WEBVTT - Anatomy of a Hangover 0:00:03.800 --> 0:00:06.680 Welcome to Stuff to Blow your Mind from how Stuff 0:00:06.680 --> 0:00:13.760 Works dot com. Hey, welcome to stuff to Blow your Mind. 0:00:13.800 --> 0:00:16.520 My name is Robert Lamb and I'm Julie Douglas. Julie 0:00:16.520 --> 0:00:24.240 wins last for me to hangover? Um definitely not this morning. Um. 0:00:24.560 --> 0:00:27.400 In the last six months plus six months, yeah, yeah, 0:00:27.680 --> 0:00:32.080 I had one personal long time actually last weekend. Yeah, 0:00:32.600 --> 0:00:35.440 Sunday morning, which is not my usual thing. I can't 0:00:35.440 --> 0:00:37.199 remember the last time I actually had one, because I'm 0:00:37.200 --> 0:00:40.479 generally not a big drinker, but you know, occasionally go 0:00:40.520 --> 0:00:43.760 to a party and somebody will have will provide the alcohol. 0:00:44.440 --> 0:00:47.279 And it's when they don't either either they're they're new 0:00:47.320 --> 0:00:49.440 to the idea of mixing up a large quantity of 0:00:49.440 --> 0:00:52.880 a drink and then forcing them upon people, or that 0:00:53.000 --> 0:00:56.400 or they don't understand basic chemistry or something. That's when 0:00:56.400 --> 0:00:59.320 I encountered the disastrous effects. In this case, it was 0:00:59.400 --> 0:01:02.720 an overly strong margharita that had been mixed up for everybody, 0:01:02.800 --> 0:01:04.920 because like a Mexican Christmas party, it was a great party. 0:01:04.959 --> 0:01:08.440 But but the margarita's were basically tequila and ice and 0:01:08.520 --> 0:01:12.160 some sugar and and that was a bad situation. In 0:01:12.560 --> 0:01:16.000 other cases, I've encountered. Um uh, you know, you go 0:01:16.040 --> 0:01:18.319 to a party and someone will hand out jello shots 0:01:19.080 --> 0:01:23.120 and they won't even solidify that they're they're so poorly mixed, 0:01:23.160 --> 0:01:25.840 and that is generally disastrous. Okay, well I have to 0:01:25.880 --> 0:01:29.800 say that the festive Mexican Christmas party, I feel kind 0:01:29.840 --> 0:01:33.760 of relieved. I thought you were doing keg stands or something. Yeah. Yeah, 0:01:34.160 --> 0:01:37.720 but we're definitely talking about this, uh today this podcast, 0:01:37.760 --> 0:01:41.479 because what's coming up New Year's right, Yeah, lots of revelry, 0:01:41.520 --> 0:01:44.440 lots of debauchery, and in fact, if your Norwegian, maybe 0:01:44.440 --> 0:01:49.240 you even say that it could lead to va Oh yes, 0:01:49.320 --> 0:01:52.800 this is one of the older terms for for the hangover. Yeah, yeah, 0:01:52.840 --> 0:01:56.880 I mean it actually means uneasiness following debauchery. Do you 0:01:56.880 --> 0:02:01.120 think the the hangover movies are called vessels? You over there? 0:02:01.160 --> 0:02:03.280 Because I feel like if I was told, Hey, we're 0:02:03.280 --> 0:02:05.120 gonna go see this movie but selgy it sounds like 0:02:05.160 --> 0:02:08.520 a really serious Norwegian you know, black and white art film, 0:02:08.560 --> 0:02:10.080 and I would be like, ah, let's see that, and 0:02:10.080 --> 0:02:12.400 then I would I would be rather disappointed. But then 0:02:12.440 --> 0:02:14.919 you'd feel like there's a monkey in there. Oh, such 0:02:15.280 --> 0:02:17.960 data ism, such surrealism. Well the monkey, y know, well 0:02:18.000 --> 0:02:20.160 it would be used in a more surreal fashion. I imagine, 0:02:20.240 --> 0:02:21.960 that's right. Yeah, but but yeah, and so in this 0:02:22.000 --> 0:02:24.880 podcast we are going to talk about the hangover, the 0:02:24.880 --> 0:02:27.880 the the actual hangover, what what's going on in it? Wait, 0:02:27.919 --> 0:02:30.200 you can do to prevent it to well, I mean 0:02:30.240 --> 0:02:31.919 the big thing you can do to prevent it, of course, 0:02:32.000 --> 0:02:34.520 is to do not drink, and and hopefully too, as 0:02:34.560 --> 0:02:39.600 we discussed the uh the wages of of drinking, you will, um, 0:02:39.639 --> 0:02:43.680 you know, we're definitely not encouraging you to do. In fact, 0:02:43.880 --> 0:02:46.200 if anything that should I mean just reading over it 0:02:46.360 --> 0:02:48.440 and research again, I'm like, man, and maybe I shouldn't, 0:02:48.919 --> 0:02:51.919 you know, I should just skip everything? Well right right, 0:02:51.960 --> 0:02:53.440 by the end of this podcast, you'll have a really 0:02:53.440 --> 0:02:57.280 good idea of why it's super creepy. Actually, this hangover 0:02:57.360 --> 0:02:59.440 process that happens to your body is basically like a 0:02:59.480 --> 0:03:01.760 big talk six spill that your body has to clean up. 0:03:02.080 --> 0:03:04.840 And then you'll also understand why you keep doing it. 0:03:05.520 --> 0:03:08.000 So we'll cover that. But first of all, let's talk 0:03:08.040 --> 0:03:11.800 about what this feels like. What's a hangover to you? Well, 0:03:11.960 --> 0:03:14.639 I mean, there's a whole list of of things that 0:03:14.760 --> 0:03:16.720 it feels like a whole list of symptoms, and it 0:03:16.760 --> 0:03:19.400 depends a lot of It depends on exactly how this 0:03:19.480 --> 0:03:22.600 chemical spill plays out inside your body. There are several 0:03:22.639 --> 0:03:25.480 different factors that contribute to it, but the symptoms generally 0:03:25.680 --> 0:03:29.600 fall out like this headache obviously, and granted that can 0:03:29.760 --> 0:03:32.360 range from a slight headache and oh, I had a 0:03:32.360 --> 0:03:34.440 little bit much too much to drink last night headache 0:03:34.440 --> 0:03:37.440 to a my skull is about to fall in half headache. Yes, 0:03:37.560 --> 0:03:40.080 poor sense of overall well being, you know the words. 0:03:40.120 --> 0:03:42.800 You just wake up and you just feel crappy, sensitivity 0:03:42.840 --> 0:03:45.800 to light and sound, so you wake up. Was I 0:03:45.840 --> 0:03:47.920 bid by a vampire? Or did I just drink a lot? 0:03:48.200 --> 0:03:53.920 You don't know. Diarrhea, loss of appetite, trembling, uh, not good, 0:03:54.040 --> 0:03:59.840 nausea of course, fatigue, increased heart rate and blood pressure, dehydration, 0:04:00.160 --> 0:04:02.960 dry mouth, extreme thirst, dry eyes. And this is really 0:04:03.040 --> 0:04:05.520 key and will discuss later on this dehydration because this 0:04:05.560 --> 0:04:08.360 has a lot to do with how you're feeling overall. Uh. 0:04:08.680 --> 0:04:13.400 Trouble concentrating, which is an interesting one because I was 0:04:13.440 --> 0:04:15.840 I was looking around, um and I couldn't find anything 0:04:15.880 --> 0:04:17.279 to back me up. In this. So this is one 0:04:17.320 --> 0:04:21.360 of those cases where I might have to say, hey, readers, listeners, rather, uh, 0:04:21.480 --> 0:04:23.080 if you have anything to add on this, I'd be 0:04:23.120 --> 0:04:25.599 interested to hear. I found what what are you gonna 0:04:25.680 --> 0:04:27.359 lay down on us? I found that in the in 0:04:27.400 --> 0:04:29.960 the in the rare cases that I have been hungover, 0:04:30.440 --> 0:04:32.479 there seems to be like a certain amount of hangover 0:04:32.560 --> 0:04:38.560 that is conducive to concentration on work like that. There's 0:04:38.560 --> 0:04:41.479 a certain amount. And I'm not saying it's necessarily the 0:04:41.600 --> 0:04:44.440 hangover made made me smarter or more concentrate. Maybe it's 0:04:44.440 --> 0:04:48.280 part of like you're overcompensating for the fact that you 0:04:48.279 --> 0:04:51.960 you potentially screwed up your current, your present by what 0:04:52.040 --> 0:04:54.599 you did in the past. So I don't know. I 0:04:54.640 --> 0:04:56.599 think that it would be interesting to hear from other people. 0:04:56.960 --> 0:04:59.920 Certainly could concentrate on TV watching, I'm sure a lot better. 