1 00:00:02,200 --> 00:00:05,199 Speaker 1: If you or maybe your kid has needed a prescription 2 00:00:05,360 --> 00:00:09,800 Speaker 1: for the popular antibiotic amoxicillin lately. You know that's the 3 00:00:10,000 --> 00:00:12,680 Speaker 1: bright pink one, Well, you might have had a hard 4 00:00:12,720 --> 00:00:16,360 Speaker 1: time finding a pharmacy that has it on hand, or 5 00:00:16,440 --> 00:00:20,360 Speaker 1: any number of other generic medications for that matter. Bloomberg's 6 00:00:20,360 --> 00:00:23,400 Speaker 1: Ike Sweatlts reports that some of the most in demand 7 00:00:23,480 --> 00:00:27,200 Speaker 1: generics in the US are increasingly in short supply. 8 00:00:27,880 --> 00:00:30,680 Speaker 2: What's significant now is that there's a lot of shortages 9 00:00:30,760 --> 00:00:33,839 Speaker 2: in a lot of different areas that are all affecting patients. 10 00:00:33,840 --> 00:00:35,840 Speaker 2: So you have the cancer drugs, you have the antibiotics, 11 00:00:35,840 --> 00:00:39,400 Speaker 2: you have the ADHD medicines. Each of these areas has 12 00:00:39,479 --> 00:00:43,440 Speaker 2: seen issues and challenges before. What's unique now is sort 13 00:00:43,479 --> 00:00:44,920 Speaker 2: of all happening at the same time. 14 00:00:45,560 --> 00:00:49,800 Speaker 1: Ike's here to explain why that is, and Health Security 15 00:00:49,880 --> 00:00:52,960 Speaker 1: reporter Riley Griffin is back to tell us what the 16 00:00:53,120 --> 00:00:56,360 Speaker 1: US government is doing to try to fix this growing problem. 17 00:00:56,840 --> 00:00:58,880 Speaker 3: But it remains to be seen whether or not they 18 00:00:58,880 --> 00:01:02,720 Speaker 3: will achieve something at the scale of say the Chips Act, 19 00:01:02,960 --> 00:01:06,400 Speaker 3: which was about bringing chips production back here to the 20 00:01:06,480 --> 00:01:10,319 Speaker 3: United States. But we have not seen a Chips for pharma. 21 00:01:10,440 --> 00:01:13,320 Speaker 3: Despite people advocating for it, and despite folks at the 22 00:01:13,360 --> 00:01:17,520 Speaker 3: White House really thinking critically about all the different ways 23 00:01:17,560 --> 00:01:25,000 Speaker 3: to approach this problem. 24 00:01:25,319 --> 00:01:36,319 Speaker 1: I'm Wescasova today on the big take the generic drug dilemma. 25 00:01:38,640 --> 00:01:41,160 Speaker 1: Let me just start by asking you the big question, 26 00:01:41,240 --> 00:01:45,200 Speaker 1: what is causing this shortage of generic drugs in the US. 27 00:01:46,040 --> 00:01:49,559 Speaker 2: There have been shortages of generic drugs in the US 28 00:01:49,760 --> 00:01:54,960 Speaker 2: really for over a decade. There are individual events that 29 00:01:55,040 --> 00:01:59,280 Speaker 2: might prompt each shortage, whether it's a hurricane or a 30 00:01:59,280 --> 00:02:02,400 Speaker 2: plant that has to shut down or stop manufacturing because 31 00:02:02,520 --> 00:02:05,520 Speaker 2: there was some safety or quality issue. 32 00:02:05,160 --> 00:02:05,880 Speaker 4: With the drugs. 33 00:02:06,200 --> 00:02:09,200 Speaker 2: But behind all of those is the fact that a 34 00:02:09,320 --> 00:02:13,359 Speaker 2: lot of generic drugs don't make a lot of money, 35 00:02:13,440 --> 00:02:16,240 Speaker 2: if any money at all, for the manufacturers. And if 36 00:02:16,280 --> 00:02:19,000 Speaker 2: you have a product that doesn't make a lot of money, 37 00:02:19,160 --> 00:02:24,120 Speaker 2: there's not a huge financial incentive to maintain a robust, 38 00:02:24,360 --> 00:02:29,520 Speaker 2: reliable supply chain with a lot of extra empty manufacturing 39 00:02:29,520 --> 00:02:33,120 Speaker 2: capacity that you can quickly use when something goes wrong. 40 00:02:34,760 --> 00:02:37,360 Speaker 1: Generic drugs have been around for a long time and 41 00:02:37,480 --> 00:02:40,200 Speaker 1: manufacturers have been able to turn a profit making them. 42 00:02:40,440 --> 00:02:44,600 Speaker 1: Why have they become unprofitable now to the point where 43 00:02:44,720 --> 00:02:46,280 Speaker 1: there are shortages. 44 00:02:46,560 --> 00:02:50,280 Speaker 2: When the idea of generic drugs was introduced. You know, 45 00:02:50,320 --> 00:02:52,960 Speaker 2: it was supposed to be that the company that invented 46 00:02:53,000 --> 00:02:55,320 Speaker 2: a medicine was going to get some sort of patent 47 00:02:55,320 --> 00:02:56,600 Speaker 2: protection on it for a little while. 48 00:02:57,080 --> 00:02:59,440 Speaker 4: They make a lot of money during that time. 49 00:02:59,240 --> 00:03:03,080 Speaker 2: To recoup their research and development costs, and then the 50 00:03:03,160 --> 00:03:06,000 Speaker 2: drug goes generic. A lot of other companies can enter 51 00:03:06,000 --> 00:03:08,799 Speaker 2: the market and produce their own versions at a much 52 00:03:08,800 --> 00:03:11,919 Speaker 2: lower cost of patients. The whole idea behind generic drugs 53 00:03:11,960 --> 00:03:14,160 Speaker 2: is that they're supposed to be cheaper for patients. 54 00:03:14,639 --> 00:03:16,480 Speaker 4: The problem comes when. 55 00:03:16,639 --> 00:03:19,680 Speaker 2: The cost of the generic drugs falls so low that 56 00:03:19,760 --> 00:03:24,079 Speaker 2: their manufacturers can't cover their cost of production. And there 57 00:03:24,080 --> 00:03:26,799 Speaker 2: are a lot of reasons why prices and cost of 58 00:03:26,840 --> 00:03:29,720 Speaker 2: generic drugs have been going down and down. Partially, it's 59 00:03:29,720 --> 00:03:33,360 Speaker 2: sort of baked into the system. So all generic amoxicillin, 60 00:03:33,440 --> 00:03:36,240 Speaker 2: for example, this antibiotic the most popular antibiotic in the 61 00:03:36,320 --> 00:03:39,880 Speaker 2: United States. They're all supposed to be equivalent to each other. 