Speaker 1: Have you ever thought about how incredibly complex I spit is.
Speaker 1: It may only be water, but just aliva isn't simple.
Speaker 1: That remaining one percent holds incredibly meaningful information that could
Speaker 1: change everything. And I'm not just talking about your family
Speaker 1: treat Hi. I'm Barret to day Thurston. And on this
Speaker 1: season of Spit and I Heart Radio podcast with twenty
Speaker 1: three and Me, we explore how DNA isn't just about ancestry,
Speaker 1: it can also be key to understanding your health. Hello, Hello,
Speaker 1: and welcome back to another episode of Spit. Today we've
Speaker 1: got the one and only host of crime Stories, Nancy Grace.
Speaker 1: Nancy's taking a break from true crime to get to
Speaker 1: the bottom of an entirely different investigation her twenty three
Speaker 1: and Me Test reports. You might know Nancy as one
Speaker 1: of the fiercest legal analysts around, but she's also a
Speaker 1: proud mother of twins. Well, Nancy has covered some of
Speaker 1: the most famous and infamous cases in American true crime.
Speaker 1: She's also been known to share the fears and triumphs
Speaker 1: of motherhood with her listeners. So when Nancy and her
Speaker 1: family recently took a twenty three me test, she just
Speaker 1: had to let her listeners in on the journey, Nancy
Speaker 1: sits down with a panel of experts to get a
Speaker 1: better understanding of her family's reports and the role genetics
Speaker 1: play in their health. And connecting all the dots, she
Speaker 1: explores the science behind the test and looks to show
Speaker 1: listeners how the information contained in twenty three and me
Speaker 1: reports can empower you on the journey to a healthier life.
Speaker 1: Let's listen. In twenty three and me, you'd have to
Speaker 1: be living under a rock in a cave in a
Speaker 1: far away distantly and not to know what three and
Speaker 1: me is. It's ancestry testing. You find out where you're from,
Speaker 1: who you are so to speak, uh, chromosomely genetically that is,
Speaker 1: can that discovery unlock secrets the secrets of your genetic
Speaker 1: makeup that can help you lead healthier and I believe
Speaker 1: happier life. We hear stories about genetic tracing that you
Speaker 1: you find distant relatives, You find out your family tree
Speaker 1: goes all the way back to Anglo Saxon times. But
Speaker 1: how can it help me into here? And now I'm
Speaker 1: raising two twins they just turn fifteen. Let me wash
Speaker 1: my mouth out with soap. I can't believe they're fifteen.
Speaker 1: Can I learn anything from this genetic Uh? Let me
Speaker 1: say genetic makeup, genetic identity, genetic composite that will help
Speaker 1: my twins and me and my husband David and my
Speaker 1: mother Elizabeth live a longer, healthier life. I'mancy Grace and
Speaker 1: we are talking about twenty three and me with me
Speaker 1: an all star panel to make sense of all of this.
Speaker 1: If you're a LA person like me, I I'm just
Speaker 1: a j D. But I know nothing about genetic counseling.
Speaker 1: What does it mean? Joining me up an incredible host
Speaker 1: of yes, But I want to go first to Stacy
Speaker 1: debt Wiler. She is a license certified genetic counselor with
Speaker 1: twenty three and me, Stacy, thank you so much for
Speaker 1: being with us. Thank you here? What is in a
Speaker 1: nutshall remember? This is twenty three? And me for dummy's
Speaker 1: what is twenty three? And me? Hey, guys, by the way,
Speaker 1: I took the test, Go ahead tell me Stacy. It's
Speaker 1: a lot right. Um. So I think you you kind
Speaker 1: of mentioned what people first thing about is ancestry. But
Speaker 1: what I really get excited about it the hall. And
Speaker 1: there is a lot of information that you can find
Speaker 1: out from a little bit of spit which we're able
Speaker 1: to get DNA from, so there's information about your own Wait,
Speaker 1: did you say a little bit of spit? Because we
Speaker 1: have to spit and spit and spit. I mean I'm
Speaker 1: used to quiminal cases, Stacy, where you get a genetic
Speaker 1: marker and identity, and like this is mina skill amount
Speaker 1: of I don't blood saliva. Why did we have to
Speaker 1: spit so much? Yeah, that's why we fall the spit party. Um,
Speaker 1: I didn't think about it like that. I don't let
Speaker 1: to Alisa take this one a little bit, um, just
Speaker 1: because there's you know, you need to get enough DNA
Speaker 1: from that spit in order to be able to give
Speaker 1: you all these insights. Um, who's over six five? Okay,
Speaker 1: I'll go to Alisa with me is a Lisa Lehman,
Speaker 1: Senior manager and product science at twenty three and me
Speaker 1: and you can find everybody at medical dot twenty three
Speaker 1: and me dot com and it's and spelled out twenty
Speaker 1: three and me dot com atly soa welcome to you
Speaker 1: and Stacy. Why so much spit? You know you're a
Speaker 1: pH d and a senior manager. I feel kind of
Speaker 1: wrong asking you why did I have to spit so much?
