1 00:00:00,120 --> 00:00:01,680 Speaker 1: Lots going on here today. 2 00:00:02,120 --> 00:00:04,440 Speaker 2: We want to pivot hard here and we want to 3 00:00:04,480 --> 00:00:07,920 Speaker 2: talk pharmaceuticals and we want to talk drugs and all 4 00:00:07,920 --> 00:00:08,639 Speaker 2: that kind of stuff. 5 00:00:08,680 --> 00:00:10,119 Speaker 1: And we can do that well. And one of the 6 00:00:10,160 --> 00:00:11,320 Speaker 1: biggest winners of the day. 7 00:00:11,200 --> 00:00:14,360 Speaker 2: Biggest winners of the day, Stefan Bansel, CEO of Moderna. 8 00:00:14,480 --> 00:00:17,279 Speaker 2: That is a Nasdaq trade of stock. Mr NA is 9 00:00:17,320 --> 00:00:21,360 Speaker 2: the ticker to put into your Bloomberg terminal. You know nobody, 10 00:00:21,440 --> 00:00:23,799 Speaker 2: I guess when you sit around your Thanksgiving table, everybody 11 00:00:23,840 --> 00:00:25,320 Speaker 2: likes to just complain about. 12 00:00:25,120 --> 00:00:27,720 Speaker 1: Drug prices, right, everybody does it. It's crossed the aisle. 13 00:00:27,840 --> 00:00:30,600 Speaker 2: But I turned it around a couple years ago and said, okay, 14 00:00:30,600 --> 00:00:33,040 Speaker 2: we can do that because we always like to complain 15 00:00:33,080 --> 00:00:33,920 Speaker 2: about drug prices. 16 00:00:34,400 --> 00:00:35,760 Speaker 1: But these guys in the farmer. 17 00:00:35,640 --> 00:00:39,200 Speaker 2: In the biotech industry, man, did they come through with COVID. 18 00:00:39,240 --> 00:00:39,440 Speaker 1: Yeah. 19 00:00:39,479 --> 00:00:42,600 Speaker 3: I think actually, as a society, we were all a 20 00:00:42,640 --> 00:00:43,800 Speaker 3: little bit relieved. 21 00:00:44,080 --> 00:00:46,559 Speaker 2: I'm like, in twelve months, these guys came up with 22 00:00:46,600 --> 00:00:49,640 Speaker 2: a vaccine. I mean, who does that, But you guys did. 23 00:00:49,880 --> 00:00:50,680 Speaker 1: Thank you very much. 24 00:00:50,760 --> 00:00:52,159 Speaker 2: Thank you to the fighter for folks and all the 25 00:00:52,200 --> 00:00:55,400 Speaker 2: other farmer and biotech folks out there. That man did 26 00:00:55,400 --> 00:00:58,800 Speaker 2: they come through with that vaccine appreciated. Now what are 27 00:00:58,800 --> 00:01:01,360 Speaker 2: you doing? Modarn now tells you guys have your R 28 00:01:01,360 --> 00:01:04,360 Speaker 2: and D day today, you bring out all your new 29 00:01:04,400 --> 00:01:07,759 Speaker 2: stuff for your investors, for your stakeholders. What's the big 30 00:01:07,760 --> 00:01:09,119 Speaker 2: message for your R and D day. 31 00:01:09,000 --> 00:01:11,640 Speaker 4: Today is that we're not a COVID company. 32 00:01:12,360 --> 00:01:14,800 Speaker 1: Yes for the kind of word yes, thank you though. 33 00:01:15,160 --> 00:01:18,679 Speaker 4: And the money platform company and the platform is firing 34 00:01:18,720 --> 00:01:22,760 Speaker 4: on every cylinders today went on seeing positive fluid data 35 00:01:22,880 --> 00:01:25,240 Speaker 4: in phase three. So if you think about it in 36 00:01:25,319 --> 00:01:28,040 Speaker 4: terms of vaccines, we are free out of free COVID 37 00:01:28,080 --> 00:01:32,600 Speaker 4: working URSV file to VFDA and to the positive flugh data. 38 00:01:33,480 --> 00:01:39,360 Speaker 4: In cancer, we are now products showing forty four percent improvement. 