WEBVTT - Selects: How The Pill Changed the World

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<v Speaker 1>Hey, everybody, here's Chuck this week on a Saturday with

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<v Speaker 1>a pretty relevant topic these days. Who knew that it

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<v Speaker 1>would be relevant again? And this is from June nineteenth,

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<v Speaker 1>twenty eighteen, How the Pill changed the world. I think

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<v Speaker 1>you know what pill we're talking about. Welcome to Stuff

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<v Speaker 1>you should know, a production of iHeartRadio.

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<v Speaker 2>Hey, and welcome to the podcast. I'm Josh Clark. There's

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<v Speaker 2>Charles W. Chuck Bryant, and there's the ghost of Jerry

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<v Speaker 2>Roland in the empty chair. Thanks again about this, Thanks

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<v Speaker 2>again to Ramsey.

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<v Speaker 1>Yeah, thanks Ramsey.

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<v Speaker 2>How do I feel about this? I feel great? The

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<v Speaker 2>pill is it has everything? This might be I just

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<v Speaker 2>love this episode already.

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<v Speaker 1>I do too, But I kind of like when we

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<v Speaker 1>did the female puberty episode. I just feel nervous. This

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<v Speaker 1>can be fine explaining female reproduction. I just I don't know.

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<v Speaker 2>Hey, man, we're just we're just explaining stuff.

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<v Speaker 1>I know, I know.

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<v Speaker 2>It's not like we're We're just we're just explaining stuff.

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<v Speaker 1>Just be cool, all right. So let's talk the pill.

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<v Speaker 2>Yeah, the opposite of having kids.

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<v Speaker 1>The pharmaceutical so famous that it's called the pill.

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<v Speaker 2>It is there. I read this New Yorker article about

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<v Speaker 2>a book on the birth of the pill, and now

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<v Speaker 2>I'm talking about it, so everything comes full circle. And

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<v Speaker 2>they were saying, like, there's like, you don't call anything

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<v Speaker 2>else the pill, Like viagra is not the pill. Antibiotics

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<v Speaker 2>isn't the pill. You don't call it the vacuum or

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<v Speaker 2>the meat grinder, right, Like, there's there's really nothing like that. Yeah,

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<v Speaker 2>nothing compares to it. And it's it's for good reason.

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<v Speaker 2>I mean, the pill is monumentally huge as far as

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<v Speaker 2>pharmaceuticals and medicine goes. I mean on the scale of

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<v Speaker 2>antibiotics easily.

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<v Speaker 1>Yeah, and it's it's the very first medication that was

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<v Speaker 1>designed for a non therapeutic purpose too. Yes, very interesting.

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<v Speaker 2>And so it's really difficult to over to overstate how

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<v Speaker 2>much of an impact the pill had when they released

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<v Speaker 2>it in I think nineteen sixties, when.

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<v Speaker 1>It came history first.

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<v Speaker 2>Yeah, let's right, let's do that. So let me set

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<v Speaker 2>the stage for you.

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<v Speaker 1>Please, Oh, you're bringing a catch out.

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<v Speaker 2>Back in back in the day. I'm going to do

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<v Speaker 2>my Charles Nelson Riley one man Show impression. Back in

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<v Speaker 2>the day, if you were a woman and you didn't

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<v Speaker 2>want to get pregnant, you had to coordinate with your

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<v Speaker 2>husband that he wear a condom, okay, sure, or boyfriend, Well,

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<v Speaker 2>that's like a whole other kettle of fish at this time. Yeah, supposedly,

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<v Speaker 2>and socially that went on all the time. There's plenty

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<v Speaker 2>of premarital sex, but socially speaking, only single men were

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<v Speaker 2>allowed to have premarital sex, which is like, who are

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<v Speaker 2>they having premarital sex with? Then, right, if they're the

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<v Speaker 2>only ones allowed to have premarital sex, considering, considering everyone

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<v Speaker 2>refused to officially recognize homosexuality even existed.

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<v Speaker 1>Yeah, I know where you get.

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<v Speaker 2>Okay, So there's a lot of double standards, a lot

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<v Speaker 2>of repression going on. But if you were if you

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<v Speaker 2>were a woman and you wanted to have sex, so

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<v Speaker 2>whether it was with the guy you were having sex

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<v Speaker 2>with or your husband, you you basically had to say

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<v Speaker 2>you got to wear a condom. And if you said no,

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<v Speaker 2>well you were sol one way or another, either you

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<v Speaker 2>weren't having sex or you're going to have sex without

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<v Speaker 2>a condom. And if that happened, there was a really

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<v Speaker 2>good chance that you were going to end up getting

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<v Speaker 2>pregnant just from having sex.

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<v Speaker 1>Yeah, the ball was entirely in the man's court, and

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<v Speaker 1>women did not have much say in the matter.

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<v Speaker 2>No, they didn't. There were a couple of things on

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<v Speaker 2>the market. So before the Industrial Revolution, there were like

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<v Speaker 2>folk remedies where you could use herbs and stuff like that.

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<v Speaker 2>Basically I think they're called herbal douches where you're just

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<v Speaker 2>like squeezing stuff in there and like hoping for the best.

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<v Speaker 1>Right.

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<v Speaker 2>And then by the depression there's something there's a whole

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<v Speaker 2>line of stuff called gynecological aids or feminine hygiene, I

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<v Speaker 2>think is what it's called. And some of them worked,

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<v Speaker 2>some of them kind of worked, some of them didn't work.

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<v Speaker 2>Some of them worked but would kill you or give

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<v Speaker 2>you chemical burns. There was a lot of problems, so

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<v Speaker 2>you didn't have a lot of options, right. And then

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<v Speaker 2>along with the fact that you actually didn't have that

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<v Speaker 2>many options socially, in nineteen fifty, thirty States and the

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<v Speaker 2>federal government said you can't have anything that can used

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<v Speaker 2>as a contraceptive and you can't even learn about it

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<v Speaker 2>from your doctor from school. Yeah, thirty states in the

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<v Speaker 2>federal government. This is nineteen fifty. Ten years later, the

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<v Speaker 2>pill comes out, and a couple of years after that,

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<v Speaker 2>five million American women are using it as a contraception,

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<v Speaker 2>and now it was in their hands. They had the

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<v Speaker 2>ability to decide for themselves whether sex late to pregnancy

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<v Speaker 2>or not.

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<v Speaker 1>Well, and sort of even then, because not all states

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<v Speaker 1>allowed it and not all doctors would give it out,

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<v Speaker 1>so it wasn't like, oh, the FDA said it's good

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<v Speaker 1>to go, so we can all get it. It was

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<v Speaker 1>still a fight. Yeah, for years and years of decades,

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<v Speaker 1>it really was. So I guess we should start with

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<v Speaker 1>a woman named Margaret Sanger. She is a very controversial figure,

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<v Speaker 1>founder of Planned parenthood. She's a nurse, and she wrote

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<v Speaker 1>in nineteen twelve about a magic pill that could prevent conception.

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<v Speaker 2>Yeah, just a theoretical hypothetical pill.

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<v Speaker 1>Right, And she's controversial for many reasons, not the leastes

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<v Speaker 1>which is her she was anti abortion. Kind of when

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<v Speaker 1>she was most famous, she was anti abortion and kind

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<v Speaker 1>of went all in on the pill and was like,

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<v Speaker 1>this is the way to do it, is to prevent

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<v Speaker 1>the pregnancy once you're pregnant.

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<v Speaker 2>Sorry, wow, gotcha.

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<v Speaker 1>And then you know there's the whole eugenics thing. We

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<v Speaker 1>should do a podcast on her, probably at some point

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<v Speaker 1>we should, because that's a rabbit hole right there.

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<v Speaker 2>Yeah, so, but she was the early champion of it.

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<v Speaker 2>She was she coined the term birth control, and I

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<v Speaker 2>think nineteen twelve as well.

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<v Speaker 1>Yeah, so in nineteen fourteen she started a newsletter called

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<v Speaker 1>The Woman Rebel. That's where birth control was first typed

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<v Speaker 1>out and distributed the words like you said. And then

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<v Speaker 1>in the nineteen twenties some breakthroughs happen in science where

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<v Speaker 1>they were able to identify a progesterone an estrogen and

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<v Speaker 1>realized kind of how it all worked.

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<v Speaker 2>Yeah, so at first they were looking at this stuff

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<v Speaker 2>as our fertility drugs, and then they noticed that it

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<v Speaker 2>actually could suppress fertility. And as they were I think

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<v Speaker 2>this is in the forties when they were really starting

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<v Speaker 2>in earnest or is it the twenties.

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<v Speaker 1>Well, I mean they were synthesizing it from animals, and

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<v Speaker 1>it was in early nineteen forty one.

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<v Speaker 2>I don't think they were even synthesizing. I think they

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<v Speaker 2>were extracting it. And then that's what you got in

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<v Speaker 2>your pill, was animal hormones.

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<v Speaker 1>Well, it says synthesize for animals, so maybe it was

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<v Speaker 1>a process, gotcha. But eventually in nineteen forty one, doctor Marker,

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<v Speaker 1>doctor Russell Marker, I just said it. Like James Bond.

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<v Speaker 1>For some reason, he discovered how to synthesize the synthetic

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<v Speaker 1>form of progesterone, which is called progestin, and that really

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<v Speaker 1>this is from wild yams, believe it or not. So

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<v Speaker 1>he did that and that changed everything. It did.

