WEBVTT - Listener Questions #29

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<v Speaker 1>Beetles and fungi are decimating trees in Seattle. Do any

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<v Speaker 1>other invertebrates ride fungi into battle?

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<v Speaker 2>How can the Ambi polar field ignore Earth's magnetic might?

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<v Speaker 2>And why is it stronger on Venus? Could it grow

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<v Speaker 2>here one night?

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<v Speaker 3>Is it true that stress can turn your hair gray?

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<v Speaker 3>My world is kind of a dumpster fire right now,

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<v Speaker 3>so I'd prefer if it didn't.

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<v Speaker 2>Okay, whatever questions keep you up at night, Daniel and

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<v Speaker 2>Kelly's answers will make it all right.

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<v Speaker 1>Welcome to another Daniel and Kelly's Extraordinary Universe, Another Listener

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<v Speaker 1>Questions episode.

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<v Speaker 3>We've done twenty nine of these.

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<v Speaker 2>You know, we haven't actually done twenty nine of these.

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<v Speaker 2>This is the twenty ninth.

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<v Speaker 3>We're doing the twenty ninth of these.

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<v Speaker 2>All right, So my question for you today, County is

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<v Speaker 2>when did you start to go gray?

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<v Speaker 4>Oh?

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<v Speaker 3>Man, gosh, A long time ago.

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<v Speaker 1>I started getting a few random grays towards like the

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<v Speaker 1>end of undergrad, I think, and then in grad school

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<v Speaker 1>it started speeding up. My mom started going gray at eighteen, wow,

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<v Speaker 1>And so I kind of anticipated it would happen, but

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<v Speaker 1>I didn't realize that I was really starting to go

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<v Speaker 1>gray until a friend of mine told me that I

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<v Speaker 1>was quote rocking the salt and pepper look, and I

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<v Speaker 1>gave him the stink eye because I thought of myself

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<v Speaker 1>as someone who had a few stray grays and I hadn't.

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<v Speaker 3>Realized I had transitioned to salt and pepper.

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<v Speaker 1>But it was very nice, and so I anyway, I

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<v Speaker 1>have transitioned to salt and pepper, apparently. And what about you,

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<v Speaker 1>I can't You've got You've got some grays, right, It's

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<v Speaker 1>hard to tell on the riverside camera.

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<v Speaker 2>I think I might have one or two gray beard hairs.

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<v Speaker 3>Daniel. That's not fair, I know.

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<v Speaker 2>But I think I'm still pretty much all original color

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<v Speaker 2>up top.

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<v Speaker 3>So wow, congratulations Daniel.

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<v Speaker 2>Yeah, well, there's some mythology in my family. My grandparents

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<v Speaker 2>on my dad's side both had jet black hair into

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<v Speaker 2>their eighties.

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<v Speaker 3>Wow.

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<v Speaker 2>But there's a discussion in the family about whether or

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<v Speaker 2>not they died it. Oh, And some people are like, oh,

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<v Speaker 2>of course they died it. How naive are you to

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<v Speaker 2>believe that an eighty year old had black hair? And

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<v Speaker 2>I don't know, maybe they did, who knows. I'm not

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<v Speaker 2>going to exhume their body and do.

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<v Speaker 5>Some tests scandalous, but so far.

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<v Speaker 2>In my personal experiment, no, gray's up top.

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<v Speaker 3>Yeah cool. I don't know. I don't really.

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<v Speaker 1>It doesn't keep me up at night that I have

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<v Speaker 1>gray hairs, like you know. I yes, I was a

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<v Speaker 1>little surprised, but mostly it's just because I'm not very

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<v Speaker 1>self aware. But at the end of the day, like

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<v Speaker 1>I don't care enough to diet or anything like that,

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<v Speaker 1>I'm not losing sleep.

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<v Speaker 2>And what comes after salt and pepper, before you're fully

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<v Speaker 2>silver haired? Is there another stage there?

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<v Speaker 3>I don't think so.

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<v Speaker 2>So once you're past salt and pepper, you're just all in.

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<v Speaker 1>I think then you're at silverfox ooh.

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<v Speaker 2>And then you go white and then you're Gandolf. Yeah.

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<v Speaker 3>I look forward to becoming Gandolf. I'll get there. The

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<v Speaker 3>white Wizard.

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<v Speaker 2>Well, that's the thing is people are like, oh, you

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<v Speaker 2>haven't turned gray yet, But I think gray adds gravitas.

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<v Speaker 2>It's nice for people to think you're younger than you are,

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<v Speaker 2>but then it also makes them take you less seriously sometimes. Yeah,

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<v Speaker 2>but something that I do want to take very seriously

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<v Speaker 2>are the questions in the minds of our listeners. Because

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<v Speaker 2>our goal is to give you a tour of everything

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<v Speaker 2>that's extraordinary in the universe, but not just the things

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<v Speaker 2>that we find extraordinary, the mysteries that tackle your minds.

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<v Speaker 2>So if you have questions about how the universe works,

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<v Speaker 2>please write to us two questions at danieland Kelly dot org.

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<v Speaker 2>Today's questions were taken directly from those.

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<v Speaker 1>Messages, and you'll see that Daniel wasn't just gloating at

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<v Speaker 1>the beginning of today's episode, although that might have been

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<v Speaker 1>part of it. We did get a question about graying

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<v Speaker 1>hair towards the end.

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<v Speaker 2>Bumble.

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<v Speaker 3>No, that was just bragging, just straight bragging. There was

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<v Speaker 3>nothing humble in there.

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<v Speaker 1>So all right, so let's move on to question one

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<v Speaker 1>from Eric, and let's go ahead and hear that question.

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<v Speaker 3>Now, hey, they're extraordinaries.

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<v Speaker 1>Eric and I had some technical difficulties, so I'm going

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<v Speaker 1>to go ahead and read his question and rest assured

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<v Speaker 1>the answer has already been shared with Eric. The question

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<v Speaker 1>is regarding the spruce bark beetle in Alaska and their

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<v Speaker 1>relationship with fungus. I understand that they're born with the

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<v Speaker 1>fungus which is parasitic to spruce trees, which knocks back

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<v Speaker 1>the immune response of the trees to resist the beetle.

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<v Speaker 1>The Beatles are a delivery mechanism for the fungus. Is

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<v Speaker 1>this relationship unique to beetles?

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<v Speaker 2>So he spells beatle b e a t l E.

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<v Speaker 2>Is he talking about the insect or the rock band.

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<v Speaker 1>I am going to go ahead and assume that that

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<v Speaker 1>was an auto correct because when I was going ahead

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<v Speaker 1>and taking notes a couple times, my phone and Google

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<v Speaker 1>Docs auto corrected to the band spelling. I guess the

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<v Speaker 1>band is much more popular than the invertebrates.

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<v Speaker 2>Well, but there are more kinds of beatles the invertebrates

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<v Speaker 2>than beatles the singers.

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<v Speaker 1>Right, So yep, yep, many many, Yes, there's I think

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<v Speaker 1>you know, there's probably something like six thousand bark beetles species,

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<v Speaker 1>and there's yeah, far fewer Beatle members.

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<v Speaker 2>And you're not prepared to answer the question if the

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<v Speaker 2>context were rock musicians.

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<v Speaker 3>Yeah, no, that's right.

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<v Speaker 1>Although I did just listen to the Rest is History

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<v Speaker 1>did a few series on the Beatles, but no, I'm

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<v Speaker 1>probably not prepared for a whole Beatles episode.

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<v Speaker 2>All right, So tell us about the bark beetles and

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<v Speaker 2>the relationship with spruce trees.

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<v Speaker 1>Okay, so there's a lot of different species of bark beetles,

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<v Speaker 1>and some of them kill tree and recently there have

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<v Speaker 1>been some mass tree dieoffs as a result of bark beetles.

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<v Speaker 5>They're so sad.

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<v Speaker 1>Yeah, But so you know, a lot of the beetles

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<v Speaker 1>that are causing these die offs are native, which I

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<v Speaker 1>think makes the story a little complicated. So, for example,

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<v Speaker 1>in Alaska, you have this spruce beetle. It's native and

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<v Speaker 1>usually it goes after unhealthy trees, and when its population

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<v Speaker 1>numbers are pretty low, it doesn't cause a lot of trouble,

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<v Speaker 1>Like it takes trees that were already kind of on

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<v Speaker 1>the way out, maybe hastens their demise a bit, but

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<v Speaker 1>that's not a big deal.

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<v Speaker 2>Do you mean it goes after the ones that are unhealthy,

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<v Speaker 2>like it knows or that it just has success against those?

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<v Speaker 3>Oh good question.

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<v Speaker 1>I don't know if it's specifically going after the unhealthy

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<v Speaker 1>ones or if it just is better at the unhealthy ones.

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<v Speaker 1>Because trees do have something like an immune system defense,

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<v Speaker 1>and as we're going to discuss in a moment here,

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<v Speaker 1>the beetles have a fungus that helps them with that

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<v Speaker 1>immune system defense. Amazing, Yeah, but it could be so

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<v Speaker 1>you know, the beatles. I don't think they're like randomly

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<v Speaker 1>blithely going about their life if not making any decisions.

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<v Speaker 1>I think they probably can to some extent tell if

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<v Speaker 1>they are near a tree that is going to be

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<v Speaker 1>easier or less easy to invade, And so probably they're

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<v Speaker 1>they're searching for the unhealthy ones that they'll have an

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<v Speaker 1>easier chance with. But at high population numbers, though, some

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<v Speaker 1>of those unhealthy ones might get crowded and they get

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<v Speaker 1>pushed out to healthy ones. Let's say that's what's happening, right,

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<v Speaker 1>And so when they get to really high population densities

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<v Speaker 1>and there's loads of these beetles all over the place,

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<v Speaker 1>they start killing the healthy trees too.

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<v Speaker 3>And so, for example, there's been.

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<v Speaker 1>An outbreak of these beetles in Alaska and something like

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<v Speaker 1>one point six million acres have been impacted, and that

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<v Speaker 1>means a bunch of yeah, many, many, many of these

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<v Speaker 1>native trees, native spruce trees have been killed in Alaska.

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<v Speaker 1>And there's another outbreak of the Eurasian spruce bark beetle

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<v Speaker 1>that's happening right now in Europe and it's decimating the

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<v Speaker 1>conifer forests. And so you know, as I mentioned, a

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<v Speaker 1>lot of these beetles are native, and so the question is,

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<v Speaker 1>you know, like I think a lot of us are

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<v Speaker 1>bummed out because we like forests.

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<v Speaker 5>And we like trees and living trees.

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<v Speaker 1>Living trees, right, and the idea that beetles are killing

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<v Speaker 1>a bunch of trees stinks. But I guess the question

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<v Speaker 1>is is this a natural process or not? So, you know,

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<v Speaker 1>when a bunch of trees die, they fall, and that

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<v Speaker 1>clears forest floor to suddenly get sunlight that wasn't getting

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<v Speaker 1>sunlight before because the trees were blocking it.

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<v Speaker 3>And now you can.

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<v Speaker 1>Get flowers and pollinators, and this is sort of how

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<v Speaker 1>ecosystems turn over. Ecosystems are not usually stagnant, and so

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<v Speaker 1>I guess the interesting question to me is is this

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<v Speaker 1>like a two hundred year cycle and we just kind

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<v Speaker 1>of weren't taking notes before and we're just seeing something

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<v Speaker 1>that naturally would have happened. Or would the two hundred

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<v Speaker 1>year cycle have included maybe like one hectare of trees

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<v Speaker 1>dying but because of global climate change or because we've

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<v Speaker 1>managed forests in a way that you know has made

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<v Speaker 1>more trees unhealthy, is it just way more intense than

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<v Speaker 1>it's ever in the past, in which case, you know,

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<v Speaker 1>maybe we care now because we have made this problem

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<v Speaker 1>much worse than it would have been.

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<v Speaker 2>Does that make sense, Yeah, But I had the impression

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<v Speaker 2>that some forests were truly ancient. You know that forests

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<v Speaker 2>can be fairly stable. If the climate is stable, et cetera,

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<v Speaker 2>then trees can grow for hundreds or thousands of years.

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<v Speaker 2>So it's not like there's a two hundred year cycle

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<v Speaker 2>where all the trees in the forest die and then

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<v Speaker 2>get replaced. And that's just what we're seeing, right. It

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<v Speaker 2>feels like we're seeing a shift in the capacity for

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<v Speaker 2>forests to exist. Right out here in the West, we

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<v Speaker 2>see lots and lots of dead trees on hillsides, and

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<v Speaker 2>it feels like, maybe you we're seeing the ends of forests.

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<v Speaker 1>Well, so, first of all, when I said two hundred,

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<v Speaker 1>I probably should have said x because I was just

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<v Speaker 1>picking a number. But so I was listening to Indefensive Plants,

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<v Speaker 1>which is a great plant podcast, and they had a

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<v Speaker 1>guy on there who studies bark beetles, and he was

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<v Speaker 1>saying that, like, you know, we really don't know if

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<v Speaker 1>this is a natural cycle or if it's something that's

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<v Speaker 1>getting much worse and we do think that probably it

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<v Speaker 1>is a problem that has gotten much worse. But for

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<v Speaker 1>a lot of the stuff, we don't have great data. Yeah,

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<v Speaker 1>because if X is a thousand and it's like a

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<v Speaker 1>thousand year cycle, we probably wouldn't have great data on that.

