WEBVTT - The Psychedelic Nightmare of Ergotism

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<v Speaker 1>Welcome to Stuff to Blow your Mind from how Stuff

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<v Speaker 1>Works dot com. Hey, welcome to stuff to Blow your Mind.

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<v Speaker 1>My name is Robert Lamb and I'm Joe McCormick. Joe listeners.

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<v Speaker 1>Imagine yourself a time traveling wonderer in the sixteenth Citree.

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<v Speaker 1>It's a time of horror and wonder, of budding possibilities

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<v Speaker 1>for a more informed age, as well uh as pools

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<v Speaker 1>of lingering shadow and superstition. You come to the Monastery

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<v Speaker 1>of Saint Anthony in Eisenheim, near Colmar and what is

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<v Speaker 1>now modern day France. Now what do you expect to find?

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<v Speaker 1>It's such a monastery. How is your education and entertainment

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<v Speaker 1>prepared you for such a place? Pious robed brothers praying

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<v Speaker 1>before elaborate altars, studious monks secluded in their libraries and

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<v Speaker 1>scriptoriums ah. But here you encounter the stinch of illness

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<v Speaker 1>and corruption. You hear the cries of the pain than

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<v Speaker 1>the mad. You find the hospital brothers of Saint Anthony

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<v Speaker 1>as they tirelessly treat victims of plague, skin disease, and

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<v Speaker 1>especially that condition known as Saint Anthony's fire or urgic poisoning.

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<v Speaker 1>As you make your way through the monastery, you glimpse

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<v Speaker 1>of blackened limbs, you hear psychotic cries, voices describing hallucination

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<v Speaker 1>straight from some surrealistic vision of hell, and as you

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<v Speaker 1>enter the sanctuary yourself, you glimpse and altar unlike anything

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<v Speaker 1>you've imagined before. Behold the Eisenheim altarpiece of Matthias Grunwald

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<v Speaker 1>in its current configuration. The great folding work of art

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<v Speaker 1>presents a familiar motif, Jesus Christ crucified at Golgotha, but

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<v Speaker 1>it's easily the most grotesque image of Christ you've ever seen.

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<v Speaker 1>You'd be tempted to think it blasphemous, even for Christ's

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<v Speaker 1>skin is dark at times, greenish, gangrenous, covered in sores

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<v Speaker 1>in addition to the familiar wounds of execution. Because this

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<v Speaker 1>work of art, this interpretation of absolute human death and suffering,

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<v Speaker 1>emerges from the ravages of ergotism. Ergotism, so that's going

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<v Speaker 1>to be the subject today. But I've seen this work

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<v Speaker 1>of art you're talking about, You've called attention to it

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<v Speaker 1>before Gruenwald's Diseased Christ, and it looks like something that is,

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<v Speaker 1>as you pointed out, intended to be blasphemous. It looks

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<v Speaker 1>like something from a metal album insert. Like, you know,

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<v Speaker 1>you're flipping through the pages of the CD insert and

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<v Speaker 1>it's got a pentagram, and it's got like a you know,

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<v Speaker 1>crucified goat with blood everywhere, and then it's got this

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<v Speaker 1>diseased Jesus with with you know, sores and this greenish body.

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<v Speaker 1>It doesn't look like your traditional image of the of

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<v Speaker 1>pious Christ, right, Yeah, it's and it's it's fascinating and

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<v Speaker 1>it it is. When we get into it, you'll see

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<v Speaker 1>that it is a very pious image. It was not

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<v Speaker 1>created out of any sense of you know, blasphemous outrage,

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<v Speaker 1>but it does look like zombie Jesus. Yeah, So what

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<v Speaker 1>is Ergot And what in the world would something called

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<v Speaker 1>Ergot have to do with a diseased Christ from a

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<v Speaker 1>metal album insert? So imagine you're walking through a grain

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<v Speaker 1>field with tall stalks of rye all around you, and

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<v Speaker 1>so we're not all that close to the agriculture that

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<v Speaker 1>sustains our lives anymore. Rye might actually need some explanation.

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<v Speaker 1>It is a cultivated grass crops, so it's like wheat

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<v Speaker 1>or barley, and we can use rye to make bread's beer, whiskey.

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<v Speaker 1>The scientific name of this plant is secale cereal l A.

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<v Speaker 1>I think secale and then like cereal with any at

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<v Speaker 1>the end. So you're a body meeting a body coming

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<v Speaker 1>through the rye, and you notice that on some of

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<v Speaker 1>the stalks of the grass of the rye, where the

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<v Speaker 1>little rye grains would normally be poking out of the stalk,

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<v Speaker 1>there are instead these long, dark, purple to black fingers

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<v Speaker 1>reaching into the air like twisted, deformed little uh mockery's

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<v Speaker 1>of the seeds that should be in this plant. One

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<v Speaker 1>are these things? Well, each of these little fingers is

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<v Speaker 1>an ergot, or another name for them in science would

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<v Speaker 1>be the sclerotium. It's a piece of fungal tissue, so

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<v Speaker 1>it's mushroom in nature fungus, and it grows when the

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<v Speaker 1>grain is infected with the fungus Claviceps perpurea, and that's

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<v Speaker 1>a parasite that infects the ovaries, the female sex organs

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<v Speaker 1>of the plant. In grasses and the host is most

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<v Speaker 1>soften rye, but other grasses and grains can fall victim

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<v Speaker 1>to ergot. This is so common in rye that people

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<v Speaker 1>actually thought it was a part of the grain up

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<v Speaker 1>until the eighteen fifties when we really began to understand

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<v Speaker 1>the true fungal nature of the ergot, which is something

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<v Speaker 1>to keep in mind as we discussed the problems that

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<v Speaker 1>are mgered from human consumption of ergan. Exactly right. And

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<v Speaker 1>so we're gonna get to the human consumption in a minute,

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<v Speaker 1>because that's central to the podcast. But first we should

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<v Speaker 1>actually talk about what this thing is, what does it

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<v Speaker 1>due to the plants because nobody, nobody cares about the plants.

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<v Speaker 1>They're the ones that really suffer. So the urga itself,

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<v Speaker 1>what is this thing's little black, purple black finger poking

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<v Speaker 1>up out of the rye stalk. The urg it itself

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<v Speaker 1>is what's known as an overwintering structure. It so it's

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<v Speaker 1>this protective architecture that allows the fungus to survive through

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<v Speaker 1>the freezing season and make it to the next stage

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<v Speaker 1>in its reproductive cycle. Uh and clavisups produces both sexual

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<v Speaker 1>and asexual spores to spread and infect new hosts. When

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<v Speaker 1>the fungal infection cycle begins, you'll often see do forming

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<v Speaker 1>on the ovaries of the host plants. You know where

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<v Speaker 1>where the seed and grain structure is, and this sticky

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<v Speaker 1>residue is a mixture of the plant's own sap and

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<v Speaker 1>then a sexually produced fungal spores called canidia. And these

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<v Speaker 1>a sexual spores can in effect other hosts when they're

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<v Speaker 1>spread by physical contact, so on the bodies of insects,

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<v Speaker 1>or even by the splashes of rain drops. I don't

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<v Speaker 1>know if you've seen anything about how some parasites spread

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<v Speaker 1>from plant to plant by the rain. And the rain

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<v Speaker 1>hits the plant, it splashes the parasite everywhere onto the

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<v Speaker 1>plants next to it, So that's one method of transmission.

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<v Speaker 1>But then as the seed head matures, some of it's

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<v Speaker 1>normally healthy grains are replaced by these ergo it's or sclerotia,

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<v Speaker 1>which are designed to keep the fungal parasite alive through

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<v Speaker 1>the cold months. When the spring arrives, the surviving ergot

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<v Speaker 1>sprout multiple stromata, which are these stalks with little knobs

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<v Speaker 1>at the end, and they look more like what you

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<v Speaker 1>think of when you hear the word mushroom. There the

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<v Speaker 1>stromata singular stroma produced sexual spores as opposed to the

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<v Speaker 1>a sexual spores produced at the earlier stage called asco spores,

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<v Speaker 1>and once the spores are developed, they get spit out

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<v Speaker 1>into the air to carry on the circle of life

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<v Speaker 1>of fungus, and so, like wind driven pollen, they get

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<v Speaker 1>caught in the stigma of other host plants and go

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<v Speaker 1>on to infect new grass ovaries. So that's the story

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<v Speaker 1>of Claviceps purpurea. It's not trying to get into you.

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<v Speaker 1>It's trying to get into the rye. It wants to

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<v Speaker 1>spread from plant to plant like a plague upon the

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<v Speaker 1>earth and become the zombie virus that that is the

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<v Speaker 1>rye apocalypse. But that is not actually the end of

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<v Speaker 1>the story. Because let's say we're back walking through this

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<v Speaker 1>field of infected rye, and instead of just walking through

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<v Speaker 1>the field, you're walking through the field with a scythe

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<v Speaker 1>and you're harvesting these ergan infested stalks, fungus fingers and all,

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<v Speaker 1>and you take it home and you turn it into

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<v Speaker 1>some delicious rye bread for you and your family to eat,

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<v Speaker 1>pastrami sandwiches. On what's going to happen to you? Well,

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<v Speaker 1>some bad stuff can happen um And in this we

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<v Speaker 1>get into sort of the complexities of of ergotism and

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<v Speaker 1>ergot poisoning, because we have essentially two different forms of

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<v Speaker 1>ergotism that can occur. Yeah, so in these overwintering structures. Uh,

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<v Speaker 1>these little black fingers, they're toxic alkaloids and they can

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<v Speaker 1>have various types of effects. Right, Yeah, there are essentially

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<v Speaker 1>there are different strains of the of the organism that

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<v Speaker 1>have different effects when consumed. So on one hand you

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<v Speaker 1>have gangrenous ergotism, which is as horrible as it sounds.