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<v Speaker 2>It made it cheaper, it made it easier to obtain.

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<v Speaker 1>You could research all of a sudden, right, yeah.

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<v Speaker 2>But you still couldn't really research, right because there were

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<v Speaker 2>laws on even doing research on birth control. So the

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<v Speaker 2>people who were doing this, it started out as Margaret Sanger.

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<v Speaker 2>She hooked up with a doctor named Pinkus and Gregory Pinkis,

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<v Speaker 2>who was a biologist, and he was interested in coming

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<v Speaker 2>up with birth control as well. Mary McCormick was there

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<v Speaker 2>for Saint Mary Catherine Catherine McCormick.

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<v Speaker 1>Of the McCormick I guesses.

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<v Speaker 2>Okay, So she lent a tremendous amount of her wealth

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<v Speaker 2>to this research. And then a guy named John Rock

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<v Speaker 2>who was a doctor who was also working on a

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<v Speaker 2>birth control pill. They all joined forces in the nineteen

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<v Speaker 2>fifties and started working on this really hard. But they

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<v Speaker 2>had a lot of roadblocks up against them, and they

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<v Speaker 2>cut a lot of corn and getting this thing out

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<v Speaker 2>into market.

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<v Speaker 1>Yeah, like going to Puerto Rico too, because they had

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<v Speaker 1>to for trials.

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<v Speaker 2>Right, and so this is not like Puerto Rico was like,

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<v Speaker 2>we don't want this, but you're forcing it on us. Anyway,

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<v Speaker 2>Puerto Rico had the exact opposite attitudes toward birth control

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<v Speaker 2>that the United States did at the time. Yeah, so

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<v Speaker 2>it was a good place to do it. They just

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<v Speaker 2>didn't inform anybody what was going on with this, that

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<v Speaker 2>this was a clinical trial. They just gave them some

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<v Speaker 2>pills and said, do you take these, it'll keep you

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<v Speaker 2>from getting pregnant.

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<v Speaker 1>Yeah, which they kind of came about by accident. Some

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<v Speaker 1>of the pills were contaminated with estrogen, and they used

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<v Speaker 1>that in scare quotes, I guess, just because what they

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<v Speaker 1>really mean is mixed by accident, and that reduced a

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<v Speaker 1>lot of the side effects, because that was one of

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<v Speaker 1>the big problems at first and continued to be for

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<v Speaker 1>a while, and eventually they landed on a drug company

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<v Speaker 1>called Cyril. There were two competing ones, and the other

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<v Speaker 1>one was Syntex and Cyril. So you pronounce it cerrel cerrel.

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<v Speaker 2>That's what I'm going with s E A R L E. Cyril,

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<v Speaker 2>I want to hear you say zerol.

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<v Speaker 1>They finally came up with they thought was the right formulation,

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<v Speaker 1>and in nineteen sixty two, Syntex came out with their

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<v Speaker 1>version and then pretty soon it was being marketed and

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<v Speaker 1>distributed after FDA approval in nineteen sixty one.

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<v Speaker 2>So yeah, So Cyril was the one who hooked up

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<v Speaker 2>with Sangler and Rock. Yeah, and they were the ones

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<v Speaker 2>who provided the pills for the clinical trial in Puerto Rico.

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<v Speaker 2>There was also a clinical trial in at a women's

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<v Speaker 2>mental asylum in Massachusetts, and the patients there didn't have

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<v Speaker 2>any informed consent. And when they released this formula, first

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<v Speaker 2>it was for guid ecological disorders things like ovari insists.

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<v Speaker 2>They knew it could be used to treat that, and

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<v Speaker 2>Cyril at the time was like it. They had no

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<v Speaker 2>expectations for this whatsoever. Yeah, and then within a year

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<v Speaker 2>there were half a million women in America who were

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<v Speaker 2>suddenly using this for gynecological problems, and Cyrel figured out, well, no,

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<v Speaker 2>they're actually using it for contraception. And so when they

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<v Speaker 2>went and saw it FDA approval and got it, that

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<v Speaker 2>was when the floodgates opened, like there was now a

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<v Speaker 2>pill on the market that could prevent contraception that was

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<v Speaker 2>the woman's to take, and all of a sudden there

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<v Speaker 2>was the first year there was one point two million

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<v Speaker 2>American women on the pill, and Cyril at first thought,

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<v Speaker 2>they're not going to want this. Women aren't going to

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<v Speaker 2>want to take a pill every day to keep from

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<v Speaker 2>getting pregnant. But they couldn't even finish the name pregnant

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<v Speaker 2>for like the pills were being grabbed from their hands. Yes,

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<v Speaker 2>you know, it was a huge deal.

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<v Speaker 1>It was. And then these pills were not very safe.

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<v Speaker 1>That's the upshot of this. The estrogen. There was way

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<v Speaker 1>too much estrogen. It was dangerous, it was causing cancer.

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<v Speaker 1>And in nineteen sixty nine very famous book came out

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<v Speaker 1>called The Doctor's Case Against the Pill, written by a

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<v Speaker 1>medical journalist named Barbara Seaman, and she got together with

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<v Speaker 1>a bunch of doctors and researchers and women and made

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<v Speaker 1>a case against the pill that it wasn't safe. There

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<v Speaker 1>was a senator named Gaylord Nelson who read the book,

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<v Speaker 1>took on birth control in Senate hearings, and in January

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<v Speaker 1>nineteen seventy in the Senate chamber. There was this testimony

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<v Speaker 1>about the pill going on, of course run only by men,

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<v Speaker 1>all the witnesses with only men testifying providing witness testimony.

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<v Speaker 1>But there was a woman there named Alice Wolfson and

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<v Speaker 1>her group, the DC Women's Liberation Group. They were sitting

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<v Speaker 1>there just getting more and more steamed.

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<v Speaker 2>Yeah, in these hearings at this time, these series were

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<v Speaker 2>kind of under the radar right until Alice Wolfson, Like

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<v Speaker 2>the bluide.

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<v Speaker 1>Span wasn't a thing yet, So they were just getting

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<v Speaker 1>more and more steamed watching all these men get up

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<v Speaker 1>there and talking about women's reproductive health.

0:13:00.360 --> 0:13:02.600
<v Speaker 2>And but not only that, they were also these people

0:13:02.600 --> 0:13:07.640
<v Speaker 2>were talking about how how dangerous the side effects were

0:13:07.640 --> 0:13:11.559
<v Speaker 2>with the pill, sure hypertension, blood clots, heart attacks, high

0:13:11.600 --> 0:13:15.640
<v Speaker 2>blood pressure, stroke, all of these things. And these the

0:13:15.679 --> 0:13:20.040
<v Speaker 2>women in the DC Women's lib Movement and including Alice Wilson,

0:13:20.080 --> 0:13:22.199
<v Speaker 2>were like, We've never heard this before in our lives.

0:13:22.240 --> 0:13:23.880
<v Speaker 2>How did our doctors not tell us this?

0:13:23.960 --> 0:13:26.320
<v Speaker 1>Well, that was the backstory, is that that none of

0:13:26.320 --> 0:13:29.320
<v Speaker 1>the doctors were sharing this information because they were getting

0:13:29.400 --> 0:13:31.040
<v Speaker 1>and it's you know, I think there's always been a

0:13:31.080 --> 0:13:35.320
<v Speaker 1>problem not across the board, but with doctors and pharmaceutical

0:13:35.360 --> 0:13:37.880
<v Speaker 1>companies right, pushing certain drugs over others.

0:13:38.400 --> 0:13:41.120
<v Speaker 2>But even but at the time it was way worse

0:13:41.520 --> 0:13:44.200
<v Speaker 2>it is now, like there was an disclosure. Yeah, there was.

0:13:44.320 --> 0:13:52.040
<v Speaker 2>There was a mentality among doctors, male doctors who who

0:13:52.080 --> 0:13:56.680
<v Speaker 2>believed that if you a woman was better off not

0:13:56.840 --> 0:14:00.439
<v Speaker 2>knowing you didn't want to get her all upset giving

0:14:00.440 --> 0:14:03.280
<v Speaker 2>her all the information didn't have side effects listed, right,

0:14:03.800 --> 0:14:07.079
<v Speaker 2>and if you did tell her, you ran the risks.

0:14:07.080 --> 0:14:10.280
<v Speaker 2>Since women were so suggestible, she might develop a stroke

0:14:10.679 --> 0:14:12.480
<v Speaker 2>just by thinking about it so much, so it was

0:14:12.520 --> 0:14:14.680
<v Speaker 2>better off just not telling her about it. Yet that

0:14:14.760 --> 0:14:18.800
<v Speaker 2>was the entire medical establishment at the time, and so

0:14:18.880 --> 0:14:22.040
<v Speaker 2>the pill went from this feminist icon in the sixties

0:14:22.400 --> 0:14:29.840
<v Speaker 2>to buy nineteen seventy, becoming an icon for white male patriarchy.

0:14:30.360 --> 0:14:39.160
<v Speaker 2>Medical patriarchy and how patients informed consent was a paramount

0:14:39.240 --> 0:14:42.160
<v Speaker 2>issue now and it just took on this other.

