v Speaker 2>which then Tim Intel bought for a billion dollars.

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<v Speaker 4>Well I spoke to him because of his new book,

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<v Speaker 4>fall in Love with the Problem, Not the Solution, a

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<v Speaker 4>handbook for entrepreneurs. It details his journey and also his

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<v Speaker 4>unique philosophy on what it takes to be a successful innovator.

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<v Speaker 4>He's a graduate from the Tel Aviv University and served

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<v Speaker 4>in the Israeli Army Special Intelligence Unit. He started both

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<v Speaker 4>Ways and moved companies in Israel, which of course is

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<v Speaker 4>currently at war with Hamas in the Gaza strip or

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<v Speaker 4>good to have you back here in the Bloomberg Interactive

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<v Speaker 4>Brokers studio. How are you doing?

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<v Speaker 5>You know, it's complicated, right, because it's never going to

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<v Speaker 5>be the same. It's never going to be the same.

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<v Speaker 5>That was a devastating attack. That was you know, my

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<v Speaker 5>kids are the age between twenty two and thirty three.

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<v Speaker 5>They could have been at this party, and there were

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<v Speaker 5>many days that that was my main thought of the day,

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<v Speaker 5>that I'm lucky that they weren't. That was devastating. And

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<v Speaker 5>I think that at the end of the day, if

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<v Speaker 5>you look into the future or you realize that they

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<v Speaker 5>might be a solution, but without Hamas being.

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<v Speaker 2>There, Well that's what we think about. We talk a

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<v Speaker 2>lot about the way forward. I've talked to people I

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<v Speaker 2>feel like on both sides, and when I say sides,

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<v Speaker 2>I don't mean on Hamas's side, but I mean on

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<v Speaker 2>the Palestinian point of view, the Israeli point of view,

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<v Speaker 2>about how do we go forward? How do we stop

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<v Speaker 2>that we don't find five years from now, ten years

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<v Speaker 2>we're still talking about conflict in that region. How do

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<v Speaker 2>you think about that?

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<v Speaker 5>So look at the end of the day, if you

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<v Speaker 5>think about the Palestinians and Gaza strip and you ask

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<v Speaker 5>yourself whether or not Tramas was doing any good for them.

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<v Speaker 5>Not really, they were doing very good for themselves, but

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<v Speaker 5>not for the people. And look, Israel left the Gaza

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<v Speaker 5>Striep some seventeen eighteen years ago. There was an opportunity

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<v Speaker 5>to build awesome ness there and Ramas to go over.

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<v Speaker 5>And basically this is a terrorist organization, right They're only

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<v Speaker 5>agenda that they have is to kill us, and that

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<v Speaker 5>doesn't work. We guess what we don't want to be

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<v Speaker 5>to get killed?

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<v Speaker 2>Can I ask you? And I feel like this is

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<v Speaker 2>such a difficult conversation. We've had a lot of times

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<v Speaker 2>in the newsroom. Tim and I've talked a lot of

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<v Speaker 2>times after a show or after a guest. You know

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<v Speaker 2>this concept. I get it of having to fight back,

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<v Speaker 2>but this concept of killing and then more killing, and

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<v Speaker 2>it's just like where does it stop or how does

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<v Speaker 2>it stop? And how do you justify that on both sides?

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<v Speaker 2>I understand.

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<v Speaker 5>I So, number one, you know, I'm not the Prime minister.

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<v Speaker 5>It's not for me that needs to make those decisions.

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<v Speaker 5>But at the end of the day, if you realize

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<v Speaker 5>that if Ramas is being removed from the region, then

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<v Speaker 5>there are opportunities for something else completely different, right, because

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<v Speaker 5>at the end of the day, most people prefair leaving

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<v Speaker 5>over dying, right, And most of the people in the

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<v Speaker 5>Gaza Strip it's the same for them. The challenge is

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<v Speaker 5>that the leadership of the Haramas is the one that

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<v Speaker 5>is basically enjoying the killing on one hand and the

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<v Speaker 5>power in particular that they have. And I think that

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<v Speaker 5>once they are being removed, there is an opportunity and

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<v Speaker 5>I see major role of the US, major role of

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<v Speaker 5>Saudi Arabia helping to recreate something new in the Middle East.

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<v Speaker 4>Well, talk a little bit about that, because that's a

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<v Speaker 4>part of the equation that I'm having trouble seeing here

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<v Speaker 4>the solution and what actually happens. And it sounds like

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<v Speaker 4>you think Hamas can be removed from power. So let's

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<v Speaker 4>say Hamas is successfully removed from power in the Gaza Strip,

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<v Speaker 4>what would you like to see happened?

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<v Speaker 5>So again we have to realize that what I would

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<v Speaker 5>like to see has I have zero influence on that,

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<v Speaker 5>or maybe a little bit of influence, but that's about it.

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<v Speaker 5>But I think that the opportunity here is that really

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<v Speaker 5>recreating something new with the support of the American with

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<v Speaker 5>the support of the Saudis, and basically establishing sort of

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<v Speaker 5>normalizations in the relationship. Right now, if you look at

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<v Speaker 5>the history of Israel, every time there was a major crisis,

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<v Speaker 5>two things happened. Number one as well grew up stronger.

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<v Speaker 5>Number two, we actually figure out a way, a different way, right.

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<v Speaker 5>That's true for the Yong Kipoor War back in the

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<v Speaker 5>seventy three, and after that we had a piece with Egypt, right,

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<v Speaker 5>And that's true for World War Two where the Holocaust happened,

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<v Speaker 5>and after that there was a Jewish statement. And so

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<v Speaker 5>at the end of the day, I think that October

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<v Speaker 5>seventh is such a major crisis that it will lead

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<v Speaker 5>into something else, and you know, hopefully as soon as possible. Right,

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<v Speaker 5>But when is that going to happen?

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<v Speaker 6>We don't know, do you believe?

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<v Speaker 2>I mean, you work with individuals in Palestine or in

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<v Speaker 2>the Strip, in.

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<v Speaker 5>God Strip, not specifically, but with you know, otter nations

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<v Speaker 5>in the region.

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<v Speaker 2>Yes, What I guess what I'm curious about is why

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<v Speaker 2>we haven't been able to figure out a two state

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<v Speaker 2>solution up to this point.

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<v Speaker 5>I would say that you have to ask the leadership

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<v Speaker 5>that I think that at the end of the day.

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<v Speaker 2>But is that a solution? You're smart man, you actually

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<v Speaker 2>think out of the box.

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<v Speaker 5>Obviously it is right at the end of the day. Well,

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<v Speaker 5>Hamas really created severe porn poor people in the Gaza

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<v Speaker 5>strip right now, when you are poor and you have

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<v Speaker 5>no hope, you have nothing to lose, right if you

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<v Speaker 5>create something else, If people have something to lose, then

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<v Speaker 5>they would prefer peace over war time after time in

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<v Speaker 5>the history. When people have something to lose, then they

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<v Speaker 5>actually prefer the stability rather than the instability. And in

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<v Speaker 5>many cases this is you know, the craziness of the

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<v Speaker 5>leadership that leads into acts of war. Right, so we

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<v Speaker 5>can see the same thing with Russia and Ukraine, and

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<v Speaker 5>we have seen that throughout many cases in Europe, in

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<v Speaker 5>the Middle East, in other places.

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<v Speaker 2>So what do you think of when people will say

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<v Speaker 2>you talk about Russian and Ukraine and tim and I.

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<v Speaker 2>You know, we've had a lot of discussions with individuals

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<v Speaker 2>this idea that we are so opposed to the Russian

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<v Speaker 2>occupation of Ukraine, and then people say, well, why aren't

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<v Speaker 2>you similarly upset about the Israel Israeli occupation of Gaza.

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<v Speaker 5>Israelis not occupying Gaza, and Gazza is a free place

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<v Speaker 5>for the last Israel withdrawn from Gaza strip some seventeen

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<v Speaker 5>or eighteen years ago.

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<v Speaker 6>We are not occupying Gaza. Kamasi is occupying Gaza.

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<v Speaker 4>What would you say is the prevailing view within your

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<v Speaker 4>social circle about the way this ends?

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<v Speaker 6>Sorry? Can you repeople?

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<v Speaker 4>Yeah, what's the conversation that you're having with your fellow entrepreneurs,

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<v Speaker 4>with your friends, with your family right now about the

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<v Speaker 4>way this ends?

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<v Speaker 5>So, in general, I would say tough time creates stronger people.

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<v Speaker 5>Stronger people then creates better times, right than ISRAELI is

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<v Speaker 5>in under tough time right now. Entrepreneurs are going to

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<v Speaker 5>be the first one to recover and they will be

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<v Speaker 5>recovering strongly and better after that, because what happened during

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<v Speaker 5>war is that the forget all the horror things that happens.

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<v Speaker 6>In the war. After the war, people are way.

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<v Speaker 5>Stronger and they realize that there is a defense choice

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<v Speaker 5>for them, which is leaving, and they realize that now

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<v Speaker 5>if they survive, that they can survive anything.

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<v Speaker 4>We're pleased to add back with us Ory Levine to

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<v Speaker 4>continue our conversation as many of you know. He's the

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<v Speaker 4>co founder of the navigation app Ways. Google bought it

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<v Speaker 4>for more than at one point one billion dollars more

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<v Speaker 4>than a decade ago at this point, also an investor

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<v Speaker 4>and move It, which Intel bought for a billion dollars.

