WEBVTT - Pharma Gave Us a Vaccine in Record Time

0:00:00.040 --> 0:00:02.520
<v Speaker 1>I'm Carol Mass, Sir. The Bloomberg Business Week cover story

0:00:02.560 --> 0:00:05.360
<v Speaker 1>this week is about how so much went terribly wrong

0:00:05.400 --> 0:00:08.160
<v Speaker 1>this year, but at least one thing went right. Fiser

0:00:08.240 --> 0:00:11.240
<v Speaker 1>and Maderna both got their vaccines across the finish line,

0:00:11.600 --> 0:00:15.000
<v Speaker 1>baring surprises. By spring, tens of millions of Americans will

0:00:15.000 --> 0:00:17.840
<v Speaker 1>have receive shots. By summer, if there will be hundreds

0:00:17.880 --> 0:00:21.720
<v Speaker 1>of millions, more lives will be saved, economies will recover.

0:00:22.239 --> 0:00:25.520
<v Speaker 1>It's an achievement worth celebrating, a shining example of people

0:00:25.600 --> 0:00:29.160
<v Speaker 1>understanding what their job really is than doing it. It's

0:00:29.200 --> 0:00:31.920
<v Speaker 1>also a story that highlights just how badly the US

0:00:31.960 --> 0:00:35.720
<v Speaker 1>screwed up almost everywhere else. This episode is brought to

0:00:35.760 --> 0:00:40.479
<v Speaker 1>you by Principal Financial Group, combining actionable insights with specialized

0:00:40.560 --> 0:00:44.320
<v Speaker 1>solutions to help you meet your investment goals. Get to

0:00:44.360 --> 0:00:50.320
<v Speaker 1>know us at Principal dot Com. Business at its best.

0:00:51.440 --> 0:00:54.720
<v Speaker 1>With a big hand from the government, pharmaceutical companies delivered

0:00:54.760 --> 0:00:58.680
<v Speaker 1>the vaccine that the world desperately needed. Here's how something

0:00:59.640 --> 0:01:06.640
<v Speaker 1>went right for a change by Drew Armstrong. At the

0:01:06.720 --> 0:01:11.480
<v Speaker 1>end of before the coronavirus pandemic started, the two best

0:01:11.520 --> 0:01:14.680
<v Speaker 1>known faces of the pharmaceutical business were the imprisoned Martin

0:01:14.720 --> 0:01:19.560
<v Speaker 1>Screlly and the lawsuit laden opioid makers at Purdue Pharma.

0:01:19.880 --> 0:01:22.200
<v Speaker 1>The rest of the industry was perhaps best known for

0:01:22.240 --> 0:01:26.119
<v Speaker 1>the skyrocketing prices of its medicines. In a gallop pole

0:01:26.240 --> 0:01:29.680
<v Speaker 1>of the public's view of various business sectors, pharma was

0:01:29.760 --> 0:01:33.920
<v Speaker 1>ranked at the bottom, behind the oil industry, advertising in

0:01:33.959 --> 0:01:38.720
<v Speaker 1>public relations, and lawyers. Who'd have guessed that a year

0:01:38.800 --> 0:01:41.800
<v Speaker 1>later pharma would be getting credit for saving the world

0:01:42.520 --> 0:01:45.720
<v Speaker 1>from cruise lines to meet backers. Business will have plenty

0:01:45.760 --> 0:01:48.560
<v Speaker 1>to answer for in its handling of the pandemic, but

0:01:48.680 --> 0:01:52.480
<v Speaker 1>this part of it worked. The COVID nineteen vaccines developed

0:01:52.480 --> 0:01:56.280
<v Speaker 1>by the drug industry in partnership with governments will almost

0:01:56.320 --> 0:01:59.840
<v Speaker 1>certainly prevent hundreds of thousands of American deaths and millions

0:02:00.120 --> 0:02:03.680
<v Speaker 1>or around the world. They will revive trillions of dollars

0:02:03.720 --> 0:02:08.679
<v Speaker 1>in economic activity, let grandparents see grandchildren, and finally bring

0:02:08.680 --> 0:02:11.200
<v Speaker 1>an end to a year that has sing it together