62 00:03:39,920 --> 00:03:41,960 Speaker 2: That's what the FDA says. You go into a pharmacy, 63 00:03:41,960 --> 00:03:44,680 Speaker 2: you fill a prescription for amoxicillin. You don't ask for 64 00:03:44,840 --> 00:03:47,640 Speaker 2: a ma oxiscillin from this manufacturer that manufacturer. You just 65 00:03:47,680 --> 00:03:50,440 Speaker 2: fill the prescription. They give you whatever generic they happen 66 00:03:50,480 --> 00:03:53,800 Speaker 2: to have. So the only thing that generic drugs are 67 00:03:53,800 --> 00:03:57,960 Speaker 2: really competing on is on the price. There's also consolidation 68 00:03:58,120 --> 00:04:03,640 Speaker 2: among the companies that per chis generic drugs, especially for pharmacies. 69 00:04:04,200 --> 00:04:06,520 Speaker 4: So there's basically. 70 00:04:06,200 --> 00:04:10,960 Speaker 2: Three or four large buying groups that buy about ninety 71 00:04:11,040 --> 00:04:15,000 Speaker 2: percent of all of the generic drugs that are dispensed 72 00:04:15,120 --> 00:04:19,560 Speaker 2: in retail pharmacies you know, CVS Walgreens in the United States, 73 00:04:19,880 --> 00:04:22,479 Speaker 2: And because there's only a handful of them, they have 74 00:04:22,560 --> 00:04:25,119 Speaker 2: a lot of power in the market, and that power 75 00:04:25,360 --> 00:04:28,560 Speaker 2: helps drive down the cost and price of those drugs. 76 00:04:29,080 --> 00:04:31,520 Speaker 1: Like like you mentioned, amoxicillin is one of the drugs 77 00:04:31,560 --> 00:04:34,120 Speaker 1: that's in short supply. I think anyone who's had a 78 00:04:34,200 --> 00:04:37,000 Speaker 1: kid or was a kid knows all about a maxicillin. 79 00:04:37,200 --> 00:04:40,120 Speaker 1: It's so widely used. But what other medicines are also 80 00:04:40,200 --> 00:04:41,000 Speaker 1: in short supply. 81 00:04:41,800 --> 00:04:45,160 Speaker 2: There's a lot of cancer drugs, chemotherapy, medicines that are 82 00:04:45,160 --> 00:04:48,320 Speaker 2: in short supply right now. That's one big category. Then 83 00:04:48,360 --> 00:04:51,159 Speaker 2: there's the drugs that you pick up at the pharmacy, antibiotics, 84 00:04:51,320 --> 00:04:55,200 Speaker 2: a lot of medicines for ADHD, other antibiotics other than 85 00:04:55,240 --> 00:04:57,600 Speaker 2: a maxicillin. You know, the latest data that we have 86 00:04:57,800 --> 00:05:01,039 Speaker 2: from the University of Utah's service, there tracking three hundred 87 00:05:01,080 --> 00:05:04,040 Speaker 2: and five drugs that are in short supply. That's the 88 00:05:04,120 --> 00:05:08,520 Speaker 2: highest it's been since twenty fourteen. But what's significant now 89 00:05:08,600 --> 00:05:10,800 Speaker 2: is that there's a lot of shortages in a lot 90 00:05:10,839 --> 00:05:13,640 Speaker 2: of different areas that are all affecting patients. So you 91 00:05:13,680 --> 00:05:15,599 Speaker 2: have the cancer drugs, you have the antibiotics, you have 92 00:05:15,640 --> 00:05:19,919 Speaker 2: the ADHD medicines. Each of these areas has seen issues 93 00:05:19,960 --> 00:05:23,400 Speaker 2: and challenges before. What's unique now is sort of all 94 00:05:23,440 --> 00:05:24,520 Speaker 2: happening at the same time. 95 00:05:25,360 --> 00:05:27,800 Speaker 1: And you report that part of the challenge for US 96 00:05:27,839 --> 00:05:32,520 Speaker 1: manufacturers is increased competition from overseas, where they're able to 97 00:05:32,760 --> 00:05:36,320 Speaker 1: get the ingredients and manufacture the drugs much more cheaply. 98 00:05:37,040 --> 00:05:41,279 Speaker 2: Yeah, there are different labor costs, there's different energy costs. 99 00:05:41,640 --> 00:05:44,640 Speaker 2: That's sort of been happening, i would say over the 100 00:05:44,680 --> 00:05:48,279 Speaker 2: past few decades. That's not something that's just new right now, 101 00:05:48,720 --> 00:05:52,240 Speaker 2: but that is definitely something that has on one hand, 102 00:05:52,320 --> 00:05:56,000 Speaker 2: made a lot of these medicines more accessible physically and 103 00:05:56,040 --> 00:05:58,760 Speaker 2: financially for people all around the world. It's also made 104 00:05:58,760 --> 00:06:01,960 Speaker 2: it more difficult for some manuft as to keep up 105 00:06:02,000 --> 00:06:05,360 Speaker 2: financially and keep producing the drugs, and. 106 00:06:05,320 --> 00:06:07,359 Speaker 1: So why is it important that these drugs have to 107 00:06:07,360 --> 00:06:09,960 Speaker 1: come from US makers. Why can't we just shift to 108 00:06:10,360 --> 00:06:14,440 Speaker 1: buying more foreign antibiotics and other drugs. 109 00:06:15,120 --> 00:06:17,919 Speaker 2: Well, that depends on who you ask, So some people 110 00:06:17,920 --> 00:06:19,520 Speaker 2: would say that that's totally fine. 111 00:06:19,560 --> 00:06:21,560 Speaker 4: You know, that's just part of the globalized supply chain. 112 00:06:21,960 --> 00:06:24,320 Speaker 2: Things are made in different places, and what we really 113 00:06:24,360 --> 00:06:28,360 Speaker 2: need to do is work to reduce the barriers from 114 00:06:28,440 --> 00:06:31,839 Speaker 2: getting the medicines from point A to point B. Another 115 00:06:31,920 --> 00:06:34,000 Speaker 2: argument is that it's important for countries to be able 116 00:06:34,040 --> 00:06:36,480 Speaker 2: to provide medicines for the health and well being of 117 00:06:36,520 --> 00:06:40,839 Speaker 2: the people who live there and in times of international 118 00:06:40,880 --> 00:06:45,520 Speaker 2: conflict or international crisis global pandemic, for example, we saw 119 00:06:45,800 --> 00:06:50,200 Speaker 2: earlier in COVID some countries restricting the export of medical products, 120 00:06:50,760 --> 00:06:55,400 Speaker 2: and so having medicines and having the ingredients to make 121 00:06:55,400 --> 00:06:58,760 Speaker 2: those medicines available in the country might be helpful in 122 00:06:58,760 --> 00:07:03,080 Speaker 2: that situation, or having policies that would allow those products 123 00:07:03,080 --> 00:07:06,040 Speaker 2: to be bought and sold even in those more extreme situations. 