39 00:01:39,480 --> 00:01:41,920 Speaker 4: This is the best drug available to patients today, which 40 00:01:41,920 --> 00:01:46,200 Speaker 4: is immunotherapy in melanomas kin cancer. And we're going to 41 00:01:46,200 --> 00:01:48,680 Speaker 4: start before the end of the year a phase free 42 00:01:48,720 --> 00:01:52,240 Speaker 4: study in learn cancer. Okay, cancer, we really going to 43 00:01:52,280 --> 00:01:53,160 Speaker 4: transform as well. 44 00:01:53,920 --> 00:01:58,160 Speaker 3: First that is that, by the way, because of MR 45 00:01:58,240 --> 00:02:00,720 Speaker 3: and A technology. And I'll just remind listeners we are 46 00:02:00,720 --> 00:02:04,400 Speaker 3: talking with Stefan Bonsel right now. He's the chief executive 47 00:02:04,400 --> 00:02:08,760 Speaker 3: officer of Moderna. And as you said, you're not just 48 00:02:08,800 --> 00:02:12,320 Speaker 3: a COVID company. You did have an mRNA vaccine for 49 00:02:12,440 --> 00:02:15,480 Speaker 3: COVID that maybe saved the world a lot more pain 50 00:02:15,520 --> 00:02:18,000 Speaker 3: than it would have seen. But you also have a 51 00:02:18,040 --> 00:02:20,679 Speaker 3: flu vaccine that is driving the stock up today six 52 00:02:20,760 --> 00:02:25,520 Speaker 3: and a half percent, and cancer treatments. 53 00:02:25,000 --> 00:02:27,200 Speaker 1: That we hope, we all hope, I think are. 54 00:02:27,120 --> 00:02:30,040 Speaker 3: Going to be successful and could drive revenue another fifteen 55 00:02:30,080 --> 00:02:32,440 Speaker 3: billion starting in twenty twenty eight. So tell us about 56 00:02:32,440 --> 00:02:35,280 Speaker 3: the mRNA technology that we all kind of learned about 57 00:02:35,280 --> 00:02:36,080 Speaker 3: a couple of years ago. 58 00:02:36,280 --> 00:02:39,800 Speaker 4: Sure. So, Emania, as you learned about, is an information 59 00:02:39,840 --> 00:02:43,840 Speaker 4: in molecule. We basically code in that molecule what protein 60 00:02:43,919 --> 00:02:46,640 Speaker 4: we want your body to make that would be your drug, 61 00:02:46,760 --> 00:02:49,920 Speaker 4: your medicine. And in cancer, now what we have shown 62 00:02:50,120 --> 00:02:55,040 Speaker 4: is a huge impact on survival and being able to 63 00:02:55,080 --> 00:02:57,640 Speaker 4: note have recurrence of disease compared to the best drugs 64 00:02:57,639 --> 00:03:00,360 Speaker 4: available to do to patients. And the first chap for 65 00:03:00,480 --> 00:03:05,000 Speaker 4: us after infectious is vaccine and cancer is real genetic disease. 66 00:03:05,800 --> 00:03:08,239 Speaker 1: We are now free, out of free, real. 67 00:03:08,160 --> 00:03:11,519 Speaker 4: Genetic disease, showing positive data in kids with those diseases 68 00:03:11,560 --> 00:03:13,880 Speaker 4: that have no hope today, zero hope. 69 00:03:14,639 --> 00:03:18,280 Speaker 2: All right, So back to the flu because it's we're 70 00:03:18,320 --> 00:03:21,760 Speaker 2: getting into flu season. What is your flu vaccine? What 71 00:03:21,919 --> 00:03:23,000 Speaker 2: is new, what is different? 72 00:03:24,240 --> 00:03:26,680 Speaker 1: Just tell us about what is SAT today. Why are 73 00:03:26,680 --> 00:03:28,639 Speaker 1: people so excited about the flu vaccine? 74 00:03:29,000 --> 00:03:31,200 Speaker 4: Because first we're going to be able to participate and 75 00:03:31,240 --> 00:03:34,840 Speaker 4: provide a very high efficacy flu vaccine. What we've showed 76 00:03:34,880 --> 00:03:37,880 Speaker 4: in actually over studies is that actually it's as good 77 00:03:37,920 --> 00:03:40,160 Speaker 4: as the best vaccine on the market for flu. But 78 00:03:40,280 --> 00:03:42,480 Speaker 4: what people I think I excited about is the idea 79 00:03:42,520 --> 00:03:45,840 Speaker 4: of combination, Meaning we're going to show before the end 80 00:03:45,840 --> 00:03:50,160 Speaker 4: of the year, flu and covid combine in a single shot, 81 00:03:50,480 --> 00:03:52,440 Speaker 4: so in the following years you