0:02:11.320 --> 0:02:13.880
<v Speaker 1>one last time as the ball drops over an empty

0:02:13.919 --> 0:02:18.800
<v Speaker 1>Times Square. Really sucked. In a time when almost everything

0:02:18.840 --> 0:02:22.120
<v Speaker 1>else went wrong, the vaccine effort was something that went

0:02:22.400 --> 0:02:27.399
<v Speaker 1>mostly right. The quest started in early January, before most

0:02:27.400 --> 0:02:29.800
<v Speaker 1>people in the US and Europe were even thinking about

0:02:29.840 --> 0:02:34.240
<v Speaker 1>a pandemic. The biotechnology company Moderna had downloaded the genetic

0:02:34.280 --> 0:02:38.120
<v Speaker 1>code for the novel coronavirus from researchers in China. Within

0:02:38.160 --> 0:02:41.400
<v Speaker 1>a few days, scientists there had developed a vaccine with

0:02:41.480 --> 0:02:44.720
<v Speaker 1>the U S National Institute of Allergy and Infectious Diseases,

0:02:45.160 --> 0:02:48.760
<v Speaker 1>the research agency led by Anthony Fauci. By mid March,

0:02:49.120 --> 0:02:53.680
<v Speaker 1>they'd started a clinical trial. Feiser announced its own plans

0:02:53.680 --> 0:02:56.640
<v Speaker 1>around the same time. A year and a half before,

0:02:57.200 --> 0:03:00.000
<v Speaker 1>it had signed a deal with a German biotech company,

0:03:00.000 --> 0:03:03.799
<v Speaker 1>io in Tech, that has similar messenger RNA technology to

0:03:03.880 --> 0:03:08.359
<v Speaker 1>Maderna's that could, in theory, rapidly assemble and test vaccines.

0:03:09.200 --> 0:03:12.160
<v Speaker 1>Like Maderna, the company's thought the technology could make it

0:03:12.160 --> 0:03:15.760
<v Speaker 1>possible to quickly turn around a prototype. The world hasn't

0:03:15.760 --> 0:03:18.280
<v Speaker 1>seen an emergency like this in one hundred years, says

0:03:18.280 --> 0:03:21.480
<v Speaker 1>Stephen Joffey, the interim chairman of the Department of Medical

0:03:21.520 --> 0:03:24.680
<v Speaker 1>Ethics and Health Policy at the Perlman School of Medicine

0:03:24.680 --> 0:03:27.520
<v Speaker 1>at the University of Pennsylvania. We are lucky in the

0:03:27.560 --> 0:03:31.480
<v Speaker 1>sense that the science was there. Other crucial pieces fell

0:03:31.480 --> 0:03:35.040
<v Speaker 1>into place behind the scenes. For years, the research chiefs

0:03:35.080 --> 0:03:38.040
<v Speaker 1>of the top pharmaceutical companies have had an annual gathering

0:03:38.080 --> 0:03:40.920
<v Speaker 1>to talk about ways to speed up their work. As

0:03:40.960 --> 0:03:44.520
<v Speaker 1>the COVID crisis got worse, about twenty drug companies started

0:03:44.520 --> 0:03:47.160
<v Speaker 1>a working group with the National Institutes of Health and

0:03:47.240 --> 0:03:50.520
<v Speaker 1>other government agencies, meeting every other week to look at

0:03:50.520 --> 0:03:55.160
<v Speaker 1>potential therapies and coordinate clinical trials, says Paul Staffles, the

0:03:55.200 --> 0:03:58.240
<v Speaker 1>chief scientific officer at Johnson and Johnson, which has a

0:03:58.320 --> 0:04:01.240
<v Speaker 1>large scale COVID vaccine trial at expected to produce results

0:04:01.280 --> 0:04:05.120
<v Speaker 1>in January. Those efforts would eventually be folded into what's

0:04:05.160 --> 0:04:09.360
<v Speaker 1>now known as the Trump administration's Operation Warp Speed program.

