Speaker 1: Really now, really.
Speaker 2: Really now, really well and welcome to really know really
Speaker 2: with Jason Alexander and Peter Tilden. He remind you that
Speaker 2: subscribing to our show gives many listeners they sustained and
Speaker 2: euphoric high and speaking of getting high.
Speaker 3: As of November twenty.
Speaker 2: Twenty four, recreational cannabis is legal in twenty four states
Speaker 2: and is available medically and or decriminalized in an additional
Speaker 2: twenty Clearly, the floodgates have opened and the normalization of
Speaker 2: marijuana's positive benefits has taken hold.
Speaker 3: But what do we really know about the effects of potts?
Speaker 2: Is there science based evidence demonstrating what happens after long
Speaker 2: term consumption? Is it true that teen emergency room visits
Speaker 2: are up, suicides and psychotic episodes are up, and that
Speaker 2: schizophrenia may perhaps be linked to cannabis? These questions became
Speaker 2: very personal for us here really know really when co
Speaker 2: host Peter Tilden realized he had become addicted to cannabis
Speaker 2: during the pandemic. Struggled to stop, and so doctor Bertha Madras,
Speaker 2: the director of the Laboratory of Addiction Neurobiology at McLean Hospital,
Speaker 2: Professor of Psychobiology, at Harvard Medical School and one of
Speaker 2: the nation's leading experts on marijuana, came by to answer
Speaker 2: all of Peter and Jason's questions.
Speaker 3: And if you smoke weed or know someone who.
Speaker 2: Does, you may be surprised and shocked by what you're
Speaker 2: about to find out.
Speaker 3: Really, no, really, here's Jason and Peter.
Speaker 1: Good Hello, Hello to you, sir.
Speaker 4: You must say good morning, and you finally right because
Speaker 4: I realize people, yeah, they also I also know this.
Speaker 5: This is what I've learned after listening to our podcast
Speaker 5: for whether we got eighty five in?
Speaker 1: Ready, can I anticipate what you're gonna say?
Speaker 4: Yeah, this will be edited, that's right, So saying it
Speaker 4: doesn't matter because no one's hearing.
Speaker 5: We spend minutes doing glorious repartee winds up on somebody's floor.
Speaker 1: You know, we should do glory cuts it right in.
Speaker 1: We should do an entireties whatever.
Speaker 5: It is she's against it, and that you insert it
Speaker 5: and that way, that's the only way this repartee will
Speaker 5: be in the show.
Speaker 1: We should do a very special episode that's just cut
Speaker 1: together all the openings, every opening.
Speaker 5: So here's here's my question to you as we start
Speaker 5: this episode today about I'm estimating I've lost all sense
Speaker 5: of time, but three months ago, maybe a little more.
Speaker 5: You hold turkey, you're a marijuana use. You're off, you're done,
Speaker 5: You're out.
Speaker 4: To be totally honest. Yeah, I slipped a couple of
Speaker 4: times and was upset that I did under ten circumstances, situation,
Speaker 4: some stuff.
Speaker 1: Yeah, but yeah, I'm out. I'm out. Okay.
Speaker 5: First of all, how was it? How was it getting off?
Speaker 5: It's still difficult, still difficult in what way?
Speaker 1: It was a crutch.
Speaker 4: You use it as a crutch, and it helps you
Speaker 4: get through the day because you don't have to you
Speaker 4: don't have to deal with the stuff that you should
Speaker 4: be dealing with. Because it puts you you can nap,
Speaker 4: puts you out, You feel a little bit better. The
Speaker 4: problem was I was doing it so much that it
Speaker 4: was acting not to help me. It was making me nervous.
Speaker 4: It was making me jittery, which which was the beginning
Speaker 4: of the reason for this episode.
Speaker 1: Right, we had somebody on because it was not going
Speaker 1: to come for me.
Speaker 5: I'm you know, except for when I drove with a
Speaker 5: trunk full of marijuana that could land me in a
Speaker 5: federal one.
Speaker 4: Early guests, But what I started realizing, is that the
Speaker 4: floodgates have open and they're legalizing this, and as use
Speaker 4: goes up, the perception of harmfulness decreases.
Speaker 1: So it becomes it becomes normalized.
Speaker 4: Yeah, And I wondered, because this shows really not really
Speaker 4: is there any evidence backed science to this. So I
Speaker 4: reached out to one of the nation's top experts on marijuana.
Speaker 4: Because you keep hearing reports on emergency room visits, especially
Speaker 4: by teens is way through the roof dichotic episodes, schizophrenia.
Speaker 4: They don't know what THHC long term can do to
Speaker 4: you all kinds of other repercussions. So I want to go,
Speaker 4: wait a minute, we should at least know. I'm not
Speaker 4: saying you should stop, not stop. I just would like
Speaker 4: to know.