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<v Speaker 1>So the idea here is that ergotism is essentially a

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<v Speaker 1>vase of constrictor, so it constricts the blood vessels, so

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<v Speaker 1>it can severely limit the blood flow to the extremities,

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<v Speaker 1>which can result in a range of symptoms. Um, you

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<v Speaker 1>can get nausea, limb pain and this, Uh, this particular

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<v Speaker 1>pain in the limbs is often described as having a

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<v Speaker 1>burning sensation, which earned it the nickname ignis say holy

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<v Speaker 1>fire and this and it can also cause the skin

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<v Speaker 1>to appeal. Blisters to you occur all over and then

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<v Speaker 1>this can essentially even lead to to to gang green

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<v Speaker 1>occurring because again the blood vessels are constricted, it's less

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<v Speaker 1>blood reaching the extremities, and these extremities can then turn

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<v Speaker 1>black and mummified, causing the infected limbs to spontaneously break

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<v Speaker 1>off at the joints. But there's no pain involved in

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<v Speaker 1>this because it's just been cut off, so it's already dead. Yeah,

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<v Speaker 1>it's just dead tissue at this point, but it's still rotting.

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<v Speaker 1>It's still that the stinch can still be just completely unbearable. Yeah,

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<v Speaker 1>so just imagine that, because you ate the regular food

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<v Speaker 1>from your regular food supply coming in maybe through your

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<v Speaker 1>town bakery or something like that, you end up with

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<v Speaker 1>mummified feet or mummified hands and you're still alive, but

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<v Speaker 1>you've got blackened limbs that burn it first, then turn

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<v Speaker 1>black like a mummy and fall off. Yeah. It's what

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<v Speaker 1>kind of surreal life is this? It's terrifying, especially when

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<v Speaker 1>you think about it coming from consuming because we so

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<v Speaker 1>often don't think of bread as being this dangerous thing

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<v Speaker 1>because it's such an artificial food substance, right, right, it's

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<v Speaker 1>not like maynnai is left out in the sun that

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<v Speaker 1>you can just you know, we quickly think of as

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<v Speaker 1>like that's going to be a problem in your body, Right,

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<v Speaker 1>it's bread, what could go wrong? Okay, So that's gangernous sarchetism.

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<v Speaker 1>But then there's also convulsive evergotism, and this is the

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<v Speaker 1>nervous dysfunction variant UH, and this can also result in

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<v Speaker 1>a host of horrible things such as vomiting, diarrhea, lethargy,

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<v Speaker 1>the sensation of ants and spiders crawling all over your body,

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<v Speaker 1>what painful seizures, twitching, spasms, convulsions, blindness, deafness, um and

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<v Speaker 1>generally that the gastro intestinal symptoms that I mentioned. Those

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<v Speaker 1>proceed a full blown central nervous system condition, and in

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<v Speaker 1>its in extremes, you're also encountering hallucinations, mania and psychosis.

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<v Speaker 1>Can you get both strains at the same time? Oh? Yes,

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<v Speaker 1>that's where it gets even because I'm one, hay. Do

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<v Speaker 1>you have the mummified stinking flesh rotting variant, then you

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<v Speaker 1>have the madness, spiders all over me, and I'm in

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<v Speaker 1>just a psychotic collusiontory state. And indeed, um they can

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<v Speaker 1>occur concurrently, so you can get a mixed form. Though

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<v Speaker 1>historically we tend to see geographic areas in Europe with

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<v Speaker 1>greater tendency towards one form of the these versus the other,

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<v Speaker 1>because again we're looking at slightly different strains of the

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<v Speaker 1>fungus causing either a convulsive organginous organism. And then there's

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<v Speaker 1>Also this the ergic stage of the fungus contains a

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<v Speaker 1>storehouse of various compounds, ranging from the benign to even

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<v Speaker 1>as well discussed beneficial uh. And since the proportions of

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<v Speaker 1>the compound vary even within the species, the same person

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<v Speaker 1>might experience different symptoms on a subsequent consumption of the

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<v Speaker 1>same ergic strain. So you're just kind of rolling the

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<v Speaker 1>like awful dungeon master dice every time you come across

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<v Speaker 1>some erg it in your bread. That's so scary. And

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<v Speaker 1>also just combine this with the fact that it was

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<v Speaker 1>so common in the medieval period, and you can just

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<v Speaker 1>imagine the confusion and the terror that went along with

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<v Speaker 1>all of this suffering. Yeah, because you have in areas

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<v Speaker 1>where there is a big dependency on rye bread for food,

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<v Speaker 1>and so you're gonna have Also, you have areas where

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<v Speaker 1>like one baker may be providing the entire town's bread.

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<v Speaker 1>So you have cases where entire medieval towns suffered from

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<v Speaker 1>this um. I mean, it was it was an epidemic. Um.

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<v Speaker 1>On top of that, it tended to target the poorer

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<v Speaker 1>um portions of the population because the dirty your grain,

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<v Speaker 1>the less choice you have in your your grain source

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<v Speaker 1>and your bread. Uh, the more likely you are to

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<v Speaker 1>to encounter urgotism. Well, you know, that made me wonder,

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<v Speaker 1>actually how long ergotism has been a problem for grass

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<v Speaker 1>eating animals on Earth. Because one of the things that

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<v Speaker 1>is certainly true is it's not just humans that get it.

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<v Speaker 1>I mean, people don't just get it from rye cereals

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<v Speaker 1>and rye bread and stuff. Animals get it. Livestock can

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<v Speaker 1>suffer from gangrenous ergitism just from eating infected grasses and grains.

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<v Speaker 1>And apparently this might go back a really long time.

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<v Speaker 1>I was wondering just how long his old clavicep has

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<v Speaker 1>been attacking hungry grass eaters with its overwintering structures. Well,

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<v Speaker 1>we know the existence of ergot is tied to the

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<v Speaker 1>existence of its host, which is grass, And until recently,

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<v Speaker 1>we actually didn't know exactly how old grass was. I

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<v Speaker 1>thought that was kind of weird, but that was true.

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<v Speaker 1>We didn't know exactly how far back this plant went.

0:13:40.040 --> 0:13:43.840
<v Speaker 1>According to a report in the journal Paleo Diversity, a

0:13:44.000 --> 0:13:48.400
<v Speaker 1>chunk of amber from Mayan Mark contains a preserved sample

0:13:48.640 --> 0:13:53.880
<v Speaker 1>of fungus structure very similar to ergat atop a grass spikelet.

0:13:53.960 --> 0:13:56.320
<v Speaker 1>That's a structure at the top of the grass. You

0:13:56.360 --> 0:13:59.120
<v Speaker 1>know that we uh where the argot would be manifest

0:14:00.040 --> 0:14:04.480
<v Speaker 1>and this positions urget fungus around a hundred million years old,

0:14:05.880 --> 0:14:11.679
<v Speaker 1>so well within the Cretaceous period, which means dinosaurs. Okay,

0:14:11.720 --> 0:14:15.600
<v Speaker 1>so we don't know exactly if dinosaurs ate this stuff,

0:14:16.440 --> 0:14:19.200
<v Speaker 1>and we don't know exactly what effect this stuff would

0:14:19.200 --> 0:14:21.280
<v Speaker 1>have had on dinosaurs who ate it if they did

0:14:21.360 --> 0:14:24.640
<v Speaker 1>eat it, but if they reacted anything like the mammals

0:14:24.680 --> 0:14:27.800
<v Speaker 1>who eat it, that leads us to imagine a bizarre

0:14:27.960 --> 0:14:33.960
<v Speaker 1>landscape of Cretaceous herbivores like triceratops at twenty thou pounds

0:14:33.960 --> 0:14:39.600
<v Speaker 1>having nightmarish hallucinations and doing the st Vitus dance. Wow,

0:14:39.640 --> 0:14:42.960
<v Speaker 1>I mean, I shouldn't laugh, poor poor creature. But but

0:14:43.040 --> 0:14:45.160
<v Speaker 1>at the same time, you have to imagine this uh,

0:14:45.280 --> 0:14:48.600
<v Speaker 1>this psychotic substance that we uh. We end up focusing

0:14:48.600 --> 0:14:51.400
<v Speaker 1>a lot on how it affects the human mind and

0:14:51.720 --> 0:14:54.280
<v Speaker 1>perception of self and even our religion. But to imagine

0:14:54.520 --> 0:14:58.720
<v Speaker 1>a dinosaur, or encountering at a dinosaur essentially uh engaging

0:14:58.760 --> 0:15:03.640
<v Speaker 1>in a dangerous um psychedelic substance, It's ah, it's pretty

0:15:03.680 --> 0:15:06.480
<v Speaker 1>mind blowing, mind blowing. Would be a word for it. Now.

