1 00:00:00,800 --> 00:00:03,239 Speaker 1: Hey, everybody, This is Chuck and welcome to this week's 2 00:00:03,840 --> 00:00:08,360 Speaker 1: s Y s K Select episode all about allergies. And 3 00:00:08,640 --> 00:00:11,360 Speaker 1: the reason I picked this one is because, although I 4 00:00:11,400 --> 00:00:13,560 Speaker 1: think I'm on record in this episode even as saying 5 00:00:13,600 --> 00:00:16,560 Speaker 1: allergies don't tend to affect me, they beat me this 6 00:00:16,640 --> 00:00:18,919 Speaker 1: year and I've had a rough time with the pollen, 7 00:00:19,040 --> 00:00:21,920 Speaker 1: so uh kind of got me thinking about allergies again, 8 00:00:21,960 --> 00:00:24,239 Speaker 1: and I thought maybe you all could learn a little 9 00:00:24,280 --> 00:00:29,880 Speaker 1: something to enjoy. Welcome to Stuff you should know from 10 00:00:29,960 --> 00:00:38,720 Speaker 1: house stuff Works dot Com. Hey, and welcome to the podcast. 11 00:00:38,760 --> 00:00:42,800 Speaker 1: I'm Josh Clark, and there's Charlestovi, Chuck Bryant looking particularly 12 00:00:42,840 --> 00:00:46,279 Speaker 1: smart to day's glasses. Check someone with the beard, by 13 00:00:46,280 --> 00:00:49,320 Speaker 1: the way, that's right. Kind of bibles of mine after 14 00:00:49,400 --> 00:00:52,280 Speaker 1: making video content, having an entire season of a television 15 00:00:52,320 --> 00:00:54,320 Speaker 1: show that people still say, wait, I thought it was 16 00:00:54,360 --> 00:00:56,920 Speaker 1: the other one. Yeah, it's not like this is you know, 17 00:00:57,080 --> 00:00:59,960 Speaker 1: the radio days of nineteen forties when you really didn't 18 00:01:00,000 --> 00:01:02,440 Speaker 1: know what people look like like worst and Orsten Wells 19 00:01:02,520 --> 00:01:05,479 Speaker 1: is a baby face I used to bearded up back 20 00:01:05,480 --> 00:01:08,360 Speaker 1: in the day. Yeah, I think of him as like 21 00:01:08,440 --> 00:01:12,199 Speaker 1: the in Citizen Kane early on and he was clean 22 00:01:12,240 --> 00:01:17,440 Speaker 1: shaving baby face, right, yes, so what are you saying? 23 00:01:17,560 --> 00:01:23,400 Speaker 1: How's this like, Citizen Kane? It's not okay, good one, 24 00:01:23,520 --> 00:01:27,640 Speaker 1: thanks man, Um, how you doing. I'm good, A little 25 00:01:27,680 --> 00:01:30,640 Speaker 1: under the weather, but not because of allergies. You're sure. 26 00:01:30,800 --> 00:01:33,160 Speaker 1: Well it's funny you said that because Emily was like, 27 00:01:33,160 --> 00:01:35,680 Speaker 1: you know, you may have some allergies, but sometimes you 28 00:01:35,720 --> 00:01:38,319 Speaker 1: think you're getting sick and it could just be allergies. 29 00:01:38,520 --> 00:01:42,520 Speaker 1: It definitely could be. Yeah, well she's super allergic to 30 00:01:43,000 --> 00:01:46,080 Speaker 1: all sorts of stuff. Yeah, just really bad allergies, not 31 00:01:46,120 --> 00:01:50,080 Speaker 1: like food allergies, season yes, seasonal pollen, dust fight, brag 32 00:01:50,080 --> 00:01:53,920 Speaker 1: weed and all that stuff. Yeah. Venom. Yeah, and I 33 00:01:53,960 --> 00:01:56,440 Speaker 1: grew up. Yeah, I grew up with allergies. I think 34 00:01:56,440 --> 00:01:59,480 Speaker 1: I've mentioned this before, um, like asthma and all kinds 35 00:01:59,520 --> 00:02:02,080 Speaker 1: of stuff, And I just grew out of it because 36 00:02:02,120 --> 00:02:04,880 Speaker 1: that faith healer. Yeah, I guess so, right, I got 37 00:02:04,880 --> 00:02:07,040 Speaker 1: bit by that rattlesnake and everything was all good. Yeah. 38 00:02:07,160 --> 00:02:11,040 Speaker 1: Venom it works both ways, right, Actually it does because 39 00:02:11,040 --> 00:02:14,079 Speaker 1: there's anti venom. Remember didn't we do one on what's 40 00:02:14,080 --> 00:02:17,160 Speaker 1: the most venomous or poisonous all in the world? That 41 00:02:17,240 --> 00:02:19,799 Speaker 1: was a good one. It was the country of Australia. 42 00:02:20,480 --> 00:02:25,440 Speaker 1: It was it's a dangerous place. Well, Chuck, I specifically 43 00:02:25,440 --> 00:02:29,360 Speaker 1: remember one time when we were at work and you 44 00:02:29,400 --> 00:02:32,600 Speaker 1: were attacked by a bee and I had to deliver 45 00:02:32,880 --> 00:02:37,120 Speaker 1: an een shot to your thigh. Remember the whole gang 46 00:02:37,240 --> 00:02:39,320 Speaker 1: was there, the whole gang. They carted you off in 47 00:02:39,360 --> 00:02:42,160 Speaker 1: an ambulance. It was really kind of traumatic for us. 48 00:02:43,080 --> 00:02:45,280 Speaker 1: But I got my magnum p I played that day, 49 00:02:45,320 --> 00:02:48,240 Speaker 1: so it kind of everything balanced out. Every all's well, 50 00:02:48,280 --> 00:02:51,760 Speaker 1: that ends well. But what's mind boggling is that you 51 00:02:51,800 --> 00:02:55,680 Speaker 1: don't even have an allergy two bees. So like what 52 00:02:55,800 --> 00:02:58,280 Speaker 1: happened there, Well, that was just TV. It was a 53 00:02:58,320 --> 00:03:02,320 Speaker 1: TV show. Yeah, let me troubled distinguishing reality from fiction 54 00:03:02,360 --> 00:03:06,160 Speaker 1: these days, other people are too. Had you um had 55 00:03:06,160 --> 00:03:09,519 Speaker 1: to be allergy? Though, after reading this article you would 56 00:03:09,600 --> 00:03:11,680 Speaker 1: know what was going on. Yeah, And I think we 57 00:03:11,720 --> 00:03:13,800 Speaker 1: even covered that in the B podcast, didn't We We 58 00:03:13,880 --> 00:03:16,920 Speaker 1: covered like anaphylactic shock a little bit. But this is 59 00:03:16,960 --> 00:03:19,200 Speaker 1: like what we're about to talking about is allergies. The 60 00:03:19,960 --> 00:03:24,120 Speaker 1: cellular basis of what constitutes an allergy, how they're created, 61 