124 00:07:06,839 --> 00:07:12,720 Speaker 2: More domestic manufacturing of generic drugs is not something that 125 00:07:12,840 --> 00:07:16,080 Speaker 2: everyone is calling for as a solution to these drug shortages. 126 00:07:16,400 --> 00:07:20,520 Speaker 2: In fact, people are pointing out that domestic US manufacturing 127 00:07:20,520 --> 00:07:24,360 Speaker 2: plants can have the same problems that plants outside the 128 00:07:24,440 --> 00:07:25,320 Speaker 2: United States can have. 129 00:07:26,280 --> 00:07:29,200 Speaker 1: And so what are the practical effects of having these shortages. 130 00:07:29,720 --> 00:07:31,880 Speaker 1: Do you have to just switch to a different kind 131 00:07:31,880 --> 00:07:34,440 Speaker 1: of say, antibiotic, or are you just able to find it 132 00:07:34,480 --> 00:07:36,360 Speaker 1: overseas even if you aren't able to find it in 133 00:07:36,400 --> 00:07:36,880 Speaker 1: the US. 134 00:07:37,720 --> 00:07:40,400 Speaker 4: So it depends on what sort of medicine it is. 135 00:07:40,680 --> 00:07:45,680 Speaker 2: So for antibiotics, there are other antibiotics other than amoxicillin, 136 00:07:45,760 --> 00:07:50,360 Speaker 2: for example. The problem is last year, when a lot 137 00:07:50,360 --> 00:07:53,880 Speaker 2: of these maxicillin shortages started, the companies that make those 138 00:07:54,000 --> 00:07:58,000 Speaker 2: other antibiotics were not anticipating in a maxicillin shortage that 139 00:07:58,000 --> 00:08:00,320 Speaker 2: would then lead to a run on their products. So 140 00:08:00,760 --> 00:08:04,920 Speaker 2: when patients couldn't find a ma oxicillin, their doctor might 141 00:08:04,920 --> 00:08:07,520 Speaker 2: give them a prescription for another type of antibiotics, say 142 00:08:07,560 --> 00:08:10,720 Speaker 2: a different kind of penicillin. But then people started filling 143 00:08:10,720 --> 00:08:13,600 Speaker 2: those prescriptions for all those penicillins. After that, then there 144 00:08:13,680 --> 00:08:16,520 Speaker 2: was a diminished supply of those penicillins, and one of 145 00:08:16,520 --> 00:08:21,840 Speaker 2: those is basically the only treatment for pregnant people with syphilis. 146 00:08:22,040 --> 00:08:26,160 Speaker 2: And now that penicillin is a lot harder to find 147 00:08:26,520 --> 00:08:29,560 Speaker 2: and making it more difficult to treat those folks. So 148 00:08:29,600 --> 00:08:31,760 Speaker 2: there's sort of those like knock on effects of yeah, 149 00:08:31,800 --> 00:08:34,480 Speaker 2: maybe in an individual case you can fill the prescription 150 00:08:34,520 --> 00:08:38,000 Speaker 2: with something else, but that leads to a shortage down 151 00:08:38,080 --> 00:08:41,320 Speaker 2: the road. There's another problem, especially with antibiotics, which is 152 00:08:41,760 --> 00:08:43,000 Speaker 2: that you're really. 153 00:08:42,800 --> 00:08:45,840 Speaker 4: Supposed to use the most specific. 154 00:08:45,320 --> 00:08:48,440 Speaker 2: Antibiotic that you can because you want the antibiotic to 155 00:08:48,600 --> 00:08:50,559 Speaker 2: kill the bacteria that you've got. 156 00:08:51,160 --> 00:08:52,520 Speaker 4: You don't really want it to do anything else. 157 00:08:52,920 --> 00:08:56,520 Speaker 2: If you use sort of a general antibiotic that's maybe 158 00:08:56,559 --> 00:08:59,679 Speaker 2: not quite as good at killing that particular bacteria, what 159 00:08:59,679 --> 00:09:04,640 Speaker 2: happens is the bacteria will develop resistance to that antabatic, 160 00:09:05,000 --> 00:09:07,920 Speaker 2: and then that antibatic becomes much less effective in the future. 161 00:09:10,080 --> 00:09:13,040 Speaker 1: In your reporting, you write about an American company called 162 00:09:13,200 --> 00:09:16,800 Speaker 1: US Antibiotics, and they're facing a lot of the things 163 00:09:16,800 --> 00:09:19,559 Speaker 1: you're describing here. Can you tell us about that company? 164 00:09:19,840 --> 00:09:22,280 Speaker 2: So that company started a few years ago when they 165 00:09:22,320 --> 00:09:26,720 Speaker 2: purchased what at the time was the only plant in 166 00:09:26,760 --> 00:09:30,400 Speaker 2: the United States making a maxicillin. That plant used to 167 00:09:30,440 --> 00:09:33,640 Speaker 2: make enough a maxicillin for everyone in the United States 168 00:09:33,679 --> 00:09:37,480 Speaker 2: who needed it. It was opened in the seventies in Bristol, Tennessee. 169 00:09:37,960 --> 00:09:40,800 Speaker 2: You know what, its peak had five hundred or so employees. 170 00:09:41,280 --> 00:09:45,800 Speaker 2: Back then, this was a brand product, more financially lucrative. 171 00:09:46,280 --> 00:09:49,640 Speaker 2: The drugs went generic. The plant changed hands a few 172 00:09:49,640 --> 00:09:53,080 Speaker 2: times over the past fifteen years, and the company that 173 00:09:53,120 --> 00:09:55,880 Speaker 2: owned it most recently before US Antabatics a few years 174 00:09:55,880 --> 00:09:59,760 Speaker 2: ago went into bankruptcy and US Antibiotics bought the plant 175 00:09:59,760 --> 00:10:03,520 Speaker 2: out that they knew that this was going to be 176 00:10:03,920 --> 00:10:08,040 Speaker 2: a challenge. The company that bought it is a subsidiary 177 00:10:08,160 --> 00:10:11,600 Speaker 2: of Jackson Healthcare, which is mostly a medical staffing company. 