0:05:00.360 --> 0:05:01.840 But if you're a parent like I am, and you 0:05:02.160 --> 0:05:04.560 if you do this foolish thing, you you have a 0:05:04.600 --> 0:05:07.840 hangover and you have a splitting headache. There's just yet 0:05:07.960 --> 0:05:10.839 concentrating is not going to happen. Uh. And then the 0:05:10.880 --> 0:05:15.240 other ones are anxiety difficulties, sleeping, and weakness. Yeah, I 0:05:15.279 --> 0:05:18.400 mean muscle weakness, right, Yeah, so of course it's just 0:05:18.520 --> 0:05:23.159 all these different factors of malaise that happens. And what 0:05:23.240 --> 0:05:26.120 can actually exacerbate this. To just keep in mind is 0:05:26.160 --> 0:05:28.640 that if you drink on an empty stomach, you could 0:05:28.640 --> 0:05:32.360 have a horrific hangover the next day if you have 0:05:32.440 --> 0:05:35.440 a lack of sleep. Um, let's say you dance for 0:05:35.560 --> 0:05:38.840 four hours straight. And the physical exertion is also a 0:05:38.839 --> 0:05:41.159 part of that too. Yeah, physical exertion and you lost 0:05:41.200 --> 0:05:44.719 a lot of the water content in your body right again, 0:05:44.760 --> 0:05:48.640 dehydration before drinking, and then poor health, which kind of 0:05:48.640 --> 0:05:50.560 makes sense, right, So if you've got the flu, it's 0:05:50.560 --> 0:05:53.400 probably not a good idea to go on a bender exactly. Yeah, 0:05:53.560 --> 0:05:57.000 don't compromise your body. Um. And I should also point 0:05:57.000 --> 0:05:59.280 out the whole like that you're weak, your muscles just 0:05:59.320 --> 0:06:01.839 don't have as much energy. I do remember one of 0:06:01.880 --> 0:06:05.560 the the times I was hungover in college. Um, I 0:06:05.600 --> 0:06:08.040 had to go into an acting class and they were 0:06:08.040 --> 0:06:09.840 doing a lot of body work that day, and it 0:06:09.960 --> 0:06:11.800 was there was a lot of like, we're gonna do 0:06:11.839 --> 0:06:14.560 some yoga stuff. And this was like a decade or 0:06:14.560 --> 0:06:17.080 so before I not a decade, but a long time 0:06:17.120 --> 0:06:19.560 before I actually got into yoga, So it was just 0:06:19.640 --> 0:06:22.080 pure torture, the idea, We're gonna do all these squats 0:06:22.160 --> 0:06:26.520 and and down dogs and uh and all this. Yeah, 0:06:26.520 --> 0:06:29.080 it's interesting you bring up the acting classes, because they do. 0:06:29.320 --> 0:06:34.279 They love all sorts of random body warming up experiments. 0:06:34.360 --> 0:06:36.960 I called them experiments because I have one teacher who 0:06:36.960 --> 0:06:39.839 loved Marcel Marceau and so we mined for like twenty 0:06:39.880 --> 0:06:42.719 minutes to get warmed up. I'm not kidding. And another 0:06:42.760 --> 0:06:46.159 teacher who liked to play an album that's like a 0:06:46.240 --> 0:06:51.320 charm and mow, um, it's supposed to be inspirational, uh 0:06:51.480 --> 0:06:54.679 this record, and that we would march information the liberal 0:06:54.720 --> 0:07:00.880 infiltration of academia. So yeah, and I'm just gonna throw 0:07:00.920 --> 0:07:03.599 this out there. Maybe hangover yoga is a thing. Maybe somebody. 0:07:03.800 --> 0:07:07.559 I'm sure that someone has created a hangover yoga for sure. Okay, 0:07:07.560 --> 0:07:10.640 So let's uh talk a little more about what happens, 0:07:10.760 --> 0:07:13.240 what happens in your body? And um, you touched on 0:07:13.320 --> 0:07:16.280 this earlier and you told us it was important that 0:07:16.360 --> 0:07:19.200 it is. It's this thing called the diuretic effect, right, 0:07:19.720 --> 0:07:22.960 alcohol sends your kidneys a message to send water directly 0:07:23.000 --> 0:07:25.480 to the bladder instead of reabsorbing it into the body. Okay, 0:07:25.520 --> 0:07:27.920 that's that's why when you have a beer, you know, 0:07:28.000 --> 0:07:29.600 twenty minutes later, you all of a sudden you have 0:07:29.640 --> 0:07:31.520 to go to the bathroom. Yeah, this is why. Well, yeah, 0:07:31.680 --> 0:07:35.440 it just becomes a NonStop trip back and forth to pee. Yeah. 0:07:35.440 --> 0:07:38.080 That's why the longer than night goes on, the harder 0:07:38.080 --> 0:07:40.280 it is to go use the bathroom at a bar 0:07:40.600 --> 0:07:42.800 in a reasonable amount of time, right, because everybody's cued up. 0:07:42.840 --> 0:07:44.840 And it's why the floor in the men's room at 0:07:44.840 --> 0:07:49.560 any given bar is like an inch deep in urine. Yeah, 0:07:49.600 --> 0:07:52.480 there you go. Another great reason to go and celebrating 0:07:52.520 --> 0:07:57.400 your local pub or bar. And this is called vasopressin inhibition. 