0:15:06.600 --> 0:15:10.040
<v Speaker 1>Of course, the human relationship with ergotism also seems to

0:15:10.040 --> 0:15:13.520
<v Speaker 1>go back very far. Oh yeah, it gets it gets

0:15:13.520 --> 0:15:16.720
<v Speaker 1>interesting because you know, you also deal with the situations where,

0:15:16.720 --> 0:15:19.080
<v Speaker 1>all right, if it is every it's only going to

0:15:19.160 --> 0:15:23.400
<v Speaker 1>show up in places where you actually have civilizations consuming

0:15:23.440 --> 0:15:27.040
<v Speaker 1>a lot of rye Um. There are Assyrian tablets from

0:15:27.080 --> 0:15:30.560
<v Speaker 1>around the six hundred BC that speak of a quote

0:15:30.640 --> 0:15:35.480
<v Speaker 1>noxious pustule in the ear of grain. There um. We

0:15:35.560 --> 0:15:41.280
<v Speaker 1>also see South Asian zoroastron texts that right of quote

0:15:41.440 --> 0:15:44.240
<v Speaker 1>grasses that cause pregnant women to drop the womb and

0:15:44.280 --> 0:15:47.520
<v Speaker 1>die in childbirth, and those are from around four hundred

0:15:47.560 --> 0:15:50.760
<v Speaker 1>BC to three hundred BC. But then, you know, we

0:15:50.800 --> 0:15:52.960
<v Speaker 1>turned to the Greeks and Romans, who we often depend

0:15:53.040 --> 0:15:55.760
<v Speaker 1>on for, you know, accounts of of happenings in the

0:15:55.760 --> 0:15:58.520
<v Speaker 1>ancient world, and they were not big on rye bread,

0:15:58.720 --> 0:16:02.360
<v Speaker 1>so they make no mention of it um, which of

0:16:02.400 --> 0:16:04.840
<v Speaker 1>course really cuts into our ability to track it through

0:16:04.840 --> 0:16:09.000
<v Speaker 1>the ancient world. And yet the Greeks do, and this

0:16:09.080 --> 0:16:12.680
<v Speaker 1>is kind of arguable, but the Greeks do give us

0:16:12.760 --> 0:16:16.240
<v Speaker 1>the myth of the temple of el Usus, devoted to

0:16:16.280 --> 0:16:20.800
<v Speaker 1>the cult of Demeter and Persephone a literal descent into hell.

0:16:20.840 --> 0:16:25.800
<v Speaker 1>If you remember that story with Persephone abducted by Hades, etcetera.

0:16:26.160 --> 0:16:29.720
<v Speaker 1>On the temple is a literal descent into hell. No, no, no,

0:16:29.840 --> 0:16:33.560
<v Speaker 1>that the myth is a little exactly yeah. Um, but

0:16:33.560 --> 0:16:37.640
<v Speaker 1>but they're they're concerned with with this story. Uh, the

0:16:37.680 --> 0:16:41.040
<v Speaker 1>myth of the Temple's right. Yeah, so not to to

0:16:41.280 --> 0:16:44.280
<v Speaker 1>rehatch the whole story, but of course it involves essentially

0:16:44.280 --> 0:16:48.720
<v Speaker 1>springtime and summer being kidnapped by Hades and the inevitable

0:16:48.800 --> 0:16:52.040
<v Speaker 1>cycles of seasons that of course ties into agriculture. And

0:16:52.080 --> 0:16:55.040
<v Speaker 1>this is an old agrarian cult. And in order to

0:16:55.200 --> 0:16:57.840
<v Speaker 1>enter this temple, you had to fast, you had to rest,

0:16:57.840 --> 0:17:00.640
<v Speaker 1>you had to make sacrifices, and you also drank something

0:17:00.680 --> 0:17:06.400
<v Speaker 1>called kai kion, which is a strange purple potion. Um.

0:17:06.480 --> 0:17:12.240
<v Speaker 1>And again think of clouds proparia resulting in tears, hallucinations, tremors,

0:17:12.240 --> 0:17:16.040
<v Speaker 1>and sweats and so some suggest that this might have

0:17:16.119 --> 0:17:20.600
<v Speaker 1>been derived from cloud steps proparia. And uh and who

0:17:20.640 --> 0:17:24.000
<v Speaker 1>better than an ancient agrarian cult to utilize the reality

0:17:24.040 --> 0:17:26.919
<v Speaker 1>warping powers of a crop fucus? Right, Yeah, this points

0:17:26.920 --> 0:17:30.080
<v Speaker 1>out one thing that's especially scary. I think I couldn't

0:17:30.160 --> 0:17:31.960
<v Speaker 1>quite put my finger on what it was earlier in

0:17:32.000 --> 0:17:35.400
<v Speaker 1>this episode, but the way in which agriculture is so

0:17:35.520 --> 0:17:40.080
<v Speaker 1>deeply tied to civilization, Like in some ways, agriculture is

0:17:40.240 --> 0:17:43.520
<v Speaker 1>sort of the definition of civilization. When do civilization arise,

0:17:43.600 --> 0:17:46.280
<v Speaker 1>it's when we settle down and grow crops, and what

0:17:46.359 --> 0:17:50.040
<v Speaker 1>are our main crops their grains. Then also there is

0:17:50.080 --> 0:17:53.840
<v Speaker 1>the fact that much like you're pointing out here, many

0:17:53.920 --> 0:17:57.720
<v Speaker 1>of the world's religions, and especially many ancient religions, have

0:17:58.040 --> 0:18:02.119
<v Speaker 1>deeply agricultural themes that are based on grains. That you know,

0:18:02.200 --> 0:18:05.760
<v Speaker 1>there are death and rebirth cycles of the gods and

0:18:05.840 --> 0:18:08.480
<v Speaker 1>of the ancient heroes that are based on the cycles

0:18:08.520 --> 0:18:11.760
<v Speaker 1>of seasons, the growth of crops in the harvest. Yeah, indeed,

0:18:11.800 --> 0:18:14.159
<v Speaker 1>I mean you see that transition from the old gods

0:18:14.160 --> 0:18:16.560
<v Speaker 1>of the hunt, the chaotic gods of the hunt. I

0:18:16.560 --> 0:18:18.879
<v Speaker 1>don't know what my next meal is going to reach me.

0:18:18.920 --> 0:18:21.160
<v Speaker 1>It depends entirely on what kind of animal I can kill,

0:18:21.359 --> 0:18:24.800
<v Speaker 1>to this more dependable, cyclical nature in the very the

0:18:24.840 --> 0:18:27.480
<v Speaker 1>grarian gods that go with it. Yeah, So it's obvious

0:18:27.560 --> 0:18:30.320
<v Speaker 1>that over time the notion of agriculture has been deeply

0:18:30.520 --> 0:18:35.239
<v Speaker 1>ingrained in us, like pun not intended, deeply sort of

0:18:35.320 --> 0:18:39.080
<v Speaker 1>injected into our minds and and into our cultures, so

0:18:39.119 --> 0:18:43.479
<v Speaker 1>that it even shows up in our mythological and magical symbols.

0:18:43.520 --> 0:18:46.840
<v Speaker 1>So the idea that our grain can be corrupted in

0:18:46.880 --> 0:18:50.359
<v Speaker 1>a way that that makes us sea hell, you know,

0:18:50.480 --> 0:18:53.760
<v Speaker 1>and feel burning in our bodies is so is so

0:18:53.880 --> 0:18:59.240
<v Speaker 1>perverse and unpleasant and disruptive of what society should be,

0:18:59.440 --> 0:19:03.400
<v Speaker 1>which is safty instability. Yeah, of course, during the fact

0:19:03.480 --> 0:19:06.000
<v Speaker 1>that agriculture itself is kind of a perversion of a

0:19:06.119 --> 0:19:08.760
<v Speaker 1>natural process for our benefit. Yeah, that's a good point.

0:19:09.080 --> 0:19:12.959
<v Speaker 1>So anyway, it's not until the Christian era that urgantism

0:19:13.040 --> 0:19:16.600
<v Speaker 1>is actually described in surviving accounts. Again, uh, and this

0:19:16.680 --> 0:19:19.359
<v Speaker 1>is around the time when rise introduced into Western Europe.

0:19:19.640 --> 0:19:23.080
<v Speaker 1>So are very early outbreaks of urgotism. We see them

0:19:23.119 --> 0:19:26.280
<v Speaker 1>documented in the Rhine Valley in the year eight fifty seven.