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<v Speaker 1>Maybe every one thousand years, you do expect to see

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<v Speaker 1>all the trees on the hillside's dead and then the

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<v Speaker 1>cycle starts again or something. But it wouldn't surprise me

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<v Speaker 1>to hear that we have made this problem worse through

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<v Speaker 1>global climate change and exacerbating drought and stuff like that.

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<v Speaker 1>But let's get back to the beetles in the fungus.

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<v Speaker 2>Yeah, so what are the beatles doing to the trees

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<v Speaker 2>and how does the fungus help?

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<v Speaker 1>Okay, so the beatles arrive at a tree and they

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<v Speaker 1>like you know, for example, they might go under the

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<v Speaker 1>bark and the adults might move around under the bark.

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<v Speaker 1>And when they do that, they introduce a fungus. And

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<v Speaker 1>this fungus the only way it can get from like

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<v Speaker 1>tree to tree is it travels with the beetles, and

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<v Speaker 1>so that's how the beetles benefit the fungus.

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<v Speaker 3>So then the fungus.

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<v Speaker 1>Infects the tree and it does a couple different things

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<v Speaker 1>for the beetles. One of the things that it does

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<v Speaker 1>is that the tree has a bunch of chemical defenses

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<v Speaker 1>that it would use to make the beetles sick and

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<v Speaker 1>kill them. And the fungus takes those chemicals that the

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<v Speaker 1>tree was using to defend itself and it neutralizes those chemicals,

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<v Speaker 1>so the tree is no longer toxic.

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<v Speaker 3>To the beetles. Amazing, totally agree. Yeah, it's crazy.

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<v Speaker 1>And now instead the beetle is starting to convert stuff

0:11:08.320 --> 0:11:10.920
<v Speaker 1>in the tree to stuff that's nutritious for the beetles.

0:11:10.920 --> 0:11:12.760
<v Speaker 1>So now it's easier for the beetles to get nutrition

0:11:12.880 --> 0:11:15.760
<v Speaker 1>from the tree. The beetles aren't getting attacked by the tree.

0:11:16.040 --> 0:11:18.560
<v Speaker 1>In some cases, the beetles are actually converting some of

0:11:18.559 --> 0:11:21.439
<v Speaker 1>the things that the tree makes into pheromones to attract

0:11:21.559 --> 0:11:24.400
<v Speaker 1>more beetles to the tree. Wow, I know, it's crazy.

0:11:24.800 --> 0:11:27.920
<v Speaker 1>And so then the beetles lay their eggs in the tree.

0:11:28.520 --> 0:11:31.000
<v Speaker 1>And you know, if you've worked with like trees before,

0:11:31.040 --> 0:11:33.480
<v Speaker 1>maybe sometimes you've pulled a piece of bark off and

0:11:33.559 --> 0:11:36.040
<v Speaker 1>underneath you've seen all of these sort of like almost

0:11:36.120 --> 0:11:38.840
<v Speaker 1>random lines that chriss cross over each other. Those are

0:11:38.880 --> 0:11:42.000
<v Speaker 1>the paths of like little baby beetles that have hatched

0:11:42.040 --> 0:11:44.320
<v Speaker 1>and sort of moved around, and it's like the path

0:11:44.360 --> 0:11:46.079
<v Speaker 1>of the food that they ate and the movements that

0:11:46.120 --> 0:11:46.439
<v Speaker 1>they made.

0:11:46.559 --> 0:11:49.200
<v Speaker 2>Yeah, like these little tunnels that they've dug through underneath

0:11:49.200 --> 0:11:50.880
<v Speaker 2>the bark. Yeah, it's very cool to see.

0:11:51.040 --> 0:11:53.440
<v Speaker 1>Yeah, they're called galleries, and I do feel like they're

0:11:53.440 --> 0:11:56.000
<v Speaker 1>little works of art, Like I love that name for them.

0:11:56.400 --> 0:11:58.760
<v Speaker 1>And so anyway, this reproduction keeps happening, and with this

0:11:58.800 --> 0:12:01.880
<v Speaker 1>collaboration between the beetle and the fungus, the beetles are

0:12:01.880 --> 0:12:05.400
<v Speaker 1>able to overwhelm the tree's defenses and they can kill

0:12:05.520 --> 0:12:06.199
<v Speaker 1>the tree that way.

0:12:06.440 --> 0:12:08.920
<v Speaker 2>And is this something that happens to trees worldwide? This

0:12:09.040 --> 0:12:11.880
<v Speaker 2>must be a common pattern between beetles and trees. I

0:12:11.920 --> 0:12:14.599
<v Speaker 2>remember seeing these kinds of patterns on the back of

0:12:14.720 --> 0:12:17.680
<v Speaker 2>bark of like Ponderosa pines in New Mexico, for example.

0:12:18.120 --> 0:12:20.760
<v Speaker 1>Yeah, so lots of trees have bark beetles, like at

0:12:20.800 --> 0:12:23.439
<v Speaker 1>least one bark beetles species. Sometimes you can find more

0:12:23.480 --> 0:12:27.280
<v Speaker 1>than one beetle species living in different parts of trees.

0:12:27.920 --> 0:12:31.040
<v Speaker 3>Not all of them are super bad for the tree.

0:12:31.080 --> 0:12:33.080
<v Speaker 1>And again, a lot of times it depends on how

0:12:33.120 --> 0:12:35.640
<v Speaker 1>many beetles there are, how bad the condition of the

0:12:35.640 --> 0:12:38.080
<v Speaker 1>tree is. But yeah, you can find these almost all

0:12:38.120 --> 0:12:40.480
<v Speaker 1>over the world. It seems to particularly be a problem

0:12:40.480 --> 0:12:42.800
<v Speaker 1>for like spruces and pines and stuff.

0:12:43.200 --> 0:12:45.280
<v Speaker 2>Is it ever good for the tree? Are they doing

0:12:45.360 --> 0:12:46.319
<v Speaker 2>anything that's helpful.

0:12:46.600 --> 0:12:49.640
<v Speaker 1>I didn't come across examples of that in my reading.

0:12:50.080 --> 0:12:52.760
<v Speaker 1>Oh yeah, it doesn't mean it's not out there. I

0:12:52.800 --> 0:12:55.440
<v Speaker 1>didn't read every paper on bark beetles, as you can imagine,

0:12:55.480 --> 0:12:57.440
<v Speaker 1>with over six thousand species, there's a lot of papers

0:12:57.440 --> 0:12:57.880
<v Speaker 1>out there.

0:12:58.440 --> 0:13:00.240
<v Speaker 2>Well, I don't know why, but I feel my self

0:13:00.320 --> 0:13:02.800
<v Speaker 2>rooting for the trees. I mean, I'm not the lorax

0:13:02.920 --> 0:13:05.680
<v Speaker 2>or anything, and beetles have just as much a right

0:13:05.720 --> 0:13:08.720
<v Speaker 2>to live and to eat as trees do. But it

0:13:08.760 --> 0:13:11.880
<v Speaker 2>feels like, you know, the trees have this grandeur and

0:13:11.920 --> 0:13:14.959
<v Speaker 2>they're supposed to be there, and the beetles are invading whatever.

0:13:15.400 --> 0:13:18.160
<v Speaker 2>So give me a more ecological viewpoint on this. Why

0:13:18.160 --> 0:13:21.000
<v Speaker 2>should I not be attached to the trees or should I?

0:13:21.280 --> 0:13:23.439
<v Speaker 1>Yeah, I think you could argue either way. Like, I mean,

0:13:23.480 --> 0:13:26.079
<v Speaker 1>I'm attached to the trees, and when the trees die,

0:13:26.320 --> 0:13:28.600
<v Speaker 1>then the like you know, the woodpeckers that we're living

0:13:28.640 --> 0:13:30.679
<v Speaker 1>in there, don't have a home anymore, and like all

0:13:30.760 --> 0:13:33.000
<v Speaker 1>of the other organisms that depended on those trees are

0:13:33.040 --> 0:13:35.920
<v Speaker 1>in trouble. Yeah, you know, I think it makes sense

0:13:35.920 --> 0:13:38.280
<v Speaker 1>that we get sort of emotionally attached to those forests

0:13:38.320 --> 0:13:40.960
<v Speaker 1>and all the organisms that live in there. But you know,

0:13:41.040 --> 0:13:44.240
<v Speaker 1>the only constant and life is change, and ecosystems do

0:13:44.600 --> 0:13:48.400
<v Speaker 1>pretty regularly turn from one thing to another, and so

0:13:49.960 --> 0:13:52.679
<v Speaker 1>you know, expecting a system to stay exactly the same

0:13:53.160 --> 0:13:55.720
<v Speaker 1>can cause problems. So, like one problem that humans have

0:13:55.800 --> 0:13:59.120
<v Speaker 1>caused is we've tried to suppress fires because we thought, well,

0:13:59.160 --> 0:14:01.640
<v Speaker 1>fires are bad, but now we've let fuels build up

0:14:01.880 --> 0:14:03.880
<v Speaker 1>over time, and now there's tons of fuel and so

0:14:03.920 --> 0:14:06.240
<v Speaker 1>when you do get a fire, it burns extra super

0:14:06.280 --> 0:14:09.520
<v Speaker 1>hot and it kills everything, whereas before there were some

0:14:09.600 --> 0:14:11.960
<v Speaker 1>species that would have survived a fire that didn't burn

0:14:12.040 --> 0:14:14.000
<v Speaker 1>quite as hot. And so, you know, we kind of

0:14:14.000 --> 0:14:15.880
<v Speaker 1>mess things up when we tinker with it. So the

0:14:16.000 --> 0:14:18.680
<v Speaker 1>question is should we tinker with this spark beetle situation?

0:14:19.160 --> 0:14:21.800
<v Speaker 1>And can we tinker with this bark beetle situation? Like

0:14:21.840 --> 0:14:25.240
<v Speaker 1>what could you even do? They're living under the bark,

0:14:25.400 --> 0:14:26.920
<v Speaker 1>and like, you know, what can you do that would

0:14:26.960 --> 0:14:30.440
<v Speaker 1>target the beetles or their fungus without messing with the

0:14:30.480 --> 0:14:31.480
<v Speaker 1>rest of the ecosystem.

0:14:31.560 --> 0:14:32.920
<v Speaker 3>Like, it's a really tough problem.

0:14:33.120 --> 0:14:34.520
<v Speaker 1>And I don't want to make it sound like I'm

0:14:34.520 --> 0:14:36.800
<v Speaker 1>saying we should throw up our arms and not do

0:14:36.920 --> 0:14:39.680
<v Speaker 1>anything ever, but just that, you know, these are complicated

0:14:39.680 --> 0:14:41.960
<v Speaker 1>problems that you need to think about from multiple angles.

0:14:42.320 --> 0:14:45.280
<v Speaker 2>Yeah, And I definitely have emotional connections to some parts

0:14:45.280 --> 0:14:47.880
<v Speaker 2>of the ecosystem, you know, like anything that threatens my

0:14:48.000 --> 0:14:50.240
<v Speaker 2>children for example. Oh yeah, you know, I'm not just

0:14:50.280 --> 0:14:51.520
<v Speaker 2>going to be like that it's in the way of

0:14:51.600 --> 0:14:54.440
<v Speaker 2>coyotes to tear out the throats of my children. Like,

0:14:54.880 --> 0:14:57.920
<v Speaker 2>you know, I'm definitely stepping in there and doing something wild.

0:14:58.040 --> 0:15:02.520
<v Speaker 1>Note that that one. We got an email from PETA

0:15:02.720 --> 0:15:05.880
<v Speaker 1>encouraging us to think about things from the animal standpoint.

0:15:06.000 --> 0:15:08.720
<v Speaker 1>A while back, and when I moved out to the

0:15:08.760 --> 0:15:10.880
<v Speaker 1>middle of nowhere, I did do a lot of research

0:15:10.960 --> 0:15:12.520
<v Speaker 1>on whether or not it was safe to let my

0:15:12.600 --> 0:15:15.440
<v Speaker 1>like three year olds outside with coyotes. I was outside

0:15:15.480 --> 0:15:18.200
<v Speaker 1>with my three year olds, and it is very rare

0:15:18.320 --> 0:15:20.280
<v Speaker 1>for a coyote to go after a three year old.

0:15:20.320 --> 0:15:22.640
<v Speaker 1>But you are encouraged to stay with your three year

0:15:22.680 --> 0:15:26.120
<v Speaker 1>olds outside if there's coyotes around. But once they get bigger,

0:15:26.400 --> 0:15:28.480
<v Speaker 1>the coyotes are very unlikely to go after them. So

0:15:28.560 --> 0:15:32.000
<v Speaker 1>your children are safe from coyotes at this age, I

0:15:32.000 --> 0:15:32.720
<v Speaker 1>would suspect.

