WEBVTT - Disease Takes Flight on Leathery Wings

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<v Speaker 1>Welcome to Stuff to Blow your Mind from how Stuff

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<v Speaker 1>Works dot com. Hey, welcome to Stuff to Blow your Mind.

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<v Speaker 1>My name is Robert Lamp and I'm Christian Segre. Hey, Robert,

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<v Speaker 1>I got a superhero question for you, Batman. Why doesn't

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<v Speaker 1>he have any disease related abilities or or like an

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<v Speaker 1>improved immune system? So, so, you know, Batman has been

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<v Speaker 1>around for like over seventy years, we largely know bats

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<v Speaker 1>as being disease carriers, right, and yet he doesn't seem to,

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<v Speaker 1>I mean outside of like I guess like he has

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<v Speaker 1>a little pellets on his pouch that he occasionally uses

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<v Speaker 1>to throw gas at people, but I don't think it's

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<v Speaker 1>like he's throwing a bowl at them. Yeah, it's interesting

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<v Speaker 1>when you start taking apart Batman, right, because in what

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<v Speaker 1>ways is Batman actually like a bat at all? Or

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<v Speaker 1>or perhaps more telling, in what ways, was was he

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<v Speaker 1>even initially like a bat? Because I know a number

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<v Speaker 1>of talented writers and artists have had a had a

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<v Speaker 1>chance over the years to build on the Batman mythos

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<v Speaker 1>and occasionally incorporate bits of bat science. But was maybe

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<v Speaker 1>you can answer this, was he essentially just a dude

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<v Speaker 1>in a mask? Because this this recently, I watched a

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<v Speaker 1>large portion of the the really bad nine nine Batman

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<v Speaker 1>and Robin series is like a serial black and white

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<v Speaker 1>forty nine. So this is pre uh the TV show.

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<v Speaker 1>I don't I don't think I've seen this riff tracks

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<v Speaker 1>has been installments of it, and it's it's really bad.

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<v Speaker 1>It's from several different vantage points. It has, uh, there's

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<v Speaker 1>some anti Japanese sentiment that's in there. It has this

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<v Speaker 1>just terrible villain that's just called the Wizard, that's like

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<v Speaker 1>a just an old dude in a black robe, and

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<v Speaker 1>and it's just it. It's the the campus versions of

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<v Speaker 1>Batman and Robin as well, you know what you would like.

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<v Speaker 1>And we have never talked about this off air before.

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<v Speaker 1>It is just popping in my head. Now, have you

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<v Speaker 1>ever heard of bat manga? It's so um Japan's version

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<v Speaker 1>of Batman done as manga. It's there's some really old

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<v Speaker 1>stuff and there's a whole book that Chip Kid put

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<v Speaker 1>together that's a collection of the bat manga comics, so

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<v Speaker 1>you get an idea of what Japan's iteration of Batman

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<v Speaker 1>and Robin were like. But then also just like photographs

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<v Speaker 1>of all of the collectibles, the Japanese collectibles related to Batman. Anyways,

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<v Speaker 1>It's fascinating because when you mentioned this Batman villain, the Wizard,

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<v Speaker 1>Like when you think of your like top rogues for Batman,

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<v Speaker 1>the Wizard isn't really high up there. Uh, and the

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<v Speaker 1>batmana stuff is very similar. He's got all these like

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<v Speaker 1>totally bizarre characters that he interacts with. From a Western perspective,

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<v Speaker 1>the thing that's interesting to me about the Wizard is

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<v Speaker 1>that it seems like somebody would have brought the Wizard

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<v Speaker 1>back just for the sake of doing it. Like it

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<v Speaker 1>seems like the kind of thing like a Grant Morrison

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<v Speaker 1>would say, Hey, nobody's brought this character back. What's some

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<v Speaker 1>sort of crazy counterculture span I can put on it? Yeah,

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<v Speaker 1>you know, you're right. Actually, so it's funny you mentioned

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<v Speaker 1>that Grant Morrison did bring back one of the weird

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<v Speaker 1>villains from The Batman. So yeah, I think his name

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<v Speaker 1>was like Mr. Deathman or something like that. It's like

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<v Speaker 1>a guy in a skeleton costume. Um. Anyways, Yeah, he

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<v Speaker 1>doesn't really have bat abilities right, Like, so, uh, he

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<v Speaker 1>doesn't really fly. He glides for the most part, does

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<v Speaker 1>not have powered flight, which is the big deal with that. Yeah,

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<v Speaker 1>and we're gonna talk a lot about that today. I

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<v Speaker 1>guess he has the bat plane that could kind of

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<v Speaker 1>count sometimes, but yeah, exactly. Um, he does use like echolocation.

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<v Speaker 1>I think that's become like more of a thing since

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<v Speaker 1>those Christopher Nolan movies. Yeah, I feel like that's definitely

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<v Speaker 1>a case where Invented Riders came in and said, hey,

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<v Speaker 1>we should make him behave a little like a bat

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<v Speaker 1>solce thrown. Yeah, those Arkham video games like, you can

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<v Speaker 1>use the echolocation stuff pretty frequently. They call it detective mode,

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<v Speaker 1>and you can basically like everything around you, kind of

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<v Speaker 1>like a radar fashion. I wonder has anyone ever decided

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<v Speaker 1>to have Bruce Wayne and Batman is essentially a fruit

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<v Speaker 1>bat where when he's not fighting crimes, just setting around

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<v Speaker 1>ian mangoes all day. Right, Yeah, I don't you know.

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<v Speaker 1>If anybody would do it would be Morrison and likewise

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<v Speaker 1>you have down here. If he was a fruit bat,

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<v Speaker 1>can he lack tape? That would be great too. That

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<v Speaker 1>would put a new maternal spin on it because of

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<v Speaker 1>just to throw out the quick snapshot of the science, uh,

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<v Speaker 1>certain varieties of male fruit bats lactate in order to

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<v Speaker 1>help we're the young, like most males. Uh well, let

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<v Speaker 1>me say that male humans can lactate is well under

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<v Speaker 1>the reser scenarios. But the male fruit bat in this

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<v Speaker 1>case is the only example of a mammal that regularly

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<v Speaker 1>lactates to help real young. Yeah. The only thing I

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<v Speaker 1>can think of that's even moderately close to that is

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<v Speaker 1>again Morrison introduced a bat cow. You know, like Batman

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<v Speaker 1>and Superman have like pets. He has like a dog

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<v Speaker 1>and a cat, and like Superman has a horse and

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<v Speaker 1>stuff like that. Is this really a thing? Yeah, totally.

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<v Speaker 1>Superman has a horse. Yeah, comment the super horse. I

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<v Speaker 1>think Supergirl rides, ok, yeah, and it flies. But but

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<v Speaker 1>Batman had a cow. Uh in the Grant Morris in

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<v Speaker 1>line because I think, like Robin like, they infiltrated some

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<v Speaker 1>criminal headquarters where they're like abusing cows, and Robin like

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<v Speaker 1>saved one of the cows and brought it back to

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<v Speaker 1>Wayne Manner and it had like the markings on its face,

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<v Speaker 1>like the way that its coloration on his face was

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<v Speaker 1>looked like a bad symbol. Alright, like that, but all right,

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<v Speaker 1>let's bring it back to sort of reality for a

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<v Speaker 1>second year. He doesn't really have any disease related abilities.

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<v Speaker 1>And I'd say, like, if you walk up to most

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<v Speaker 1>people in the street and you say, like, hey, bats

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<v Speaker 1>what are the first three things you know about them? Right,

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<v Speaker 1>they'd be like, they fly, they have echolocation, and they

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<v Speaker 1>their carriers of disease. Right. Um, So yeah, I don't know.

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<v Speaker 1>Maybe when you and I get our hands on the

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<v Speaker 1>Batman franchise in ten or twenty years, will finally be

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<v Speaker 1>able to write that like Batman as the Black Plague. Well,

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<v Speaker 1>I guess it comes down to the idea that certainly

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<v Speaker 1>you have comic book characters that are embodiments of disease.

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<v Speaker 1>But there, you know, I think almost all villains. I

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<v Speaker 1>can't think of a hero off the top of my head.

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<v Speaker 1>I'm sure there's somebody. There's this really silly one. Oh God,

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<v Speaker 1>I can't remember what her name is, Infectious Lass. I

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<v Speaker 1>think she's one of the legions of the Legion of Superheroes.