0:19:27.080 --> 0:19:29.840
<v Speaker 1>And again it disproportionately affects the poor, who had less

0:19:29.920 --> 0:19:32.960
<v Speaker 1>choice about you know, their grain sources and their how

0:19:33.000 --> 0:19:37.160
<v Speaker 1>dirty their grain is. Um and urg It was most

0:19:37.400 --> 0:19:40.439
<v Speaker 1>common when a harsh winter followed a cool, wet spring,

0:19:40.600 --> 0:19:43.560
<v Speaker 1>because many would exhaust their food supplies and they'd be

0:19:43.640 --> 0:19:46.320
<v Speaker 1>forced to eat the infected grain. Okay, so they knew

0:19:46.400 --> 0:19:49.840
<v Speaker 1>something might not be great about the grain that had

0:19:49.920 --> 0:19:52.000
<v Speaker 1>lots of erg it in it. Yeah, just the the

0:19:52.080 --> 0:19:54.800
<v Speaker 1>dirtier grain. Yeah, there was. They weren't able to like

0:19:54.840 --> 0:19:57.359
<v Speaker 1>completely put everything together, but there were there was some

0:19:57.480 --> 0:20:00.880
<v Speaker 1>ideas about it. Um. And then from around nine hundred

0:20:01.040 --> 0:20:05.600
<v Speaker 1>uh ce when records uh evidently became more common in

0:20:05.640 --> 0:20:08.520
<v Speaker 1>what is now France and Germany, to around uh hundred,

0:20:08.600 --> 0:20:12.840
<v Speaker 1>see you see severe epidemics of urgotism affecting large areas

0:20:12.880 --> 0:20:17.000
<v Speaker 1>every five to ten years. Yeah, and of course it

0:20:17.080 --> 0:20:20.439
<v Speaker 1>becomes such an issue that in ten ninety three you

0:20:20.480 --> 0:20:23.119
<v Speaker 1>see the founding of a religious order, the Order of

0:20:23.359 --> 0:20:26.840
<v Speaker 1>hospital Ers of Saint Anthony, founded in southern France to

0:20:26.960 --> 0:20:30.199
<v Speaker 1>help those afflicted. Uh. Saint Anthony is of course the

0:20:30.240 --> 0:20:33.359
<v Speaker 1>patron saint of skin diseases, and that the malady itself

0:20:33.400 --> 0:20:37.080
<v Speaker 1>was named Saint Anthony's Fire. Uh. Anthony of course is

0:20:37.080 --> 0:20:41.720
<v Speaker 1>said to face supernatural temptations kind of hallucinatory U encounters.

0:20:41.760 --> 0:20:44.680
<v Speaker 1>So this is of course a favorite subject in Western

0:20:44.800 --> 0:20:47.960
<v Speaker 1>art from the medieval period onward, which makes him even

0:20:47.960 --> 0:20:51.200
<v Speaker 1>more suitable for this so the monks built over three

0:20:51.240 --> 0:20:55.919
<v Speaker 1>hundred seventy hospitals, and those who came often found some

0:20:56.000 --> 0:20:59.640
<v Speaker 1>relief from urgotism. Uh, though it's kind of you can

0:20:59.800 --> 0:21:01.359
<v Speaker 1>kind to get into the situation. How much of it

0:21:01.400 --> 0:21:04.040
<v Speaker 1>is they're treating of the skin ailments, and they also

0:21:04.040 --> 0:21:07.680
<v Speaker 1>treated other skin ailments beside or beside organism. But then

0:21:07.720 --> 0:21:10.720
<v Speaker 1>also while you're under their care, you're probably not continuing

0:21:10.760 --> 0:21:14.920
<v Speaker 1>to consume that rye bread while you're under the care

0:21:14.920 --> 0:21:18.800
<v Speaker 1>of the hospitalers, so that can contribute to your recovery.

0:21:19.359 --> 0:21:23.280
<v Speaker 1>Then you go back home and you're back restarted. Yet

0:21:23.320 --> 0:21:25.520
<v Speaker 1>another reason. It seems like we're all rather fortunate we

0:21:25.560 --> 0:21:29.480
<v Speaker 1>don't live in medieval Europe. Um. And of course you

0:21:29.520 --> 0:21:32.320
<v Speaker 1>have other things that are occurring of probably due to

0:21:32.440 --> 0:21:34.920
<v Speaker 1>organism as well as all of our Sacks points out

0:21:34.920 --> 0:21:38.600
<v Speaker 1>in his excellent book Hallucinations. Uh. Some historians attribute organ

0:21:38.680 --> 0:21:41.840
<v Speaker 1>poisoning as a possible factor much later, with the Salem

0:21:42.040 --> 0:21:44.880
<v Speaker 1>witch hysteria in the New World, but it may also

0:21:44.960 --> 0:21:48.359
<v Speaker 1>explain the dancing plagues reported between the fourteenth and seventeenth

0:21:48.359 --> 0:21:54.040
<v Speaker 1>century as well. So individuals suddenly behaving erratically in mass Uh.

0:21:54.119 --> 0:21:56.480
<v Speaker 1>You get into arguments, is this mass hysteria. Is this

0:21:56.560 --> 0:22:01.159
<v Speaker 1>more of a you know, a social contagion, or is

0:22:01.160 --> 0:22:04.720
<v Speaker 1>it indeed tied to the consumption of ergot and and

0:22:04.720 --> 0:22:07.680
<v Speaker 1>and and suffering from convulsive ergotism. Yeah, and obviously we

0:22:07.960 --> 0:22:09.960
<v Speaker 1>don't have the answer there. I think a lot of

0:22:09.960 --> 0:22:12.600
<v Speaker 1>people are skeptical of the idea that ergot caused the

0:22:12.680 --> 0:22:15.240
<v Speaker 1>dancing manias. If you're not familiar, you should look these

0:22:15.320 --> 0:22:18.080
<v Speaker 1>up there. They're crazy, the the ideas that you know,

0:22:18.160 --> 0:22:21.200
<v Speaker 1>in random places throughout Europe in the medieval period, you'd

0:22:21.200 --> 0:22:25.320
<v Speaker 1>have suddenly lots of people would just start dancing and

0:22:25.520 --> 0:22:29.040
<v Speaker 1>it seemed they seemed possessed in some way like that

0:22:29.160 --> 0:22:32.639
<v Speaker 1>they couldn't stop, and people were afraid they didn't know

0:22:32.680 --> 0:22:36.119
<v Speaker 1>what was going on. And now, I mean, I don't

0:22:36.119 --> 0:22:39.040
<v Speaker 1>really see phenomenon like that occurring today, so I don't

0:22:39.080 --> 0:22:41.080
<v Speaker 1>even really know what I could compare it to. Well,

0:22:41.119 --> 0:22:45.040
<v Speaker 1>there you do see accounts of mass hysteria um and

0:22:45.560 --> 0:22:47.240
<v Speaker 1>we actually have an episode on this off the link

0:22:47.320 --> 0:22:49.879
<v Speaker 1>to on the the landing page of this episode. You

0:22:49.880 --> 0:22:51.960
<v Speaker 1>do see accounts where you'll say, I have a group

0:22:52.000 --> 0:22:56.560
<v Speaker 1>of school children at at at a academy somewhere, and

0:22:56.600 --> 0:22:59.120
<v Speaker 1>they all believe they'd come down with an illness when

0:22:59.119 --> 0:23:02.719
<v Speaker 1>there's actually no this that sort of thing. Um uh.

0:23:03.320 --> 0:23:07.119
<v Speaker 1>Also in the past, you know a few centuries accounts

0:23:07.119 --> 0:23:10.480
<v Speaker 1>of everyone in a particular area claiming to see some

0:23:10.520 --> 0:23:12.879
<v Speaker 1>sort of supernatural event, to all really see it or

0:23:12.920 --> 0:23:15.199
<v Speaker 1>is it just kind of this this group, you know,

0:23:15.240 --> 0:23:18.320
<v Speaker 1>this collective hysteria that's taking over them. Yeah, So the

0:23:18.359 --> 0:23:20.720
<v Speaker 1>general hypothesis is that it might have had something to

0:23:20.800 --> 0:23:22.560
<v Speaker 1>do with some of these dancing manias. We don't know.

0:23:22.720 --> 0:23:25.520
<v Speaker 1>But the specific one about the Salem which trials is interesting.

0:23:26.240 --> 0:23:30.040
<v Speaker 1>How exactly does the does the ergot theory come in here? Yes,

0:23:30.119 --> 0:23:34.080
<v Speaker 1>some historians feel that it's entirely possible that Elizabeth Paris,

0:23:34.119 --> 0:23:36.959
<v Speaker 1>the first girl to to fall ill, actually suffered from

0:23:37.000 --> 0:23:39.119
<v Speaker 1>some sort of ergot poisoning and then the rest of

0:23:39.119 --> 0:23:42.920
<v Speaker 1>the girls um took the opportunity to stave off their

0:23:42.960 --> 0:23:46.639
<v Speaker 1>boredom uh and and engage in this kind of persecution.

0:23:46.680 --> 0:23:49.840
<v Speaker 1>It it kind of drives home like the problem of

0:23:49.840 --> 0:23:52.120
<v Speaker 1>pointing out any kind of strange occurrence in the past

0:23:52.160 --> 0:23:54.119
<v Speaker 1>and saying, oh, well, this was this poisoning, or this

0:23:54.200 --> 0:23:57.040
<v Speaker 1>was a psychedelic or or what have you, because ultimately

0:23:57.040 --> 0:24:01.040
<v Speaker 1>the social dynamics of these situations are airly complex and

0:24:01.080 --> 0:24:04.120
<v Speaker 1>there can be multiple energies feeding into them. Yeah. Yeah,

0:24:04.160 --> 0:24:06.760
<v Speaker 1>psychohistory is a very difficult thing to try to do.

0:24:06.840 --> 0:24:09.240
<v Speaker 1>Didn't Josh Clark write something about this for the website?

0:24:09.280 --> 0:24:12.480
<v Speaker 1>He did? He wrote where the American Colonists drugged during

0:24:12.480 --> 0:24:15.920
<v Speaker 1>the Salem Witch Trials? And in it he he points

0:24:16.000 --> 0:24:18.919
<v Speaker 1>out that, you know, one of the criticisms with some

0:24:18.960 --> 0:24:22.200
<v Speaker 1>of these the theories, uh, you know, raises the question

0:24:22.880 --> 0:24:25.440
<v Speaker 1>why only the girls, why not the others? Why only

0:24:25.520 --> 0:24:28.680
<v Speaker 1>six two? Why not previous years? In later years? So

0:24:29.400 --> 0:24:32.600
<v Speaker 1>when you start trying to say, you know, say urgantism

0:24:32.680 --> 0:24:36.439
<v Speaker 1>is the is the smoking gun here? Uh, there's just

0:24:36.480 --> 0:24:41.920
<v Speaker 1>so many additional questions that arise, like bread, like bread,

0:24:42.240 --> 0:24:46.040
<v Speaker 1>just to make sure we get another vacant well, terrible puns.