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<v Speaker 4>We're going to get to how he's thinking about startups

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<v Speaker 4>right now, especially in Israel where he built these two companies,

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<v Speaker 4>in just a second. But I do want to continue

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<v Speaker 4>the conversation that we're having earlier about the environment there.

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<v Speaker 4>Right now, in the wake of the October seventh attack

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<v Speaker 4>from Hamas, I want to talk economy a little bit

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<v Speaker 4>because I don't think people understand that when people get

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<v Speaker 4>called back to the military, they leave their jobs to

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<v Speaker 4>go back to the Israeli military. So there's a whole

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<v Speaker 4>element of the Israeli economy that's not working the way

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<v Speaker 4>that it should right now.

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<v Speaker 6>Are you seeing the.

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<v Speaker 4>Effects of that day to day that there is a

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<v Speaker 4>shortage of workers, that there are a lot of people

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<v Speaker 4>who I mean, I have friends on Facebook who've posted

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<v Speaker 4>Israelis who've said, you know, my husband is away fighting

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<v Speaker 4>right now because he got called back. She's a tour

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<v Speaker 4>operator who does restaurant tours, for tourists. There's no tourists

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<v Speaker 4>there right now, so she literally they literally have no

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<v Speaker 4>income coming in right now as a result of this.

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<v Speaker 5>So not exactly, because when you're doing your military or reserve,

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<v Speaker 5>you do get from the Social security the same pay

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<v Speaker 5>at you what gotlin if you were working. But if

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<v Speaker 5>you look at the impact of them war on the economy,

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<v Speaker 5>then I would say, for a second, obviously budget for

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<v Speaker 5>security and is going to go up dramatic. Then that's

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<v Speaker 5>we all realize the war costs money some markets, some

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<v Speaker 5>industries are completely suffering from that, right like tourism right

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<v Speaker 5>there is there there are no tourists going to Israel,

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<v Speaker 5>right And I don't blame them, right they shouldn't. It's

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<v Speaker 5>there is a war there and they don't feel safe.

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<v Speaker 6>And that's all.

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<v Speaker 5>High tech industry is actually getting stronger because what we

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<v Speaker 5>are realizing is that the people that are still there,

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<v Speaker 5>they are carrying the load for all the people that

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<v Speaker 5>are going on the military or reserve and so forth.

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<v Speaker 5>And what we have seen is that the productivity increased dramatically.

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<v Speaker 5>And when people that will be coming back from the

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<v Speaker 5>military reserve, then we are likely to see.

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<v Speaker 6>Huge growth in the high tech.

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<v Speaker 5>In general, the challenge right now for the high time,

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<v Speaker 5>the Israeli high tech, that it's harder to raise capital, right,

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<v Speaker 5>so most of the investors will prefer to be.

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<v Speaker 6>On the fence.

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<v Speaker 5>And and you know, way to see that the war

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<v Speaker 5>is over, right, investing in a war zone people afraid,

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<v Speaker 5>and they rightly.

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<v Speaker 4>So that's interesting to hear because you've also got a

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<v Speaker 4>group of very vocal Americans who are happy to give

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<v Speaker 4>to Israeli causes. And I would think that some of

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<v Speaker 4>those would be supportive of a venture capital. Of course,

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<v Speaker 4>they in the country, they to kind of help prop

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<v Speaker 4>it up the time.

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<v Speaker 6>They do, and they will.

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<v Speaker 5>But in general, if you look at the you know,

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<v Speaker 5>non Jewish investors or non engaged investors, then they have

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<v Speaker 5>more challenging time, not all of.

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<v Speaker 6>Them, but a lot.

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<v Speaker 2>Or is there anything you've put on hold because that's

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<v Speaker 2>home base for you, correct Israel?

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<v Speaker 5>Or so why you know I keep on building. Look,

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<v Speaker 5>I have a very simple life. I have a mission,

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<v Speaker 5>I have a destiny, I have a purpose and this

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<v Speaker 5>is about value creation, right, and then I can create

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<v Speaker 5>value through multiple ways, through you know, building startups that

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<v Speaker 5>help people, through you know, coaching and mentoring, a group

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<v Speaker 5>of CEOs that of my startups through teaching and through

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<v Speaker 5>you know, the ultimate way of teaching is the book itself.

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<v Speaker 5>They're falling up with the problem, not the solution. Book

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<v Speaker 5>is by and large it This is sharing my know

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<v Speaker 5>how with people and hopefully make them more successful.

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<v Speaker 4>What's the problem that you see right now that needs

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<v Speaker 4>to be working.

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<v Speaker 6>Exactly? Take a pick.

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<v Speaker 5>So the good news is that there are a lot

0:12:37.040 --> 0:12:39.079
<v Speaker 5>of problems. The bad news is that there are a

0:12:39.120 --> 0:12:40.880
<v Speaker 5>lot of problems right end of the day, there are

0:12:40.880 --> 0:12:43.960
<v Speaker 5>a lot of problems. One of the you know, major

0:12:44.040 --> 0:12:46.640
<v Speaker 5>problems that we are addressing recently is actually in the

0:12:46.760 --> 0:12:50.600
<v Speaker 5>US the realization that most people will not have enough

0:12:50.800 --> 0:12:54.720
<v Speaker 5>saving for retirement. And so Pontera is one of the

0:12:54.720 --> 0:12:57.760
<v Speaker 5>companies that is helping that in the US help people

0:12:57.800 --> 0:13:03.520
<v Speaker 5>to eventually retire richer. And so this is and this

0:13:03.600 --> 0:13:05.200
<v Speaker 5>is a big problem at the end of the day

0:13:05.600 --> 0:13:07.920
<v Speaker 5>when people get old and they don't have enough money.

0:13:07.960 --> 0:13:10.840
<v Speaker 5>This is a big problem. So this is one of

0:13:10.880 --> 0:13:13.360
<v Speaker 5>the things that I'm trying to do with my startups.

0:13:14.840 --> 0:13:19.920
<v Speaker 5>And you know, dealing with parking. Parking is a major

0:13:19.960 --> 0:13:22.240
<v Speaker 5>problem right now in generally you would say wait a minute,

0:13:22.280 --> 0:13:24.960
<v Speaker 5>in the US, it's less of a problem because most

0:13:24.960 --> 0:13:27.160
<v Speaker 5>people live in a single family house and they have

0:13:27.200 --> 0:13:29.720
<v Speaker 5>a driveway and they have parking garage. But the rest

0:13:29.760 --> 0:13:33.640
<v Speaker 5>of the world, most people live in multi family houses,

0:13:33.760 --> 0:13:37.800
<v Speaker 5>multi story houses, and they don't have parking garage, and

0:13:37.840 --> 0:13:39.720
<v Speaker 5>then looking for parking at the end of the day,

0:13:39.760 --> 0:13:42.640
<v Speaker 5>it's a nightmare. And this is you know, my most

0:13:42.720 --> 0:13:45.520
<v Speaker 5>recent startup that we started that a couple of years

0:13:45.559 --> 0:13:51.000
<v Speaker 5>ago and and it's staling is well and hopefully it

0:13:51.040 --> 0:13:54.120
<v Speaker 5>will grow to address that because parking.

0:13:53.880 --> 0:13:56.160
<v Speaker 6>Is a major problem. Yeah, we could use that in Brooklyn,

0:13:56.800 --> 0:13:58.760
<v Speaker 6>I know. Okay, Well, is something.

0:13:58.480 --> 0:14:00.600
<v Speaker 2>I wonder, you know, when I think about so much.

0:14:00.640 --> 0:14:03.400
<v Speaker 2>This year, we've talked about artificial intelligence and generative AI,

0:14:04.280 --> 0:14:06.679
<v Speaker 2>and some are concerned that it's going to take jobs

0:14:06.679 --> 0:14:09.200
<v Speaker 2>away from people. I see it more as complementary. But

0:14:09.760 --> 0:14:12.920
<v Speaker 2>having said that, I do think about job creation in

0:14:12.960 --> 0:14:17.520
<v Speaker 2>the future because economies, whether it's the Gaza strip, if

0:14:17.520 --> 0:14:19.960
<v Speaker 2>people have a way to make a living and build

0:14:20.000 --> 0:14:23.960
<v Speaker 2>a much more productive life, or whether it's in Israel

0:14:24.080 --> 0:14:28.080
<v Speaker 2>or whether it's in other developing markets, if you can

0:14:28.160 --> 0:14:32.120
<v Speaker 2>create a better life for yourself, it's just a better,

0:14:32.200 --> 0:14:35.200
<v Speaker 2>more peaceful place, right even create an economy. So are

0:14:35.240 --> 0:14:38.040
<v Speaker 2>there I don't know. Are we moving increasingly towards a

0:14:38.080 --> 0:14:42.640
<v Speaker 2>world though, where technology is replacing jobs at a faster

0:14:42.800 --> 0:14:46.840
<v Speaker 2>pace than we can make them Unless you're coder, you know.

0:14:46.920 --> 0:14:49.560
<v Speaker 6>I think that I hear that for the last fifty years.

0:14:49.640 --> 0:14:50.000
<v Speaker 1>Right, So.

0:14:51.600 --> 0:14:55.680
<v Speaker 5>Even if you think of the revolution of agriculture, that

0:14:55.720 --> 0:14:58.880
<v Speaker 5>we started to have tractors and combine the defferent machinery,

0:14:59.120 --> 0:15:01.200
<v Speaker 5>and everyone say it, oh, this is going to take

0:15:01.200 --> 0:15:04.440
<v Speaker 5>away the work of the farmers, and guess what, it didn't.