178 00:10:11,880 --> 00:10:14,960 Speaker 2: And Rick Jackson, who runs Jackson Healthcare, told me he 179 00:10:15,040 --> 00:10:18,040 Speaker 2: bought this sort of more out of what he felt 180 00:10:18,080 --> 00:10:20,080 Speaker 2: was like a civic duty to keep it open and 181 00:10:20,120 --> 00:10:22,840 Speaker 2: keep it running. He bought this plant knowing that it 182 00:10:22,920 --> 00:10:25,920 Speaker 2: might not be the best business opportunity, but he wanted 183 00:10:25,920 --> 00:10:28,720 Speaker 2: to make sure that a marxicillin was going to continue 184 00:10:28,760 --> 00:10:30,360 Speaker 2: to be produced in the United States. 185 00:10:30,960 --> 00:10:32,480 Speaker 1: And how'd that work out for him? 186 00:10:32,800 --> 00:10:35,360 Speaker 2: Well, so far, the plant, you know, it's still running. 187 00:10:35,720 --> 00:10:38,120 Speaker 2: He said that it's losing a lot of money, and 188 00:10:38,200 --> 00:10:42,160 Speaker 2: he is hoping that the US government will commit to 189 00:10:42,200 --> 00:10:45,720 Speaker 2: purchasing drugs from there to sort of provide a dedicated 190 00:10:45,720 --> 00:10:48,679 Speaker 2: revenue stream and allow him to keep it open. 191 00:10:49,000 --> 00:10:51,360 Speaker 4: And the future of this plant really hinges on that. 192 00:10:52,160 --> 00:10:54,120 Speaker 1: And you went to see this plant, where was it? 193 00:10:54,200 --> 00:10:56,600 Speaker 4: Like? It's a giant facility. 194 00:10:56,640 --> 00:10:59,839 Speaker 2: I think it's three hundred and ninety four thousand square 195 00:11:00,480 --> 00:11:03,360 Speaker 2: I've been writing for months about how patients hadn't been 196 00:11:03,360 --> 00:11:05,680 Speaker 2: able to fill prescriptions, and I go and see a 197 00:11:05,760 --> 00:11:09,800 Speaker 2: huge amount of the active pharmaceutical ingredient in the warehouse there. 198 00:11:10,240 --> 00:11:13,240 Speaker 2: It was a pretty empty place compared to what it 199 00:11:13,280 --> 00:11:15,480 Speaker 2: could be. There was equipment there that was just sitting 200 00:11:15,559 --> 00:11:18,280 Speaker 2: under plastic. It wasn't being used anymore. There were areas 201 00:11:18,320 --> 00:11:21,040 Speaker 2: of the plant that had been closed off a while ago. 202 00:11:21,600 --> 00:11:23,839 Speaker 2: This is a highly regulated field and there's a lot 203 00:11:23,880 --> 00:11:26,160 Speaker 2: of things you have to do in exactly the right 204 00:11:26,200 --> 00:11:29,360 Speaker 2: way all the time, and that costs money, and that 205 00:11:29,400 --> 00:11:30,640 Speaker 2: takes time to train people to do. 206 00:11:32,120 --> 00:11:35,680 Speaker 1: So if they're losing money, how can they continue to 207 00:11:35,720 --> 00:11:36,679 Speaker 1: stay in business? 208 00:11:37,320 --> 00:11:41,120 Speaker 2: Rick Jackson Jackson Healthcare said he's providing funds for this, 209 00:11:41,240 --> 00:11:44,000 Speaker 2: but he's not going to subsidize it forever. So I 210 00:11:44,040 --> 00:11:47,840 Speaker 2: think that the future of the plant is up to 211 00:11:48,480 --> 00:11:50,920 Speaker 2: how much money they're able to make selling to the 212 00:11:50,920 --> 00:11:56,120 Speaker 2: government or selling to drug distributors in the commercial market. 213 00:11:56,280 --> 00:11:59,080 Speaker 1: After the break. Is the US the only country facing 214 00:11:59,200 --> 00:12:08,880 Speaker 1: this drug shortage problem? We hear a lot of these 215 00:12:08,960 --> 00:12:12,679 Speaker 1: days about the Biden administrations push to bring manufacturing back 216 00:12:12,720 --> 00:12:17,240 Speaker 1: to the US computer chips, electric vehicles, and batteries. Are 217 00:12:17,280 --> 00:12:20,160 Speaker 1: there any incentives like this where the US government is 218 00:12:20,160 --> 00:12:23,960 Speaker 1: giving money to pharmaceutical companies drug manufacturers to make these 219 00:12:24,040 --> 00:12:25,560 Speaker 1: kinds of drugs that are in short supply. 220 00:12:26,360 --> 00:12:26,640 Speaker 4: Yeah. 221 00:12:26,720 --> 00:12:33,559 Speaker 2: The Biden administration has said that domestic production of pharmaceuticals, 222 00:12:33,559 --> 00:12:37,679 Speaker 2: of medicines, and of the raw ingredients are critical. When 223 00:12:37,720 --> 00:12:41,559 Speaker 2: they announced the Infrastructure Plan several years ago, talking about 224 00:12:41,840 --> 00:12:45,960 Speaker 2: the need for more support for semiconductors for electric vehicle batteries, 225 00:12:46,320 --> 00:12:50,800 Speaker 2: they included pharmaceuticals and medicines in that push. We haven't 226 00:12:50,920 --> 00:12:55,280 Speaker 2: yet seen the large, multi billion dollar subsidy packages coming 227 00:12:55,280 --> 00:12:57,240 Speaker 2: out of Congress to support that in a way that 228 00:12:57,280 --> 00:13:00,600 Speaker 2: we have for batteries and forced conductors. 229 00:13:00,880 --> 00:13:01,400 Speaker 4: I've talked to. 230 00:13:01,320 --> 00:13:05,160 Speaker 2: Folks about this, and one reason people have given is 231 00:13:05,200 --> 00:13:11,080 Speaker 2: that it is politically unpopular to support the drug industry. 232 00:13:11,440 --> 00:13:14,880 Speaker 2: And there's been a lot of attention over the last 233 00:13:14,920 --> 00:13:19,400 Speaker 2: several years on high drug prices, often those high drug 234 00:13:19,440 --> 00:13:23,440 Speaker 2: prices are brand medicines protected by patents. 235 00:13:23,840 --> 00:13:27,280 Speaker 4: New drugs or maybe old drugs, they're still protected by patents. 