0:24:46.080 --> 0:24:48.000
<v Speaker 1>But I mean whether or not it had any role

0:24:48.040 --> 0:24:50.560
<v Speaker 1>to play in dancing manias or the Salem witch Trials,

0:24:50.560 --> 0:24:55.440
<v Speaker 1>it certainly was a real phenomenon that was psychedelic and horrifying. Yeah. Now,

0:24:55.640 --> 0:24:57.639
<v Speaker 1>we mentioned that by the eighteen fifties we had a

0:24:57.680 --> 0:25:02.520
<v Speaker 1>pretty good understanding of how archetism were the last reported outbreak,

0:25:02.560 --> 0:25:05.120
<v Speaker 1>and this is by no means conclusive. There are alternative

0:25:05.280 --> 0:25:08.640
<v Speaker 1>theories for this as well. Um. The last reported outbreak

0:25:08.800 --> 0:25:12.040
<v Speaker 1>occurred in nineteen fifty one in pont Standard Spreit in

0:25:12.080 --> 0:25:15.640
<v Speaker 1>southern France, in which more than two cases were reported

0:25:15.680 --> 0:25:19.119
<v Speaker 1>along with four deaths. But again that's not cut and

0:25:19.200 --> 0:25:24.400
<v Speaker 1>dry either. So we mentioned the various compounds that are

0:25:24.600 --> 0:25:28.119
<v Speaker 1>that are that are in the uh, the fungus, right,

0:25:28.160 --> 0:25:30.879
<v Speaker 1>they have these alkaloids in them that can cause terrible

0:25:30.880 --> 0:25:35.120
<v Speaker 1>symptoms and diseases. But they can actually be used or

0:25:35.280 --> 0:25:38.840
<v Speaker 1>maybe derivatives from them can be used for legitimate medical purposes,

0:25:38.880 --> 0:25:40.919
<v Speaker 1>can't they They can? Yeah, I mean it's it's kind

0:25:40.920 --> 0:25:42.920
<v Speaker 1>of one of the you know, underlying ideas that any

0:25:43.000 --> 0:25:46.840
<v Speaker 1>kind of particularly powerful substance produced by nature, uh, it

0:25:46.920 --> 0:25:52.320
<v Speaker 1>can be utilized efficiently if if properly managed. Yeah. One

0:25:52.359 --> 0:25:55.000
<v Speaker 1>of my favorite technology stories is how to use animal

0:25:55.080 --> 0:25:59.000
<v Speaker 1>venom in medicine, like using scorpion venom in medicine to

0:25:59.040 --> 0:26:02.240
<v Speaker 1>treat diseases. Yeah, I mean, we we we have numerous

0:26:02.960 --> 0:26:06.360
<v Speaker 1>cases where we can take something that is in nature, uh,

0:26:06.440 --> 0:26:08.240
<v Speaker 1>this deadly substance, then we can use it for our

0:26:08.240 --> 0:26:12.080
<v Speaker 1>own benefit in a medicine or say a spice of flavoring. Um.

0:26:12.119 --> 0:26:14.879
<v Speaker 1>You know what, what is a spicy pepper added to

0:26:14.960 --> 0:26:17.600
<v Speaker 1>your your taco salad? But for a fun way to

0:26:17.640 --> 0:26:21.240
<v Speaker 1>see something unusual. Yeah, exactly. So with there we get.

0:26:21.240 --> 0:26:25.080
<v Speaker 1>We have a few different compounds of note UM. There's ergonovine.

0:26:25.280 --> 0:26:28.640
<v Speaker 1>This is a compound produced by clavisups Papyria that we've

0:26:28.720 --> 0:26:32.600
<v Speaker 1>used for centuries and even today to um to speed

0:26:32.680 --> 0:26:37.320
<v Speaker 1>up labor prevent postpartum bleeding. And we see it uh

0:26:37.480 --> 0:26:40.159
<v Speaker 1>we and in this we see the uh. The the

0:26:40.200 --> 0:26:44.520
<v Speaker 1>vaso constrictive properties of of er get put to good use,

0:26:44.560 --> 0:26:47.919
<v Speaker 1>and this is typically administered during the third stage of labor.

0:26:49.240 --> 0:26:53.520
<v Speaker 1>And then there's ERGOTAMINEU. This is useful with migraine headaches

0:26:53.520 --> 0:26:57.919
<v Speaker 1>because it reduces extra cranial blood flow. It's also a

0:26:57.960 --> 0:27:01.400
<v Speaker 1>serotonin agonist which can help alleviate the headaches as well.

0:27:02.440 --> 0:27:05.439
<v Speaker 1>And on top of that, they're scientists have looked into

0:27:05.440 --> 0:27:09.120
<v Speaker 1>the possibility that it could be used treating Parkinson's disease

0:27:09.680 --> 0:27:13.680
<v Speaker 1>since ergo is a dopamine agonist, meaning that it increases

0:27:13.720 --> 0:27:16.919
<v Speaker 1>the effects of the neurotransmitter dopamine in the brain UH.

0:27:17.000 --> 0:27:21.240
<v Speaker 1>In Parkinson's patients, dopamine transmitting neurons die off. So ergic

0:27:21.359 --> 0:27:25.040
<v Speaker 1>derivatives are helpful in boosting the signal between nerve cells

0:27:25.080 --> 0:27:27.840
<v Speaker 1>and the brain. And of course researchers can continue to

0:27:28.000 --> 0:27:32.160
<v Speaker 1>explore uses for compounds produced by the claviceps fungus as well.

0:27:33.200 --> 0:27:35.560
<v Speaker 1>That's right, I mean muscle relax here is potentially a

0:27:35.600 --> 0:27:39.680
<v Speaker 1>treatment of various circulatory diseases UM, and it might even

0:27:39.720 --> 0:27:42.320
<v Speaker 1>work as a possible anti tumor drugs. So you know,

0:27:42.359 --> 0:27:44.520
<v Speaker 1>the work continues. Again, it's a it's powerful substance, and

0:27:44.600 --> 0:27:47.159
<v Speaker 1>scientists continue to continue to come back to it and

0:27:47.200 --> 0:27:49.960
<v Speaker 1>look at possible uses for it. Right, But of course

0:27:50.080 --> 0:27:53.800
<v Speaker 1>we would be remiss if we did not discuss at

0:27:53.840 --> 0:28:01.000
<v Speaker 1>some length the relationship between ergot and psychedelic drugs. That's right, Um,

0:28:01.240 --> 0:28:04.359
<v Speaker 1>l s D in particular. Yeah, so urge actually plays

0:28:04.400 --> 0:28:07.920
<v Speaker 1>a role in the scientific isolation and discovery of L

0:28:08.040 --> 0:28:11.240
<v Speaker 1>s D by the Swiss chemist Albert Hoffman. Right. So yeah,

0:28:11.280 --> 0:28:14.600
<v Speaker 1>Back in the nineteen thirties, researchers at the Rockville Institute

0:28:14.560 --> 0:28:18.480
<v Speaker 1>in New York isolated lesurgic acid from an ergic compound,

0:28:18.600 --> 0:28:22.480
<v Speaker 1>and the research was the basis for Albert Hoffman's work

0:28:22.920 --> 0:28:27.440
<v Speaker 1>at Sandas a pharmaceutical company. And uh, and so the

0:28:27.440 --> 0:28:31.840
<v Speaker 1>the roots of LSD, the the roots of of lesergic

0:28:31.880 --> 0:28:37.200
<v Speaker 1>acid lie in the isolation of the compound within it. Yeah,

0:28:37.240 --> 0:28:39.760
<v Speaker 1>so Albert Hoffman was actually the one in in the

0:28:39.840 --> 0:28:44.640
<v Speaker 1>late nineteen thirties to derive LSD twenty five lessergic acid

0:28:44.880 --> 0:28:48.360
<v Speaker 1>uh diethyla minde. And if we believe the story, it

0:28:48.400 --> 0:28:52.440
<v Speaker 1>was not originally created for the purpose of causing acid trips,

0:28:53.920 --> 0:28:57.240
<v Speaker 1>now that the pharmaceutical companies had other things in mind.

0:28:57.320 --> 0:28:59.800
<v Speaker 1>But but I believe the story is that Hoffman a

0:29:00.120 --> 0:29:03.840
<v Speaker 1>sedentally dosed himself with this while working with it in

0:29:03.880 --> 0:29:06.720
<v Speaker 1>the lab and began to feel weird. He began to

0:29:06.720 --> 0:29:11.040
<v Speaker 1>feel the effects of an LSD trip, and after experiencing

0:29:11.080 --> 0:29:13.560
<v Speaker 1>that once, he was like, oh, that was kind of interesting,

0:29:13.760 --> 0:29:18.560
<v Speaker 1>maybe worth doing some more research, And so he synthesized

0:29:18.560 --> 0:29:22.280
<v Speaker 1>a batch to test on himself, basically right. And so

0:29:22.320 --> 0:29:24.400
<v Speaker 1>I know, you know a number of people are probably wondering,

0:29:24.440 --> 0:29:26.360
<v Speaker 1>what does that mean. I can grow ergic, I can

0:29:26.360 --> 0:29:30.440
<v Speaker 1>cultivate ergic and uh and therefore create my own LSD.

