WEBVTT - What's the Difference Between Aspirin, Ibuprofen, and Acetaminophen?

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<v Speaker 1>Welcome to brain Stuff production of iHeartRadio, Hey brain Stuff

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<v Speaker 1>Lauren vocal Bomb here. The average headache or backache often

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<v Speaker 1>sends people reaching willy nilly for the nearest bottle of

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<v Speaker 1>over the counter pain reliever, but for best results, it's

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<v Speaker 1>smart to match the particular problem with the particular pill.

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<v Speaker 1>That's because the wide variety of pain relievers, known in

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<v Speaker 1>medical circles as analgesis, available today, are each effective at

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<v Speaker 1>different problems and come with different risks. There are two

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<v Speaker 1>categories of pain pills suitable for home use, nonsteroidal anti

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<v Speaker 1>inflammatory drugs more commonly referred to as n SAIDs and

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<v Speaker 1>a staminafin Both are considered antipriretics, which means that they

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<v Speaker 1>can reduce fevers. Most people know a pseudominofin better by

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<v Speaker 1>the popular brand named Taylanol, but there are other brands

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<v Speaker 1>as well, like fever All. The category of n SAIDs

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<v Speaker 1>is broader. Things like aspirin, hypoprofen, and a proxin all

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<v Speaker 1>fall under the umbrella. There are others, but these three

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<v Speaker 1>are some of the most widely used. Each has its

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<v Speaker 1>own range of brand named versions, so which one is

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<v Speaker 1>best to use it all depends on what you're taking

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<v Speaker 1>it for. Stain, often sold under the brand name Talgenol,

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<v Speaker 1>was approved by the US Food and Drug Administration INE,

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<v Speaker 1>but how it works is still not clearly understood, but

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<v Speaker 1>we do know a bit about what it does. We

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<v Speaker 1>spoke via email with pharmacist Tara Thompson, doctor of pharmacy

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<v Speaker 1>and VP of Clinical Services at Innovation Compounding. She said

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<v Speaker 1>a stamina fin does not decrease inflammation, but works in

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<v Speaker 1>the hypothalamus to reduce fever, and it may work peripherally

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<v Speaker 1>to block the generation of pain. It's best taken to

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<v Speaker 1>reduce fever or symptoms of pain from flu like illnesses, headaches, arthritis,

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<v Speaker 1>and menstrual cramps, but note it will only mask the

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<v Speaker 1>pain without treating any underlying inflammation problems that cause some

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<v Speaker 1>of these symptoms. You should not take a seta mena

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<v Speaker 1>fin while consumer alcohol. It can be hard on the

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<v Speaker 1>liver even when your stone cold, sober, and much worse

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<v Speaker 1>when consuming alcohol. Most serious liver problems have been reported

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<v Speaker 1>following large doses. The highest amount that's considered safe is

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<v Speaker 1>three thousand, two hundred and fifty milligrams per day or

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<v Speaker 1>ten regular strength tablets. However, there have been instances when

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<v Speaker 1>liver damage occurs after medicating with moderate or even small

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<v Speaker 1>doses over a long period of time. Samina fin should

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<v Speaker 1>be taken carefully in conjunction with other medications. As many

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<v Speaker 1>headache and cold neds like Nike will already have seen

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<v Speaker 1>a man a fin in them. This can lead to

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<v Speaker 1>accidental overdoses. Anyone taking one of these extras should carefully

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<v Speaker 1>read labels and follow dosing instructions to the letter. It's

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<v Speaker 1>considered safe enough to take by just about anyone, but

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<v Speaker 1>occasionally side effects are experienced. Most often those are nausea, rash,

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<v Speaker 1>and headache, which is pretty ironic considering that that's why

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<v Speaker 1>many people take it in the first place. So that's

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<v Speaker 1>a stamina fin. Now let's talk about ncts. These are

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<v Speaker 1>so under brand names like Beyer, Advil, Motron, and a Leave.