0:07:57.920 --> 0:08:01.000 And this is a really interesting alcohol causes four times 0:08:01.040 --> 0:08:04.440 as much liquid to be lost as gained. Yeah, there 0:08:04.440 --> 0:08:06.280 are studies that showed the drinking about two d and 0:08:06.280 --> 0:08:09.680 fifty million liters of an alcoholic beverage caused the body 0:08:09.720 --> 0:08:13.240 to expel eight hundred to a thousand million liters of water. Yes, 0:08:13.320 --> 0:08:15.960 so there you go. Okay, so what's the big result 0:08:16.000 --> 0:08:17.720 of this is that you feel like a sun droid 0:08:17.760 --> 0:08:20.000 to me the next day, you are very dehydrated. That's 0:08:20.040 --> 0:08:22.320 the whole that's you know, your eyes feel dry, your 0:08:22.360 --> 0:08:26.400 mouth feels dry, so that kind of sound, you know. Yeah, 0:08:26.560 --> 0:08:28.760 and and of course your mouth feels like something died 0:08:28.800 --> 0:08:30.960 in it too. Yeah, there's there's some smells that we're 0:08:30.960 --> 0:08:32.880 not going to go into because we're gonna talk more 0:08:32.880 --> 0:08:36.199 about how your body actually feels. The creepiest part is 0:08:36.240 --> 0:08:38.320 that your organs are responsible for giving you a head 0:08:38.360 --> 0:08:43.760 splitting headache because they essentially steal water from your brain, 0:08:43.800 --> 0:08:46.240 causing it to decrease in size and pull on the 0:08:46.280 --> 0:08:50.199 membranes that connect the brain to the skull, causing the pain. Yeah, 0:08:50.400 --> 0:08:54.160 so they're they're like, look, there's a water shortage. Uh, 0:08:54.640 --> 0:08:57.640 us lower organs really need all the goods brain you're 0:08:57.679 --> 0:08:59.199 just gonna have to make do you got us into 0:08:59.280 --> 0:09:01.480 this anyway? So uh yeah, you you're not gonna think 0:09:01.520 --> 0:09:03.800 today anyway because you're hungover. So we're just gonna go 0:09:03.880 --> 0:09:08.360 ahead and uh shrink your brain here. Also, because you've 0:09:08.400 --> 0:09:11.360 been a p machine again thanks to that directic effect 0:09:11.360 --> 0:09:14.640 of alcohol. If you've lost potassium, sodium, and glucose, which 0:09:14.640 --> 0:09:17.200 we know as a source of energy and all, this 0:09:17.280 --> 0:09:20.640 can result in fatigue nausea and motor skills pross of 0:09:20.720 --> 0:09:24.120 saik a toddler. Well, what was that last part that 0:09:24.240 --> 0:09:27.120 you could have the motor skills pross of a talking essentially, 0:09:27.160 --> 0:09:30.520 because you know you have your you know, woken up 0:09:30.520 --> 0:09:33.120 in the morning and a night of debauchery and said 0:09:33.160 --> 0:09:35.480 to yourself, Oh, that's awful. You managed to get your 0:09:35.520 --> 0:09:37.240 head up off the pillow and then you just start 0:09:37.280 --> 0:09:40.040 banging into door frames everywhere. Well that's me all the 0:09:40.040 --> 0:09:42.199 time anyway, and not the debauchery part, but just waking 0:09:42.280 --> 0:09:47.560 up and stumbling over things. Okay, well made worse by alcohol. Yeah, yeah, 0:09:48.040 --> 0:09:51.120 I'm a klutz anyway, so if I was, if I'm hungover, 0:09:51.160 --> 0:09:53.600 then God help me. Another thing you have to worry 0:09:53.640 --> 0:09:57.720 about when you have alcohol. It's something called the congenera effect. 0:09:57.840 --> 0:10:02.560 And congenders are byproducts of fermentation in some alcohols. Uh, 0:10:02.720 --> 0:10:06.360 you'll encounter these and generally red wines and dark liquors 0:10:06.400 --> 0:10:09.440 such as your bourbons, your brandise, your whiskey, enough, your tequila. 