Speaker 5: We don't proselytize no, we don't preach no, which is
Speaker 5: the same thing.
Speaker 1: By the way, proselytizing and.
Speaker 4: Preaching don't be condescending, which means to talk down to
Speaker 4: So I wanted to get an expert on to get
Speaker 4: science based knowledge to go, what what do we know
Speaker 4: about marijuana at this point and what should be concerned about?
Speaker 1: That's all you just want to know if you can
Speaker 1: go back. That's what I think part of the part
Speaker 1: of the big, big part of that back a little bit.
Speaker 5: She opens's what's the you know what is the teter totter?
Speaker 1: How much before I start to flag goes down? If
Speaker 1: she says go for it.
Speaker 5: Yeah, So and you realize this is I am a
Speaker 5: complete non user because I'm allergic to it.
Speaker 1: What do you get when you smoke?
Speaker 5: I had two experiences in high school when you're first
Speaker 5: introduced to this stuff. The first time I got I
Speaker 5: don't get migrants, but I got what I assume is
Speaker 5: like a migraine like headache and hives. I broke out
Speaker 5: in hives, and I went, oh, this is awful. I'm
Speaker 5: never doing that again. Went to another party a couple
Speaker 5: months later and somebody was passing a joint and I
Speaker 5: don't think this is I get a thing from this,
Speaker 5: and they went, oh, no, that was bad stuff.
Speaker 1: This is the good that's the other thing. This is
Speaker 1: the good stuff.
Speaker 5: So I tried this one and worse, worse, migraine, more hives,
Speaker 5: and I went, it's a plant.
Speaker 1: I'm allergic to a lot of plans.
Speaker 4: We want to know what the scientists, so hopefully definitive
Speaker 4: today we will at least explore the reality of what
Speaker 4: they know. Research was right about the positives of pot
Speaker 4: if they can measure them. I mean, when you have
Speaker 4: a migraine, does a doctor go two joints of sativa?
Speaker 1: Five hits and three hail marys? Yeah, I'm with you totally.
Speaker 1: So let's find so, let's find out who our guests today.
Speaker 1: Shall we introduce her?
Speaker 5: Why wouldn't we? Why wouldn't we? So you're more familiar
Speaker 5: with this lady than I am. I just love her name,
Speaker 5: doctor Bertha. I love that name, Doctor Bertha Mandras. Do
Speaker 5: a strength, say it loud.
Speaker 1: And it's almost like praying, we can't afford that. I
Speaker 1: know that, And it's almost like saying.
Speaker 4: She's a director of the Laboratory of Addiction Neurobiology at
Speaker 4: McLean Hospital and is professor of psychobiology at Harvard Medical School,
Speaker 4: and she's considered one of the premier leading experts on marijuana.
Speaker 5: Well, let's get high and welcome doctor Bertha Madras.
Speaker 1: Hello, doctor Madras.
Speaker 6: Hello, Hello, greetings, tool, thank you.
Speaker 5: Welcome to really know really where Peter is not stoned?
Speaker 5: And I'm not sure if you even would rather be
Speaker 5: at this point.
Speaker 4: Peter well, again, I really was truly addicted to marijuana.
Speaker 4: We've talked about this that I would do it to
Speaker 4: go to The setup was I'm doing this to go
Speaker 4: to sleep. Yeah, then it's I'm doing it dinner time.
Speaker 4: Then I'm doing it at lunchtime. Then I'm doing it
Speaker 4: to kind of dull out any aggravation that I have
Speaker 4: to do.
Speaker 5: You're basically explaining how I use cake exactly the same thing.
Speaker 4: So why don't we turn it over to you? Because
Speaker 4: you've researched it. What have you found? What do we know?
Speaker 1: What do we know for sure?
Speaker 6: Well, first of all, the first myth that I would
Speaker 6: love people to hear about is it's only a plant.
Speaker 6: That's what you hear commonly among kids, among users and
Speaker 6: saying it's nature's own sedative, it's nature's own sleep medicine,
Speaker 6: it's nature's own So let me just give you a
Speaker 6: little bit of background. They're over three hundred thousand plants
Speaker 6: on this earth, and humans consume only about three hundred
Speaker 6: of those three hundred thousand. And the reason we consume
Speaker 6: only a few of the many that we have a
Speaker 6: choice is because most plants are poisonous to human beings.