0:15:32.920 --> 0:15:36.480
<v Speaker 2>I hope that's true. Just two days ago, my daughter

0:15:36.520 --> 0:15:38.880
<v Speaker 2>called me because she was out walking our dog and

0:15:38.920 --> 0:15:41.240
<v Speaker 2>there was a coyote that blocked her on a path

0:15:41.400 --> 0:15:42.920
<v Speaker 2>and she was like, I don't know what to do.

0:15:43.640 --> 0:15:46.160
<v Speaker 2>So I biked over there and made my presence known.

0:15:46.360 --> 0:15:49.240
<v Speaker 1>Oh wait, and so you had to scare the coyote away? Yeah,

0:15:49.320 --> 0:15:49.840
<v Speaker 1>oh wow.

0:15:50.760 --> 0:15:53.720
<v Speaker 2>Yeah. They are very brazen in our neighborhood now. They

0:15:53.880 --> 0:15:56.600
<v Speaker 2>roam in packs, they're everywhere, and hey, you know, we

0:15:56.640 --> 0:15:59.720
<v Speaker 2>moved into their neighborhood. So on the other hand, I

0:15:59.720 --> 0:16:02.080
<v Speaker 2>don't really want them eating my kids or my dog.

0:16:02.360 --> 0:16:02.680
<v Speaker 3>Yeah.

0:16:02.720 --> 0:16:04.920
<v Speaker 2>But back to the question at hand, we're talking about

0:16:04.960 --> 0:16:08.600
<v Speaker 2>fungi and beetles. One question I had is these beetles

0:16:08.640 --> 0:16:12.560
<v Speaker 2>are using the fungus to help colonize the tree. What's

0:16:12.600 --> 0:16:14.720
<v Speaker 2>in it for the fungus and what's happening when the

0:16:14.720 --> 0:16:17.240
<v Speaker 2>beetles are not in a tree, or are the beetles

0:16:17.280 --> 0:16:18.440
<v Speaker 2>never not in a tree?

0:16:18.680 --> 0:16:20.920
<v Speaker 1>The beetles are pretty much always in a tree or

0:16:21.040 --> 0:16:24.320
<v Speaker 1>moving from one tree to another, and the fungus get transport.

0:16:24.520 --> 0:16:26.080
<v Speaker 1>So the best way for the fungus to get from

0:16:26.080 --> 0:16:29.040
<v Speaker 1>one tree to another is by being moved by the fungus.

0:16:29.240 --> 0:16:31.120
<v Speaker 1>That's the main thing we think that they get from it.

0:16:31.480 --> 0:16:33.800
<v Speaker 2>Okay, and are beetles the only ones who do this

0:16:33.880 --> 0:16:34.920
<v Speaker 2>kind of fungus farming?

0:16:35.520 --> 0:16:35.760
<v Speaker 3>No?

0:16:36.120 --> 0:16:36.480
<v Speaker 5>Really?

0:16:36.600 --> 0:16:38.920
<v Speaker 1>Yeah, So Eric wanted to know, you know what other

0:16:39.040 --> 0:16:43.600
<v Speaker 1>invertebrates collaborate with fungi, And it turns out that there's

0:16:43.720 --> 0:16:46.880
<v Speaker 1>quite a few invertebrates that collaborate with fungus, and so

0:16:47.080 --> 0:16:51.800
<v Speaker 1>fungus farming is a pretty common thing in the invertebrate world. Daniel,

0:16:51.800 --> 0:16:55.040
<v Speaker 1>I have a question for you termites. You look at termites,

0:16:55.320 --> 0:16:57.720
<v Speaker 1>what do you think termites are closely related to If.

0:16:57.640 --> 0:17:00.480
<v Speaker 5>You had to guess, hmmm, termite.

0:17:00.160 --> 0:17:01.560
<v Speaker 3>Or do you already know the answer to this?

0:17:01.840 --> 0:17:04.600
<v Speaker 2>I do not know the answer. Okay, they're an insect

0:17:04.680 --> 0:17:07.560
<v Speaker 2>because of the legs they got all those little segments,

0:17:07.960 --> 0:17:10.119
<v Speaker 2>they seem kind of antie to me, thank you.

0:17:10.640 --> 0:17:12.480
<v Speaker 3>Yes, they do look anti to me.

0:17:13.560 --> 0:17:15.439
<v Speaker 1>And so I said something to one of my friends

0:17:15.440 --> 0:17:17.240
<v Speaker 1>about them being, you know, kind of ant like, and

0:17:17.280 --> 0:17:21.800
<v Speaker 1>they were like, Kelly, they're more closely related to cockroaches what.

0:17:22.920 --> 0:17:24.520
<v Speaker 1>And I looked at them for a second and I

0:17:24.800 --> 0:17:26.280
<v Speaker 1>kind of gave them a little bit of the stink

0:17:26.240 --> 0:17:29.120
<v Speaker 1>guy because I was like, you are either messing with

0:17:29.160 --> 0:17:33.320
<v Speaker 1>me or I should be very embarrassed because I.

0:17:33.280 --> 0:17:35.760
<v Speaker 3>Am way off here. And it turned out I was

0:17:35.800 --> 0:17:36.200
<v Speaker 3>way off.

0:17:36.320 --> 0:17:38.080
<v Speaker 2>Well, I don't have to be embarrassed because I'm not

0:17:38.080 --> 0:17:40.520
<v Speaker 2>supposed to know so well.

0:17:40.560 --> 0:17:42.200
<v Speaker 1>Yeah, and I wasn't trying to embarrass you like you

0:17:42.240 --> 0:17:44.119
<v Speaker 1>were trying to embarrass me about my gray hair earlier.

0:17:44.160 --> 0:17:48.840
<v Speaker 2>But ooh, life, I'm impressed by the gravitas your gray

0:17:48.880 --> 0:17:49.639
<v Speaker 2>hair lends to you.

0:17:49.880 --> 0:17:53.080
<v Speaker 1>Oh thank you. Yes, I looked very mature and commanding

0:17:53.200 --> 0:17:59.320
<v Speaker 1>of wisdom and whatnot. Exactly all right. So, fungus farming

0:17:59.840 --> 0:18:04.600
<v Speaker 1>is seen in some termites, ants, wood wasps, and ambrosia beetles.

0:18:04.640 --> 0:18:07.640
<v Speaker 1>So basically the deal here is that they collect certain

0:18:07.680 --> 0:18:11.280
<v Speaker 1>kinds of fungus. They put fungus in a certain area. Sometimes,

0:18:11.520 --> 0:18:14.320
<v Speaker 1>for example, there are like leafcutter ants who will feed

0:18:14.359 --> 0:18:16.920
<v Speaker 1>the fungus certain kinds of leaves, and then the fungus

0:18:16.960 --> 0:18:20.840
<v Speaker 1>will break it down into things that are more digestible

0:18:21.000 --> 0:18:23.600
<v Speaker 1>for you know, for example, the leaf cutter ants. So

0:18:23.680 --> 0:18:26.359
<v Speaker 1>let's talk about the Ambrosia beetles for a second. So

0:18:26.440 --> 0:18:30.280
<v Speaker 1>the Ambrosia beetles will farm fungus and they will bring

0:18:30.320 --> 0:18:35.240
<v Speaker 1>them into for example, like dead trees, and then they'll

0:18:35.280 --> 0:18:38.200
<v Speaker 1>create those galleries that we were talking about, and they'll

0:18:38.200 --> 0:18:40.280
<v Speaker 1>sort of lay their eggs, they'll have their babies, and

0:18:40.320 --> 0:18:42.960
<v Speaker 1>the fungus will be like creating food for everybody. And

0:18:43.000 --> 0:18:46.280
<v Speaker 1>the Ambrosia beetles even have little specialized parts on their

0:18:46.280 --> 0:18:48.680
<v Speaker 1>body so that they can carry the fungus with them

0:18:49.119 --> 0:18:51.680
<v Speaker 1>from one place to another. And so this is like

0:18:51.720 --> 0:18:54.400
<v Speaker 1>a very close symbiosis, so they can, you know, can

0:18:54.400 --> 0:18:56.280
<v Speaker 1>bring it from one place to another. But while I

0:18:56.359 --> 0:19:02.560
<v Speaker 1>was reading about this, I discovered a cool concept called micocleptism.

0:19:03.359 --> 0:19:08.120
<v Speaker 1>And so while some Ambrosia beetles will bring the fungus

0:19:08.160 --> 0:19:10.840
<v Speaker 1>with them from place to place and will essentially live

0:19:10.880 --> 0:19:13.520
<v Speaker 1>with the same strains of fungus for their whole lives,

0:19:14.320 --> 0:19:18.000
<v Speaker 1>other beetles will steal fungus from others. And so there

0:19:18.040 --> 0:19:20.720
<v Speaker 1>are some beetle species who will find an Ambrosia beetle

0:19:20.760 --> 0:19:23.240
<v Speaker 1>who's doing a good job of farming their own fungus.

0:19:23.240 --> 0:19:26.600
<v Speaker 1>They're being good farmers, good stewards of the land, and

0:19:26.640 --> 0:19:30.879
<v Speaker 1>then the micocleptics will will come in and they'll steal

0:19:30.920 --> 0:19:33.119
<v Speaker 1>some of the fungus and they'll start farming it on

0:19:33.200 --> 0:19:35.320
<v Speaker 1>a different part of the log, kind of close by.

0:19:35.400 --> 0:19:38.720
<v Speaker 1>They'll lay their own eggs in there, and they'll essentially

0:19:38.960 --> 0:19:42.040
<v Speaker 1>steal the fungus. And so they don't they're not born

0:19:42.119 --> 0:19:45.000
<v Speaker 1>with this fungus. They take it from another organism over

0:19:45.040 --> 0:19:45.840
<v Speaker 1>the course of their lives.

0:19:46.560 --> 0:19:48.440
<v Speaker 2>Wow, that's a little creepy.

0:19:48.520 --> 0:19:49.440
<v Speaker 3>It's a little creepy.

0:19:49.560 --> 0:19:51.919
<v Speaker 1>Yeah, yeah, it it'd be like your family stealing beans

0:19:51.920 --> 0:19:56.480
<v Speaker 1>from another family or something, you know, because you guys

0:19:56.520 --> 0:19:58.879
<v Speaker 1>have a close symbiosis with beans and chia seeds.

0:20:00.600 --> 0:20:03.159
<v Speaker 2>That's true, we do. We are lovers of fermented foods

0:20:03.160 --> 0:20:25.720
<v Speaker 2>and fiber. Over here. Mm hmm, Okay, we're back and

0:20:25.760 --> 0:20:30.240
<v Speaker 2>we're answering questions from listeners today. Questions about Beatles, questions

0:20:30.280 --> 0:20:35.160
<v Speaker 2>about space, questions about what's going on on Kelly's cranium.

0:20:34.640 --> 0:20:37.280
<v Speaker 1>On my cranium. How did we get to talking about

0:20:37.320 --> 0:20:38.080
<v Speaker 1>my cranium?

0:20:38.119 --> 0:20:40.440
<v Speaker 2>Are we going to be talking about gray hair, salt

0:20:40.480 --> 0:20:41.800
<v Speaker 2>and pepper silver foxes later?

0:20:42.000 --> 0:20:44.280
<v Speaker 1>Oh yeah, okay, we're back. We're back to my gray hair,

0:20:44.320 --> 0:20:46.000
<v Speaker 1>so we're going to talk about my crow's feet too.

0:20:46.240 --> 0:20:48.960
<v Speaker 1>Is there anything else you want to point out that's

0:20:49.000 --> 0:20:49.480
<v Speaker 1>wrong with me?

0:20:49.600 --> 0:20:49.959
<v Speaker 3>Daniel?

0:20:50.440 --> 0:20:52.639
<v Speaker 2>I never noticed any crows feed, Kelly. This is the

0:20:52.640 --> 0:20:53.600
<v Speaker 2>first I hear about them.

0:20:53.680 --> 0:20:54.479
<v Speaker 3>No, no, you're not.

0:20:54.560 --> 0:20:58.600
<v Speaker 1>You can't walk back the problem you started earlier today, Daniel.

0:21:01.200 --> 0:21:04.000
<v Speaker 1>All right, let's change the subject and hear what Gene

0:21:04.040 --> 0:21:04.680
<v Speaker 1>has to say.

0:21:06.680 --> 0:21:10.199
<v Speaker 6>Hi there, Daniel and Kelly. I've recently heard about the

0:21:10.240 --> 0:21:14.159
<v Speaker 6>Ambi polar field and I'm fascinated to know more. It

0:21:14.200 --> 0:21:17.760
<v Speaker 6>seems to be independent of the earth magnetic field, but

0:21:17.840 --> 0:21:21.320
<v Speaker 6>I don't understand how that can be. Can you explain.

0:21:22.240 --> 0:21:25.680
<v Speaker 6>I've also heard that the field is much stronger on Venus,

0:21:26.200 --> 0:21:30.119
<v Speaker 6>and that's one reason why Venus no longer has oxygen

0:21:30.240 --> 0:21:35.080
<v Speaker 6>or hydrogen in its atmosphere. But why is it stronger

0:21:35.280 --> 0:21:39.280
<v Speaker 6>on Venus than on Earth? And was it always that strong?

