WEBVTT - Crime Stories with Nancy Grace: Unlock Your Own DNA Mystery! 0:00:03.279 --> 0:00:06.560 Have you ever thought about how incredibly complex I spit is. 0:00:07.240 --> 0:00:11.280 It may only be water, but just aliva isn't simple. 0:00:11.800 --> 0:00:16.320 That remaining one percent holds incredibly meaningful information that could 0:00:16.480 --> 0:00:19.360 change everything. And I'm not just talking about your family 0:00:19.440 --> 0:00:23.640 treat Hi. I'm Barret to day Thurston. And on this 0:00:23.680 --> 0:00:26.320 season of Spit and I Heart Radio podcast with twenty 0:00:26.320 --> 0:00:30.440 three and Me, we explore how DNA isn't just about ancestry, 0:00:30.800 --> 0:00:37.360 it can also be key to understanding your health. Hello, Hello, 0:00:37.440 --> 0:00:42.400 and welcome back to another episode of Spit. Today we've 0:00:42.400 --> 0:00:45.880 got the one and only host of crime Stories, Nancy Grace. 0:00:46.600 --> 0:00:49.040 Nancy's taking a break from true crime to get to 0:00:49.080 --> 0:00:52.880 the bottom of an entirely different investigation her twenty three 0:00:52.880 --> 0:00:55.680 and Me Test reports. You might know Nancy as one 0:00:55.720 --> 0:00:58.640 of the fiercest legal analysts around, but she's also a 0:00:58.640 --> 0:01:01.360 proud mother of twins. Well, Nancy has covered some of 0:01:01.360 --> 0:01:04.240 the most famous and infamous cases in American true crime. 0:01:04.680 --> 0:01:06.920 She's also been known to share the fears and triumphs 0:01:06.920 --> 0:01:09.800 of motherhood with her listeners. So when Nancy and her 0:01:09.840 --> 0:01:12.800 family recently took a twenty three me test, she just 0:01:12.880 --> 0:01:15.759 had to let her listeners in on the journey, Nancy 0:01:15.800 --> 0:01:17.600 sits down with a panel of experts to get a 0:01:17.640 --> 0:01:21.000 better understanding of her family's reports and the role genetics 0:01:21.000 --> 0:01:23.920 play in their health. And connecting all the dots, she 0:01:24.040 --> 0:01:27.119 explores the science behind the test and looks to show 0:01:27.160 --> 0:01:30.240 listeners how the information contained in twenty three and me 0:01:30.360 --> 0:01:33.600 reports can empower you on the journey to a healthier life. 0:01:34.200 --> 0:01:49.720 Let's listen. In twenty three and me, you'd have to 0:01:49.760 --> 0:01:53.960 be living under a rock in a cave in a 0:01:54.080 --> 0:01:57.720 far away distantly and not to know what three and 0:01:57.920 --> 0:02:05.360 me is. It's ancestry testing. You find out where you're from, 0:02:05.480 --> 0:02:12.280 who you are so to speak, uh, chromosomely genetically that is, 0:02:13.800 --> 0:02:19.880 can that discovery unlock secrets the secrets of your genetic 0:02:19.960 --> 0:02:25.400 makeup that can help you lead healthier and I believe 0:02:25.600 --> 0:02:33.120 happier life. We hear stories about genetic tracing that you 0:02:33.120 --> 0:02:37.480 you find distant relatives, You find out your family tree 0:02:37.600 --> 0:02:40.800 goes all the way back to Anglo Saxon times. But 0:02:40.960 --> 0:02:43.160 how can it help me into here? And now I'm 0:02:43.240 --> 0:02:47.200 raising two twins they just turn fifteen. Let me wash 0:02:47.280 --> 0:02:50.440 my mouth out with soap. I can't believe they're fifteen. 0:02:51.480 --> 0:02:57.400 Can I learn anything from this genetic Uh? Let me 0:02:57.480 --> 0:03:04.720 say genetic makeup, genetic identity, genetic composite that will help 0:03:04.919 --> 0:03:07.480 my twins and me and my husband David and my 0:03:07.560 --> 0:03:14.359 mother Elizabeth live a longer, healthier life. I'mancy Grace and 0:03:14.480 --> 0:03:17.600 we are talking about twenty three and me with me 0:03:17.680 --> 0:03:20.720 an all star panel to make sense of all of this. 0:03:20.800 --> 0:03:22.440 If you're a LA person like me, I I'm just 0:03:22.480 --> 0:03:27.440 a j D. But I know nothing about genetic counseling. 