Speaker 6: Why is that the case is because plants don't have teeth,
Speaker 6: they don't have fists, they don't have legs to run away,
Speaker 6: they have no protection, so they produce substances that can
Speaker 6: disable the people, the humans, the animals, and the insects
Speaker 6: that consume them. Now, marijuana happens to have in it
Speaker 6: THHC delta nine tetrahydrocannabinol, which is a psychoactive compound that
Speaker 6: interferes with normal brain communication. And it is likely, because
Speaker 6: an experiment was done recently in India, it is likely
Speaker 6: that the plant uses THHC to interfere with the nervous
Speaker 6: system of things that consume it, and so it is
Speaker 6: probably one of marijuana's protective factors. Wow, it's as simple
Speaker 6: as that. Now, the thing that I would love to
Speaker 6: emphasize here is the number of parents, the number of
Speaker 6: young people, adolescents, young adults that have told me over
Speaker 6: and over again, if only I knew before they went
Speaker 6: down the path that led them to addiction, psychosis, loss
Speaker 6: of motivation. I can go on and on.
Speaker 4: All right, So let's talk about the medicinal benefits. Do
Speaker 4: we know scientifically? Do we know long term effects?
Speaker 5: So if there are definitive positive uses for marijuana.
Speaker 6: Okay, so there are no definitive studies that provide evidence
Speaker 6: that marijuana the smoke plant has any strong medicinal benefits period.
Speaker 6: All the meta analyzes, all the papers say that it
Speaker 6: may be a mild pain reducing substance. It may induce sleep,
Speaker 6: but it also could promote sleep disorders eventually with chronic use,
Speaker 6: and so on and so forth. It may prevent vomiting,
Speaker 6: but after very high dose frequent use, it can promote vomiting.
Speaker 6: Cannabis hyper emesis syndrome is not frequent, but people have
Speaker 6: these symptoms. They have to go to emergency departments. They
Speaker 6: have to take hot showers to get rid of them.
Speaker 6: Almost every therapeutic benefit that has been touted for marijuana,
Speaker 6: first of all, does not have potent, high quality signs
Speaker 6: behind it. And alternatives exist that are generally safer than marijuana.
Speaker 5: And doctor Anders, does that include the reported pain relief
Speaker 5: benefits of use.
Speaker 6: The reported pain reliefs We don't even have side by
Speaker 6: side comparisons with over the counter medications like ibuprofen or
Speaker 6: other non steroid lantine flammatories. But marijuana is a very
Speaker 6: mild pain reducing substance, and people began to promote it
Speaker 6: in the early twenty twenty twenties as a substitute for
Speaker 6: the opioid crisis, and that was pure, pure fiction. It
Speaker 6: does not substitute for opiods. It cannot reduce pain to
Speaker 6: the extent that opioids do, and the alternatives that are
Speaker 6: over the counter are much safe.
Speaker 4: Alcohol metabolize a certain way in the system. Does how
Speaker 4: does THC or And when I say TFC, I understand
Speaker 4: there are like three hundred chemicals in marijuana if you
Speaker 4: can address that, but how does it metabolize? What happens
Speaker 4: when somebody takes it in as a posed alcohol the
Speaker 4: comparison there.
Speaker 6: There are over seven hundred chemicals in the marijuana plant
Speaker 6: and over one hundred and seven cannabinoids that the marijuana
Speaker 6: plant produces. The primary ones are THHC and cannabidiol. When
Speaker 6: a person consumes marijuana, the the thing you have to
Speaker 6: know is the chemistry of THHC is completely different than alcohol.
Speaker 6: Alcohol is a substance that dissolves in fat. It dissolves
Speaker 6: in water, so within one to two hours, depending on
Speaker 6: what you've eaten, alcohol clears from the body. So one
Speaker 6: during per hour, one drink every two hours, and the
Speaker 6: effects are gone. Because marijuana's chemistry is such that it's
Speaker 6: very fatty. It loves to stick in fat, it dissolves
Speaker 6: in fat. The brain is a fatty organ The brain
Speaker 6: uses fats to insulate its wires so that it doesn't
Speaker 6: get wiring mixed up. Marijuana accumulates in the brain and
Speaker 6: it can last for at least eight to twenty four
Speaker 6: hours before it clears entirely. Heavy users you can still
Speaker 6: detect THHC in their blood after three to four weeks
Speaker 6: because it's going to be absorbed by the fat and
Speaker 6: it'll be slowly, slowly leached out.
Speaker 4: Well, and now you said there's seven hundred chemicals in
Speaker 4: the plant. Yes, And it was wondering with today's regulations.
Speaker 4: Is it regulated to the point that when you go
Speaker 4: to a dispensary and you buy something that you know
Speaker 4: that there's some kind of quality assurance to it or
Speaker 4: is that complete nonsense?
Speaker 1: Does that mean nothing still the wild West?
