WEBVTT - How Hypoallergenic Cats Work

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<v Speaker 1>Brought to you by the reinvented two thousand twelve camera.

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<v Speaker 1>It's ready. Are you welcome to stuff you should know

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<v Speaker 1>from House Stuff Works dot Com? Meaw, and welcome to

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<v Speaker 1>the podcast. I'm Josh Clark. That's Chuck Bryant. I was

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<v Speaker 1>the same thing. That's yeah, I was cat. That was terrible.

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<v Speaker 1>It was a pretty bad. That's about as good as

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<v Speaker 1>your elvis impression. Um, actually, Chuck, it was great. Um,

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<v Speaker 1>I'm sorry. I just can't so, Chuck, you have cat.

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<v Speaker 1>I have two cats. I have Laurn and I have

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<v Speaker 1>the Wizard. Nice two cats. You hate it when people

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<v Speaker 1>name their pets like actual human names, like Jason or

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<v Speaker 1>you know, Gina. You know my in laws are big

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<v Speaker 1>on that. They always give their dogs regular names. Well,

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<v Speaker 1>my apologies to your in laws. Chick, well Laurn, it

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<v Speaker 1>gets conceivably your real name, but the Wizard the Wizard. Yet,

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<v Speaker 1>you're you're probably going to be brought up on charges

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<v Speaker 1>if you name your kid the Wizard. Okay, So, so

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<v Speaker 1>you know what it's like to live among tumble weeds

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<v Speaker 1>of of hair just kind of going through your house.

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<v Speaker 1>You know, the mice put on little um gunslinging shows

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<v Speaker 1>too for your amusement kind of thing. Right, Between our

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<v Speaker 1>two cats and two dogs, we could literally collect enough

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<v Speaker 1>hair each week to make an entirely new animal. Yeah. Yeah,

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<v Speaker 1>I could sweep every day and still get an astronomical amount. Up,

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<v Speaker 1>I'm too lazy, though, I don't sweep every day. So

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<v Speaker 1>we live in a toxic environment. My wife, Emily is

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<v Speaker 1>is she Yeah, but she loves animals so much that

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<v Speaker 1>she lives with it. And so your wife, Emily, you realize,

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<v Speaker 1>is part of the one third of Americans who love

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<v Speaker 1>cats so much that they keep them even though they're

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<v Speaker 1>allergic to them. Yeah, think about that. A third of

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<v Speaker 1>the people who are allergic to cats still keep That

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<v Speaker 1>says something about cats. It really does, doesn't it. Yeah

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<v Speaker 1>that's pretty cool. Yeah, it's awesome. So what does Emily

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<v Speaker 1>do for allergies? Well, she's got big allergies as a

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<v Speaker 1>hole anyway, So she's on shots and pills and nasal sprays.

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<v Speaker 1>And there's a voodoo guy that comes around once a

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<v Speaker 1>week and does a little nude dance in our room,

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<v Speaker 1>and that has nothing to do with the allergy. Nothing.

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<v Speaker 1>She did you dye your hair read recently? No, she

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<v Speaker 1>has not, So she's on a slew of things, but

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<v Speaker 1>it still acts up. You know, those are some bad

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<v Speaker 1>allergy You got bad allergies? Wow, How how often does

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<v Speaker 1>it act up? Uh, it's the allergy shots have kind

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<v Speaker 1>of worked, so it's not as often, but you know,

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<v Speaker 1>during the worst of times, it was, you know, a

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<v Speaker 1>couple of times a week severe debilitating allergy as well. Yeah. Well,

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<v Speaker 1>and is it because of the cat. I'm sure that

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<v Speaker 1>doesn't help. Yeah, you know, I think her allergiest said

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<v Speaker 1>you should get rid of your animals, and she kind

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<v Speaker 1>of said, thanks, I'll get a new allergist. Well, okay,

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<v Speaker 1>So so she's a third of the population. People who

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<v Speaker 1>are allergic to cats still keep them, and about fifteen

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<v Speaker 1>the thirty percent of the population of the United States

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<v Speaker 1>has a ager cat allergy. Yeah, that's actually a lot

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<v Speaker 1>more people than I thought. It was pretty substantial, and

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<v Speaker 1>you know a lot of them will actually undergo uh

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<v Speaker 1>immunotherapy to kind of get over their allergy to it.

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<v Speaker 1>And it's just the shots. It is it's it's the shots.

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<v Speaker 1>It's um. It's basically it's like using local honey to

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<v Speaker 1>get over hay fever. Same concept, um, And the local

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<v Speaker 1>honey thing hasn't been proven, but it seems to work.

