1 00:00:00,240 --> 00:00:03,040 Speaker 1: Brought to you by the reinvented two thousand twelve Camray. 2 00:00:03,120 --> 00:00:07,480 Speaker 1: It's ready. Are you welcome to stuff you should know 3 00:00:08,080 --> 00:00:16,279 Speaker 1: from house Stuff Works dot Com. Hey, and welcome to 4 00:00:16,320 --> 00:00:20,080 Speaker 1: the podcast. I'm Josh Clark. I can feel pain with 5 00:00:20,120 --> 00:00:22,880 Speaker 1: me as always A Charles W. Chuck Bryant and he 6 00:00:23,440 --> 00:00:29,120 Speaker 1: hold on, dude, Chuck can feel pain as well. I 7 00:00:29,240 --> 00:00:31,560 Speaker 1: just tested him. I wanted to make a hund percent sure. 8 00:00:32,240 --> 00:00:34,040 Speaker 1: That's the second take though, and you didn't really have 9 00:00:34,080 --> 00:00:35,720 Speaker 1: to do it twice. We could effaked it this time. 10 00:00:36,159 --> 00:00:39,280 Speaker 1: I wanted a realistic response. Well that's real, Josh, pinch 11 00:00:39,360 --> 00:00:44,760 Speaker 1: me hurt? Yeah, yeah, you could tell um you are right? Yeah, 12 00:00:44,760 --> 00:00:48,000 Speaker 1: I'm fine. Okay, how you doing besides the throbbing forearm? 13 00:00:48,400 --> 00:00:51,360 Speaker 1: I'm great, sir, and you I'm doing pretty good. Good. 14 00:00:51,560 --> 00:00:56,440 Speaker 1: Everything's just peachy, including with my hair. Josh has a 15 00:00:56,520 --> 00:00:58,240 Speaker 1: he goofed He shaves his head and he kind of 16 00:00:58,240 --> 00:01:01,480 Speaker 1: goofed it so he looks like a a patient from 17 00:01:01,520 --> 00:01:04,280 Speaker 1: some word where he had to surgery or something in 18 00:01:04,280 --> 00:01:08,480 Speaker 1: his on his brain. I didn't goof my hair, that's right. Yeah, 19 00:01:08,760 --> 00:01:13,520 Speaker 1: and I have an eastern black haircut now right. Yeah. Um. 20 00:01:13,560 --> 00:01:15,560 Speaker 1: So other than that I'm feeling pretty good. You're right, 21 00:01:15,560 --> 00:01:19,120 Speaker 1: So you felt emotional pain with your odd haircut. I did, which, 22 00:01:19,120 --> 00:01:22,960 Speaker 1: by the way, Chuck, is different from physical pain. You 23 00:01:23,040 --> 00:01:27,640 Speaker 1: knew that because of a yet to be released audiobook. 24 00:01:28,280 --> 00:01:32,720 Speaker 1: That's right, it's forthcoming. It's a little teaser for everybody. Um, 25 00:01:32,800 --> 00:01:36,119 Speaker 1: But there are actually people out there, Chuck, who cannot 26 00:01:36,400 --> 00:01:42,000 Speaker 1: feel pain straight up, don't feel pain. It's amazing. It 27 00:01:42,160 --> 00:01:46,760 Speaker 1: is very rare, but it happens. It is rare, Chuck. Actually, 28 00:01:46,760 --> 00:01:50,480 Speaker 1: the only hard number that I've seen is UH sixty 29 00:01:50,680 --> 00:01:57,000 Speaker 1: sixty reported cases worldwide, sixties since three. Actually, I've got 30 00:01:57,040 --> 00:01:59,440 Speaker 1: thirty five in the United States as of now. Yeah, 31 00:01:59,480 --> 00:02:01,520 Speaker 1: I've seen I saw that number as well. I've seen 32 00:02:01,560 --> 00:02:05,200 Speaker 1: people who just plumb said, we have no idea how 33 00:02:05,240 --> 00:02:10,519 Speaker 1: many could be under reported, especially with younger kids. UM 34 00:02:10,720 --> 00:02:15,720 Speaker 1: with what we're talking about is called congenital insensitivity to 35 00:02:15,880 --> 00:02:20,120 Speaker 1: pain with an hydrosis. Otherwise, we're just gonna call it 36 00:02:20,160 --> 00:02:23,200 Speaker 1: SIPA for short, right, because that's much easier. And that 37 00:02:23,360 --> 00:02:27,320 Speaker 1: is actually part of a it's a sub type of 38 00:02:27,360 --> 00:02:32,840 Speaker 1: a larger disorder called hereditary sensory and autonomic neuropathy UH. 39 00:02:32,840 --> 00:02:36,079 Speaker 1: And this is actually the type four SIPPA is type 40 00:02:36,080 --> 00:02:39,320 Speaker 1: four s H s A N. Yes, and it's the 41 00:02:39,320 --> 00:02:42,600 Speaker 1: most severe. Uh. Well, we'll get into what it all means, 42 00:02:42,600 --> 00:02:45,120 Speaker 1: but it's the most severe. We will. Um. There's actually 43 00:02:45,320 --> 00:02:48,280 Speaker 1: kind of a recent famous case of it. There's a 44 00:02:48,320 --> 00:02:52,680 Speaker 1: British physician named Dr Jeoffrey Woods. You heard of him, chuck, No, 45 00:02:52,800 --> 00:02:55,799 Speaker 1: But is he one of the g o F guys. Yeah, 46 00:02:55,840 --> 00:02:58,960 Speaker 1: he's British. Yeah, he's spilled programmed with two ms in 47 00:02:59,000 --> 00:03:04,600 Speaker 1: an e UM. But Dr Woods uh travels to Pakistan 48 00:03:04,680 --> 00:03:08,480 Speaker 1: fairly regularly, and while he was there he heard about 49 00:03:08,480 --> 00:03:11,679 Speaker 1: a kid who used to pass like thick needles right 50 00:03:11,680 --> 00:03:15,680 Speaker 1: through his arm walking on hot coals. Uh, and showed 51 00:03:15,720 --> 00:03:18,320 Speaker 1: no signs of feeling pain whatsoever. And he wasn't in 52 00:03:18,360 --> 00:03:22,200 Speaker 1: the gym Rows circus. No, he wasn't, actually, but he 53 00:03:22,520 --> 00:03:25,000 Speaker 1: probably could have done a lot better for himself than 54 00:03:25,080 --> 00:03:28,760 Speaker 1: just on the streets of Lahore right. Um with Dr 55 00:03:28,800 --> 00:03:31,040 Speaker 1: Woods heard about this guy and this little kid and 56 00:03:31,240 --> 00:03:33,880 Speaker 1: was kind of interested and finally got around to trying 57 00:03:33,880 --> 00:03:36,320 Speaker 1: to go see him. Right before he could see him, 58 00:03:36,360 --> 00:03:40,360 Speaker 1: the kid, around his fourteenth birthday died. Actually, Um, he 59 00:03:40,480 --> 00:03:42,840 Speaker 1: was he was. I don't know if he was dared 60 00:03:42,920 --> 00:03:44,440 Speaker 1: or he was doing it for money or whatever, but 61 00:03:44,560 --> 00:03:48,160 Speaker 1: he jumped off a roof and died. But Dr Woods 62 00:03:48,200 --> 00:03:50,320 Speaker 1: got ahold of this kid's family and actually found out 63 00:03:50,360 --> 00:03:55,520 Speaker 1: that a bunch of them have no sensitivity whatsoever to pain. Yeah, 64 00:03:55,600 --> 00:03:59,160 Speaker 1: which is also called analgesia. Oh that's the other word 65 00:03:59,200 --> 00:04:02,240 Speaker 1: for it. Didn't know that. Yeah, pain killers are called analgesics. 