0:04:09.560 --> 0:04:12.400
<v Speaker 1>Warp Speed was revealed at the end of April, when

0:04:12.400 --> 0:04:16.200
<v Speaker 1>the pandemic had killed close to sixty thousand Americans. The

0:04:16.279 --> 0:04:19.040
<v Speaker 1>goal was to develop and produce enough shots to inoculate

0:04:19.080 --> 0:04:23.040
<v Speaker 1>three hundred million Americans before the new year. Some companies,

0:04:23.080 --> 0:04:26.320
<v Speaker 1>including Maderna and J and J would get direct funding

0:04:26.360 --> 0:04:29.440
<v Speaker 1>for their efforts. Weiser got an agreement from the government

0:04:29.440 --> 0:04:33.279
<v Speaker 1>to buy the vaccine it produced if it worked. Crucially,

0:04:33.480 --> 0:04:37.920
<v Speaker 1>the government was shouldering some risk financing the advanced production

0:04:38.000 --> 0:04:41.480
<v Speaker 1>of the experimental vaccines while clinical trials were still going on.

0:04:42.279 --> 0:04:44.960
<v Speaker 1>The most risk averse people on Earth and the riskiest

0:04:44.960 --> 0:04:48.080
<v Speaker 1>business on Earth is how US Health and Human Services

0:04:48.080 --> 0:04:52.479
<v Speaker 1>Secretary Alex Asar describes the drug industry. Probably the most

0:04:52.560 --> 0:04:55.400
<v Speaker 1>common words said in a farmer company are how do

0:04:55.480 --> 0:04:59.880
<v Speaker 1>you d risk this? Asar, whose department helped over sea warps,

0:05:00.560 --> 0:05:03.280
<v Speaker 1>says he understood how tricky a bet on vaccines can

0:05:03.279 --> 0:05:06.200
<v Speaker 1>be for a business. These companies are looking at making

0:05:06.200 --> 0:05:09.960
<v Speaker 1>the multibillion dollar investments in R and D and manufacturing capacity,

0:05:10.200 --> 0:05:13.960
<v Speaker 1>he says, and they had just been through Zekea stars.

0:05:14.240 --> 0:05:18.000
<v Speaker 1>They've been through mers viruses for which the pharmaceutical industry

0:05:18.040 --> 0:05:21.080
<v Speaker 1>investigated vaccines that never saw the outside of a clinical

0:05:21.120 --> 0:05:25.880
<v Speaker 1>trial before those outbreaks dissipated or were squashed. The government's

0:05:25.920 --> 0:05:28.760
<v Speaker 1>backing let smaller players get in the game and take

0:05:28.800 --> 0:05:33.400
<v Speaker 1>some riskier technologies forward. Smaller companies such as Moderna, don't

0:05:33.480 --> 0:05:36.080
<v Speaker 1>have the resources to do this on their own, Joffey

0:05:36.160 --> 0:05:40.360
<v Speaker 1>says of large scale clinical trials. Fiser, despite its corporate

0:05:40.360 --> 0:05:43.920
<v Speaker 1>reputation as a rival consuming Shark, said it would offer

0:05:44.000 --> 0:05:48.160
<v Speaker 1>up any excess manufacturing capacity it might have, potentially producing

0:05:48.160 --> 0:05:52.480
<v Speaker 1>competitors vaccines. But even a company of J and J's size.

0:05:52.920 --> 0:05:56.680
<v Speaker 1>It reported fifteen point one billion dollars in profits last year.

0:05:57.200 --> 0:06:01.000
<v Speaker 1>Needs incentives to rapidly start up a costlyvaccine development and

0:06:01.040 --> 0:06:05.760
<v Speaker 1>testing effort. Staffel says pharma companies could reasonably predict that

0:06:05.880 --> 0:06:08.719
<v Speaker 1>COVID would be bad and that a vaccine would have

0:06:08.720 --> 0:06:12.279
<v Speaker 1>a market, But to mobilize a billion, maybe two billion

0:06:12.360 --> 0:06:14.760
<v Speaker 1>dollars to start manufacturing and do the R and D

0:06:15.200 --> 0:06:19.200
<v Speaker 1>is daunting. He says, Well, we are big companies. Nobody

0:06:19.240 --> 0:06:21.520
<v Speaker 1>can free up two billion dollars in their profit and

0:06:21.600 --> 0:06:26.279
<v Speaker 1>law statement overnight. Moderna, Astra, Zeneca and other vaccine developers