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<v Speaker 1>This actually has been proven. And all it is is

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<v Speaker 1>you're introducing a low level of the UM, the allergen

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<v Speaker 1>that's causing the allergic reaction UM, and letting your body

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<v Speaker 1>get used to it. Correct. You want to talk about

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<v Speaker 1>allergic reactions for a second. That's my favorite topic, is it? Really?

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<v Speaker 1>I just have to deal with it a lot, so

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<v Speaker 1>I'm used to it. Okay, do you want to explain him? Uh?

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<v Speaker 1>I feel better if you did. Okay. So basically, UM,

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<v Speaker 1>an allergic reaction is nothing more than a case of

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<v Speaker 1>mistaken identity. Okay. So the cat allergy, the allergy in

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<v Speaker 1>that you're you're allergic to from the cat. Will get

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<v Speaker 1>to that in a second. UM, It's actually totally benign.

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<v Speaker 1>What happens is if the first time your body is

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<v Speaker 1>introduced to it and it takes it as a foreign invader, UM,

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<v Speaker 1>it will produce and uh animbody to fight it off,

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<v Speaker 1>and then every time it comes at it, it will

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<v Speaker 1>produce that anibody again. And basically one of the results

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<v Speaker 1>is the release of histamines, which actually UM makes your

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<v Speaker 1>It opens up the capillaries and your soft tissue, which

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<v Speaker 1>is why your eyes water and your sneeze and your

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<v Speaker 1>gums bleed and you get the spins. Yeah, well that's

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<v Speaker 1>another one too. Yeah. So so that's actually the reason

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<v Speaker 1>why that's amazing, he really think. So, yeah, how the

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<v Speaker 1>human body works. I love that stuff. I think it's

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<v Speaker 1>strange that the human body can make a mistake like that,

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<v Speaker 1>you know, stupid body. Yeah. So, so what is this

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<v Speaker 1>cat allergen? I believe it's called UM. I'm not sure

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<v Speaker 1>if you say it or spell it, and I'm gonna

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<v Speaker 1>spell it f E L D one glycoprotein and f

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<v Speaker 1>L clearly stands for a feline. So no matter how

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<v Speaker 1>you say it, what it is is UM. It's something

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<v Speaker 1>that cats secrete through their skin and their saliva. And

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<v Speaker 1>it's actually smaller than dust. Yeah, and it gets everywhere,

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<v Speaker 1>doesn't it does. There was actually a study of UM

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<v Speaker 1>a mattress store in Sweden. This was disturbing. It was disturbing. Um,

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<v Speaker 1>they're all these mattresses for sale. You know how they

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<v Speaker 1>have mattresses out box spring sets and you can lay

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<v Speaker 1>on them. They actually, Um, you have never been one

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<v Speaker 1>to actually get on the mattress, but you know, people

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<v Speaker 1>rolling around and stuff. I don't like that at all.

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<v Speaker 1>So these are brand new mattresses that have never been

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<v Speaker 1>in anyone's home, and they the Swedes tested them for

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<v Speaker 1>the felled one GLCO or the fel D one glycoprotein

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<v Speaker 1>UH and found it in aces on every single one

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<v Speaker 1>of them. So this just came from people that the cats.

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<v Speaker 1>So it's very easily transferred, very small. Um, it's almost

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<v Speaker 1>impossible to get rid of UH. And your cat produces

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<v Speaker 1>it constantly through saliva. A glycoprotein. Actually it's it's it

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<v Speaker 1>does all sorts of different stuff. It's found everywhere. Um,

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<v Speaker 1>it conserves a lubricant. Uh, it can serve as a

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<v Speaker 1>connective tissue, right. Uh. It's also structural, so it can

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<v Speaker 1>be found in cell walls. It's all over the place,

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<v Speaker 1>and it's big and keratin, which is the hair partly, right,

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<v Speaker 1>which is why pet dander is so allergic. You got it? Okay, man,

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<v Speaker 1>you're smarter than I thought. How Thanks, It's good stuff.

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<v Speaker 1>So okay, that's the glycoprotein, right, that's the histamine reaction.