0:03:27.600 --> 0:03:31.680 What does it mean? Joining me up an incredible host 0:03:31.720 --> 0:03:34.079 of yes, But I want to go first to Stacy 0:03:34.320 --> 0:03:40.320 debt Wiler. She is a license certified genetic counselor with 0:03:40.480 --> 0:03:43.800 twenty three and me, Stacy, thank you so much for 0:03:43.920 --> 0:03:47.120 being with us. Thank you here? What is in a 0:03:47.240 --> 0:03:50.280 nutshall remember? This is twenty three? And me for dummy's 0:03:50.480 --> 0:03:53.720 what is twenty three? And me? Hey, guys, by the way, 0:03:53.920 --> 0:03:57.840 I took the test, Go ahead tell me Stacy. It's 0:03:57.840 --> 0:04:00.360 a lot right. Um. So I think you you kind 0:04:00.360 --> 0:04:03.560 of mentioned what people first thing about is ancestry. But 0:04:03.720 --> 0:04:06.600 what I really get excited about it the hall. And 0:04:06.640 --> 0:04:08.960 there is a lot of information that you can find 0:04:08.960 --> 0:04:11.400 out from a little bit of spit which we're able 0:04:11.440 --> 0:04:14.960 to get DNA from, so there's information about your own Wait, 0:04:15.000 --> 0:04:17.640 did you say a little bit of spit? Because we 0:04:17.720 --> 0:04:21.800 have to spit and spit and spit. I mean I'm 0:04:21.839 --> 0:04:25.680 used to quiminal cases, Stacy, where you get a genetic 0:04:26.040 --> 0:04:30.120 marker and identity, and like this is mina skill amount 0:04:30.440 --> 0:04:35.240 of I don't blood saliva. Why did we have to 0:04:35.279 --> 0:04:38.560 spit so much? Yeah, that's why we fall the spit party. Um, 0:04:38.760 --> 0:04:41.480 I didn't think about it like that. I don't let 0:04:41.480 --> 0:04:44.560 to Alisa take this one a little bit, um, just 0:04:44.640 --> 0:04:47.120 because there's you know, you need to get enough DNA 0:04:47.680 --> 0:04:50.120 from that spit in order to be able to give 0:04:50.160 --> 0:04:54.360 you all these insights. Um, who's over six five? Okay, 0:04:54.360 --> 0:04:57.200 I'll go to Alisa with me is a Lisa Lehman, 0:04:57.320 --> 0:04:59.640 Senior manager and product science at twenty three and me 0:05:00.279 --> 0:05:03.840 and you can find everybody at medical dot twenty three 0:05:03.880 --> 0:05:07.800 and me dot com and it's and spelled out twenty 0:05:07.800 --> 0:05:10.680 three and me dot com atly soa welcome to you 0:05:10.720 --> 0:05:13.839 and Stacy. Why so much spit? You know you're a 0:05:13.839 --> 0:05:16.680 pH d and a senior manager. I feel kind of 0:05:16.920 --> 0:05:19.559 wrong asking you why did I have to spit so much? 0:05:19.680 --> 0:05:21.480 But why did I have to spit so much? Oh? 0:05:21.560 --> 0:05:23.599 Thank you for having me? And why do you have 0:05:23.640 --> 0:05:25.960 to sit so much? As the best question I think 0:05:26.279 --> 0:05:29.360 to ask, I'd love I'd love answering questions like this. Um. 0:05:29.360 --> 0:05:31.719 Like Stacy said, right, what we're trying to do is 0:05:31.839 --> 0:05:34.839 get your d NA um the easiest way possible. Right. 0:05:34.839 --> 0:05:36.520 We don't want people to have to go give us 0:05:36.520 --> 0:05:40.000 a blood sample, so spit very easy to get. But 0:05:40.440 --> 0:05:42.839 what we're doing is we're trying to get the d 0:05:42.960 --> 0:05:45.320 N A that's in almost every cell in your body, 0:05:45.400 --> 0:05:48.320 including the cells inside your cheeks. So when you spit 0:05:48.400 --> 0:05:51.200 and spit and spit, what's coming along for the ride 0:05:51.279 --> 0:05:54.240 is some of those cheek cells um from from your mouth. 0:05:54.560 --> 0:05:56.400 And what we're trying to do is make sure that 0:05:56.440 --> 0:05:58.560 we're going to get enough of those cells so we 0:05:58.600 --> 0:06:01.440 get enough DNA to make sure that when we run 0:06:01.480 --> 0:06:04.520 and analyze that DNA extracted from the cells, when we 0:06:04.600 --> 0:06:07.640 try and figure out your a's and seas and teas 0:06:07.680 --> 0:06:10.080 and gees from your DNA, that we have enough so 0:06:10.160 --> 0:06:11.919 you don't have to do it again. What are a's 0:06:12.000 --> 0:06:15.280 and seas and Jason T So your DNA you can 0:06:15.279 --> 0:06:20.360 think of as a code that is there to um 0:06:21.560 --> 0:06:24.400 explain how to you know what? Alsa lame and just 0:06:24.440 --> 0:06:29.320 stop right there. My son who is a star in 0:06:29.680 --> 0:06:34.120 robotics and science, and he keeps talking about coding, and 0:06:34.160 --> 0:06:36.159 I keep acting like I know what he's talking about. 