0:21:39.840 --> 0:21:44.080
<v Speaker 6>If not, might it increase on Earth. I'm loving the

0:21:44.119 --> 0:21:47.560
<v Speaker 6>show and being able to ask questions. It's like having

0:21:47.640 --> 0:21:51.320
<v Speaker 6>a tame professor in the spare room. So I'm really

0:21:51.320 --> 0:21:55.199
<v Speaker 6>looking forward to hearing your answers to my questions. Thank you.

0:21:55.920 --> 0:21:59.120
<v Speaker 2>All right, So Gene has a really fun question about

0:21:59.200 --> 0:22:02.439
<v Speaker 2>electric and meg magnetic fields around the Earth. And this

0:22:02.480 --> 0:22:04.399
<v Speaker 2>is a field I think a lot of people haven't

0:22:04.440 --> 0:22:04.800
<v Speaker 2>heard of.

0:22:05.160 --> 0:22:07.800
<v Speaker 1>Yeah, I don't think that I've heard, or if I have,

0:22:07.840 --> 0:22:10.480
<v Speaker 1>I've forgotten about the ambu polar field. Right, So I'm

0:22:10.480 --> 0:22:13.760
<v Speaker 1>thinking about ambidextrous and you can switch between left and right.

0:22:14.280 --> 0:22:17.040
<v Speaker 1>Is that Is that helping me understand ambipolar because it can?

0:22:17.160 --> 0:22:20.640
<v Speaker 3>It's okay.

0:22:20.760 --> 0:22:24.800
<v Speaker 2>So most people are familiar with Earth's gravitational field right.

0:22:24.920 --> 0:22:27.760
<v Speaker 2>In a Newtonian picture, gravity is a force and it

0:22:27.840 --> 0:22:30.720
<v Speaker 2>polls on stuff, and things with more masks get pulled

0:22:30.720 --> 0:22:33.680
<v Speaker 2>on more strongly, and that's what holds the atmosphere in place,

0:22:33.800 --> 0:22:38.040
<v Speaker 2>for example, or Earth's magnetic field. Magnetic fields are generated

0:22:38.080 --> 0:22:41.720
<v Speaker 2>by charges in motion, So like currents of magma and

0:22:41.840 --> 0:22:44.800
<v Speaker 2>other metals inside the Earth we think generate the magnetic

0:22:44.800 --> 0:22:48.480
<v Speaker 2>field not fully understood with all sorts of weird behavior

0:22:48.600 --> 0:22:50.639
<v Speaker 2>like the poles move and the poles flip, all this

0:22:50.760 --> 0:22:54.960
<v Speaker 2>kind of stuff. The ambipolar field is something completely separate

0:22:55.000 --> 0:22:58.879
<v Speaker 2>from both of those. It's a totally separate effect coming

0:22:58.880 --> 0:23:01.800
<v Speaker 2>from atoms in the app hemosphere being ionized.

0:23:02.280 --> 0:23:03.440
<v Speaker 3>Ah All right, So.

0:23:03.400 --> 0:23:05.480
<v Speaker 1>Is this going to have anything to do with the

0:23:05.560 --> 0:23:06.760
<v Speaker 1>Aurora borealis.

0:23:07.640 --> 0:23:11.440
<v Speaker 2>Not directly, no, but a little bit, yeah, a little bit.

0:23:11.880 --> 0:23:14.960
<v Speaker 2>So what happens is if you have a neutral particle,

0:23:15.240 --> 0:23:18.240
<v Speaker 2>like if a proton and an electron they're bound together,

0:23:18.400 --> 0:23:22.480
<v Speaker 2>they make hydrogen for example, everything is happy, but sometimes

0:23:22.480 --> 0:23:25.800
<v Speaker 2>things get hot and electrons leave their protons, and now

0:23:25.840 --> 0:23:29.720
<v Speaker 2>you have ions protons that are positively charged and electrons

0:23:29.840 --> 0:23:32.879
<v Speaker 2>electrons are negatively charged, and they're separated. So this is

0:23:32.920 --> 0:23:35.359
<v Speaker 2>like a plasma. And in the upper atmosphere you have

0:23:35.440 --> 0:23:38.360
<v Speaker 2>high speeds and not everything is bound together. So there's

0:23:38.400 --> 0:23:41.600
<v Speaker 2>lots of protons and electrons up there, not just all

0:23:41.680 --> 0:23:45.040
<v Speaker 2>neutral atoms. So now you have the gravitational force. It's

0:23:45.040 --> 0:23:47.560
<v Speaker 2>going to pull harder on the protons than it is

0:23:47.560 --> 0:23:51.120
<v Speaker 2>on the electrons. Why because protons are much more massive

0:23:51.440 --> 0:23:52.400
<v Speaker 2>than the electrons.

0:23:52.560 --> 0:23:54.320
<v Speaker 5>M hm, I remember that, mm hm.

0:23:55.000 --> 0:23:57.640
<v Speaker 2>And so what that means is that protons are lower

0:23:57.640 --> 0:24:00.720
<v Speaker 2>in the atmosphere than electrons. You get this because the

0:24:00.720 --> 0:24:03.960
<v Speaker 2>electrons are lower mass, they're moving faster with the same

0:24:04.040 --> 0:24:08.200
<v Speaker 2>kinetic energy. So essentially you get an imbalance. Right now,

0:24:08.240 --> 0:24:11.480
<v Speaker 2>you have the electrons higher up than the protons. That

0:24:11.480 --> 0:24:14.760
<v Speaker 2>creates an electric field because you have these charged particles,

0:24:15.080 --> 0:24:17.280
<v Speaker 2>and when you create a separation of charges, you get

0:24:17.320 --> 0:24:20.040
<v Speaker 2>a field between them because essentially there's a force that

0:24:20.080 --> 0:24:23.080
<v Speaker 2>wants to pull them back. That is an electric field.

0:24:23.160 --> 0:24:26.800
<v Speaker 2>The Ambi polar field in the upper atmosphere of Earth

0:24:26.840 --> 0:24:29.719
<v Speaker 2>and also Mars and also Venus. So that's what the

0:24:29.760 --> 0:24:31.200
<v Speaker 2>Ambi polar field is.

0:24:31.560 --> 0:24:34.119
<v Speaker 3>WHOA Okay, all right? So first of all, can you

0:24:34.240 --> 0:24:35.200
<v Speaker 3>use that for anything?

0:24:36.800 --> 0:24:38.919
<v Speaker 2>You can use it to create like a gun of

0:24:38.960 --> 0:24:43.360
<v Speaker 2>particles out into space. So for example, this field will

0:24:43.440 --> 0:24:46.960
<v Speaker 2>pull on particles, it'll pull protons up, and in some

0:24:47.000 --> 0:24:49.520
<v Speaker 2>parts of the Earth it'll create like a polar fountain,

0:24:49.840 --> 0:24:51.479
<v Speaker 2>and like at the North Pole it creates like a

0:24:51.520 --> 0:24:56.320
<v Speaker 2>font of hydrogen atoms, hydrogen ions actually shooting up and

0:24:56.440 --> 0:24:58.879
<v Speaker 2>out of the Earth. I don't know if that's useful

0:24:58.880 --> 0:24:59.520
<v Speaker 2>for anything, but.

0:24:59.480 --> 0:25:02.720
<v Speaker 3>It's kind of okay, yep needs And you could also.

0:25:02.600 --> 0:25:06.760
<v Speaker 2>In principle use it to help like steer satellites. You know,

0:25:07.119 --> 0:25:10.879
<v Speaker 2>there's one way to steer satellites instead of having thrusters.

0:25:11.359 --> 0:25:14.200
<v Speaker 2>You used to like use the Earth's electric and magnetic fields.

0:25:14.200 --> 0:25:16.159
<v Speaker 2>Like you have a long tether and you twist it

0:25:16.200 --> 0:25:18.440
<v Speaker 2>and that creates torque or you can use it to

0:25:18.480 --> 0:25:21.720
<v Speaker 2>create thrust. It's fairly weak though, so not like big

0:25:21.760 --> 0:25:23.920
<v Speaker 2>satellites or anything. But you know, it adds to this

0:25:24.040 --> 0:25:26.560
<v Speaker 2>sort of texture of the near Earth environment.

0:25:26.840 --> 0:25:30.320
<v Speaker 1>Okay, awesome, And then okay, so you so Earth, Mars,

0:25:30.400 --> 0:25:32.560
<v Speaker 1>and Venus have it all, right, So what are they are?

0:25:32.720 --> 0:25:35.840
<v Speaker 1>So they all have gravity, but every planet has gravity.

0:25:36.320 --> 0:25:40.639
<v Speaker 1>They all have atmospheres, So you need an atmosphere.

0:25:39.960 --> 0:25:43.320
<v Speaker 2>Although Mars's atmosphere is much much weaker, so its ambipolar

0:25:43.400 --> 0:25:44.600
<v Speaker 2>field is also weaker.

0:25:44.800 --> 0:25:46.720
<v Speaker 3>Yeah, and Mars is like what one percent of Earth's

0:25:46.800 --> 0:25:47.160
<v Speaker 3>or something.

0:25:47.320 --> 0:25:48.000
<v Speaker 2>Yeah, exactly.

0:25:48.280 --> 0:25:50.320
<v Speaker 1>Is that all you need is a gravitational field and

0:25:50.359 --> 0:25:52.639
<v Speaker 1>an atmosphere to have an ambipolar field.

0:25:52.880 --> 0:25:55.359
<v Speaker 2>That's almost all you need. You need ions in your

0:25:55.400 --> 0:25:58.320
<v Speaker 2>atmosphere also, right, If it's all neutral particles, you're not

0:25:58.359 --> 0:26:01.000
<v Speaker 2>going to get an ambipolar field. And that's one reason

0:26:01.000 --> 0:26:04.359
<v Speaker 2>why Venus has a much stronger ambipolar field than Earth

0:26:04.640 --> 0:26:07.600
<v Speaker 2>Number one has a very dense atmosphere, so there's a

0:26:07.640 --> 0:26:10.560
<v Speaker 2>lot of electrons and ions to pull apart. But also

0:26:11.080 --> 0:26:14.520
<v Speaker 2>because Venus has no magnetic field, it has no protection

0:26:14.640 --> 0:26:16.720
<v Speaker 2>from the solar wind. See we're going to get to

0:26:16.720 --> 0:26:19.879
<v Speaker 2>the Aurora Borealis connection, and the solar wind is what

0:26:19.960 --> 0:26:22.760
<v Speaker 2>creates a lot of these ions in the upper atmosphere.

0:26:23.160 --> 0:26:26.200
<v Speaker 2>So you have energy from space photons and protons, etc.

0:26:26.600 --> 0:26:30.400
<v Speaker 2>Hitting the upper atmosphere that ionizes it. That energy from

0:26:30.440 --> 0:26:33.520
<v Speaker 2>space breaks open neutral atoms to create your ion and

0:26:33.560 --> 0:26:37.320
<v Speaker 2>your electron. And because Venus doesn't have a magnetic field

0:26:37.359 --> 0:26:39.600
<v Speaker 2>to protect it from the solar wind, a lot of

0:26:39.640 --> 0:26:43.439
<v Speaker 2>that solar radiation causes more ionization and speeds up those

0:26:43.520 --> 0:26:46.399
<v Speaker 2>particles because all this energy is coming from space, and

0:26:46.440 --> 0:26:48.560
<v Speaker 2>so that gives you a lot of ions, and those

0:26:48.600 --> 0:26:51.920
<v Speaker 2>ions are now moving fast, and so that helps these

0:26:51.920 --> 0:26:55.800
<v Speaker 2>ions escape. So that creates a very strong ambipolar field

0:26:55.920 --> 0:26:58.879
<v Speaker 2>on Venus. And this is always sort of counterintuitive, like

0:26:59.000 --> 0:27:02.480
<v Speaker 2>the electrons get high high, the protons get lower, and

0:27:02.520 --> 0:27:05.480
<v Speaker 2>so that's the amberpolar field. But then the effect on

0:27:05.520 --> 0:27:09.080
<v Speaker 2>the other particles is the opposite. That field is always

0:27:09.080 --> 0:27:12.399
<v Speaker 2>trying to cancel itself out. Electromagnetism is always doing whatever

0:27:12.440 --> 0:27:15.639
<v Speaker 2>it can to cancel itself out because it's so strong.

0:27:16.080 --> 0:27:18.919
<v Speaker 2>So you create that field by separating them. Then the

0:27:18.960 --> 0:27:21.520
<v Speaker 2>field has the effect of pushing the ions up and

0:27:21.560 --> 0:27:24.119
<v Speaker 2>the electrons down. Which is why you get this like

0:27:24.240 --> 0:27:27.760
<v Speaker 2>font of hydrogen ions. In a similar way sort of

0:27:27.760 --> 0:27:30.280
<v Speaker 2>that if you immerse a metal in an electric field,

0:27:30.560 --> 0:27:33.159
<v Speaker 2>the electrons in that metal will move to counter that

0:27:33.200 --> 0:27:37.760
<v Speaker 2>electric field because the electric field has pushed on those electrons. Right,

0:27:37.840 --> 0:27:40.480
<v Speaker 2>So electromagnetism is always doing everything it can to zero

0:27:40.560 --> 0:27:42.760
<v Speaker 2>itself out. Doesn't want to ever do anything. It's just

0:27:42.800 --> 0:27:43.359
<v Speaker 2>so lazy.