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<v Speaker 1>That is the you know cat thing. We've already discussed

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<v Speaker 1>all of our and a lot of people are allergic

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<v Speaker 1>to UH. Two cats. I think the stat is umi

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<v Speaker 1>of asthma cases are allergy related, and of those are

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<v Speaker 1>cat allergies. Yeah, okay, yeah, cats in particular tune to

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<v Speaker 1>be very allergic. So what do you do, I mean,

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<v Speaker 1>asides you know Emily's course of action. Sure, I know

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<v Speaker 1>one thing that the article mentions is washing your cat

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<v Speaker 1>twice a week. But if your cat, my cat, cats

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<v Speaker 1>don't like that. No. I washed my kitten, Lauren when

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<v Speaker 1>I found him in a dumpster in Los Angeles. And

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<v Speaker 1>I washed him when I first got him immediately because

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<v Speaker 1>he was a dumpster kittie. And uh, I tried to

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<v Speaker 1>wash him again about and he's I don't probably five

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<v Speaker 1>years old now. I tried to wash him again give

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<v Speaker 1>him a fleet path about six months ago, and he

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<v Speaker 1>was not happy. Now now, he he just complained a lot.

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<v Speaker 1>He didn't he didn't like fight us or anything. But yeah,

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<v Speaker 1>there are some cats out there that will draw blood

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<v Speaker 1>if you try to put water on them. My other cat,

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<v Speaker 1>the Wizard, would he would attack. Yeah, so you know

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<v Speaker 1>better than to wash him. So that's not necessarily an

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<v Speaker 1>appropriate course of action either. No, depending on your cat.

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<v Speaker 1>Do you know what is please tell me you could

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<v Speaker 1>buy what is called a hypo allergenic cat. Yes, if

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<v Speaker 1>you have a cool six thousand dollars to spare six grand,

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<v Speaker 1>it's actually what probably so six grand. There's a company

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<v Speaker 1>called Allerca, uh, and it's an American company, I believe.

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<v Speaker 1>And basically they have created a cat that they market

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<v Speaker 1>as a hypoallergenic cat. And they don't have to prove

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<v Speaker 1>that one bit. According to the FDA anything, any product

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<v Speaker 1>in the US marketed as hypoallergenic doesn't have to produce

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<v Speaker 1>any proof whatsoever that it's hypo allergenic. And hypoallergenic doesn't

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<v Speaker 1>mean allergy free. It just means that there's a much

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<v Speaker 1>less likelihood, um that you that it will produce an

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<v Speaker 1>allergic reaction. But to back up its claims, Allerca published

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<v Speaker 1>its own study UH. And basically the study could be

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<v Speaker 1>called here smell these cats. So they took some people

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<v Speaker 1>who who are known to have cat allergies and control

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<v Speaker 1>group uh that that doesn't have cat allergies, and um,

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<v Speaker 1>they used the the Allerca Allerca cats and basically said,

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<v Speaker 1>here you go, you know, here's this cat, and neither

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<v Speaker 1>group react to the cat. It seems to work. But

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<v Speaker 1>then they used a non out regular cat and yeah

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<v Speaker 1>there was a reaction, right, it's kind of meat, but

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<v Speaker 1>it is really serves to help market their cause. Well,

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<v Speaker 1>the first thing I thought when I saw this article

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<v Speaker 1>about hypologenic cats is that it was some sort of

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<v Speaker 1>weird bioengineered type of thing, like a a mouse within

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<v Speaker 1>ear growing out it's back, right, which we have a

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<v Speaker 1>picture of. It's really weird looking disturbing. We paid extra

0:09:27.200 --> 0:09:32.280
<v Speaker 1>for that one. It's an ap photo. It's worth every penny. Um. So, yeah,

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<v Speaker 1>it's not actually bioengineering though, So those that that I

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<v Speaker 1>don't agree with things like that, don't worry. It's actually

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<v Speaker 1>selective breeding, yes, And selective breeding basically is you're just

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<v Speaker 1>taking um, you know, a group that has a desirable

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<v Speaker 1>trait and and continuing to breed them while not letting

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<v Speaker 1>them breed with the the cats that have the trait

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<v Speaker 1>you don't want. And in this case, um Alerca used

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<v Speaker 1>a process called bioinformatic, which is basically slapping computers and

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<v Speaker 1>molecular biology together. And from what I gather, they fed

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<v Speaker 1>the genetic makeup of I guess, several different breeds of

0:10:09.920 --> 0:10:14.320
<v Speaker 1>cats into through an algorithm and it basically spit out

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<v Speaker 1>likelihoods that that these breeds would stop producing the fel

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<v Speaker 1>D one glycoprotein based on their genetic makeup. Right, it's

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<v Speaker 1>no wonder. It cost six grand yeah yeah, right, so

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<v Speaker 1>they and I imagine selective breeding keeping these cats from

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<v Speaker 1>mating constantly. It's probably a real pain. It's a job. Um.