Speaker 6: Complete nonsense? There are regulations in place, for example, in California,
Speaker 6: where you are somebody. A study was just done analyzing
Speaker 6: samples of marijuana from dispensaries. They found pesticide they found her. Besides,
Speaker 6: they've found all kinds of junk in the marijuana, and
Speaker 6: they and other studies have shown that the PERCENTHC that's
Speaker 6: on the labels is completely fiction. In some cases, it's
Speaker 6: very very rarely accurate. It's either they either toute that
Speaker 6: it has more THHC than the present or much less
Speaker 6: thchc than it's actually present in what you buy. The
Speaker 6: regulations are sound ideal, they're fictitious in terms of reduced
Speaker 6: to practice, costs a lot of money to analyze every dispensary,
Speaker 6: every sample, and a lot of states are not doing
Speaker 6: due diligence.
Speaker 5: So dog I wanted to ask a question in regard
Speaker 5: to the addictiveness of this how addictive or not is
Speaker 5: this substance?
Speaker 7: Well, it's very interesting and I'm smiling because the statistics
Speaker 7: are coming out now that are so I mean, they're
Speaker 7: almost astonishing, but for me they probably shouldn't be. Right now,
Speaker 7: some of the best epidemiologists in the country have reported
Speaker 7: that twenty nine percent of people who use marijuana, either
Speaker 7: for recreational purposes or for medical purposes, have a cannabis
Speaker 7: use disorder.
Speaker 6: A third of the people. Now, why is that so
Speaker 6: because people using it for so called medicinal purposes are
Speaker 6: using daily or five times daily or ten times daily.
Speaker 6: And the risks of becoming addicted to marijuana increase depending
Speaker 6: on how frequently you use. So if you use daily,
Speaker 6: the risks are about thirty to fifty percent.
Speaker 5: And when you have this condition that you're addicted to it,
Speaker 5: what are the signs of that?
Speaker 1: What are the symptoms of that?
Speaker 6: Well, the symptoms are standard symptoms for use disorder substance disorders.
Speaker 6: It means not meeting commitments. It means being disinterested in
Speaker 6: in uh in things and things that you normally are.
Speaker 6: It means trying to quit and being unable to quit frequently.
Speaker 6: There are eleven criteria for for substance use disorders. The
Speaker 6: interesting thing is somebody in UH in the National Survey
Speaker 6: and Drug Use in Health compared the symptoms of alcohol
Speaker 6: used disorder with cannabis use disorder and they've found that
Speaker 6: the symptoms that are categorized as more moderate in this
Speaker 6: moderate to severe category are higher for marijuana than for alcohol.
Speaker 6: And alcohol there are more numbers of people in the
Speaker 6: mild to moderate range.
Speaker 4: Wow, So when I used it and was really using
Speaker 4: it a lot, I started having anxiety, I started to
Speaker 4: have disinterest. I started also aggression, like I would snap.
Speaker 4: My personality change. And now I hear that er visits
Speaker 4: are up, especially among young people with psychosis suicidal planning.
Speaker 4: I mean that is that accurate? And to what extent
Speaker 4: what percentage of marijuanas can be attributed to that?
Speaker 6: Well, psychosis has been a very controversial issue until I
Speaker 6: think the data that has come in in the past
Speaker 6: ten years. So psychosis, as you know, there's there's many
Speaker 6: causes of psychosis. Some of them are and some of
Speaker 6: them could be metabolic, some are drug induced, and so on.
Speaker 6: But the association between psychosis, schizophrenia which means an enduring psychosis,
Speaker 6: and marijuana is getting so strong that more and more
Speaker 6: people are claiming that it's a cause of schizophrenia, not
Speaker 6: just an association. That's right, And why is that? First
Speaker 6: of all, it's dose response. The more you use, the
Speaker 6: more frequently you use, the more likely you have to
Speaker 6: develop schizophrenia. Secondly, in seven countries at least where they
Speaker 6: have looked at people with early onset marijuana use, the
Speaker 6: risks of developing schizophrenia are higher that if you never
Speaker 6: touched marijuana during your young young adolescent or a young adult. So,
Speaker 6: and there's a six criteria for causality and marijuana, I
Speaker 6: think fulfills at least five of those.
Speaker 1: Do you guys?
Speaker 4: As I'm listening to this, all I'm hearing is like
Speaker 4: from my past of bringing this stuff up. Oh, these
Speaker 4: guys have an agenda. They went into this for a reason.
Speaker 4: Did you get into this one any kind of agenda?
Speaker 1: Number one?
Speaker 4: And number two? What kind ofushback do you get? Because
Speaker 4: you must get pushback.
Speaker 6: So, first of all, agenda, I am not a drug user.
Speaker 6: I don't use alcohol. It's not that I have an
Speaker 6: aversion to alcohol. It's that I simply don't. I just
Speaker 6: fall asleep with it. So there's no point in missing
Speaker 6: the party if you're going to go to sleep, right.