0:27:44.600 --> 0:27:49.360
<v Speaker 1>Okay, So it's stronger on Venus. So is it stronger

0:27:49.359 --> 0:27:53.120
<v Speaker 1>on Venus for two reasons? One Venus has a thicker

0:27:53.160 --> 0:27:57.000
<v Speaker 1>atmosphere and two you're more likely to have charged particles

0:27:57.040 --> 0:27:58.040
<v Speaker 1>in that atmosphere.

0:27:58.160 --> 0:28:01.720
<v Speaker 2>Yes, exactly. So it's not directly connected to the magnetic field.

0:28:01.720 --> 0:28:04.480
<v Speaker 2>It's not caused by the magnetic field in that sense.

0:28:04.560 --> 0:28:07.240
<v Speaker 2>I think that was Jane's question. But it is indirectly

0:28:07.240 --> 0:28:10.680
<v Speaker 2>connected because the magnetic field will help you prevent ionization

0:28:10.720 --> 0:28:14.040
<v Speaker 2>of your upper atmosphere, which would reduce the amber polar field.

0:28:14.440 --> 0:28:17.800
<v Speaker 2>And so Venus has a strong one because two reasons, Yes,

0:28:17.960 --> 0:28:20.640
<v Speaker 2>has a denser atmosphere and it doesn't have protection from

0:28:20.680 --> 0:28:23.640
<v Speaker 2>the solar radiation. Now, we think that a long time

0:28:23.680 --> 0:28:26.960
<v Speaker 2>ago Venus was a very different situation. It might have

0:28:27.080 --> 0:28:30.879
<v Speaker 2>had a magnetic field before its internal bits seized up

0:28:30.920 --> 0:28:33.560
<v Speaker 2>and it cooled. It might have had internal motion which

0:28:33.640 --> 0:28:37.520
<v Speaker 2>generated a magnetic field which shielded it from some solar radiation,

0:28:37.960 --> 0:28:40.720
<v Speaker 2>which would have had less ionization. Now it's lost on

0:28:40.800 --> 0:28:43.880
<v Speaker 2>magnetic field, so it gets more radiation and a stronger.

0:28:43.440 --> 0:28:49.760
<v Speaker 1>Field cool Okay, Now, could Earth get a stronger ambipolar field.

0:28:50.080 --> 0:28:54.320
<v Speaker 2>Yes, it's possible that our ambipolar field could increase, but

0:28:54.400 --> 0:28:56.720
<v Speaker 2>for that to happen, we'd essentially have to lose our

0:28:56.840 --> 0:29:00.920
<v Speaker 2>magnetic field. We have to be more susceptible solar radiation,

0:29:01.680 --> 0:29:04.120
<v Speaker 2>so that could either be we lose our magnetic field,

0:29:04.320 --> 0:29:07.120
<v Speaker 2>which seems unlikely. I mean, we don't really understand it,

0:29:07.160 --> 0:29:09.560
<v Speaker 2>and it's been kind of flip flopping and slashing around.

0:29:09.840 --> 0:29:12.719
<v Speaker 2>But total loss of the magnetic field would require the

0:29:12.760 --> 0:29:15.800
<v Speaker 2>Earth's internal mechanisms to seize up the way Mars has

0:29:15.880 --> 0:29:18.920
<v Speaker 2>and Venus has, and that seems unlikely it happens soon

0:29:19.120 --> 0:29:22.040
<v Speaker 2>because there's still plenty of activity going on insider. If

0:29:22.040 --> 0:29:25.000
<v Speaker 2>it would happen, it would be slow and gradual. Or

0:29:25.120 --> 0:29:27.840
<v Speaker 2>the other thing is we could have more solar radiation,

0:29:28.240 --> 0:29:32.240
<v Speaker 2>so we could get more ionization, and that's more unpredictable

0:29:32.400 --> 0:29:34.760
<v Speaker 2>like that just depends on Hey, is the Sun gonna

0:29:34.760 --> 0:29:37.800
<v Speaker 2>burbt us some huge blob of plasma that comes and

0:29:37.840 --> 0:29:41.400
<v Speaker 2>strips away a lot of the atmosphere or ionizes it.

0:29:41.560 --> 0:29:43.960
<v Speaker 2>That could happen in any moment. You know, just a

0:29:43.960 --> 0:29:47.120
<v Speaker 2>few weeks ago we had really strong aurora boreality is

0:29:47.240 --> 0:29:50.120
<v Speaker 2>how you pluralize it. You could see them pretty far

0:29:50.280 --> 0:29:53.240
<v Speaker 2>south in the United States because of the space weather

0:29:53.280 --> 0:29:56.640
<v Speaker 2>event from the Sun, and that comes from not understanding

0:29:56.720 --> 0:29:59.320
<v Speaker 2>the internal dynamics and the chaos of the Sun's plasma

0:29:59.360 --> 0:30:02.040
<v Speaker 2>well enough to So, yeah, we could get a stronger

0:30:02.040 --> 0:30:05.440
<v Speaker 2>ambipolar field if we got more solar radiation or if

0:30:05.440 --> 0:30:07.719
<v Speaker 2>we weakened our protection from it. Either one would give

0:30:07.800 --> 0:30:10.960
<v Speaker 2>us more ions and therefore a stronger ambipolar field.

0:30:11.400 --> 0:30:13.920
<v Speaker 1>Neither one of those options sound great for the humans

0:30:14.000 --> 0:30:16.440
<v Speaker 1>living here, So let's hope it doesn't happen.

0:30:17.960 --> 0:30:20.360
<v Speaker 2>All right, Well, let's send that answer to Jane and

0:30:20.480 --> 0:30:22.560
<v Speaker 2>hear if it freaked her out or made her feel

0:30:22.560 --> 0:30:24.960
<v Speaker 2>more at one with her understanding.

0:30:24.400 --> 0:30:25.160
<v Speaker 5>Of the universe.

0:30:25.480 --> 0:30:28.040
<v Speaker 3>And let's hear if she's going to kick the professor

0:30:28.080 --> 0:30:29.080
<v Speaker 3>out of her spare room.

0:30:31.080 --> 0:30:34.080
<v Speaker 4>Thank you so much for your answer, Daniel, I really

0:30:34.080 --> 0:30:37.920
<v Speaker 4>feel I understand the ambipolar field now, and I'm very

0:30:37.920 --> 0:30:42.240
<v Speaker 4>relieved the way for the most part, protected from Venus's

0:30:42.280 --> 0:30:47.000
<v Speaker 4>fate by our wonderful magnetic field. But I do love

0:30:47.080 --> 0:30:51.240
<v Speaker 4>the idea of a polar fountain. Sounds like something Santa

0:30:51.320 --> 0:30:54.640
<v Speaker 4>would have. Oh, by the way, my spare room is

0:30:54.680 --> 0:30:57.640
<v Speaker 4>still available for professors if you're ever in the North

0:30:57.680 --> 0:31:00.160
<v Speaker 4>of England. Thanks for a great.

0:31:20.200 --> 0:31:21.680
<v Speaker 1>I don't know, Daniel, if you had a professor in

0:31:21.720 --> 0:31:24.720
<v Speaker 1>your spare room for questions, would you want a physicist

0:31:26.160 --> 0:31:28.200
<v Speaker 1>or maybe a less smelly profession.

0:31:29.320 --> 0:31:32.400
<v Speaker 2>We often have a professor in our spare room because

0:31:32.440 --> 0:31:34.840
<v Speaker 2>we have a guest room and people come to visit

0:31:35.080 --> 0:31:37.560
<v Speaker 2>and sometimes, you know, you invite a friend to come

0:31:37.560 --> 0:31:39.800
<v Speaker 2>and visit for official reasons to give a talk, but

0:31:39.800 --> 0:31:41.000
<v Speaker 2>then you also want to hang out with them and

0:31:41.000 --> 0:31:42.400
<v Speaker 2>you don't want to put them up in a hotel,

0:31:42.720 --> 0:31:44.400
<v Speaker 2>so they sleep in our spare room and have dinner

0:31:44.400 --> 0:31:46.640
<v Speaker 2>with us, and that's a lot of fun. So often

0:31:46.760 --> 0:31:51.320
<v Speaker 2>we have biologists and physicists or physicists usually coming to

0:31:51.360 --> 0:31:54.960
<v Speaker 2>stay with us, and our kids have expressed their lack

0:31:55.000 --> 0:31:59.480
<v Speaker 2>of enthusiasm for physics or biology dominated dinner conversations.

0:32:01.280 --> 0:32:03.440
<v Speaker 1>Our kids at some point asked us to please stop

0:32:03.440 --> 0:32:05.080
<v Speaker 1>talking about space law over dinner.

0:32:05.640 --> 0:32:09.280
<v Speaker 3>H Yeah, I understand. All right. Let's move on to

0:32:09.680 --> 0:32:11.040
<v Speaker 3>our question from Joe.

0:32:11.120 --> 0:32:14.040
<v Speaker 7>Hi, Danielle, and Kelly. I've often heard the claim that

0:32:14.160 --> 0:32:16.880
<v Speaker 7>stress made me get all these great hairs? Is there

0:32:16.920 --> 0:32:21.040
<v Speaker 7>any biological validity to that concept? And if so, what

0:32:21.120 --> 0:32:25.240
<v Speaker 7>are the mechanisms? Can your emotional state plus cortisol or

0:32:25.320 --> 0:32:30.000
<v Speaker 7>dopamine levels perhaps affect this part of your biology? Finally,

0:32:30.360 --> 0:32:33.560
<v Speaker 7>has it been observed in any other animals? Thanks so

0:32:33.640 --> 0:32:36.720
<v Speaker 7>much for bringing some color or salt and pepper to

0:32:36.800 --> 0:32:37.360
<v Speaker 7>this question.

0:32:37.640 --> 0:32:40.280
<v Speaker 2>All right, So Joe suggested, the gray hair isn't just

0:32:40.320 --> 0:32:43.080
<v Speaker 2>about age. It might be about stress. It's about like

0:32:43.200 --> 0:32:46.000
<v Speaker 2>emotional age, not you know, cosmological age.

0:32:46.160 --> 0:32:47.880
<v Speaker 1>That's right, and so I think it's possible that there

0:32:47.920 --> 0:32:50.800
<v Speaker 1>are different mechanisms at play here. So let's go ahead

0:32:50.840 --> 0:32:55.600
<v Speaker 1>and leave my old age related grays to the side.

0:32:55.640 --> 0:32:59.000
<v Speaker 1>We don't have to talk about them anymore. Actually, okay,

0:32:59.160 --> 0:33:03.200
<v Speaker 1>all right, and so to understand what's happening, let's go

0:33:03.200 --> 0:33:06.720
<v Speaker 1>ahead and talk about the hair cycle. All right, So

0:33:07.120 --> 0:33:10.440
<v Speaker 1>you have loads of hair follicles on your head?

0:33:10.640 --> 0:33:13.880
<v Speaker 2>I do you do you do one does.

0:33:13.760 --> 0:33:16.400
<v Speaker 1>Not only is your hair not gray, but you actually

0:33:17.040 --> 0:33:19.720
<v Speaker 1>have it covering your whole head. You are very lucky

0:33:19.760 --> 0:33:21.880
<v Speaker 1>for a fifty year old. Or are we rounding up

0:33:21.880 --> 0:33:22.440
<v Speaker 1>to one hundred?

0:33:22.480 --> 0:33:22.680
<v Speaker 5>Now?

0:33:23.600 --> 0:33:26.120
<v Speaker 2>Yeah, exactly, I'm more than fifty, so rounds up.

0:33:26.280 --> 0:33:27.000
<v Speaker 3>Okay, all right.

0:33:27.040 --> 0:33:30.400
<v Speaker 1>So each of our hair follicles goes through a cycle,

0:33:30.480 --> 0:33:33.600
<v Speaker 1>and our hair follicles aren't SYNCD, so our hair follicles

0:33:33.640 --> 0:33:37.320
<v Speaker 1>tend to be at different stages of this cycle. Anigen

0:33:38.040 --> 0:33:40.320
<v Speaker 1>is the part of the cycle where your hair is growing,

0:33:40.760 --> 0:33:42.400
<v Speaker 1>and for the hair on top of your head, the

0:33:42.440 --> 0:33:45.440
<v Speaker 1>stage usually lasts about four to six years.

0:33:45.800 --> 0:33:47.920
<v Speaker 5>Oh that's all yeah, yeah.