0:06:36.400 --> 0:06:39.919 What are you talking about? So when I'm talking about 0:06:39.920 --> 0:06:43.159 the genetic code, it is more like you know codes 0:06:43.240 --> 0:06:46.840 during World War Two where you are trying there's information, 0:06:47.320 --> 0:06:50.200 but it is written in a way that you know 0:06:50.279 --> 0:06:52.839 you need to be able to decode it to understand it. 0:06:53.760 --> 0:06:57.720 So your DNA is like that. Okay, now I understand. 0:06:57.960 --> 0:07:01.760 Now I understand with me to new friends Stacy Entwiler 0:07:02.040 --> 0:07:05.120 and Alsa Lehman from twenty three and me and who 0:07:05.480 --> 0:07:09.520 longtime friends Karen Start joining us were now psychologists joining 0:07:09.600 --> 0:07:11.280 us out of Manhattan. You can find her at karen 0:07:11.320 --> 0:07:14.200 Start dot com. That's Karen with a C. And Dr 0:07:14.240 --> 0:07:19.280 Michelle dupre, my longtime colleague joining us out of South Carolina, 0:07:19.960 --> 0:07:26.400 forensic pathologist, medical examiner, author of multiple books. Dr Dupree, now, 0:07:26.560 --> 0:07:32.200 what about this a regular role? PhD just told me 0:07:32.320 --> 0:07:34.800 something you've never told me. I've never heard the phrase 0:07:34.880 --> 0:07:37.920 cheek seals have you heard the phrase cheek sales, Jackie. Yeah, 0:07:38.080 --> 0:07:42.360 you've never mentioned that. Dupre no. I always say epithelial sales, 0:07:42.640 --> 0:07:45.680 and you crashed down on me for using such a 0:07:45.720 --> 0:07:50.160 technical term. Yeah, do so. The seals inside of your 0:07:50.240 --> 0:07:54.600 cheek are epiphilial cells, which I always equate with cells 0:07:54.720 --> 0:07:56.960 that come from your skin. Well, they come from they 0:07:57.000 --> 0:07:59.120 come from the outside of the new organ. Okay, I'm 0:07:59.200 --> 0:08:01.760 learning a lot, you know, Karen, start joining me in 0:08:01.760 --> 0:08:04.320 New York psychologists. Why are so many people afraid to 0:08:04.360 --> 0:08:07.720 get a DNA test? I think they were prey nancy 0:08:07.800 --> 0:08:11.200 to find out things that they don't know, and the 0:08:11.320 --> 0:08:15.320 unknown can often be scary, and especially if you get 0:08:15.360 --> 0:08:18.920 health information and they wonder, well, what do I do 0:08:18.960 --> 0:08:22.800 about its information once they get it? Okay, Karen, you're 0:08:22.840 --> 0:08:24.760 so smart. You know what? You just hit the nail 0:08:24.800 --> 0:08:29.080 on the head. Because, um, when we decided to do 0:08:29.160 --> 0:08:32.160 twenty three and me, I was reading about it my daughter, 0:08:32.240 --> 0:08:34.040 this is why we did it. My daughter wants to 0:08:34.080 --> 0:08:36.280 know her ancestry. And I said, you're Irish, and I 0:08:36.320 --> 0:08:39.440 go to bed just you know, I didn't know what 0:08:39.559 --> 0:08:43.400 else to say. That's all I knew. Um, but I 0:08:43.480 --> 0:08:46.480 knew that there was more in the mix because my 0:08:46.559 --> 0:08:52.200 mother is deeply all of skinned, with black hair and 0:08:52.360 --> 0:08:56.920 amazing blue eyes, and I come out with, you know, 0:08:57.360 --> 0:09:03.440 really really white and and hazel eyes and blonde hair, 0:09:03.679 --> 0:09:08.080 and my dad was ready complexed. And I'm wondering how 0:09:08.120 --> 0:09:11.640 does all this mix together when we're basically mutts. But 0:09:11.960 --> 0:09:15.920 that aside, Karen, start what you said. When I started 0:09:15.960 --> 0:09:19.040 thinking about taking doing twenty three and me and the 0:09:19.120 --> 0:09:24.239 spit party, I think either Stacy or Elsa said spit party. 0:09:25.480 --> 0:09:28.080 I said, sure, I want to know all my health information. 