Speaker 1: But why did I have to spit so much? Oh?
Speaker 1: Thank you for having me? And why do you have
Speaker 1: to sit so much? As the best question I think
Speaker 1: to ask, I'd love I'd love answering questions like this. Um.
Speaker 1: Like Stacy said, right, what we're trying to do is
Speaker 1: get your d NA um the easiest way possible. Right.
Speaker 1: We don't want people to have to go give us
Speaker 1: a blood sample, so spit very easy to get. But
Speaker 1: what we're doing is we're trying to get the d
Speaker 1: N A that's in almost every cell in your body,
Speaker 1: including the cells inside your cheeks. So when you spit
Speaker 1: and spit and spit, what's coming along for the ride
Speaker 1: is some of those cheek cells um from from your mouth.
Speaker 1: And what we're trying to do is make sure that
Speaker 1: we're going to get enough of those cells so we
Speaker 1: get enough DNA to make sure that when we run
Speaker 1: and analyze that DNA extracted from the cells, when we
Speaker 1: try and figure out your a's and seas and teas
Speaker 1: and gees from your DNA, that we have enough so
Speaker 1: you don't have to do it again. What are a's
Speaker 1: and seas and Jason T So your DNA you can
Speaker 1: think of as a code that is there to um
Speaker 1: explain how to you know what? Alsa lame and just
Speaker 1: stop right there. My son who is a star in
Speaker 1: robotics and science, and he keeps talking about coding, and
Speaker 1: I keep acting like I know what he's talking about.
Speaker 1: What are you talking about? So when I'm talking about
Speaker 1: the genetic code, it is more like you know codes
Speaker 1: during World War Two where you are trying there's information,
Speaker 1: but it is written in a way that you know
Speaker 1: you need to be able to decode it to understand it.
Speaker 1: So your DNA is like that. Okay, now I understand.
Speaker 1: Now I understand with me to new friends Stacy Entwiler
Speaker 1: and Alsa Lehman from twenty three and me and who
Speaker 1: longtime friends Karen Start joining us were now psychologists joining
Speaker 1: us out of Manhattan. You can find her at karen
Speaker 1: Start dot com. That's Karen with a C. And Dr
Speaker 1: Michelle dupre, my longtime colleague joining us out of South Carolina,
Speaker 1: forensic pathologist, medical examiner, author of multiple books. Dr Dupree, now,
Speaker 1: what about this a regular role? PhD just told me
Speaker 1: something you've never told me. I've never heard the phrase
Speaker 1: cheek seals have you heard the phrase cheek sales, Jackie. Yeah,
Speaker 1: you've never mentioned that. Dupre no. I always say epithelial sales,
Speaker 1: and you crashed down on me for using such a
Speaker 1: technical term. Yeah, do so. The seals inside of your
Speaker 1: cheek are epiphilial cells, which I always equate with cells
Speaker 1: that come from your skin. Well, they come from they
Speaker 1: come from the outside of the new organ. Okay, I'm
Speaker 1: learning a lot, you know, Karen, start joining me in
Speaker 1: New York psychologists. Why are so many people afraid to
Speaker 1: get a DNA test? I think they were prey nancy
Speaker 1: to find out things that they don't know, and the
Speaker 1: unknown can often be scary, and especially if you get
Speaker 1: health information and they wonder, well, what do I do
Speaker 1: about its information once they get it? Okay, Karen, you're
Speaker 1: so smart. You know what? You just hit the nail
Speaker 1: on the head. Because, um, when we decided to do
Speaker 1: twenty three and me, I was reading about it my daughter,
Speaker 1: this is why we did it. My daughter wants to
Speaker 1: know her ancestry. And I said, you're Irish, and I
Speaker 1: go to bed just you know, I didn't know what
Speaker 1: else to say. That's all I knew. Um, but I
Speaker 1: knew that there was more in the mix because my
Speaker 1: mother is deeply all of skinned, with black hair and
Speaker 1: amazing blue eyes, and I come out with, you know,
Speaker 1: really really white and and hazel eyes and blonde hair,
Speaker 1: and my dad was ready complexed. And I'm wondering how
Speaker 1: does all this mix together when we're basically mutts. But
Speaker 1: that aside, Karen, start what you said. When I started
Speaker 1: thinking about taking doing twenty three and me and the
Speaker 1: spit party, I think either Stacy or Elsa said spit party.