Speaker 6: I have always observed when I was a kid, I
Speaker 6: observed what happens to people using drugs. And in my childhood,
Speaker 6: which was one hundred years ago, we had one or
Speaker 6: two kids who started using marijuana and they went downhill
Speaker 6: very fast, and I was stunned by that. That didn't
Speaker 6: inject into me a passion about it until I was
Speaker 6: a graduate student and I started to I was asked
Speaker 6: to try to find out how LSD works, and I
Speaker 6: started to read the literature on psychiatry uses of LSD,
Speaker 6: and they were malevolent the effects of LSD, And gradually
Speaker 6: I became more and more interested in trying to protect
Speaker 6: the human brain. My real passion is the magnificence of
Speaker 6: the human brain. It's the one thing that makes us human.
Speaker 6: It's the repository of our humanity, and drugs can interfere
Speaker 6: with normal human brain function and derail people's potential. That
Speaker 6: became my motivation, and after that I volunteered. I am
Speaker 6: not in the payroll of anyone whatsoever.
Speaker 1: So what about the pushback.
Speaker 6: The pushback I've received?
Speaker 1: So what about the pushback.
Speaker 6: The push back I've received? Obviously, the drug policy alliance
Speaker 6: of people who are users, reporters and the media who
Speaker 6: are users. Many people who use casually have no consequences,
Speaker 6: and so they say, because I personally have no consequences,
Speaker 6: there is nothing wrong with the drug. That's not how
Speaker 6: science works. Science works on the basis of epidemiology. They
Speaker 6: look at vast numbers of people. They look at the
Speaker 6: consequences to vast numbers of people, not to individuals. That's
Speaker 6: how the FDA works when it approves drugs. It doesn't
Speaker 6: go up to a person with a microphone and interviews
Speaker 6: them and says, did marijuana make you feel good? And
Speaker 6: did it reduce your pain? Okay, then will approve it. No,
Speaker 6: it works on the basis of statistics and vast numbers
Speaker 6: of people. And so the science is on the side
Speaker 6: of what I'm saying. Because I'm just quoting manuscript after manuscript,
Speaker 6: each one of which I can send you the citations, right,
Speaker 6: but I've had pushback. It doesn't bother me because basically
Speaker 6: my foundation, my base is data, and the data disclaims
Speaker 6: some of the folks who are heavy lifetime users.
Speaker 5: What I'm hearing anecdotally from people now, both users and
Speaker 5: people in your profession. The catchphrase is, you know, the
Speaker 5: pot today is not your grandfather's pot. Are growers and
Speaker 5: distributors actually trying to grow more powerful strains of marijuana?
Speaker 1: Why has it become so much more it's.
Speaker 6: Much more powerful? Of course they are.
Speaker 1: You know.
Speaker 6: There's a very well known principle in biology that the
Speaker 6: faster a drug gets into the brain and stronger the hit,
Speaker 6: meaning the higher the dose, the addictive potential goes up.
Speaker 6: Now everybody in drug industry, alcohol, tobacco, marijuana, they all
Speaker 6: know a verius and cocaine opioids. They know a very
Speaker 6: simple principle. The more powerful the drug, the more you
Speaker 6: get people addicted. The more people are addicted, the more
Speaker 6: you have a cache of people who are chronic users,
Speaker 6: who are going to be your main source of profit.
Speaker 6: And that's basically what it is. So in the sixties
Speaker 6: and seventies, the concentration of THHC in the marijuana plant
Speaker 6: was anywhere from believe it or not, as low as
Speaker 6: one percent up to four or five percent with hashiesh
Speaker 6: it is now bred to be about twenty percent THC
Speaker 6: and dabs and shatters, which is an increasing market share,
Speaker 6: which is highly concentrated THHC can be up to ninety
Speaker 6: percent THC.
Speaker 5: I just want to ask you about the other popular
Speaker 5: component of marijuana, CBD. Are there similar Are there? There
Speaker 5: seems to be in cosmetics and sleep aids and different
Speaker 5: kinds of things pain relief, topical pain relief. Is CBD
Speaker 5: a different story altogether or or there are also problems
Speaker 5: with that.
Speaker 6: CBD is an entirely different story in terms of it
Speaker 6: is non addictive, It does not have psychoactive properties. It
Speaker 6: does not intoxicate you. It functions in ways that are cryptic.
Speaker 6: People really don't quite know how it works. From that
Speaker 6: point of view, it's much safer. The problem with CBD
Speaker 6: is that it can also have drug interactions with other
Speaker 6: medications that you take. That's a problem, and there is
Speaker 6: some evidence of liver toxicity. The thing that is really
Speaker 6: disconcerting is that it's being marketed under false premises because
Speaker 6: there is a claim that it is a painkiller. The
Speaker 6: evidence is very weak. There's a claim that it puts
Speaker 6: you to sleep. The evidence is very weak. It can
Speaker 6: be sedating, but it's not a good sleep aid. And
Speaker 6: yet it seems to have taken hold. People are buying
Speaker 6: it like the droves and making all kinds of claims
Speaker 6: that have no basis in science.