won't have to go 82 00:03:52,480 --> 00:03:53,880 Speaker 4: and get a flu shot in one arm and the 83 00:03:53,920 --> 00:03:56,400 Speaker 4: covid shot in your arm. They'll be combined. And then 84 00:03:56,480 --> 00:03:58,800 Speaker 4: over time we're going to keep adding more and more 85 00:03:59,000 --> 00:04:03,520 Speaker 4: respiratory viars like OSV to the combination as well, so 86 00:04:03,560 --> 00:04:05,280 Speaker 4: that you can have only one shot early in the 87 00:04:05,280 --> 00:04:07,320 Speaker 4: four at the pharmacy and then you have a happy 88 00:04:07,320 --> 00:04:08,800 Speaker 4: four or in winter you're not sick. 89 00:04:09,560 --> 00:04:12,120 Speaker 2: So but this is for next year. This is not 90 00:04:12,160 --> 00:04:13,120 Speaker 2: for this conclusing. 91 00:04:13,240 --> 00:04:15,600 Speaker 1: Okay, got it. Just want to get clear on the timing. 92 00:04:15,680 --> 00:04:16,839 Speaker 1: You can still get your flu vaccine. 93 00:04:16,839 --> 00:04:18,359 Speaker 2: For this, I'm gonna go down to LL two and 94 00:04:18,360 --> 00:04:20,160 Speaker 2: get my flu vaccine. I mean, who doesn't do that? 95 00:04:20,200 --> 00:04:25,719 Speaker 2: But so with mr mr Na tech technology, what's it 96 00:04:25,800 --> 00:04:28,039 Speaker 2: three to five years down the road, what do you 97 00:04:28,080 --> 00:04:30,200 Speaker 2: expect that technology to tackle next? 98 00:04:30,240 --> 00:04:34,559 Speaker 4: Maybe? So we're announcing today at Adday that we should 99 00:04:34,640 --> 00:04:37,599 Speaker 4: launch fifteen new drug in the next five years. 100 00:04:37,680 --> 00:04:39,320 Speaker 2: Fifteen new drugs in the next five. 101 00:04:39,240 --> 00:04:43,000 Speaker 4: Years now incredible across cancer in fift disease and genetic disease. 102 00:04:43,440 --> 00:04:46,680 Speaker 4: We're also working on an autoimmune disease I think althatories, 103 00:04:46,760 --> 00:04:49,720 Speaker 4: chron disease, and so on. We believe we're going to 104 00:04:49,760 --> 00:04:53,839 Speaker 4: bring fifteen more drugs on top of forty we have 105 00:04:54,240 --> 00:04:57,800 Speaker 4: in development fifty five zero okay from the lab into 106 00:04:57,880 --> 00:04:59,600 Speaker 4: the clinic in the next five years or on ten 107 00:04:59,640 --> 00:05:02,720 Speaker 4: new drug per year moving from the labs into developments. 108 00:05:02,720 --> 00:05:05,560 Speaker 4: So what you see here is a true platform. There 109 00:05:05,560 --> 00:05:07,920 Speaker 4: has never been platform in the biotech far my industry. 110 00:05:07,960 --> 00:05:09,839 Speaker 4: As you know, most drugs go to the clinic. Yep, 111 00:05:09,920 --> 00:05:13,119 Speaker 4: they're failed. Ninety percent of a drug starting at phase 112 00:05:13,160 --> 00:05:17,560 Speaker 4: one will never get launched. Okay, look at Modana because 113 00:05:17,600 --> 00:05:20,360 Speaker 4: of our platform. Because m money is an information molecule. 114 00:05:20,800 --> 00:05:22,800 Speaker 4: We are free out of three in vaccines, we are 115 00:05:22,839 --> 00:05:27,000 Speaker 4: three out of three in real genetic disease cancer. Incredible 116 00:05:27,040 --> 00:05:29,080 Speaker 4: improvements and it's just the beginning, all right. 117 00:05:29,120 --> 00:05:32,599 Speaker 3: This is all because of the mRNA technology. And I 118 00:05:32,640 --> 00:05:36,479 Speaker 3: have a funding question. Then what happens if you know 119 00:05:36,520 --> 00:05:40,840 Speaker 3: the COVID vaccine revenues don't meet your expectations? 120 00:05:40,839 --> 00:05:43,040 Speaker 1: Can you still fund that kind of growth? 