Speaker 1: I said, sure, I want to know all my health information.
Speaker 1: I wan't to know everything, but when I got the report,
Speaker 1: I had to tell you I did have a tiny
Speaker 1: hesitation when I clicked on UM, I clicked on health.
Speaker 1: It's really easy to read. Everybody, you get it in
Speaker 1: your email or wherever you want it sent, and don't
Speaker 1: ruin it you for or you Jackie, because guys, Jackie
Speaker 1: is our executive producer on Crime Stories. So Lucy has
Speaker 1: always wanted her ancestry. And I'm going to print it
Speaker 1: all out and make it like a college diploma looking
Speaker 1: thing and wrap it in a ribbon. And that's going
Speaker 1: to be one of her Christmas gifts. Okay, not from Santa,
Speaker 1: but from me and so don't tell or anything we're
Speaker 1: talking about, especially you care and start. So I was
Speaker 1: a little bit afraid when I just a tiny bit,
Speaker 1: I had a pause. So let me go back to you,
Speaker 1: Stacy Debt. While are joining US Medical Affairs Manager, what
Speaker 1: type of health information can I learn from twenty three
Speaker 1: and me? Yeah, so the Helpless Ancestry Service. There's a
Speaker 1: lot of different health replaces in there, and the big
Speaker 1: ones that we think about are the ones that why
Speaker 1: you information about your own likelihood or chances for developments
Speaker 1: like type two diabetes UM. So this is using your
Speaker 1: own genetic information. There's also the more general wellness one,
Speaker 1: so big one that I think about is likelihoods of
Speaker 1: being lack of all learning um. But there's also reports
Speaker 1: that can provide information about there. Do you have a theory,
Speaker 1: a genetic theory that you might pass on your future
Speaker 1: children that could impact them? It helps too, So being
Speaker 1: a genetic health I always think about the family aspect.
Speaker 1: There's a little bit for you, there's a little bit
Speaker 1: potentially for family members as well. There's a lot of
Speaker 1: different information that you can get miss um. There's even
Speaker 1: the twenty plus membership that even opens that up more
Speaker 1: already the additional UM insights. So there's a lot of
Speaker 1: different health information that you've learned about. It's not diagnostics,
Speaker 1: but it can ultimately lead you into the passes talking
Speaker 1: to your healthcare providers. I mean a potential life change, diagnosis,
Speaker 1: UM or a lot of these healthy lifestyle is the
Speaker 1: prevention as that can really promote these actions that you
Speaker 1: can take every day to help you live a longer, happier,
Speaker 1: healthy life. Well, I gotta tell you I learned a lot.
Speaker 1: I learned that I have a higher risk of getting
Speaker 1: cilliac disease. Now, can somebody tell me what that is exact? Actually?
Speaker 1: What is that? Dr dupree Ciliac disease. That's physically a
Speaker 1: sensitivity to gluten which is found in flour and wheats
Speaker 1: and things like that. Right, you're not telling me to
Speaker 1: cut out carbs, are you? Because I don't want to
Speaker 1: hear that. I'm not telling you. Well, I'm saying it
Speaker 1: might be a good ideas slightly higher risk. It is
Speaker 1: not high risk, slightly higher exactly. And they also propensity,
Speaker 1: It doesn't mean that it's going to happen. You had
Speaker 1: a propensity for that also increased likelihood of type two diabetes. UM.