0:10:09.520 --> 0:10:13.640 These are just additional toxins that can have various effects 0:10:13.640 --> 0:10:16.400 on the body. Right, And Okay, the the darker the 0:10:16.400 --> 0:10:20.040 alcohol like rum or red wine, the more congenerous are 0:10:20.080 --> 0:10:23.040 in it. So if you've got white wine or vodka, 0:10:23.080 --> 0:10:26.920 you're actually going to be imbibing less congenerous, which is 0:10:27.000 --> 0:10:29.959 a good thing. In fact, there was one study that 0:10:30.000 --> 0:10:32.480 said that thirty three of those who drink an amount 0:10:32.480 --> 0:10:35.960 of bourbon relative to their body weight reported a severe hangover, 0:10:36.080 --> 0:10:38.400 compared to three percent of those who drink the same 0:10:38.440 --> 0:10:41.400 amount of vodka. Not to say that clear liquors is 0:10:41.200 --> 0:10:45.120 a path to salvation, because because ever clear is pure 0:10:45.200 --> 0:10:47.160 looking at the driven snow, but everyone knows that it's 0:10:47.200 --> 0:10:52.280 brewed in the devil's vowels, so nicely put yeah, yeah, um. 0:10:52.320 --> 0:10:53.960 And then we know, of course that mixing is a 0:10:53.960 --> 0:10:56.160 bad idea, right right, Yeah. I like that they have 0:10:56.240 --> 0:10:59.520 all the things right, like beer before wine, go to bed, 0:10:59.559 --> 0:11:03.800 fine line before beer, nothing to fear. I'm right now. 0:11:03.960 --> 0:11:05.400 I can't remember one of them is bad, but I 0:11:05.440 --> 0:11:08.760 don't remember which. At any rate, they say, don't mix, right. 0:11:09.240 --> 0:11:11.640 If you're if you're having a margarite, to stick to marguarite. 0:11:11.640 --> 0:11:13.920 If you're having read wine, stick to red wine. Don't 0:11:13.960 --> 0:11:16.559 try and uh, you know, and earn all your merit 0:11:16.559 --> 0:11:18.920 badges in one night. That's right, because all those merit 0:11:18.920 --> 0:11:23.319 badges come with different points of toxicity, right, So you're 0:11:23.320 --> 0:11:26.080 basically just creating a little toxicity cocktail for your body 0:11:26.160 --> 0:11:29.559 to try to clean up the next day. Also, it 0:11:29.559 --> 0:11:32.200 should be noted carbonation, you know, such as you know 0:11:32.200 --> 0:11:35.840 in beer's, ciders, et cetera. These actually speed up the 0:11:35.880 --> 0:11:39.400 absorption of alcohol that's my body. So think about that. 0:11:39.520 --> 0:11:42.040 Is it fizzing? Is it dark? I don't know, you 0:11:42.360 --> 0:11:44.400 think twice maybe, because that's actually it's going to give 0:11:44.440 --> 0:11:47.760 the body less time and usual to process the toxins. Yeah, 0:11:48.240 --> 0:11:50.240 and there's nothing wrong with beer in and of itself, 0:11:50.280 --> 0:11:54.200 but pounding it several per hours probably not a good 0:11:54.240 --> 0:11:56.960 idea because it actually takes your body one hour process 0:11:57.080 --> 0:11:59.559 a drink like a beer, a glass of beer or 0:11:59.640 --> 0:12:02.520 a glass suppline. Well, you know what a houseman said 0:12:02.520 --> 0:12:04.600 about beer. What he said, beer has done more than 0:12:04.640 --> 0:12:08.280 Milton can to justify God's ways to man, I always 0:12:08.320 --> 0:12:10.880 like that one. He's of course referring to Milton, who 0:12:11.440 --> 0:12:14.760 paradise loss to justify the ways of god demands. So nice, 0:12:14.800 --> 0:12:16.760 that's just a little a set. I don't I'm actually 0:12:16.760 --> 0:12:18.440 not a beer drinker, but I like that quick you 0:12:18.480 --> 0:12:21.080 know that that that makes me think about when we 0:12:21.440 --> 0:12:23.760 can't remember which podcast it was, but we talked about 0:12:23.880 --> 0:12:26.800 how coffee houses really helped to usher in the age 0:12:26.840 --> 0:12:32.200 of enlightenment because before everyone has just drunk off their butts, right, 0:12:32.240 --> 0:12:36.240 because beer was sometimes more readily available than clean water. 0:12:36.760 --> 0:12:39.880 And so yeah, you know, put a little caffeine and 0:12:39.920 --> 0:12:41.559 then and all of a sudden people perk up and 0:12:41.760 --> 0:12:44.520 the ideas start flowing. So yeah, and also it was 0:12:44.559 --> 0:12:46.200 the you know, it's an age like you don't like 0:12:46.280 --> 0:12:47.960 your current state. It's like, I don't really like where 0:12:48.000 --> 0:12:49.560 my mind's at. I want to change it. What should 0:12:49.600 --> 0:12:52.600 I do? Well, there's the beer option, and then there's nothing, 0:12:52.679 --> 0:12:54.520 so I better go with the beer option. Now there 0:12:54.559 --> 0:12:56.360 are a lot more options. There's there's the upper and 0:12:56.400 --> 0:12:59.440 the downer, there's the coffee, there's the drink. People began 0:12:59.520 --> 0:13:01.920 to go more and more with the upper, with the 0:13:01.920 --> 0:13:05.320 coffee especially. Yeah, and then, of course we won't talk 0:13:05.360 --> 0:13:06.679 about it right now, but a little bit we'll talk 0:13:06.720 --> 0:13:09.520 about why you actually shouldn't mix you're caffeine with your alcohol. 