0:29:30.600 --> 0:29:34.000
<v Speaker 1>Well disclaimer, we're not recommending you do this, no, not

0:29:34.080 --> 0:29:37.400
<v Speaker 1>at all. And uh, even if you would you wanted to,

0:29:37.480 --> 0:29:39.760
<v Speaker 1>I think you would probably stall out on this process.

0:29:39.800 --> 0:29:43.920
<v Speaker 1>But uh, according to the vaults of Rowind, which is

0:29:44.000 --> 0:29:48.200
<v Speaker 1>a nonprofit educational organization that provides information about psychoactive plants

0:29:48.240 --> 0:29:52.600
<v Speaker 1>and chemicals, Uh, it's easier to do this than depending

0:29:52.600 --> 0:29:56.520
<v Speaker 1>on morning Glory or Hawaiian baby wood rose for the

0:29:56.720 --> 0:29:59.760
<v Speaker 1>surgic acid amides that you need. Now, we're not gonna

0:29:59.800 --> 0:30:03.320
<v Speaker 1>walk you through the process because it's um it's a

0:30:03.360 --> 0:30:05.840
<v Speaker 1>long process. And and by the way, it includes the

0:30:05.840 --> 0:30:10.440
<v Speaker 1>recommendation quote avoid prolonged contact with the errogant compounds as

0:30:10.480 --> 0:30:13.640
<v Speaker 1>they are poisonous and can be fatal. But suffice to

0:30:13.640 --> 0:30:16.800
<v Speaker 1>say that involves a lot of sterile and chemically specific

0:30:16.880 --> 0:30:20.920
<v Speaker 1>handling of clavists purpruria as a first step in a

0:30:21.000 --> 0:30:25.600
<v Speaker 1>long road to synthesizing lsd YA. So in addition to

0:30:25.680 --> 0:30:29.560
<v Speaker 1>the disclaimer, it's probably gonna be difficult, difficult, and you

0:30:29.640 --> 0:30:33.600
<v Speaker 1>my poison yourself. So maybe just you know, go watch

0:30:33.880 --> 0:30:36.920
<v Speaker 1>Fear and Loathing in Las Vegas again instead. There you go. Yeah,

0:30:37.000 --> 0:30:40.400
<v Speaker 1>but I want to get back to that disease, Jesus, Oh, yes,

0:30:40.800 --> 0:30:45.800
<v Speaker 1>get back to the The Eisenheim altarpiece of German Renaissance

0:30:45.840 --> 0:30:49.760
<v Speaker 1>paider painter at Matthias Gruenwald lived a fourteen seventy through

0:30:51.760 --> 0:30:54.520
<v Speaker 1>and uh, as with a number of these you know

0:30:54.880 --> 0:30:57.520
<v Speaker 1>older masters. You know, we don't know a whole lot

0:30:57.560 --> 0:31:01.960
<v Speaker 1>about his life. Uh. Most mostly his his work is

0:31:01.960 --> 0:31:05.600
<v Speaker 1>what still speaks to us. Right. So one panel illustrates

0:31:05.640 --> 0:31:08.720
<v Speaker 1>the temptation of St. Anthony in grotesque detail, with his

0:31:08.800 --> 0:31:13.000
<v Speaker 1>demon tormentors displaying clear skin ailments that are that are

0:31:13.040 --> 0:31:16.800
<v Speaker 1>clearly inspired by the skin ailments dealt with by the hospitallers. Yeah,

0:31:16.800 --> 0:31:20.640
<v Speaker 1>what were the details so that temptation My recollection is

0:31:20.680 --> 0:31:23.960
<v Speaker 1>that he basically went into the into the desert, into

0:31:24.000 --> 0:31:26.760
<v Speaker 1>the wilderness to to pray as you do, and so

0:31:26.880 --> 0:31:28.840
<v Speaker 1>kind of like Christ in the in the Gospel. Yeah,

0:31:28.880 --> 0:31:33.280
<v Speaker 1>but I I don't recall them making any particular offers,

0:31:33.400 --> 0:31:36.120
<v Speaker 1>like like the whole temptation of Christ. Of course, the

0:31:36.560 --> 0:31:39.240
<v Speaker 1>devil offers the you know, for Jesus to be the

0:31:39.320 --> 0:31:42.160
<v Speaker 1>king of the world and all that. Uh, there's there's

0:31:42.200 --> 0:31:43.720
<v Speaker 1>more of the death and offer on the table where

0:31:43.760 --> 0:31:46.840
<v Speaker 1>I think, uh St Anthony was just plagued by demons.

0:31:47.560 --> 0:31:49.720
<v Speaker 1>Do we get to turn these breads into stone? Or

0:31:51.400 --> 0:31:53.640
<v Speaker 1>now you might want to turn these breads into stones

0:31:53.720 --> 0:31:58.920
<v Speaker 1>if they are urgan infested deeds. Um. So yeah, so St.

0:31:58.920 --> 0:32:01.560
<v Speaker 1>Anthony is very much a part of the altarpiece. But

0:32:01.600 --> 0:32:04.160
<v Speaker 1>then we see this vision of the suffering Christ, which

0:32:04.200 --> 0:32:08.480
<v Speaker 1>we already mentioned, who clearly displays symptoms of the individuals

0:32:08.520 --> 0:32:13.240
<v Speaker 1>that were suffering in the monastery, covered with sores, gangernous flesh.

0:32:13.280 --> 0:32:17.000
<v Speaker 1>Even his hands and feet, uh, even though they're you know,

0:32:17.080 --> 0:32:21.880
<v Speaker 1>pierced by by nails. Uh, they're twisted and convulsed as

0:32:21.960 --> 0:32:26.320
<v Speaker 1>if one was suffering from convulsive right. And so it's

0:32:26.400 --> 0:32:29.680
<v Speaker 1>not part of the religious tradition of any Christians that

0:32:30.000 --> 0:32:33.000
<v Speaker 1>Christ actually suffered from margate poisoning. Like, that's not in

0:32:33.040 --> 0:32:36.680
<v Speaker 1>the Bible. That's not particularly a belief. This was just

0:32:36.720 --> 0:32:40.560
<v Speaker 1>sort of an interpretive lens of Gruenwald's right. Yeah. In fact,

0:32:40.600 --> 0:32:43.160
<v Speaker 1>I mean up until the thirteenth century, the predominant style

0:32:43.480 --> 0:32:46.240
<v Speaker 1>was was to depict Christ not even really suffering at all.

0:32:46.520 --> 0:32:48.400
<v Speaker 1>He would just be up there with his you know,

0:32:48.480 --> 0:32:53.000
<v Speaker 1>his eyes eyes open, seemings seemingly impervious to the physical torments.

0:32:53.000 --> 0:32:56.440
<v Speaker 1>It is only after that that you start displaying Jesus

0:32:56.480 --> 0:32:59.040
<v Speaker 1>as actually suffering, as a human would up there, as

0:32:59.080 --> 0:33:02.280
<v Speaker 1>opposed to just being above it like a God Um.

0:33:02.320 --> 0:33:07.280
<v Speaker 1>So really um, Gruenwald was just taking this uh to

0:33:07.360 --> 0:33:10.760
<v Speaker 1>the local level, you know, because he's surrounded by individuals

0:33:10.760 --> 0:33:13.400
<v Speaker 1>that are are suffering from urgotism and other scan elements,

0:33:13.400 --> 0:33:17.280
<v Speaker 1>and so historians believe that he actually used those patients

0:33:17.280 --> 0:33:21.960
<v Speaker 1>as his subjects, capturing clinical details UH and their abnormal

0:33:22.040 --> 0:33:27.400
<v Speaker 1>postures and using that as the model for not only

0:33:27.440 --> 0:33:31.760
<v Speaker 1>the demons assaulting St. Anthony, but but the suffering of

0:33:31.880 --> 0:33:36.120
<v Speaker 1>Christ himself. That's actually kind of a moving way of

0:33:36.160 --> 0:33:39.000
<v Speaker 1>thinking about how these people were grappling with their religion.