0:15:04.840 --> 0:15:08.160
<v Speaker 5>So every time that there is an innovation, we tell ourselves, oh,

0:15:08.240 --> 0:15:10.560
<v Speaker 5>this is going to take away all the jobs, and

0:15:10.560 --> 0:15:14.040
<v Speaker 5>then you look at the unemployment rate and it doesn't change,

0:15:14.160 --> 0:15:17.320
<v Speaker 5>or maybe it's becoming better, because what happened is that

0:15:17.320 --> 0:15:21.560
<v Speaker 5>that technology by and large increased productivity. And when it

0:15:21.720 --> 0:15:24.520
<v Speaker 5>increased productivity, then we can create more. And when we

0:15:24.640 --> 0:15:28.240
<v Speaker 5>create more, then more people actually have a better life.

0:15:29.120 --> 0:15:31.480
<v Speaker 2>So not worried about AI in the end of.

0:15:31.520 --> 0:15:33.320
<v Speaker 6>Us all, not at all.

0:15:33.440 --> 0:15:35.920
<v Speaker 5>What I think that we might find out that there

0:15:35.920 --> 0:15:39.360
<v Speaker 5>are some areas that we will need to establish regulation.

0:15:39.840 --> 0:15:44.840
<v Speaker 5>So if I'm speaking with a person, then that's one thing.

0:15:44.920 --> 0:15:47.040
<v Speaker 5>But if I don't know that I'm speaking to a

0:15:47.080 --> 0:15:49.440
<v Speaker 5>machine might be a different thing. So maybe the machine

0:15:49.480 --> 0:15:52.040
<v Speaker 5>will need to identify itself and tells me I'm a

0:15:52.040 --> 0:15:56.400
<v Speaker 5>machine and clear about it. And this is something that

0:15:56.480 --> 0:15:58.520
<v Speaker 5>I think that eventually we will need to have.

0:15:58.960 --> 0:16:02.600
<v Speaker 4>Do you think that AI is close, as Elon Musk

0:16:02.640 --> 0:16:07.640
<v Speaker 4>believes two becoming smarter than humans?

0:16:09.200 --> 0:16:10.080
<v Speaker 2>Wow, that's a big thing.

0:16:10.400 --> 0:16:12.360
<v Speaker 5>No, No, I think that we hear that for the

0:16:12.400 --> 0:16:14.760
<v Speaker 5>last fifty years or computers are going to be smarter

0:16:14.880 --> 0:16:16.800
<v Speaker 5>than people. Oh, we don't need people, We don't need

0:16:16.800 --> 0:16:20.160
<v Speaker 5>the human brain. The human brain something that video fifty

0:16:20.200 --> 0:16:23.800
<v Speaker 5>years ago, right, But then you know, end of the day,

0:16:23.840 --> 0:16:28.680
<v Speaker 5>I think that the creativity and the adaptability is something

0:16:28.840 --> 0:16:31.600
<v Speaker 5>that only humans would have and at the end of

0:16:31.640 --> 0:16:35.480
<v Speaker 5>the day, that part is not going to be taking away. Now,

0:16:35.480 --> 0:16:38.960
<v Speaker 5>whether or not you can scan way more information in

0:16:38.960 --> 0:16:41.640
<v Speaker 5>a fraction of the sick and absolutely yes, Whether or

0:16:41.680 --> 0:16:44.680
<v Speaker 5>not you can process some of the things way faster, yes,

0:16:45.400 --> 0:16:48.720
<v Speaker 5>but not the same order of magnitude what the human

0:16:48.760 --> 0:16:49.360
<v Speaker 5>mind can do.

0:16:50.200 --> 0:16:53.600
<v Speaker 2>Thirty seconds left. We've talked about a lot, and obviously

0:16:53.600 --> 0:16:56.280
<v Speaker 2>it's a very stressful world right now. Final thoughts that

0:16:56.320 --> 0:16:59.000
<v Speaker 2>you want to leave our audience as we get ready

0:16:59.040 --> 0:16:59.680
<v Speaker 2>for a new year.

0:17:01.320 --> 0:17:05.199
<v Speaker 5>So I think that in just about thirty seconds.

0:17:05.280 --> 0:17:05.680
<v Speaker 6>Sorry.

0:17:06.000 --> 0:17:09.399
<v Speaker 5>Value creation, right, value creation when you create value and

0:17:09.400 --> 0:17:11.800
<v Speaker 5>evaluate the way you create for otters, not for yourself.

0:17:12.200 --> 0:17:14.359
<v Speaker 5>If we think about value creation, then we end up

0:17:14.400 --> 0:17:16.080
<v Speaker 5>with a purpose to a life. And when we end

0:17:16.160 --> 0:17:17.720
<v Speaker 5>up with a purpose to a life, we're going to

0:17:17.760 --> 0:17:21.679
<v Speaker 5>be happier and leave wrong here and the war is

0:17:21.720 --> 0:17:22.760
<v Speaker 5>going to be a better place.

0:17:23.800 --> 0:17:26.800
<v Speaker 2>Thank you so much, thank happy new year. To the

0:17:26.840 --> 0:17:30.400
<v Speaker 2>new year is a calmer one, more peaceful one.

0:17:30.160 --> 0:17:31.720
<v Speaker 6>And better one way it will be.

0:17:31.680 --> 0:17:35.240
<v Speaker 2>Okay or OLIVI, thank you so much. Always appreciate it.

0:17:35.240 --> 0:17:37.639
<v Speaker 2>Con founder of Ways and so much more. As we

0:17:37.680 --> 0:17:39.400
<v Speaker 2>talk about we've talked about his book fall in Love

0:17:39.400 --> 0:17:41.639
<v Speaker 2>with the Problem, not the Solution of handbook for entrepreneurs.

0:17:41.680 --> 0:17:43.280
<v Speaker 2>He has it on his T shirt. For those who

0:17:43.280 --> 0:17:44.160
<v Speaker 2>are watching.

0:17:45.160 --> 0:17:48.719
<v Speaker 1>You're listening to the Bloomberg Business Week podcast. Catch us

0:17:48.760 --> 0:17:52.119
<v Speaker 1>live weekday afternoons from three to six Eastern Listen on

0:17:52.160 --> 0:17:56.200
<v Speaker 1>Bloomberg dot com, the iHeartRadio app and the Bloomberg Business app,

0:17:56.480 --> 0:17:58.760
<v Speaker 1>or watch us live on YouTube.

0:18:00.000 --> 0:18:01.040
<v Speaker 2>I mean to the moon.

0:18:02.800 --> 0:18:05.960
<v Speaker 1>Let me play up there with those stars.

0:18:09.160 --> 0:18:12.240
<v Speaker 2>Blue eyes, you know what we're talking about. Space in

0:18:12.280 --> 0:18:12.600
<v Speaker 2>the Moon.

0:18:13.040 --> 0:18:16.359
<v Speaker 4>I do because it's the next frontier.

0:18:16.560 --> 0:18:18.000
<v Speaker 2>For drug manufacturing.

0:18:18.080 --> 0:18:22.520
<v Speaker 4>Yeah, it's really interesting. This story is in the forthcoming

0:18:22.560 --> 0:18:24.800
<v Speaker 4>issue of Bloomberg BusinessWeek magazine. I want to read a

0:18:24.800 --> 0:18:27.600
<v Speaker 4>little bit from it because it's so good. Red Night

0:18:27.640 --> 0:18:30.680
<v Speaker 4>is pigmentosa is a genetic cause of blindness. Some people

0:18:30.680 --> 0:18:33.359
<v Speaker 4>know it as RP. There's no cure or treatment for

0:18:33.440 --> 0:18:36.560
<v Speaker 4>it right now, but there's a startup that's working on it,

0:18:37.119 --> 0:18:39.119
<v Speaker 4>and it has big plans to develop the world's first

0:18:39.200 --> 0:18:44.280
<v Speaker 4>protein based artificial retina, which could help patients who have RP.

0:18:44.720 --> 0:18:48.520
<v Speaker 4>Here's the thing. Manufacturing the retina involves depositing two hundred

0:18:48.680 --> 0:18:51.439
<v Speaker 4>paper thin layers of a light sensitive protein in a

0:18:51.480 --> 0:18:56.000
<v Speaker 4>polymer mesh. Sounds pretty difficult, right, Yeah, Well, it turns

0:18:56.000 --> 0:18:58.200
<v Speaker 4>out the protein layers must be perfectly even for the

0:18:58.240 --> 0:19:01.480
<v Speaker 4>retina to work properly, and that's really difficult to do

0:19:02.040 --> 0:19:02.960
<v Speaker 4>here on planet Earth.

0:19:03.359 --> 0:19:06.399
<v Speaker 2>Right, So the company has turned to the International Space

0:19:06.440 --> 0:19:09.639
<v Speaker 2>Station in the hopes that micro gravity there could help.

0:19:10.160 --> 0:19:14.359
<v Speaker 2>Incredible story. Robert Langreth is healthcare reporter for Bloomberg News,

0:19:14.680 --> 0:19:16.760
<v Speaker 2>and in the forthcoming issue of Bloomberg Business Week, he

0:19:16.800 --> 0:19:19.359
<v Speaker 2>writes about drug companies that are exploring making the most

0:19:19.440 --> 0:19:22.359
<v Speaker 2>lucrative drugs in space. You can read his story now

0:19:22.400 --> 0:19:24.880
<v Speaker 2>on the Bloomberg and at bloomberg dot com Slash business Week.