Speaker 1: Explain what that means, Dr Dupree. But type two diabetes
Speaker 1: UM means that you usually acquire diabetes later in life. UM.
Speaker 1: It is UM. It can be controlled by medication. It
Speaker 1: can also be controlled by nothing more than diet and exercise. UM.
Speaker 1: If it hasn't progressed too far, it may require medicines
Speaker 1: such as pills, and it may actually try into insul independence.
Speaker 1: It's usually found in older adults. UM. But again you're
Speaker 1: saying it can be prevented. It can be with diet
Speaker 1: and exercise. It can be you can actually change your
Speaker 1: your diagnosis basically of diabetes sometimes if it hasn't progressed
Speaker 1: your part and if you're on a very healthy diet
Speaker 1: and UM exercise. You know what else is interesting? Elisa
Speaker 1: Lehman joining me senior manager product Science at twenty three.
Speaker 1: In me, everything was dead on it's My results were
Speaker 1: higher odds of hazel eyes, which I have afraid likely
Speaker 1: to be afraid of heights. I am not afraid of heights.
Speaker 1: My father, however, hated heights, hated hyson. I will tell
Speaker 1: you after hiking a lot Alisa all Over that when
Speaker 1: I get to the top of a let's say, mountain,
Speaker 1: finally get to the top of it. I'm not afraid
Speaker 1: from the waist up, but from the waist down, my
Speaker 1: legs seem to tremble. I can always feel it, Like
Speaker 1: when we went to the top of a summit Grand
Speaker 1: Can and I look down. I was talking about how
Speaker 1: beautiful it was and trying to take pictures, but my
Speaker 1: legs were shaking. What does that mean? I guess that
Speaker 1: would be the fear of het Maybe a little part
Speaker 1: of you still still care, is that? I think? What's
Speaker 1: you know really interesting about you know, all the information
Speaker 1: that you can get with twenty three and me, is
Speaker 1: you see, like how many things in your life. Jenetics
Speaker 1: may have a little roll in, right, it may nudge
Speaker 1: you towards one thing or another. But as you said,
Speaker 1: it's not destiny, right, it's a it's a propensity maybe,
Speaker 1: but you may not be afraid of heights. Maybe you
Speaker 1: know that beautiful view overcomes that fear for you, and
Speaker 1: you know, like you said, legs up, you are just
Speaker 1: enjoying that beautiful view, and a propensity for fear of
Speaker 1: pipe doesn't matter at that point. How in the world, though,
Speaker 1: do your chromosomes. Um, Jackie's holding a basson. Not afraid
Speaker 1: of hies, but am afraid of falling. Okay, thank you, Jackie.
Speaker 1: How do janette markers determine if you're afraid of heights?
Speaker 1: Because my father was definitely afraid of heights. I've never
Speaker 1: heard that before. Anybody jump in that knows the answer
Speaker 1: to that one, Well, I can tell you at twenty
Speaker 1: three and me. What we do is we look at
Speaker 1: people who tell us they're afraid of heights and compare
Speaker 1: their DNA to people who say they're not afraid of heights.
Speaker 1: And what we're looking for is differences, like different places
Speaker 1: in their d n A that's different between those two groups.
Speaker 1: And so we can say that people who have who
Speaker 1: are afraid of heights tend to have this certain genetic
Speaker 1: marker that people who aren't afraid of heights who don't have.
Speaker 1: And then we can tell you that that you may
Speaker 1: have this marker that seems to be associated with being
Speaker 1: afraid of heights. You know, really interesting thing I found
Speaker 1: out my mom has natural degeneration and and my mother
Speaker 1: in law, who believe it or not, Jackie, ever since
Speaker 1: the David and I met back in college over all
Speaker 1: those years, I never had a single cross word with
Speaker 1: his mother or father. Yeah, I'm really really blessed, just
Speaker 1: just so blessed to had them in my life. His
Speaker 1: mother had macular degeneration really badly. Now here's what's interesting.