0:33:47.720 --> 0:33:50.200
<v Speaker 1>Kind of surprising, right, and your hair is growing something

0:33:50.320 --> 0:33:53.200
<v Speaker 1>like half an inch a year. And early in anigen,

0:33:53.400 --> 0:33:57.280
<v Speaker 1>what happens is that you have hair follicle stem cells,

0:33:57.280 --> 0:34:00.560
<v Speaker 1>and so stem cells our cells that are they're like

0:34:00.680 --> 0:34:02.040
<v Speaker 1>they're like baby stem cells.

0:34:02.040 --> 0:34:04.160
<v Speaker 3>There's things that they can become, but they haven't.

0:34:03.920 --> 0:34:06.840
<v Speaker 1>Become them yet. And these are cells that are going

0:34:06.880 --> 0:34:10.520
<v Speaker 1>to become hair follicles, but they haven't become them yet.

0:34:10.520 --> 0:34:12.920
<v Speaker 1>So they're hanging out there and when the time comes,

0:34:13.280 --> 0:34:16.080
<v Speaker 1>they will become hair follicles and they're just waiting for

0:34:16.120 --> 0:34:16.759
<v Speaker 1>the message.

0:34:17.080 --> 0:34:17.879
<v Speaker 3>When you get to this.

0:34:17.920 --> 0:34:22.080
<v Speaker 1>Early growth phase, these hairfollical stem cells jump into action.

0:34:22.520 --> 0:34:25.440
<v Speaker 1>They make a hair follicle, and now you've got your

0:34:25.480 --> 0:34:26.359
<v Speaker 1>hair follicle.

0:34:26.080 --> 0:34:28.360
<v Speaker 2>All right. So I have stem cells on my scalp

0:34:28.480 --> 0:34:31.680
<v Speaker 2>my whole life, waiting to become follicles. Mm hm, cool,

0:34:31.719 --> 0:34:32.200
<v Speaker 2>didn't know that.

0:34:32.480 --> 0:34:37.080
<v Speaker 1>And you also have melanocytes stem cells, and so what

0:34:37.239 --> 0:34:41.040
<v Speaker 1>they're doing is they're waiting to produce melanocytes. And these

0:34:41.080 --> 0:34:45.040
<v Speaker 1>are the cells that make melanin, which is the pigment

0:34:45.239 --> 0:34:50.040
<v Speaker 1>that gives hair color. And so early in anigen, your

0:34:50.120 --> 0:34:54.160
<v Speaker 1>hair follicle is being made, and your melanocyte stem cells

0:34:54.480 --> 0:34:59.400
<v Speaker 1>are activated to make melanocytes, and the melanocytes will travel

0:34:59.480 --> 0:35:02.560
<v Speaker 1>down to your hair follicle and they get ready to

0:35:02.600 --> 0:35:06.320
<v Speaker 1>start making melanin. So now your hair follicle is making

0:35:06.360 --> 0:35:09.680
<v Speaker 1>the hair, your melanocytes are making the melanin, and now

0:35:09.719 --> 0:35:11.720
<v Speaker 1>you have hair that has color.

0:35:12.000 --> 0:35:16.560
<v Speaker 2>And all of my melaninites have to all be coordinated, right,

0:35:16.640 --> 0:35:19.560
<v Speaker 2>because I have like one color of hair on my head,

0:35:19.719 --> 0:35:21.359
<v Speaker 2>and do you have a different color of hair? And

0:35:21.520 --> 0:35:24.760
<v Speaker 2>my daughter's blonde, for example, And so there's a genetic

0:35:24.800 --> 0:35:27.400
<v Speaker 2>coating in there. That controls all of the melaninites or

0:35:27.440 --> 0:35:29.040
<v Speaker 2>melanocytes melanocytes.

0:35:29.520 --> 0:35:31.080
<v Speaker 3>Yes, they're all making the same color.

0:35:31.400 --> 0:35:32.640
<v Speaker 5>I see. Yeah, Okay.

0:35:32.640 --> 0:35:34.960
<v Speaker 2>So the thing that's confusing to me is if they

0:35:35.000 --> 0:35:37.319
<v Speaker 2>only last for four to sixty years, how come I

0:35:37.320 --> 0:35:39.080
<v Speaker 2>didn't lose all my hair when I was seven?

0:35:39.400 --> 0:35:41.200
<v Speaker 3>Because there's a cycle.

0:35:41.200 --> 0:35:43.279
<v Speaker 1>Okay, So you've got four to six years, and then

0:35:43.360 --> 0:35:46.560
<v Speaker 1>you go into a phase called the catagen phase where

0:35:46.600 --> 0:35:50.239
<v Speaker 1>everything sort of degenerates. You lose the blood vessels and

0:35:50.280 --> 0:35:53.400
<v Speaker 1>so now the hair follicle isn't getting oxygen or nutrients,

0:35:53.760 --> 0:35:55.960
<v Speaker 1>and this lasts about two weeks. And at this stage

0:35:56.080 --> 0:36:01.920
<v Speaker 1>the melanocytes die, but your melanocytes stem cells are still alive,

0:36:02.880 --> 0:36:05.239
<v Speaker 1>so you still have cells that can make more melanocytes,

0:36:05.280 --> 0:36:07.319
<v Speaker 1>but the melanocytes that were made a few years ago

0:36:07.520 --> 0:36:08.120
<v Speaker 1>they're toast.

0:36:08.320 --> 0:36:09.080
<v Speaker 5>Okay, okay.

0:36:09.080 --> 0:36:11.440
<v Speaker 1>And then you go into a resting phase and this

0:36:11.440 --> 0:36:13.760
<v Speaker 1>can last for a few months where the hair follicles

0:36:13.800 --> 0:36:16.600
<v Speaker 1>just kind of chilling out, and then you go into

0:36:16.640 --> 0:36:21.160
<v Speaker 1>a phase called exigen where the original hair is shed

0:36:21.200 --> 0:36:24.080
<v Speaker 1>out because you've started the cycle again. A new hair

0:36:24.239 --> 0:36:27.320
<v Speaker 1>is growing and it pushes out the old one you shed,

0:36:27.440 --> 0:36:30.000
<v Speaker 1>So you shed something like fifty to one hundred hairs

0:36:30.040 --> 0:36:32.560
<v Speaker 1>a day, and so that's how many hairs are sort

0:36:32.560 --> 0:36:35.480
<v Speaker 1>of beginning the process anew. And when you start that

0:36:35.520 --> 0:36:39.000
<v Speaker 1>process ANEW, those two types of stem cells wake up again.

0:36:39.080 --> 0:36:41.799
<v Speaker 1>They start doing their jobs again. And after the new

0:36:41.840 --> 0:36:44.640
<v Speaker 1>hair follicle has started and after the new melanocytes are

0:36:44.760 --> 0:36:47.240
<v Speaker 1>have gone to work, those two sets of stem cells

0:36:47.320 --> 0:36:50.080
<v Speaker 1>go to sleep again for like, you know, four to

0:36:50.120 --> 0:36:52.440
<v Speaker 1>six years or whatever. They do their job, they make

0:36:52.440 --> 0:36:54.160
<v Speaker 1>the cells that are going to work through the cycle,

0:36:54.400 --> 0:36:55.840
<v Speaker 1>and then the stem cells go to sleep.

0:36:56.120 --> 0:36:56.920
<v Speaker 3>Does that make sense.

0:36:56.960 --> 0:36:58.560
<v Speaker 2>That makes a lot of sense, and it really helps

0:36:58.600 --> 0:37:01.640
<v Speaker 2>me understand something I remember wondering about when I was

0:37:01.680 --> 0:37:05.120
<v Speaker 2>like a teenager young physicist. Daniel was thinking about hair

0:37:05.160 --> 0:37:08.160
<v Speaker 2>growth the way you think about like radioactive decay. You know.

0:37:08.280 --> 0:37:11.040
<v Speaker 2>I was thinking maybe it was like probabilistic and hairs

0:37:11.080 --> 0:37:13.440
<v Speaker 2>would just like fall out randomly. But if that were

0:37:13.480 --> 0:37:15.040
<v Speaker 2>the case, you'd start with like a full head of

0:37:15.080 --> 0:37:17.840
<v Speaker 2>hair and then you just gradually lose hairs until eventually

0:37:17.880 --> 0:37:20.600
<v Speaker 2>you had like one super long hair, which would be

0:37:21.400 --> 0:37:24.880
<v Speaker 2>you had. Clearly, that model does not explain the data,

0:37:25.200 --> 0:37:26.719
<v Speaker 2>So I like your model a lot better.

0:37:26.960 --> 0:37:29.080
<v Speaker 1>Oh good, Okay, well, and there's a lot of variability.

0:37:29.160 --> 0:37:31.400
<v Speaker 1>Some people have you know, shorter cycles, so their hair

0:37:31.440 --> 0:37:33.759
<v Speaker 1>doesn't grow as long, right, and the cycle on your

0:37:33.800 --> 0:37:36.279
<v Speaker 1>body as much shorter, so your body hairs never get

0:37:36.320 --> 0:37:38.680
<v Speaker 1>as long as the hair is on your head. But

0:37:38.760 --> 0:37:40.839
<v Speaker 1>this is like sort of generally or understanding of how

0:37:40.880 --> 0:37:42.720
<v Speaker 1>the cycle goes on average.

0:37:42.400 --> 0:37:44.440
<v Speaker 2>All right, And so there's really two different bits there.

0:37:44.480 --> 0:37:47.640
<v Speaker 2>There's like the hair growing and the hair coloring, and

0:37:47.719 --> 0:37:50.680
<v Speaker 2>so tell us about why the hair coloring can go

0:37:50.760 --> 0:37:52.640
<v Speaker 2>wrong or why things turn gray?

0:37:52.760 --> 0:37:53.080
<v Speaker 3>All right?

0:37:53.120 --> 0:37:56.520
<v Speaker 1>So I found this amazing paper jang at All twenty

0:37:56.560 --> 0:38:00.560
<v Speaker 1>twenty in Nature did this amazing set of bar ORMs

0:38:00.600 --> 0:38:03.680
<v Speaker 1>that sort of like deal with tons of different hypotheses,

0:38:03.719 --> 0:38:05.360
<v Speaker 1>and they really nail it down in mice.

0:38:05.440 --> 0:38:07.120
<v Speaker 3>So again this is in mice. Keep in mind it's

0:38:07.160 --> 0:38:08.760
<v Speaker 3>in mice, not in humans.

0:38:08.800 --> 0:38:11.920
<v Speaker 1>But okay, so first they say if you stress out

0:38:11.960 --> 0:38:15.640
<v Speaker 1>black mice, will they get gray hairs? So they stress

0:38:15.680 --> 0:38:17.880
<v Speaker 1>mice out a couple different ways, and the mice do

0:38:18.040 --> 0:38:18.759
<v Speaker 1>start going gray.

0:38:18.960 --> 0:38:19.760
<v Speaker 2>Are they terrible?

0:38:20.239 --> 0:38:23.800
<v Speaker 1>Uh No, I mean they're not. They're not the worst

0:38:23.800 --> 0:38:24.680
<v Speaker 1>I've read about.

0:38:24.840 --> 0:38:27.120
<v Speaker 2>I have to imagine how I stress out a mouse.

0:38:27.520 --> 0:38:29.239
<v Speaker 2>I might like put it in a cage next to

0:38:29.280 --> 0:38:31.480
<v Speaker 2>a cat, not to kill it, but just to like

0:38:31.760 --> 0:38:33.439
<v Speaker 2>put it in the cage next to it. That would

0:38:33.440 --> 0:38:34.720
<v Speaker 2>be pretty stressful for a mouse.

0:38:34.880 --> 0:38:37.440
<v Speaker 3>Oh okay, So no, this is nowhere near that bad. Actually.

0:38:37.520 --> 0:38:41.040
<v Speaker 1>So they would rapidly change the light and dark cycles.

0:38:41.400 --> 0:38:43.960
<v Speaker 1>They would leave the bedding be a little bit damp,

0:38:44.080 --> 0:38:47.239
<v Speaker 1>they would have the cage be sort of tilted. They

0:38:47.360 --> 0:38:49.120
<v Speaker 1>leave them in a cage by themselves, and they're kind

0:38:49.120 --> 0:38:52.279
<v Speaker 1>of in a social species. So nowhere near as bad

0:38:52.440 --> 0:38:53.280
<v Speaker 1>as what you're thinking.

0:38:53.440 --> 0:38:55.160
<v Speaker 2>That's very gentle, Yes, that is yes.

0:38:55.200 --> 0:38:55.399
<v Speaker 3>Yeah.

0:38:55.400 --> 0:38:57.880
<v Speaker 1>And again, as we've discussed multiple times on the show,

0:38:58.040 --> 0:38:59.839
<v Speaker 1>before you do experiments like this, you need to get

0:39:00.000 --> 0:39:02.920
<v Speaker 1>animal care and use protocols. And we understand you have

0:39:03.000 --> 0:39:04.880
<v Speaker 1>to stress the animals out to test the hypothesis, but

0:39:04.920 --> 0:39:05.399
<v Speaker 1>you've got to.

0:39:05.320 --> 0:39:06.680
<v Speaker 3>Do it in the most human way possible.