66 00:04:02,840 --> 00:04:05,000 Speaker 1: So this would be like the state of not having 67 00:04:05,080 --> 00:04:07,800 Speaker 1: pain or having reduced pain would be analges yet. But 68 00:04:07,880 --> 00:04:10,880 Speaker 1: this isn't just reduced pain as a chuck, No, we're 69 00:04:10,920 --> 00:04:14,480 Speaker 1: talking about no. Uh. You can feel pressure, but you 70 00:04:14,480 --> 00:04:17,000 Speaker 1: can feel no pain. Uh. And you can feel no 71 00:04:17,720 --> 00:04:19,960 Speaker 1: heat or cold. You can feel no temperature on your 72 00:04:19,960 --> 00:04:25,160 Speaker 1: skin either. Right, that's the one with anhydrosis, Yes, exactly. Okay, 73 00:04:25,400 --> 00:04:27,840 Speaker 1: let's talk about the pain part first. Let's talk about 74 00:04:27,839 --> 00:04:31,760 Speaker 1: pain in general. Okay, how do how do we feel pain? Well, Josh, 75 00:04:31,839 --> 00:04:34,440 Speaker 1: your your nervous system is where all this happens. And 76 00:04:34,560 --> 00:04:37,360 Speaker 1: we're talking about your brain here. This is your brain 77 00:04:37,400 --> 00:04:40,560 Speaker 1: on pain. Yeah, your cranial nerves, spinal cord, spinal nerves, 78 00:04:41,240 --> 00:04:45,159 Speaker 1: and other things like your gangli and receptor sensory receptor 79 00:04:45,200 --> 00:04:49,280 Speaker 1: stuff like that, and your nerves carry messages to your 80 00:04:49,279 --> 00:04:51,960 Speaker 1: spine through your body to your spine. Spine carries it 81 00:04:52,000 --> 00:04:55,560 Speaker 1: to your brain and the receptors. If you burn your 82 00:04:55,560 --> 00:04:57,760 Speaker 1: finger or something will send the message up to the 83 00:04:57,800 --> 00:05:00,840 Speaker 1: spine to the brain that says you got burnt, It hurts, right, 84 00:05:00,880 --> 00:05:04,520 Speaker 1: and it sends a response message that moves your hand 85 00:05:04,560 --> 00:05:07,120 Speaker 1: away real quick, touching a hot stove or something like that that. 86 00:05:07,360 --> 00:05:09,520 Speaker 1: You can take it from here though, because your Mr 87 00:05:09,960 --> 00:05:15,920 Speaker 1: Doctor guy Dr Clark, thank you chuck. Um. Actually, the 88 00:05:16,080 --> 00:05:19,400 Speaker 1: sense of pain, the experience of pain is called no susception, 89 00:05:19,520 --> 00:05:23,279 Speaker 1: right um. And this is the experience of physical pain 90 00:05:23,720 --> 00:05:27,400 Speaker 1: as a response to noxious stimuli. And there's actually four 91 00:05:27,440 --> 00:05:31,800 Speaker 1: categories of noxious stimuli. There's mechanical, electrical, thermal, and chemical, 92 00:05:32,320 --> 00:05:37,480 Speaker 1: right um. And we have actually specialized uh nerve endings 93 00:05:37,560 --> 00:05:43,360 Speaker 1: receptors called no susceptors that are responsible just for sending 94 00:05:43,480 --> 00:05:49,920 Speaker 1: pain signals. They use peripheral nerves. Yes. Actually, as as 95 00:05:49,920 --> 00:05:53,000 Speaker 1: painful as pain is, we have it for a reason. 96 00:05:53,720 --> 00:05:55,760 Speaker 1: Like you said, you know you're touching a hot stove 97 00:05:55,839 --> 00:05:57,599 Speaker 1: and your brain says, get your hand off of it, 98 00:05:57,880 --> 00:06:02,120 Speaker 1: right um. We also all uh what one one theory 99 00:06:02,200 --> 00:06:06,120 Speaker 1: of how we develop fear, which is good in and 100 00:06:06,160 --> 00:06:11,680 Speaker 1: of itself as well, UM, is through direct conditioning. That's 101 00:06:11,680 --> 00:06:15,000 Speaker 1: one of three ways we we learn fear responses is 102 00:06:15,000 --> 00:06:18,599 Speaker 1: through direct conditioning. And part of direct conditioning is experiencing 103 00:06:18,640 --> 00:06:21,840 Speaker 1: physical pain because