Speaker 1: I don't show a higher likelihood of getting macular degeneration,
Speaker 1: but my husband does. I haven't told him yet. He's
Speaker 1: kind of like shut down after he found out he
Speaker 1: wasn't Scottish. Okay, so that's a whole another thing. He
Speaker 1: is so convinced he's Scottish. We even bought him a
Speaker 1: kilt and made him wear at one time. Um, he's not.
Speaker 1: He's not Scottish. I think that he's questioning the whole
Speaker 1: oh process because he wants to be Scottish so badly.
Speaker 1: He loves bagpipes, he loves everything about it. But he
Speaker 1: found out that he's a mutt like me and um,
Speaker 1: and he's got a little bit of French in German
Speaker 1: and him, and he was just he was upset when
Speaker 1: he found out our so called thoroughbred dockson was part poodle. Okay.
Speaker 1: He was very disturbed about that. So I haven't been
Speaker 1: able to talk to him about being part French and
Speaker 1: part German. Yet I'm going to save it for just
Speaker 1: the right moment. But you know, another thing I found
Speaker 1: out is that, Um, I knew that I was part Jewish,
Speaker 1: but I didn't know it was Ashkenazi. Now that is
Speaker 1: very significant because there are certain health risks associated with
Speaker 1: being Ashkenazi. Does anybody know the answer to that? What
Speaker 1: are those health risks? Yeah? I can jump in here. Um,
Speaker 1: there's certain populations, whether genetic variants that occur more common,
Speaker 1: as Nazi Jewish is one of those that we see
Speaker 1: certain genetic condition much more common in that population. And
Speaker 1: so one of the ones that we think about is
Speaker 1: the r are um inheriting breast cancer, had a hereditary
Speaker 1: breast cancer and or variating cancer. This frest and hold
Speaker 1: on running that down. Hereditary breast cancer, hereditary a varying cancer. Yes,
Speaker 1: the rday line and r C too, and so individuals
Speaker 1: of oh yeah, just so you know, ladies, Karen Stark's
Speaker 1: breast cancer survivor, go ahead and georr you Oscanazi Karen?
Speaker 1: So you know we're related. Not only did we live
Speaker 1: down the street from each other in New York, now
Speaker 1: we find out we're related. Okay, breast cancer, hereditary breast
Speaker 1: cancretary of varying cancer, the brocka Chaine, and I believe
Speaker 1: tastes lock syndrome, isn't that. Yeah, there's a lot of
Speaker 1: conditions that are autosomal respessive, which is a fancy way
Speaker 1: of saying that kind of you inherited that experience from
Speaker 1: your both room parents, and that can result from the condition.
Speaker 1: And we see more of the like thing in certain populations.
Speaker 1: And so for the r A you're talking about, that
Speaker 1: about one in forty individuals of the Jewish ancestry are
Speaker 1: barriers or habits a variance that greatly increases the risk
Speaker 1: for these certain cancers like breasco various or costee anatic.
Speaker 1: You know, I found out so much about my mom too, guys.
Speaker 1: I found out that she is partially Nigerian. I found
Speaker 1: out so much about mom. What what is that you
Speaker 1: care and start jeffing and go ahead. Yeah. I wanted
Speaker 1: to say, like, if if you get those kind of
Speaker 1: results and they say a potensity to a dist or
Speaker 1: something about the brothogene, it's really important not to be afraid,
Speaker 1: but to go and talk to somebody and go over
Speaker 1: it with your doctor or a genetic counsels like you
Speaker 1: have on the show. Hey, you know what it did
Speaker 1: to me when I found out, um, about the higher
Speaker 1: likelihood of getting type two diabetes. Well, first immediately ordered
Speaker 1: Crispy Kream's and I ate my way through them. Then
Speaker 1: I swore them off. I'm trying. I have one last
Speaker 1: beender before I went on Straight and Narrow. But anyway
Speaker 1: back to twenty three and me, and can we talk
Speaker 1: about security, because um, I found out all sorts of
Speaker 1: things in my line of work. When you talk about
Speaker 1: d n A tists, it's never a good thing. Okay,
Speaker 1: you know it's as related as I'm crying. But with
Speaker 1: twenty three and me, Um, you can now explain this correctly.