0:19:24.880 --> 0:19:27.400
<v Speaker 2>Also here with us the editor of Bloomberg BusinessWeek, Jill

0:19:27.400 --> 0:19:30.200
<v Speaker 2>Weber here in our Bloomberg Interactive Broker studio. Tim and

0:19:30.240 --> 0:19:31.720
<v Speaker 2>I read this and we're like, Bob gets to do

0:19:31.840 --> 0:19:33.000
<v Speaker 2>the coolest stories.

0:19:33.760 --> 0:19:34.760
<v Speaker 6>It's always one of those studies.

0:19:34.800 --> 0:19:35.720
<v Speaker 5>We're like, oh my god.

0:19:35.760 --> 0:19:37.119
<v Speaker 4>Although Joel, I don't think he got to go on

0:19:37.160 --> 0:19:38.280
<v Speaker 4>the ISS to do this.

0:19:38.359 --> 0:19:42.480
<v Speaker 3>I mean, you know, it's kind of in a precarious situation,

0:19:42.680 --> 0:19:47.080
<v Speaker 3>this thing with the US and Russia. Anyway, the just

0:19:47.119 --> 0:19:51.000
<v Speaker 3>go to I could send him there bomb you heard

0:19:51.040 --> 0:19:53.360
<v Speaker 3>it from these guys, you have permission so to ask

0:19:53.400 --> 0:19:57.880
<v Speaker 3>at least. So we're started to do a little space package.

0:19:58.280 --> 0:20:00.439
<v Speaker 3>There's a lot happening up there, it turns out, and

0:20:00.480 --> 0:20:03.320
<v Speaker 3>there are some expected things like what SpaceX is up

0:20:03.320 --> 0:20:05.440
<v Speaker 3>to you and the race to catch them, but there's

0:20:05.480 --> 0:20:09.440
<v Speaker 3>also I thought some more interesting things of like applications

0:20:09.480 --> 0:20:12.160
<v Speaker 3>that you've probably never heard of. And it turns out

0:20:12.200 --> 0:20:15.600
<v Speaker 3>that you know, you mentioned micro gravity. There there are

0:20:15.960 --> 0:20:20.000
<v Speaker 3>some novel use cases for what can be accomplished in space.

0:20:20.040 --> 0:20:22.600
<v Speaker 3>So so Bob walk us through it. What is uh,

0:20:22.680 --> 0:20:24.760
<v Speaker 3>what can we do in space that we can't do

0:20:24.840 --> 0:20:26.119
<v Speaker 3>as well here on Earth.

0:20:27.400 --> 0:20:29.200
<v Speaker 7>Yeah, So it turns out, you know, a lot of

0:20:29.240 --> 0:20:32.560
<v Speaker 7>the drugs that drug makers are making these days are

0:20:32.640 --> 0:20:35.760
<v Speaker 7>proteins or things like monocle and antibiodies or cancer drugs,

0:20:35.760 --> 0:20:38.720
<v Speaker 7>and these are that are that are infused. And these

0:20:38.760 --> 0:20:42.399
<v Speaker 7>are you know, complicated, finicky molecules and notoriously difficult to

0:20:42.440 --> 0:20:45.359
<v Speaker 7>produce on Earth in their crystal form. So it turns

0:20:45.359 --> 0:20:47.560
<v Speaker 7>out that without gravity, or without much gravity, you know,

0:20:47.920 --> 0:20:51.240
<v Speaker 7>it becomes much it's much easier to form like a large,

0:20:53.000 --> 0:20:55.879
<v Speaker 7>large and very uniform crystals. And that is it turns out,

0:20:55.920 --> 0:21:00.800
<v Speaker 7>can enhance formulations and even potentially some existing drugs. So

0:21:01.040 --> 0:21:04.160
<v Speaker 7>drug maker merk it's working. It's worked on a new

0:21:04.200 --> 0:21:08.000
<v Speaker 7>formulation of it's just blockbuster cancer drug k Truda. Now

0:21:08.000 --> 0:21:09.960
<v Speaker 7>that's the cancer drug that Jimmy Carter got. It's for

0:21:10.000 --> 0:21:12.840
<v Speaker 7>the melanoman all sorts of other ones, but right now

0:21:13.600 --> 0:21:15.280
<v Speaker 7>it must be infused, like you have to go to

0:21:15.280 --> 0:21:17.680
<v Speaker 7>the doctor's office and infused there over a couple hours.

0:21:18.240 --> 0:21:18.359
<v Speaker 5>Uh.

0:21:18.480 --> 0:21:20.399
<v Speaker 7>And the dry it would really like to put that

0:21:20.440 --> 0:21:23.280
<v Speaker 7>in injectable forms, you could do just a self administered injection,

0:21:23.400 --> 0:21:25.120
<v Speaker 7>potentially even at home. But to do that, it needs

0:21:25.119 --> 0:21:27.239
<v Speaker 7>to be able to concentrate that con true to much

0:21:27.240 --> 0:21:29.399
<v Speaker 7>more to be concentrated now, and if you did it

0:21:29.400 --> 0:21:32.119
<v Speaker 7>with the current formulation, to be get like molasses. So

0:21:32.160 --> 0:21:34.119
<v Speaker 7>it turns out they did some experiments in space and

0:21:34.200 --> 0:21:36.199
<v Speaker 7>the International Space Station and they came up with a

0:21:36.240 --> 0:21:39.440
<v Speaker 7>way to concentrate it much more and keep it fast flowing,

0:21:39.880 --> 0:21:42.040
<v Speaker 7>and that was experiment using microgravity.

0:21:44.880 --> 0:21:46.440
<v Speaker 2>It's a little bit of freezing. We're we're trying to

0:21:46.560 --> 0:21:47.880
<v Speaker 2>freeze them and then bring Bob back.

0:21:49.840 --> 0:21:51.760
<v Speaker 4>It's like you're joining us from the International Space Station.

0:21:52.240 --> 0:21:56.399
<v Speaker 4>You actual you know, please pause for we wanted to

0:21:56.480 --> 0:21:57.600
<v Speaker 4>be realistic.

0:21:57.640 --> 0:21:57.840
<v Speaker 1>Job.

0:21:57.880 --> 0:22:00.600
<v Speaker 4>I'm sorry, continue about taking about keep I'm sorry.

0:22:00.640 --> 0:22:02.960
<v Speaker 7>I got a thing saying my internet connection was unstable.

0:22:02.960 --> 0:22:04.879
<v Speaker 7>I haven't gotten that all day until I.

0:22:04.640 --> 0:22:06.160
<v Speaker 3>Remember that's how I remember the pandemic.

0:22:06.400 --> 0:22:10.600
<v Speaker 7>Yeah, yeahs, no problem, that's the first time.

0:22:11.560 --> 0:22:11.760
<v Speaker 8>Yeah.

0:22:11.800 --> 0:22:13.920
<v Speaker 7>So Mark is working on a new formulation of cap

0:22:14.000 --> 0:22:18.320
<v Speaker 7>Truda's it's big selling drug that was kind of first

0:22:18.359 --> 0:22:21.399
<v Speaker 7>the concept for was first device in space, and the

0:22:21.440 --> 0:22:23.520
<v Speaker 7>fact that they might go into clinical trials is something

0:22:23.560 --> 0:22:26.120
<v Speaker 7>that was the first you know devised in space that's

0:22:26.160 --> 0:22:28.399
<v Speaker 7>excited a lot of gotten a lot of interest in

0:22:28.440 --> 0:22:30.480
<v Speaker 7>you know, space based drug development.

0:22:31.160 --> 0:22:31.440
<v Speaker 1>Uh.

0:22:31.480 --> 0:22:33.560
<v Speaker 7>And other companies like Eli Lilly is up there with

0:22:33.600 --> 0:22:36.919
<v Speaker 7>some experiments now and you even now have startups that

0:22:37.080 --> 0:22:40.600
<v Speaker 7>once the International Space Station is decommissioned, you know, sometime

0:22:40.680 --> 0:22:43.119
<v Speaker 7>after twenty thirty that are working on developing you know,

0:22:43.240 --> 0:22:47.480
<v Speaker 7>automated kind of drug formulation laboratories in space. It'd send

0:22:47.560 --> 0:22:49.919
<v Speaker 7>some experiment up and then it come back down and

0:22:50.160 --> 0:22:51.359
<v Speaker 7>drug companies could work on it.

0:22:51.520 --> 0:22:55.760
<v Speaker 3>Okay, so when does this happen? Why don't we have

0:22:55.840 --> 0:22:56.720
<v Speaker 3>this already? Bob?

