Speaker 1: Welcome to brain Stuff production of iHeartRadio, Hey brain Stuff
Speaker 1: Lauren vocal Bomb here. The average headache or backache often
Speaker 1: sends people reaching willy nilly for the nearest bottle of
Speaker 1: over the counter pain reliever, but for best results, it's
Speaker 1: smart to match the particular problem with the particular pill.
Speaker 1: That's because the wide variety of pain relievers, known in
Speaker 1: medical circles as analgesis, available today, are each effective at
Speaker 1: different problems and come with different risks. There are two
Speaker 1: categories of pain pills suitable for home use, nonsteroidal anti
Speaker 1: inflammatory drugs more commonly referred to as n SAIDs and
Speaker 1: a staminafin Both are considered antipriretics, which means that they
Speaker 1: can reduce fevers. Most people know a pseudominofin better by
Speaker 1: the popular brand named Taylanol, but there are other brands
Speaker 1: as well, like fever All. The category of n SAIDs
Speaker 1: is broader. Things like aspirin, hypoprofen, and a proxin all
Speaker 1: fall under the umbrella. There are others, but these three
Speaker 1: are some of the most widely used. Each has its
Speaker 1: own range of brand named versions, so which one is
Speaker 1: best to use it all depends on what you're taking
Speaker 1: it for. Stain, often sold under the brand name Talgenol,
Speaker 1: was approved by the US Food and Drug Administration INE,
Speaker 1: but how it works is still not clearly understood, but
Speaker 1: we do know a bit about what it does. We
Speaker 1: spoke via email with pharmacist Tara Thompson, doctor of pharmacy
Speaker 1: and VP of Clinical Services at Innovation Compounding. She said
Speaker 1: a stamina fin does not decrease inflammation, but works in
Speaker 1: the hypothalamus to reduce fever, and it may work peripherally
Speaker 1: to block the generation of pain. It's best taken to
Speaker 1: reduce fever or symptoms of pain from flu like illnesses, headaches, arthritis,
Speaker 1: and menstrual cramps, but note it will only mask the
Speaker 1: pain without treating any underlying inflammation problems that cause some
Speaker 1: of these symptoms. You should not take a seta mena
Speaker 1: fin while consumer alcohol. It can be hard on the
Speaker 1: liver even when your stone cold, sober, and much worse
Speaker 1: when consuming alcohol. Most serious liver problems have been reported
Speaker 1: following large doses. The highest amount that's considered safe is
Speaker 1: three thousand, two hundred and fifty milligrams per day or
Speaker 1: ten regular strength tablets. However, there have been instances when
Speaker 1: liver damage occurs after medicating with moderate or even small
Speaker 1: doses over a long period of time. Samina fin should
Speaker 1: be taken carefully in conjunction with other medications. As many
Speaker 1: headache and cold neds like Nike will already have seen
Speaker 1: a man a fin in them. This can lead to
Speaker 1: accidental overdoses. Anyone taking one of these extras should carefully
Speaker 1: read labels and follow dosing instructions to the letter. It's
Speaker 1: considered safe enough to take by just about anyone, but
Speaker 1: occasionally side effects are experienced. Most often those are nausea, rash,
Speaker 1: and headache, which is pretty ironic considering that that's why
Speaker 1: many people take it in the first place. So that's
Speaker 1: a stamina fin. Now let's talk about ncts. These are
Speaker 1: so under brand names like Beyer, Advil, Motron, and a Leave.