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<v Speaker 1>That's the only one I can think of. But why

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<v Speaker 1>are we talking about this? Why are we talking about bats? Well,

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<v Speaker 1>if you're a long time listener stuftable in your mind,

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<v Speaker 1>you know probably for the last year I've been casually

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<v Speaker 1>saying we should do an episode on bats, we should

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<v Speaker 1>do an episode on bats, And then we did the

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<v Speaker 1>Patient zero episode, and we were talking about bats there

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<v Speaker 1>because of how they spread disease, zoonotic disease. We specifically

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<v Speaker 1>talked about the case of Dr lu Jian Lun, who

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<v Speaker 1>was a sixty four year old doctor in China's Guangda

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<v Speaker 1>Province UH, and he apparently transferred UH STARS I believe

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<v Speaker 1>it was to sixteen other guests staying on the same

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<v Speaker 1>floor of like a hotel UH and this seemed to

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<v Speaker 1>be a case of super spreading. We talked about this

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<v Speaker 1>a lot in the Patient zero episode. We get into

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<v Speaker 1>the idea of how STARS was sort of a bat

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<v Speaker 1>disease right that it was a zootic infectious disease. It

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<v Speaker 1>jumped from one species to another UH. This step involved

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<v Speaker 1>the virus being able to transmit then from human to

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<v Speaker 1>human without an animal reservoir like a bat. So it

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<v Speaker 1>was believed that STARS originated in bats and then spread

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<v Speaker 1>to other animals like civic cats, and then the civic

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<v Speaker 1>cats infected humans. Another thing that we talked about related

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<v Speaker 1>to bats was that they've got all kinds of diseases

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<v Speaker 1>that they're related to the Bola hepatitis c Stars and

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<v Speaker 1>also perhaps mers UH. In the case of Stars, it

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<v Speaker 1>was thought that it spread to humans in by bats

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<v Speaker 1>infecting horses in Brisbane, Austra Alia. Then two people caught

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<v Speaker 1>that virus from the horses, possibly from scratches, are being

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<v Speaker 1>exposed to infected blood. Both died horrible deaths UH and

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<v Speaker 1>other diseases. So they think maybe pigs have become infected

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<v Speaker 1>by eating saliva colored fruit that bats have just dropped,

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<v Speaker 1>and then the pigs infect humans. So it doesn't seem

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<v Speaker 1>like a lot of these zoonotic infection cases that bats

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<v Speaker 1>are biting humans and humans are getting the disease. It's

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<v Speaker 1>like various ways bats are infecting other animals and then

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<v Speaker 1>those other animals are infecting humans. They're just a major

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<v Speaker 1>conduit in the chain. Yeah. So um. We received a

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<v Speaker 1>little bit of listening mail about this, asking for clarification,

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<v Speaker 1>people who were concerned primarily about like the conservation of bats,

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<v Speaker 1>and the idea that maybe we didn't give the full

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<v Speaker 1>story and that that would subsequently lead to more fearmongering

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<v Speaker 1>of bats, right, and far be it from us. That

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<v Speaker 1>is the last thing I want to do. In fact,

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<v Speaker 1>I have to just as a subjective thing before we

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<v Speaker 1>really get into bat I've spent some time in Austin,

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<v Speaker 1>Texas recently, and if anybody who's gone there and that

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<v Speaker 1>they know about the Batbridge, yeah, and man alive. I

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<v Speaker 1>love the Bat Bridge. It's so much fun. If you've

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<v Speaker 1>never been, I forget I thinks the Congress Street bridge

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<v Speaker 1>in Austin. But you go there certain times a year,

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<v Speaker 1>certain times a night, millions of bats live under this

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<v Speaker 1>bridge and they all fly out from under the neath

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<v Speaker 1>this bridge all at the same time. You get to

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<v Speaker 1>see them for about like thirty minutes, just the swarm

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<v Speaker 1>of them up in the air, flying around and then

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<v Speaker 1>going off to various parts of Austin to you know,

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<v Speaker 1>collect their food for the night, basically before they go

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<v Speaker 1>back to sleep under the bridge during the day. Again. Uh,

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<v Speaker 1>I like bats, Like if a bat was caught in

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<v Speaker 1>my home, like, my reaction wouldn't be killing, It would

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<v Speaker 1>be like, oh, let's capture that guy and then let

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<v Speaker 1>him back outside. Yeah. I U. I have to say that.

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<v Speaker 1>On vacations, especially vacations to the Caribbean, which I've got

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<v Speaker 1>to go in on two of those in the last

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<v Speaker 1>couple of years, I've always both trips. I just really

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<v Speaker 1>enjoyed watching the bats when the sun began to go down. Um,

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<v Speaker 1>you know, they're just fascinating creatures. And uh, and when

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<v Speaker 1>I have captured them in the house before, not not

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<v Speaker 1>my house, but like a vacation house they staying. And

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<v Speaker 1>one time over a weekend they we found it. It

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<v Speaker 1>had somehow gotten trapped in the house and it was

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<v Speaker 1>trying to like get water out of the sink, and

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<v Speaker 1>I thought it was a tea bag at first. I'm

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<v Speaker 1>glad retrospect that I did not like gravitated or put

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<v Speaker 1>in my tea and have some horrible bat tea concoction.

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<v Speaker 1>But my son and I like made up, you know,

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<v Speaker 1>an activity out of freeing the bat from the house

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<v Speaker 1>and helping it get away. So yeah, bats are fascinating creatures.

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<v Speaker 1>Were certainly not trying to spread any fear about it.

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<v Speaker 1>In fact, this episode is about spreading some truth on

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<v Speaker 1>the matter. Yeah. In fact, we have actually gotten to

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<v Speaker 1>the point where between yes, bats carrying a lot of disease,

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<v Speaker 1>but they have these fascinating immune systems that we're starting

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<v Speaker 1>to look at the science of their anatomy how it

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<v Speaker 1>deals with these viruses and then how we might apply

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<v Speaker 1>that to human beings. Bats maybe the key to us

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<v Speaker 1>living longer lives and fighting off diseases that currently are

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<v Speaker 1>pretty dangerous to human beings. One day we may all

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<v Speaker 1>be batman and bad girls. Yeah exactly. And you know,

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<v Speaker 1>unlike Bruce Wayne, we will maybe carry viruses, but our

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<v Speaker 1>immune systems will be so fast that will just be

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<v Speaker 1>constantly compromising them. All right, Well, should we get down

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<v Speaker 1>to brass tacks the Yeah, let's just let's do a

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<v Speaker 1>little overview about bats. I think we should say. First

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<v Speaker 1>of all, like stuff to blow your mind. Before I

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<v Speaker 1>was on it did a bunch of bad episodes. You

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<v Speaker 1>and Julie have talked about them extensively. Um, so let's

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<v Speaker 1>just do a refresher. Okay. So, all told, they're about

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<v Speaker 1>five different species of bats in the world, and they

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<v Speaker 1>make up about a quarter of all mammal species. Uh.

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<v Speaker 1>There are forty five different species of bats that live

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<v Speaker 1>in the United States and Canada. Most bats species live

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<v Speaker 1>in the tropical regions of the world. Now, evidence for

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<v Speaker 1>bat like flying mammals appears as far back as that

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<v Speaker 1>you're seeing e box, some fifty million years ago. However,

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<v Speaker 1>the fossil record tracing bat evolution is incomplete, so based

0:12:21.120 --> 0:12:25.480
<v Speaker 1>on similarities of bones and teeth, most authorities agree that

0:12:25.760 --> 0:12:31.400
<v Speaker 1>bats ancestors were probably insect eating animals, possibly living in

0:12:31.400 --> 0:12:34.280
<v Speaker 1>the trees, and they likely the same group that gave

0:12:34.400 --> 0:12:38.160
<v Speaker 1>rise to shrews and moles. So bats are are not

0:12:38.400 --> 0:12:41.480
<v Speaker 1>rodents and they're not even uh closely related to that

0:12:41.520 --> 0:12:44.240
<v Speaker 1>group of mammals. Yeah, that's really important for what we're

0:12:44.240 --> 0:12:47.400
<v Speaker 1>going to discuss today too, because they're often compared to

0:12:47.559 --> 0:12:50.920
<v Speaker 1>rodents in terms of how the two different species act

0:12:50.960 --> 0:12:54.240
<v Speaker 1>as disease carriers. You think it's like a flying mouse. Yeah,

0:12:54.520 --> 0:12:58.720
<v Speaker 1>so most bats in UH in North America eat insects.

0:12:58.760 --> 0:13:00.880
<v Speaker 1>As a matter of fact, one at eats about two

0:13:00.920 --> 0:13:05.760
<v Speaker 1>thousand to six thousand insects each night. Wow. And just

0:13:05.800 --> 0:13:08.880
<v Speaker 1>a few other crazy cool facts about them. When it

0:13:08.880 --> 0:13:11.560
<v Speaker 1>comes to flying, it's it's easy to think, oh, it's

0:13:11.559 --> 0:13:13.920
<v Speaker 1>just it's a it's about with it's a mouse with wings.