0:14:42.120 --> 0:14:46.080
<v Speaker 1>Role well, and informed consent was literally born. That day.

0:14:46.600 --> 0:14:50.200
<v Speaker 1>At that hearing, they finally heard an expert say estrogen

0:14:50.280 --> 0:14:53.960
<v Speaker 1>is to cancer, what fertilizer is deweed? And Alice Wolfson

0:14:54.040 --> 0:14:57.040
<v Speaker 1>stood up and started screaming. She was screaming, why are

0:14:57.080 --> 0:14:59.280
<v Speaker 1>you using women as guinea pigs. Why are you letting

0:14:59.320 --> 0:15:02.920
<v Speaker 1>drug companies murderers for profit and convenience? And it got

0:15:02.920 --> 0:15:05.960
<v Speaker 1>a lot of media attention, and really the aftermath of

0:15:05.960 --> 0:15:10.720
<v Speaker 1>those hearings is when this consumer health movement started and

0:15:10.760 --> 0:15:13.680
<v Speaker 1>they started in formed consent, they started having to list

0:15:14.440 --> 0:15:16.960
<v Speaker 1>side effects on bottles, and you know, it wasn't an

0:15:16.960 --> 0:15:21.000
<v Speaker 1>overnight thing, but it really changed the pharmaceutical industry forever.

0:15:21.320 --> 0:15:32.760
<v Speaker 2>Right, So the pill managed to accept this I guess iconography, right,

0:15:32.840 --> 0:15:36.680
<v Speaker 2>It became a symbol for this other thing, but still

0:15:36.680 --> 0:15:40.880
<v Speaker 2>managed to keep on keeping on. Like I think, so

0:15:40.960 --> 0:15:43.920
<v Speaker 2>eighty seven percent of women between eighteen and forty nine

0:15:44.320 --> 0:15:50.200
<v Speaker 2>in the US followed those hearings. Once Alice Wolfson and

0:15:50.400 --> 0:15:54.320
<v Speaker 2>the DC Women's Lib Movement made it a national thing,

0:15:55.360 --> 0:15:57.560
<v Speaker 2>and I think eighteen percent of them stopped taking the

0:15:57.600 --> 0:16:01.000
<v Speaker 2>pill as a result. But the pill didn't fall out

0:16:01.000 --> 0:16:04.120
<v Speaker 2>of popularity. It stood in as the as the icon

0:16:04.240 --> 0:16:09.000
<v Speaker 2>for informed consent, and then just after that was established,

0:16:09.040 --> 0:16:11.480
<v Speaker 2>it just went back to being the pill. I think

0:16:11.560 --> 0:16:14.120
<v Speaker 2>that's amazing. It is because it was this huge thing

0:16:14.160 --> 0:16:17.000
<v Speaker 2>in nineteen sixty for one thing, huge thing in nineteen

0:16:17.040 --> 0:16:20.080
<v Speaker 2>seventy for another thing, and now it's it's it's part

0:16:20.120 --> 0:16:21.720
<v Speaker 2>of the cultural zeitgeist forever.

0:16:22.120 --> 0:16:24.400
<v Speaker 1>Should we take a break, Yes, all right, we're going

0:16:24.440 --> 0:16:27.760
<v Speaker 1>to take a break. We're all excited about history, and

0:16:27.800 --> 0:16:52.560
<v Speaker 1>now we're going to get into science. Hey, let's talk

0:16:52.600 --> 0:16:56.600
<v Speaker 1>minstrel cycles. All right, let's man, because that's all that's

0:16:56.640 --> 0:17:02.040
<v Speaker 1>going on here is the pill manipulates the menstrual cycle

0:17:02.920 --> 0:17:06.520
<v Speaker 1>by tricking the body with synthetic hormones.

0:17:06.720 --> 0:17:10.120
<v Speaker 2>Yes, it tricks the body into thinking it's already released

0:17:10.119 --> 0:17:10.520
<v Speaker 2>an egg.

0:17:10.880 --> 0:17:12.520
<v Speaker 1>It's pretty brilliant, it is.

0:17:12.680 --> 0:17:14.879
<v Speaker 2>It is, But it's also kind of low fi if

0:17:14.920 --> 0:17:15.640
<v Speaker 2>you think about it.

0:17:15.640 --> 0:17:16.880
<v Speaker 1>It is very low it's neat.

0:17:17.359 --> 0:17:20.919
<v Speaker 2>So we should kind of give you an idea of

0:17:20.960 --> 0:17:26.119
<v Speaker 2>what the menstrual cycle is. Right, it's twenty eight days generally, Yes,

0:17:26.240 --> 0:17:29.920
<v Speaker 2>that's the rule of thumb. But yes, it's certainly different

0:17:29.960 --> 0:17:32.600
<v Speaker 2>for everyone, right, And I think it's also down to

0:17:32.720 --> 0:17:36.040
<v Speaker 2>like hours and stuff like that too. It's not just days.

0:17:36.119 --> 0:17:39.199
<v Speaker 2>It's a human construct, you know. But have you stopped

0:17:39.200 --> 0:17:42.120
<v Speaker 2>and ever thought about like how interesting it is that

0:17:42.119 --> 0:17:44.200
<v Speaker 2>the cycle of the moon is like twenty eight days

0:17:44.200 --> 0:17:48.159
<v Speaker 2>as well. Yeah, I think it's fascinating.

0:17:48.200 --> 0:17:50.840
<v Speaker 1>I know, I didn't say what fascinating. I never stopped it.

0:17:51.600 --> 0:17:53.680
<v Speaker 2>I just just in researching this, I was like, that's

0:17:53.720 --> 0:17:56.240
<v Speaker 2>the cycle of the moon as well. Oh that's interesting.

0:17:56.480 --> 0:18:00.400
<v Speaker 2>So anyway, over the say roughly twenty eight day period,

0:18:01.240 --> 0:18:04.720
<v Speaker 2>the whole thing starts with the petuitary gland getting a

0:18:04.760 --> 0:18:07.879
<v Speaker 2>little froggy and saying, hey, I'm going to release some

0:18:07.960 --> 0:18:12.320
<v Speaker 2>follicle stimulating hormone at that sh and that stuff floods

0:18:12.359 --> 0:18:15.160
<v Speaker 2>the body and it makes its way down to the

0:18:15.200 --> 0:18:18.840
<v Speaker 2>ovaries and it stimulates follicles, hence the name.

0:18:19.760 --> 0:18:22.600
<v Speaker 1>That's right. It makes these follicles and the ovaries grow,

0:18:24.000 --> 0:18:27.960
<v Speaker 1>and it just sets off a big series of events. Basically,

0:18:29.000 --> 0:18:32.200
<v Speaker 1>estrogen is triggers that peituitary gland again.

0:18:32.160 --> 0:18:35.440
<v Speaker 2>Yeah, because the follicles then in turn release estrogen.

0:18:35.119 --> 0:18:38.520
<v Speaker 1>Right, Yeah, And so the petutary gland is busy because

0:18:38.520 --> 0:18:42.800
<v Speaker 1>then it secretes what's called ganatotropin releasing hormone g little

0:18:42.880 --> 0:18:44.480
<v Speaker 1>N big R, big H.

0:18:44.880 --> 0:18:46.760
<v Speaker 2>One of the better abbreviations ever.

0:18:47.320 --> 0:18:48.880
<v Speaker 1>Yeah, because it looks sort of like guns n'.

0:18:48.840 --> 0:18:50.960
<v Speaker 2>Roses a little bit. Yeah, Oh, that.

0:18:51.840 --> 0:18:57.639
<v Speaker 1>GnRH, and that triggers a rise in lutinizing hormone l H.

0:18:58.680 --> 0:19:03.960
<v Speaker 2>Right, and so hormone goes back down to the ovarian

0:19:04.040 --> 0:19:09.959
<v Speaker 2>follicles and it it gets one of the follicles. So

0:19:10.080 --> 0:19:12.960
<v Speaker 2>if you have a bunch of ovarian follicles growing, one

0:19:12.960 --> 0:19:16.320
<v Speaker 2>of them is going to clearly it's the lead horse, right, Yeah,

0:19:16.359 --> 0:19:19.040
<v Speaker 2>it's going to develop into an egg. And as the

0:19:19.119 --> 0:19:22.320
<v Speaker 2>lutinizing hormone stimulates it to develop into an egg, the

0:19:22.400 --> 0:19:26.840
<v Speaker 2>egg pops off. The rest of the other follicles wither

0:19:26.880 --> 0:19:32.080
<v Speaker 2>and die, and then the egg travels down the fallopian

0:19:32.119 --> 0:19:35.960
<v Speaker 2>tube where it may or may not be fertilized.

0:19:36.080 --> 0:19:38.720
<v Speaker 1>Yeah, this is called the ovulation. And while this is

0:19:38.760 --> 0:19:43.440
<v Speaker 1>going on, in the background, the uterine lining the endometrium

0:19:43.520 --> 0:19:45.800
<v Speaker 1>is thickening up right, it's getting ready for business.

0:19:45.920 --> 0:19:48.919
<v Speaker 2>And the reason that is is because the estrogen and

0:19:49.000 --> 0:19:51.480
<v Speaker 2>the lutinizing hormone are causing that to happen.

0:19:51.560 --> 0:19:52.879
<v Speaker 1>Yeah, they're just rising and rising.