00:03:24,160 --> 00:03:26,880 Speaker 1: where they come from. It's pretty cool. Yeah, I tried 62 00:03:26,880 --> 00:03:28,720 Speaker 1: to stump Emily this morning because I thought I was 63 00:03:28,760 --> 00:03:30,959 Speaker 1: being a smart guy. And even though she has bad allergies, also, 64 00:03:30,960 --> 00:03:32,519 Speaker 1: I could bet you don't even know what they really are. 65 00:03:32,840 --> 00:03:35,640 Speaker 1: Oh yeah, she's like, um, yeah, it's an overreaction from 66 00:03:35,640 --> 00:03:39,560 Speaker 1: your immune system to proceed invader, almost exactly like that, 67 00:03:39,600 --> 00:03:41,640 Speaker 1: And now I felt really stupid. It's like, oh to 68 00:03:41,880 --> 00:03:45,560 Speaker 1: perceived invader. She loved it. She's like called me smart 69 00:03:45,600 --> 00:03:51,080 Speaker 1: guy and like followed me around the house, brow beating me. Yeah. Um, 70 00:03:51,200 --> 00:03:53,520 Speaker 1: so she's absolutely right, though, I mean, an allergy is 71 00:03:53,560 --> 00:03:56,480 Speaker 1: basically a case of mistaken identity as far as your 72 00:03:56,480 --> 00:03:59,720 Speaker 1: immune system is concerned. You know, um, you've got all 73 00:03:59,760 --> 00:04:02,320 Speaker 1: sorts of foreign invaders coming at you all the time, 74 00:04:02,720 --> 00:04:04,800 Speaker 1: and we have an immune system to handle these things. 75 00:04:05,080 --> 00:04:07,080 Speaker 1: But every once in a while, and it depends, they 76 00:04:07,160 --> 00:04:12,880 Speaker 1: think probably that you are um, genetically unfulfilled if you 77 00:04:12,920 --> 00:04:16,720 Speaker 1: have allergies. Oh it's not a complete genetic code or something. Yeah, 78 00:04:16,800 --> 00:04:19,400 Speaker 1: Like you have a little bit of information missing. Your 79 00:04:19,480 --> 00:04:22,400 Speaker 1: immune system has a little bit of information missing. And 80 00:04:22,520 --> 00:04:25,520 Speaker 1: so for example that in the article they used the 81 00:04:25,600 --> 00:04:30,839 Speaker 1: example of um, like, uh, shrimp, You can eat shrimp 82 00:04:31,839 --> 00:04:34,080 Speaker 1: and there's maybe a protein attached to it that your 83 00:04:34,120 --> 00:04:36,960 Speaker 1: body is like did he eat this or where did 84 00:04:37,000 --> 00:04:39,599 Speaker 1: this come from? Or he being attacked by shrimp exactly, 85 00:04:40,080 --> 00:04:45,080 Speaker 1: And they think probably that all allergies are triggered by proteins. 86 00:04:45,120 --> 00:04:47,680 Speaker 1: But it's a case of mistaken identity. So let's talk 87 00:04:47,680 --> 00:04:50,560 Speaker 1: about this. Let's let's get into the immune system a 88 00:04:50,640 --> 00:04:54,920 Speaker 1: little bit. How how the immune system handles foreign invaders 89 00:04:55,160 --> 00:04:58,640 Speaker 1: perceived or otherwise. That's right. Uh, well, I guess we 90 00:04:58,720 --> 00:05:03,520 Speaker 1: could start with something called lymphocyte. And um, you've probably 91 00:05:03,560 --> 00:05:06,200 Speaker 1: heard of things like T cells and B cells. Those 92 00:05:06,200 --> 00:05:08,960 Speaker 1: are lymphocytes. Yeah, T cells are if that's how they 93 00:05:09,040 --> 00:05:11,320 Speaker 1: determine whether you have HIV. I believe like if your 94 00:05:11,320 --> 00:05:14,680 Speaker 1: T cell count is low because HIV is a it's 95 00:05:14,720 --> 00:05:19,600 Speaker 1: a an Immunoh. So they are both white blood cells 96 00:05:19,720 --> 00:05:23,279 Speaker 1: and they are really important to the immune system. Um, 97 00:05:23,360 --> 00:05:27,720 Speaker 1: but they make mistakes sometimes, right, And I love the 98 00:05:27,760 --> 00:05:31,040 Speaker 1: way this Who wrote this, by the way, Steve Beach, freelancer, 99 00:05:31,560 --> 00:05:33,640 Speaker 1: never heard of him. I thought he did a great 100 00:05:33,680 --> 00:05:37,560 Speaker 1: job though, because he likened the being T cells to 101 00:05:38,520 --> 00:05:41,680 Speaker 1: custom agents systoms agents just like they go anywhere they 102 00:05:41,680 --> 00:05:46,200 Speaker 1: want in your body and they investigate cells and basically 103 00:05:46,200 --> 00:05:48,920 Speaker 1: are like, let me see your papers where you going. 104 00:05:49,040 --> 00:05:51,200 Speaker 1: It's like, what's the purpose of your visit? It's like 105 00:05:51,240 --> 00:05:54,560 Speaker 1: arizona in your body. Yeah. Yeah, Like they show up 106 00:05:54,600 --> 00:05:57,600 Speaker 1: anywhere they can, Like you said, they can make it anywhere. 107 00:05:57,600 --> 00:06:00,640 Speaker 1: They can pass through membranes and blood vessels and just 108 00:06:00,680 --> 00:06:04,080 Speaker 1: pop up and they go, who are you lymph notes? Yeah, 109 00:06:04,240 --> 00:06:06,039 Speaker 1: very important for them to visit the lymph notes. It 110 00:06:06,160 --> 00:06:08,520 Speaker 1: is very important because that's where they go back and 111 00:06:08,560 --> 00:06:12,360 Speaker 1: start producing antibodies. Right, that's right. When they see something 112 00:06:12,720 --> 00:06:15,240 Speaker 1: and they discover a cell and they say, hold on 113 00:06:15,279 --> 00:06:19,960 Speaker 1: a minute, you'll pap us are not in order, then 114 00:06:20,160 --> 00:06:24,000 Speaker 1: there's trouble and they launched. Basically they start the attack 115 00:06:24,120 --> 00:06:29,240 Speaker 1: at that point. And we haven't quite figured this out. Um. Basically, 116 00:06:29,279 --> 00:06:33,919 Speaker 1: what happens when a B cell, especially encounters in a 117 00:06:34,000 --> 00:06:38,680 Speaker 1: foreign body, which is called an antigen because they generate antibodies, 118 00:06:38,720 --> 00:06:41,080 Speaker 1: they trigger the generation of antibodies in your body. In 119 00:06:41,120 --> 00:06:44,760 Speaker 1: your body, so that's where antigen comes from. Um. The 120 00:06:45,279 --> 00:06:49,560 Speaker 1: B cell basically takes down all of its data and 121 00:06:49,600 --> 00:06:52,440 Speaker 1: then goes back up into the lymph nodes, and that 122 00:06:52,680 --> 00:06:54,599 Speaker 1: that B cell, that white blood cell, turns into a 123 00:06:54,600 --> 00:06:58,440 Speaker 1: plasma cell and starts churning out antibodies that are specifically 124 00:06:58,480 --> 00:07:02,960 Speaker 1: tailored to counteract that antigen that for an invader that 125 00:07:03,000 --> 00:07:06,400 Speaker 1: it encountered. Right, and our body um our bodies have 126 00:07:06,480 --> 00:07:10,480 Speaker 1: five types of antibodies, and they're called immunoglobulens. I love 127 00:07:10,480 --> 00:07:12,360 Speaker 1: that word. It's tough to get out, but it's a 128 00:07:12,400 --> 00:07:14,800 Speaker 1: great word. Yeah. Uh, we'll call them I G s 129 00:07:15,000 --> 00:07:18,920 Speaker 1: and UM. I G E is the one that's responsible 130 00:07:19,000 --> 00:07:21,800 Speaker 1: for allergic reactions. Yeah. And the reason that that one 131 00:07:21,840 --> 00:07:24,280 Speaker 1: is responsible for allergic reactions as we understand them, is 132 00:07:24,320 --> 00:07:29,880 Speaker 1: because I G ease immunoglobulin ease. Yeah. Right. Um. They 133 00:07:29,880 --> 00:07:35,800 Speaker 1: attached to mast cells and uh baso fills and those 134 00:07:35,800 --> 00:07:38,360 Speaker 1: are two different types of UM cells. A mass cell 135 00:07:38,400 --> 00:07:41,440 Speaker 1: is found in a connective tissue and basi phil is 136 00:07:41,640 --> 00:07:44,280 Speaker 1: um a type of white blood cell. But they share 137 00:07:44,320 --> 00:07:47,640 Speaker 1: the commonality that both of them contain histamine. And when 138 00:07:47,680 --> 00:07:53,280 Speaker 1: they are hijacked by an I G e UM antibody, uh, 139 00:07:53,800 --> 00:07:58,120 Speaker 1: they basically become little ticking time bombs. So, so think 140 00:07:58,160 --> 00:08:00,920 Speaker 1: about this when you're when you come in contact with 141 00:08:00,960 --> 00:08:03,720 Speaker 1: an anogen and your body goes off, that white blood 142 00:08:03,720 --> 00:08:07,679 Speaker 1: cell goes off and starts producing antibodies. That first moment 143 00:08:07,720 --> 00:08:12,160 Speaker 1: of contact creates what's called the sensitizing exposure, right, Yeah, 144 00:08:12,160 --> 00:08:15,040 Speaker 1: and it's it's basically a mistake. It is in the 145 00:08:15,080 --> 00:08:17,600 Speaker 1: case of allergies, yeah, because I mean, like, there's nothing 146 00:08:17,640 --> 00:08:22,640 Speaker 1: inherently dangerous about ragweed pollen, and your body can handle 147 00:08:22,720 --> 00:08:27,840 Speaker 1: b venom and shellfish, right. But it's there's some protein 148 00:08:28,000 --> 00:08:30,560 Speaker 1: in each of those that certain people's bodies if they 149 00:08:30,560 --> 00:08:33,360 Speaker 1: don't have the genetic code for their white blood cells 150 00:08:33,400 --> 00:08:36,760 Speaker 1: to say, oh you pass, You're fine, then there's that 151 00:08:36,800 --> 00:08:39,880 Speaker 1: case of mistaken identity. Like you said, So, once you 152 00:08:39,880 --> 00:08:42,480 Speaker 1: have that sensitizing exposure, the first time your body comes 153 00:08:42,520 --> 00:08:45,040 Speaker 1: across this protein and there's that mistaken identity, it starts 154 00:08:45,040 --> 00:08:48,800 Speaker 1: producing antibodies, and those antibodies attached in the case of 155 00:08:48,840 --> 00:08:53,240 Speaker 1: I G S to um baza fills and mass cells, 156 00:08:53,400 --> 00:08:56,240 Speaker 1: and they start circulating throughout your body just waiting for 157 00:08:56,280 --> 00:08:58,640 Speaker 1: the next time it encounters that anigin that it's been 158 00:08:58,679 --> 00:09:03,680 Speaker 1: specifically designed to interact with. That's right, And what happens 159 00:09:03,720 --> 00:09:07,960 Speaker 1: then they say, hey, I know you, you're not supposed 160 00:09:08,000 --> 00:09:11,480 Speaker 1: to be here. I'm going to release something called histamine, 161 00:09:11,880 --> 00:09:14,319 Speaker 1: which is can be a great thing in your body 162 00:09:14,360 --> 00:09:17,720 Speaker 1: because that's what's gonna you know. That's basically your arsenal 163 00:09:17,800 --> 00:09:21,440 Speaker 1: fighting this this invader. But it can be a bad 164 00:09:21,480 --> 00:09:24,840 Speaker 1: thing too, um if too much of it is released, 165 00:09:24,840 --> 00:09:27,080 Speaker 1: as as we will see in a little while. Yeah. 166 00:09:27,160 --> 00:09:29,840 Speaker 1: So when in uh, when an and body and I 167 00:09:29,920 --> 00:09:35,160 Speaker 1: g E connects to an antigen um, it's already connected 168 00:09:35,200 --> 00:09:38,280 Speaker 1: to a mass seller basophil. Remember those things are loaded 169 00:09:38,320 --> 00:09:40,680 Speaker 1: with with histamine, so they're basically taking them along for 170 00:09:40,720 --> 00:09:43,280 Speaker 1: the party, right. Yeah, So when it connects it, it 171 00:09:43,440 --> 00:09:48,600 Speaker 1: sends a signal to something called um compliment proteins I believe, 172 00:09:49,240 --> 00:09:51,720 Speaker 1: and those compliment proteins come along and say, oh cool, 173 00:09:51,760 --> 00:09:54,240 Speaker 1: a chain reaction we can start to fulfill. And they 174 00:09:54,280 --> 00:09:56,800 Speaker 1: start locking on and locking on and locking on, and 175 00:09:56,840 --> 00:09:59,360 Speaker 1: once a certain amount of them have kind of locked 176 00:09:59,400 --> 00:10:05,760 Speaker 1: together along into this um antibody anergin mast cell, basophil 177 00:10:06,720 --> 00:10:10,880 Speaker 1: joint um, the mass cell or the basi phil goes 178 00:10:11,120 --> 00:10:14,200 Speaker 1: bluey and all of a sudden you have histamine floating 179 00:10:14,200 --> 00:10:18,800 Speaker 1: through your body. That's right. It basically destroys those original 180 00:10:18,880 --> 00:10:23,840 Speaker 1: cells such that the histamine is just released and unduly released. 