0:13:10.440 --> 0:13:13.960 But let's talk about something that is quite a menace. 0:13:14.080 --> 0:13:17.320 It is as hyde. It's it's quite a bogger, right, 0:13:17.400 --> 0:13:19.319 It's a it's creative when alcohol and the liver is 0:13:19.360 --> 0:13:23.640 broken down, and it's more toxic than alcohol itself, and 0:13:23.760 --> 0:13:26.880 usually the toxin is neutralized when it bonds to substances 0:13:26.920 --> 0:13:31.000 called glutathione and nasatelda hide de hydrogen ase. But when 0:13:31.080 --> 0:13:34.680 large amounts of alcohol enter the system, liver stores of 0:13:34.720 --> 0:13:38.200 glutathion quickly run out and causes astel to hide, to 0:13:38.240 --> 0:13:40.320 build up in the body and linger for for long 0:13:40.400 --> 0:13:44.240 periods of time. Okay, so that's why, um, this is 0:13:44.280 --> 0:13:46.880 really important because you just have a finite store of 0:13:47.000 --> 0:13:49.720 basically these other little agents that come in and they 0:13:49.760 --> 0:13:52.400 are the clamp crew and they whisk everything away. So 0:13:52.679 --> 0:13:55.000 the more alcohol you pour into that, the more you're 0:13:55.000 --> 0:13:58.439 going to deplete the clean up agents. And that's when 0:13:58.480 --> 0:14:00.800 you get into trouble because you've got the acetelda hide 0:14:00.880 --> 0:14:03.439 just sitting there and storing up. So it also turns 0:14:03.480 --> 0:14:06.160 out that women have less stores of glutoth ione and 0:14:06.200 --> 0:14:10.040 acetel to hide dehydrogen ese, which makes their hangover to 0:14:10.080 --> 0:14:12.080 worse because it takes longer for the body to break 0:14:12.080 --> 0:14:14.880 down the alcohol. In case anybody's wondering, I know, sometimes 0:14:14.880 --> 0:14:16.640 people think that it has to do with body weight, 0:14:16.679 --> 0:14:19.600 and you know, certainly that is a factor. But the 0:14:19.640 --> 0:14:23.160 reason why women are essentially lightweights is because they don't 0:14:23.200 --> 0:14:26.480 have as much as that cleanup crew hanging out in 0:14:26.480 --> 0:14:30.080 their liver. It's also worth noting that sistine alright, cisticine 0:14:30.160 --> 0:14:33.000 is actually hanging out with the glutoth ione and helps 0:14:33.000 --> 0:14:36.280 to clean up. Yea, eggs contain a large amount of it. Yeah, 0:14:36.320 --> 0:14:38.040 so if you the whole thing about have a big 0:14:38.080 --> 0:14:42.040 breakfast after you had a night of drinking, Yeah, there's 0:14:42.080 --> 0:14:44.080 some truth to that because I think you know, big 0:14:44.080 --> 0:14:45.480 plate of eggs is going to have a lot of 0:14:45.600 --> 0:14:47.880 sustaining in it, right, and that will help kind of 0:14:47.920 --> 0:14:50.520 whisk it all out of your system. Um, but let's 0:14:50.560 --> 0:14:53.600 talk about this this last element which is really important 0:14:53.600 --> 0:14:58.200 about what's happening inside your body. Glutamine rebound. Yes, this 0:14:58.320 --> 0:15:01.240 is basically the the idea that uh that you've been 0:15:01.320 --> 0:15:04.520 you've been taking into pressant all night in the form 0:15:04.560 --> 0:15:06.600 of the alcohol, and then once you get home, you've 0:15:06.600 --> 0:15:09.960 stopped drinking, you want to sleep, but your body is 0:15:10.000 --> 0:15:13.480 now rebounding from all that depression. That's right. I'll call 0:15:13.520 --> 0:15:16.120 it inhibiting gluta mine, which is one of the body's 0:15:16.200 --> 0:15:18.960 natural stimulants. So when the drinker stops drinking and the 0:15:18.960 --> 0:15:21.520 body tries to make up for the lost time by 0:15:21.560 --> 0:15:24.400 producing more glutamen, and the net net is that your 0:15:24.400 --> 0:15:28.800 brain is really busy trying to recalibrate your body and 0:15:28.920 --> 0:15:32.120 therefore not resting during sleep. Right It's kind of like 0:15:32.280 --> 0:15:35.720 the cat has been sleeping all day, all afternoon while 0:15:35.720 --> 0:15:37.840 you've been running around. Now you want to sleep, but 0:15:37.920 --> 0:15:41.640 now the cat is awake. In the brain is the 0:15:41.680 --> 0:15:44.880 cat and it wants to play with a mouse right now. 0:15:45.480 --> 0:15:48.720 But yeah, I mean that's what leads to tremors, anxiety. 