0:33:39.080 --> 0:33:42.840
<v Speaker 1>So if their idea is that, you know, what is

0:33:42.880 --> 0:33:45.840
<v Speaker 1>the significance of Christ, that it's you know, the powerful

0:33:45.880 --> 0:33:49.200
<v Speaker 1>God coming down to earth to suffer with humanity, it

0:33:49.200 --> 0:33:51.640
<v Speaker 1>would make sense that they would they would impart to

0:33:51.720 --> 0:33:56.000
<v Speaker 1>their vision of the suffering Servant, the suffering God, the

0:33:56.080 --> 0:33:58.360
<v Speaker 1>same things they were suffering from. It's sort of like

0:33:58.440 --> 0:34:01.680
<v Speaker 1>a bonding relation and ship they can form with the

0:34:01.720 --> 0:34:04.600
<v Speaker 1>God that they worship. Yeah, I mean, because ultimately you're

0:34:04.640 --> 0:34:07.560
<v Speaker 1>laying there on the floor, you're suffering from urgetism, You're

0:34:07.600 --> 0:34:11.600
<v Speaker 1>being attended to by these hospitallers. What kind of suffering

0:34:11.640 --> 0:34:13.000
<v Speaker 1>Christ do you want to look up at? You? Want

0:34:13.000 --> 0:34:15.239
<v Speaker 1>to see the serene like, oh, I hardly noticed I

0:34:15.280 --> 0:34:17.000
<v Speaker 1>have nails in me. You want to see the Oh

0:34:17.120 --> 0:34:20.040
<v Speaker 1>I'm I'm I'm crucified, but I'm you know, really buff

0:34:20.080 --> 0:34:22.880
<v Speaker 1>and otherwise healthy. Or do you want to see a

0:34:22.960 --> 0:34:25.200
<v Speaker 1>Christ that is suffering as you suffer? He knows what

0:34:25.320 --> 0:34:28.600
<v Speaker 1>it's like to have the limbs blacken and and to

0:34:28.719 --> 0:34:32.520
<v Speaker 1>feel the igny sassare. Yeah, yeah, I mean I agree.

0:34:32.520 --> 0:34:35.759
<v Speaker 1>I ultimately find it, you know, really really poignant. It

0:34:35.840 --> 0:34:38.520
<v Speaker 1>also makes me wonder how come we don't see like

0:34:38.560 --> 0:34:42.160
<v Speaker 1>a sort of modern first world problems version of Christ

0:34:42.280 --> 0:34:46.680
<v Speaker 1>on the Cross says most of us can't relate to severe, um,

0:34:46.719 --> 0:34:49.560
<v Speaker 1>you know, fleshly torment. Perhaps there's like a vision of

0:34:49.640 --> 0:34:52.680
<v Speaker 1>Christ that could be created where he just doesn't have

0:34:52.800 --> 0:34:54.919
<v Speaker 1>enough bars on his cell phone or is his phone

0:34:55.120 --> 0:34:57.680
<v Speaker 1>running out of batteries, you know, and because that kind

0:34:57.680 --> 0:35:00.840
<v Speaker 1>of suffering the modern millennial can you can relate to,

0:35:01.280 --> 0:35:06.880
<v Speaker 1>Let's not paint that picture. Uh speaking of painting pictures though, Um,

0:35:06.920 --> 0:35:12.399
<v Speaker 1>there are various other artistic interpretations of urgotism. Uh, there's

0:35:12.440 --> 0:35:14.799
<v Speaker 1>one that came up that I was really taken with.

0:35:14.920 --> 0:35:17.600
<v Speaker 1>Then it's just a minor when it's a woodcut, uh

0:35:17.920 --> 0:35:22.600
<v Speaker 1>titled St Anthony's Fire Ergotism by Johannes Vichland and this

0:35:22.719 --> 0:35:27.640
<v Speaker 1>is from around four nine, probably thirties, somewhere in there.

0:35:27.800 --> 0:35:29.960
<v Speaker 1>And we see a man with a flaming ganger in

0:35:30.000 --> 0:35:32.560
<v Speaker 1>his hand, appealing to St. Anthony. So it looks kind

0:35:32.560 --> 0:35:35.560
<v Speaker 1>of like like it reminds me the hand of Glory,

0:35:35.719 --> 0:35:37.920
<v Speaker 1>you know. Oh I haven't seen this. Yeah, yeah, here

0:35:37.960 --> 0:35:40.920
<v Speaker 1>it is. Here's the copy of it. Oh, that is amazing.

0:35:41.480 --> 0:35:44.359
<v Speaker 1>So you have the saint is very tall, and then

0:35:44.360 --> 0:35:47.520
<v Speaker 1>there's like a child sort of at knee level reaching

0:35:47.600 --> 0:35:51.440
<v Speaker 1>up with the crippled limbs, but a flaming hand on

0:35:51.600 --> 0:35:57.160
<v Speaker 1>fire beseeching the saint. And then uh, then there's also

0:35:57.239 --> 0:36:01.560
<v Speaker 1>of course U Hieronymous Bosh, who is an even more

0:36:01.640 --> 0:36:04.320
<v Speaker 1>towering figure in the history of Western art. Yes, so

0:36:04.360 --> 0:36:06.480
<v Speaker 1>the idea here is a little bit different, not so

0:36:06.600 --> 0:36:09.600
<v Speaker 1>much that the artist was inspired by a world of

0:36:09.680 --> 0:36:13.279
<v Speaker 1>people suffering from argotism, but perhaps that the artist might

0:36:13.320 --> 0:36:16.719
<v Speaker 1>have been suffering from argotism himself. Indeed, though, I mean

0:36:16.719 --> 0:36:19.160
<v Speaker 1>there are there are some works by Bosch, such as

0:36:19.200 --> 0:36:21.120
<v Speaker 1>the Procession of the Cripples, which features a number of

0:36:21.120 --> 0:36:25.040
<v Speaker 1>afflicted bodies uh, and at least three of them uh

0:36:25.120 --> 0:36:27.200
<v Speaker 1>seemed to be suffering from organtism. So he did a

0:36:27.200 --> 0:36:29.960
<v Speaker 1>little bit at least of observing argotism in the world

0:36:30.000 --> 0:36:33.080
<v Speaker 1>around him. Sure, I didn't mean to rule that out, no, no, no,

0:36:33.400 --> 0:36:36.719
<v Speaker 1>um And just to put Bosch in his place historically

0:36:37.080 --> 0:36:41.440
<v Speaker 1>fourteen fifty to fifteen sixteen, early, highly highly influential, a

0:36:41.480 --> 0:36:47.239
<v Speaker 1>Netherlandish painter known for his surrealistic, nightmarish and cryptic imagery. Um.

0:36:47.280 --> 0:36:49.680
<v Speaker 1>And this was very much a time when argotism was

0:36:49.800 --> 0:36:53.399
<v Speaker 1>epidemic uh in the Netherlands. Yeah, if you haven't seen

0:36:53.480 --> 0:36:58.480
<v Speaker 1>Bosch's paintings, actually you probably have seen them. Here's here's

0:36:58.480 --> 0:37:00.799
<v Speaker 1>the clue that you're looking at a Bosch painting. Are

0:37:00.840 --> 0:37:04.520
<v Speaker 1>there lots of little people in it? And is it crazy? Yeah?

0:37:04.680 --> 0:37:08.160
<v Speaker 1>Are there like crazy bird demons, chamber pots on their head?

0:37:08.760 --> 0:37:12.440
<v Speaker 1>Like just those just surrealistic visions of medieval hell coupled

0:37:12.440 --> 0:37:17.719
<v Speaker 1>with the detailed depictions of peasants and stunning realistic landscapes.

0:37:18.280 --> 0:37:20.120
<v Speaker 1>Like that's pretty much Bosch in a nutshell. And you

0:37:20.200 --> 0:37:24.040
<v Speaker 1>would probably see his work uh on like like one

0:37:24.040 --> 0:37:28.719
<v Speaker 1>out of five college dorm room walls. Not to I

0:37:28.719 --> 0:37:31.120
<v Speaker 1>mean not not just to say his work isn't brilliant,

0:37:31.120 --> 0:37:33.319
<v Speaker 1>because it is. I mean, I still I still can get.

0:37:33.360 --> 0:37:36.280
<v Speaker 1>You can just lose myself staring into a Bosch painting

0:37:36.280 --> 0:37:38.799
<v Speaker 1>because there it's also it's just cryptic. There's so many

0:37:38.840 --> 0:37:41.719
<v Speaker 1>symbols at play, many of which would make more sense

0:37:41.719 --> 0:37:45.279
<v Speaker 1>to a contemporary viewer, particularly in the clergy or you know,

0:37:45.320 --> 0:37:47.719
<v Speaker 1>a lay patron. There may be a little more lost

0:37:47.760 --> 0:37:51.799
<v Speaker 1>on us today, but there's a lot going on. Uh

0:37:51.800 --> 0:37:53.680
<v Speaker 1>and in our mind just has to grapple with it.

0:37:53.719 --> 0:37:56.000
<v Speaker 1>When we were one of his paintings, Yeah, they're they're

0:37:56.080 --> 0:38:00.239
<v Speaker 1>dark and highly imaginative. They make a rob zombie music

0:38:00.320 --> 0:38:04.080
<v Speaker 1>video look dull by comparison. In fact, he has been

0:38:04.080 --> 0:38:06.400
<v Speaker 1>His work has been a reference in a couple of

0:38:06.920 --> 0:38:09.560
<v Speaker 1>music videos. I think Metallica did one where they had

0:38:09.680 --> 0:38:13.799
<v Speaker 1>some uh some some Bosch imagery going on, and then

0:38:14.320 --> 0:38:19.279
<v Speaker 1>Buckethead did a music video that is just basically one

0:38:19.320 --> 0:38:23.120
<v Speaker 1>of Bosch's paintings animated. Yeah, it's it's pretty pretty stunning.

0:38:24.520 --> 0:38:28.440
<v Speaker 1>So so what's the argument here, Well, if you look

0:38:28.480 --> 0:38:32.799
<v Speaker 1>at Bosch's own Temptation of St. Anthony triptych, you'll see

0:38:32.800 --> 0:38:36.279
<v Speaker 1>that it features people with amputated and mummified feet. You

0:38:36.360 --> 0:38:42.480
<v Speaker 1>also see a half human, half vegetable tree woman creature. Uh.