181 00:10:23,880 --> 00:10:26,960 Speaker 1: And this is called the allergic cascade. This is what 182 00:10:27,000 --> 00:10:29,000 Speaker 1: we think of so you you may have come in 183 00:10:29,040 --> 00:10:33,520 Speaker 1: contact with shrimp and then ten days later you ate shrimp. 184 00:10:33,600 --> 00:10:36,559 Speaker 1: I I know I had an an allergic reaction shrimp. Um. 185 00:10:37,640 --> 00:10:42,360 Speaker 1: Oh yeah, okay, yeah, spoiler all right, UM. And it 186 00:10:42,440 --> 00:10:45,960 Speaker 1: takes maybe seven to ten days for that sensitizing exposure. 187 00:10:46,240 --> 00:10:48,520 Speaker 1: From that time to the next time, you could have 188 00:10:48,559 --> 00:10:50,400 Speaker 1: the allergic cascade, because that's how long it takes for 189 00:10:50,440 --> 00:10:53,600 Speaker 1: your body produced the antibodies. But when that that allergic 190 00:10:53,679 --> 00:10:56,920 Speaker 1: cascade is kicked off and the histamine is released, that's 191 00:10:56,920 --> 00:10:59,960 Speaker 1: when the symptoms that we associate with UM the type 192 00:11:00,040 --> 00:11:04,520 Speaker 1: of of allergy come about. So like if you inhale 193 00:11:04,600 --> 00:11:08,640 Speaker 1: it um, your mucous membranes are gonna flare up. You 194 00:11:08,679 --> 00:11:12,240 Speaker 1: might get hives. Hives which are basically like histamines caused 195 00:11:12,320 --> 00:11:15,360 Speaker 1: your blood vessels in the area to leak, which makes 196 00:11:15,360 --> 00:11:19,760 Speaker 1: it swell. That's a hive. Uh sneezing, wheezing all that. 197 00:11:19,800 --> 00:11:21,760 Speaker 1: I could wheeze right now if you want, if you 198 00:11:21,880 --> 00:11:23,760 Speaker 1: let me, but it would be really gross. Let's here, 199 00:11:24,200 --> 00:11:26,920 Speaker 1: I don't want to um because people would say, oh, man, chuck, 200 00:11:26,920 --> 00:11:31,880 Speaker 1: get to a sanitarium. But I'm sick. I don't have allergies. Sanitary. Yeah, 201 00:11:31,960 --> 00:11:38,000 Speaker 1: remember that. Yeah, like the Kellogg's thing. Yeah, sure, battle creek, Uh, nausea, diarrhea, 202 00:11:38,040 --> 00:11:41,200 Speaker 1: little vomiting. Maybe that's like you know, I think that's 203 00:11:41,240 --> 00:11:45,600 Speaker 1: the scale from least reaction to most. If you're vomiting, 204 00:11:46,000 --> 00:11:48,719 Speaker 1: then you've ingested something that you're really allergic to. Yeah. 205 00:11:48,800 --> 00:11:51,920 Speaker 1: You can become swollen usually like the part of your 206 00:11:51,960 --> 00:11:55,400 Speaker 1: body or the type of reaction you have, right like 207 00:11:55,440 --> 00:11:58,080 Speaker 1: where if you if your skin swells, if your arms swells, 208 00:11:58,840 --> 00:12:02,000 Speaker 1: you probably didn't inhale all learn just that it probably 209 00:12:02,200 --> 00:12:04,080 Speaker 1: came in contact with your skin, like a break in 210 00:12:04,120 --> 00:12:06,720 Speaker 1: your skin. Yeah. It depends on how you ingest it 211 00:12:06,800 --> 00:12:09,640 Speaker 1: and how your body reacts to it because it's different 212 00:12:09,640 --> 00:12:13,559 Speaker 1: for everyone, and severity obviously. But speaking of severity, it 213 00:12:13,600 --> 00:12:15,280 Speaker 1: can get really bad, which you talked about in the 214 00:12:15,280 --> 00:12:20,959 Speaker 1: B episode. Um, if this cascade, of this allergic cascade 215 00:12:21,320 --> 00:12:24,400 Speaker 1: UH is allowed to continue and you have enough of 216 00:12:24,440 --> 00:12:27,040 Speaker 1: a reaction to it, you have enough antibodies attached to 217 00:12:27,240 --> 00:12:29,120 Speaker 1: mass cells and bass it fills that a ton of 218 00:12:29,160 --> 00:12:31,960 Speaker 1: histamine is released, you can be in big trouble. You 219 00:12:31,960 --> 00:12:36,000 Speaker 1: can go into what's called anaphylactic shock. Yeah, and UH, 220 00:12:36,880 --> 00:12:39,800 Speaker 1: proceeding that you can have anaphylaxis, which is not quite 221 00:12:39,840 --> 00:12:42,960 Speaker 1: as bad. It's a it's a bad reaction, but it's 222 00:12:43,000 --> 00:12:45,200 Speaker 1: not the full blown shock. If you're in full blown 223 00:12:45,240 --> 00:12:50,240 Speaker 1: shock mode, then you could die easily and within minutes. 224 00:12:50,280 --> 00:12:52,760 Speaker 1: Even if you have let's say, like a peanut allergy 225 00:12:53,480 --> 00:12:55,880 Speaker 1: and you accidentally eat those peanuts. Unless you get that 226 00:12:56,000 --> 00:12:59,880 Speaker 1: injection of epinephrin that's gonna open those airways and restrict 227 00:12:59,880 --> 00:13:03,120 Speaker 1: the blood vessels back to their normal levels, then you 228 00:13:03,160 --> 00:13:05,439 Speaker 1: could be a goner, like really soon, right, And that's 229 00:13:05,440 --> 00:13:07,960 Speaker 1: called scary. That's called a systemic reaction where your whole 230 00:13:08,000 --> 00:13:11,320 Speaker 1: system is involved in this. And um, you're if you're 231 00:13:11,920 --> 00:13:16,560 Speaker 1: Since histamine dilates the blood vessels, your blood pressure can drop. Um. 232 00:13:16,600 --> 00:13:21,000 Speaker 1: It also causes swelling. Uh so like if your airways swollen, 233 00:13:21,280 --> 00:13:23,520 Speaker 1: that tends to close it off, which means it's tough 234 00:13:23,559 --> 00:13:25,560 Speaker 1: for you to breathe. Yeah, you could starve