0:09:28.480 --> 0:09:31.360 I wan't to know everything, but when I got the report, 0:09:31.480 --> 0:09:33.959 I had to tell you I did have a tiny 0:09:34.040 --> 0:09:38.840 hesitation when I clicked on UM, I clicked on health. 0:09:39.320 --> 0:09:42.200 It's really easy to read. Everybody, you get it in 0:09:42.280 --> 0:09:45.800 your email or wherever you want it sent, and don't 0:09:46.840 --> 0:09:52.640 ruin it you for or you Jackie, because guys, Jackie 0:09:52.800 --> 0:09:57.560 is our executive producer on Crime Stories. So Lucy has 0:09:57.640 --> 0:10:02.040 always wanted her ancestry. And I'm going to print it 0:10:02.080 --> 0:10:05.120 all out and make it like a college diploma looking 0:10:05.160 --> 0:10:07.560 thing and wrap it in a ribbon. And that's going 0:10:07.600 --> 0:10:10.880 to be one of her Christmas gifts. Okay, not from Santa, 0:10:11.679 --> 0:10:16.040 but from me and so don't tell or anything we're 0:10:16.040 --> 0:10:20.520 talking about, especially you care and start. So I was 0:10:20.559 --> 0:10:23.680 a little bit afraid when I just a tiny bit, 0:10:23.760 --> 0:10:26.280 I had a pause. So let me go back to you, 0:10:26.360 --> 0:10:30.680 Stacy Debt. While are joining US Medical Affairs Manager, what 0:10:31.000 --> 0:10:35.880 type of health information can I learn from twenty three 0:10:36.120 --> 0:10:39.200 and me? Yeah, so the Helpless Ancestry Service. There's a 0:10:39.200 --> 0:10:42.160 lot of different health replaces in there, and the big 0:10:42.200 --> 0:10:44.440 ones that we think about are the ones that why 0:10:44.720 --> 0:10:48.679 you information about your own likelihood or chances for developments 0:10:49.240 --> 0:10:52.360 like type two diabetes UM. So this is using your 0:10:52.400 --> 0:10:56.880 own genetic information. There's also the more general wellness one, 0:10:57.040 --> 0:10:59.400 so big one that I think about is likelihoods of 0:10:59.440 --> 0:11:03.160 being lack of all learning um. But there's also reports 0:11:03.160 --> 0:11:07.000 that can provide information about there. Do you have a theory, 0:11:07.080 --> 0:11:09.680 a genetic theory that you might pass on your future 0:11:09.800 --> 0:11:13.480 children that could impact them? It helps too, So being 0:11:13.480 --> 0:11:15.840 a genetic health I always think about the family aspect. 0:11:15.840 --> 0:11:18.240 There's a little bit for you, there's a little bit 0:11:18.280 --> 0:11:21.000 potentially for family members as well. There's a lot of 0:11:21.000 --> 0:11:23.839 different information that you can get miss um. There's even 0:11:23.840 --> 0:11:26.320 the twenty plus membership that even opens that up more 0:11:26.320 --> 0:11:30.240 already the additional UM insights. So there's a lot of 0:11:30.280 --> 0:11:33.520 different health information that you've learned about. It's not diagnostics, 0:11:34.040 --> 0:11:37.319 but it can ultimately lead you into the passes talking 0:11:37.320 --> 0:11:40.480 to your healthcare providers. I mean a potential life change, diagnosis, 0:11:41.120 --> 0:11:44.439 UM or a lot of these healthy lifestyle is the 0:11:44.920 --> 0:11:47.960 prevention as that can really promote these actions that you 0:11:48.000 --> 0:11:51.320 can take every day to help you live a longer, happier, 0:11:51.360 --> 0:11:53.720 healthy life. Well, I gotta tell you I learned a lot. 0:11:54.040 --> 0:11:56.480 I learned that I have a higher risk of getting 0:11:56.760 --> 0:12:00.320 cilliac disease. Now, can somebody tell me what that is exact? Actually? 