0:06:26.279 --> 0:06:29.480
<v Speaker 1>who joined warp Speed agreed to use similar structures for

0:06:29.520 --> 0:06:32.520
<v Speaker 1>their clinical trials so they could easily be compared with

0:06:32.560 --> 0:06:34.679
<v Speaker 1>one another, and so it would be easier to see

0:06:34.720 --> 0:06:38.560
<v Speaker 1>clear winners. The government also put together a single safety

0:06:38.560 --> 0:06:42.320
<v Speaker 1>board to oversee them, which pins Jaffey sits on. It

0:06:42.360 --> 0:06:45.320
<v Speaker 1>was an unusual approach, but it let the safety monitors

0:06:45.360 --> 0:06:47.960
<v Speaker 1>look for worrying side effects or problems that could show

0:06:48.040 --> 0:06:51.839
<v Speaker 1>up in more than one trial. In usual circumstances, drug

0:06:51.880 --> 0:06:55.680
<v Speaker 1>makers might design their experiments to show advantages over competitors

0:06:55.800 --> 0:06:59.479
<v Speaker 1>or dodge a potential head to head analysis. Big Fiser

0:06:59.640 --> 0:07:03.239
<v Speaker 1>and any Moderna both got their vaccines across the finish line.

0:07:03.839 --> 0:07:06.520
<v Speaker 1>The shots cleared in December have been shipped out to

0:07:06.560 --> 0:07:10.560
<v Speaker 1>states and are now going into people's arms. Barring surprises,

0:07:10.680 --> 0:07:14.400
<v Speaker 1>By spring, tens of millions of Americans will have gotten them.

0:07:14.400 --> 0:07:17.600
<v Speaker 1>By summer, hundreds of millions more will have It's an

0:07:17.640 --> 0:07:21.760
<v Speaker 1>achievement worth celebrating, a shining example of people understanding what

0:07:21.800 --> 0:07:25.200
<v Speaker 1>their job really is then doing it. And it's not

0:07:25.240 --> 0:07:28.520
<v Speaker 1>a story with a single hero. It's one about government

0:07:28.560 --> 0:07:32.880
<v Speaker 1>scientists and private sector researchers. The trial volunteers who put

0:07:32.920 --> 0:07:36.320
<v Speaker 1>their bodies on the line, the doctors running the trials,

0:07:36.720 --> 0:07:39.640
<v Speaker 1>the FedEx and UPS workers making sure the vaccine is

0:07:39.640 --> 0:07:43.960
<v Speaker 1>delivered during a pandemic winter, the nurses donning PPE to

0:07:44.040 --> 0:07:47.480
<v Speaker 1>administer the shots, down to the first person being vaccinated

0:07:47.560 --> 0:07:51.760
<v Speaker 1>after the FDA's authorization go through the chain. And that's

0:07:51.760 --> 0:07:57.600
<v Speaker 1>who made this happen. But it's also a story that

0:07:57.680 --> 0:08:01.360
<v Speaker 1>highlights just how badly the US screwed up almost everything

0:08:01.400 --> 0:08:04.800
<v Speaker 1>else to do with controlling the pandemic. The nation had

0:08:04.960 --> 0:08:09.040
<v Speaker 1>every asset needed to curb the virus, the world's best scientists,

0:08:09.600 --> 0:08:14.360
<v Speaker 1>the biggest collection of biotechnology and pharma companies, a powerful government,

0:08:14.720 --> 0:08:18.720
<v Speaker 1>and well established public health institutions. The US even had

0:08:18.800 --> 0:08:23.560
<v Speaker 1>unlimited financing. Perhaps the one other thing policymakers got right

0:08:23.960 --> 0:08:26.120
<v Speaker 1>is that they pumped enough money into the system to

0:08:26.200 --> 0:08:29.600
<v Speaker 1>keep the economy alive. But even then, Congress was slow

0:08:29.640 --> 0:08:33.520
<v Speaker 1>to strike a second relief deal, and Americans still ended

0:08:33.600 --> 0:08:38.440
<v Speaker 1>up with a badly contained, deadly outbreak. Schools have gone remote,

0:08:39.000 --> 0:08:42.760
<v Speaker 1>lots of restaurants will never reopen. Chances are you know