236 00:13:27,520 --> 00:13:30,680 Speaker 2: So politicians have been doing a lot to try to 237 00:13:30,760 --> 00:13:34,240 Speaker 2: reduce the cost of health care. Healthcare is incredibly expensive 238 00:13:34,240 --> 00:13:36,280 Speaker 2: and it might not look very good for a politician 239 00:13:36,320 --> 00:13:39,120 Speaker 2: to stand up and say, Americans, you should be paying 240 00:13:39,160 --> 00:13:42,400 Speaker 2: more for your medicines. And that makes it difficult to 241 00:13:42,920 --> 00:13:48,079 Speaker 2: get money to these manufacturers of generic drugs. So making 242 00:13:48,120 --> 00:13:50,520 Speaker 2: a lot of generic drugs in the United States would 243 00:13:50,559 --> 00:13:53,480 Speaker 2: cost more than making them outside of the United States, 244 00:13:53,679 --> 00:13:56,600 Speaker 2: and that money's got to come from somewhere. It could 245 00:13:56,600 --> 00:14:00,880 Speaker 2: come from patients paying higher insurance prema, that could come 246 00:14:00,920 --> 00:14:03,320 Speaker 2: from hospitals paying more for the drugs. It could come 247 00:14:03,360 --> 00:14:04,679 Speaker 2: from the government subsidizing it. 248 00:14:05,400 --> 00:14:07,360 Speaker 1: If the US does decide to spend some of this 249 00:14:07,400 --> 00:14:10,800 Speaker 1: money to give incentives to US manufacturers to make these 250 00:14:10,840 --> 00:14:14,319 Speaker 1: drugs in short supply, would that actually help ease the shortage. 251 00:14:15,120 --> 00:14:19,520 Speaker 2: So there are some folks who are trying to establish 252 00:14:19,840 --> 00:14:22,920 Speaker 2: manufacturing plants here and they say, we just need some 253 00:14:23,000 --> 00:14:25,040 Speaker 2: money from the government to sort of get this going, 254 00:14:25,320 --> 00:14:27,000 Speaker 2: and then once we have it going, then we can 255 00:14:27,040 --> 00:14:30,160 Speaker 2: sustain it. I think folks are worried about the government 256 00:14:30,240 --> 00:14:32,640 Speaker 2: just sort of spending a lot of money on a maxicillin, Like, 257 00:14:32,720 --> 00:14:35,280 Speaker 2: right now, here's this acute problem. The government's just going 258 00:14:35,320 --> 00:14:37,200 Speaker 2: to put all this money into it, and that might 259 00:14:37,280 --> 00:14:39,960 Speaker 2: not have the long term. 260 00:14:39,720 --> 00:14:40,920 Speaker 4: Impact people are looking for. 261 00:14:41,240 --> 00:14:44,240 Speaker 2: But I think that people are still actively debating a 262 00:14:44,240 --> 00:14:48,480 Speaker 2: lot of these proposals, and that Congress hasn't passed any legislation. 263 00:14:48,720 --> 00:14:51,080 Speaker 2: There haven't really been any big changes in the last 264 00:14:51,200 --> 00:14:51,880 Speaker 2: year or so on. 265 00:14:51,960 --> 00:14:56,200 Speaker 1: This is the US the only country that's suffering with 266 00:14:56,240 --> 00:14:59,240 Speaker 1: these kinds of shortages. What about countries in Europe, Asia 267 00:14:59,240 --> 00:14:59,880 Speaker 1: and elsewhere. 268 00:15:00,320 --> 00:15:01,880 Speaker 4: There are shortages all over the place. 269 00:15:02,240 --> 00:15:04,680 Speaker 2: Other countries in Europe have been spending money to try 270 00:15:04,680 --> 00:15:07,320 Speaker 2: and boost domestic production. And I think also important to 271 00:15:07,320 --> 00:15:10,640 Speaker 2: remember a lot of these medicines are just not available 272 00:15:10,880 --> 00:15:13,120 Speaker 2: in many parts of the world, So I think that's 273 00:15:13,120 --> 00:15:16,040 Speaker 2: an important point too, and something that low cost generic 274 00:15:16,120 --> 00:15:18,760 Speaker 2: drugs have been really good for getting medicines to places 275 00:15:18,800 --> 00:15:20,760 Speaker 2: that otherwise might not have them period. 276 00:15:21,440 --> 00:15:23,960 Speaker 1: Iik, you're watching this pretty closely as you continue to 277 00:15:24,040 --> 00:15:25,840 Speaker 1: report in the story. What are you looking for? 278 00:15:26,720 --> 00:15:30,400 Speaker 2: I am curious what the US government is going to 279 00:15:30,400 --> 00:15:34,040 Speaker 2: do and what's going to make this different than situations 280 00:15:34,080 --> 00:15:37,400 Speaker 2: we saw ten fifteen years ago. There was a big 281 00:15:37,440 --> 00:15:41,520 Speaker 2: shortage of cancer drugs. Back eleven twelve years ago or so, 282 00:15:41,840 --> 00:15:45,280 Speaker 2: there were congressional hearings, there was an executive order, there 283 00:15:45,440 --> 00:15:46,560 Speaker 2: was political attention. 284 00:15:47,120 --> 00:15:48,440 Speaker 4: Now we're seeing it again. 285 00:15:48,800 --> 00:15:52,560 Speaker 2: Right before the COVID pandemic, the FDA put out a 286 00:15:52,640 --> 00:15:55,240 Speaker 2: report looking at some of the root causes of drug shortages, 287 00:15:55,440 --> 00:15:57,600 Speaker 2: and a number of things identified in that report were 288 00:15:57,880 --> 00:16:01,600 Speaker 2: economic issues. And the FDA, who regulates the safety and 289 00:16:01,600 --> 00:16:05,360 Speaker 2: effectiveness of medicines, it's not going in and setting prices 290 00:16:05,360 --> 00:16:05,920 Speaker 2: for drugs. 291 00:16:06,160 --> 00:16:07,680 Speaker 4: I guess I'm curious what's going to be different this 292 00:16:07,720 --> 00:16:08,240 Speaker 4: time around? 293 00:16:09,040 --> 00:16:11,160 Speaker 1: Hike, thanks so much for coming on the show. 294 00:16:11,640 --> 00:16:12,440 Speaker 4: Thanks for having me. 295 00:16:15,320 --> 00:16:17,520 Speaker 1: Now let's hear what, if anything, can be done to 296 00:16:17,680 --> 00:16:23,440 Speaker 1: ease these shortages. Riley Griffin is Bloomberg's health security reporter. Riley, 297 00:16:23,480 --> 00:16:24,360 Speaker 1: it's good to see again. 298 00:16:24,560 --> 00:16:25,280 Speaker 3: Thanks for having me. 299 00:16:25,360 --> 00:16:28,480 Speaker 1: Wes, So maybe you can paint us a picture of 300 00:16:28,560 --> 00:16:31,480 Speaker 1: what the I guess you'd call it global economy for 301 00:16:31,560 --> 00:16:32,800 Speaker 1: generic drugs. 