0:12:00.640 --> 0:12:04.520 What is that? Dr dupree Ciliac disease. That's physically a 0:12:04.559 --> 0:12:08.920 sensitivity to gluten which is found in flour and wheats 0:12:08.960 --> 0:12:10.920 and things like that. Right, you're not telling me to 0:12:10.960 --> 0:12:12.760 cut out carbs, are you? Because I don't want to 0:12:12.760 --> 0:12:16.400 hear that. I'm not telling you. Well, I'm saying it 0:12:16.440 --> 0:12:19.240 might be a good ideas slightly higher risk. It is 0:12:19.280 --> 0:12:24.240 not high risk, slightly higher exactly. And they also propensity, 0:12:24.320 --> 0:12:26.000 It doesn't mean that it's going to happen. You had 0:12:26.000 --> 0:12:32.719 a propensity for that also increased likelihood of type two diabetes. UM. 0:12:33.000 --> 0:12:36.920 Explain what that means, Dr Dupree. But type two diabetes 0:12:37.200 --> 0:12:42.440 UM means that you usually acquire diabetes later in life. UM. 0:12:42.520 --> 0:12:45.880 It is UM. It can be controlled by medication. It 0:12:45.880 --> 0:12:49.040 can also be controlled by nothing more than diet and exercise. UM. 0:12:49.200 --> 0:12:52.560 If it hasn't progressed too far, it may require medicines 0:12:52.559 --> 0:12:55.600 such as pills, and it may actually try into insul independence. 0:12:56.000 --> 0:12:59.520 It's usually found in older adults. UM. But again you're 0:12:59.520 --> 0:13:02.720 saying it can be prevented. It can be with diet 0:13:02.760 --> 0:13:06.160 and exercise. It can be you can actually change your 0:13:07.320 --> 0:13:11.720 your diagnosis basically of diabetes sometimes if it hasn't progressed 0:13:11.760 --> 0:13:14.480 your part and if you're on a very healthy diet 0:13:14.920 --> 0:13:18.079 and UM exercise. You know what else is interesting? Elisa 0:13:18.160 --> 0:13:22.000 Lehman joining me senior manager product Science at twenty three. 0:13:22.040 --> 0:13:27.080 In me, everything was dead on it's My results were 0:13:28.120 --> 0:13:32.760 higher odds of hazel eyes, which I have afraid likely 0:13:32.800 --> 0:13:35.520 to be afraid of heights. I am not afraid of heights. 0:13:35.559 --> 0:13:40.760 My father, however, hated heights, hated hyson. I will tell 0:13:40.840 --> 0:13:46.640 you after hiking a lot Alisa all Over that when 0:13:46.720 --> 0:13:50.680 I get to the top of a let's say, mountain, 0:13:51.120 --> 0:13:54.440 finally get to the top of it. I'm not afraid 0:13:54.559 --> 0:13:58.000 from the waist up, but from the waist down, my 0:13:58.120 --> 0:14:02.880 legs seem to tremble. I can always feel it, Like 0:14:02.960 --> 0:14:04.840 when we went to the top of a summit Grand 0:14:04.880 --> 0:14:07.800 Can and I look down. I was talking about how 0:14:07.840 --> 0:14:10.280 beautiful it was and trying to take pictures, but my 0:14:10.360 --> 0:14:13.319 legs were shaking. What does that mean? I guess that 0:14:13.360 --> 0:14:15.240 would be the fear of het Maybe a little part 0:14:15.240 --> 0:14:17.559 of you still still care, is that? I think? What's 0:14:18.040 --> 0:14:21.400 you know really interesting about you know, all the information 0:14:21.520 --> 0:14:22.920 that you can get with twenty three and me, is 0:14:23.320 --> 0:14:26.120 you see, like how many things in your life. Jenetics 0:14:26.160 --> 0:14:28.400 may have a little roll in, right, it may nudge 0:14:28.400 --> 0:14:30.480 you towards one thing or another. But as you said, 0:14:31.080 --> 0:14:33.760 it's not destiny, right, it's a it's a propensity maybe, 0:14:33.760 --> 0:14:36.520 but you may not be afraid of heights. Maybe you 0:14:36.560 --> 0:14:39.400 know that beautiful view overcomes that fear for you, and 0:14:39.840 --> 0:14:42.480 you know, like you said, legs up, you are just 0:14:42.600 --> 0:14:45.360 enjoying that beautiful view, and a propensity for fear of 0:14:45.400 --> 0:14:50.000 pipe doesn't matter at that point. How in the world, though, 0:14:50.120 --> 0:14:54.640 do your chromosomes. Um, Jackie's holding a basson. Not afraid 0:14:54.640 --> 0:14:57.480 of hies, but am afraid of falling. Okay, thank you, Jackie. 0:14:57.960 --> 0:15:02.240 How do janette markers determine if you're afraid of heights? 0:15:02.240 --> 0:15:05.840 Because my father was definitely afraid of heights. I've never 0:15:05.880 --> 0:15:08.560 heard that before. Anybody jump in that knows the answer 0:15:08.600 --> 0:15:10.640 to that one, Well, I can tell you at twenty 0:15:10.680 --> 0:15:13.000 three and me. What we do is we look at 0:15:13.080 --> 0:15:15.920 people who tell us they're afraid of heights and compare 0:15:16.320 --> 0:15:19.680 their DNA to people who say they're not afraid of heights. 