0:22:58.480 --> 0:23:00.879
<v Speaker 7>Well, you know, these are all kind of like, you know,

0:23:01.200 --> 0:23:02.760
<v Speaker 7>I'd like to say, these are all kind of like

0:23:02.840 --> 0:23:05.679
<v Speaker 7>early experiments. So say they're drug companies and setting up

0:23:05.720 --> 0:23:07.760
<v Speaker 7>experiments by the way out into space for really for

0:23:07.840 --> 0:23:11.040
<v Speaker 7>decades and there their first experiments were kind of like

0:23:11.200 --> 0:23:15.600
<v Speaker 7>early stage aimed at like early stage drug crystallization, where

0:23:15.640 --> 0:23:19.120
<v Speaker 7>to crystallize GOT disease, promote promoting proteins so they could

0:23:19.119 --> 0:23:22.240
<v Speaker 7>design better drugs. And in fact, a unit of a

0:23:22.359 --> 0:23:25.680
<v Speaker 7>Suka Holdings that's a Japanese company, they have a drug

0:23:25.960 --> 0:23:29.680
<v Speaker 7>in final stage trials in Japan for muscular dystrophe. There

0:23:29.760 --> 0:23:32.760
<v Speaker 7>was was base and some very early work you know,

0:23:32.920 --> 0:23:35.359
<v Speaker 7>done early in the early days of International space study

0:23:35.640 --> 0:23:40.040
<v Speaker 7>space station crystallizing a muscular dystrophy associated protein. But what's

0:23:40.080 --> 0:23:43.240
<v Speaker 7>happening now is there actually Americans and others are showing

0:23:43.280 --> 0:23:46.840
<v Speaker 7>you could actually devise you know, better formulations on existing

0:23:46.840 --> 0:23:49.879
<v Speaker 7>blockbuster drugs. And that's really driven the attention to like

0:23:50.160 --> 0:23:52.960
<v Speaker 7>maybe you know space is like, you know, could really

0:23:53.040 --> 0:23:54.679
<v Speaker 7>like help us get some new patents and make a

0:23:54.680 --> 0:23:56.359
<v Speaker 7>lot of money. So that's really driven interest.

0:23:56.720 --> 0:23:59.760
<v Speaker 3>So whose job is it to figure out how to

0:23:59.800 --> 0:24:03.560
<v Speaker 3>do this in space? Like, you know, Tim, Tim, if

0:24:03.560 --> 0:24:06.440
<v Speaker 3>you're gonna make you know, car breaks in space, I'm

0:24:06.480 --> 0:24:08.520
<v Speaker 3>sure you can figure that out. But Bob, what about it?

0:24:08.680 --> 0:24:10.280
<v Speaker 4>You don't want to see how far I made it

0:24:10.480 --> 0:24:12.920
<v Speaker 4>the math but in college?

0:24:13.000 --> 0:24:16.800
<v Speaker 3>But uh, but within pharmat like, whose job is it

0:24:16.840 --> 0:24:18.400
<v Speaker 3>to figure out space manufacturing?

0:24:19.760 --> 0:24:21.960
<v Speaker 7>Yeah, so at the big you know, drug makers, there's

0:24:22.000 --> 0:24:25.159
<v Speaker 7>relatively you know, small numbers of people like working on it,

0:24:25.160 --> 0:24:27.119
<v Speaker 7>so it's still a niche field. I'd say, you know,

0:24:27.119 --> 0:24:29.040
<v Speaker 7>if you go to a big drugmaker, I would imagine

0:24:29.040 --> 0:24:31.160
<v Speaker 7>there's probably a lot more people working on AI than space,

0:24:31.280 --> 0:24:33.760
<v Speaker 7>but you know, you know, space is like you know,

0:24:34.359 --> 0:24:36.960
<v Speaker 7>garnering interest. Some of the people I talked to, their

0:24:37.000 --> 0:24:40.560
<v Speaker 7>titles are like, you know, director of formulations, development titles

0:24:40.560 --> 0:24:44.359
<v Speaker 7>like that. But these experiments are are hard. You know,

0:24:44.440 --> 0:24:46.679
<v Speaker 7>you you sent something up to the space station and

0:24:47.480 --> 0:24:49.600
<v Speaker 7>you know you get it back down a few months later,

0:24:49.720 --> 0:24:52.000
<v Speaker 7>and if you like screwed up in the design and experiment,

0:24:52.040 --> 0:24:54.119
<v Speaker 7>you know your next shot or the next experiment maybe

0:24:54.160 --> 0:24:56.600
<v Speaker 7>you know six months later. So you gotta got you

0:24:56.640 --> 0:24:59.680
<v Speaker 7>gotta do it. Be very careful with experimental design. You can't,

0:24:59.760 --> 0:25:01.880
<v Speaker 7>like it's hard to call an astro and say, hey,

0:25:01.880 --> 0:25:04.120
<v Speaker 7>I want to change everything midstream once is up there.

0:25:04.160 --> 0:25:07.240
<v Speaker 7>So there's even a whole set of like companies that

0:25:07.400 --> 0:25:10.359
<v Speaker 7>help drug makers like have like self enclosed experiments that

0:25:10.440 --> 0:25:11.640
<v Speaker 7>can send up that are like.

0:25:11.640 --> 0:25:12.359
<v Speaker 1>All ready to go.

0:25:12.480 --> 0:25:14.639
<v Speaker 7>The astront presses a couple buttons to turn it on

0:25:14.680 --> 0:25:16.480
<v Speaker 7>and then presses a couple buttons to turn it off.

0:25:16.800 --> 0:25:18.800
<v Speaker 7>You know, you can't. It's hard to adjust the audition

0:25:19.240 --> 0:25:20.600
<v Speaker 7>midstream once you're up in space.

0:25:20.960 --> 0:25:25.639
<v Speaker 4>The button pressing job it doesn't sound bad. So Bob,

0:25:25.920 --> 0:25:27.600
<v Speaker 4>I want to get to this idea of scaling and

0:25:27.600 --> 0:25:29.679
<v Speaker 4>make sure I understand what's actually happening in space. I

0:25:29.720 --> 0:25:31.520
<v Speaker 4>want to go back to the company that you used

0:25:31.520 --> 0:25:33.480
<v Speaker 4>in the lead here, LAMB Division, who's working on the

0:25:33.520 --> 0:25:38.639
<v Speaker 4>world's first protein based artificial retina for patients with retinitis pigmentosa. So,

0:25:39.520 --> 0:25:43.639
<v Speaker 4>if it's so hard to actually create these two hundred

0:25:43.640 --> 0:25:48.960
<v Speaker 4>paper thin layers of light sensitive protein in on Earth,

0:25:49.520 --> 0:25:52.439
<v Speaker 4>does that mean that they won't be able to scale

0:25:52.480 --> 0:25:55.640
<v Speaker 4>it in an environment that's not zero gravity.

0:25:56.880 --> 0:25:57.120
<v Speaker 1>Yeah.

0:25:57.160 --> 0:25:59.320
<v Speaker 7>So they're one of the few companies that's right now

0:25:59.480 --> 0:26:03.040
<v Speaker 7>is talking about actually, as I understand it, manufacturing finished product,

0:26:03.080 --> 0:26:05.720
<v Speaker 7>you know, in space. And if you think about their product,

0:26:05.760 --> 0:26:08.560
<v Speaker 7>it's like literally it's a size of a whole punch,

0:26:09.240 --> 0:26:11.000
<v Speaker 7>like a paper whole punch. That's like, you know, so

0:26:11.040 --> 0:26:12.520
<v Speaker 7>you get I guess you get one or two of

0:26:12.560 --> 0:26:15.439
<v Speaker 7>these if you're a patient. So they don't need that

0:26:15.560 --> 0:26:18.480
<v Speaker 7>much finished product. You know, it's a relatively small market.

0:26:19.000 --> 0:26:21.000
<v Speaker 7>I mean, this is not like an infused drug where

0:26:21.040 --> 0:26:23.040
<v Speaker 7>you're going to be giving you know, two hundred millilters

0:26:23.080 --> 0:26:25.000
<v Speaker 7>every two weeks for the rest of your life. That's

0:26:25.440 --> 0:26:27.679
<v Speaker 7>more like merks K true to the they make it,

0:26:27.840 --> 0:26:30.199
<v Speaker 7>Mark and K true to their cancer drug. They make

0:26:30.200 --> 0:26:32.719
<v Speaker 7>it like by the ton on Earth and their experiments

0:26:32.720 --> 0:26:34.719
<v Speaker 7>in space. So far, I've made like one dose at

0:26:34.760 --> 0:26:37.040
<v Speaker 7>a time, so you can see that it's not right

0:26:37.080 --> 0:26:39.720
<v Speaker 7>now practical wouldn't be even if there are even though

0:26:39.720 --> 0:26:42.320
<v Speaker 7>there are technical advantages, it would not be practical for

0:26:42.359 --> 0:26:44.320
<v Speaker 7>them to make the finished product in space. But for

0:26:44.400 --> 0:26:47.720
<v Speaker 7>something like this artificial retina, where the total quantities needed

0:26:47.760 --> 0:26:50.440
<v Speaker 7>are very very small, and I imagine if they ever

0:26:50.480 --> 0:26:52.000
<v Speaker 7>get this to market, it's going to be sold for

0:26:52.040 --> 0:26:54.920
<v Speaker 7>a very high price. You know, you can imagine that's

0:26:54.960 --> 0:26:58.320
<v Speaker 7>an actual like possibility to actually make that in space.

0:26:58.400 --> 0:27:01.560
<v Speaker 3>Would you take the one that's been made in space,

0:27:01.800 --> 0:27:08.159
<v Speaker 3>knowing that there's massive quantities on Earth, it's practically the

0:27:08.160 --> 0:27:10.080
<v Speaker 3>same thing. It's just been made in space. Like, why

0:27:10.080 --> 0:27:11.479
<v Speaker 3>wouldn't Why wouldn't I do it?

0:27:11.520 --> 0:27:12.560
<v Speaker 6>Why not?

0:27:13.080 --> 0:27:15.359
<v Speaker 3>I don't know.