0:08:42.920 --> 0:08:45.880
<v Speaker 1>somebody who was sick enough to be hospitalized or to

0:08:46.000 --> 0:08:50.360
<v Speaker 1>have died. Michael Mina, an assistant professor of epidemiology at

0:08:50.360 --> 0:08:53.559
<v Speaker 1>the Harvard TH H. Chan School of Public Health, believes

0:08:53.600 --> 0:08:57.240
<v Speaker 1>that cheap, plentiful, rapid tests long ago could have done

0:08:57.240 --> 0:08:59.600
<v Speaker 1>more to stop the pandemic than just about anything else

0:08:59.600 --> 0:09:02.160
<v Speaker 1>we've done on over the past few months. While watching

0:09:02.240 --> 0:09:05.679
<v Speaker 1>cases and debts stack up and hoping for a vaccine,

0:09:06.480 --> 0:09:08.400
<v Speaker 1>the only way to deal with the virus like this

0:09:08.480 --> 0:09:12.360
<v Speaker 1>appropriately is to try and identify people who are infectious.

0:09:12.400 --> 0:09:16.959
<v Speaker 1>He says he's helped develop an inexpensive, mostly accurate test

0:09:17.040 --> 0:09:19.640
<v Speaker 1>with rapid results that can be done on a strip

0:09:19.679 --> 0:09:23.079
<v Speaker 1>of paper. It's not as accurate as the diagnostic tests

0:09:23.080 --> 0:09:25.559
<v Speaker 1>you have to wait hours in line for and often

0:09:25.720 --> 0:09:28.439
<v Speaker 1>days to get a result back from. But it costs

0:09:28.480 --> 0:09:31.440
<v Speaker 1>pretty much nothing and is easy to make. We make

0:09:31.480 --> 0:09:34.439
<v Speaker 1>more bags of doritos than I'm asking for, he says,

0:09:34.480 --> 0:09:37.840
<v Speaker 1>of the number of tests needed. These are paper strips

0:09:37.880 --> 0:09:40.760
<v Speaker 1>that get cut from one big piece of paper. His

0:09:40.880 --> 0:09:43.600
<v Speaker 1>idea is that if you test like crazy, you can

0:09:43.640 --> 0:09:46.280
<v Speaker 1>find enough cases to tell people who are infectious not

0:09:46.360 --> 0:09:48.760
<v Speaker 1>to be out and about, and you halt a huge

0:09:48.760 --> 0:09:51.840
<v Speaker 1>amount of transmission. There are people who aren't wearing a

0:09:51.880 --> 0:09:55.439
<v Speaker 1>mask because of politics or whatever, Mina says, but they

0:09:55.440 --> 0:09:57.280
<v Speaker 1>may still not want to get their eighty year old

0:09:57.320 --> 0:10:00.440
<v Speaker 1>mom sick at Sunday dinner. He's pushed the idea to

0:10:00.480 --> 0:10:03.120
<v Speaker 1>anyone who will listen, but it would need regulators to

0:10:03.120 --> 0:10:06.360
<v Speaker 1>sign off and has never gotten off the ground. So

0:10:06.480 --> 0:10:09.920
<v Speaker 1>where was the warp speed for testing? Fauci, who's been

0:10:09.920 --> 0:10:12.640
<v Speaker 1>the face of the US response to the outbreak, or

0:10:12.679 --> 0:10:14.760
<v Speaker 1>at least the face of what it could have looked like,

0:10:15.360 --> 0:10:17.920
<v Speaker 1>said at a December ninth event at Harvard's School of

0:10:17.960 --> 0:10:20.320
<v Speaker 1>Public Health, that is not as if a program of

0:10:20.360 --> 0:10:23.760
<v Speaker 1>mass cheap testing would have been impossible to achieve. We

0:10:23.880 --> 0:10:26.839
<v Speaker 1>have done things infinitely more complicated than that. He said,

0:10:27.280 --> 0:10:31.000
<v Speaker 1>we have the technology, we can do it, which, when

0:10:31.000 --> 0:10:34.320
<v Speaker 1>you think about it, brings up more questions. Where was

0:10:34.360 --> 0:10:38.359
<v Speaker 1>the warp speed for contact tracing, for public health measures,

0:10:38.400 --> 0:10:42.079
<v Speaker 1>for data, for making sure health care workers had protective gear.