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<v Speaker 1>So they what what the computer basically said was go

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<v Speaker 1>check out the British short hair, and so they grabbed

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<v Speaker 1>the British short hair, which I guess had the highest

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<v Speaker 1>likelihood of abandoning this gene that produces it. Right, Well,

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<v Speaker 1>actually it doesn't. It still has the the f l

0:10:50.600 --> 0:10:53.600
<v Speaker 1>D one protein, but it's just a different version of it, right, Okay, yeah,

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<v Speaker 1>it has a different molecular way exactly, absolutely okay. Um,

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<v Speaker 1>So they basically bread it, bread it out of them.

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<v Speaker 1>They bread the the f LD one f e l

0:11:03.200 --> 0:11:05.880
<v Speaker 1>D one. We're gonna breathe that Glaco protein right out

0:11:05.880 --> 0:11:08.559
<v Speaker 1>of you right now. Yeah. And and what what happened

0:11:08.679 --> 0:11:12.520
<v Speaker 1>was these the Alerca cats. Now they may look exactly

0:11:12.559 --> 0:11:15.520
<v Speaker 1>like a British short hair cat, but it's technically another species.

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<v Speaker 1>A species a speciation event actually just occurred thanks to Alerca. Right,

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<v Speaker 1>So it's genetic divergence. It's where you take one thing

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<v Speaker 1>and put them in there, split them in the two

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<v Speaker 1>on the tree of life. So yeah, oh yeah, they

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<v Speaker 1>there's a two year waiting list last I heard, and

0:11:34.720 --> 0:11:37.319
<v Speaker 1>you could cut the waiting time in half so you

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<v Speaker 1>could get it in a year, but you had to

0:11:39.280 --> 0:11:41.960
<v Speaker 1>pay an extra two grand, so an eight thousand dollar

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<v Speaker 1>cat and you had to wait a year for it. Right,

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<v Speaker 1>So I guess they are pretty popular. Either that or

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<v Speaker 1>they're breeding fairly slowly. Right, These are some serious cat

0:11:49.880 --> 0:11:52.559
<v Speaker 1>lovers out there, there are. But then again, I mean

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<v Speaker 1>your wife, she puts up with these allergies and she

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<v Speaker 1>would draw the line there though. Yeah. Well, I guess

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<v Speaker 1>the moral for today is cat's equal. Great And if

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<v Speaker 1>you want to learn more about hype w allergenet cats,

0:12:05.640 --> 0:12:07.720
<v Speaker 1>you can type that into our Handy Danny search bar

0:12:08.040 --> 0:12:11.240
<v Speaker 1>at how stuff works dot com. Also type in handy

0:12:11.280 --> 0:12:13.800
<v Speaker 1>Danny and see what comes up. You'll be pleasantly surprised.

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<v Speaker 1>But don't go anywhere. We have something we like to

0:12:17.520 --> 0:12:23.120
<v Speaker 1>call the listener mail. Yes, Josh, we're back, as I say,

0:12:23.320 --> 0:12:26.640
<v Speaker 1>mere seconds later, and uh, I'm just gonna entitle this

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<v Speaker 1>segment from our young fans. We get some emails from

0:12:29.760 --> 0:12:32.000
<v Speaker 1>some of our young fans. We love our young fans.

0:12:32.000 --> 0:12:33.920
<v Speaker 1>We love the kids out there listening to us when

0:12:33.920 --> 0:12:36.319
<v Speaker 1>they listen to the you know, age appropriate shows. Were

0:12:36.360 --> 0:12:38.000
<v Speaker 1>we going to stick that at the end of Moonshine

0:12:38.000 --> 0:12:39.920
<v Speaker 1>and then thought the better of it? We did, Actually,

0:12:41.080 --> 0:12:43.240
<v Speaker 1>now we're putting it after the hype wallergenet cat went

0:12:43.440 --> 0:12:46.600
<v Speaker 1>much much more appropriate exactly. So, um we heard from

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<v Speaker 1>Cole Silva and Marston Mills, Massachusetts about flirting and young

0:12:51.520 --> 0:12:53.320
<v Speaker 1>Cole is twelve years old and he says that he

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<v Speaker 1>loved the episode on flirting and it really helped him

0:12:55.720 --> 0:12:58.480
<v Speaker 1>a lot. And I may only be twelve, but thanks

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<v Speaker 1>to you, I just found out that a lot of

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<v Speaker 1>girls have flirted with me this year. So, as you know,

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<v Speaker 1>I wrote back to Cole and told him here's another

0:13:05.640 --> 0:13:08.280
<v Speaker 1>bit of advice. Be nice and respectful to your female