0:27:16.880 --> 0:27:20.320
<v Speaker 7>That the regulatory question no one's even gotten to, Like,

0:27:20.440 --> 0:27:22.800
<v Speaker 7>you know, if something actually were made in space, or

0:27:22.840 --> 0:27:25.359
<v Speaker 7>even if like there's another idea they're talking about. It's

0:27:25.359 --> 0:27:27.640
<v Speaker 7>making like a seed crystal in space, use the better

0:27:27.680 --> 0:27:30.000
<v Speaker 7>conditions of space to make like little seed crystals that

0:27:30.000 --> 0:27:31.760
<v Speaker 7>they could then be used sort of like a sour

0:27:31.800 --> 0:27:34.159
<v Speaker 7>to start being brought down to Earth and able to

0:27:34.160 --> 0:27:38.080
<v Speaker 7>grow bigger quantities on Earth. But even there, like the FDA,

0:27:38.160 --> 0:27:40.440
<v Speaker 7>how would the FDA regulate that, there's a whole I

0:27:40.440 --> 0:27:42.399
<v Speaker 7>guess said of unknown like questions there.

0:27:42.560 --> 0:27:44.760
<v Speaker 2>Yeah, FDA is not having any problems with oversight. We

0:27:44.800 --> 0:27:48.480
<v Speaker 2>did that story actually earlier today. Having said that, how

0:27:48.520 --> 0:27:52.200
<v Speaker 2>easy is did you duplicate the process of space drug

0:27:52.359 --> 0:27:56.199
<v Speaker 2>or manufacturing drugs in space on Earth? Can we create that?

0:27:56.320 --> 0:27:56.959
<v Speaker 2>Recreate that?

0:27:59.000 --> 0:27:59.280
<v Speaker 1>Yeah?

0:27:59.320 --> 0:28:00.720
<v Speaker 7>So the way to think of it with some of

0:28:00.760 --> 0:28:03.399
<v Speaker 7>these drug formulations are trying to make better like easier

0:28:03.400 --> 0:28:06.400
<v Speaker 7>to use injectable drug formulations, And the way to think

0:28:06.440 --> 0:28:09.280
<v Speaker 7>about that is that there's just like you know, there's

0:28:09.320 --> 0:28:11.600
<v Speaker 7>a million conditions you can put in to get something

0:28:11.600 --> 0:28:16.840
<v Speaker 7>to crystallize. The temperature, the pressure, you know, the concentrations, many,

0:28:16.880 --> 0:28:19.000
<v Speaker 7>many conditions you can try almost an infinite number, and

0:28:19.119 --> 0:28:21.760
<v Speaker 7>just things form a little without the microgravity because crystals

0:28:21.760 --> 0:28:25.480
<v Speaker 7>are these kind of slow forming, finicky things, and without

0:28:25.840 --> 0:28:28.120
<v Speaker 7>the convection is one of the things that goes away

0:28:28.160 --> 0:28:31.640
<v Speaker 7>the fluid convections, so and that's reduced and that gets better,

0:28:31.800 --> 0:28:35.119
<v Speaker 7>just gets better quality crystals in many cases. And so

0:28:35.160 --> 0:28:36.840
<v Speaker 7>the way to think about it is they get an

0:28:36.840 --> 0:28:39.760
<v Speaker 7>idea in space like in these better conditions, and then

0:28:39.840 --> 0:28:43.680
<v Speaker 7>once they know what they're looking for, they then find

0:28:43.760 --> 0:28:46.160
<v Speaker 7>you find a way to duplicate that back at the

0:28:46.160 --> 0:28:48.960
<v Speaker 7>factory here on Earth. And that's what Merk did with

0:28:49.000 --> 0:28:51.400
<v Speaker 7>this new formulation of k truda that may go into

0:28:51.400 --> 0:28:52.160
<v Speaker 7>clinical trials.

0:28:52.200 --> 0:28:54.400
<v Speaker 3>Okay, So so Merk seems to be all over this.

0:28:54.760 --> 0:28:58.680
<v Speaker 3>What about other drug manufacturers are you know, is there

0:28:58.720 --> 0:29:02.440
<v Speaker 3>really a race like as often is the case in

0:29:02.520 --> 0:29:06.120
<v Speaker 3>space space for drug or or is everybody else.

0:29:06.800 --> 0:29:10.760
<v Speaker 7>Under space race? Mark has a competitor in cancer drugs,

0:29:10.760 --> 0:29:13.920
<v Speaker 7>and that's Bristol Myers Squid and they make a rival

0:29:13.960 --> 0:29:17.080
<v Speaker 7>to k truda called Updivo, and they indeed are putting

0:29:17.120 --> 0:29:20.680
<v Speaker 7>experiments up into space like you're looking at protein crystallation,

0:29:21.120 --> 0:29:23.960
<v Speaker 7>you know, and uh, you know, they they do say

0:29:23.960 --> 0:29:26.080
<v Speaker 7>it includes cancer, but they won't to say which drugs

0:29:26.120 --> 0:29:29.080
<v Speaker 7>and are involved. But all I can say is they

0:29:29.120 --> 0:29:32.200
<v Speaker 7>do make a direct rival to k truda. So, you know,

0:29:32.360 --> 0:29:35.440
<v Speaker 7>drug companies, you know, historically, you know, once one company

0:29:35.480 --> 0:29:37.400
<v Speaker 7>does something, you know the others want to try it out.

0:29:37.640 --> 0:29:41.040
<v Speaker 2>Wait, not like a dry diet drug or anything.

0:29:42.200 --> 0:29:44.240
<v Speaker 7>Well, so far I've not heard of any diet drugs

0:29:44.280 --> 0:29:47.520
<v Speaker 7>you know that maide in space. But uh, you know,

0:29:47.640 --> 0:29:48.480
<v Speaker 7>I'll keep reporting.

0:29:48.920 --> 0:29:52.880
<v Speaker 3>We should make journalism in space just just.

0:29:52.480 --> 0:29:54.200
<v Speaker 4>Just volunteering together.

0:29:54.240 --> 0:29:56.560
<v Speaker 3>I mean, you know, Bob, Bob was already going to

0:29:56.600 --> 0:30:00.200
<v Speaker 3>go check it out most cost effectively, Bob.

0:30:00.040 --> 0:30:03.520
<v Speaker 4>See if that corporate card will cover that SpaceX trip.

0:30:03.560 --> 0:30:06.240
<v Speaker 2>Okay, Hey, listen, I hate to be a bummer on

0:30:06.320 --> 0:30:09.320
<v Speaker 2>all of this, but isn't the International Space Station at

0:30:09.400 --> 0:30:12.440
<v Speaker 2>risk of being decommissioned after twenty thirty? So, like does

0:30:12.480 --> 0:30:14.000
<v Speaker 2>that put kind of a damp run all on this?

0:30:14.680 --> 0:30:17.920
<v Speaker 7>Well, there's companies like, you know, there's like private startups

0:30:17.920 --> 0:30:19.840
<v Speaker 7>and companies like are working on like what's after the

0:30:19.880 --> 0:30:22.800
<v Speaker 7>space station. There's one small one, you know, startup that

0:30:22.840 --> 0:30:25.200
<v Speaker 7>actually has like a little satellite that's like a little

0:30:25.280 --> 0:30:27.480
<v Speaker 7>drug production lab. They hope it's gonna be a little

0:30:27.480 --> 0:30:31.160
<v Speaker 7>automated drug formulation production lab up there. Now for their

0:30:31.200 --> 0:30:35.200
<v Speaker 7>first mission, they've had some problems getting the reentry capsule

0:30:35.240 --> 0:30:41.360
<v Speaker 7>back down because they need FAA Federal Aviation Administration permission.

0:30:41.360 --> 0:30:42.880
<v Speaker 7>They haven't been able to get it yet. So it

0:30:42.960 --> 0:30:48.320
<v Speaker 7>illustrates some of like, you know, the potential snags involved

0:30:48.320 --> 0:30:49.480
<v Speaker 7>in space based production.

0:30:49.800 --> 0:30:53.200
<v Speaker 3>Yeah, okay, well we know where Big Farmer is, which

0:30:53.240 --> 0:30:56.240
<v Speaker 3>is the final frontier. You know, I'm curious to see

0:30:56.240 --> 0:30:59.040
<v Speaker 3>if if this is for real though, I mean, like, sure,

0:30:59.080 --> 0:31:03.400
<v Speaker 3>you can make a couple applications, but scale seems maybe

0:31:03.480 --> 0:31:07.080
<v Speaker 3>not easy to get there. Tim's going to try break

0:31:07.120 --> 0:31:08.240
<v Speaker 3>pads and report back.

0:31:08.360 --> 0:31:11.360
<v Speaker 4>But the payoff is potentially huge here. I mean, if

0:31:11.400 --> 0:31:14.479
<v Speaker 4>you can cure blindness with artificial retinas, Like even though

0:31:14.520 --> 0:31:17.040
<v Speaker 4>Bob says it's a relatively small number of people, I mean,

0:31:17.400 --> 0:31:18.960
<v Speaker 4>people would pay so much for that.

0:31:19.160 --> 0:31:22.960
<v Speaker 3>You you need, you know, some microgravity, what's that? That's

0:31:22.960 --> 0:31:23.880
<v Speaker 3>why it's there for you.