0:19:53.200 --> 0:20:00.680
<v Speaker 2>So the mucus in the vagina I'm saying, like even

0:20:00.720 --> 0:20:03.600
<v Speaker 2>more than usual right now. But the mucus in the

0:20:04.000 --> 0:20:09.639
<v Speaker 2>in the vagina also does it thicken? Yeah, So it

0:20:09.840 --> 0:20:13.800
<v Speaker 2>thickens is that after the egg has been fertilized, because

0:20:13.880 --> 0:20:17.359
<v Speaker 2>I think it would make it, it would become okay,

0:20:17.400 --> 0:20:20.840
<v Speaker 2>So it d thickens. The uterine lining thickens. I think

0:20:20.840 --> 0:20:23.639
<v Speaker 2>the vaginal mucus makes it makes it easier for sperm

0:20:23.680 --> 0:20:24.200
<v Speaker 2>to make its way.

0:20:24.280 --> 0:20:26.200
<v Speaker 1>Yeah, yeah, correct, Okay, sorry about that.

0:20:26.480 --> 0:20:30.640
<v Speaker 2>So that's so, if all that goes according to the

0:20:30.720 --> 0:20:33.440
<v Speaker 2>genetic plan, then those sperm are going to make their

0:20:33.480 --> 0:20:35.520
<v Speaker 2>way to an egg. The egg is going to become fertilized,

0:20:35.560 --> 0:20:37.600
<v Speaker 2>it's going to come down the Filippian tube attached to

0:20:37.640 --> 0:20:39.680
<v Speaker 2>the uterus, and it's going to start to grow into

0:20:39.800 --> 0:20:40.240
<v Speaker 2>a child.

0:20:40.720 --> 0:20:41.120
<v Speaker 1>Correct.

0:20:41.440 --> 0:20:46.640
<v Speaker 2>It might also not happen either. The woman involved might

0:20:46.720 --> 0:20:50.399
<v Speaker 2>not have sex, so there might be no sperm. The

0:20:50.480 --> 0:20:52.560
<v Speaker 2>sperm might not make it. There might be some sort

0:20:52.560 --> 0:20:54.320
<v Speaker 2>of barrier method being made.

0:20:54.200 --> 0:20:57.399
<v Speaker 1>Yeah, or being used. A dude may have bad sperm.

0:20:57.600 --> 0:21:01.439
<v Speaker 2>Sure. Regardless of how this happens. If the egg is

0:21:01.440 --> 0:21:06.000
<v Speaker 2>not fertilized, the egg eventually weather's up itself and dissolves

0:21:06.760 --> 0:21:10.639
<v Speaker 2>and that thickened endometrium is shed.

0:21:10.920 --> 0:21:13.119
<v Speaker 1>Basically, yeah, the uterine lining is shed.

0:21:13.240 --> 0:21:18.359
<v Speaker 2>Yes, So when that haves like kind of iron rich

0:21:18.760 --> 0:21:23.240
<v Speaker 2>blood tissue, right, Okay, that is menstruation, that's menstruation. So

0:21:23.320 --> 0:21:27.119
<v Speaker 2>when you think of but that's your period, Yeah, the

0:21:27.119 --> 0:21:30.600
<v Speaker 2>whole thing's menstruation. Well yeah, Okay, it's like a twenty

0:21:30.680 --> 0:21:33.600
<v Speaker 2>eight day cycle is menstruation because I always think of like, yeah,

0:21:33.640 --> 0:21:37.240
<v Speaker 2>the period's menstruation, right, No, that's actually the end of menstruation, right,

0:21:37.280 --> 0:21:40.520
<v Speaker 2>and then the whole cycle begins again. Right after that time,

0:21:40.680 --> 0:21:43.320
<v Speaker 2>the pituitary glands like, oh, all right, I'll release some

0:21:43.400 --> 0:21:47.520
<v Speaker 2>follicle stimulating hormone. The whole thing begins again. The pill

0:21:47.880 --> 0:21:53.800
<v Speaker 2>interrupts this by making the body think it's already released

0:21:53.840 --> 0:21:57.840
<v Speaker 2>an egg. Like when the egg comes off of the

0:21:57.880 --> 0:22:01.040
<v Speaker 2>follicle and makes its way down out of the Philippian tube.

0:22:01.080 --> 0:22:05.200
<v Speaker 2>The ovum makes his way down the Philippian tube, that's

0:22:05.240 --> 0:22:10.320
<v Speaker 2>when the estrogen and the progesterone levels are high. Okay,

0:22:10.840 --> 0:22:15.080
<v Speaker 2>So the pill introduces progesterone and estrogen levels and keeps

0:22:15.119 --> 0:22:19.760
<v Speaker 2>them high at all times, and therefore the body stops

0:22:19.760 --> 0:22:23.080
<v Speaker 2>releasing eggs because it thinks it's already released an egg.

0:22:23.119 --> 0:22:26.359
<v Speaker 1>Yeah, it just hijacks that whole process right. Synthetically, Yep.

0:22:27.560 --> 0:22:30.000
<v Speaker 1>The woman's body is amazing. It is when you think

0:22:30.080 --> 0:22:31.440
<v Speaker 1>about all that's going on.

0:22:31.560 --> 0:22:34.320
<v Speaker 2>Yeah, our body is not doing anything even remotely like that.

0:22:34.400 --> 0:22:35.920
<v Speaker 2>It's making like farts.

0:22:36.600 --> 0:22:39.119
<v Speaker 1>That's what I thought when I was researching this, I

0:22:39.160 --> 0:22:43.480
<v Speaker 1>was like, man, I've never felt less important. Yeah, and

0:22:43.520 --> 0:22:46.520
<v Speaker 1>like the insides of my body are just I got

0:22:46.520 --> 0:22:49.080
<v Speaker 1>some lungs doing some things. I got a heart, and

0:22:49.119 --> 0:22:51.080
<v Speaker 1>then like, I guess I'm still making sperm. I don't

0:22:51.080 --> 0:22:51.480
<v Speaker 1>even know.

0:22:51.720 --> 0:22:55.000
<v Speaker 2>I've got like a wheezy old donkey running the show

0:22:55.040 --> 0:22:58.159
<v Speaker 2>in there kind of dirty.

0:22:58.400 --> 0:23:03.080
<v Speaker 1>Oh goodness. So the endometrium still builds up in the

0:23:03.160 --> 0:23:06.840
<v Speaker 1>uterus and is released, but it's known as a withdrawal period.

0:23:06.880 --> 0:23:09.320
<v Speaker 1>So this is if you're on the pill. But that's

0:23:09.320 --> 0:23:11.800
<v Speaker 1>why your period while on the pill is going to

0:23:11.840 --> 0:23:13.520
<v Speaker 1>be generally lighter and shorter.

0:23:13.800 --> 0:23:17.800
<v Speaker 2>Yeah. And so technically this the pill mimics the structure

0:23:17.840 --> 0:23:21.560
<v Speaker 2>called the corpus luteum, yes, which is the thing that

0:23:21.640 --> 0:23:25.600
<v Speaker 2>releases progesterone and estrogen once an egg is released. So

0:23:25.640 --> 0:23:28.159
<v Speaker 2>the bodies like, oh, the corpus luteum's got it going on.

0:23:28.400 --> 0:23:30.680
<v Speaker 2>I don't need to release another egg. I also am

0:23:30.680 --> 0:23:33.119
<v Speaker 2>not going to have a period because during this time

0:23:33.200 --> 0:23:37.840
<v Speaker 2>after the pill, those hormone levels start to become like

0:23:37.880 --> 0:23:41.760
<v Speaker 2>a normal baseline in the woman's body. There's no endometrium

0:23:41.800 --> 0:23:44.960
<v Speaker 2>that builds up, and therefore there's no endometrium to shed.

0:23:45.280 --> 0:23:48.840
<v Speaker 1>Right, and I don't think we mentioned this yet. Progestin,

0:23:48.920 --> 0:23:52.560
<v Speaker 1>which is the synthetic progesterone, it's going to make that

0:23:53.160 --> 0:23:56.680
<v Speaker 1>vaginal mucus thicker, so you're right earlier. It is thinner

0:23:56.760 --> 0:24:00.119
<v Speaker 1>to make this sperm, make it excess the eggs easy.

0:24:00.680 --> 0:24:02.960
<v Speaker 1>It will thicken it up that mucus to make it

0:24:03.000 --> 0:24:07.520
<v Speaker 1>harder for the sperm. So it's and I think it's

0:24:07.560 --> 0:24:09.080
<v Speaker 1>just sort of like a one two punch to make

0:24:09.080 --> 0:24:12.480
<v Speaker 1>it even harder to get pregnant, although you can still

0:24:12.480 --> 0:24:16.400
<v Speaker 1>get pregnant, usually due to misuse of the pill, because

0:24:16.880 --> 0:24:18.439
<v Speaker 1>what you do is you take the pill at the

0:24:18.440 --> 0:24:24.480
<v Speaker 1>same time every day. It's all very synchronous and depends

0:24:24.520 --> 0:24:28.400
<v Speaker 1>on that timing, and if you don't time it out right,

0:24:29.200 --> 0:24:31.359
<v Speaker 1>your chances are getting pregnant are a little bit more.