0:13:13.920 --> 0:13:16.520
<v Speaker 1>It's like a cross between a mouse and a bird. Well,

0:13:17.320 --> 0:13:21.800
<v Speaker 1>it's more complicated and more amazing than that. So throughout

0:13:21.880 --> 0:13:27.360
<v Speaker 1>human history, we've only had a few evolutionarily distinct modes

0:13:27.559 --> 0:13:30.640
<v Speaker 1>of flight, and there are only three distinct modes of

0:13:30.720 --> 0:13:36.280
<v Speaker 1>vertebrate flight flight. There there's the terasarian flight that was

0:13:36.440 --> 0:13:42.679
<v Speaker 1>you know employed by the by by pterodactyls, pterodactyls, um taranodons, etcetera.

0:13:42.800 --> 0:13:45.280
<v Speaker 1>And then you have avian flight, and then you have

0:13:46.080 --> 0:13:49.400
<v Speaker 1>chiropter in flight, which is bats. So these are distinct

0:13:49.440 --> 0:13:52.679
<v Speaker 1>modes of flight that were that were that evolved separately.

0:13:53.120 --> 0:13:55.559
<v Speaker 1>And then on top of that there there's insect flight

0:13:55.640 --> 0:14:00.560
<v Speaker 1>as well. So four models all told. Now you once

0:14:00.640 --> 0:14:03.520
<v Speaker 1>had mega bats as opposed to micro bats, and these

0:14:03.559 --> 0:14:05.959
<v Speaker 1>are large bats that were the are that are found

0:14:05.960 --> 0:14:09.920
<v Speaker 1>in old world tropical rainforests such as Australia, Asia and Africa,

0:14:10.040 --> 0:14:13.480
<v Speaker 1>so dire bats. Yeah. And then the biggest bats in

0:14:13.480 --> 0:14:15.520
<v Speaker 1>the world, and the biggest bat in the world right

0:14:15.520 --> 0:14:19.160
<v Speaker 1>now is the Malayan flying fox found in Asia. It

0:14:19.160 --> 0:14:21.200
<v Speaker 1>weighs about two pounds and has a wingspin of about

0:14:21.240 --> 0:14:24.720
<v Speaker 1>six ft and it eats only fruit. See yeah, and

0:14:24.760 --> 0:14:27.760
<v Speaker 1>people are probably you know, scared of it, I would assume,

0:14:28.720 --> 0:14:31.520
<v Speaker 1>even though it's just you know, eating nectar, eating nectar

0:14:31.520 --> 0:14:35.360
<v Speaker 1>and pooping. I mean, yeah. Um, the flying fox comes

0:14:35.440 --> 0:14:38.000
<v Speaker 1>up a lot in this research. It's one of the

0:14:38.200 --> 0:14:41.600
<v Speaker 1>one of the species that's investigated. Now, the smallest bat

0:14:41.640 --> 0:14:44.480
<v Speaker 1>in the world is kitties hog nose bat, also called

0:14:44.480 --> 0:14:47.040
<v Speaker 1>the bumblebee bat, and it's found in Thailand. Weighs about

0:14:47.040 --> 0:14:50.360
<v Speaker 1>two grams that's about how much of dime ways, and

0:14:50.440 --> 0:14:52.200
<v Speaker 1>it has a six inch wings. But it's like a

0:14:52.280 --> 0:14:55.920
<v Speaker 1>hummingbird bat, any tiny little thing. All right, let's take

0:14:55.920 --> 0:14:58.480
<v Speaker 1>a quick break and when we come back, we will

0:14:58.680 --> 0:15:06.520
<v Speaker 1>jump into the disea. Okay, so we're back. So yeah.

0:15:06.760 --> 0:15:10.440
<v Speaker 1>So there is this just assumption by most people that

0:15:10.760 --> 0:15:13.760
<v Speaker 1>bats carry disease. Right, That's why most people freak out

0:15:13.760 --> 0:15:16.200
<v Speaker 1>when they find a bat in their house. It's like, oh,

0:15:16.240 --> 0:15:19.040
<v Speaker 1>it's gonna spread disease. It's probably got rabies or something. Right,

0:15:19.120 --> 0:15:21.080
<v Speaker 1>we've got a god. I remember this when I was

0:15:21.080 --> 0:15:24.080
<v Speaker 1>like five years old. We were at my uncle's house

0:15:24.360 --> 0:15:26.240
<v Speaker 1>and there was a bat in the attic and he

0:15:26.280 --> 0:15:28.880
<v Speaker 1>had a tennis racket and was like chasing this bat

0:15:28.960 --> 0:15:31.480
<v Speaker 1>around the house with a tennis racket, trying to trying

0:15:31.520 --> 0:15:33.640
<v Speaker 1>to kill it. And I, even at five, I was like,

0:15:33.640 --> 0:15:37.720
<v Speaker 1>why just open the window, man, let this back. Anyway,

0:15:38.000 --> 0:15:41.200
<v Speaker 1>bats are a refuge for some of the world's most

0:15:41.440 --> 0:15:46.400
<v Speaker 1>lethal diseases to humans. That is true. And that includes rabies, Ebola,

0:15:46.760 --> 0:15:50.680
<v Speaker 1>Marburg and stars. Now, because there are many high profile

0:15:50.720 --> 0:15:53.800
<v Speaker 1>epidemics that are traced to bats, we call these bat

0:15:53.880 --> 0:15:57.200
<v Speaker 1>born viruses, and there's a whole line of investigation related

0:15:57.200 --> 0:16:01.520
<v Speaker 1>to bat born viruses. They're similar the way that they

0:16:01.560 --> 0:16:04.280
<v Speaker 1>carry diseases, similar to rats or mice, and that they

0:16:04.280 --> 0:16:08.560
<v Speaker 1>are known as disease reservoirs. But again, they are not rodents,

0:16:08.720 --> 0:16:12.400
<v Speaker 1>so these are very different species. Now, while they seem

0:16:12.440 --> 0:16:17.440
<v Speaker 1>adept at harboring and spreading disease, others argue that this

0:16:17.520 --> 0:16:22.080
<v Speaker 1>notoriety for bats isn't justified. Most of the time, reservoirs

0:16:22.160 --> 0:16:25.360
<v Speaker 1>like bats rarely show symptoms of the disease that they're

0:16:25.360 --> 0:16:28.280
<v Speaker 1>actually infected with. This is why they came up as

0:16:28.280 --> 0:16:31.800
<v Speaker 1>a topic when we were talking about patient zero. Other times,

0:16:31.800 --> 0:16:35.560
<v Speaker 1>the virus infects a new, more vulnerable species like us

0:16:35.640 --> 0:16:39.320
<v Speaker 1>human beings. This is why most research says that bats

0:16:39.360 --> 0:16:43.680
<v Speaker 1>were responsible for the Ebola outbreak in West Africa. Now,

0:16:43.760 --> 0:16:46.400
<v Speaker 1>what's weird is that bats don't seem to die as

0:16:46.480 --> 0:16:50.880
<v Speaker 1>quickly from these viruses. In Ghana, for instance, sixty eight

0:16:51.080 --> 0:16:55.080
<v Speaker 1>percent of fruit bats over ten years old had antibodies

0:16:55.080 --> 0:16:59.000
<v Speaker 1>in their system for the rabies LESA virus, but they

0:16:59.000 --> 0:17:01.760
<v Speaker 1>were all in good health. The same goes for those

0:17:01.800 --> 0:17:05.159
<v Speaker 1>that were carrying a bowla. There was only one presumed

0:17:05.280 --> 0:17:09.080
<v Speaker 1>bat to human transfer of the disease. So there's this

0:17:09.080 --> 0:17:11.280
<v Speaker 1>this fear that the bats are going to spread the

0:17:11.320 --> 0:17:14.360
<v Speaker 1>disease to us, right, and yet there's very little evidence

0:17:14.400 --> 0:17:17.880
<v Speaker 1>that there's bad to human transfer. Uh, but more along

0:17:17.920 --> 0:17:20.200
<v Speaker 1>the lines like we were talking about earlier, that it's

0:17:20.200 --> 0:17:23.360
<v Speaker 1>more like bats. In fact, other animals were encroaching upon

0:17:23.440 --> 0:17:27.760
<v Speaker 1>bat habitats. Therefore we get infected as it transfers from

0:17:27.760 --> 0:17:33.119
<v Speaker 1>animal to animals. Zoonotic infection now obligatory Simpsons reference. UM.