Speaker 1: Stacy dett Wilder and Alisa Lehman. You can actually have
Speaker 1: all of your your results destroyed after you get them.
Speaker 1: If you don't want them kept on file, They're destroyed.
Speaker 1: They're gone, like turning off the TV. It's over. It's gone. Um.
Speaker 1: You can have it not shared with the public or
Speaker 1: shared with the public if you want. You can have
Speaker 1: limited parts of it shared with the public or none
Speaker 1: of it shared with the public. Is it is all
Speaker 1: of that right? Alisa and or Stacey. Yeah, that's right,
Speaker 1: and I encourage everyone to check out twenty three and
Speaker 1: me dot com slash privacy because I think you're right
Speaker 1: that a lot of people think about the privacy and
Speaker 1: the security concerns about getting this information. And we want
Speaker 1: people to make an informed choice before they decide to
Speaker 1: do test or not. And so we have a lot
Speaker 1: of information about what is what we do to protect
Speaker 1: your information. So, yes, you can have your sample destroyed,
Speaker 1: your DNA sample that you provide. You can completely delete
Speaker 1: all your information after you after you get it. You
Speaker 1: can download all your information. You can choose UM which
Speaker 1: reports that you want to view or not view, and
Speaker 1: UM within the health reports, you can choose if you
Speaker 1: want to share information with other people on the twenty
Speaker 1: three and me site or with research or not UM,
Speaker 1: and you can use what information is shared. So you
Speaker 1: have a lot of control over who sees your information.
Speaker 1: And we want to make sure that people are you know,
Speaker 1: informed of those choices ahead of time. And our general
Speaker 1: policy is that all of these things are opting into sharing.
Speaker 1: So if you don't do anything, we assume you do
Speaker 1: not want to have your information and shared. Oh that's
Speaker 1: so smart. Guys, what she just said. I just immediately
Speaker 1: compared it to if you're in court and you don't
Speaker 1: interimpl the judges automatically and there's not guilty for you.
Speaker 1: If you don't check any of these boxes, then they
Speaker 1: automatically put it on privacy where you don't share it
Speaker 1: with anyone in any degree. And again you can have
Speaker 1: the whole thing deleted and your tests destroyed if that's
Speaker 1: what you want. Hey, you know what another thing I
Speaker 1: found out? This is so crazy, then I am wait
Speaker 1: for it, Jackie, wait for it. More likely to experience
Speaker 1: here photo bleaching, which means that when you out in
Speaker 1: the sun, your hair turns blonder. See. I told you
Speaker 1: this was natural, and you didn't believe me. You kept saying,
Speaker 1: who did your hair? Or who did not do your hair?
Speaker 1: Can't han't, can't go do your hair. See it's all
Speaker 1: because of the sun. This is natural, right? How do
Speaker 1: they know that? Can Alice or Stacy tell me that
Speaker 1: that is? That is very similar to you know, the
Speaker 1: fear of heights, um, you know, fear of public speaking,
Speaker 1: like preferences like you know, whether you prefer chocolate or
Speaker 1: vanilla ice cream? All of that is you know, comparing
Speaker 1: the DNA as people who who say their hair gets
Speaker 1: lighter in the sun to people whose hair doesn't get
Speaker 1: lighter in the sun, and finding these little places that
Speaker 1: are are different between people who have those different experiences,
Speaker 1: and then again being able to report back to you
Speaker 1: based on your DNA you might be more likely to
Speaker 1: have that hair photo bliefing happen. Listen to this, guys.
Speaker 1: This is what you can learn. Are you prone to
Speaker 1: type two diabetes? If so, what can you do about it?
Speaker 1: Im macular degeneration? What can David and Lucy do about it?
Speaker 1: I found out that I was more acutely, I have
Speaker 1: a more acute odor detection, which is really interesting. Jackie
Speaker 1: Karen start. Remember after COVID, both John, David and I
Speaker 1: lost a sense of smell, and um I first tested
Speaker 1: about midnight. We were up watching Elf, the Christmas movie,
Speaker 1: and um I realized I couldn't smell Lucy's cookie shoes making,
Speaker 1: and we went and stuck our noses in the coffee.