302 00:16:32,480 --> 00:16:35,680 Speaker 3: Looks like the Food and Drug Administration, our regulator here 303 00:16:35,680 --> 00:16:38,480 Speaker 3: in the US, overseas, the safety of more than two 304 00:16:38,560 --> 00:16:42,320 Speaker 3: point one trillion worth of food, tobacco, and medical products 305 00:16:42,440 --> 00:16:45,480 Speaker 3: produced in the US and abroad, and these sectors account 306 00:16:45,480 --> 00:16:49,120 Speaker 3: for one fifth of the nation's economic activity. Just picture 307 00:16:49,120 --> 00:16:51,880 Speaker 3: that for a moment, a regulator that oversees one fifth 308 00:16:52,240 --> 00:16:55,280 Speaker 3: of the nation's economic activity. So the problem is, of course, 309 00:16:55,320 --> 00:16:58,240 Speaker 3: that not all these pharmaceutical products are made in the US, 310 00:16:58,800 --> 00:17:02,400 Speaker 3: and it becomes increasingly difficult to do that oversight work 311 00:17:02,480 --> 00:17:05,240 Speaker 3: of products coming in for abroad. So I'll share some 312 00:17:05,359 --> 00:17:07,520 Speaker 3: data with you straight from the mouth of the FDA. 313 00:17:08,359 --> 00:17:11,679 Speaker 3: Seventy one percent of US biologic sales that kind of 314 00:17:11,680 --> 00:17:15,480 Speaker 3: more complex drug are actually imports. These aren't the typical 315 00:17:15,520 --> 00:17:18,159 Speaker 3: pills in your medicine cabinet, but the complex medicines you 316 00:17:18,200 --> 00:17:21,879 Speaker 3: often get in an injection developed from blood, proteins, viruses, 317 00:17:22,400 --> 00:17:26,920 Speaker 3: or living organisms. Seventy eight percent of manufacturers that make 318 00:17:27,040 --> 00:17:31,560 Speaker 3: active pharmaceutical ingredients are located outside of the United States. 319 00:17:32,080 --> 00:17:34,600 Speaker 3: And these are the materials that allow a drug to 320 00:17:34,720 --> 00:17:37,960 Speaker 3: have the desired effect in the body. It's the part 321 00:17:37,960 --> 00:17:40,560 Speaker 3: of the recipe that really makes the drug work. And 322 00:17:40,680 --> 00:17:44,440 Speaker 3: back in twenty nineteen, about one fifth of API manufacturers 323 00:17:44,440 --> 00:17:47,800 Speaker 3: were in India and thirteen percent were in China, but 324 00:17:47,880 --> 00:17:51,439 Speaker 3: that's likely to have increased since then. India's pharmaceutical industry, 325 00:17:51,440 --> 00:17:55,640 Speaker 3: for example, is only growing. It's the world's largest producer 326 00:17:55,800 --> 00:17:59,680 Speaker 3: of generic drugs, and that's a fifty billion dollar industry 327 00:18:00,000 --> 00:18:00,440 Speaker 3: over there. 328 00:18:01,160 --> 00:18:04,000 Speaker 1: So given all of that and the shift of drug 329 00:18:04,080 --> 00:18:07,600 Speaker 1: manufacturing to Asia where they're able to make more of 330 00:18:07,640 --> 00:18:09,800 Speaker 1: it for cheaper, why are we having shortages? 331 00:18:10,640 --> 00:18:13,960 Speaker 3: There are a lot of different reasons for drug shortages. 332 00:18:14,400 --> 00:18:17,880 Speaker 3: The primary one, FDA says six and ten drug shortages 333 00:18:17,920 --> 00:18:22,720 Speaker 3: are caused by quality problems, So that might be a 334 00:18:22,760 --> 00:18:26,399 Speaker 3: contamination and a batch or a lack of appropriate active 335 00:18:26,400 --> 00:18:29,080 Speaker 3: pharmaceutical ingredient. There are a lot of different reasons that 336 00:18:29,119 --> 00:18:33,080 Speaker 3: can spur a manufacturing or quality issue, but that is 337 00:18:33,119 --> 00:18:34,000 Speaker 3: the biggest driver. 338 00:18:35,000 --> 00:18:36,879 Speaker 1: And so when a drug has to be pulled out 339 00:18:36,920 --> 00:18:40,400 Speaker 1: the market because of a quality problem, do they relatively 340 00:18:40,480 --> 00:18:42,600 Speaker 1: quickly fix it and get it back on the shelves? 341 00:18:43,359 --> 00:18:45,639 Speaker 3: No wes. A year and a half is the average 342 00:18:45,720 --> 00:18:48,560 Speaker 3: duration of a drug shortage. According to a Homeland Security 343 00:18:48,600 --> 00:18:52,200 Speaker 3: and Government Affairs Committee report, sixty percent of drug shortages 344 00:18:52,480 --> 00:18:56,360 Speaker 3: are caused by underlying quality or manufacturing issues. If there 345 00:18:56,440 --> 00:18:58,560 Speaker 3: is something so severe that a product has to be 346 00:18:58,600 --> 00:19:00,760 Speaker 3: pulled from the market, it could be a while before 347 00:19:00,760 --> 00:19:05,520 Speaker 3: a shortage is resolved. Another reason for shortages is outright discontinuation. 348 00:19:05,840 --> 00:19:09,439 Speaker 3: So say you used to have five producers of a 349 00:19:09,480 --> 00:19:13,280 Speaker 3: specific generic drug and two of them get out of 350 00:19:13,280 --> 00:19:16,640 Speaker 3: that business because it's no longer profitable for them. That's 351 00:19:16,680 --> 00:19:19,800 Speaker 3: fewer production to meet the demand that exists. And then 352 00:19:19,840 --> 00:19:23,840 Speaker 3: another one might be delays that are faced. Maybe you're 353 00:19:23,880 --> 00:19:27,040 Speaker 3: not necessarily keeping up with a surge in demand over 354 00:19:27,200 --> 00:19:30,760 Speaker 3: say respiratory season, which we're now entering. If a lot 355 00:19:30,800 --> 00:19:33,280 Speaker 3: more people are seeking a certain drug and there's only 356 00:19:33,280 --> 00:19:35,400 Speaker 3: so many manufacturers, they might not be able to keep 357 00:19:35,480 --> 00:19:38,040 Speaker 3: up with demand too. So lots of different reasons for 358 00:19:38,200 --> 00:19:40,359 Speaker 3: drug shortages in the US. And I want to be 359 00:19:40,480 --> 00:19:44,040 Speaker 3: clear even as we discuss some of the challenges that 360 00:19:44,119 --> 00:19:47,840 Speaker 3: FDA has an oversight of the pharmaceutical supply chain that 361 00:19:47,920 --> 