0:13:08.280 --> 0:13:10.400
<v Speaker 1>friends and that'll give you a leg up in the

0:13:10.440 --> 0:13:13.200
<v Speaker 1>future on all those little dorky friends that make fun

0:13:13.200 --> 0:13:19.920
<v Speaker 1>of them pigtails. Good advice from us. Uh. Then um Ben,

0:13:20.080 --> 0:13:23.560
<v Speaker 1>fifteen years old in England, one of our favorites. He

0:13:24.240 --> 0:13:29.559
<v Speaker 1>enjoyed the toothpaste making orange juice taste bad, and I

0:13:29.559 --> 0:13:32.080
<v Speaker 1>wrote Ben back as I am uh want to do

0:13:32.280 --> 0:13:35.360
<v Speaker 1>and he to ask for a high kup poem from

0:13:35.360 --> 0:13:38.600
<v Speaker 1>Ben from love as for hik I do. It's short

0:13:38.640 --> 0:13:40.240
<v Speaker 1>and it's a good way to get them involved and

0:13:40.320 --> 0:13:44.119
<v Speaker 1>engage our listeners. So he wrote back in January, snowfalls

0:13:44.120 --> 0:13:47.600
<v Speaker 1>on the frozen ground. I make a snowman. That sounds

0:13:47.640 --> 0:13:49.040
<v Speaker 1>like a T shirt to me. It's a good one.

0:13:49.520 --> 0:13:52.320
<v Speaker 1>And then Sarah s this is our favorite. Sarah S

0:13:52.320 --> 0:13:55.080
<v Speaker 1>a k a. The amazing eleven year old fan is

0:13:55.080 --> 0:13:58.360
<v Speaker 1>writing us on a weekly basis, if not daily now,

0:13:58.720 --> 0:14:02.080
<v Speaker 1>and Sarah is very awesome. She's eleven, and she wrote

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<v Speaker 1>out a haiku for us which actually rhymes and Sarah,

0:14:05.080 --> 0:14:06.840
<v Speaker 1>you should know that they don't have to rhyme. In fact,

0:14:06.960 --> 0:14:09.040
<v Speaker 1>him know she put in the extra effort, but she

0:14:09.080 --> 0:14:11.240
<v Speaker 1>did from knowing Sarah, she she knew that she just

0:14:11.280 --> 0:14:13.560
<v Speaker 1>wanted to follows it up even more right. So here's

0:14:13.559 --> 0:14:18.040
<v Speaker 1>sarah S's haikul. Many people run straight into the sun

0:14:18.120 --> 0:14:21.200
<v Speaker 1>for fun, but I am not one. And she says

0:14:21.240 --> 0:14:24.360
<v Speaker 1>she wrote that because she hates to run nice and

0:14:24.560 --> 0:14:26.800
<v Speaker 1>apparently isn't much of a fan of the Sun music. Right,

0:14:26.880 --> 0:14:28.760
<v Speaker 1>but we we love our young fans and we appreciate

0:14:28.800 --> 0:14:32.080
<v Speaker 1>them listening. Do we have any youth size your T shirts?

0:14:32.480 --> 0:14:35.040
<v Speaker 1>I don't think so. They could be sleep shirts. Okay,

0:14:35.080 --> 0:14:37.400
<v Speaker 1>there you go. So if you guys ever go to

0:14:37.440 --> 0:14:40.200
<v Speaker 1>a sleepover, you can be sporting your cool how Stuff

0:14:40.200 --> 0:14:44.000
<v Speaker 1>Works T shirt. Just that emails your addresses the three

0:14:44.000 --> 0:14:46.040
<v Speaker 1>of you. Thank you very much for writing in, and

0:14:46.080 --> 0:14:48.240
<v Speaker 1>if you want to write in and roll the dice

0:14:48.280 --> 0:14:49.720
<v Speaker 1>to see if you can get a T shirt, or

0:14:50.080 --> 0:14:52.160
<v Speaker 1>just tell Chuck and I that we made a mistake

0:14:52.280 --> 0:14:54.760
<v Speaker 1>or that you love us, whatever, just send an email

0:14:54.800 --> 0:15:00.400
<v Speaker 1>to Stuff Podcast at how stuff works dot com m HM.

0:15:02.480 --> 0:15:05.040
<v Speaker 1>For more on this in thousands of other topics, visit

0:15:05.080 --> 0:15:09.720
<v Speaker 1>how stuff Works dot com MHM. Brought to you by

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<v Speaker 1>the reinvented two thousand twelve camera. It's ready, are you