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<v Speaker 1>You know how a stamtapin doesn't do a darn thing

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<v Speaker 1>to reduce inflammation well and said to pick up that

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<v Speaker 1>dropped ball and run all the way into the end

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<v Speaker 1>zone with it short for nonsteroidal anti inflammatory drugs. The

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<v Speaker 1>category of end SAIDs include a variety of analgesis like aspirin,

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<v Speaker 1>one brand name being bear I have a profen such

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<v Speaker 1>as ad villain, motron and an aproxin like a leave,

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<v Speaker 1>although there's some variation by particular type, and SAIDs in

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<v Speaker 1>general work by blocking the production of chemicals called prostaglandins,

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<v Speaker 1>which encourage fever, pain and inflammation. These effects can be

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<v Speaker 1>useful in promoting blood flow to an injured area and

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<v Speaker 1>in telling you to watch out and not further hurt

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<v Speaker 1>and injured area. But there's a point at which it's like, dude, body,

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<v Speaker 1>I know I shouldn't walk on that foot. You can

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<v Speaker 1>stop telling me so hard and SAIDs go out of

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<v Speaker 1>their way to denote non steroidal in the name because

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<v Speaker 1>steroids can also reduce inflammation, but the way steroids work

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<v Speaker 1>by depressing the immune system is a major distinction. So

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<v Speaker 1>when should you take end sids. Thompson said those with

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<v Speaker 1>inflammatory conditions such as osteoarthritis, rheumatoid arthritis, menstrual pain, or

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<v Speaker 1>muscular pain would benefit from an end said new proxyen

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<v Speaker 1>tends to work longer in the body, about two times longer,

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<v Speaker 1>so those with gout or more chronic pain conditions may

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<v Speaker 1>seem more pain relief from using new proxin versus iba

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<v Speaker 1>prove then, However, i've a proven provides quicker pain relief

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<v Speaker 1>than to proxin and is less likely to cause an

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<v Speaker 1>upset stomach, so might be more appropriate for strong and

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<v Speaker 1>sudden pain have a hangover, skip the staminafin in favor

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<v Speaker 1>of an end set. Although nothing short of time, rest

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<v Speaker 1>and lots of hydration can completely cure a hangover, the

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<v Speaker 1>anti inflammatory properties that end sets boast are believed to

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<v Speaker 1>be helpful. However, taking an end set on an upset stomach,

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<v Speaker 1>so common with hangovers, can make the discomfort worse, so

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<v Speaker 1>don't take it on an empty stomach well ever, but

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<v Speaker 1>especially in the case of hangovers. Aspirin has long been

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<v Speaker 1>used as a daily supplement of sorts for people at

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<v Speaker 1>risk of heart attack and stroke because it inhibits potentially

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<v Speaker 1>tragic blood clotting for roughly four to seven days. One

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<v Speaker 1>important caveat, however, is that people consuming aspirin for that

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<v Speaker 1>purpose should use a lower dosage under milligrams per day

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<v Speaker 1>than those using it for pain relief purposes. Thompson says

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<v Speaker 1>that aspirin is more commonly used nowadays for inhibiting blood

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<v Speaker 1>clotting than for relieving pain due to intestinal bleeding. Risks,

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<v Speaker 1>which brings us to when not to take them. Women

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<v Speaker 1>who are pregnant or trying to become pregnant are typically

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<v Speaker 1>advised to avoid use of end SAIDs because they're believed

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<v Speaker 1>to cause fertility issues, early miscarriage, and even birth defects.

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<v Speaker 1>In particular, they should not be taken in the third

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<v Speaker 1>trimester because they could cause premature closure of a particular

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<v Speaker 1>blood vessel and a developing baby. People of gastro intestinal

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<v Speaker 1>problems might also steer clear of end said use. Negative

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<v Speaker 1>gastro intestinal side effects like ulcers or intestinal bleeding can

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<v Speaker 1>occur because, as we said, prostaglandins aren't all bad. Preston

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<v Speaker 1>glanden's protect the stomach lining and help with blood clotting.

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<v Speaker 1>When those functions are inhibited, the risk of bleeding and

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<v Speaker 1>ulcers goes way up, Thompson said, although this is more

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<v Speaker 1>likely in those who take large doses for long periods

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<v Speaker 1>of time. Patients often turn to a seat a mena

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<v Speaker 1>fin from and SAIDs for pain relief since it does

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<v Speaker 1>not cause intestinal issues. Still confused about which to take,

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<v Speaker 1>talk to your doctor or the pharmacist at any local pharmacy.

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<v Speaker 1>They'll be able to make a recommendation and point you

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<v Speaker 1>towards the correct product. Today's episode was written by Ali A.

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<v Speaker 1>Hoyt and produced by Tyler Clanging. Brain Stuff is a

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<v Speaker 1>production of iHeart Radio's How Stuff Works from oneness and

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<v Speaker 1>lots of other helpful topics. Visit our home planet, how

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