once you've hit the hot stove, once 104 00:06:21,880 --> 00:06:23,920 Speaker 1: you know that the stove is always going to burn 105 00:06:23,960 --> 00:06:27,120 Speaker 1: you exactly, or if you're a dumb kid, maybe two 106 00:06:27,160 --> 00:06:29,160 Speaker 1: or three times, but eventually you're gonna pick it up. 107 00:06:29,360 --> 00:06:34,520 Speaker 1: Right now, what happens with sippa, as far as I understand, um, 108 00:06:34,560 --> 00:06:38,320 Speaker 1: and actually did you notice as well? There's there's not 109 00:06:38,480 --> 00:06:41,400 Speaker 1: a pet explanation of if you have SIPPA, this is 110 00:06:41,440 --> 00:06:43,840 Speaker 1: exactly what happens to you. Yeah, well probably because it's 111 00:06:43,880 --> 00:06:46,520 Speaker 1: so rare. Right. But when you think that if they 112 00:06:46,560 --> 00:06:49,520 Speaker 1: could get this the group of patients together, they would 113 00:06:49,520 --> 00:06:52,359 Speaker 1: find like, okay, well yeah, all of you people are 114 00:06:52,440 --> 00:06:55,960 Speaker 1: lacking no susceptors. Uh So in some patients the no 115 00:06:56,040 --> 00:07:01,640 Speaker 1: susceptors aren't there. In other patients, UM, the peripheral nerves 116 00:07:01,680 --> 00:07:05,960 Speaker 1: that the nose acceptors are attached to, or uses the 117 00:07:06,000 --> 00:07:11,360 Speaker 1: information highway UM aren't there, or else they're not innervated. UM. 118 00:07:11,400 --> 00:07:13,720 Speaker 1: There's a lot of different ways that this this can 119 00:07:13,760 --> 00:07:18,840 Speaker 1: come about. But it all results in this cardinal diagnosis 120 00:07:18,920 --> 00:07:22,400 Speaker 1: or diagnostic tool of SIPPA, which is you feel no 121 00:07:22,480 --> 00:07:27,360 Speaker 1: pain and you aren't responsive to temperature either. But nerve 122 00:07:27,400 --> 00:07:30,640 Speaker 1: conduction is there, right, It depends on some of them. 123 00:07:30,880 --> 00:07:34,840 Speaker 1: There's innervation and others the nerves aren't conducting, they're not 124 00:07:34,880 --> 00:07:40,760 Speaker 1: capable of conducting. And specifically with anhydrosis, I think, um, 125 00:07:40,840 --> 00:07:44,640 Speaker 1: there's no there's no innervation of the nerves in the 126 00:07:44,680 --> 00:07:48,640 Speaker 1: sweat glands. So when you start to get hot, there's 127 00:07:48,680 --> 00:07:51,480 Speaker 1: nothing sending your brain the message, Hey, you're getting hot. 128 00:07:51,520 --> 00:07:54,240 Speaker 1: We need to start sweating so we can cool down. Well, yeah, 129 00:07:54,280 --> 00:07:56,200 Speaker 1: we should go ahead and say that that's the A 130 00:07:56,240 --> 00:08:00,520 Speaker 1: is anhydrosis and after the sip part, and that's the 131 00:08:00,520 --> 00:08:02,960 Speaker 1: most sever your case, and that's when you don't sweat, 132 00:08:03,040 --> 00:08:07,440 Speaker 1: which you know how I sweat. I know you definitely 133 00:08:07,520 --> 00:08:11,120 Speaker 1: don't have anhydrosis. Remember at the aquarium, I sweated underwater 134 00:08:11,400 --> 00:08:13,960 Speaker 1: in like forty degree water too. I mean there was 135 00:08:14,040 --> 00:08:16,440 Speaker 1: like little chunks of ice floating on the surface of 136 00:08:16,480 --> 00:08:19,440 Speaker 1: the water and you had cartoons sweat jumping off your 137 