0:15:20.000 --> 0:15:23.400 And what we're looking for is differences, like different places 0:15:23.400 --> 0:15:26.200 in their d n A that's different between those two groups. 0:15:26.520 --> 0:15:28.800 And so we can say that people who have who 0:15:28.800 --> 0:15:31.320 are afraid of heights tend to have this certain genetic 0:15:31.360 --> 0:15:34.000 marker that people who aren't afraid of heights who don't have. 0:15:34.360 --> 0:15:36.120 And then we can tell you that that you may 0:15:36.160 --> 0:15:39.040 have this marker that seems to be associated with being 0:15:39.040 --> 0:15:56.040 afraid of heights. You know, really interesting thing I found 0:15:56.080 --> 0:16:01.240 out my mom has natural degeneration and and my mother 0:16:01.320 --> 0:16:03.640 in law, who believe it or not, Jackie, ever since 0:16:03.680 --> 0:16:06.360 the David and I met back in college over all 0:16:06.480 --> 0:16:09.320 those years, I never had a single cross word with 0:16:09.360 --> 0:16:13.840 his mother or father. Yeah, I'm really really blessed, just 0:16:14.080 --> 0:16:18.440 just so blessed to had them in my life. His 0:16:18.520 --> 0:16:23.400 mother had macular degeneration really badly. Now here's what's interesting. 0:16:23.760 --> 0:16:26.960 I don't show a higher likelihood of getting macular degeneration, 0:16:27.000 --> 0:16:31.160 but my husband does. I haven't told him yet. He's 0:16:31.200 --> 0:16:34.280 kind of like shut down after he found out he 0:16:34.320 --> 0:16:37.760 wasn't Scottish. Okay, so that's a whole another thing. He 0:16:37.960 --> 0:16:40.240 is so convinced he's Scottish. We even bought him a 0:16:40.320 --> 0:16:44.720 kilt and made him wear at one time. Um, he's not. 0:16:45.320 --> 0:16:49.400 He's not Scottish. I think that he's questioning the whole 0:16:50.000 --> 0:16:53.720 oh process because he wants to be Scottish so badly. 0:16:53.800 --> 0:16:57.400 He loves bagpipes, he loves everything about it. But he 0:16:57.680 --> 0:17:00.920 found out that he's a mutt like me and um, 0:17:01.600 --> 0:17:03.800 and he's got a little bit of French in German 0:17:03.880 --> 0:17:07.679 and him, and he was just he was upset when 0:17:07.720 --> 0:17:12.359 he found out our so called thoroughbred dockson was part poodle. Okay. 0:17:12.400 --> 0:17:14.760 He was very disturbed about that. So I haven't been 0:17:14.760 --> 0:17:16.800 able to talk to him about being part French and 0:17:16.880 --> 0:17:19.520 part German. Yet I'm going to save it for just 0:17:19.680 --> 0:17:22.520 the right moment. But you know, another thing I found 0:17:22.520 --> 0:17:27.639 out is that, Um, I knew that I was part Jewish, 0:17:27.840 --> 0:17:31.000 but I didn't know it was Ashkenazi. Now that is 0:17:31.160 --> 0:17:36.200 very significant because there are certain health risks associated with 0:17:36.680 --> 0:17:40.399 being Ashkenazi. Does anybody know the answer to that? What 0:17:40.480 --> 0:17:43.480 are those health risks? Yeah? I can jump in here. Um, 0:17:43.560 --> 0:17:47.879 there's certain populations, whether genetic variants that occur more common, 0:17:48.040 --> 0:17:50.160 as Nazi Jewish is one of those that we see 0:17:50.600 --> 0:17:54.960 certain genetic condition much more common in that population. And 0:17:55.040 --> 0:17:57.760 so one of the ones that we think about is 0:17:58.400 --> 0:18:02.800 the r are um inheriting breast cancer, had a hereditary 0:18:02.800 --> 0:18:06.359 breast cancer and or variating cancer. This frest and hold 0:18:06.400 --> 0:18:14.040 on running that down. Hereditary breast cancer, hereditary a varying cancer. Yes, 0:18:14.119 --> 0:18:18.280 the rday line and r C too, and so individuals 0:18:18.280 --> 0:18:21.880 of oh yeah, just so you know, ladies, Karen Stark's 0:18:22.119 --> 0:18:27.960 breast cancer survivor, go ahead and georr you Oscanazi Karen? 