your brain 235 00:13:25,600 --> 00:13:29,600 Speaker 1: and kidneys of oxygen. Um and you know, oregon failure 236 00:13:29,600 --> 00:13:32,360 Speaker 1: can happen. And I think what they say, several hundred 237 00:13:32,360 --> 00:13:35,760 Speaker 1: people die in the United States alone each year. Yeah, 238 00:13:35,800 --> 00:13:38,240 Speaker 1: because we didn't cover this in the UM in the 239 00:13:38,280 --> 00:13:41,960 Speaker 1: TV episode about bees where I delivered that from Penn 240 00:13:42,000 --> 00:13:45,240 Speaker 1: and saved your life, if you'll remember. I do remember. Um. 241 00:13:45,280 --> 00:13:48,600 Speaker 1: But apparently the effects of the epic pen last ten 242 00:13:48,640 --> 00:13:51,360 Speaker 1: to twenty minutes. Yeah, I didn't realize it was that short. Yeah, 243 00:13:51,400 --> 00:13:53,640 Speaker 1: so we should have had you outfitted with like a 244 00:13:53,640 --> 00:13:55,520 Speaker 1: whole belt of those things. I thought you were just 245 00:13:55,559 --> 00:13:58,480 Speaker 1: good to go once you have the EpiPen shot. Apparently 246 00:13:58,480 --> 00:14:00,880 Speaker 1: not so. I think it's just like, hey, let's stave 247 00:14:00,920 --> 00:14:02,800 Speaker 1: off death until we can get you to a hospital. 248 00:14:02,840 --> 00:14:04,840 Speaker 1: I think so too. But you have to do it 249 00:14:04,880 --> 00:14:08,040 Speaker 1: early enough so that it can it can have the 250 00:14:08,080 --> 00:14:11,960 Speaker 1: effect of counteracting that's allergic reaction. Uh. And you you, 251 00:14:12,200 --> 00:14:14,320 Speaker 1: if it's longer than ten to twenty minutes to get 252 00:14:14,360 --> 00:14:16,199 Speaker 1: to the hospital, you should probably have more in one pen. 253 00:14:16,880 --> 00:14:19,720 Speaker 1: But even if you've survived, your brain and your kidneys 254 00:14:19,720 --> 00:14:22,320 Speaker 1: being starved of oxygen, you can suffer long term damage 255 00:14:22,360 --> 00:14:24,720 Speaker 1: from going into anaphylactic shock. Yeah. I would be a 256 00:14:24,840 --> 00:14:28,840 Speaker 1: freak if I had this possibility existing in my life. 257 00:14:29,040 --> 00:14:31,560 Speaker 1: I would have an EpiPen in my car and my 258 00:14:32,120 --> 00:14:34,400 Speaker 1: you know, in each room of my house. I would 259 00:14:34,400 --> 00:14:36,800 Speaker 1: not take any chances. And what about like a peanut 260 00:14:36,800 --> 00:14:38,760 Speaker 1: allergy too, It's gotta be so easy to come in 261 00:14:38,840 --> 00:14:42,000 Speaker 1: contact with that. Yeah. Well, and we've mentioned that time 262 00:14:42,040 --> 00:14:44,320 Speaker 1: on the plane when they said you can't even open 263 00:14:44,360 --> 00:14:46,200 Speaker 1: peanuts on this flight, and we had people right in 264 00:14:46,240 --> 00:14:49,280 Speaker 1: they were like, yeah, dude, that's a that could seriously happen, right, 265 00:14:49,280 --> 00:14:51,720 Speaker 1: And I understand that. What's crazy to me is like, 266 00:14:51,760 --> 00:14:53,760 Speaker 1: if you fly Delta, they'll give you a peanuts all 267 00:14:53,840 --> 00:14:57,000 Speaker 1: day long. Well not if someone says that they're allergic. 268 00:14:57,440 --> 00:14:59,560 Speaker 1: That's the point. Yeah, I guess. So this is a 269 00:14:59,560 --> 00:15:01,680 Speaker 1: delta for And they said, I'm sorry, everyone, no peanuts 270 00:15:01,680 --> 00:15:05,080 Speaker 1: today because what's the delt. I thought was towel E 271 00:15:05,880 --> 00:15:09,360 Speaker 1: is allergic peanuts. Yeah, Everybody's like, oh God, I want 272 00:15:09,400 --> 00:15:11,680 Speaker 1: my peanuts. I hate Yeah, I guess I'll just eat 273 00:15:12,040 --> 00:15:20,000 Speaker 1: Press pretzels and Biscott cookies. Dirt dirt. Okay, So all right, 274 00:15:20,080 --> 00:15:23,120 Speaker 1: let's say you have allergies, or let's say you think 275 00:15:23,160 --> 00:15:26,400 Speaker 1: you have allergies and you want to go in and 276 00:15:26,880 --> 00:15:29,280 Speaker 1: find out for sure. There are a couple of ways 277 00:15:29,400 --> 00:15:34,800 Speaker 1: that they can that they can test this out, honey, Yeah, 278 00:15:34,960 --> 00:15:38,720 Speaker 1: and and run into a beehive. Uh no, you would 279 00:15:38,840 --> 00:15:41,680 Speaker 1: do what's called the scratch test. And I've never had 280 00:15:41,680 --> 00:15:44,400 Speaker 1: one of these. Emily's had one, and she also does immunotherapy, 281 00:15:44,440 --> 00:15:47,720 Speaker 1: which we'll get to. But they apply a diluted extract 282 00:15:47,840 --> 00:15:51,920 Speaker 1: of you know, different kinds of allergens to like your 283 00:15:51,920 --> 00:15:54,080 Speaker 1: back or your arm, and then they scratch you with 284 00:15:54,200 --> 00:15:57,280 Speaker 1: a needle and they see what happens, and if it 285 00:15:57,320 --> 00:16:00,200 Speaker 1: becomes swollen and red, then they say, you know, I 286 00:16:00,280 --> 00:16:03,520 Speaker 1: think you're allergic to ragweed because we just put some 287 00:16:03,600 --> 00:16:05,520 Speaker 1: on your body and scratched it. They can also do 288 00:16:05,600 --> 00:16:09,800 Speaker 1: blood tests and search for specific antigens. Yeah, that's better 289 00:16:09,840 --> 00:16:12,480 Speaker 1: for kids, I think, yeah, because it can cause a 290 00:16:12,480 --> 00:16:15,600 Speaker 1: sensitizing event in a kid if you expose them to it. 291 00:16:15,600 --> 00:16:19,800 Speaker 1: Because everybody knows their genes are just stupid. Yeah, they're 292 00:16:19,880 --> 00:16:24,840 Speaker 1: like a very um susceptible to influence. I guess, which 293 00:16:24,840 --> 00:16:27,520 Speaker 1: is weird to me. So here's the thing. Does that 294 00:16:27,560 --> 00:16:32,240 Speaker 1: mean that it's impossible to die from your first beasting? 