0:17:33.840 --> 0:17:36.480
<v Speaker 1>I remember there being an episode where it's it's explained

0:17:36.520 --> 0:17:40.520
<v Speaker 1>that Mr Burns Uh is still alive because he has

0:17:40.560 --> 0:17:43.000
<v Speaker 1>all of these illnesses that are I think these a

0:17:43.440 --> 0:17:46.200
<v Speaker 1>graphic that shows like all these illnesses trying to squeeze

0:17:46.200 --> 0:17:47.920
<v Speaker 1>through a door at the same time, and none of

0:17:47.960 --> 0:17:49.880
<v Speaker 1>them can get through, and that's why I can't die

0:17:49.920 --> 0:17:52.040
<v Speaker 1>from any of them. That's fascinating. So I can't help

0:17:52.040 --> 0:17:56.160
<v Speaker 1>but think of that, yeah, kind of Uh. In Australia,

0:17:56.440 --> 0:18:00.160
<v Speaker 1>thirty flying foxes. I told you they'd come up add

0:18:00.200 --> 0:18:03.959
<v Speaker 1>antibodies to the Hendra virus, and this indicated that they

0:18:03.960 --> 0:18:06.679
<v Speaker 1>had been infected with it at some point, but only

0:18:06.880 --> 0:18:10.399
<v Speaker 1>three percent at any given time we're actually carrying it,

0:18:10.680 --> 0:18:13.280
<v Speaker 1>so that's a small amount compared to the amount that

0:18:13.320 --> 0:18:17.080
<v Speaker 1>had been infected. The infected bats themselves had low levels

0:18:17.080 --> 0:18:20.160
<v Speaker 1>of this pathogen, indicating that they were somehow keeping it

0:18:20.240 --> 0:18:25.200
<v Speaker 1>at bay. Subsequently, it's really rare for the Hendra disease

0:18:25.600 --> 0:18:29.840
<v Speaker 1>to pass even from bats to horses. However, in eleven

0:18:30.000 --> 0:18:34.159
<v Speaker 1>it leapt over in twenty four cases, and the theory

0:18:34.200 --> 0:18:37.520
<v Speaker 1>for that is because the bats were stressed out uh

0:18:37.560 --> 0:18:40.320
<v Speaker 1>and that the this caused a surge in the level

0:18:40.359 --> 0:18:42.800
<v Speaker 1>of viruses that the bats were carrying and subsequently made

0:18:42.800 --> 0:18:44.880
<v Speaker 1>it easier for them to pass it on to horses.

0:18:45.320 --> 0:18:47.240
<v Speaker 1>This is going to be important later when we talk

0:18:47.320 --> 0:18:51.040
<v Speaker 1>about uh massive culing of bats when people go, oh,

0:18:51.080 --> 0:18:53.719
<v Speaker 1>their disease carriers. We've got to wipe them out, go

0:18:53.880 --> 0:18:56.200
<v Speaker 1>destroy their colonies, right or else they're going to give

0:18:56.240 --> 0:18:59.200
<v Speaker 1>us these diseases. That could only make things worse because

0:18:59.240 --> 0:19:02.080
<v Speaker 1>then you're stressing out the bat population, which makes the

0:19:02.119 --> 0:19:05.440
<v Speaker 1>diseases become even more powerful. Now, I want to throw

0:19:05.440 --> 0:19:08.639
<v Speaker 1>in a note on vampire bats here as well. So Um,

0:19:08.680 --> 0:19:11.200
<v Speaker 1>the author of Bill Shoot has a wonderful book titled

0:19:11.280 --> 0:19:15.480
<v Speaker 1>Dark Banquet that deals with vampiric organisms in general, but

0:19:15.560 --> 0:19:17.720
<v Speaker 1>a lot of it deals with bats. It's also a

0:19:17.800 --> 0:19:21.800
<v Speaker 1>vampire the gathering RPG men. It could be if you

0:19:21.840 --> 0:19:25.240
<v Speaker 1>want to do a very science oriented campaign. He also

0:19:25.240 --> 0:19:26.919
<v Speaker 1>has a book on cannibals out that I have not

0:19:27.000 --> 0:19:29.959
<v Speaker 1>read anyway. In the book, he points out that vampire

0:19:29.960 --> 0:19:33.280
<v Speaker 1>bats introduced the additional threat of a disease promoting wound.

0:19:33.520 --> 0:19:36.640
<v Speaker 1>The host survives the feeding, but the wound invites additional

0:19:36.760 --> 0:19:40.960
<v Speaker 1>organisms and infections. The bigger concern though, is going to

0:19:41.080 --> 0:19:44.040
<v Speaker 1>be raybies. So it's not the most deadly or the

0:19:44.080 --> 0:19:47.960
<v Speaker 1>most common batborn illness, but if the infection takes hold,

0:19:48.000 --> 0:19:52.760
<v Speaker 1>it's essentially fatal in humans and and and rather infamous

0:19:52.800 --> 0:19:57.160
<v Speaker 1>as well. Um, you know of all the pathogens affecting

0:19:57.240 --> 0:20:03.480
<v Speaker 1>humans and in bat populations overall, um rabies sero prevalence,

0:20:03.520 --> 0:20:05.880
<v Speaker 1>that's a number of persons in a population who test

0:20:05.920 --> 0:20:10.760
<v Speaker 1>positive for specific disease can reach fift And you have

0:20:10.800 --> 0:20:12.960
<v Speaker 1>some notes here about Trinidad. We were talking a little

0:20:12.960 --> 0:20:16.080
<v Speaker 1>bit about this earlier because of some Trinidadian folklore, there's

0:20:16.080 --> 0:20:18.800
<v Speaker 1>bats all over the place down there. Yeah and uh.

0:20:18.800 --> 0:20:21.240
<v Speaker 1>And this is an account that to Shoot mentions in

0:20:21.280 --> 0:20:25.040
<v Speaker 1>his book that I think is interesting. It definitely involves

0:20:25.080 --> 0:20:29.920
<v Speaker 1>both bats and disease, but also superstitions attempts to call

0:20:30.000 --> 0:20:35.240
<v Speaker 1>bat populations. So in Trinidad, bat transmitted rabies killed eighty

0:20:35.320 --> 0:20:38.919
<v Speaker 1>nine people and thousands of cattle between n and nineteen

0:20:38.920 --> 0:20:43.280
<v Speaker 1>thirty four. In thirty four, that's when the Trinidadian Medical

0:20:43.280 --> 0:20:46.520
<v Speaker 1>Department rolled out its anti rabies unit, and their job

0:20:46.640 --> 0:20:50.760
<v Speaker 1>was to respond to vampire bat attacks net and destroy

0:20:50.800 --> 0:20:54.440
<v Speaker 1>the vamps. So they they painted uh that they did

0:20:54.440 --> 0:20:57.520
<v Speaker 1>this by not only killing the bats on the side,

0:20:57.520 --> 0:21:01.720
<v Speaker 1>but they also painted poisonous paint on vampire bat decimating colonies.

0:21:01.760 --> 0:21:06.160
<v Speaker 1>It was a rough situation. Well, and I immediately think

0:21:06.200 --> 0:21:08.680
<v Speaker 1>to the current science and wonder, I wonder how much

0:21:08.680 --> 0:21:11.800
<v Speaker 1>they stressed out the bat population, further spreading disease. The

0:21:11.880 --> 0:21:15.719
<v Speaker 1>human think they certainly did, And Shoot points out that

0:21:15.920 --> 0:21:19.399
<v Speaker 1>superstition played apart in this as well. So local Trinidating

0:21:19.400 --> 0:21:24.439
<v Speaker 1>and the folklore told of creatures called suk unts, and

0:21:24.480 --> 0:21:28.080
<v Speaker 1>these are crones or hags that can shed their skin

0:21:28.119 --> 0:21:31.520
<v Speaker 1>at night and become a fiery, blood sucking ball and

0:21:31.520 --> 0:21:35.159
<v Speaker 1>you sprinkle rice on your doorstep to keep them away. Now,

0:21:35.560 --> 0:21:37.840
<v Speaker 1>there were also conservationists at the time, and they could

0:21:38.000 --> 0:21:40.840
<v Speaker 1>they combated the folklore and the general you know, fear

0:21:40.880 --> 0:21:43.760
<v Speaker 1>of disease associated with bats by spreading the message that look,

0:21:44.480 --> 0:21:47.480
<v Speaker 1>there are only two out of fifty eight bat species

0:21:47.520 --> 0:21:50.080
<v Speaker 1>on the island that are vampires, and if those two

0:21:50.359 --> 0:21:54.840
<v Speaker 1>only the common vampire bat or does Modus rotundus is

0:21:54.880 --> 0:21:59.080
<v Speaker 1>a significant rabies threat. Okay, So that yeah, so that

0:21:59.119 --> 0:22:02.840
<v Speaker 1>definitely sounds a situation where the fear of bats sort

0:22:02.840 --> 0:22:05.720
<v Speaker 1>of got the better of the human population and maybe

0:22:05.720 --> 0:22:09.280
<v Speaker 1>made the problem worse. So we've we've really outlined here

0:22:09.320 --> 0:22:12.680
<v Speaker 1>that Okay, these bats carry all these diseases, they don't

0:22:12.680 --> 0:22:15.560
<v Speaker 1>seem to be affected by it too much. What's the deal?