0:24:31.640 --> 0:24:35.199
<v Speaker 1>But apparently if you're taking it exactly right at the

0:24:35.240 --> 0:24:38.720
<v Speaker 1>same time, then your failure rate is going to be

0:24:38.800 --> 0:24:41.640
<v Speaker 1>point three percent, So it's still technically possible.

0:24:41.840 --> 0:24:45.280
<v Speaker 2>Yes, it is point three percent possible.

0:24:45.000 --> 0:24:48.520
<v Speaker 1>Which offers up the question like why, Like when they

0:24:48.520 --> 0:24:51.640
<v Speaker 1>were developing the pill, they had it completely in their

0:24:51.680 --> 0:24:55.359
<v Speaker 1>control as to what they wanted to do with the

0:24:55.400 --> 0:24:59.359
<v Speaker 1>menstrual cycle, and they decided and I never knew this

0:25:00.080 --> 0:25:02.760
<v Speaker 1>very interesting. They decided to keep it on that twenty

0:25:02.800 --> 0:25:06.159
<v Speaker 1>eight day cycle because for a lot of reasons, they

0:25:06.200 --> 0:25:09.760
<v Speaker 1>thought the Rock thought the Catholic Church, because he was

0:25:09.920 --> 0:25:12.479
<v Speaker 1>a Catholic, they might be more willing to approve it

0:25:12.840 --> 0:25:14.000
<v Speaker 1>if it seemed more natural.

0:25:14.040 --> 0:25:16.120
<v Speaker 2>I guess right. He was way off there.

0:25:16.000 --> 0:25:18.600
<v Speaker 1>They thought, way off. He thought that women would be

0:25:18.640 --> 0:25:20.879
<v Speaker 1>more apt to take it if it didn't seem like

0:25:20.920 --> 0:25:23.400
<v Speaker 1>it was disrupting things too much. Yeah, like, it's still

0:25:23.400 --> 0:25:24.800
<v Speaker 1>in my regular cycle, right.

0:25:24.680 --> 0:25:28.159
<v Speaker 2>Because you do have that withdrawal period. It's not an

0:25:28.200 --> 0:25:30.800
<v Speaker 2>actual real period, but it does come at that at

0:25:30.800 --> 0:25:32.680
<v Speaker 2>the end of that the pill cycle.

0:25:33.000 --> 0:25:36.280
<v Speaker 1>Yeah, but they could have gotten rid of the period altogether.

0:25:35.960 --> 0:25:37.960
<v Speaker 2>Right, And a lot of people are like, well, go

0:25:38.000 --> 0:25:39.800
<v Speaker 2>do that. And there are pills on the market that

0:25:39.840 --> 0:25:43.040
<v Speaker 2>we'll talk about that do take away women's period. Yeah,

0:25:43.080 --> 0:25:46.320
<v Speaker 2>there's others that put them at different like spaces of

0:25:46.320 --> 0:25:48.600
<v Speaker 2>them out like like four times a year or something

0:25:48.680 --> 0:25:52.560
<v Speaker 2>like that. And people started looking into this and they're like, well,

0:25:52.560 --> 0:25:56.119
<v Speaker 2>wait a minute, like should shouldn't women be having periods?

0:25:56.880 --> 0:26:00.120
<v Speaker 2>And the answer is not necessarily right.

0:26:00.240 --> 0:26:02.240
<v Speaker 1>Yeah, I mean it's controversial, like you're not.

0:26:02.560 --> 0:26:05.920
<v Speaker 2>If you're not ovulating, you technically don't have to have

0:26:06.000 --> 0:26:10.200
<v Speaker 2>a period. And this Molly Edmunds wrote this really interesting pill,

0:26:10.400 --> 0:26:14.400
<v Speaker 2>that old Molly article. Yeah, like is a period necessary?

0:26:14.400 --> 0:26:15.440
<v Speaker 2>I think is what it's called.

0:26:15.920 --> 0:26:21.439
<v Speaker 1>And because women today have many more periods than our ancestors.

0:26:20.840 --> 0:26:22.960
<v Speaker 2>Right, something on the order of like four hundred and

0:26:23.040 --> 0:26:25.600
<v Speaker 2>fifty periods over the average woman's lifetime.

0:26:25.720 --> 0:26:28.320
<v Speaker 1>Yeah, about three times as many as our ancestors. Yeah.

0:26:28.359 --> 0:26:32.480
<v Speaker 2>So like back in like hunter gatherer, pre pre agricultural

0:26:33.040 --> 0:26:35.600
<v Speaker 2>women had about one hundred and sixty or something, right,

0:26:35.600 --> 0:26:38.159
<v Speaker 2>And that was because they had more kids, they breastfed longer,

0:26:38.440 --> 0:26:42.159
<v Speaker 2>they didn't live as long. Yeah, And so some people

0:26:42.200 --> 0:26:45.320
<v Speaker 2>make the point like, well, women are having more more

0:26:45.359 --> 0:26:50.119
<v Speaker 2>periods than ever before, and the body wasn't meant for this.

0:26:50.520 --> 0:26:53.119
<v Speaker 2>It's actually kind of rough on the body to have

0:26:53.160 --> 0:26:55.960
<v Speaker 2>a period. Like when the ovum pops off of the

0:26:55.960 --> 0:26:59.160
<v Speaker 2>fallopian tube, it leaves a scar on the ovary. Yeah,

0:26:59.200 --> 0:27:01.480
<v Speaker 2>and that scar has to be repaired, and to repair

0:27:01.840 --> 0:27:04.880
<v Speaker 2>the cells in the ovary have to divide, and as

0:27:04.880 --> 0:27:08.080
<v Speaker 2>long as they divide correctly, that damage will be repaired.

0:27:08.200 --> 0:27:12.120
<v Speaker 2>If they divide incorrectly. That damage can turn into ovarian cancer,

0:27:12.600 --> 0:27:16.800
<v Speaker 2>so that's a problem with it. There's also scarring with

0:27:18.600 --> 0:27:22.159
<v Speaker 2>the shedding of the endometrium, like actually having your period

0:27:22.240 --> 0:27:24.920
<v Speaker 2>itself can leave scarring the same deal, right.

0:27:25.240 --> 0:27:27.960
<v Speaker 1>Yeah, and I think does an iron deficiency come into play.

0:27:27.760 --> 0:27:30.800
<v Speaker 2>So that's actually a benefit of having a period. You

0:27:31.680 --> 0:27:35.280
<v Speaker 2>get rid of excess iron, which can lead to cardiovascular disease.

0:27:35.520 --> 0:27:37.199
<v Speaker 1>Well, and there are a couple of weeks during the

0:27:37.200 --> 0:27:42.359
<v Speaker 1>menstrual cycle where women have a lot a significant reduction

0:27:42.400 --> 0:27:45.640
<v Speaker 1>in blood pressure. So during the years you know, their

0:27:45.680 --> 0:27:49.600
<v Speaker 1>reproductive years, at least they are at I guess a

0:27:49.640 --> 0:27:52.600
<v Speaker 1>slightly lower risk of stroke and heart attacked.

0:27:52.600 --> 0:27:53.800
<v Speaker 2>I think like ten percent lower.

0:27:53.880 --> 0:27:55.840
<v Speaker 1>Yeah, well it's not bad, no, not at all.

0:27:56.000 --> 0:28:00.320
<v Speaker 2>So there's pros and there's cons to having a period.

0:28:00.680 --> 0:28:03.440
<v Speaker 2>The thing is, this is what Molly ultimately points out,

0:28:03.520 --> 0:28:06.800
<v Speaker 2>is we actually don't know if a period is necessary.

0:28:07.200 --> 0:28:12.200
<v Speaker 2>Like the pill is still relatively new, and I think

0:28:12.600 --> 0:28:16.159
<v Speaker 2>she quoted a doctor in their Doctor Susan roth Coo,

0:28:16.400 --> 0:28:23.480
<v Speaker 2>I think or Roco And she called the pill that

0:28:23.840 --> 0:28:30.359
<v Speaker 2>does away with periods entirely the greatest unregulated medical experiment

0:28:30.400 --> 0:28:34.800
<v Speaker 2>of all time. Yeah, and she makes a chilling point,

0:28:34.840 --> 0:28:37.040
<v Speaker 2>like we don't really know what the side effects are yet,

0:28:37.080 --> 0:28:39.560
<v Speaker 2>because all of this is too new, especially the pill

0:28:39.920 --> 0:28:42.000
<v Speaker 2>that does away with the period altogether.

0:28:42.720 --> 0:28:44.680
<v Speaker 1>Well, yeah, and they haven't done there are no long

0:28:44.800 --> 0:28:51.160
<v Speaker 1>term studies of menstrual suppression from oral contraceptives. At least,

0:28:51.800 --> 0:28:55.800
<v Speaker 1>they don't know about what that means for a woman.

0:28:55.840 --> 0:28:57.920
<v Speaker 1>They don't know because most of this testing is done

0:28:58.200 --> 0:28:59.800
<v Speaker 1>for women over eighteen, so they don't know what it

0:28:59.800 --> 0:29:03.920
<v Speaker 1>meant for women under eighteen right at all, because they're

0:29:03.920 --> 0:29:06.760
<v Speaker 1>just not involved in the research, even though they do

0:29:06.840 --> 0:29:09.600
<v Speaker 1>have research that shows about two thirds of women would

0:29:10.120 --> 0:29:12.360
<v Speaker 1>get rid of their period if they could do so safely.