00:19:50,800 Speaker 3: exists abroad. That's not to say there aren't those quality 362 00:19:50,840 --> 00:19:53,840 Speaker 3: issues here in the United States as well. So it 363 00:19:54,040 --> 00:19:57,640 Speaker 3: exists in both places. And one of the underlying problems 364 00:19:57,680 --> 00:20:00,560 Speaker 3: is a lot of these companies don't have the money 365 00:20:00,560 --> 00:20:05,480 Speaker 3: to invest in advanced manufacturing, in automating systems. They leave 366 00:20:05,560 --> 00:20:08,800 Speaker 3: room for human error and to upgrade the facilities so 367 00:20:08,840 --> 00:20:11,720 Speaker 3: that it runs like a tight ship. Like over at 368 00:20:11,760 --> 00:20:15,040 Speaker 3: Pfizer where they make the vaccine, they don't have Pfizer's money, 369 00:20:15,119 --> 00:20:19,239 Speaker 3: they can't make those same investments. Pfizer has invested so 370 00:20:19,400 --> 00:20:23,080 Speaker 3: much money in production of the COVID vaccine with many 371 00:20:23,119 --> 00:20:26,000 Speaker 3: facilities here in the United States. That is a product 372 00:20:26,080 --> 00:20:28,840 Speaker 3: that has made tens of billions of dollars on an 373 00:20:28,880 --> 00:20:33,000 Speaker 3: annual basis. The COVID vaccine and its COVID therapeutic doubled 374 00:20:33,160 --> 00:20:35,680 Speaker 3: its revenue in a single year, so they can feed 375 00:20:35,720 --> 00:20:38,840 Speaker 3: that money back into the process. With generic drugs that 376 00:20:39,240 --> 00:20:41,959 Speaker 3: only cost cents on the dollar or a few dollars 377 00:20:41,960 --> 00:20:45,360 Speaker 3: at that, you don't have the same capital to reinvest 378 00:20:45,359 --> 00:20:48,439 Speaker 3: in the manufacturing process, and a lot of companies end 379 00:20:48,520 --> 00:20:49,320 Speaker 3: up cutting corners. 380 00:20:52,800 --> 00:20:55,560 Speaker 1: Are there safety risks to having so many of the 381 00:20:55,640 --> 00:20:59,240 Speaker 1: drugs that we take manufactured overseas where say the FDA 382 00:20:59,359 --> 00:21:02,080 Speaker 1: doesn't have as much oversight into them, or is that 383 00:21:02,240 --> 00:21:03,240 Speaker 1: not really a problem? 384 00:21:03,840 --> 00:21:07,080 Speaker 3: It is increasingly a problem, and it's one that we 385 00:21:07,119 --> 00:21:09,600 Speaker 3: at Bloomberg have taken a lot of time to examine 386 00:21:09,600 --> 00:21:12,960 Speaker 3: this year. There is evidence of generic drug makers abroad 387 00:21:12,960 --> 00:21:15,760 Speaker 3: cutting corners to keep costs down and evade being caught 388 00:21:15,880 --> 00:21:18,879 Speaker 3: for quality issues. So this year alone, our colleagues have 389 00:21:18,920 --> 00:21:23,040 Speaker 3: written about contaminated eye drops, poisoned coft syuroup which is 390 00:21:23,480 --> 00:21:25,919 Speaker 3: over the counter, and low quality abortion pills. I mean, 391 00:21:25,960 --> 00:21:28,360 Speaker 3: there are a number of cases the FDA would say, 392 00:21:28,359 --> 00:21:32,760 Speaker 3: trust your generic drugs. But Congress is certainly looking at 393 00:21:32,760 --> 00:21:37,040 Speaker 3: this question and pushing for more inspections abroad and other 394 00:21:37,240 --> 00:21:42,560 Speaker 3: forms of oversight and investment that will ensure quality moving forward. 395 00:21:43,760 --> 00:21:46,960 Speaker 1: When we come back, will the Biden administration give a 396 00:21:47,119 --> 00:21:58,000 Speaker 1: boost to generic drug makers? So if there is an 397 00:21:58,040 --> 00:22:03,000 Speaker 1: advantage both from a production standandpoint and for quality control 398 00:22:03,119 --> 00:22:06,920 Speaker 1: to have these medicines made in the US, but US 399 00:22:07,000 --> 00:22:10,160 Speaker 1: manufacturers can't afford to make a lot of them, what's 400 00:22:10,200 --> 00:22:13,119 Speaker 1: the solution here? How do we actually solve this problem? 401 00:22:13,600 --> 00:22:16,679 Speaker 3: I wish I had the conclusive answer to that question. 402 00:22:16,800 --> 00:22:19,280 Speaker 3: A lot of different stakeholders are now coming to the table, 403 00:22:19,960 --> 00:22:23,320 Speaker 3: particularly because of these acute drug shortages that have affected 404 00:22:23,640 --> 00:22:29,000 Speaker 3: life saving medicines like chemotherapies or basic antibiotics, to present 405 00:22:29,040 --> 00:22:32,960 Speaker 3: a solution. Many Congress people are pulling together legislation right 406 00:22:33,000 --> 00:22:36,080 Speaker 3: now to bolster US domestic drug production, and some of 407 00:22:36,080 --> 00:22:40,600 Speaker 3: the ideas include US health programs awarding contracts to US 408 00:22:40,640 --> 00:22:43,679 Speaker 3: based companies. That's one idea floating out there, calls to 409 00:22:43,720 --> 00:22:47,200 Speaker 3: actually increase prices of generic drugs. It's funny to say 410 00:22:47,240 --> 00:22:49,960 Speaker 3: that aloud, given so much of the discussion is about 411 00:22:50,440 --> 00:22:53,840 Speaker 3: lowering the cost of brand name pharmaceuticals, but again, this 412 00:22:53,880 --> 00:22:58,919 Speaker 3: is a totally different beast. Another is improving transparency in 413 00:22:58,920 --> 00:23:03,240 Speaker 3: the supply chain, simply having better data as to where 414 00:23:03,240 --> 00:23:07,040 Speaker 3: the supply is coming from up and downstream. We don't 415 00:23:07,080 --> 00:23:09,320 Speaker 3: want to just know where the generic is produced, we 416 00:23:09,359 --> 00:23:12,880 Speaker 3: want to know where the active pharmaceutical ingredients that underlie 417 00:23:12,920 --> 00:23:16,720 Speaker 3: that generic are made, and even the raw materials beneath that. 418 00:23:17,119 --> 00:23:20,359 Speaker 3: Having more visibility into the supply chain and a sense 419 00:23:20,400 --> 00:23:23,960 Speaker 3: of how many manufacturers exist, where they are, what kind 420 00:23:24,000 --> 00:23:27,280 Speaker 3: of quality issues they may have had in the past, 421 00:23:27,600 --> 00:23:30,040 Speaker 3: goes a long way to ensuring the security of the 422 00:23:30,080 --> 00:23:35,080 Speaker 3: supply chain. Another would be then taking those manufacturers and 423 00:23:35,200 --> 00:23:38,640 Speaker 3: ensuring they are properly registered with the FDA, And then 424 00:23:38,680 --> 00:23:42,400 Speaker 3: of course talk of grants, tax incentives, and loans. 