0:15:48.760 --> 0:15:53.840 This just general feeling of malai's restlessness and increase blood pressure, 0:15:53.840 --> 0:15:56.440 which is really important I think for people understand if 0:15:56.440 --> 0:15:59.480 they've got some risk factors there. And of course we 0:15:59.520 --> 0:16:03.240 need to talk about poopy tubes. I'm talking about diarrhea. Yes, 0:16:03.280 --> 0:16:05.520 what's the what's the rationale on this? Why should that 0:16:05.560 --> 0:16:07.960 have anything to do with like, because I mean it 0:16:09.080 --> 0:16:11.200 seems on one level, it's like this shouldn't really concern 0:16:11.240 --> 0:16:15.080 you intestines. This is this is just between my my, 0:16:15.080 --> 0:16:19.080 my brain, my liver, and my bladder. Like you you 0:16:19.080 --> 0:16:21.000 shouldn't even be a part of this discussion. Why are 0:16:21.080 --> 0:16:24.840 you butting in? Okay, because the stommic the intestines are like, hey, 0:16:24.880 --> 0:16:28.760 I've been poisoned, essentially because the alcohol is absorbed through 0:16:28.800 --> 0:16:31.480 the stomach lining and then those cells become irritated, right, 0:16:31.520 --> 0:16:33.480 and they just want to get everything out there, like 0:16:33.560 --> 0:16:35.760 something is wrong here. Let's just clear it out. Yeah, 0:16:35.800 --> 0:16:37.560 let's just go ahead and dump it all out. Also, 0:16:37.920 --> 0:16:41.480 alcohol promote secretion of hydrochloric acid in the stomach um, 0:16:41.480 --> 0:16:43.560 eventually causing the nerves to send a message to the 0:16:43.640 --> 0:16:46.160 brain that the stomachs contents are hurting the body and 0:16:46.640 --> 0:16:50.880 must be expelled through vomit. Okay, okay, So that's why 0:16:50.920 --> 0:16:54.120 sometimes people are clutching out the porcelain. God. Yeah, And 0:16:54.160 --> 0:16:56.040 it's it's like when you if you have any kind 0:16:56.080 --> 0:16:58.400 of like food poisoning situation, it's like the bodies like 0:16:58.440 --> 0:17:02.160 something ain't working. Everybody the out the front, out the back, 0:17:02.680 --> 0:17:04.959 I don't care. Whichever is easy is find the nearest exit. 0:17:05.240 --> 0:17:07.040 You you were you were told to note it when 0:17:07.080 --> 0:17:09.399 you entered the plane. Now it's time to leave. That's 0:17:09.440 --> 0:17:12.800 why we're shutting this down. Yeah, alright, So those are 0:17:12.800 --> 0:17:14.960 some of the basics about what's happening, these awful things 0:17:14.960 --> 0:17:16.720 that are happening in your body. We're going to talk 0:17:16.760 --> 0:17:19.840 about the I will never do that again syndrome a 0:17:20.000 --> 0:17:24.560 k a. Rose colored beer goggles. Rose colored beer goggles. Yes, 0:17:24.600 --> 0:17:28.479 now this is this is easy for anyone to imagine. 0:17:28.600 --> 0:17:30.399 Who's who's certainly who's ever had a little too much 0:17:30.440 --> 0:17:32.879 to drink, or even if you've just seen a TV 0:17:32.960 --> 0:17:35.040 show or a movie where someone has had too much 0:17:35.040 --> 0:17:37.520 to drink, there comes that that that moment in the 0:17:37.800 --> 0:17:40.679 morning after where someone's head feels like it's splitting in 0:17:40.760 --> 0:17:45.199 half or their their bodies evacuating at both ends. Uh, 0:17:45.520 --> 0:17:49.119 you know they're in a horrible state and they're clearly thinking, 0:17:49.200 --> 0:17:52.399 or you're clearly thinking, I Am never doing that again, 0:17:52.560 --> 0:17:55.840 because no matter how good it I felt last night, 0:17:55.880 --> 0:17:59.200 at any given moment, it's not worth how I'm feeling