0:10:42.679 --> 0:10:45.760
<v Speaker 1>Where was the warp speed for keeping open businesses, churches,

0:10:45.760 --> 0:10:49.400
<v Speaker 1>and schools? For everything that went wrong? Where was that

0:10:49.520 --> 0:10:52.880
<v Speaker 1>combination of leadership and industry and money that could have

0:10:52.960 --> 0:10:56.719
<v Speaker 1>made it go right. While we've been marveling rightly at

0:10:56.720 --> 0:10:59.680
<v Speaker 1>the science that's made a vaccine possible, most of that

0:10:59.760 --> 0:11:03.480
<v Speaker 1>other stuff never got going at the same level. HHS

0:11:03.559 --> 0:11:06.960
<v Speaker 1>Secretary Asar says there was a national strategy for much

0:11:06.960 --> 0:11:10.040
<v Speaker 1>of this. It just wasn't as visible as warp speed.

0:11:10.840 --> 0:11:13.520
<v Speaker 1>But we're still facing a tough winter even with large

0:11:13.520 --> 0:11:17.800
<v Speaker 1>scale vaccination efforts on the horizon. Tests are more common now,

0:11:18.120 --> 0:11:21.120
<v Speaker 1>but hardly plentiful, at least not in the volume you'd

0:11:21.120 --> 0:11:24.240
<v Speaker 1>need to truly use them for a broad, constant public

0:11:24.240 --> 0:11:27.240
<v Speaker 1>health surveillance, the kind that would allow people on mass

0:11:27.280 --> 0:11:30.400
<v Speaker 1>to go to school or work, travel on airplanes, or

0:11:30.440 --> 0:11:34.199
<v Speaker 1>attend concerts or sporting events. In the New York City

0:11:34.240 --> 0:11:37.120
<v Speaker 1>suburb where I live, my wife and I spent days

0:11:37.200 --> 0:11:39.480
<v Speaker 1>trying to book a just to be sure COVID test

0:11:39.840 --> 0:11:43.199
<v Speaker 1>before we headed south to visit relatives for Christmas. As

0:11:43.240 --> 0:11:46.120
<v Speaker 1>I'm filing this to my editor, we're barreling down the

0:11:46.120 --> 0:11:48.720
<v Speaker 1>interstate with plans to eat food out of a cooler

0:11:49.160 --> 0:11:51.880
<v Speaker 1>p on the side of the road, and brave fourteen

0:11:51.960 --> 0:11:55.800
<v Speaker 1>hours in a midsize suv with two small children, one

0:11:55.840 --> 0:11:59.360
<v Speaker 1>of whom is disastrously vomit prone, all to preserve the

0:11:59.400 --> 0:12:02.280
<v Speaker 1>little bubble of isolation we've kept up ahead of the trip.

0:12:03.200 --> 0:12:06.080
<v Speaker 1>Even the uncomplicated things have been hard for much of

0:12:06.080 --> 0:12:09.200
<v Speaker 1>the country. Not wearing a mask is seen as a

0:12:09.200 --> 0:12:13.480
<v Speaker 1>political act by a significant portion of the population, unhelped

0:12:13.480 --> 0:12:16.520
<v Speaker 1>by a mixed message from government leaders, some of whom

0:12:16.559 --> 0:12:20.719
<v Speaker 1>have suggested that basically masks or for losers. We love

0:12:20.800 --> 0:12:23.600
<v Speaker 1>to inject ourselves with stuff, but when it comes to

0:12:23.679 --> 0:12:27.079
<v Speaker 1>simple messaging about health, doing something that would help people,

0:12:27.280 --> 0:12:30.679
<v Speaker 1>we hate it. Mina says, we are very willing to

0:12:30.679 --> 0:12:33.360
<v Speaker 1>mop up messes, but we have no willingness to stop

0:12:33.400 --> 0:12:36.840
<v Speaker 1>them before they occur. There is one more opportunity to

0:12:36.880 --> 0:12:39.920
<v Speaker 1>get a big thing right. The US gets credit for