121 00:05:43,480 --> 00:05:45,000 Speaker 4: Sure? I mean, if you look at it, we say 122 00:05:45,040 --> 00:05:47,040 Speaker 4: that this year we should be six to eight billion 123 00:05:47,080 --> 00:05:51,479 Speaker 4: dollar cells, which is still a very significant number. For turnover, 124 00:05:52,040 --> 00:05:54,880 Speaker 4: we are fourteen billion dollar on a bunch it that 125 00:05:55,000 --> 00:05:57,560 Speaker 4: we got through the COVID sales over the last two years. 126 00:05:57,839 --> 00:05:59,840 Speaker 4: And so we can find around with think twenty five 127 00:05:59,839 --> 00:06:03,000 Speaker 4: bi of r D growth by cash directing, by the 128 00:06:03,000 --> 00:06:06,279 Speaker 4: business and the balance sheet. And we will also not 129 00:06:06,360 --> 00:06:08,760 Speaker 4: be shy to partner if we have to. We're obsessed 130 00:06:08,800 --> 00:06:11,320 Speaker 4: about getting those drugs to patients to the finish line. 131 00:06:11,800 --> 00:06:13,880 Speaker 4: But if you look at for example, with Vertex, we 132 00:06:14,040 --> 00:06:17,800 Speaker 4: partnered for cystic fibros it's for inhale, the money getting 133 00:06:17,800 --> 00:06:19,960 Speaker 4: to the lung of a kid that have cistic fibrosis 134 00:06:20,320 --> 00:06:24,240 Speaker 4: by inhalation. We develop that technology, yet another fourth cylinder 135 00:06:24,240 --> 00:06:26,840 Speaker 4: for moderna to develop a new family of drugs. And 136 00:06:26,880 --> 00:06:28,520 Speaker 4: so that's what we're trying to do is push a 137 00:06:28,560 --> 00:06:30,920 Speaker 4: boundary of science, get more and more drugs and if 138 00:06:30,920 --> 00:06:32,080 Speaker 4: we have to partner, we'll partner. 139 00:06:32,120 --> 00:06:33,680 Speaker 1: But it's expensive to do. 140 00:06:33,920 --> 00:06:39,440 Speaker 3: And you know, because of recent legislation the United States, 141 00:06:40,240 --> 00:06:42,520 Speaker 3: the bidance stretchers past, the United States is going to 142 00:06:42,800 --> 00:06:47,320 Speaker 3: not only negotiate prices with drug makers, but set prices 143 00:06:47,880 --> 00:06:48,920 Speaker 3: with drug makers. 144 00:06:50,480 --> 00:06:52,920 Speaker 1: Is that a concern to you very much? 145 00:06:52,960 --> 00:06:55,919 Speaker 4: So as the rest of the industry, as voiced, you 146 00:06:55,960 --> 00:06:59,800 Speaker 4: cannot set prices because r D is risky. As we 147 00:06:59,839 --> 00:07:04,520 Speaker 4: just talked about ninety percent of drugs entering the clinic failure, 148 00:07:05,480 --> 00:07:08,000 Speaker 4: very high failure rate of the industry as a whole. 149 00:07:08,279 --> 00:07:10,320 Speaker 4: If you start to set price and not look at 150 00:07:10,320 --> 00:07:12,800 Speaker 4: the value that is bringing by the drugs, you're going 151 00:07:12,880 --> 00:07:16,080 Speaker 4: to reduce the ability of parmasty coreent bytech companies to 152 00:07:16,160 --> 00:07:18,480 Speaker 4: invest in innovation, and that's a big worry. 153 00:07:18,600 --> 00:07:20,400 Speaker 1: But they're going to set prices, So how are you 154 00:07:20,440 --> 00:07:21,160 Speaker 1: going to deal with it? 155 00:07:21,560 --> 00:07:24,000 Speaker 4: So we just need to keep innovating and figure out 156 00:07:24,080 --> 00:07:28,520 Speaker 4: ways to go after smaller disease type selling around the world. 157 00:07:28,880 --> 00:07:31,160 Speaker 4: Because again the US of course is the number one 158 00:07:31,160 --> 00:07:34,160 Speaker 4: market in the world, but other markets are also very important, 159 00:07:34,280 --> 00:07:37,520 Speaker 4: like Europe, you know, Japan, and so we're going to 160 00:07:37,560 --> 00:07:38,840 Speaker 4: have to grow internationally as well. 161 00:07:38,840 --> 00:07:39,600 Speaker 1: But it's a big issue. 