0:22:16.240 --> 0:22:20.879
<v Speaker 1>And you know, subsequently, why then does it transfer? Okay, well,

0:22:21.400 --> 0:22:25.280
<v Speaker 1>it seems like bats have superimmune systems. Again, something you

0:22:25.320 --> 0:22:28.240
<v Speaker 1>would think that Batman would have his power, right, like,

0:22:28.240 --> 0:22:29.920
<v Speaker 1>like that would be a cool power. He just never

0:22:29.960 --> 0:22:32.359
<v Speaker 1>gets I guess Batman just never gets sick anyway, because

0:22:32.359 --> 0:22:37.080
<v Speaker 1>but it's not like any villains are trying. Yeah, well,

0:22:37.160 --> 0:22:39.880
<v Speaker 1>that's kind of why the bats turns out have such

0:22:39.880 --> 0:22:43.080
<v Speaker 1>great immune systems. There's two schools of thought here, okay,

0:22:43.359 --> 0:22:48.040
<v Speaker 1>on whether bats actually carry a disproportionately high number of viruses.

0:22:48.320 --> 0:22:51.040
<v Speaker 1>The first school of thought goes like this, bat related

0:22:51.040 --> 0:22:55.320
<v Speaker 1>epidemics arise because there are so many species of bats,

0:22:55.400 --> 0:22:58.840
<v Speaker 1>and there's so many individual bats, that the emergence of

0:22:58.880 --> 0:23:03.199
<v Speaker 1>all these various diseases isn't surprising. Like Robert said at

0:23:03.200 --> 0:23:07.000
<v Speaker 1>the top, there's more than bats species. Bats comprise more

0:23:07.040 --> 0:23:10.400
<v Speaker 1>than twenty of the mammals on Earth. A single colony

0:23:10.480 --> 0:23:13.320
<v Speaker 1>can sometimes have millions of bats living in it, and

0:23:13.359 --> 0:23:17.400
<v Speaker 1>there may be a massive amount of bat diversity right.

0:23:17.800 --> 0:23:21.760
<v Speaker 1>And study on the Indian flying fox that giant bat

0:23:22.240 --> 0:23:26.880
<v Speaker 1>fifty five viruses were detected in its system. Fifty were

0:23:27.000 --> 0:23:31.919
<v Speaker 1>previously unknown, so they're carrying a lot. That's just one species.

0:23:32.640 --> 0:23:37.160
<v Speaker 1>We may be hearing about bat born epidemics more often

0:23:37.800 --> 0:23:40.879
<v Speaker 1>simply because of how humans are interacting with bats. Right,

0:23:40.920 --> 0:23:44.919
<v Speaker 1>We're encroaching it on their habitats. Subsequently, they suffer from

0:23:44.920 --> 0:23:48.320
<v Speaker 1>the stigma of being disease written and likewise, bats are

0:23:48.359 --> 0:23:51.520
<v Speaker 1>surveyed more often and are easier to catch than other

0:23:51.600 --> 0:23:55.520
<v Speaker 1>mammals too, so subsequently we're again interacting with them more,

0:23:55.640 --> 0:24:00.520
<v Speaker 1>maybe for studies. So some conservationists argue that the viruses

0:24:00.560 --> 0:24:04.719
<v Speaker 1>they carry aren't actually emerging infectious diseases, but they're simply

0:24:04.800 --> 0:24:08.160
<v Speaker 1>just new to us as human beings. And let's remember

0:24:08.160 --> 0:24:11.440
<v Speaker 1>to bats live in those packed colonies, right, so it's

0:24:11.520 --> 0:24:14.480
<v Speaker 1>super easy for them to pass viruses onto one another.

0:24:14.840 --> 0:24:19.880
<v Speaker 1>They also can fly thousands of kilometers, which subsequently makes

0:24:19.880 --> 0:24:24.679
<v Speaker 1>it easier for them to deliver viruses to further distances. Okay,

0:24:24.760 --> 0:24:29.679
<v Speaker 1>that's the first theory. Here's the second, like wolverine healing

0:24:29.800 --> 0:24:36.000
<v Speaker 1>factor immune systems theory. Okay, bats have a special physiology

0:24:36.040 --> 0:24:41.040
<v Speaker 1>and lifestyle that makes them exceptionally good at hosting viruses.

0:24:41.720 --> 0:24:45.400
<v Speaker 1>Bats live between three and ten times longer than other

0:24:45.480 --> 0:24:48.400
<v Speaker 1>mammals their size, and we used to think that this

0:24:48.600 --> 0:24:51.720
<v Speaker 1>was because of hibernation, but there's there's been a lot

0:24:51.760 --> 0:24:54.800
<v Speaker 1>more research into this lately. If you inject a bat

0:24:55.160 --> 0:24:58.880
<v Speaker 1>with bacterial toxins that would normally trigger an immune response

0:24:58.920 --> 0:25:02.840
<v Speaker 1>in mammals, a bat will have no fever and no

0:25:03.080 --> 0:25:07.960
<v Speaker 1>spike in white blood cells. Now, research published in shows

0:25:08.000 --> 0:25:11.680
<v Speaker 1>that while bat genomes contain many of the same ingredients

0:25:11.680 --> 0:25:15.879
<v Speaker 1>as other mammals. Bats use these genomes differently. Bat genes

0:25:16.400 --> 0:25:22.320
<v Speaker 1>coding for proteins detect and repaired damaged DNA, and they

0:25:22.320 --> 0:25:25.680
<v Speaker 1>are much more prevalent than we had previously thought. So

0:25:25.840 --> 0:25:28.520
<v Speaker 1>this new line of thinking is that bat genes are

0:25:28.520 --> 0:25:31.720
<v Speaker 1>doing something that helps them survive and reproduce, and that

0:25:31.760 --> 0:25:36.240
<v Speaker 1>they subsequently pass these awesome genes along to subsequent generations.

0:25:37.640 --> 0:25:40.800
<v Speaker 1>So those same DNA repair genes that I was talking

0:25:40.800 --> 0:25:44.680
<v Speaker 1>about are frequently the targets for invading viruses. In fact,

0:25:45.200 --> 0:25:49.399
<v Speaker 1>key genes and DNA damage repair are also involved in

0:25:49.520 --> 0:25:54.440
<v Speaker 1>tumor development and immunity, and this might be why bats

0:25:54.480 --> 0:25:57.800
<v Speaker 1>are evolving in such a way. Now here's a crazy anecdote.

0:25:58.160 --> 0:26:03.240
<v Speaker 1>Bats almost never developed tumors. Perhaps this is because these

0:26:03.240 --> 0:26:07.600
<v Speaker 1>repair genes are just constantly outpacing malignant growths. They almost

0:26:07.760 --> 0:26:11.800
<v Speaker 1>never get cancer. When you give them tumor causing drugs,

0:26:11.840 --> 0:26:15.359
<v Speaker 1>they're less likely to develop cancer than other mammals, So

0:26:15.400 --> 0:26:20.439
<v Speaker 1>that's pretty wild. In humans and mice, defenses like these

0:26:20.520 --> 0:26:24.000
<v Speaker 1>repair genes, those are activated in response to a threat, right,

0:26:24.119 --> 0:26:26.360
<v Speaker 1>So uh, sort of like we're talking about in our

0:26:26.359 --> 0:26:30.280
<v Speaker 1>other episode this week. You know, it's a stimulised system.

0:26:30.320 --> 0:26:34.560
<v Speaker 1>If you have a trigger, it activates it. In this case,

0:26:34.720 --> 0:26:38.200
<v Speaker 1>in bats, it seems to be perpetually turned on. Their

0:26:38.240 --> 0:26:41.679
<v Speaker 1>immune system is just always on, and that might be

0:26:41.800 --> 0:26:45.080
<v Speaker 1>why the viruses they carry are kept below a point

0:26:45.280 --> 0:26:49.680
<v Speaker 1>where they can actually harm their host. Also, bats seem

0:26:49.760 --> 0:26:53.600
<v Speaker 1>to have lost an entire branch of their immune system

0:26:53.640 --> 0:26:57.080
<v Speaker 1>that's made up of inflammas homes. These are the receptors

0:26:57.119 --> 0:27:00.640
<v Speaker 1>and sensors that induce inflammation, so they've all to turn

0:27:00.760 --> 0:27:04.760
<v Speaker 1>down their inflammatory response to various threats, including viruses. So

0:27:04.840 --> 0:27:08.040
<v Speaker 1>basically bats are just like, ain't no big thing I've

0:27:08.040 --> 0:27:11.760
<v Speaker 1>got I've got fifty viruses in me right now, right now.