0:31:24.320 --> 0:31:26.040
<v Speaker 7>I think the key word we use in the headline

0:31:26.120 --> 0:31:29.480
<v Speaker 7>is that the drug companies are exploring this, you know, yeah, right,

0:31:29.520 --> 0:31:31.720
<v Speaker 7>not a deal, and you know, I think the way

0:31:31.760 --> 0:31:33.720
<v Speaker 7>to think of it, they're doing experiments up there that

0:31:33.880 --> 0:31:36.280
<v Speaker 7>are going to help help them, you know, devise new

0:31:36.320 --> 0:31:39.200
<v Speaker 7>formulations and new versions of their drugs. But it doesn't

0:31:39.240 --> 0:31:41.720
<v Speaker 7>necessarily I mean those are actually those final drugs are

0:31:41.720 --> 0:31:43.160
<v Speaker 7>actually going to be produced in space.

0:31:43.320 --> 0:31:45.719
<v Speaker 3>I think we call that the to be sure graph

0:31:46.960 --> 0:31:49.680
<v Speaker 3>implement or the third word in the headline.

0:31:49.120 --> 0:31:51.040
<v Speaker 2>Well, I'm just going to say thank you, Bob, because

0:31:51.040 --> 0:31:53.160
<v Speaker 2>I've been just saying drugs in space.

0:31:54.280 --> 0:31:55.360
<v Speaker 3>It sounds really cool.

0:31:56.000 --> 0:31:58.920
<v Speaker 2>It does sound really cool. I'm very interesting in terms

0:31:59.000 --> 0:32:01.640
<v Speaker 2>of maybe we could see down the road. Bub Landgreth,

0:32:01.720 --> 0:32:03.959
<v Speaker 2>thank you so much. Everything you do is just, uh,

0:32:04.160 --> 0:32:06.600
<v Speaker 2>we learned something and it's a fun read and interesting read.

0:32:06.840 --> 0:32:10.120
<v Speaker 2>Healthcare reporter here at Bloomberg News on zoom in San Francisco.

0:32:10.200 --> 0:32:13.120
<v Speaker 2>He is not on the International Space Dage.

0:32:12.960 --> 0:32:15.320
<v Speaker 4>So as far as we know, despite the fact that

0:32:15.320 --> 0:32:18.800
<v Speaker 4>there were some Internet connectivity issues. But yeah, you never know,

0:32:18.920 --> 0:32:21.640
<v Speaker 4>really really interesting stuff. I'll be the guy who presses

0:32:21.640 --> 0:32:23.960
<v Speaker 4>the button stroll that sounds like we can.

0:32:23.760 --> 0:32:24.280
<v Speaker 3>Fight over it.

0:32:24.840 --> 0:32:27.280
<v Speaker 2>Exactly what he has Joe Webber, of course, the editor

0:32:27.280 --> 0:32:29.920
<v Speaker 2>of Bloomberg Business We check this out in the upcoming

0:32:29.960 --> 0:32:31.320
<v Speaker 2>new issue of Bloomberg Business Week.

0:32:31.360 --> 0:32:32.960
<v Speaker 5>It's also online.

0:32:34.120 --> 0:32:36.040
<v Speaker 2>M MAC.

0:32:37.640 --> 0:32:40.320
<v Speaker 5>The journal. Now about you let me drive?

0:32:40.840 --> 0:32:44.920
<v Speaker 1>No, no, no, honey, please, I'll.

0:32:46.720 --> 0:32:46.880
<v Speaker 6>Wait.

0:32:47.160 --> 0:32:47.880
<v Speaker 3>I want to drive.

0:32:50.120 --> 0:32:51.000
<v Speaker 5>It's a question.

0:32:54.840 --> 0:32:58.880
<v Speaker 1>This is the drive to the globe. We'll buy around

0:32:58.960 --> 0:33:01.280
<v Speaker 1>each other down on Bloomberg Radio.

0:33:01.440 --> 0:33:04.560
<v Speaker 2>All right, everybody, just about seventeen minutes left in today's

0:33:04.560 --> 0:33:07.600
<v Speaker 2>trading session. Right here on Bloomberg BusinessWeek, Carol Master, along

0:33:07.600 --> 0:33:09.880
<v Speaker 2>with Tim Stanovick, Hey Tim, among our most read on

0:33:09.880 --> 0:33:12.560
<v Speaker 2>the Bloomberg. It's one about the message coming from Wall

0:33:12.560 --> 0:33:17.440
<v Speaker 2>Street about investor optimism running dangerously high. It points about

0:33:18.080 --> 0:33:21.200
<v Speaker 2>our points to overstretched technicals and the belief that the

0:33:21.280 --> 0:33:24.920
<v Speaker 2>Fed will not cut interest traits as quickly as markets expect,

0:33:25.240 --> 0:33:29.040
<v Speaker 2>are behind a pessimistic turn from equity specialists over JP Morgan, Chase,

0:33:29.080 --> 0:33:31.800
<v Speaker 2>Morgan Stanley. I mean people who just kind of saying,

0:33:32.000 --> 0:33:33.400
<v Speaker 2>flow your role a little bit.

0:33:33.440 --> 0:33:35.480
<v Speaker 4>I mean, it's been a kind of a wild five

0:33:35.560 --> 0:33:38.560
<v Speaker 4>or six weeks, hasn't it. As Golden Sachs the point right, Yeah.

0:33:38.680 --> 0:33:41.200
<v Speaker 4>Managing director Scott Rubner put it in a report there

0:33:41.320 --> 0:33:43.720
<v Speaker 4>a quote no longer any bears left.

0:33:43.800 --> 0:33:45.640
<v Speaker 2>It's pretty amazing. Let's see what our driver to the

0:33:45.640 --> 0:33:47.920
<v Speaker 2>closed guest has to say about that. With us back

0:33:47.960 --> 0:33:50.280
<v Speaker 2>with us as Aaron Kennon, CEO over at Clear Harbor

0:33:50.320 --> 0:33:52.320
<v Speaker 2>Asset Management. He's co founder of the firm. They've got

0:33:52.320 --> 0:33:55.040
<v Speaker 2>about a billion in assets under management. He joins us

0:33:55.040 --> 0:33:57.840
<v Speaker 2>on Zoom from Stanford, Connecticut. Aaron, good to have you

0:33:57.920 --> 0:34:00.400
<v Speaker 2>back with us. Are there any bears left?

0:34:01.280 --> 0:34:04.040
<v Speaker 8>Well, that's a great question. If you look at the

0:34:04.160 --> 0:34:06.800
<v Speaker 8>underbelly of the market, Carroll and Tim, I mean, certainly

0:34:07.120 --> 0:34:09.560
<v Speaker 8>there's a lot of caution. I think that that can

0:34:09.560 --> 0:34:11.320
<v Speaker 8>be seen. You know, look at the four or ninety

0:34:11.320 --> 0:34:14.760
<v Speaker 8>three stocks outside the S and P five hundreds, Magnificent seven.

0:34:15.280 --> 0:34:17.399
<v Speaker 8>They're only up a few percentage points on a year

0:34:17.440 --> 0:34:20.640
<v Speaker 8>to date basis, and those seven stocks are up about

0:34:20.719 --> 0:34:23.160
<v Speaker 8>ninety seven percent. So I think there's a tale of

0:34:23.200 --> 0:34:28.080
<v Speaker 8>two stories going on across the market. Even global indices.

0:34:27.560 --> 0:34:28.240
<v Speaker 3>For that matter.

0:34:28.360 --> 0:34:30.799
<v Speaker 8>You look at the All World Index and it's about

0:34:30.840 --> 0:34:35.480
<v Speaker 8>eighteen percent allocated to the Magnificent seven, and so pe

0:34:35.600 --> 0:34:38.160
<v Speaker 8>multiples on those four hundred ninety three stocks are trading

0:34:38.200 --> 0:34:41.319
<v Speaker 8>at about sixteen times or so, and the Magnificent seven

0:34:41.360 --> 0:34:44.960
<v Speaker 8>are trading trailing at about fifty times. And so maybe

0:34:44.960 --> 0:34:47.360
<v Speaker 8>that's the glass half full point that, you know, the

0:34:47.400 --> 0:34:49.359
<v Speaker 8>rest of the market, even though we haven't seen much

0:34:49.360 --> 0:34:52.799
<v Speaker 8>of a move higher from a performance perspective, this year,

0:34:53.320 --> 0:34:56.080
<v Speaker 8>could have could have some legs in twenty twenty four

0:34:56.280 --> 0:34:59.720
<v Speaker 8>if the economic picture is relatively okay.

0:35:00.040 --> 0:35:01.480
<v Speaker 4>Do you think the economic picture is going to be

0:35:01.520 --> 0:35:02.640
<v Speaker 4>relatively okay next year?

0:35:03.560 --> 0:35:07.279
<v Speaker 8>Well, I think a lot hinges Tim on employment. You know,

0:35:07.280 --> 0:35:11.600
<v Speaker 8>we saw the jolts data today weaker than expective, but

0:35:12.160 --> 0:35:16.880
<v Speaker 8>you know, certainly still relatively strong. Jobless claims have trended

0:35:17.400 --> 0:35:20.920
<v Speaker 8>downward on a trend line basis, but still relatively strong.