0:12:39.960 --> 0:12:43.240
<v Speaker 1>having pushed the development of the vaccines. Now it has

0:12:43.280 --> 0:12:46.480
<v Speaker 1>to make sure people take them. First. The government has

0:12:46.480 --> 0:12:49.720
<v Speaker 1>to guarantee there's enough vaccine. That was a key part

0:12:49.760 --> 0:12:53.080
<v Speaker 1>of the goal of WARP speed. Since the program started,

0:12:53.160 --> 0:12:55.840
<v Speaker 1>the US has signed deals for enough shots to cover

0:12:55.920 --> 0:12:59.120
<v Speaker 1>five hundred and five million people, with the option to

0:12:59.160 --> 0:13:02.160
<v Speaker 1>buy more, but it has only enough from Fizer so

0:13:02.280 --> 0:13:06.560
<v Speaker 1>far for fifty million, and from Moderna for one hundred million.

0:13:07.240 --> 0:13:10.520
<v Speaker 1>Other vaccines it's made deals for, such as Astrasenica's and

0:13:10.600 --> 0:13:13.960
<v Speaker 1>JAY and Jay's, are still in development. There are growing

0:13:14.040 --> 0:13:17.959
<v Speaker 1>concerns that the US, after leading development of vaccines, may

0:13:17.960 --> 0:13:20.720
<v Speaker 1>not get them as fast as it had hoped. Instead

0:13:20.760 --> 0:13:23.400
<v Speaker 1>of three hundred million covered by the end of twenty twenty,

0:13:23.840 --> 0:13:26.600
<v Speaker 1>the US is now aiming to supply vaccine for twenty

0:13:26.640 --> 0:13:29.120
<v Speaker 1>million people by the end of December and getting to

0:13:29.200 --> 0:13:31.599
<v Speaker 1>a total of one hundred million by the end of February.

0:13:32.080 --> 0:13:34.920
<v Speaker 1>Vaccinating all of America now looks more like an end

0:13:34.960 --> 0:13:38.840
<v Speaker 1>of twenty twenty one goal. Even if there is enough vaccine,

0:13:38.840 --> 0:13:41.199
<v Speaker 1>of course, people have to be willing to take it.

0:13:41.679 --> 0:13:44.600
<v Speaker 1>If we have a ninety five percent effective vaccine and

0:13:44.720 --> 0:13:47.200
<v Speaker 1>only forty percent to fifty percent of the people in

0:13:47.280 --> 0:13:50.280
<v Speaker 1>society get vaccinated, It's going to take quite a while

0:13:50.360 --> 0:13:52.600
<v Speaker 1>to get to that blanket of herd immunity that's going

0:13:52.640 --> 0:13:58.800
<v Speaker 1>to protect us, Bauchi said at the Harvard event. Early

0:13:58.880 --> 0:14:01.800
<v Speaker 1>on in the development of the vaccines, there was debate

0:14:01.840 --> 0:14:05.040
<v Speaker 1>about whether to run what are known as challenge trials,

0:14:05.240 --> 0:14:08.880
<v Speaker 1>in these healthy volunteers get an experimental vaccine and are

0:14:08.920 --> 0:14:13.559
<v Speaker 1>deliberately exposed. It's an ethical razor's edge. Is it moral

0:14:13.679 --> 0:14:15.960
<v Speaker 1>to give somebody a virus you know, kills a small

0:14:16.040 --> 0:14:19.240
<v Speaker 1>percentage of patients with their best defense being a vaccine

0:14:19.240 --> 0:14:22.880
<v Speaker 1>that isn't known to work. Because there weren't COVID therapies

0:14:22.920 --> 0:14:26.480
<v Speaker 1>that could cure an infected patient, researchers passed on the

0:14:26.520 --> 0:14:31.040
<v Speaker 1>idea it wasn't worth the chance that someone could die. Instead,

0:14:31.160 --> 0:14:34.400
<v Speaker 1>the vaccine trials signed up tens of thousands of volunteers,

0:14:35.000 --> 0:14:37.600
<v Speaker 1>split into those who got the real shot and those

0:14:37.640 --> 0:14:40.520
<v Speaker 1>who got a placebo. To find out if the vaccine

0:14:40.560 --> 0:14:43.040
<v Speaker 1>was effective, they had to go back out into the

0:14:43.040 --> 0:14:45.400
<v Speaker 1>real world and bump into the virus on their own.