0:27:11.760 --> 0:27:14.880
<v Speaker 1>Why you're probably going, well, why bats and not me? Right?

0:27:16.520 --> 0:27:20.199
<v Speaker 1>The thought here is is because of the high metabolic

0:27:20.440 --> 0:27:24.280
<v Speaker 1>rate bats have to keep up to maintain their energy

0:27:24.320 --> 0:27:28.400
<v Speaker 1>they produce while they're flying. Otherwise, the stress of flying

0:27:28.440 --> 0:27:31.199
<v Speaker 1>itself would damage their cells and their DNA if it

0:27:31.240 --> 0:27:34.439
<v Speaker 1>wasn't so quickly detected and repaired. So the ability to

0:27:34.600 --> 0:27:38.320
<v Speaker 1>carry all these lethal viruses may come actually as a

0:27:38.400 --> 0:27:42.280
<v Speaker 1>co evolutionary accident. Bats are the only mammals that are

0:27:42.280 --> 0:27:45.840
<v Speaker 1>capable of powered flight, which is super demanding in terms

0:27:45.840 --> 0:27:49.359
<v Speaker 1>of energy, and it subsequently is very tough on their metabolism.

0:27:49.400 --> 0:27:52.399
<v Speaker 1>A bat's heart can beat over a thousand times a

0:27:52.440 --> 0:27:55.160
<v Speaker 1>minute if they need it to, and their metabolic rate

0:27:55.200 --> 0:27:59.159
<v Speaker 1>in the air increases thirty four times. When you compare

0:27:59.200 --> 0:28:03.480
<v Speaker 1>that to rodents, again not the same species, but exercising rodents,

0:28:03.920 --> 0:28:06.840
<v Speaker 1>they only jump up to eight times their metabolic rate.

0:28:07.320 --> 0:28:10.280
<v Speaker 1>When your metabolism is as ramped up as bats are,

0:28:10.480 --> 0:28:14.520
<v Speaker 1>it spews out free radicals, and these are energetic particles

0:28:14.560 --> 0:28:18.960
<v Speaker 1>that can damage cells and kickstart inflammation. So it's possible

0:28:19.040 --> 0:28:23.800
<v Speaker 1>that bats evolved specifically for flight and that that just

0:28:24.240 --> 0:28:30.160
<v Speaker 1>casually also allows them to avoid overreacting to viral infections. Now,

0:28:30.200 --> 0:28:33.000
<v Speaker 1>another note on vampire bats. I think we've touched on

0:28:33.000 --> 0:28:35.960
<v Speaker 1>this in the past, and we've discussed real world vampires,

0:28:36.760 --> 0:28:39.440
<v Speaker 1>but but this makes the vampire bat situation even crazier.

0:28:39.480 --> 0:28:42.560
<v Speaker 1>They have this crazy metabolism to deal with the costs

0:28:42.640 --> 0:28:45.400
<v Speaker 1>of high costs of powered flight, and they're depending on

0:28:45.680 --> 0:28:49.560
<v Speaker 1>the nutrient deprived feast of blood power everything. Right. This

0:28:49.640 --> 0:28:52.560
<v Speaker 1>is like if you met somebody and you sit and

0:28:52.560 --> 0:28:54.040
<v Speaker 1>you ask them, hey, what are you into and what

0:28:54.040 --> 0:28:56.640
<v Speaker 1>do you do for a living and they say, well, uh,

0:28:56.680 --> 0:29:00.600
<v Speaker 1>I have I have a hobby of mine is just

0:29:00.680 --> 0:29:05.200
<v Speaker 1>collecting really expensive wines, and my profession is hot dog

0:29:05.200 --> 0:29:07.800
<v Speaker 1>photography only hot dog photography. And you're like, ooh, I

0:29:07.800 --> 0:29:10.040
<v Speaker 1>don't know, guy, that sounds like you've got a really

0:29:10.040 --> 0:29:16.880
<v Speaker 1>expensive hobby and and an extremely specific career here that

0:29:16.920 --> 0:29:21.760
<v Speaker 1>I can't imagine pays the dividends necessary. Yeah. Yeah, Well,

0:29:21.880 --> 0:29:26.280
<v Speaker 1>the idea about the bat immune system seems to be

0:29:26.320 --> 0:29:29.680
<v Speaker 1>supported when we look at their mitochondria. It seems that

0:29:29.720 --> 0:29:34.680
<v Speaker 1>their mitochondria has undergone more evolutionary changes than the mitochondria

0:29:34.760 --> 0:29:38.560
<v Speaker 1>that's in other mammals. Individual bats have an assortment of

0:29:38.640 --> 0:29:42.400
<v Speaker 1>mitochondria rather than the way that most organisms like us

0:29:42.440 --> 0:29:45.360
<v Speaker 1>have just carbon copies of it. This seems to help

0:29:45.440 --> 0:29:48.840
<v Speaker 1>them deal with the damaging free radicals that are produced

0:29:48.960 --> 0:29:52.920
<v Speaker 1>during flight, all of which can explain their long lives.

0:29:53.080 --> 0:29:57.480
<v Speaker 1>The tumor resistance and more. Bat mitochondria also might be

0:29:57.600 --> 0:30:01.360
<v Speaker 1>like these crucial command centers that sent and decide whether

0:30:01.400 --> 0:30:04.520
<v Speaker 1>a cell should fight or just self destruct. So they've

0:30:04.520 --> 0:30:07.800
<v Speaker 1>got they've really got this, like, uh, you know, to

0:30:07.880 --> 0:30:10.160
<v Speaker 1>use the same metaphor that we're using in this week's

0:30:10.200 --> 0:30:14.200
<v Speaker 1>Demon episode, like they've got a great home security system

0:30:14.800 --> 0:30:17.120
<v Speaker 1>when it's all like you know, in terms of dealing

0:30:17.120 --> 0:30:22.440
<v Speaker 1>with viruses, dealing with the metabolic breakdown in their system, etcetera.

0:30:23.080 --> 0:30:26.480
<v Speaker 1>Another hypothesis that's related to bat flight, though generate, is

0:30:26.520 --> 0:30:30.320
<v Speaker 1>that they generate so much heat that it actually mimics

0:30:30.320 --> 0:30:34.080
<v Speaker 1>a fever. Now, you know, fever's combat infection by raising

0:30:34.080 --> 0:30:36.800
<v Speaker 1>our body temperature to levels that will kill or disable

0:30:36.880 --> 0:30:41.720
<v Speaker 1>any invading pathogen. But maybe bat's body temperatures are so

0:30:41.840 --> 0:30:46.840
<v Speaker 1>high when they fly that they're just inadvertently killing viruses off. Yeah,

0:30:46.920 --> 0:30:50.000
<v Speaker 1>this is an interesting take on on bat immunities. Um,

0:30:50.280 --> 0:30:53.320
<v Speaker 1>there's a two thousand fifteen study Publishment Biology Letters that

0:30:54.040 --> 0:30:56.240
<v Speaker 1>that hypothesize that a lot of it, I could come

0:30:56.280 --> 0:30:58.960
<v Speaker 1>down to these drastic temperature changes over the course of

0:30:59.040 --> 0:31:01.680
<v Speaker 1>just a single day. So a bat sleeps in the day,

0:31:01.960 --> 0:31:06.320
<v Speaker 1>temperature drops to conserve energy, then slows the pathogen spread

0:31:06.360 --> 0:31:08.800
<v Speaker 1>in the process, and then it goes out to hunt,

0:31:09.200 --> 0:31:12.200
<v Speaker 1>in which case it's temperatures exceed a hundred degrees fahrenheit.