Speaker 1: Couldn't smell it. We finally the Ultimate Desk got two
Speaker 1: sharpies and stuck them up our nostrils. Couldn't smell a thing,
Speaker 1: And I'm like, okay, we've lost our sense of smell.
Speaker 1: Now listen to this Karen start over. A year later,
Speaker 1: I think my mother smells funny. Then I thought my
Speaker 1: friend who often comes on our program when a rockwell
Speaker 1: smelled funny, same smell, Jackie. Sadly, I also thought you
Speaker 1: smelled funny. Finally, finally I thought, how can all these
Speaker 1: three people smell like blee? It's me. I went to
Speaker 1: the doctor and it was a result, weird result of
Speaker 1: COVID having lost my smell. And now I find out
Speaker 1: through twenty three and me I have increased odor detection,
Speaker 1: more likely to match a musical pitch boy. I wish
Speaker 1: David had gotten that one. UM fear of high fear
Speaker 1: of public speaking. And you learn about these things in
Speaker 1: order to work on them and maybe even correct them. Um.
Speaker 1: It talks about possibility of chronic kidney disease, the possibility
Speaker 1: of hyper cholesterol, and me cholesterol, Ama, what is that?
Speaker 1: Is that? Bad cholesterol? What is that? Dr Dupree? Basically
Speaker 1: hyper cholesterol a media hyper cholesterol limia. It is actually
Speaker 1: you have more what they call bad cholesterol or l
Speaker 1: D all the low density, then you do the high density,
Speaker 1: and therefore you are more susceptible to things like stroke,
Speaker 1: hardening of the arteries, um, even heart attack. Well I
Speaker 1: dodged that one, so I guess it's okay to order
Speaker 1: another round of Crispy krans Um. Let's see. Well, I'll
Speaker 1: jump in here shop the end our reports. Yeah, I
Speaker 1: reports specifically on familial hope for cholesteroling you, which is
Speaker 1: an inherited So why did about people have this? And
Speaker 1: so you're typically very early on you have very high cholesterol.
Speaker 1: So unfortunately, most pieces of having a high cholesterol are
Speaker 1: due to and lifestyle. Um. So you know you can't
Speaker 1: go take a while there. Well, so that's an X
Speaker 1: on the own at days. That's a note to the
Speaker 1: doughnuts legal legally as I'm throwing you. I'm not gonna
Speaker 1: say completely not, it's not a total note. Why did okay,
Speaker 1: why does John David have to take his test again?
Speaker 1: I think did? Did? Did he screw it up somehow? Does?
Speaker 1: Why would he have to take his test again? Did
Speaker 1: he not spit enough? This can happen um so often
Speaker 1: it's because you know, like I said, these cells in
Speaker 1: your cheeks, that's what we're looking for, um in your spit.
Speaker 1: So it could be that either there weren't enough cells
Speaker 1: for whatever reason, um that that made it into his
Speaker 1: first fit sample. It could be that, you know, when
Speaker 1: we when we extract the DNA out of those cells,
Speaker 1: that we didn't get enough, or could be that you
Speaker 1: know when we are trying to analyze your DNA, that
Speaker 1: there was there was an error or problem with that analysis.
Speaker 1: But hopefully you know, his experience was that you got
Speaker 1: a second kid was able to give it a second try,
Speaker 1: and we were successful that on that second on the
Speaker 1: second try. I'm trying, but you can't eat or drink
Speaker 1: thirty minutes before, and it's really hard to catch John
Speaker 1: David having not just eating something. So I'm trying to
Speaker 1: pin him down before he can eat or drink in
Speaker 1: the morning to do spent Yes, Karen Stark, Uh, he's
Speaker 1: six five and a half and he just turned fifteen.
Speaker 1: You know, a feeding full of vegetables every night. Last
Speaker 1: night he bought at Raw Carrot's. I don't know why,
Speaker 1: but he did. But I'm working on it. I'm working
Speaker 1: on it. Yes, maybe guys. It's also very easy to
Speaker 1: view online. I don't know how it's gonna be to
Speaker 1: print it off and I make Lucy's um Christmas scroll.
Speaker 1: But and that's not all I'm giving her. I'm giving
Speaker 1: her some other things too, And of course Santa's coming.