Speaker 1: You know how a stamtapin doesn't do a darn thing
Speaker 1: to reduce inflammation well and said to pick up that
Speaker 1: dropped ball and run all the way into the end
Speaker 1: zone with it short for nonsteroidal anti inflammatory drugs. The
Speaker 1: category of end SAIDs include a variety of analgesis like aspirin,
Speaker 1: one brand name being bear I have a profen such
Speaker 1: as ad villain, motron and an aproxin like a leave,
Speaker 1: although there's some variation by particular type, and SAIDs in
Speaker 1: general work by blocking the production of chemicals called prostaglandins,
Speaker 1: which encourage fever, pain and inflammation. These effects can be
Speaker 1: useful in promoting blood flow to an injured area and
Speaker 1: in telling you to watch out and not further hurt
Speaker 1: and injured area. But there's a point at which it's like, dude, body,
Speaker 1: I know I shouldn't walk on that foot. You can
Speaker 1: stop telling me so hard and SAIDs go out of
Speaker 1: their way to denote non steroidal in the name because
Speaker 1: steroids can also reduce inflammation, but the way steroids work
Speaker 1: by depressing the immune system is a major distinction. So
Speaker 1: when should you take end sids. Thompson said those with
Speaker 1: inflammatory conditions such as osteoarthritis, rheumatoid arthritis, menstrual pain, or
Speaker 1: muscular pain would benefit from an end said new proxyen
Speaker 1: tends to work longer in the body, about two times longer,
Speaker 1: so those with gout or more chronic pain conditions may
Speaker 1: seem more pain relief from using new proxin versus iba
Speaker 1: prove then, However, i've a proven provides quicker pain relief
Speaker 1: than to proxin and is less likely to cause an
Speaker 1: upset stomach, so might be more appropriate for strong and
Speaker 1: sudden pain have a hangover, skip the staminafin in favor
Speaker 1: of an end set. Although nothing short of time, rest
Speaker 1: and lots of hydration can completely cure a hangover, the
Speaker 1: anti inflammatory properties that end sets boast are believed to
Speaker 1: be helpful. However, taking an end set on an upset stomach,
Speaker 1: so common with hangovers, can make the discomfort worse, so
Speaker 1: don't take it on an empty stomach well ever, but
Speaker 1: especially in the case of hangovers. Aspirin has long been
Speaker 1: used as a daily supplement of sorts for people at
Speaker 1: risk of heart attack and stroke because it inhibits potentially
Speaker 1: tragic blood clotting for roughly four to seven days. One
Speaker 1: important caveat, however, is that people consuming aspirin for that
Speaker 1: purpose should use a lower dosage under milligrams per day
Speaker 1: than those using it for pain relief purposes. Thompson says
Speaker 1: that aspirin is more commonly used nowadays for inhibiting blood
Speaker 1: clotting than for relieving pain due to intestinal bleeding. Risks,
Speaker 1: which brings us to when not to take them. Women
Speaker 1: who are pregnant or trying to become pregnant are typically
Speaker 1: advised to avoid use of end SAIDs because they're believed
Speaker 1: to cause fertility issues, early miscarriage, and even birth defects.
Speaker 1: In particular, they should not be taken in the third
Speaker 1: trimester because they could cause premature closure of a particular
Speaker 1: blood vessel and a developing baby. People of gastro intestinal
Speaker 1: problems might also steer clear of end said use. Negative
Speaker 1: gastro intestinal side effects like ulcers or intestinal bleeding can
Speaker 1: occur because, as we said, prostaglandins aren't all bad. Preston
Speaker 1: glanden's protect the stomach lining and help with blood clotting.
Speaker 1: When those functions are inhibited, the risk of bleeding and
Speaker 1: ulcers goes way up, Thompson said, although this is more
Speaker 1: likely in those who take large doses for long periods
Speaker 1: of time. Patients often turn to a seat a mena
Speaker 1: fin from and SAIDs for pain relief since it does
Speaker 1: not cause intestinal issues. Still confused about which to take,
Speaker 1: talk to your doctor or the pharmacist at any local pharmacy.
Speaker 1: They'll be able to make a recommendation and point you
Speaker 1: towards the correct product. Today's episode was written by Ali A.
Speaker 1: Hoyt and produced by Tyler Clanging. Brain Stuff is a
Speaker 1: production of iHeart Radio's How Stuff Works from oneness and
Speaker 1: lots of other helpful topics. Visit our home planet, how
Speaker 1: stuff Works dot com, and for more podcasts from my
Speaker 1: heart Radio, visit the iHeart Radio app, Apple Podcasts, or
Speaker 1: wherever you listen to your favorite shows.