now. Yeah, 0:17:59.280 --> 0:18:02.680 it's true. For at least an hour up to possibly 0:18:02.760 --> 0:18:05.440 like I don't know, days, weeks, months afterward, you may 0:18:05.440 --> 0:18:09.280 be in this sort of shame spiral of I will 0:18:09.280 --> 0:18:12.520 never do that again, and I was a complete drunken 0:18:12.560 --> 0:18:16.719 stein um and you know it's it just never will 0:18:16.760 --> 0:18:18.960 happen again. I will never behave in such a way, 0:18:19.400 --> 0:18:22.399 and then it happens again. And this is very common, 0:18:22.480 --> 0:18:24.520 right yeah, I mean this. You can expand this out 0:18:24.560 --> 0:18:27.399 to anything humans do well. I mean I always keep 0:18:27.440 --> 0:18:30.000 making the same mistakes we never learned, and we are 0:18:30.040 --> 0:18:34.360 pretty bad at weighing long term effects versus instant gratification. 0:18:34.480 --> 0:18:37.679 Oh yeah, our ulysses packed with ourselves is usually no 0:18:37.760 --> 0:18:40.119 one void when it comes to alcohol. But just to 0:18:40.200 --> 0:18:42.200 throw some stats at you, more than seventy five of 0:18:42.240 --> 0:18:44.760 alcohol consumers have experienced to hang over at least once, 0:18:45.800 --> 0:18:48.720 have one at least every month. In percent of you 0:18:48.760 --> 0:18:52.480 crazy college students feel symptoms weekly, which is not a 0:18:52.520 --> 0:18:55.879 big surprise. So again, obviously people keep coming back to 0:18:55.920 --> 0:18:58.320 the trough when it comes to alcohol, and why do 0:18:58.359 --> 0:19:01.320 they do it? Positive memory bias. That's right. It turns 0:19:01.320 --> 0:19:03.720 out you are a very unreliable witness when it comes 0:19:03.720 --> 0:19:06.679 to you and drinking the previous nights bender might have 0:19:06.720 --> 0:19:10.320 seemed far more entertaining than it actually was, and you 0:19:10.440 --> 0:19:13.480 overrate the experience so that it now has a positive 0:19:13.560 --> 0:19:17.600 memory bias. Okay. Um. Researcher Diane Logan wrote a her 0:19:17.640 --> 0:19:21.240 findings in a paper for the Journal of Addictive Behavior, 0:19:21.320 --> 0:19:24.880 saying quote what goes on in some people's minds is, hey, 0:19:24.920 --> 0:19:27.120 I've learned my lesson, things will be better next time. 0:19:27.600 --> 0:19:31.160 Suddenly they think urinating on myself, it's not really that bad, 0:19:31.920 --> 0:19:36.000 and it's already happened a couple of times. Um, And 0:19:36.040 --> 0:19:39.560 this is what we call cognitive dissonance, right, yeah. Uh. 0:19:39.600 --> 0:19:41.600 And then again Logan says, it's kind of where the 0:19:41.640 --> 0:19:44.199 brain is at battle with itself. So if I'm a 0:19:44.320 --> 0:19:47.680 good upstanding person, those bad behaviors from the night before 0:19:47.840 --> 0:19:50.439 just don't quite fit together. Either I have to change 0:19:50.480 --> 0:19:53.840 my view of myself, which is really important with cognitive dissonance, right, 0:19:54.359 --> 0:19:56.160 or I have to change my view of the actual 0:19:56.200 --> 0:20:00.680 activity that occurred. So it's that changed battle we spoke 0:20:00.720 --> 0:20:03.919 of just ceases to exist because you can negate it 0:20:04.119 --> 0:20:08.080 by explaining away the events of your transgressions as saying, 0:20:08.359 --> 0:20:10.480 for instance, like, oh, well, that's just the cultural norm. 0:20:10.560 --> 0:20:13.920 This happens, right, peeing on yourself it happens. But I 0:20:13.960 --> 0:20:17.240 don't know that's actually I don't know how cultural norm 0:20:17.280 --> 0:20:20.000 that is. Well, I feel like it's more I mean, 0:20:20.160 --> 0:20:22.680 it's gonna happen, like you say, sooner or later, you're 0:20:22.680 --> 0:20:25.160 gonna be on yourself. There's no avoiding it. I kind 0:20:25.160 --> 0:20:27.680 of I'm gonna say a circumstance or another I was 0:20:27.720 --> 0:20:31.119 gonna say, perhaps this is a gender difference. Okay, I 0:20:31.160 --> 0:20:34.320 don't know. Um, So there you go. That's that's why 0:20:34.359 --> 0:20:36.720 we keep coming back to the alcohol trop or at 0:20:36.800 --> 0:20:38.480