Speaker 1: You can delete your account, discard your sample, no one
Speaker 1: can access your information if that's the way you want it.
Speaker 1: I'm really happy that I took the test. I'm really
Speaker 1: happy that I will be able to answer some of
Speaker 1: Lucy's questions. She's Brettish, she gets some Scandinavian from her father.
Speaker 1: She gets a lot of Irish from me. She and
Speaker 1: I'm assuming since they're twins, John Davis, they're both going
Speaker 1: to have osh Can Nazi jeans within them. Of course
Speaker 1: that opens up to a lot of health issues we're
Speaker 1: going to look into. But now I know, and now
Speaker 1: I can do something about it for them. Um, I'm
Speaker 1: just really glad it came in into my wife. Hey,
Speaker 1: let's let's do round robin. Final thoughts. Dr Michelle Duffrey.
Speaker 1: I think this is a wonderful You can actually change
Speaker 1: your lifestyle based on the information that you know and
Speaker 1: have a better life. I help their life. This is great,
Speaker 1: you know, it really is. Isn't it great to be
Speaker 1: talking about genetic markers when it's not connected to a crime. Okay, Karen,
Speaker 1: start and jump in. I just think that. I mean,
Speaker 1: I did it, and there was nothing that was frightening.
Speaker 1: I felt like if I needed to, I would certainly
Speaker 1: consult you're the doctor or a genetic council. But there
Speaker 1: was a lot of things. There were things I said
Speaker 1: that that we're fun, like the chocolate or the vanilla,
Speaker 1: because my whole family likes vanilla and people are like, what,
Speaker 1: no chocolate? It was really a lot of fun to
Speaker 1: get that information. What about it? Alisa Lehman joining me
Speaker 1: PhD seeing you manage your products science at twenty three
Speaker 1: and me, I mean, I think it's great to hear
Speaker 1: the good experiences that people are having, and it's exactly
Speaker 1: what we want, as you know, a starting point stirt
Speaker 1: your journey, either with your ancestry or with your health.
Speaker 1: You know, take this and and make good choices going
Speaker 1: forward and to Stacy while or maybe this is to
Speaker 1: at least I'm not sure who would feel this. But
Speaker 1: we almost didn't do it, And I'll tell you why.
Speaker 1: When I said, hey, Twins, you want to do twenty
Speaker 1: three and me after I told him what it was,
Speaker 1: John Davis said no, Mom, because I don't want my
Speaker 1: great great grandson to be busted on a felony because
Speaker 1: I gave a DNA sample And I almost said, where
Speaker 1: did you hear that? And then of course I need
Speaker 1: where he heard it from me? Okay talking about it
Speaker 1: ancestral family trees, and I just want to point out
Speaker 1: to Allay my son John David's fears. Twenty three and
Speaker 1: me has never once handed out information to law enforcement.
Speaker 1: And again they give you the option if you want
Speaker 1: your test destroyed, It's destroyed when you say do it.
Speaker 1: Stacy Detwiler final thoughts. You know, I think our mission
Speaker 1: this was people to access, understand and benefit from this information.
Speaker 1: And it's so great to hear UM that it seems
Speaker 1: like we've done that. We are all about the heart right.
Speaker 1: This is your information. You have access to learn so
Speaker 1: much from it, Um and inspire you to make the
Speaker 1: positions that are going to lead to that longer have
Speaker 1: to healthier life what we want. I just want to
Speaker 1: say thank you to twenty three and me UM for
Speaker 1: all the questions you've answered, and I will let you
Speaker 1: know how Lucy response on Christmas morning. Thanks guys, goodbye friends,
Speaker 1: and that's it. On another dope show. Did this episode
Speaker 1: inspire you to take a closer look at your health history,
Speaker 1: your genetic makeup. Who new DNA could reveal so much
Speaker 1: about our past while also holding the keys to certain
Speaker 1: health insights that may impact our future. I continue to
Speaker 1: be inspired by these stories, and I hope you do
Speaker 1: as well. Catch you next time. Listen to Spit, an
Speaker 1: original podcast from I Heart Radio and twenty three in
Speaker 1: the on the I Heart Radio app, Apple podcast, or
Speaker 1: wherever you get your podcast.