0:29:13.040 --> 0:29:16.360
<v Speaker 1>Because I mean, we haven't even mentioned PMS or PPMD,

0:29:17.440 --> 0:29:21.520
<v Speaker 1>which is just isn't that like a really really severe

0:29:22.440 --> 0:29:24.040
<v Speaker 1>yeah form of PMS?

0:29:24.120 --> 0:29:28.240
<v Speaker 2>Yes, it's like much worse. Yeah yeah, But whereas like

0:29:29.440 --> 0:29:32.560
<v Speaker 2>PMS is is not a picnic to begin with, this

0:29:32.680 --> 0:29:34.720
<v Speaker 2>is this is like go to the hospital bad?

0:29:34.920 --> 0:29:37.880
<v Speaker 1>Right? Yeah, it can be at least yeah, so yeah,

0:29:37.920 --> 0:29:39.200
<v Speaker 1>that's really interesting to think about.

0:29:39.280 --> 0:29:44.280
<v Speaker 2>It also treats ovarian sists. There's other uses for birth

0:29:44.320 --> 0:29:47.320
<v Speaker 2>control pills too. Yeah, you want to take another break

0:29:47.320 --> 0:30:11.400
<v Speaker 2>and get back to it, I think. So Okay, okay, Chuck,

0:30:11.440 --> 0:30:13.560
<v Speaker 2>where are we? Oh we were talking.

0:30:13.360 --> 0:30:15.920
<v Speaker 1>About I'm over here hanging but on this cliff by

0:30:15.920 --> 0:30:17.000
<v Speaker 1>my fingernails.

0:30:17.400 --> 0:30:19.960
<v Speaker 2>I think you're doing great. Isn't they doing great? Everybody?

0:30:20.480 --> 0:30:21.280
<v Speaker 1>Yes? No?

0:30:21.640 --> 0:30:24.640
<v Speaker 2>So remember, so there are side effects both positive and

0:30:24.680 --> 0:30:28.560
<v Speaker 2>negative to taking the pill. There's some very common negative

0:30:28.560 --> 0:30:33.720
<v Speaker 2>side effects like nausea is a big one, weight gain

0:30:34.520 --> 0:30:38.160
<v Speaker 2>spotting which is called breakthrough menstruation, which is where you

0:30:39.000 --> 0:30:44.120
<v Speaker 2>have bleeding during the actual pill cycle, not the prescribed

0:30:45.600 --> 0:30:47.000
<v Speaker 2>period cycle of the pill.

0:30:47.760 --> 0:30:49.560
<v Speaker 1>Yeah. And I don't think we mentioned yet either that

0:30:49.960 --> 0:30:55.040
<v Speaker 1>in the pill prescription, in that monthly dose there are

0:30:55.120 --> 0:30:58.360
<v Speaker 1>seven not always, but the way they designed it was

0:30:58.360 --> 0:31:01.240
<v Speaker 1>there are seven placebo pills, right, that are in there

0:31:01.440 --> 0:31:03.400
<v Speaker 1>because you only take the pill for twenty one days

0:31:03.440 --> 0:31:05.840
<v Speaker 1>a month. But they put those extra seven pills in

0:31:05.880 --> 0:31:08.920
<v Speaker 1>there to keep women on that. I guess the thinking was,

0:31:08.960 --> 0:31:10.560
<v Speaker 1>if they're used to taking this pill every day, they

0:31:10.600 --> 0:31:10.840
<v Speaker 1>need to.

0:31:10.880 --> 0:31:13.240
<v Speaker 2>Keep doing it, right, it is a habit.

0:31:13.440 --> 0:31:15.760
<v Speaker 1>Yeah, if they don't for seven days, they might forget

0:31:15.760 --> 0:31:17.200
<v Speaker 1>on the eighth day, and that's bad news.

0:31:17.360 --> 0:31:20.400
<v Speaker 2>Yeah, So that's the most common way to do it,

0:31:20.440 --> 0:31:25.560
<v Speaker 2>and those that's a very easy type of pill to take,

0:31:25.720 --> 0:31:28.920
<v Speaker 2>right because all of them are the same level of hormone,

0:31:29.800 --> 0:31:34.160
<v Speaker 2>and the seven inert ones are usually a different color

0:31:34.200 --> 0:31:36.680
<v Speaker 2>and they come at the end of the month. It's

0:31:36.720 --> 0:31:40.480
<v Speaker 2>supposed to be easy. There's actually a recall right now

0:31:40.960 --> 0:31:45.160
<v Speaker 2>of Tatula. Did you see that? No Tatula has made

0:31:45.200 --> 0:31:48.840
<v Speaker 2>it by Alergan I think, And they recalled a lot

0:31:49.040 --> 0:31:52.200
<v Speaker 2>of their pills because they put the inert ones at

0:31:52.240 --> 0:31:55.120
<v Speaker 2>the beginning of the cycle accidentally, just bad packaging.

0:31:55.240 --> 0:31:56.120
<v Speaker 1>Yes, oh my gosh.

0:31:56.200 --> 0:31:57.960
<v Speaker 2>And if you look, you can clearly see that the

0:31:58.000 --> 0:32:01.080
<v Speaker 2>first like seven or different color, but where they're supposed

0:32:01.080 --> 0:32:03.320
<v Speaker 2>to be at the end, at the beginning, and that

0:32:03.440 --> 0:32:06.720
<v Speaker 2>is bad news if you're taking that pill. So if

0:32:06.760 --> 0:32:11.280
<v Speaker 2>you have Tatula, go check it right now and go

0:32:11.320 --> 0:32:11.920
<v Speaker 2>get some more.

0:32:12.520 --> 0:32:14.960
<v Speaker 1>Yeah, but I think I interrupted you. On the side

0:32:14.960 --> 0:32:19.760
<v Speaker 1>effects nausea, headaches, breast soreness, acne, depression, moodiness, weight gain,

0:32:19.880 --> 0:32:24.680
<v Speaker 1>decreased libido, and sometimes these can be like if if

0:32:24.680 --> 0:32:26.960
<v Speaker 1>you start out on the pill can be worse. A

0:32:26.960 --> 0:32:29.920
<v Speaker 1>few cycles in it might get better, and if it doesn't,

0:32:29.960 --> 0:32:31.960
<v Speaker 1>you can There are different pills out.

0:32:31.800 --> 0:32:35.080
<v Speaker 2>There, there are, there's so the the when those pills

0:32:35.080 --> 0:32:38.720
<v Speaker 2>originally came out that first formula I think it was called.

0:32:38.480 --> 0:32:42.200
<v Speaker 1>Like a novid that was the first one on the market, first.

0:32:42.040 --> 0:32:48.120
<v Speaker 2>One by Cyril Cerel, and they had ten milligrams of

0:32:49.320 --> 0:32:54.960
<v Speaker 2>progesterone or progestin and zero point one five milligrams of estrogen,

0:32:55.560 --> 0:32:59.480
<v Speaker 2>and that is like a nuclear bomb pill. Women had

0:32:59.560 --> 0:33:02.880
<v Speaker 2>the side effects from it, like all these side effects,

0:33:03.080 --> 0:33:06.280
<v Speaker 2>like each of them a mac truck, and they were

0:33:06.320 --> 0:33:09.680
<v Speaker 2>still willing to go through it to have control of

0:33:10.520 --> 0:33:14.760
<v Speaker 2>their body as far as pregnancy went. But they very

0:33:14.840 --> 0:33:17.880
<v Speaker 2>quickly figured out through further research, you can do the same.

0:33:18.040 --> 0:33:20.240
<v Speaker 2>And the reason they selected that is like they knew

0:33:20.280 --> 0:33:22.720
<v Speaker 2>that there was not going to be any ovulation with

0:33:22.760 --> 0:33:27.080
<v Speaker 2>ten milligrams of progesterone, and so they figured out that

0:33:27.160 --> 0:33:30.640
<v Speaker 2>you could formulate with a much lower amount of both

0:33:30.920 --> 0:33:35.320
<v Speaker 2>progestin and estrogen and still get the job done. And

0:33:35.360 --> 0:33:37.680
<v Speaker 2>they still do that today. I think the estrogen gets

0:33:37.680 --> 0:33:41.240
<v Speaker 2>down into the micrograms and you can get like two

0:33:41.280 --> 0:33:45.040
<v Speaker 2>point five milligrams of progesterone in some forms of the pill.

0:33:46.160 --> 0:33:49.040
<v Speaker 2>And then if so, if the pill is mistreating you,

0:33:49.360 --> 0:33:51.800
<v Speaker 2>what you're saying is there are options, right, Well.

0:33:51.680 --> 0:33:55.200
<v Speaker 1>Yeah, there are three main types of oral did I

0:33:55.280 --> 0:33:57.960
<v Speaker 1>say kypes? I think I did?

0:33:58.080 --> 0:33:59.160
<v Speaker 2>You also said zero?

0:34:00.480 --> 0:34:04.120
<v Speaker 1>There are three main types of the oral contraceptive pills

0:34:04.160 --> 0:34:09.880
<v Speaker 1>now combination pills, progestin only, and extended release, which are

0:34:09.920 --> 0:34:13.600
<v Speaker 1>the newest ones out there. The combination pill is the

0:34:13.600 --> 0:34:18.600
<v Speaker 1>most common pill that you will get. The Mini pill

0:34:18.719 --> 0:34:22.239
<v Speaker 1>is the progestin only and for some women that's better.