295 00:16:32,920 --> 00:16:35,880 Speaker 1: That at what is possible or impossible? Because if there 296 00:16:35,880 --> 00:16:38,840 Speaker 1: has to be a sensitizing event, how would you come 297 00:16:38,840 --> 00:16:41,400 Speaker 1: in contact with the venom other than to be stung? 298 00:16:41,720 --> 00:16:44,360 Speaker 1: How would you become sensitized? I was looking all over 299 00:16:44,400 --> 00:16:46,600 Speaker 1: the internet, sor and I think One of the things 300 00:16:46,640 --> 00:16:48,880 Speaker 1: that kind of found well doing additional research for this 301 00:16:48,960 --> 00:16:51,440 Speaker 1: episode is that we have a pretty good idea of 302 00:16:51,440 --> 00:16:55,400 Speaker 1: how allergies work, but it's definitely not complete yet. Yeah, 303 00:16:55,240 --> 00:16:57,200 Speaker 1: I mean when you're on the cellular level, I'm sure 304 00:16:57,240 --> 00:17:00,600 Speaker 1: there are still some mysteries to be had. But they say, 305 00:17:00,600 --> 00:17:03,480 Speaker 1: it's like, because one of your questions was, how do 306 00:17:03,560 --> 00:17:07,720 Speaker 1: they identify that for an invader? And I was happy 307 00:17:07,760 --> 00:17:10,320 Speaker 1: to just say they identify for an invader, right, and 308 00:17:10,320 --> 00:17:12,440 Speaker 1: how do they how do they take down its information 309 00:17:12,480 --> 00:17:14,639 Speaker 1: and then go back to the to the lymph node 310 00:17:14,640 --> 00:17:17,720 Speaker 1: and start producing an animboo. They had a pin and 311 00:17:17,720 --> 00:17:20,639 Speaker 1: pad and they had a little golf cart. They did 312 00:17:20,680 --> 00:17:23,200 Speaker 1: a police sketch. Yeah, that's the way I set um. 313 00:17:23,240 --> 00:17:26,160 Speaker 1: So you've got scratched therapy, blood tests, they both work, 314 00:17:26,240 --> 00:17:30,640 Speaker 1: they're okay. Um. And then if you if they say 315 00:17:30,680 --> 00:17:34,280 Speaker 1: you know what you are you're allergic to somethings Y 316 00:17:34,280 --> 00:17:36,879 Speaker 1: and Z. There's basically three things they recommend. The first 317 00:17:36,960 --> 00:17:40,440 Speaker 1: is to avoid that thing whatever it is, sure and 318 00:17:40,480 --> 00:17:42,880 Speaker 1: if that's shell fish or peanuts, then you're pretty good 319 00:17:42,880 --> 00:17:45,080 Speaker 1: shape because that's pretty easy to avoid in most cases. 320 00:17:45,760 --> 00:17:47,959 Speaker 1: You would think, have you ever had a shrimp allergy. 321 00:17:48,080 --> 00:17:52,000 Speaker 1: Shrimp is pretty delicious, No, but it's it's easier to 322 00:17:52,040 --> 00:17:55,439 Speaker 1: avoid than pollen, let's say, because pollen's everywhere, especially here 323 00:17:55,440 --> 00:17:57,400 Speaker 1: in the South. So if you're allergic to pollen, there's 324 00:17:57,440 --> 00:17:59,719 Speaker 1: no avoiding it. I mean there's cars that all the 325 00:17:59,720 --> 00:18:01,960 Speaker 1: car is in the spring in the South, or yellow. 326 00:18:02,280 --> 00:18:06,880 Speaker 1: Every car's painting the streets run yellow. Literally. Yeah. Yeah, Um, 327 00:18:06,960 --> 00:18:10,879 Speaker 1: so you would take medication accorded coasteroid. You might walk 328 00:18:10,920 --> 00:18:12,680 Speaker 1: around with an F and f rompen depending on what 329 00:18:12,840 --> 00:18:16,479 Speaker 1: you are allergic to. Um, you know that kind of thing. 330 00:18:16,760 --> 00:18:18,879 Speaker 1: And then the third one is what you said Emily 331 00:18:19,000 --> 00:18:20,680 Speaker 1: was doing and what I've done before too, which is 332 00:18:20,720 --> 00:18:25,480 Speaker 1: immunotherapy done this I think? So, I mean I undertook 333 00:18:25,520 --> 00:18:29,440 Speaker 1: the process of immunotherapy by myself and it seems to 334 00:18:29,520 --> 00:18:31,840 Speaker 1: have worked. I was about to say, did a doctor 335 00:18:31,880 --> 00:18:34,040 Speaker 1: give you injections at point in your life? Tell me 336 00:18:34,040 --> 00:18:37,320 Speaker 1: about Emily's experience. Well, she she does the standard immunotherapy 337 00:18:37,359 --> 00:18:40,600 Speaker 1: where she goes into to get her allergy shots once 338 00:18:41,000 --> 00:18:44,840 Speaker 1: a month, I think, And um, they start you out 339 00:18:44,960 --> 00:18:48,080 Speaker 1: on a on a low uh dose that's like a 340 00:18:48,400 --> 00:18:53,239 Speaker 1: basically a weak delusion of these antigens. And they they 341 00:18:53,400 --> 00:18:56,000 Speaker 1: injected in her body and just build that up over 342 00:18:56,119 --> 00:18:59,359 Speaker 1: time to increase her her immune response I guess right. 343 00:18:59,520 --> 00:19:01,480 Speaker 1: And then over time, so this is what they think 344 00:19:01,640 --> 00:19:08,160 Speaker 1: happens over time. Either the body possibly gets it's genetic 345 00:19:08,280 --> 00:19:11,440 Speaker 1: information filled in enough so that it's it's like, oh, 346 00:19:12,160 --> 00:19:16,240 Speaker 1: was my face red because this wasn't actually a foreign invader, 347 00:19:16,320 --> 00:19:21,399 Speaker 1: It's just a shrimp protein UM. And or they believe 348 00:19:21,520 --> 00:19:26,160 Speaker 1: that another UH and a body I g G, which 349 00:19:26,240 --> 00:19:29,280 Speaker 1: acts as kind of like a blocking antibody that prevents 350 00:19:29,640 --> 00:19:33,240 Speaker 1: an allergic reaction, UM starts to build up as a 351 00:19:33,359 --> 00:19:36,960 Speaker 1: as a result of immunotherapy. We should say, I think 352 00:19:37,080 --> 00:19:40,800 Speaker 1: immunotherapy is still fairly controversial, is it. I believe so, 353 00:19:41,160 --> 00:19:44,359 Speaker 1: because it's introducing, you know, a potentially dangerous