0:35:21.080 --> 0:35:24.160
<v Speaker 8>And we'll have a read through on the job's data too,

0:35:25.640 --> 0:35:29.919
<v Speaker 8>and so on the jobless non farm payrolls data too

0:35:30.640 --> 0:35:34.080
<v Speaker 8>later on so in the week. So I think a

0:35:34.080 --> 0:35:37.480
<v Speaker 8>lot will hinge on the employment picture if the GDP

0:35:38.239 --> 0:35:41.880
<v Speaker 8>and economic data set more generally rolls over and we

0:35:42.000 --> 0:35:46.399
<v Speaker 8>go into a more recessionary like period in twenty twenty

0:35:46.400 --> 0:35:50.560
<v Speaker 8>four from multiple quarters. Even if we have a disinflationary

0:35:51.400 --> 0:35:54.200
<v Speaker 8>continuation with the FED cutting rates, I think that's probably

0:35:54.200 --> 0:35:56.240
<v Speaker 8>bad for equities, But I think that there's a scenario

0:35:56.360 --> 0:35:59.440
<v Speaker 8>that could very well play out where growth remains positive,

0:35:59.520 --> 0:36:06.359
<v Speaker 8>maybe trends lower, but positive, and disinflation continues. That could

0:36:06.360 --> 0:36:10.839
<v Speaker 8>be very bullish for both bonds and potentially equities where

0:36:10.880 --> 0:36:13.439
<v Speaker 8>that correlation remains positive in twenty four.

0:36:13.640 --> 0:36:14.320
<v Speaker 3>Is that likely?

0:36:14.640 --> 0:36:17.000
<v Speaker 2>Might it happen? Where would you place your bet in

0:36:17.080 --> 0:36:19.600
<v Speaker 2>terms of the scenario for next year or do you

0:36:19.600 --> 0:36:21.800
<v Speaker 2>feel like it's kind of up for grabs right now?

0:36:22.440 --> 0:36:24.040
<v Speaker 8>I mean, I think it's somewhat up for grabs. But

0:36:24.080 --> 0:36:26.759
<v Speaker 8>I just point of caution is employment is the last

0:36:26.840 --> 0:36:29.680
<v Speaker 8>leg of the stool that tends to break as we

0:36:30.040 --> 0:36:35.040
<v Speaker 8>enter a recessionary period, and that has just started to

0:36:35.080 --> 0:36:38.760
<v Speaker 8>soften on the margin here, while other data sets carol

0:36:38.800 --> 0:36:42.200
<v Speaker 8>like manufacturing and some indications on the consumer, whether it's

0:36:42.200 --> 0:36:46.680
<v Speaker 8>credit card lines, I mean just the student loan repayments

0:36:46.719 --> 0:36:49.319
<v Speaker 8>just restarted at the end of October, and so I

0:36:49.360 --> 0:36:54.719
<v Speaker 8>think there's still some negative headwinds that are going to

0:36:54.920 --> 0:36:57.799
<v Speaker 8>work through the pipeline as we enter twenty twenty four,

0:36:58.160 --> 0:37:00.759
<v Speaker 8>which is also why I think we should expect at

0:37:00.840 --> 0:37:02.480
<v Speaker 8>least a deceleration in GDP.

0:37:02.920 --> 0:37:06.920
<v Speaker 4>What are some other reasons, other reasons for yeah, for

0:37:07.040 --> 0:37:08.200
<v Speaker 4>a deceleration and GDP.

0:37:09.440 --> 0:37:13.680
<v Speaker 8>Well, I mean you look at China, Tim Good Good example,

0:37:14.280 --> 0:37:18.040
<v Speaker 8>this year, as we waded into twenty twenty three, everyone thought, well,

0:37:18.080 --> 0:37:20.719
<v Speaker 8>China's going to reopen, and the back half of twenty

0:37:20.880 --> 0:37:23.080
<v Speaker 8>twenty three is going to be all about China exporting

0:37:23.120 --> 0:37:27.640
<v Speaker 8>inflation and exporting growth in economic activity. I think that's

0:37:27.680 --> 0:37:31.800
<v Speaker 8>a big question mark for the overall global economy. Frankly,

0:37:33.000 --> 0:37:35.839
<v Speaker 8>my sense is just looking at the data set there

0:37:35.920 --> 0:37:39.680
<v Speaker 8>that things are quite weak. You look at personal bankruptcy

0:37:39.760 --> 0:37:42.879
<v Speaker 8>data in China is skyrocketing. You look at the real

0:37:43.000 --> 0:37:45.160
<v Speaker 8>estate picture on the commercial side in China and the

0:37:45.160 --> 0:37:48.920
<v Speaker 8>delinquencies and defaults happening there, it's a rather significant problem.

0:37:48.920 --> 0:37:53.520
<v Speaker 8>They tried to transition their economy from an export driven

0:37:53.560 --> 0:37:58.920
<v Speaker 8>economy to a consumer growth, domestic growth driven economy, and

0:37:59.000 --> 0:38:02.839
<v Speaker 8>clearly that has proven very problematic in twenty twenty three,

0:38:03.160 --> 0:38:04.960
<v Speaker 8>and so that'll be a huge question mark as we

0:38:05.040 --> 0:38:06.319
<v Speaker 8>go into twenty twenty four.

0:38:06.600 --> 0:38:07.200
<v Speaker 1>How much.

0:38:08.520 --> 0:38:12.279
<v Speaker 2>In terms of portfolio allocation? And I'm assuming you know, Aaron,

0:38:12.320 --> 0:38:14.640
<v Speaker 2>we've talked, you know, for a long time. You know,

0:38:14.719 --> 0:38:16.480
<v Speaker 2>you set things, and I'm assuming for a lot of

0:38:16.480 --> 0:38:22.000
<v Speaker 2>your clients it stays pretty consistent. But having said that,

0:38:22.040 --> 0:38:24.120
<v Speaker 2>I'm sure there are tweaks. Is there a tweak to

0:38:24.160 --> 0:38:26.120
<v Speaker 2>be made right now as we get ready to enter

0:38:26.120 --> 0:38:28.279
<v Speaker 2>a new year in your investment strategies?

0:38:28.920 --> 0:38:30.960
<v Speaker 8>Yeah, that's a good question, Carol. I mean, you're right,

0:38:31.000 --> 0:38:35.080
<v Speaker 8>we do care deeply about acid allocation, and thinking though

0:38:35.160 --> 0:38:38.279
<v Speaker 8>about the fundamentals of each ascid class does inform us

0:38:38.600 --> 0:38:41.680
<v Speaker 8>as to when we think a tilting may be warranted,

0:38:41.760 --> 0:38:44.600
<v Speaker 8>or even within an acid class an adjustment may be warranted.

0:38:44.680 --> 0:38:47.080
<v Speaker 8>So for example, even in fixed income, we went into

0:38:47.080 --> 0:38:51.160
<v Speaker 8>twenty twenty three and it looked like very short maturity

0:38:51.239 --> 0:38:54.960
<v Speaker 8>high yield was worth allocating to, even though the correlation

0:38:55.040 --> 0:38:57.400
<v Speaker 8>is high to the equity market and so on, the

0:38:57.480 --> 0:39:00.480
<v Speaker 8>margin became a little more constructive on how yield in

0:39:00.560 --> 0:39:04.040
<v Speaker 8>twenty three. In twenty four we have a similar posture

0:39:05.000 --> 0:39:08.480
<v Speaker 8>on that particular point because we don't see high yield

0:39:08.680 --> 0:39:13.520
<v Speaker 8>issuance for refinance occurring really into until twenty twenty five

0:39:13.560 --> 0:39:16.040
<v Speaker 8>and twenty six. Right about eight one point eight trillion

0:39:16.080 --> 0:39:19.040
<v Speaker 8>dollars of refise happening in high yield over the next

0:39:19.080 --> 0:39:22.560
<v Speaker 8>three years, but it's captured on the back end. But

0:39:22.680 --> 0:39:26.000
<v Speaker 8>maybe the most important point is ensuring that there is

0:39:26.080 --> 0:39:29.600
<v Speaker 8>ballast in the portfolio, particularly if economic growth declines and

0:39:29.719 --> 0:39:32.359
<v Speaker 8>disinflation continues. You want to ensure that you not only

0:39:32.400 --> 0:39:36.440
<v Speaker 8>have the treasuries and agency mortgage backed securities in our opinion,

0:39:36.800 --> 0:39:38.400
<v Speaker 8>but you want to make sure you have a sufficient

0:39:38.400 --> 0:39:41.800
<v Speaker 8>amount of duration to counteract what could be a weaker

0:39:41.880 --> 0:39:45.360
<v Speaker 8>equity market environment. And so you know, those slight adjustments

0:39:45.400 --> 0:39:49.279
<v Speaker 8>we're always thinking about making, obviously in conjunction with conversations

0:39:49.280 --> 0:39:51.000
<v Speaker 8>with clients and their liquidity needs.

0:39:51.040 --> 0:39:51.840
<v Speaker 6>And that sort of thing.

0:39:51.800 --> 0:39:53.960
<v Speaker 2>Well, certainly helpful as we get ready to close out

0:39:54.000 --> 0:39:56.360
<v Speaker 2>the year. Not sure we'll see before the end of

0:39:56.400 --> 0:39:58.800
<v Speaker 2>the year, but if we don't, happy holidays and happy

0:39:58.840 --> 0:40:02.640
<v Speaker 2>New Year. Aaron so appreciate it. Aaron Kennon, CEO and

0:40:02.680 --> 0:40:05.560
<v Speaker 2>co founder a Clear Harbor Asset Management, joining us on

0:40:05.680 --> 0:40:07.400
<v Speaker 2>Zoom from Stanford, Connecticut.

0:40:07.560 --> 0:40:12.200
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0:40:12.320 --> 0:40:16.040
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0:40:16.080 --> 0:40:19.680
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0:40:19.719 --> 0:40:23.040
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