0:39:06.880 --> 0:39:10.359
<v Speaker 1>Good okay, But the most effective and fast method they

0:39:10.400 --> 0:39:13.000
<v Speaker 1>found for stressing the animals out was to give them

0:39:13.239 --> 0:39:16.919
<v Speaker 1>an injection of a capsayasin analog under their skin.

0:39:17.040 --> 0:39:19.240
<v Speaker 3>So capsayasins spicy. That's spicy.

0:39:19.320 --> 0:39:21.280
<v Speaker 1>Yeah, that's the stuff that gives you the spicy feeling

0:39:21.280 --> 0:39:22.520
<v Speaker 1>if you're eating peppers or something.

0:39:22.840 --> 0:39:24.879
<v Speaker 2>So they would like internally pepper spray these mice.

0:39:25.080 --> 0:39:28.200
<v Speaker 1>Yeah, you always find the most horrible way to say

0:39:28.400 --> 0:39:31.360
<v Speaker 1>these things when we talk about animal studies. But I

0:39:31.440 --> 0:39:34.640
<v Speaker 1>am going to just use the phrase the injection for

0:39:34.680 --> 0:39:35.279
<v Speaker 1>the rest of.

0:39:35.200 --> 0:39:38.480
<v Speaker 2>This description, if that makes you feel better.

0:39:38.320 --> 0:39:39.960
<v Speaker 3>Kelly, all right, All right, Well, do you want to

0:39:40.000 --> 0:39:41.040
<v Speaker 3>know the answer to this or not?

0:39:41.400 --> 0:39:41.880
<v Speaker 2>Yes? I do?

0:39:42.080 --> 0:39:42.400
<v Speaker 5>Please?

0:39:42.520 --> 0:39:43.399
<v Speaker 3>Okay? You all right?

0:39:43.480 --> 0:39:46.880
<v Speaker 1>So they inject mice with this capsaiusin analog and the

0:39:46.920 --> 0:39:49.960
<v Speaker 1>mice did get gray, but they got like salt and

0:39:50.000 --> 0:39:53.359
<v Speaker 1>pepper gray like me. So it wasn't they didn't turn

0:39:53.400 --> 0:39:55.680
<v Speaker 1>completely gray. It wasn't patches. It was exactly what you

0:39:55.680 --> 0:39:59.560
<v Speaker 1>would expect if you had hair follicles on random cycles.

0:39:59.640 --> 0:40:01.160
<v Speaker 3>And some some of them started turning gray.

0:40:01.320 --> 0:40:03.400
<v Speaker 2>And did they look at the microbiology of it, like

0:40:03.480 --> 0:40:06.560
<v Speaker 2>can they see the melanocyte dying or doing something or.

0:40:06.480 --> 0:40:08.400
<v Speaker 1>Giving up or yeah, So that's the next thing that

0:40:08.400 --> 0:40:10.520
<v Speaker 1>they did. So next they said, okay, we know that

0:40:10.560 --> 0:40:12.399
<v Speaker 1>the we've got these mice that will turn gray sort

0:40:12.440 --> 0:40:14.200
<v Speaker 1>of like humans do, So what's happening. So then they

0:40:14.640 --> 0:40:16.680
<v Speaker 1>they decided they were gonna for the stress or they

0:40:16.680 --> 0:40:17.239
<v Speaker 1>were going to just.

0:40:17.280 --> 0:40:18.240
<v Speaker 3>Keep using this injection.

0:40:18.680 --> 0:40:21.080
<v Speaker 1>So then they used the injection and they looked at

0:40:21.080 --> 0:40:24.640
<v Speaker 1>what was happening with the melanocyte stem cells and with

0:40:24.719 --> 0:40:28.480
<v Speaker 1>the milano sites, and what they found was that the

0:40:28.520 --> 0:40:34.280
<v Speaker 1>melanocytes stem cells were like disappearing, oh, but the milana

0:40:34.440 --> 0:40:38.080
<v Speaker 1>sites were staying where they were, and so all of

0:40:38.160 --> 0:40:40.359
<v Speaker 1>the melanocytes that had already been made were fine. They

0:40:40.440 --> 0:40:43.520
<v Speaker 1>kept making the black pigment for these black mice, but

0:40:43.560 --> 0:40:46.319
<v Speaker 1>the milanocytes stem cells were gone. So the next time

0:40:46.400 --> 0:40:50.640
<v Speaker 1>a phase started again, no new melanocytes were made, and

0:40:50.680 --> 0:40:52.440
<v Speaker 1>those hair follicles would become gray.

0:40:52.640 --> 0:40:54.400
<v Speaker 2>So gray is the default color. If you don't have

0:40:54.440 --> 0:40:56.400
<v Speaker 2>a melanocyte, then it's just gray.

0:40:56.440 --> 0:40:59.480
<v Speaker 1>Yes, right, And so they're like, Okay, where did these

0:41:00.080 --> 0:41:02.680
<v Speaker 1>in a site stem cells go that are supposed to

0:41:03.520 --> 0:41:05.279
<v Speaker 1>be there to make sure you've got the cells to

0:41:05.280 --> 0:41:07.960
<v Speaker 1>give you color every time the cycle starts again. So

0:41:08.000 --> 0:41:09.840
<v Speaker 1>that was the next question that they wanted to ask.

0:41:10.320 --> 0:41:12.000
<v Speaker 1>And so one idea that's been going around for a

0:41:12.000 --> 0:41:14.120
<v Speaker 1>while is that when you get stressed out, something about

0:41:14.120 --> 0:41:19.680
<v Speaker 1>your immune system attacks your like hair follicles, and something

0:41:19.719 --> 0:41:21.919
<v Speaker 1>about that makes it so that your hair goes gray.

0:41:22.360 --> 0:41:25.040
<v Speaker 1>And so we've done so much work on mice in

0:41:25.080 --> 0:41:27.560
<v Speaker 1>the lab. Now that you can just like pop open

0:41:27.600 --> 0:41:30.960
<v Speaker 1>a mouse catalog and you can order mice that like

0:41:31.040 --> 0:41:33.760
<v Speaker 1>have various parts of their immune systems that don't work anymore.

0:41:33.920 --> 0:41:34.160
<v Speaker 5>Wow.

0:41:34.200 --> 0:41:36.520
<v Speaker 1>And so they like ordered some mice that don't have

0:41:36.600 --> 0:41:38.839
<v Speaker 1>T cells, or don't have B cells, or like they're

0:41:38.920 --> 0:41:40.640
<v Speaker 1>lacking various parts of their immune.

0:41:40.320 --> 0:41:43.920
<v Speaker 2>Cells, meaning that there's like an industry that manufactures mice

0:41:44.000 --> 0:41:47.279
<v Speaker 2>with specific deficits that are useful for scientific experiments.

0:41:47.480 --> 0:41:48.760
<v Speaker 5>Yes, yeah, amazing.

0:41:48.800 --> 0:41:51.640
<v Speaker 1>So they essentially ordered some mice who don't have like

0:41:51.760 --> 0:41:54.440
<v Speaker 1>good immune systems in a variety of different ways, and

0:41:54.480 --> 0:41:56.919
<v Speaker 1>they gave them these injections and they still went gray.

0:41:57.280 --> 0:41:59.600
<v Speaker 1>So that was pretty good evidence that it's not something

0:41:59.600 --> 0:42:02.680
<v Speaker 1>about the immune system that's important for creating this gray.

0:42:03.120 --> 0:42:05.920
<v Speaker 1>So the next question they wanted to know was, Okay, well,

0:42:05.960 --> 0:42:09.160
<v Speaker 1>is it something about stress? And usually when you are

0:42:09.200 --> 0:42:14.080
<v Speaker 1>thinking about stress, you think about cortisol or ner adrenaline.

0:42:14.280 --> 0:42:18.920
<v Speaker 1>So cortisol is a hormone that humans make and we

0:42:19.040 --> 0:42:20.960
<v Speaker 1>release it in times of stress. And what it does

0:42:21.000 --> 0:42:23.680
<v Speaker 1>is it helps us like mobilize energy. So for example,

0:42:23.680 --> 0:42:25.880
<v Speaker 1>if you're being chased by a lion, you want to

0:42:25.920 --> 0:42:29.360
<v Speaker 1>make sure you've got as much energy available as you know,

0:42:29.400 --> 0:42:32.400
<v Speaker 1>as many like calories that you could send to your

0:42:32.480 --> 0:42:35.160
<v Speaker 1>muscles or whatever, so that you can run away from

0:42:35.160 --> 0:42:37.359
<v Speaker 1>that lion. It's not going to make you faster than

0:42:37.400 --> 0:42:39.720
<v Speaker 1>you usually would be, but as fast as you're able

0:42:39.760 --> 0:42:41.239
<v Speaker 1>to be. They want to make sure that you can

0:42:41.280 --> 0:42:42.960
<v Speaker 1>be to try to get away from that lion. And

0:42:43.000 --> 0:42:44.839
<v Speaker 1>then after that stress or it tries to help your

0:42:44.840 --> 0:42:47.400
<v Speaker 1>body like recover from this massively horrible thing that just

0:42:47.400 --> 0:42:50.040
<v Speaker 1>happened to you. And so for us, that hormone is

0:42:50.080 --> 0:42:54.520
<v Speaker 1>called cortisol. Mice have a closely related version called cordiicosterone,

0:42:55.560 --> 0:42:59.919
<v Speaker 1>and so they wondered, Okay, maybe it's something about cordicosterone

0:43:00.200 --> 0:43:02.600
<v Speaker 1>that causes graying. And so it turns out that the

0:43:02.800 --> 0:43:07.920
<v Speaker 1>melanocyte stem cells have receptors for cortocosterone. And so what

0:43:07.960 --> 0:43:11.840
<v Speaker 1>that means is that these stem cells can bind to qrtoicosterone.

0:43:11.920 --> 0:43:14.120
<v Speaker 1>And what usually happens when a receptor binds to a

0:43:14.160 --> 0:43:17.400
<v Speaker 1>hormone is that that hormone is sending some message to

0:43:17.440 --> 0:43:19.560
<v Speaker 1>the inside of the cell that the cell needs to

0:43:19.600 --> 0:43:22.520
<v Speaker 1>do something. And usually what that something is is like

0:43:22.880 --> 0:43:26.480
<v Speaker 1>you need to go into your genetic blueprints and start

0:43:26.520 --> 0:43:28.400
<v Speaker 1>making some new compounding.

0:43:28.719 --> 0:43:29.040
<v Speaker 3>Yeah.

0:43:29.080 --> 0:43:33.000
<v Speaker 1>So what they did amazingly is they said, Okay, we're

0:43:33.000 --> 0:43:36.680
<v Speaker 1>going to essentially take the receptors off of the melanocyte

0:43:36.719 --> 0:43:41.120
<v Speaker 1>stem cells, and now we're going to inject the mice

0:43:41.680 --> 0:43:44.719
<v Speaker 1>with the capsais and analog and see what happens. And

0:43:44.760 --> 0:43:48.600
<v Speaker 1>those mice still got gray hairs. So it wasn't about

0:43:48.640 --> 0:43:53.280
<v Speaker 1>the glucocorticoid stress hormones, because even when that hormone can't

0:43:53.360 --> 0:43:56.680
<v Speaker 1>talk to the melanocyte stem cells, you still get gray hairs.

0:43:56.920 --> 0:43:58.640
<v Speaker 3>Are you with me? Because this is kind of confusing,

0:43:58.680 --> 0:44:00.799
<v Speaker 3>but it's beautiful how they're doing this step by step.

0:44:01.000 --> 0:44:04.480
<v Speaker 2>I didn't follow gluco corticoid, but I think I do understand.

0:44:04.840 --> 0:44:08.840
<v Speaker 2>The argument here is that these melanocyte stem cells, the

0:44:08.960 --> 0:44:11.480
<v Speaker 2>things that you need in order to make new melanocytes,

0:44:11.760 --> 0:44:14.520
<v Speaker 2>are disappearing. And they have a button on their outside

0:44:14.560 --> 0:44:18.480
<v Speaker 2>that responds to this stress hormone. But when they disabled

0:44:18.480 --> 0:44:20.719
<v Speaker 2>that button, it didn't change anything. So they don't think

0:44:20.760 --> 0:44:24.680
<v Speaker 2>that pressing that button to distress is killing these melanocytes.

0:44:24.840 --> 0:44:26.400
<v Speaker 3>Thank you, Yes, that's a great way to say it.

0:44:26.400 --> 0:44:30.200
<v Speaker 1>Okay, okay, perfect, And they have another button for nora

0:44:30.239 --> 0:44:34.200
<v Speaker 1>adrenaline and nor adrenaline is just another chemical your body

0:44:34.200 --> 0:44:36.960
<v Speaker 1>makes when you're stressed out, but it comes from different places.