Speaker 4: Are you completely disconcerted about the fact that the ship
Speaker 4: has sailed? Do you feel like there's that we can't
Speaker 4: take it back, that we don't have long term studies?
Speaker 1: Where are we? Where are we as far as regulation,
Speaker 1: as far as getting the information out in the right way.
Speaker 6: Well, there are three things to say about that. Number
Speaker 6: one is there is beginning to be pushback and for
Speaker 6: the first time. The New York Times, which has been
Speaker 6: touting marijuana much of the mainstream media, has promoted the
Speaker 6: drug is safe, non addictive, and effective. For the first time,
Speaker 6: you're beginning to see articles the mainstream media that are
Speaker 6: that are beginning to describe the negative effects of marijuana.
Speaker 6: Second thing we have to say is that given the
Speaker 6: tobacco and alcohol industry is a model, once you have
Speaker 6: massive dollars involved, billions of dollars that go into campaign
Speaker 6: coffers of politicians, it's very hard to reverse a movement
Speaker 6: because there's so much money involved. I'm very concerned learned
Speaker 6: about that. I would love to see a reversal of
Speaker 6: the mess we've made with marijuana, conflating it with medicine
Speaker 6: and recreation. We've eroded the FDA, We've done everything wrong
Speaker 6: in our country with regard to how we've handled this drug.
Speaker 6: The third issue that I'm worried about is that the
Speaker 6: same playbook that has been used for marijuana is being
Speaker 6: used for hallucinogen psychedelics. And I'm extremely worried about that
Speaker 6: because i know what happened to a lot of people
Speaker 6: in the nineteen sixties and seventies, and I'm praying that
Speaker 6: it doesn't happen again.
Speaker 1: If you're having to use it.
Speaker 5: Is there a benefit to edibles rather than smoking the edibles?
Speaker 6: There's different reasons for people going into emergency rooms with
Speaker 6: edibles versus smokeables. And because the edibles don't kick in
Speaker 6: until a few hours, because it takes long for digestion
Speaker 6: to absorb the thh scene, they get it into the
Speaker 6: partiovascular system. We are seeing more cases of edibles giving
Speaker 6: rise to different types of problems than smoking. Smoking is
Speaker 6: associated more with psychosis. Edibles are associated more with other
Speaker 6: types of symptoms and emergency departments.
Speaker 1: And secondhand exposure.
Speaker 5: I'm a complete non user, so when I'm around people
Speaker 5: using it, or I'm in a club or a stadium,
Speaker 5: how much am I being affected by it?
Speaker 6: Well, there's some evidence that secondhand smoke can get into
Speaker 6: your blood system and give you a positive The evidence
Speaker 6: on whether or not it becomes intoxicating or not is
Speaker 6: not as robust unless you're sitting in a car and
Speaker 6: just everybody is smoking it and you're not where the smoke.
Speaker 1: Density is very high.
Speaker 6: But I would say the evidence still is not robust
Speaker 6: enough to make claims.
Speaker 5: All right, last question for me solve my teenage mystery.
Speaker 5: I've tried marijuana twice when I was a teenager back
Speaker 5: in the seventies. Each time I got a migraine in hives.
Speaker 5: Does that mean I'm allergic to the plant.
Speaker 6: It's hard to know, but you may be allergic to
Speaker 6: the fun guys that were growing on it.
Speaker 1: Here you go, Just don't use it. Just say no,
Speaker 1: Just say no to hive. Hey, you're not the boss
Speaker 1: of me. And by the way, you're riding with Cheech
Speaker 1: and Chong in a car. Yes, I'm going to get
Speaker 1: at the secondhand.
Speaker 4: Doctor Matters, Thank you so much. And by the way,
Speaker 4: today you can google her and see the papers and
Speaker 4: see her talked on this and get some other information
Speaker 4: that maybe we didn't get. But I just thought it
Speaker 4: was important and I will probably get a lot of pushback,
Speaker 4: but I just wanted to know the science, the science
Speaker 4: behind this.
Speaker 6: There's one more science that I didn't mention that i'd
Speaker 6: left to before I sure run off. This was just
Speaker 6: published this week.
Speaker 3: Now.
Speaker 6: I've been saying this for at least fifteen years because
Speaker 6: of some of the scientific papers that are coming out.
Speaker 6: But now someone did what's called a meta analysis. They
Speaker 6: accumulated all the papers on this particular topic that included
Speaker 6: one hundred thousand adolescents, and they found what I've been
Speaker 6: saying for fifteen years. Raids are lower. Dropout rates in
Speaker 6: high school are much higher. College applications, college entries, college
Speaker 6: completions are all much lower. On kids who use marijuana
Speaker 6: in high school, their whole academic future is very much
Speaker 6: compromised by using marijuana in high school.