0:34:22.400 --> 0:34:25.800
<v Speaker 1>Like if you're breastfeeding and you can't have the estrogen

0:34:26.400 --> 0:34:28.480
<v Speaker 1>because it's going to affect your milk, you will probably

0:34:28.520 --> 0:34:32.040
<v Speaker 1>be on the mini pill and the mini piel peel.

0:34:32.400 --> 0:34:34.759
<v Speaker 1>It works in a couple of different ways. It makes

0:34:34.800 --> 0:34:38.640
<v Speaker 1>the endometrium too thin to accept that egg and it

0:34:38.680 --> 0:34:41.880
<v Speaker 1>won't allow it to attach. And again with the vaginal mucus,

0:34:41.920 --> 0:34:44.239
<v Speaker 1>it makes it too thick to allow the sperm to

0:34:44.320 --> 0:34:47.960
<v Speaker 1>reach the egg. But it is a little less effective,

0:34:48.520 --> 0:34:51.160
<v Speaker 1>but still effective, but a little less than the combination.

0:34:50.800 --> 0:34:54.560
<v Speaker 2>Pill because it's almost like a different they're different mechanisms.

0:34:54.680 --> 0:34:58.000
<v Speaker 1>Yeah, Like it's twenty eight active pills for the mini pill.

0:34:57.920 --> 0:35:00.200
<v Speaker 2>Right, But rather than tricking the body into thinking it's

0:35:00.200 --> 0:35:03.520
<v Speaker 2>released an egg, this is just making it hard to

0:35:03.560 --> 0:35:06.560
<v Speaker 2>get pregnant, yes, right, exactly. It's almost like a different

0:35:06.640 --> 0:35:09.279
<v Speaker 2>kind of pill, and then there's what's the.

0:35:09.239 --> 0:35:12.080
<v Speaker 1>Other kind, well, the combination pill the most common. There's

0:35:12.120 --> 0:35:13.760
<v Speaker 1>a few subtypes of that pill as well.

0:35:13.840 --> 0:35:16.600
<v Speaker 2>Right, So there's monophasic, which is what I was talking about,

0:35:16.640 --> 0:35:19.239
<v Speaker 2>where you've got twenty one pills and all of them

0:35:19.239 --> 0:35:24.520
<v Speaker 2>are the same dose of progestin and estrogen. And then

0:35:24.560 --> 0:35:28.120
<v Speaker 2>you've got the seven inert pills. And some women say

0:35:28.600 --> 0:35:30.920
<v Speaker 2>I'm not gonna have a period this month, and then

0:35:30.960 --> 0:35:33.360
<v Speaker 2>you just rather than taking those seven inert pills, you

0:35:33.440 --> 0:35:36.040
<v Speaker 2>just move on to the next month's twenty one pills.

0:35:36.320 --> 0:35:38.879
<v Speaker 1>Yes, and I believe with the monophasic, if you miss

0:35:38.920 --> 0:35:40.760
<v Speaker 1>a day, you can double up the next day.

0:35:40.600 --> 0:35:42.959
<v Speaker 2>Because it's the same amount of pills or the same

0:35:43.040 --> 0:35:46.200
<v Speaker 2>level of hormones. Right, So yeah, and that's far and

0:35:46.239 --> 0:35:49.399
<v Speaker 2>away the most common. There's bi phasic, which has two

0:35:49.440 --> 0:35:53.640
<v Speaker 2>different levels of hormones, and then triphasic has three different levels.

0:35:53.880 --> 0:35:57.880
<v Speaker 2>And the point of by phasic and triphasic is it

0:35:57.920 --> 0:36:01.839
<v Speaker 2>they're designed to give you the absolute minimum amount of

0:36:02.440 --> 0:36:08.200
<v Speaker 2>synthetic hormones that your body requires to keep from ovulating. Yes,

0:36:08.280 --> 0:36:11.680
<v Speaker 2>because the point is is the lower the amount of

0:36:11.719 --> 0:36:14.759
<v Speaker 2>hormones you have in there probably the better off you are,

0:36:15.040 --> 0:36:21.440
<v Speaker 2>whether it's cancer risk, moodiness, who knows, you're you're just

0:36:21.520 --> 0:36:24.720
<v Speaker 2>better off with the least amount that does the trick.

0:36:25.560 --> 0:36:28.319
<v Speaker 1>Yeah, And the kind of progestin in each of these

0:36:28.400 --> 0:36:31.320
<v Speaker 1>is going to vary. But the type of synthetic estrogen

0:36:31.600 --> 0:36:39.120
<v Speaker 1>is the same, right, It's called ethanyl estradiol eric estrata estradiol.

0:36:39.680 --> 0:36:41.440
<v Speaker 1>That's it ethanyl estradiole.

0:36:41.719 --> 0:36:46.680
<v Speaker 2>Yeah, but the progestin is the thing that differs sometimes right, correct.

0:36:47.200 --> 0:36:49.400
<v Speaker 2>And depending if like you're on a pill that uses

0:36:49.480 --> 0:36:51.719
<v Speaker 2>woing type of progestine, you can say, oh, I want

0:36:51.719 --> 0:36:53.879
<v Speaker 2>to try a different type of progestine. Then they'll say

0:36:53.920 --> 0:36:54.399
<v Speaker 2>here you go.

0:36:54.920 --> 0:36:57.000
<v Speaker 1>And then the extended cycle, which we talked about, this

0:36:57.040 --> 0:37:00.120
<v Speaker 1>is the newest, the newest one on the market, and

0:37:00.239 --> 0:37:03.560
<v Speaker 1>I believe isn't this the one that is can reduce

0:37:03.680 --> 0:37:06.839
<v Speaker 1>your period to like a few four times a year.

0:37:08.120 --> 0:37:11.520
<v Speaker 2>Yeah. So there's there's a couple of different there's seasonal

0:37:12.080 --> 0:37:15.239
<v Speaker 2>and season eke and they're called that because that four

0:37:15.320 --> 0:37:18.040
<v Speaker 2>time a year period you'll just be like, op, it's

0:37:18.160 --> 0:37:21.920
<v Speaker 2>fall up, it's summer, right, not in that order, but

0:37:22.000 --> 0:37:24.880
<v Speaker 2>you know what I'm saying. And then there's libral and

0:37:24.920 --> 0:37:27.000
<v Speaker 2>I'm sure there's other ones on the market too. We

0:37:27.080 --> 0:37:29.560
<v Speaker 2>don't mean to buzz market or anything like that. So

0:37:29.600 --> 0:37:32.520
<v Speaker 2>there's there's there's one that's like three hundred and sixty

0:37:32.560 --> 0:37:35.480
<v Speaker 2>five days, and then there's others that are eighty four days,

0:37:35.840 --> 0:37:38.439
<v Speaker 2>so that you have for either no periods at all

0:37:38.640 --> 0:37:42.040
<v Speaker 2>or four periods a year. Right, So there you go.

0:37:42.680 --> 0:37:44.480
<v Speaker 2>So there's a couple of other things I want to

0:37:44.520 --> 0:37:48.200
<v Speaker 2>hit on the pill is it's so much larger than

0:37:48.360 --> 0:37:52.640
<v Speaker 2>just birth control. Sure, I mean, just the fact that

0:37:52.640 --> 0:37:55.399
<v Speaker 2>it's birth control is an enormous thing. Like, like you said,

0:37:55.480 --> 0:37:57.040
<v Speaker 2>John Rock thought he was going to be able to

0:37:57.080 --> 0:38:00.799
<v Speaker 2>convince the Catholic Church that that this is okay thing.

0:38:01.719 --> 0:38:05.560
<v Speaker 2>That was not the case. In the late sixties, the

0:38:05.600 --> 0:38:10.120
<v Speaker 2>Black power movement really zeroed in on the pill, especially

0:38:10.160 --> 0:38:13.160
<v Speaker 2>the men of the Black Power movement, and said like

0:38:13.360 --> 0:38:17.360
<v Speaker 2>this is this is tantamount to black genocide. And they

0:38:17.480 --> 0:38:20.080
<v Speaker 2>definitely had like a case like there were plenty of

0:38:20.120 --> 0:38:25.959
<v Speaker 2>cases of black women who went into hospitals and gave

0:38:26.040 --> 0:38:30.160
<v Speaker 2>birth and then came out unknowingly sterilized, like the doctor

0:38:30.160 --> 0:38:32.600
<v Speaker 2>had just taken it upon himself to sterilize her after

0:38:32.600 --> 0:38:36.239
<v Speaker 2>delivering her baby. So they're like they had this, they

0:38:36.239 --> 0:38:39.600
<v Speaker 2>had this evidence to back this up, and it was

0:38:39.640 --> 0:38:44.319
<v Speaker 2>never shown. Like, yes, there was a conspiracy to to

0:38:44.960 --> 0:38:49.080
<v Speaker 2>wipe out black power in America through the pill, but

0:38:49.640 --> 0:38:51.920
<v Speaker 2>you like, there were plenty of black women at the

0:38:51.960 --> 0:38:54.560
<v Speaker 2>time who said, like, yeah, I can get birth control

0:38:54.640 --> 0:38:58.640
<v Speaker 2>pills easier than anything that you know down on the

0:38:58.920 --> 0:39:02.200
<v Speaker 2>corner clinic or something like that. And even even with

0:39:02.320 --> 0:39:06.680
<v Speaker 2>the early trials from John Rock and Gregory Pinkus, Like

0:39:06.760 --> 0:39:09.600
<v Speaker 2>one of the things that they zeroed in on Puerto

0:39:09.719 --> 0:39:13.640
<v Speaker 2>Rico for was because they thought that if they could

0:39:13.640 --> 0:39:19.880
<v Speaker 2>show that backwards Puerto Ricans of color could could learn

0:39:19.920 --> 0:39:23.120
<v Speaker 2>how to take the pill regularly, it would demonstrate that

0:39:23.200 --> 0:39:26.240
<v Speaker 2>women in the inner cities could, or women in developing

0:39:26.280 --> 0:39:30.920
<v Speaker 2>countries could. So there was definitely like a mentality toward

0:39:32.160 --> 0:39:36.439
<v Speaker 2>the white establishment being on board with the idea of

0:39:38.080 --> 0:39:42.840
<v Speaker 2>at least providing the tools for other for minorities to

0:39:44.080 --> 0:39:48.480
<v Speaker 2>control their rate of birth. That was just pure and simple.