thing into 354 00:19:44,520 --> 00:19:47,880 Speaker 1: a human being. And it's not like if you ask 355 00:19:48,000 --> 00:19:53,240 Speaker 1: somebody if honey as a good immunotherapy, Logically it should 356 00:19:53,320 --> 00:19:56,000 Speaker 1: make sense. If you use local honey, very very local honey, 357 00:19:56,400 --> 00:19:58,920 Speaker 1: it's going to contain some of the same pollen um 358 00:19:59,359 --> 00:20:02,000 Speaker 1: that you're supposed to that you're allergic to in it, 359 00:20:02,359 --> 00:20:04,240 Speaker 1: and so when you eat it, when you ingested, it's 360 00:20:04,280 --> 00:20:06,400 Speaker 1: like taking that low level and it should be doing 361 00:20:06,440 --> 00:20:09,359 Speaker 1: the same thing as that, you know, taking injections from 362 00:20:09,400 --> 00:20:13,159 Speaker 1: the doctor, but it's more delicious and it takes a 363 00:20:13,240 --> 00:20:15,600 Speaker 1: long time. At we's been at it for she was 364 00:20:15,640 --> 00:20:18,359 Speaker 1: at it for a couple of years without virtually no 365 00:20:18,920 --> 00:20:22,000 Speaker 1: uh success, right, so it takes Has it been helping 366 00:20:22,040 --> 00:20:25,040 Speaker 1: though at all? I think so, because she still has 367 00:20:25,080 --> 00:20:28,200 Speaker 1: bad allergies, but they used to be way worse. But 368 00:20:28,320 --> 00:20:30,520 Speaker 1: she's been on these shots now for like, I mean, 369 00:20:30,560 --> 00:20:31,560 Speaker 1: she did it when she was a kid and then 370 00:20:31,600 --> 00:20:33,639 Speaker 1: she's been on it again for like five years. Probably 371 00:20:34,400 --> 00:20:37,640 Speaker 1: it's been a while. So I've I've had one serious. 372 00:20:38,000 --> 00:20:42,480 Speaker 1: It wasn't even serious, but it was my distinct allergic reaction. 373 00:20:42,920 --> 00:20:45,440 Speaker 1: And it was shrimp once and I ate it and 374 00:20:45,600 --> 00:20:47,280 Speaker 1: you mean, just like why are you red? And like 375 00:20:47,400 --> 00:20:49,280 Speaker 1: what are those red dots all over you? What's going on? 376 00:20:49,760 --> 00:20:53,280 Speaker 1: And uh, I figured out I was. I was having 377 00:20:53,320 --> 00:20:56,119 Speaker 1: an allergic reaction to shrimp. So I've never had before, right, 378 00:20:56,680 --> 00:20:58,760 Speaker 1: and I love shrimp. And I tried it the next day, 379 00:20:58,800 --> 00:21:00,480 Speaker 1: tried a little by a shrimp kind of had a 380 00:21:00,560 --> 00:21:02,960 Speaker 1: similar reaction. So I was like, something's going on here. 381 00:21:03,760 --> 00:21:05,760 Speaker 1: So I decided that I was going to get myself 382 00:21:05,880 --> 00:21:13,880 Speaker 1: over my shrimp allergy. Right. Have you ever had shrimp chips? Uh? Yes, 383 00:21:14,240 --> 00:21:17,840 Speaker 1: They're delicious. They're delicious. They're like little kind of potato 384 00:21:17,960 --> 00:21:20,520 Speaker 1: chip French fries with their shrimp flavor because they have 385 00:21:20,680 --> 00:21:23,600 Speaker 1: shrimp dust on them, like sexual powdered shrimp shrimp dust. 386 00:21:24,000 --> 00:21:27,840 Speaker 1: So I started like very eating little amounts of shrimp chip, 387 00:21:27,960 --> 00:21:30,000 Speaker 1: and then over the over time I would eat more 388 00:21:30,240 --> 00:21:32,560 Speaker 1: whole bags of them at a time, you know. Um, 389 00:21:32,720 --> 00:21:34,240 Speaker 1: and then finally I get to the point where I 390 00:21:34,280 --> 00:21:36,680 Speaker 1: could eat shrimping it. I don't know if that really 391 00:21:36,760 --> 00:21:39,560 Speaker 1: cured me or if that was just a fluke, like 392 00:21:39,720 --> 00:21:42,040 Speaker 1: maybe that shrimp was just a local type of shrimp 393 00:21:42,119 --> 00:21:46,040 Speaker 1: and Carolinas or something like. But um, that's that's my 394 00:21:46,400 --> 00:21:50,000 Speaker 1: immunotherapy story. Well, you can eat shrimp now like Gangbusters, 395 00:21:50,040 --> 00:21:53,320 Speaker 1: So yeah, and I do, do you really? Yeah, whenever 396 00:21:53,400 --> 00:21:55,840 Speaker 1: I can. I like shrimp. I'm trying to make up 397 00:21:55,880 --> 00:21:58,000 Speaker 1: for lost time because I spent like three years, two 398 00:21:58,080 --> 00:22:01,600 Speaker 1: years without eating shrimp. So be where prawns and Trump 399 00:22:01,720 --> 00:22:06,680 Speaker 1: of the world, gosh, number eat you live? Will you know? 400 00:22:07,119 --> 00:22:10,640 Speaker 1: Okay that's gross. No, it's not people do that. Um, 401 00:22:11,600 --> 00:22:14,399 Speaker 1: I guess that's it. Yeah, that is allergies. And I 402 00:22:14,480 --> 00:22:16,840 Speaker 1: bet the reason I quizzed Emily is because I think 403 00:22:16,840 --> 00:22:19,640 Speaker 1: a lot of people who have allergies don't even understand 404 00:22:19,760 --> 00:22:24,040 Speaker 1: the core concepts. And uh yeah, hopefully now you do that. 405 00:22:24,160 --> 00:22:26,760 Speaker 1: It's a case of mistaken identity. It's so awesome. Yeah, 406 00:22:27,560 --> 00:22:33,440 Speaker 1: and your your DNA is dumb or incomplete. Okay, UM, 407 00:22:34,240 --> 00:22:36,159 Speaker 1: if you like this, you should go check out how 408 00:22:36,280 --> 00:22:38,399 Speaker 1: allergies work. You can type them in the search bar 409 00:22:38,680 --> 00:22:40,959 Speaker 1: how stuff works dot com. You can also look up 410 00:22:41,080 --> 00:22:44,280 Speaker 1: another article I wrote about using honey for immunotherapy. That's 411 00:22:44,320 --> 00:22:49,399 Speaker 1: pretty interesting. Um. Probably like honey allergies maybe would be 412 00:22:49,480 --> 00:22:52,040 Speaker 1: too good words of putting the search bar for that one. Um, 413 00:22:52,200 --> 00:22:54,600 Speaker 1: and I said the search bar twice, which means we're 414 00:22:54,600 --> 00:22:58,120 Speaker 1: gonna have to listener males. Huh just one o. Well, first, 415 00:22:58,160 --> 00:22:59,560 Speaker 1: before we do that, how about a word from our 416 00:22:59,560 --> 00:23:05,480 Speaker 1: sponsor time for listener mal Okay, I'm gonna call this 417 00:23:06,119 --> 00:23:10,760 Speaker 1: in the name of the fire guys. I just listened 418 00:23:10,760 --> 00:23:15,240 Speaker 1: to your cast on stunt men stunt women, let's just 419 00:23:15,280 --> 00:23:17,480 Speaker 1: say stunt people, and I was reminded of his story. 