Speaker 1: Wow.
Speaker 4: Not a great statistic. Well, thank you for coming on.
Speaker 4: Oh my gosh, we appreciate it your time. And by
Speaker 4: the way, mostly I might say, you have a lovely family, lovely, lovely.
Speaker 3: Oh my god, they'll kill me.
Speaker 4: They'll he'll be thrilled. Thank you so much again, thanks
Speaker 4: for your time. I know how busy you are.
Speaker 3: Carefull that.
Speaker 5: So two things I know. One is I'm much healthier
Speaker 5: than you because my brain is fine. So whenever we
Speaker 5: have a discussion, I win because my brain is healthier,
Speaker 5: my body is healthier. That's the first thing agreed.
Speaker 4: Are we agreed on that you have so many other
Speaker 4: problems rather than the smoking. My brain is healthier.
Speaker 1: No, my brain is healthier, my body is healthy.
Speaker 4: It's based on the fact that you don't do pot.
Speaker 4: My brain is healthier, I'm smarter, I'm more vigorous. Yes,
Speaker 4: good luck. Okay, you know what, you live in a
Speaker 4: delusional world. God bless you.
Speaker 5: Second thing, we know she's got a lovely home. We
Speaker 5: saw so many things and then we started in the
Speaker 5: upstairs that was no good. Then we moved into the
Speaker 5: sunniest sun room I've ever seen. It looked like like,
Speaker 5: you know, the Messiah was rising behind her.
Speaker 4: Not doing drugs helps you with thing schweish you had
Speaker 4: a beautiful.
Speaker 5: Beautiful And then we went over and as you say,
Speaker 5: a lovely family, my.
Speaker 1: Family, which means a lot. By the way, nobody that
Speaker 1: family had their hairspe.
Speaker 5: And I'll tell you something else. The woman is doing
Speaker 5: very well. I'm just saying, you know, I'm wondering if.
Speaker 1: Three of the kids are basically private in the background
Speaker 1: there my mother out of my mind.
Speaker 5: I'm psychotic and I'm not How does how does a
Speaker 5: guy seriously, based on what we just learned, how does
Speaker 5: a guy like Snoop or Seth Rogan, who admittedly are
Speaker 5: habitual user, how are they so productive?
Speaker 1: How are they so I don't know?
Speaker 4: How does Willie Nelson do it for eight thousand years
Speaker 4: and he's one hundred years old. Some people some people
Speaker 4: just Richard's still alive. It doesn't Some people, I guess
Speaker 4: have good DNA. It's a different DNA. Wow, I had
Speaker 4: the I had the migraine and hive. Where they're biting
Speaker 4: or they're buying, there's a strain we don't know about.
Speaker 4: They just you know they're sharing among these it's like
Speaker 4: money where they share information.
Speaker 1: They may have a strength. Yeah, they may. Are you happy? Now?
Speaker 5: Do you feel good that you are using yourself off?
Speaker 5: Do you feel Vindegan? What I'm what I'm not happy about?
Speaker 4: If if what she said is accurate, which, by the way,
Speaker 4: why wouldn't we think it was accurate based science?
Speaker 5: Well, she's only talking about I mean, she may or
Speaker 5: may not have a prejudice.
Speaker 1: Is she personally like me?
Speaker 5: I'm a teetotal I do not touch this stuff, but
Speaker 5: I'm not against it.
Speaker 1: I don't I don't prosthlytize.
Speaker 4: This is what I did, and I saw the effect
Speaker 4: of it, and I thought, if that's the effect on me,
Speaker 4: and we're reading the study, Yeah, what's the effect.
Speaker 1: On the United States?
Speaker 4: Now you have John Banner, the X speaker of the
Speaker 4: house is working for a big organization that's pushing, you know,
Speaker 4: that's selling and lobbying and whatever. So it's we've come
Speaker 4: full circle. And is that surprising to you? John Baner
Speaker 4: was always cigarette.
Speaker 5: If John John Banner during his tenure, if he wasn't
Speaker 5: taking something, I don't know how the man survived.
Speaker 1: He was always danny. He played golf a lot too.
Speaker 4: Yeah, David Grubenheim, what do we got marijuana now?
Speaker 1: Is in the well?
Speaker 8: I would say it's an exclusive bluff, but not really.
Speaker 8: It's the club of things that Americans do that are
Speaker 8: bad for us and we just don't care.
Speaker 1: And not just Americans, but yes, that's true. It's global.
Speaker 8: Global Hamburgers, hamburger, How many hamburgers do.
Speaker 3: You eat a week?
Speaker 1: A week?
Speaker 5: A week, you'd have to go a month, maybe one
Speaker 5: a month.
Speaker 8: Average consumption of hamburgers by Americans is three a week.
Speaker 1: And that's bad. No, it's great.