0:38:42.600 --> 0:38:45.480
<v Speaker 1>You see an egg shaped structure belching smoke and flame.

0:38:46.080 --> 0:38:48.000
<v Speaker 1>And there's an argument here that in the sort of

0:38:48.040 --> 0:38:52.359
<v Speaker 1>the the code of the painting, that the vegetable human

0:38:52.440 --> 0:38:55.600
<v Speaker 1>is actually a man drake, which is if you if

0:38:55.600 --> 0:38:58.560
<v Speaker 1>you've ever seen the works of Guermo del Toro, you

0:38:58.560 --> 0:39:00.879
<v Speaker 1>know the man drake or a ry Potter, Right, It's

0:39:00.920 --> 0:39:04.919
<v Speaker 1>it's kind of human looking. The root and the herb

0:39:05.040 --> 0:39:07.920
<v Speaker 1>was used to alleviate the pains of Saint Anthony's fire

0:39:08.239 --> 0:39:11.000
<v Speaker 1>by the hospitalers. So and then on top of that,

0:39:11.080 --> 0:39:15.600
<v Speaker 1>the egg shaped structure was possibly an apothecaries retort the

0:39:15.640 --> 0:39:20.960
<v Speaker 1>distillery used to reduce medical herbs. So do you actually

0:39:21.000 --> 0:39:25.120
<v Speaker 1>think Bosh was suffering from the like the hallucinatory visions

0:39:25.200 --> 0:39:28.839
<v Speaker 1>of ergan poisoning? Um? I can to think not. I mean,

0:39:28.880 --> 0:39:32.560
<v Speaker 1>some some people make a you know, rather impassioned argument

0:39:32.640 --> 0:39:36.239
<v Speaker 1>for that, or even I've seen some arguments that he

0:39:36.600 --> 0:39:40.960
<v Speaker 1>maybe used some sort of ergic derived potion as part

0:39:41.000 --> 0:39:43.080
<v Speaker 1>of some sort of a cult he was in. Maybe

0:39:43.080 --> 0:39:46.920
<v Speaker 1>he was aligned with the Cathars. Uh. Yeah, that's almost

0:39:46.960 --> 0:39:50.120
<v Speaker 1>like what would be the Renaissance equivalent of steampunk. I

0:39:50.160 --> 0:39:53.240
<v Speaker 1>don't know alchemy alchemy, I guess, yeah, I mean certainly

0:39:53.239 --> 0:39:57.040
<v Speaker 1>there are a lot of you know, arguments of involving

0:39:57.440 --> 0:40:02.480
<v Speaker 1>Bosch's involvement with with alchemy. But but yeah, I think

0:40:02.480 --> 0:40:05.400
<v Speaker 1>it's the kind of gets back to the whole Dancing

0:40:05.440 --> 0:40:09.040
<v Speaker 1>Mania Salem Witchcraft thing, right, like the to to point

0:40:09.040 --> 0:40:12.719
<v Speaker 1>it to Ergotism is the single smoking gun for this uh,

0:40:12.800 --> 0:40:16.480
<v Speaker 1>for this artist and his his imagination. It's it's too easy,

0:40:16.560 --> 0:40:19.080
<v Speaker 1>and it's it's kind of limiting, you know. Yeah, with

0:40:19.080 --> 0:40:21.800
<v Speaker 1>with a lot of these hypotheses, I think very often

0:40:21.840 --> 0:40:25.040
<v Speaker 1>you have to say, well, that's interesting, but I mean

0:40:25.120 --> 0:40:27.880
<v Speaker 1>we we just don't really know, yeah, and we ultimately

0:40:27.920 --> 0:40:31.960
<v Speaker 1>know very little about the Hieronymous Bosh's life. It's just

0:40:32.239 --> 0:40:35.200
<v Speaker 1>he's ultimately kind of a blank canvas, and you can

0:40:35.280 --> 0:40:37.200
<v Speaker 1>in his room enough on that point canvas to put

0:40:37.200 --> 0:40:39.080
<v Speaker 1>in anything you want to be a uh, you know,

0:40:39.160 --> 0:40:42.000
<v Speaker 1>involvement in some sort of a strange uh um, you know,

0:40:42.000 --> 0:40:45.279
<v Speaker 1>psychedelic cult or you know, some some ergot poisoning in

0:40:45.320 --> 0:40:48.080
<v Speaker 1>his time, which is certainly possible given where he lived

0:40:48.120 --> 0:40:51.880
<v Speaker 1>and when he lived. But it's also just as possible

0:40:52.239 --> 0:40:56.520
<v Speaker 1>that he was just a really imaginative, creative, highly skilled

0:40:56.640 --> 0:40:59.719
<v Speaker 1>artist who was also who was working with with with

0:40:59.760 --> 0:41:04.560
<v Speaker 1>many established symbols and motifs but also embellishing them, uh,

0:41:04.640 --> 0:41:08.560
<v Speaker 1>in just a purely creative way. It's also entirely possible

0:41:08.560 --> 0:41:11.520
<v Speaker 1>that he did suffer from some sort of hallucination or another.

0:41:12.000 --> 0:41:16.440
<v Speaker 1>But there are so many reasons that you could experience

0:41:16.480 --> 0:41:19.279
<v Speaker 1>an hallucination. There's so many ways that you could enter

0:41:19.360 --> 0:41:22.960
<v Speaker 1>this altered mind, uh mind space that don't involve the

0:41:23.000 --> 0:41:26.480
<v Speaker 1>consumption of ERG or any psychedelic sustenance. Sure, and then

0:41:26.520 --> 0:41:29.839
<v Speaker 1>of course there's just the hypothesis that, like Gruenwald, this

0:41:29.920 --> 0:41:33.360
<v Speaker 1>was his environment. He was living in a world of

0:41:33.360 --> 0:41:37.560
<v Speaker 1>of mummified limbs falling off of human you know, like

0:41:37.760 --> 0:41:41.040
<v Speaker 1>still living people, and people suffering from madness thinking that

0:41:41.120 --> 0:41:45.359
<v Speaker 1>spiders were all over their skin, right, I mean you know, yeah,

0:41:45.400 --> 0:41:47.239
<v Speaker 1>I mean, as we see in with the procession of

0:41:47.239 --> 0:41:49.280
<v Speaker 1>the cripples. In other words, I mean, he was very

0:41:49.360 --> 0:41:53.440
<v Speaker 1>interested in the common man and what the common man

0:41:53.719 --> 0:41:57.080
<v Speaker 1>dealt with and suffered with in life, and uh, and

0:41:57.160 --> 0:42:01.200
<v Speaker 1>so that's shading his depiction of these very religious motifs.

0:42:01.840 --> 0:42:04.880
<v Speaker 1>But again, we'll never know for sure, because Bosh doesn't

0:42:04.880 --> 0:42:06.960
<v Speaker 1>say anything about it. The only way he speaks with

0:42:07.040 --> 0:42:10.120
<v Speaker 1>us is through these these these brilliant works of art

0:42:10.200 --> 0:42:12.960
<v Speaker 1>that are still just as powerful today as they were

0:42:13.760 --> 0:42:16.520
<v Speaker 1>back when he was alive. Isn't it strange that such

0:42:16.560 --> 0:42:21.400
<v Speaker 1>a tiny little organism UH that doesn't even directly attack humans,

0:42:21.520 --> 0:42:24.160
<v Speaker 1>you know, like it's target is the rye, Yeah, which

0:42:24.200 --> 0:42:28.240
<v Speaker 1>is collaterally exactly where collateral damage. This little purple witch

0:42:28.360 --> 0:42:31.960
<v Speaker 1>finger extending out of a out of a plant has

0:42:32.000 --> 0:42:34.560
<v Speaker 1>caused so much trouble for humanity and for their you know,

0:42:34.640 --> 0:42:38.719
<v Speaker 1>all the other animals. Indeed, all right, so there you

0:42:38.760 --> 0:42:41.920
<v Speaker 1>have it. Organism in a nutshell. Um, look at the

0:42:41.920 --> 0:42:45.840
<v Speaker 1>way it is UH has influenced our history, our our biology,

0:42:46.440 --> 0:42:50.160
<v Speaker 1>our art and religion. Um. Really fascinating stuff. If you

0:42:50.160 --> 0:42:52.000
<v Speaker 1>would like to see some of these images that we've

0:42:52.000 --> 0:42:54.120
<v Speaker 1>been discussing here, check out the landing page for this

0:42:54.200 --> 0:42:57.160
<v Speaker 1>episode at stuff to Blow your Mind dot com. That's

0:42:57.160 --> 0:42:59.040
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0:42:59.080 --> 0:43:02.080
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0:43:02.120 --> 0:43:05.440
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0:43:05.480 --> 0:43:08.280
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0:43:08.320 --> 0:43:11.840
<v Speaker 1>if you use those social media systems, and if you

0:43:11.880 --> 0:43:15.160
<v Speaker 1>have any interesting thoughts about urgotism or any other strange

0:43:15.160 --> 0:43:19.480
<v Speaker 1>psychedelic substances that have somehow penetrated our diet throughout the

0:43:19.600 --> 0:43:22.440
<v Speaker 1>years and throughout the centuries, and want to talk to

0:43:22.520 --> 0:43:24.480
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0:43:24.520 --> 0:43:30.840
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0:43:30.880 --> 0:43:33.360
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0:43:33.400 --> 0:43:40.000
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