0:18:30.920 --> 0:18:33.920 So you know we're related. Not only did we live 0:18:33.920 --> 0:18:35.880 down the street from each other in New York, now 0:18:35.920 --> 0:18:39.920 we find out we're related. Okay, breast cancer, hereditary breast 0:18:39.920 --> 0:18:43.280 cancretary of varying cancer, the brocka Chaine, and I believe 0:18:43.320 --> 0:18:48.240 tastes lock syndrome, isn't that. Yeah, there's a lot of 0:18:48.280 --> 0:18:51.720 conditions that are autosomal respessive, which is a fancy way 0:18:51.720 --> 0:18:54.360 of saying that kind of you inherited that experience from 0:18:54.359 --> 0:18:57.440 your both room parents, and that can result from the condition. 0:18:57.880 --> 0:19:01.720 And we see more of the like thing in certain populations. 0:19:04.080 --> 0:19:06.080 And so for the r A you're talking about, that 0:19:06.160 --> 0:19:09.840 about one in forty individuals of the Jewish ancestry are 0:19:10.160 --> 0:19:13.760 barriers or habits a variance that greatly increases the risk 0:19:13.880 --> 0:19:18.399 for these certain cancers like breasco various or costee anatic. 0:19:18.880 --> 0:19:21.679 You know, I found out so much about my mom too, guys. 0:19:21.720 --> 0:19:25.920 I found out that she is partially Nigerian. I found 0:19:25.920 --> 0:19:29.359 out so much about mom. What what is that you 0:19:29.359 --> 0:19:31.840 care and start jeffing and go ahead. Yeah. I wanted 0:19:31.880 --> 0:19:34.959 to say, like, if if you get those kind of 0:19:35.000 --> 0:19:38.080 results and they say a potensity to a dist or 0:19:38.840 --> 0:19:43.920 something about the brothogene, it's really important not to be afraid, 0:19:43.960 --> 0:19:47.720 but to go and talk to somebody and go over 0:19:47.720 --> 0:19:50.399 it with your doctor or a genetic counsels like you 0:19:50.480 --> 0:19:52.360 have on the show. Hey, you know what it did 0:19:52.400 --> 0:19:56.240 to me when I found out, um, about the higher 0:19:56.280 --> 0:20:00.680 likelihood of getting type two diabetes. Well, first immediately ordered 0:20:00.720 --> 0:20:04.040 Crispy Kream's and I ate my way through them. Then 0:20:04.119 --> 0:20:08.760 I swore them off. I'm trying. I have one last 0:20:08.800 --> 0:20:16.000 beender before I went on Straight and Narrow. But anyway 0:20:16.200 --> 0:20:19.320 back to twenty three and me, and can we talk 0:20:19.359 --> 0:20:23.920 about security, because um, I found out all sorts of 0:20:23.960 --> 0:20:27.440 things in my line of work. When you talk about 0:20:27.560 --> 0:20:29.720 d n A tists, it's never a good thing. Okay, 0:20:30.160 --> 0:20:33.000 you know it's as related as I'm crying. But with 0:20:33.119 --> 0:20:38.560 twenty three and me, Um, you can now explain this correctly. 0:20:39.080 --> 0:20:43.960 Stacy dett Wilder and Alisa Lehman. You can actually have 0:20:44.160 --> 0:20:48.960 all of your your results destroyed after you get them. 0:20:49.240 --> 0:20:51.600 If you don't want them kept on file, They're destroyed. 0:20:51.640 --> 0:20:57.320 They're gone, like turning off the TV. It's over. It's gone. Um. 0:20:57.400 --> 0:21:00.439 You can have it not shared with the public or 0:21:00.480 --> 0:21:03.320 shared with the public if you want. You can have 0:21:03.440 --> 0:21:05.720 limited parts of it shared with the public or none 0:21:05.720 --> 0:21:08.560 of it shared with the public. Is it is all 0:21:08.600 --> 0:21:12.480 of that right? Alisa and or Stacey. Yeah, that's right, 0:21:12.520 --> 0:21:16.000 and I encourage everyone to check out twenty three and 0:21:16.040 --> 0:21:19.400 me dot com slash privacy because I think you're right 0:21:19.480 --> 0:21:21.720 that a lot of people think about the privacy and 0:21:21.760 --> 0:21:25.400 the security concerns about getting this information. And we want 0:21:25.400 --> 0:21:28.480 people to make an informed choice before they decide to 0:21:28.480 --> 0:21:30.040 do test or not. And so we have a lot 0:21:30.080 --> 0:21:33.360 of information about what is what we do to protect 0:21:33.359 --> 0:21:37.439 your information. So, yes, you can have your sample destroyed, 0:21:37.440 --> 0:21:41.120 your DNA sample that you provide. You can completely delete 0:21:41.119 --> 0:21:43.600 all your information after you after you get it. You 0:21:43.600 --> 0:21:47.520 can download all your information. You can choose UM which 0:21:47.560 --> 0:21:49.760 reports that you want to view or not view, and 0:21:49.880 --> 0:21:52.920 UM within the health reports, you can choose if you 0:21:52.960 --> 0:21:55.800 want to share information with other people on the twenty 0:21:55.800 --> 0:21:59.359 three and me site or with research or not UM, 0:21:59.400 --> 0:22:01.840 and you can use what information is shared. So you 0:22:01.880 --> 0:22:05.719 have a lot of control over who sees your information. 0:22:06.119 --> 0:22:08.239 And we want to make sure that people are you know, 0:22:08.359 --> 0:22:11.919 informed of those choices ahead of time. And our general 0:22:11.960 --> 0:22:15.280 policy is that all of these things are opting into sharing. 0:22:15.680 --> 0:22:17.760 So if you don't do anything, we assume you do 0:22:17.840 --> 0:22:21.160 not want to have your information and shared. Oh that's 0:22:21.160 --> 0:22:24.879 so smart. Guys, what she just said. I just immediately 0:22:24.920 --> 0:22:27.560 compared it to if you're in court and you don't 0:22:27.600 --> 0:22:30.480 interimpl the judges automatically and there's not guilty for you. 0:22:30.720 --> 0:22:33.760 If you don't check any of these boxes, then they 0:22:33.800 --> 0:22:37.960 automatically put it on privacy where you don't share it 0:22:38.160 --> 0:22:42.159 with anyone in any degree. And again you can have 0:22:42.240 --> 0:22:47.560 the whole thing deleted and your tests destroyed if that's 0:22:47.600 --> 0:22:49.800 what you want. Hey, you know what another thing I 0:22:49.800 --> 0:22:53.200 found out? This is so crazy, then I am wait 0:22:53.240 --> 0:22:57.240 for it, Jackie, wait for it. More likely to experience 0:22:57.280 --> 0:23:00.520 here photo bleaching, which means that when you out in 0:23:00.560 --> 0:23:02.879 the sun, your hair turns blonder. See. I told you 0:23:02.960 --> 0:23:05.560 this was natural, and you didn't believe me. You kept saying, 0:23:06.200 --> 0:23:08.360 who did your hair? Or who did not do your hair? 0:23:08.560 --> 0:23:10.880 Can't han't, can't go do your hair. See it's all 0:23:10.920 --> 0:23:13.919 because of the sun. This is natural, right? How do 0:23:14.040 --> 0:23:17.320 they know that? Can Alice or Stacy tell me that 0:23:17.320 --> 0:23:19.720 that is? That is very similar to you know, the 0:23:19.760 --> 0:23:23.480 fear of heights, um, you know, fear of public speaking, 0:23:24.000 --> 0:23:27.240 like preferences like you know, whether you prefer chocolate or 0:23:27.280 --> 0:23:30.480 vanilla ice cream? All of that is you know, comparing 0:23:30.520 --> 0:23:33.120 the DNA as people who who say their hair gets 0:23:33.200 --> 0:23:35.560 lighter in the sun to people whose hair doesn't get 0:23:35.600 --> 0:23:38.480 lighter in the sun, and finding these little places that 0:23:39.040 --> 0:23:41.920 are are different between people who have those different experiences, 0:23:42.000 --> 0:23:44.720 and then again being able to report back to you 0:23:45.200 --> 0:23:47.399 based on your DNA you might be more likely to 0:23:47.760 --> 0:23:51.600 have that hair photo bliefing happen. Listen to this, guys. 0:23:51.600 --> 0:23:54.399 This is what you can learn. Are you prone to 0:23:54.440 --> 0:23:57.720 type two diabetes? If so, what can you do about it? 0:23:58.040 --> 0:24:02.320 Im macular degeneration? What can David and Lucy do about it? 0:24:02.960 --> 0:24:06.800 I found out that I was more acutely, I have 0:24:06.880 --> 0:24:11.240 a more acute odor detection, which is really interesting. Jackie 0:24:11.440 --> 0:24:14.720 Karen start. Remember after COVID, both John, David and I 0:24:14.880 --> 0:24:20.000 lost a sense of smell, and um I first tested 0:24:20.040 --> 0:24:22.840 about midnight. We were up watching Elf, the Christmas movie, 0:24:23.200 --> 0:24:27.359