Speaker 3: How much? How about how about soda?
Speaker 1: How about soda? Soda is a chronic problem in this country.
Speaker 1: I do know that.
Speaker 8: How many gallons does the average American consume each year?
Speaker 1: Well? Are we talking badlands?
Speaker 3: Uh? Average average?
Speaker 4: I don't know, but my wife my wife is My
Speaker 4: wife is addicted to die coke, which drives me crazy.
Speaker 4: I don't know how many gallons, Laura, do you produce it?
Speaker 4: Where do you drink soda?
Speaker 1: Soda? No, I don't drink soda. I drink water. Oh,
Speaker 1: there you go.
Speaker 5: I drink sparkling water, which I guess is soda. But
Speaker 5: it doesn't have the syrups and the sugars.
Speaker 6: But it has a lot of sodium.
Speaker 1: Has a lot of sodium.
Speaker 5: Yeah, And I just I would imagine the average the
Speaker 5: person who drinks soda is probably drinking minimum two to
Speaker 5: three glasses per day.
Speaker 4: Oh, I'm thinking more so, I'm thinking thirty five gallons
Speaker 4: a year. I'm just putting a number.
Speaker 1: I'll go ahead, forty gallons.
Speaker 3: Whoa about forty gallons a year.
Speaker 1: A year of soda? Yeah, gotta wash it on the hamburgers. Yeah.
Speaker 8: We actually this country, we're actually in going in the
Speaker 8: right direction. In two thousand, oh, we hit our high
Speaker 8: at fifty three gallons.
Speaker 1: So we're coming down, coming down. Yeah, good guy, just
Speaker 1: because it got expensive. That's yah. Well you know I
Speaker 1: was switching the pot.
Speaker 5: Yeah yeah, Well thanks, all right, So that's it.
Speaker 1: You're done with the that's it.
Speaker 4: Oh yeah, after we.
Speaker 1: Heard today, can I tell you something? I just want
Speaker 1: to see if I get another hive? All right, I'll
Speaker 1: give you all this stuff. I'm not smoking.
Speaker 4: My other allergies change. I got a ton of pots
Speaker 4: that I'm not using. Come on over, you got I
Speaker 4: still got the a bag of renning may want to
Speaker 4: get rid of that. No, I'm gonna use it for
Speaker 4: a barbeerge what are you waiting for to come over?
Speaker 4: A smoke fish with it? And thank you for being
Speaker 4: with us.
Speaker 1: Thank you everybody, Good luck out the Thank you producer, Laura,
Speaker 1: Thank you, Laura's in the window high. I wish she's
Speaker 1: saying he's got She's got the house. No Really.
Speaker 2: As another episode of Really No Really comes to a close,
Speaker 2: I know you're wondering, what are some other things about
Speaker 2: marijuana that most people don't know? Well, I'll give you
Speaker 2: the read on weed in a moment. The first let's
Speaker 2: thank our guest, doctor Bertha Madress. You can follow doctor
Speaker 2: maddress on x where she is at Madres Underscore Bertha
Speaker 2: our little shell hangs out on Instagram, TikTok, YouTube, and
Speaker 2: threads at Really No Really Podcast, And of course you
Speaker 2: can share your thoughts and feedback with us online.
Speaker 3: At reallynoreled dot com.
Speaker 2: Check out our full episodes on YouTube, hit that subscribe
Speaker 2: button and take that bell so you're updated when we
Speaker 2: release new videos and episodes, which we do each Tuesday.
Speaker 2: So listen and follow us on the iHeartRadio app, Apple podcasts,
Speaker 2: or wherever you get your podcasts. And now the answer
Speaker 2: to the question, what are some other things about weed
Speaker 2: that most people don't know? Well? Some colleges in the
Speaker 2: United States, including ones in Vermont, Oregon, and California, offer
Speaker 2: classes on how.
Speaker 3: To cultivate cannabis.
Speaker 2: So yes, you can get an actual degree in ganja.
Speaker 2: It's also possible that men and women absorb marijuana differently.
Speaker 2: A twenty fourteen study looked at how male and female
Speaker 2: rats responded to cannabis. The researchers found that the female
Speaker 2: rats were more sensitive to the pain relieving qualities of cannabis. However,
Speaker 2: the females were also more likely to become a nerd
Speaker 2: to the medicinal and psychotrophic effects of cannabis and possibly
Speaker 2: more susceptible to the negative side effects too. And lastly,
Speaker 2: at present, the cannabis market bost seventy one million users
Speaker 2: in the USA alone, almost fifty percent use it daily,
Speaker 2: and the industry has greeted four hundred and twenty eight
Speaker 2: thousand jobs.
Speaker 3: And yet I continue to labor here, underpaid and distinctly sober.
Speaker 2: BRILLIONA really is a production of iHeartRadio and Blase Entertainment.