425 00:23:43,280 --> 00:23:45,760 Speaker 1: We've also seen from the Biden administration a lot of 426 00:23:45,800 --> 00:23:48,480 Speaker 1: money to try to bring them manufacturing back to the US. 427 00:23:48,880 --> 00:23:52,440 Speaker 1: Is there any thought of putting that kind of incentives 428 00:23:52,520 --> 00:23:54,120 Speaker 1: into generic drugs as well. 429 00:23:54,840 --> 00:23:57,720 Speaker 3: Earlier this year we reported on a secret White House 430 00:23:57,800 --> 00:24:01,760 Speaker 3: effort to tackle this very qui question of how to 431 00:24:02,119 --> 00:24:05,800 Speaker 3: resolve drug shortages and underline quality issues that are driving them. 432 00:24:06,440 --> 00:24:08,800 Speaker 3: The team was formed by two White House bodies, the 433 00:24:08,880 --> 00:24:12,600 Speaker 3: National Economic Council and the Domestic Policy Council, with support 434 00:24:12,680 --> 00:24:15,200 Speaker 3: from other parts of the White House, and they were 435 00:24:15,200 --> 00:24:18,679 Speaker 3: really looking at this as a economic question, how do 436 00:24:18,760 --> 00:24:21,680 Speaker 3: we support industry. Some of the things that they were 437 00:24:21,680 --> 00:24:26,960 Speaker 3: thinking about were these tax incentives grants. Another novel concept 438 00:24:27,040 --> 00:24:30,840 Speaker 3: was doing third party quality assessment, saying, hey, are there 439 00:24:30,880 --> 00:24:34,040 Speaker 3: outsiders that we can bring to the table that can 440 00:24:34,080 --> 00:24:37,800 Speaker 3: examine the pharmaceutical supply chain and say we see a 441 00:24:37,800 --> 00:24:40,480 Speaker 3: problem here. But it remains to be seen whether or 442 00:24:40,560 --> 00:24:44,320 Speaker 3: not they will achieve something at the scale of say chips, 443 00:24:44,720 --> 00:24:48,920 Speaker 3: the Chips Act, which was about bringing chips production back 444 00:24:48,960 --> 00:24:51,679 Speaker 3: here to the United States, among many other things. But 445 00:24:52,200 --> 00:24:55,919 Speaker 3: we have not seen a Chips for pharma, despite people 446 00:24:55,920 --> 00:24:58,520 Speaker 3: advocating for it, and despite folks at the White House 447 00:24:58,600 --> 00:25:03,200 Speaker 3: really thinking critically about all the different ways to approach 448 00:25:03,359 --> 00:25:04,119 Speaker 3: this problem. 449 00:25:04,720 --> 00:25:06,800 Speaker 1: So we have a secret task urse inside the White House. 450 00:25:06,800 --> 00:25:08,280 Speaker 1: Why does it have to be secret? 451 00:25:08,640 --> 00:25:09,800 Speaker 3: That's a good question, Wes. 452 00:25:11,240 --> 00:25:13,280 Speaker 4: No answer there, No answer. 453 00:25:12,960 --> 00:25:16,840 Speaker 1: There, sirre Lely, I got to ask you. You must be 454 00:25:16,840 --> 00:25:19,000 Speaker 1: a whole lot of fun to watch TV with when 455 00:25:19,200 --> 00:25:20,560 Speaker 1: a pharmaceutical ad comes on. 456 00:25:21,119 --> 00:25:22,359 Speaker 4: Oh yeah, oh yeah. 457 00:25:22,400 --> 00:25:25,919 Speaker 3: I mean many of those drugs I knew like the 458 00:25:25,960 --> 00:25:28,760 Speaker 3: back of my hand for a while, because that's what 459 00:25:29,000 --> 00:25:32,080 Speaker 3: my beat was at Bloomberg was reporting on the blockbusters, 460 00:25:32,119 --> 00:25:34,600 Speaker 3: the new to market drugs that were trying to reap 461 00:25:34,640 --> 00:25:37,000 Speaker 3: as much as they could in sales in that specific 462 00:25:37,040 --> 00:25:40,960 Speaker 3: window before patent expires. You will never see it and 463 00:25:41,359 --> 00:25:44,439 Speaker 3: add on television for a generic drug. It's just not 464 00:25:44,560 --> 00:25:47,080 Speaker 3: how it works. So if you're seeing something on TV 465 00:25:47,560 --> 00:25:50,240 Speaker 3: that is a brand name product that has got a 466 00:25:50,280 --> 00:25:53,560 Speaker 3: totally different business model than the generics that might be 467 00:25:53,600 --> 00:25:55,360 Speaker 3: in your medicine cabinet. 468 00:25:55,400 --> 00:25:57,920 Speaker 1: Riley always great talking with you. Thanks for taking the time, 469 00:25:58,119 --> 00:26:01,320 Speaker 1: Thanks Wes, Thanks for listening to us here at the 470 00:26:01,320 --> 00:26:04,520 Speaker 1: Big Take. It's a daily podcast from Bloomberg and iHeartRadio. 471 00:26:04,840 --> 00:26:08,919 Speaker 1: For more shows from iHeartRadio, visit the iHeartRadio app, Apple Podcasts, 472 00:26:08,960 --> 00:26:11,479 Speaker 1: or wherever you listen and we'd love to hear from you. 473 00:26:11,720 --> 00:26:14,760 Speaker 1: Email us questions or comments to Big Take at Bloomberg 474 00:26:14,800 --> 00:26:17,879 Speaker 1: dot net. The supervising producer of The Big Take is 475 00:26:18,000 --> 00:26:22,280 Speaker 1: Vicky Bergolino. Our senior producer is Katherine Fink. This episode 476 00:26:22,320 --> 00:26:26,440 Speaker 1: was produced by Sam Gebauer and Christine Driscoll. Hilde Garcia 477 00:26:26,560 --> 00:26:30,240 Speaker 1: is our engineer. Our original music was composed by Leo Sidrin. 478 00:26:30,600 --> 00:26:33,720 Speaker 1: I'm West Kasova. We'll be back tomorrow with another Big 479 00:26:33,760 --> 00:26:34,000 Speaker 1: Take