0:14:46.200 --> 0:14:49.480
<v Speaker 1>The idea with these large trials, the gold standard for

0:14:49.560 --> 0:14:52.760
<v Speaker 1>testing of vaccines efficacy and safety is that if the

0:14:52.880 --> 0:14:56.720
<v Speaker 1>vaccine works. COVID cases rapidly accumulate in the group that

0:14:56.800 --> 0:14:59.560
<v Speaker 1>got the placebo, but not in those who got the

0:14:59.600 --> 0:15:02.720
<v Speaker 1>real thing. Get enough cases and you can perform a

0:15:02.760 --> 0:15:06.960
<v Speaker 1>statistical analysis of exactly how effective the vaccine is. But

0:15:07.040 --> 0:15:10.040
<v Speaker 1>if there isn't enough virus circulating, few in the trial

0:15:10.120 --> 0:15:15.080
<v Speaker 1>get infected and results take longer. Over the summer, Visors

0:15:15.080 --> 0:15:18.320
<v Speaker 1>and Maderna's trials went into lulls as the pandemic waned.

0:15:18.880 --> 0:15:22.560
<v Speaker 1>Then in the fall, cases exploded. Millions of infections were

0:15:22.560 --> 0:15:25.680
<v Speaker 1>tallied around the country, and thousands of people died, and

0:15:25.720 --> 0:15:29.320
<v Speaker 1>the results started pouring in on the trials. Jay and

0:15:29.400 --> 0:15:31.680
<v Speaker 1>j said in December it would shrink the size of

0:15:31.680 --> 0:15:34.880
<v Speaker 1>its sixty thou person trial because the cases were coming

0:15:34.880 --> 0:15:38.520
<v Speaker 1>in so fast. The US, because of its failure to

0:15:38.560 --> 0:15:42.760
<v Speaker 1>control the pandemic, had essentially created one big challenge trial.

0:15:43.560 --> 0:15:45.840
<v Speaker 1>There is an irony and a situation that we all

0:15:45.880 --> 0:15:49.400
<v Speaker 1>hoped wouldn't have occurred. US Food and Drug Administration Commissioner

0:15:49.480 --> 0:15:53.239
<v Speaker 1>Stephen Hans says the number of cases did help expedite

0:15:53.240 --> 0:15:57.040
<v Speaker 1>the performance of clinical trials both here and abroad. That

0:15:57.080 --> 0:15:59.760
<v Speaker 1>did help us get to this point, But I think

0:16:00.080 --> 0:16:02.480
<v Speaker 1>of us would have wanted it to be that way.

0:16:02.880 --> 0:16:06.960
<v Speaker 1>That's the contradiction of the USS vaccine success. The government

0:16:07.000 --> 0:16:10.040
<v Speaker 1>and scientists, all working together, came up with a shot

0:16:10.120 --> 0:16:12.840
<v Speaker 1>to save the world, and then they were able to

0:16:12.880 --> 0:16:15.960
<v Speaker 1>prove so quickly that it worked only because those same

0:16:15.960 --> 0:16:22.240
<v Speaker 1>institutions couldn't save us from ourselves. With Robert Langreth, and

0:16:22.360 --> 0:16:25.000
<v Speaker 1>that is the Bloomberg Business Week cover story this week.

0:16:25.080 --> 0:16:28.160
<v Speaker 1>Check out more stories in the magazine on newsstands, online

0:16:28.200 --> 0:16:31.240
<v Speaker 1>at Bloomberg dot com and on the Bloomberg And be

0:16:31.240 --> 0:16:33.920
<v Speaker 1>sure to check out Bloomberg Business Week Daily on Bloomberg

0:16:34.000 --> 0:16:36.760
<v Speaker 1>Radio Monday through Friday, starting at two pm Wall Street Time,

0:16:37.240 --> 0:16:39.720
<v Speaker 1>also on our podcast feed at Bloomberg dot com and

0:16:40.160 --> 0:16:43.160
<v Speaker 1>on YouTube search Bloomberg Global News. I'm Carol Masser.