420 00:23:17,520 --> 00:23:19,000 Speaker 1: I thought you might like to hear my dad as 421 00:23:19,000 --> 00:23:20,639 Speaker 1: an actor and way back in the nineties, he was 422 00:23:20,680 --> 00:23:22,600 Speaker 1: in a film called In the Name of the Father, 423 00:23:22,800 --> 00:23:25,640 Speaker 1: Remember that, Oh yeah, with Daniel day Lewis. Right, great 424 00:23:25,680 --> 00:23:29,840 Speaker 1: movie is that his dad? Um? He said? It stars 425 00:23:29,880 --> 00:23:34,800 Speaker 1: Abraham Lincoln or Daniel day Lewis. In the film he 426 00:23:34,880 --> 00:23:36,840 Speaker 1: played and this is one of my favorite like movies 427 00:23:36,880 --> 00:23:38,760 Speaker 1: from that year. By the way, it's about the I 428 00:23:38,920 --> 00:23:41,320 Speaker 1: r A, wasn't it. Yeah? It was about like a 429 00:23:41,560 --> 00:23:47,440 Speaker 1: wrongfully imprisoned um group of friends basically that they suspected 430 00:23:47,480 --> 00:23:49,840 Speaker 1: as being like bombers. I don't want to give ways 431 00:23:49,840 --> 00:23:54,320 Speaker 1: too much, okay, but there is a prison in the film. 432 00:23:54,400 --> 00:23:56,520 Speaker 1: He played a prison guard who gets set on fire 433 00:23:56,920 --> 00:23:59,560 Speaker 1: by some pretty nasty inmates. So I guess there's a 434 00:23:59,600 --> 00:24:02,919 Speaker 1: fire too in the Guard. In the Guard, what happens 435 00:24:03,000 --> 00:24:05,080 Speaker 1: next served as a warning for any actor who decides 436 00:24:05,080 --> 00:24:07,760 Speaker 1: their up for performing their own stunts. The director decide 437 00:24:07,760 --> 00:24:10,159 Speaker 1: of my dad could do some flailing and running with 438 00:24:10,280 --> 00:24:13,280 Speaker 1: his arms on fire, and that a stunt professional would 439 00:24:13,320 --> 00:24:16,920 Speaker 1: do the more intense full body fire shots. We like 440 00:24:17,080 --> 00:24:20,040 Speaker 1: we said in the Stunt Person podcast, like the fire thing. 441 00:24:20,080 --> 00:24:22,480 Speaker 1: You're always running, you going, what what do you doing? 442 00:24:22,560 --> 00:24:24,320 Speaker 1: You're on fire? Do you stand there? Like? Can someone 443 00:24:24,400 --> 00:24:27,040 Speaker 1: put me out. Some people do Buddhist monks just sit there. 444 00:24:27,280 --> 00:24:31,640 Speaker 1: Well that, yeah, that's different. I'm ready on the one. 445 00:24:32,359 --> 00:24:35,680 Speaker 1: They wrapped up his arms, covered them in jelly, and 446 00:24:35,800 --> 00:24:38,159 Speaker 1: set them ablaze. But what my dad had failed to 447 00:24:38,200 --> 00:24:40,560 Speaker 1: realize is that the stuntmen do not wait for anyone 448 00:24:40,640 --> 00:24:43,280 Speaker 1: to say action. As a result, he just stood there 449 00:24:43,320 --> 00:24:45,720 Speaker 1: on fire, waiting for someone to say he could go, 450 00:24:46,280 --> 00:24:48,720 Speaker 1: while it's getting hotter and hotter with each passing second. 451 00:24:49,440 --> 00:24:54,360 Speaker 1: Fortunately the director eventually realized what was happening and hastily 452 00:24:54,520 --> 00:24:58,080 Speaker 1: yelled go. But by this time my dad was way 453 00:24:58,119 --> 00:25:00,400 Speaker 1: too hot and just kind of side stuff up into 454 00:25:00,440 --> 00:25:03,200 Speaker 1: the shot, waving his arms like a half baked ballerina. 455 00:25:03,880 --> 00:25:05,840 Speaker 1: If you watch the scene carefully you can actually see 456 00:25:05,920 --> 00:25:09,080 Speaker 1: the shots. He was really on fire, and by the 457 00:25:09,200 --> 00:25:11,760 Speaker 1: genuine fear and panic in his eyes, I hope you 458 00:25:11,800 --> 00:25:14,600 Speaker 1: guys carry on making knees for as long as humanly possible. 459 00:25:15,080 --> 00:25:19,720 Speaker 1: That is Freddie Turner from Oxford, England. Nice. And I 460 00:25:19,760 --> 00:25:24,920 Speaker 1: guess Freddie or Mollie didn't Saycy Jr. Was on fire? 461 00:25:25,680 --> 00:25:27,840 Speaker 1: And I think Jim Sheridan was a director of that movie, 462 00:25:27,880 --> 00:25:30,480 Speaker 1: if I remember correctly, So Jim Sherdan was the one 463 00:25:30,520 --> 00:25:34,360 Speaker 1: who say go oh, yeah, that's a pretty great listener mail, Yeah, 464 00:25:34,359 --> 00:25:37,000 Speaker 1: that's a good one. Was the dude's name, Freddie, Freddie 465 00:25:37,040 --> 00:25:40,159 Speaker 1: Freddie pretty turner in Oxford Englin. Cool Um. Well, if 466 00:25:40,240 --> 00:25:43,320 Speaker 1: you have a great story associated with something we've talked about, 467 00:25:43,680 --> 00:25:45,760 Speaker 1: as always, we want to hear it, You can tweak 468 00:25:45,840 --> 00:25:47,679 Speaker 1: to us at s Y s K podcast. You can 469 00:25:47,760 --> 00:25:50,080 Speaker 1: join us on Facebook dot com slash stuff you Should Know. 470 00:25:50,600 --> 00:25:53,399 Speaker 1: You can send us an email to Stuff Podcast at 471 00:25:53,440 --> 00:25:56,480 Speaker 1: Discovery dot com and check out our website Stuff you 472 00:25:56,520 --> 00:26:06,360 Speaker 1: Should Know dot com. For more on this and thousands 473 00:26:06,400 --> 00:26:14,159 Speaker 1: of other topics, visit how Stuff Works dot com. M