0:44:37.680 --> 0:44:41.480
<v Speaker 1>It can either come from your sympathetic nervous system, so

0:44:41.480 --> 0:44:44.480
<v Speaker 1>it can come from nerves that talk to your hair follicles,

0:44:45.080 --> 0:44:47.560
<v Speaker 1>or it can come from these glands that sit on

0:44:47.600 --> 0:44:50.160
<v Speaker 1>top of your kidneys. They figured out that if you

0:44:50.200 --> 0:44:55.520
<v Speaker 1>remove this button for nor adrenaline, they don't turn gray. Oh,

0:44:55.560 --> 0:44:57.880
<v Speaker 1>and they figured out that the message is not coming

0:44:57.960 --> 0:45:00.480
<v Speaker 1>from on top of the kidneys. The message is coming

0:45:00.520 --> 0:45:03.719
<v Speaker 1>from the nerves. Oh, I'm simplifying a little bit because

0:45:03.719 --> 0:45:05.240
<v Speaker 1>I realized I was getting a little two in the weeds.

0:45:05.239 --> 0:45:06.760
<v Speaker 3>But anyway, it is coming from the nerves.

0:45:06.920 --> 0:45:07.200
<v Speaker 2>Wow.

0:45:07.520 --> 0:45:11.520
<v Speaker 1>And they were actually able to like use this neurotoxin

0:45:12.080 --> 0:45:14.640
<v Speaker 1>to keep the nerves from sending the message to the

0:45:14.640 --> 0:45:18.440
<v Speaker 1>hair follicles and they didn't turn gray when you like

0:45:18.520 --> 0:45:20.680
<v Speaker 1>messed with the nerves. So it's definitely the nerves that

0:45:20.719 --> 0:45:24.200
<v Speaker 1>are sending the message to the melanocytes that is essentially

0:45:24.200 --> 0:45:25.640
<v Speaker 1>making the melanostes disappear.

0:45:25.880 --> 0:45:29.240
<v Speaker 2>And what's the connection then with stress is something about

0:45:29.280 --> 0:45:31.799
<v Speaker 2>the stress that makes the nerves send this message.

0:45:32.000 --> 0:45:36.280
<v Speaker 1>Yeah, so you stress someone out, their sympathetic nervous system,

0:45:36.280 --> 0:45:40.280
<v Speaker 1>their fight or flight system is like, ah, they've released

0:45:40.320 --> 0:45:44.759
<v Speaker 1>nora adrenaline, and that nora adrenaline binds to the melanocyte

0:45:44.800 --> 0:45:47.399
<v Speaker 1>stem cells, so you're the button on the melanocyte stem

0:45:47.480 --> 0:45:50.160
<v Speaker 1>cells has been pushed. But if they are in the

0:45:50.200 --> 0:45:53.400
<v Speaker 1>phase where they're supposed to be sleeping, you've woken them

0:45:53.440 --> 0:45:56.000
<v Speaker 1>up from their sleep and they kind of freak out,

0:45:56.520 --> 0:45:59.600
<v Speaker 1>and instead of I don't know, going back to sleep,

0:46:00.120 --> 0:46:04.640
<v Speaker 1>they start doing something totally unexpected. They all start turning

0:46:04.800 --> 0:46:09.439
<v Speaker 1>into other kinds of cells. I think they're turning into melanocytes,

0:46:10.120 --> 0:46:13.560
<v Speaker 1>and then they migrate away, and so by the time

0:46:13.840 --> 0:46:17.480
<v Speaker 1>this process is done, you don't have any more stem cells.

0:46:17.480 --> 0:46:21.200
<v Speaker 1>They've all done what's called differentiated, which is a fancy

0:46:21.239 --> 0:46:24.040
<v Speaker 1>way of saying they've turned into a final version of

0:46:24.040 --> 0:46:27.120
<v Speaker 1>a cell, and they can't make new like melanocytes anymore.

0:46:27.239 --> 0:46:29.719
<v Speaker 1>And then they migrate away, and so they're not there anymore.

0:46:30.080 --> 0:46:33.240
<v Speaker 1>The next time your hair cycle starts again, they've wandered

0:46:33.239 --> 0:46:37.320
<v Speaker 1>off for reasons we don't understand. And so something about

0:46:37.640 --> 0:46:41.960
<v Speaker 1>freaking out from some stressful event totally like discombobulates your

0:46:42.000 --> 0:46:44.440
<v Speaker 1>melanocyte stem cells and they wander off.

0:46:44.400 --> 0:46:46.799
<v Speaker 2>So that makes sense as a mechanism to explain why

0:46:46.840 --> 0:46:51.000
<v Speaker 2>this happens. But why would melanocytes stem cells have this button.

0:46:51.040 --> 0:46:54.600
<v Speaker 2>Why are they sensitive to the presence of these stress hormones?

0:46:54.719 --> 0:46:55.320
<v Speaker 5>We don't know.

0:46:55.960 --> 0:47:00.680
<v Speaker 1>Ooh yeah, So there has been a connection between pigment

0:47:00.800 --> 0:47:07.680
<v Speaker 1>producing cells like melanocytes and our nervous system for you know,

0:47:07.719 --> 0:47:10.800
<v Speaker 1>like a really long stretch of evolution. So for example,

0:47:11.040 --> 0:47:15.959
<v Speaker 1>octopuses and other cephalopods, if you stress them out, they

0:47:16.080 --> 0:47:19.440
<v Speaker 1>will talk to their pigment producing cells to like change colors,

0:47:19.520 --> 0:47:22.000
<v Speaker 1>kind of like blend in with the environment. But that

0:47:22.040 --> 0:47:24.480
<v Speaker 1>doesn't explain why we have nervous systems that are like

0:47:24.520 --> 0:47:27.759
<v Speaker 1>talking to our melanocytes and our hair follicles. But there

0:47:28.239 --> 0:47:30.799
<v Speaker 1>is this like long connection. Maybe there's some reason why

0:47:30.800 --> 0:47:33.480
<v Speaker 1>it still benefits us that we don't know. But when

0:47:33.480 --> 0:47:35.960
<v Speaker 1>I read the discussion of this paper from twenty twenty,

0:47:35.960 --> 0:47:39.000
<v Speaker 1>they were pretty much like not really clear why this

0:47:39.080 --> 0:47:42.080
<v Speaker 1>is happening, like what the evolutionary benefit would be. Maybe

0:47:42.120 --> 0:47:44.920
<v Speaker 1>it's something that was beneficial millions of years ago and

0:47:44.960 --> 0:47:48.680
<v Speaker 1>there was just never a reason to decouple these connections.

0:47:49.040 --> 0:47:52.120
<v Speaker 2>Maybe it's not so bad for people who have experienced

0:47:52.160 --> 0:47:56.360
<v Speaker 2>stress to advertise that by showing off their gray flowing locks,

0:47:56.360 --> 0:47:58.960
<v Speaker 2>so people know, Oh, you know, Kelly's been through something.

0:47:59.000 --> 0:48:00.000
<v Speaker 2>Let me ask her opinion.

0:48:00.280 --> 0:48:03.880
<v Speaker 1>That's what she's probably wise because she experienced Yes, right,

0:48:03.920 --> 0:48:05.239
<v Speaker 1>grad school gave her gray hair.

0:48:05.320 --> 0:48:10.640
<v Speaker 3>She can tell us to not go No, I had

0:48:10.640 --> 0:48:11.440
<v Speaker 3>fun in grad school.

0:48:11.520 --> 0:48:14.240
<v Speaker 2>And so is this only something that happens in mice

0:48:14.400 --> 0:48:17.040
<v Speaker 2>or is the same mechanism happen in other animals, like

0:48:17.160 --> 0:48:17.640
<v Speaker 2>in people.

0:48:18.040 --> 0:48:20.839
<v Speaker 1>I think it happens in other animals too, Like, I mean,

0:48:21.200 --> 0:48:23.600
<v Speaker 1>dogs definitely go gray. I don't know if they go

0:48:23.680 --> 0:48:25.600
<v Speaker 1>gray for stress, but like, I think, if it's happening

0:48:25.640 --> 0:48:27.600
<v Speaker 1>in mice, it's probably happening in other animals too. So

0:48:27.640 --> 0:48:29.799
<v Speaker 1>I'm guessing this is a pretty common thing.

0:48:30.080 --> 0:48:32.759
<v Speaker 2>And this suggests it might also be a treatment available there.

0:48:32.880 --> 0:48:36.399
<v Speaker 2>You could somehow protect those myocytes so they don't get

0:48:36.400 --> 0:48:37.280
<v Speaker 2>that button pressed.

0:48:37.600 --> 0:48:38.160
<v Speaker 3>Yeah.

0:48:38.200 --> 0:48:40.799
<v Speaker 1>So one, I want to note that it's really refreshing

0:48:40.920 --> 0:48:43.760
<v Speaker 1>to have you be the one mispronouncing a word for once.

0:48:43.880 --> 0:48:46.600
<v Speaker 1>I'm like feeling great about that. And I guess we

0:48:46.880 --> 0:48:48.439
<v Speaker 1>you know, we both give as good as we get

0:48:48.600 --> 0:48:49.120
<v Speaker 1>in terms of.

0:48:49.040 --> 0:48:49.879
<v Speaker 3>Picking on each other.

0:48:50.120 --> 0:48:53.160
<v Speaker 1>But yes, it does suggest that if somebody has had

0:48:53.200 --> 0:48:57.080
<v Speaker 1>like a super stressful experience. Maybe you could try to

0:48:57.520 --> 0:48:59.879
<v Speaker 1>calm them down in some way quickly, in a way

0:48:59.880 --> 0:49:03.520
<v Speaker 1>that might rescue their melanocyte stem cells. You'd have to

0:49:03.560 --> 0:49:05.920
<v Speaker 1>do that pretty fast, because once those stem cells have

0:49:06.000 --> 0:49:07.879
<v Speaker 1>migrated away, they don't come back.

0:49:08.440 --> 0:49:09.680
<v Speaker 3>Yeah, then you've lost them forever.

0:49:09.760 --> 0:49:10.640
<v Speaker 2>Wow, fascinating.

0:49:11.040 --> 0:49:13.160
<v Speaker 1>I really appreciate this question, Joe, because this was, like,

0:49:13.920 --> 0:49:16.359
<v Speaker 1>this was so much fun to read about. Like there

0:49:16.360 --> 0:49:18.160
<v Speaker 1>were lots of things in this paper where I was like,

0:49:18.280 --> 0:49:20.279
<v Speaker 1>I have no idea what you're saying. This is like

0:49:20.640 --> 0:49:23.440
<v Speaker 1>crazy molecular biology stuff, but like, wow, this was a

0:49:23.480 --> 0:49:27.480
<v Speaker 1>cool set of experiments that anyway, I am going to

0:49:27.480 --> 0:49:30.400
<v Speaker 1>try to make sure nothing super stressful happens to hasten

0:49:30.440 --> 0:49:34.680
<v Speaker 1>my decline into silver foxhood, but I'm sure I'll rocket

0:49:34.760 --> 0:49:35.120
<v Speaker 1>either way.

0:49:35.640 --> 0:49:38.120
<v Speaker 2>Well, fortunately it doesn't sound like answering this question was

0:49:38.160 --> 0:49:40.759
<v Speaker 2>that stressful for you, which is a relief. So let's

0:49:40.800 --> 0:49:43.319
<v Speaker 2>send it over to Joe and hear about whether it

0:49:43.360 --> 0:49:45.000
<v Speaker 2>gives him any more gray hairs.

0:49:45.560 --> 0:49:49.239
<v Speaker 7>What a colorful journey to finding that association. I'd like

0:49:49.280 --> 0:49:51.840
<v Speaker 7>to mention that this kind of science, whether search for

0:49:51.880 --> 0:49:55.960
<v Speaker 7>an answer becomes a series of experimental steps, is research

0:49:56.040 --> 0:49:59.080
<v Speaker 7>of the best kind. It's also one everyone can do

0:49:59.160 --> 0:50:01.680
<v Speaker 7>in their own way. Thank you for getting to the

0:50:01.760 --> 0:50:05.520
<v Speaker 7>root of this question without stressing anyone out in the

0:50:05.560 --> 0:50:08.000
<v Speaker 7>same vein as Kelly, I too have a few hairs

0:50:08.040 --> 0:50:11.520
<v Speaker 7>of wisdom. That said, I'm definitely still going for the

0:50:11.560 --> 0:50:15.480
<v Speaker 7>spicy foods. Whether your head is black, blonde, bear, or

0:50:15.520 --> 0:50:18.239
<v Speaker 7>glistening gray, stay show everyone.

0:50:18.239 --> 0:50:21.040
<v Speaker 2>All right. Thank you very much everybody who sent us questions.

0:50:21.080 --> 0:50:23.560
<v Speaker 2>We really do love hearing from you, and one reason

0:50:23.640 --> 0:50:25.920
<v Speaker 2>is that it gives us an excuse to dig into

0:50:25.960 --> 0:50:29.160
<v Speaker 2>some corner of physics or biology that we always wanted

0:50:29.160 --> 0:50:31.200
<v Speaker 2>to understand and never had a reason to spend an

0:50:31.200 --> 0:50:34.359
<v Speaker 2>afternoon on. So thank you very much everybody for being

0:50:34.440 --> 0:50:36.879
<v Speaker 2>curious and for sharing that curiosity with us.

0:50:37.080 --> 0:50:37.440
<v Speaker 5>Thank you.

0:50:44.520 --> 0:50:48.040
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