0:31:12.480 --> 0:31:17.000
<v Speaker 1>And this which basically involves a daily fever to increase

0:31:17.040 --> 0:31:22.160
<v Speaker 1>the activity of certain immune sets. Yeah, so the fascinating

0:31:22.200 --> 0:31:26.280
<v Speaker 1>stuff that uh, is not incorporated into Batman lawyer. Batman

0:31:26.280 --> 0:31:28.760
<v Speaker 1>doesn't have a fever, or he's not like burning up

0:31:29.000 --> 0:31:31.960
<v Speaker 1>with he's burning up with rage at the death of

0:31:32.000 --> 0:31:35.120
<v Speaker 1>his parents. That's true. Now here's another interesting thing about

0:31:35.120 --> 0:31:39.800
<v Speaker 1>bat metabolism. So they're heterotherms, meaning they can exhibit characteristics

0:31:39.800 --> 0:31:42.840
<v Speaker 1>of both warm and cold blooded organisms. But they're distinct

0:31:42.880 --> 0:31:45.960
<v Speaker 1>from all other heterotherms in that, no matter what the

0:31:46.000 --> 0:31:50.320
<v Speaker 1>season they're resting temperature and metabolic rate is dependent on

0:31:50.360 --> 0:31:53.720
<v Speaker 1>a non ambient temperature. They're the only mammals in which

0:31:54.040 --> 0:31:56.760
<v Speaker 1>the resting metabolism is a direct function of the body

0:31:56.800 --> 0:32:01.400
<v Speaker 1>temperature rather than the ambient temperature. And that came from

0:32:01.040 --> 0:32:04.800
<v Speaker 1>an article by Raymond J. Hawk, the metabolic rates and

0:32:04.840 --> 0:32:08.360
<v Speaker 1>body temperatures of bats. And some of you are probably wondering, well, okay,

0:32:08.400 --> 0:32:10.880
<v Speaker 1>bats fly, but so do all those other creatures that

0:32:10.920 --> 0:32:14.440
<v Speaker 1>you mentioned earlier. What about birds? You know, do birds

0:32:14.440 --> 0:32:17.719
<v Speaker 1>have the same superpower? Well, birds are also long lived,

0:32:17.760 --> 0:32:21.720
<v Speaker 1>and that's possibly because flight enables them to just evade predators.

0:32:21.760 --> 0:32:26.440
<v Speaker 1>But uh, it's also because flight increase their chances of

0:32:26.560 --> 0:32:30.240
<v Speaker 1>developing a mechanism to reduce cellular damage. Very similar, right,

0:32:30.240 --> 0:32:33.560
<v Speaker 1>So the metabolic thing is similar. I don't know necessarily

0:32:33.560 --> 0:32:38.160
<v Speaker 1>that the body temperature thing equals out, probably because uh,

0:32:38.240 --> 0:32:42.960
<v Speaker 1>we're talking about mammals versus birds, totally different anatomies. Either way,

0:32:43.240 --> 0:32:46.920
<v Speaker 1>some scientists still worry that bat born viruses are so

0:32:47.080 --> 0:32:52.200
<v Speaker 1>lethal because they've evolved to withstand the bats incredibly active

0:32:52.200 --> 0:32:56.200
<v Speaker 1>immune system. But if they transferred humans, right, so, like

0:32:56.360 --> 0:32:59.920
<v Speaker 1>rabies or a bola, these viruses are super well at

0:33:00.000 --> 0:33:04.640
<v Speaker 1>whip to defeat our weaker immune systems. So subsequently, that's

0:33:04.640 --> 0:33:07.080
<v Speaker 1>why we have such a hard time dealing with these Wow.

0:33:07.120 --> 0:33:10.600
<v Speaker 1>So in in the Dune universe, the bat would be

0:33:10.640 --> 0:33:13.719
<v Speaker 1>like a hell world where you where you evolve and

0:33:13.760 --> 0:33:19.800
<v Speaker 1>develop a highly effective mode of shock troops. Yeah. Alright,

0:33:19.880 --> 0:33:21.800
<v Speaker 1>let's take another break, and when we get back, we're

0:33:21.800 --> 0:33:25.120
<v Speaker 1>going to close out by talking about, hey, don't kill

0:33:25.160 --> 0:33:27.800
<v Speaker 1>those bats because we might be able to use them

0:33:27.840 --> 0:33:35.120
<v Speaker 1>to lead to improvements in our health. Alright, we're back,

0:33:35.160 --> 0:33:38.400
<v Speaker 1>so so hit me, Christian, how how can we potentially

0:33:38.440 --> 0:33:40.560
<v Speaker 1>become more bat like? Am I gonna need a telepod

0:33:41.080 --> 0:33:43.440
<v Speaker 1>and a bat and we're going to splice ourselves together

0:33:43.480 --> 0:33:45.600
<v Speaker 1>into a man bat? Yeah? You know, that seems like

0:33:45.680 --> 0:33:47.600
<v Speaker 1>one way that would work pretty well. But it would

0:33:47.680 --> 0:33:50.240
<v Speaker 1>you know, like like with Man bat you would kind

0:33:50.240 --> 0:33:53.160
<v Speaker 1>of like lose total control of your personality and probably

0:33:53.240 --> 0:33:56.520
<v Speaker 1>murder your wife. But uh, and you wouldn't want to

0:33:56.560 --> 0:33:58.960
<v Speaker 1>do the Batman thing because, like we said, Batman, it's

0:33:59.000 --> 0:34:00.440
<v Speaker 1>just a guy in a cost you him. He's got

0:34:00.520 --> 0:34:03.880
<v Speaker 1>some gadgets. He's not really uh you know, cranking up

0:34:03.880 --> 0:34:07.120
<v Speaker 1>the metabolism. He isn't ever great immune system man Bat

0:34:07.160 --> 0:34:10.120
<v Speaker 1>for anyone listening is not familiar is of the the

0:34:10.280 --> 0:34:16.200
<v Speaker 1>bat human hybrid in the Batman comics. I remember, he's

0:34:16.239 --> 0:34:18.200
<v Speaker 1>kind of what you think of when you first hear

0:34:18.239 --> 0:34:20.960
<v Speaker 1>Batman's that, like he would it's like a wear bat

0:34:21.440 --> 0:34:25.799
<v Speaker 1>with like a ripped blue jeans totally. Yeah. Yeah. Um. Now,

0:34:25.840 --> 0:34:29.600
<v Speaker 1>as a result of recent viruses, whole bat colonies are

0:34:29.640 --> 0:34:31.879
<v Speaker 1>being killed off in the name of public health, as

0:34:31.880 --> 0:34:35.440
<v Speaker 1>we mentioned earlier, and experts say, look, we shouldn't be

0:34:35.480 --> 0:34:40.280
<v Speaker 1>afraid of bats because the viruses they carry comparatively hardly

0:34:40.320 --> 0:34:43.960
<v Speaker 1>ever transmit to human beings. In fact, killing bats may

0:34:44.000 --> 0:34:46.640
<v Speaker 1>make things worse. Like I mentioned, the stress on the

0:34:46.680 --> 0:34:50.719
<v Speaker 1>remaining bats could actually raise their viral loads, which could

0:34:50.800 --> 0:34:56.040
<v Speaker 1>lead to more transference to other animals. But what if

0:34:56.080 --> 0:34:59.400
<v Speaker 1>bats could hold the key to improving human health and

0:34:59.440 --> 0:35:02.759
<v Speaker 1>allowing us to live longer. Well, if we look at

0:35:02.840 --> 0:35:05.239
<v Speaker 1>knowledge and we try to figure it out how their

0:35:05.239 --> 0:35:08.360
<v Speaker 1>immune systems work, and that leads to the development of

0:35:08.480 --> 0:35:11.239
<v Speaker 1>drugs that would improve our health and lifespan, that's one

0:35:11.280 --> 0:35:13.560
<v Speaker 1>way that we could do it. So we basically reverse

0:35:13.600 --> 0:35:17.320
<v Speaker 1>engineer those proteins and then we turn it into medicine,

0:35:18.000 --> 0:35:21.480
<v Speaker 1>or we could use gene editing technology to make human

0:35:21.600 --> 0:35:26.560
<v Speaker 1>genomes more like bats, which would give us similar immune

0:35:26.560 --> 0:35:31.160
<v Speaker 1>system properties. Although I have to wonder if there would

0:35:31.200 --> 0:35:34.640
<v Speaker 1>be some kind of like drawback with that in the

0:35:34.680 --> 0:35:38.200
<v Speaker 1>sense that like, if your metabolism was that fast but

0:35:38.239 --> 0:35:41.120
<v Speaker 1>you weren't flying all the time, wouldn't you just be

0:35:41.239 --> 0:35:46.319
<v Speaker 1>constantly like hungry, I mean, so you'd have to eat

0:35:46.320 --> 0:35:49.720
<v Speaker 1>a lot more. Um. Maybe that's where we start eating bugs.