162 00:07:39,640 --> 00:07:41,280 Speaker 4: I'm worried about it, all right. 163 00:07:41,320 --> 00:07:43,600 Speaker 2: How about I always joke that in my next life 164 00:07:43,600 --> 00:07:45,600 Speaker 2: I want to come back as a healthcare m and 165 00:07:45,600 --> 00:07:47,800 Speaker 2: a banker because every Monday we come in and there's 166 00:07:47,840 --> 00:07:50,600 Speaker 2: another healthcare deal that you are one of your competitors. 167 00:07:50,640 --> 00:07:55,000 Speaker 2: Do is there something that you need to buy in 168 00:07:55,040 --> 00:07:56,840 Speaker 2: the next couple of years to get to where you 169 00:07:56,880 --> 00:07:59,040 Speaker 2: want to go that maybe is not in your pipeline 170 00:07:59,080 --> 00:07:59,520 Speaker 2: right now. 171 00:08:00,040 --> 00:08:02,040 Speaker 4: So what is cool about Amanie is we are the 172 00:08:02,040 --> 00:08:04,960 Speaker 4: world leader in amani. Even BioNTech, which is a great company, 173 00:08:05,400 --> 00:08:07,840 Speaker 4: they are doing small molecule, large molecule, a lot of 174 00:08:07,840 --> 00:08:11,559 Speaker 4: different technologies. We are only doing ammonie. What we're doing 175 00:08:11,600 --> 00:08:14,000 Speaker 4: for OBD activity is that a buying We bought a 176 00:08:14,000 --> 00:08:17,600 Speaker 4: company in Japan over the Christmas break the cool technology 177 00:08:17,600 --> 00:08:20,960 Speaker 4: to make our em money operating system stronger and bigger 178 00:08:21,040 --> 00:08:23,200 Speaker 4: so we can do more drugs. We are now some 179 00:08:23,160 --> 00:08:26,400 Speaker 4: one there dealing cancer with a company in Germany that 180 00:08:26,480 --> 00:08:29,760 Speaker 4: has very cool science and biology that we can code 181 00:08:29,880 --> 00:08:32,640 Speaker 4: into the Emmanni molecule to do new drugs. So this 182 00:08:32,800 --> 00:08:36,360 Speaker 4: will do to expand the potential of impacting patients. 183 00:08:37,080 --> 00:08:38,800 Speaker 1: All right, excellent to have you in here. I really 184 00:08:38,840 --> 00:08:39,440 Speaker 1: appreciate it. 185 00:08:39,440 --> 00:08:41,360 Speaker 3: And I know you're going to go on television in 186 00:08:41,440 --> 00:08:44,400 Speaker 3: just a moment, so our listeners will be able to 187 00:08:44,920 --> 00:08:48,040 Speaker 3: watch you with Alex Steele and Guy Johnson on the 188 00:08:48,120 --> 00:08:54,160 Speaker 3: European clothes. Just a fascinating discussion and also a fascinating 189 00:08:54,160 --> 00:08:55,880 Speaker 3: move in a stock up six point seven percent. 190 00:08:55,960 --> 00:08:58,320 Speaker 2: Yeah about that, Stefan Bansel, thank you so much for 191 00:08:58,400 --> 00:09:00,560 Speaker 2: joining us stuff on as the CEO of more Moderna 192 00:09:00,600 --> 00:09:03,360 Speaker 2: again the taker symbol for your stock jockeys out there, 193 00:09:03,559 --> 00:09:05,320 Speaker 2: mr Na, we appreciate that. 194 00:09:05,840 --> 00:09:06,520 Speaker 1: Thank you so much. 195 00:09:06,640 --> 00:09:08,680 Speaker 2: All Right, looking ahead of here at this market here 196 00:09:08,720 --> 00:09:12,120 Speaker 2: we are pretty much unchanged here. Uh so you know 197 00:09:12,160 --> 00:09:14,200 Speaker 2: we're gonna be very interesting to see how this market. 198 00:09:14,200 --> 00:09:16,400 Speaker 2: But you know Moderna that again that stock, as you mentioned, 199 00:09:16,640 --> 00:09:20,880 Speaker 2: Matt up six percent today, down thirty seven percent year 200 00:09:20,960 --> 00:09:21,400 Speaker 2: to date.