0:39:48.560 --> 0:39:51.640
<v Speaker 2>That was a thought of it. Yeah, it was, and

0:39:51.680 --> 0:39:54.160
<v Speaker 2>it's had a tremendous amount of benefits too, But there

0:39:54.200 --> 0:39:56.239
<v Speaker 2>were some there was some darkness in the place that

0:39:56.280 --> 0:39:57.799
<v Speaker 2>it originally came from. As well.

0:39:58.440 --> 0:40:02.799
<v Speaker 1>Well, yeah, and of course anti abortion groups think that

0:40:02.840 --> 0:40:05.720
<v Speaker 1>the pill still to this day is an abortion causing

0:40:05.760 --> 0:40:06.719
<v Speaker 1>agent what they call in.

0:40:07.120 --> 0:40:08.960
<v Speaker 2>Do you know how to pronounce that a border fashion?

0:40:09.120 --> 0:40:11.879
<v Speaker 1>A border fashion? I think so, yeah, I think that's right.

0:40:14.600 --> 0:40:16.760
<v Speaker 1>Which you know, that's that's long been their argument.

0:40:16.880 --> 0:40:22.800
<v Speaker 2>Well, they their argument is that it makes the the

0:40:22.920 --> 0:40:28.280
<v Speaker 2>uterus hostile to a fertilized egg, like prolonged use would

0:40:28.280 --> 0:40:31.880
<v Speaker 2>prevent a fertilized egg that would otherwise attach from attaching.

0:40:32.280 --> 0:40:35.200
<v Speaker 2>And so that's for all intents and purposes, abortion in

0:40:35.239 --> 0:40:38.120
<v Speaker 2>their position, right, And yeah, that is I don't think

0:40:38.160 --> 0:40:40.400
<v Speaker 2>that one's settled by any stretch of the imagination.

0:40:41.880 --> 0:40:45.160
<v Speaker 1>So you got anything else, I got nothing else.

0:40:45.239 --> 0:40:47.439
<v Speaker 2>As I predicted belief, this is a good one.

0:40:47.560 --> 0:40:48.560
<v Speaker 1>Yeah. I think it was good.

0:40:48.680 --> 0:40:49.319
<v Speaker 2>I think it was great.

0:40:49.320 --> 0:40:50.080
<v Speaker 1>I hope we did all right.

0:40:50.239 --> 0:40:54.120
<v Speaker 2>Yeah, because we're not like patronizing. We've never been patronizing. No,

0:40:54.160 --> 0:40:56.640
<v Speaker 2>that might be like white dudes, but we're very much

0:40:56.680 --> 0:40:59.080
<v Speaker 2>aware that we're white dudes. And let me leave you

0:40:59.120 --> 0:41:01.720
<v Speaker 2>with this, white dude. If you're a white dude, whether

0:41:01.760 --> 0:41:04.799
<v Speaker 2>it's in America or the West or anywhere, your one

0:41:05.040 --> 0:41:10.200
<v Speaker 2>job is to have some perspective. That's your first and

0:41:10.239 --> 0:41:13.839
<v Speaker 2>foremost job. Take yourself out of your own shoes once

0:41:13.880 --> 0:41:17.200
<v Speaker 2>in a while, look around, put yourself in other people's shoes.

0:41:17.520 --> 0:41:20.520
<v Speaker 2>Your eyes will open widely in agog.

0:41:21.160 --> 0:41:22.240
<v Speaker 1>Some say walk a mile.

0:41:22.800 --> 0:41:25.600
<v Speaker 2>Sure, why not get a little weight off right.

0:41:25.560 --> 0:41:26.640
<v Speaker 1>At least go check the mail.

0:41:28.760 --> 0:41:30.680
<v Speaker 2>If you want to know more about the pill, just

0:41:30.719 --> 0:41:33.720
<v Speaker 2>type in the pill. It'll bring up some cool stuff

0:41:33.760 --> 0:41:36.279
<v Speaker 2>on how stuff Works dot com. And there's also a

0:41:36.320 --> 0:41:39.600
<v Speaker 2>really great American Experience site on PBS that had a.

0:41:39.600 --> 0:41:41.680
<v Speaker 1>Bat Man that was good. Yeah, so good.

0:41:42.560 --> 0:41:45.959
<v Speaker 2>And since I said American Experience and Chuck said, so good,

0:41:46.239 --> 0:41:47.520
<v Speaker 2>it's time for listener mail.

0:41:47.760 --> 0:41:52.680
<v Speaker 1>Oh no, it's not no listener mail today because we've

0:41:52.760 --> 0:41:56.520
<v Speaker 1>had some milestones here lately, and as we sit here

0:41:56.560 --> 0:41:59.759
<v Speaker 1>today in real time, we as a company are celebrating

0:42:00.000 --> 0:42:03.800
<v Speaker 1>the ten year anniversary of Stuff You Should Know again again,

0:42:04.600 --> 0:42:07.120
<v Speaker 1>but we're actually having the party today. And on the

0:42:07.160 --> 0:42:11.120
<v Speaker 1>same day, Apple announced at their.

0:42:12.880 --> 0:42:14.840
<v Speaker 2>WDCC, Yeah, their.

0:42:14.680 --> 0:42:18.560
<v Speaker 1>Developers conference, got up on stage and this one kind

0:42:18.560 --> 0:42:21.279
<v Speaker 1>of hit me, Like we had the thousand episodes that

0:42:21.400 --> 0:42:23.239
<v Speaker 1>was good. The ten years kind of hit me in

0:42:23.280 --> 0:42:25.560
<v Speaker 1>a big way. But they got up on stage today

0:42:25.560 --> 0:42:27.919
<v Speaker 1>and they said that Stuff You Should Know is now

0:42:28.040 --> 0:42:33.600
<v Speaker 1>the first podcast in history, first and only to reach

0:42:33.719 --> 0:42:39.240
<v Speaker 1>five hundred million downloads and streams on their platform, which

0:42:39.280 --> 0:42:43.680
<v Speaker 1>is I didn't know, No, it hit me too somehow.

0:42:43.719 --> 0:42:46.480
<v Speaker 1>Adam Carolla is in againness book of world's records. But

0:42:47.800 --> 0:42:50.920
<v Speaker 1>here we are as the only one. And that's because

0:42:50.920 --> 0:42:54.120
<v Speaker 1>of you all out there. Yes you said a gazillion times,

0:42:54.200 --> 0:42:57.319
<v Speaker 1>but without you, there is no us. We would have

0:42:57.320 --> 0:42:59.759
<v Speaker 1>been long gone if not for your support, So we

0:42:59.800 --> 0:43:01.080
<v Speaker 1>canntinue to give thanks.

0:43:01.280 --> 0:43:05.359
<v Speaker 2>Thank you again. Yeah, we and will continue to give thanks.

0:43:05.200 --> 0:43:07.360
<v Speaker 1>And we will continue to podcast.

0:43:07.760 --> 0:43:09.359
<v Speaker 2>Yes we will chuck, Yes we will.

0:43:09.440 --> 0:43:10.280
<v Speaker 1>And that's all I got.

0:43:10.440 --> 0:43:13.279
<v Speaker 2>If you want to get in touch with us, you

0:43:13.320 --> 0:43:15.640
<v Speaker 2>can send us all an email the Stuff podcast at

0:43:15.640 --> 0:43:18.719
<v Speaker 2>houstuffworks dot com and as always, joined us at our

0:43:18.960 --> 0:43:26.080
<v Speaker 2>extraordinarily grateful home on the web, Stuff youshould Know dot com.

0:43:26.200 --> 0:43:29.080
<v Speaker 1>Stuff you Should Know is a production of iHeartRadio. For

0:43:29.160 --> 0:43:33.359
<v Speaker 1>more podcasts my Heart Radio, visit the iHeartRadio app, Apple Podcasts,

0:43:33.440 --> 0:43:35.320
<v Speaker 1>or wherever you listen to your favorite shows.