0:35:50.840 --> 0:35:55.440
<v Speaker 1>Researchers are also trying to identify the proteins that specifically

0:35:55.480 --> 0:35:59.440
<v Speaker 1>allow bats to control inflammation and other processes that are

0:35:59.440 --> 0:36:02.640
<v Speaker 1>associated with disease. So it's possible that we could one

0:36:02.719 --> 0:36:05.799
<v Speaker 1>day use these proteins or a version of them to

0:36:06.040 --> 0:36:09.200
<v Speaker 1>treat disorders where inflammation is a problem, like, for instance,

0:36:09.280 --> 0:36:14.000
<v Speaker 1>rheumatoid arthritis or heart disease. So we could use these

0:36:14.040 --> 0:36:18.759
<v Speaker 1>to stop viruses like a bola also from killing us. Like,

0:36:18.800 --> 0:36:23.239
<v Speaker 1>if we figure out how the bat system works, then

0:36:23.320 --> 0:36:27.000
<v Speaker 1>we apply it to the human anatomy system, we could

0:36:27.000 --> 0:36:30.440
<v Speaker 1>potentially be resistant to a bola and rabies in the

0:36:30.480 --> 0:36:33.520
<v Speaker 1>same way that they are, or maybe other viruses that

0:36:33.560 --> 0:36:36.440
<v Speaker 1>we haven't even discovered yet. So to bring it back

0:36:36.440 --> 0:36:39.400
<v Speaker 1>to Batman, you do have to to I guess acknowledge

0:36:39.440 --> 0:36:42.800
<v Speaker 1>that Batman, if nothing else, he's long lived, He's resistant

0:36:42.800 --> 0:36:45.440
<v Speaker 1>to illness and death. You have if you've taken to

0:36:45.440 --> 0:36:47.640
<v Speaker 1>account of the character hit comic book stands for the

0:36:47.640 --> 0:36:51.680
<v Speaker 1>first time in nine and assuming Wayne was what at

0:36:51.719 --> 0:36:55.320
<v Speaker 1>least twenty at the time, He's still going strong today

0:36:55.360 --> 0:36:58.359
<v Speaker 1>at close to a hundred over a hundred years old. Yeah,

0:36:58.400 --> 0:37:04.160
<v Speaker 1>Ben Affleck doesn't look good day over nine. Yeah, I

0:37:04.160 --> 0:37:07.000
<v Speaker 1>mean that speaks to the power of the mythology I

0:37:07.040 --> 0:37:10.440
<v Speaker 1>think of Batman in popular culture for sure, but yeah,

0:37:10.680 --> 0:37:15.239
<v Speaker 1>it's definitely it seems like Batman and other superheroes are

0:37:15.480 --> 0:37:19.880
<v Speaker 1>certainly long lived, but there's no explanation in the the

0:37:19.880 --> 0:37:23.440
<v Speaker 1>the meta text of why Batman has been around for

0:37:23.480 --> 0:37:25.840
<v Speaker 1>so long right, even in like some of them, Like

0:37:25.880 --> 0:37:28.400
<v Speaker 1>there's a do you remember Batman Beyond that cartoon that

0:37:28.520 --> 0:37:30.799
<v Speaker 1>was like set in the future. Yeah, and he's so

0:37:31.200 --> 0:37:33.239
<v Speaker 1>now you have the old Bruce Wayne. Because this is

0:37:33.239 --> 0:37:35.600
<v Speaker 1>gonna be my next question. What is the oldest depiction

0:37:36.000 --> 0:37:40.319
<v Speaker 1>of Bruce Wayne and or Batman in a comic book

0:37:40.360 --> 0:37:43.200
<v Speaker 1>or cartoon? Yeah, I think it's that um and in

0:37:43.320 --> 0:37:46.840
<v Speaker 1>that Even then, he's still kind of a badass, uh

0:37:46.840 --> 0:37:49.359
<v Speaker 1>in the bat Dog comes up in that because he's

0:37:49.400 --> 0:37:52.200
<v Speaker 1>got a um ace. The bath Hound hangs out with

0:37:52.280 --> 0:37:55.120
<v Speaker 1>him in the cave all the time. But there's also

0:37:55.120 --> 0:37:58.279
<v Speaker 1>another depiction. I think it's in Kingdom Come, which is

0:37:58.360 --> 0:38:02.640
<v Speaker 1>a sort of alternate universe story. Again older Batman, but

0:38:02.760 --> 0:38:05.560
<v Speaker 1>he like we're more like sort of like an Iron

0:38:05.560 --> 0:38:09.240
<v Speaker 1>Man armor version of like the Batman's suit that allows

0:38:09.320 --> 0:38:12.560
<v Speaker 1>him to go out and uh fight crime and deal

0:38:12.600 --> 0:38:16.440
<v Speaker 1>with other superheroes and stuff. Old dude in a power

0:38:16.520 --> 0:38:21.359
<v Speaker 1>armors basically Yeah, okay, interesting, alright, but none of it

0:38:21.480 --> 0:38:26.160
<v Speaker 1>had to do with his metabolism or gene editing. Alright, Well,

0:38:26.400 --> 0:38:28.640
<v Speaker 1>well there you have it. We've talked about the bats,

0:38:28.719 --> 0:38:32.359
<v Speaker 1>bats and diseases. We've gone back and forth a little

0:38:32.400 --> 0:38:35.400
<v Speaker 1>bit about Batman, and now we we leave it to you,

0:38:35.480 --> 0:38:38.399
<v Speaker 1>we ask you for feedback. Yeah, so you know, let

0:38:38.480 --> 0:38:40.439
<v Speaker 1>us know. I want to make sure that we gave

0:38:40.480 --> 0:38:42.279
<v Speaker 1>bats a fair shake. Let us know if you feel

0:38:42.280 --> 0:38:43.920
<v Speaker 1>that that was the case. Let us know if you

0:38:44.000 --> 0:38:46.160
<v Speaker 1>like bats or if you you know, you think we're

0:38:46.200 --> 0:38:51.680
<v Speaker 1>totally wrong here and you're like, all bats must be annihilated. Right. Also,

0:38:51.920 --> 0:38:55.680
<v Speaker 1>look to Facebook because we're probably going to be doing

0:38:55.719 --> 0:38:59.560
<v Speaker 1>a Facebook live about I would imagine Demons and Bats

0:38:59.640 --> 0:39:03.200
<v Speaker 1>that week that these episodes come out related to trailers

0:39:03.239 --> 0:39:05.200
<v Speaker 1>of movies that have bats in them. Do you remember

0:39:05.239 --> 0:39:08.400
<v Speaker 1>that bat movie that had Um Lou Diamond Phillips in it,

0:39:08.560 --> 0:39:11.640
<v Speaker 1>who was literally called just bats. No, I don't think

0:39:11.719 --> 0:39:13.239
<v Speaker 1>remember that came out in the nineties. It was a

0:39:13.239 --> 0:39:15.160
<v Speaker 1>pretty terrible horror movie. We might have to pull that

0:39:15.200 --> 0:39:17.360
<v Speaker 1>one out, man. I can think of at least a

0:39:17.360 --> 0:39:19.479
<v Speaker 1>couple of that related to our films for the Path.

0:39:19.840 --> 0:39:22.319
<v Speaker 1>It would be fun to discuss. I think. I think

0:39:22.320 --> 0:39:24.480
<v Speaker 1>we've got a good trailer talk coming up for us.

0:39:24.520 --> 0:39:26.520
<v Speaker 1>So if you like watching those, or if you've never

0:39:26.520 --> 0:39:28.920
<v Speaker 1>seen one before, tune in on Facebook. You don't have

0:39:28.960 --> 0:39:30.560
<v Speaker 1>to watch it when it's live. It'll sit on our

0:39:30.600 --> 0:39:33.840
<v Speaker 1>Facebook page. Usually Robert, Joe and I sitting around for

0:39:33.840 --> 0:39:36.880
<v Speaker 1>about thirty minutes talking about the science related to this

0:39:36.920 --> 0:39:42.160
<v Speaker 1>week's episodes, tying into our favorite monster movie trailers, so

0:39:42.440 --> 0:39:44.200
<v Speaker 1>you can find that on our Facebook page. You can

0:39:44.239 --> 0:39:47.160
<v Speaker 1>also contact us through Facebook. We're also on Twitter, We're

0:39:47.160 --> 0:39:49.840
<v Speaker 1>on tumbler, We're on Instagram. We've also got stuff to

0:39:49.840 --> 0:39:52.920
<v Speaker 1>blow your Mind dot com, where there's all those bat

0:39:52.920 --> 0:39:55.440
<v Speaker 1>podcasts that Julie and Robert did in the past. If

0:39:55.480 --> 0:39:58.400
<v Speaker 1>you want to just binge listen to bad information, we

0:39:58.520 --> 0:40:00.279
<v Speaker 1>got it. And if you want to get touch with

0:40:00.400 --> 0:40:03.000
<v Speaker 1>us the old fashioned way, just hit us up at

0:40:03.120 --> 0:40:14.960
<v Speaker 1>blow the Mind at house stuff works dot com for

0:40:15.120 --> 0:40:17.400
<v Speaker 1>more on this and thousands of other topics. Is it

0:40:17.480 --> 0:40:41.360
<v Speaker 1>how stuff works dot com