00:08:19,440 --> 00:08:23,120 Speaker 1: forehead did so is I could handle the anhydrosis part 138 00:08:23,200 --> 00:08:25,720 Speaker 1: or at least a slight version of that. I could 139 00:08:25,760 --> 00:08:29,640 Speaker 1: deal with that, right. Uh, and this is our These 140 00:08:29,640 --> 00:08:33,560 Speaker 1: are ekron sweat glands or ekron glands that are responsible 141 00:08:33,640 --> 00:08:37,560 Speaker 1: for regulation of body temperature. So what they they found 142 00:08:37,559 --> 00:08:40,600 Speaker 1: with the anhydrosis, it seems fairly uniform in that respect 143 00:08:41,040 --> 00:08:46,280 Speaker 1: that we the a sip of patients don't have um innervation, 144 00:08:46,600 --> 00:08:51,200 Speaker 1: meaning the nerves aren't becoming activated in their sweat glands. Yeah, 145 00:08:51,200 --> 00:08:53,920 Speaker 1: and that's especially I mean it's bad enough to over 146 00:08:54,080 --> 00:08:56,360 Speaker 1: you know, because you can overheat just as an adult, 147 00:08:56,400 --> 00:09:00,520 Speaker 1: but it's really scary with babies with SIPPA because a 148 00:09:00,559 --> 00:09:04,120 Speaker 1: baby can overheat and die like very easily. Well yeah, actually, 149 00:09:04,160 --> 00:09:11,120 Speaker 1: I think of people who have SIPPA die before or 150 00:09:11,160 --> 00:09:15,440 Speaker 1: by the age of three, and I think another quarter 151 00:09:15,800 --> 00:09:20,679 Speaker 1: of those deaths are um from sepsis from an untreated infection. 152 00:09:21,360 --> 00:09:23,520 Speaker 1: One of the things about not being able to feel 153 00:09:23,559 --> 00:09:26,760 Speaker 1: pain is you can cut yourself and if you're a kid, 154 00:09:27,160 --> 00:09:30,120 Speaker 1: you don't think, well, I'd better treat this cut. And 155 00:09:30,200 --> 00:09:32,880 Speaker 1: at the same time you're not crying, so your parents 156 00:09:32,880 --> 00:09:36,800 Speaker 1: aren't alerted, and so this cut can go untreated become infected. 157 00:09:37,360 --> 00:09:43,840 Speaker 1: When they cut is infected, the bodies immunological response UH 158 00:09:44,160 --> 00:09:47,240 Speaker 1: raises your body temperature. It can lead to a fever, 159 00:09:48,000 --> 00:09:52,040 Speaker 1: and unchecked, this fever can actually lead to um brain damage. 160 00:09:52,520 --> 00:09:54,760 Speaker 1: So a lot of patients with SIPPA who have made 161 00:09:54,760 --> 00:09:57,360 Speaker 1: it past you know, three or so have some form 162 00:09:57,400 --> 00:10:01,400 Speaker 1: of mental retardation. Yeah, they also saw where um. We'll 163 00:10:01,440 --> 00:10:03,240 Speaker 1: get to the tips later, but since you brought it up. 164 00:10:03,280 --> 00:10:06,120 Speaker 1: One of the tips for small kids as they will 165 00:10:06,160 --> 00:10:09,360 Speaker 1: teach the child to recognize blood and teach them what 166 00:10:09,400 --> 00:10:11,760 Speaker 1: that means. So if you see blood, you need to 167 00:10:11,800 --> 00:10:13,640 Speaker 1: come find mommy and daddy real quick because you don't 168 00:10:13,640 --> 00:10:15,920 Speaker 1: know you're hurt. But that's a bad thing to happen, 169 00:10:15,960 --> 00:10:18,200 Speaker 1: So come come find mom and dad. Yeah, and I 170 00:10:18,240 --> 00:10:20,240 Speaker 1: thought these tips that, like you said, we'll get to 171 00:10:20,320 --> 00:10:22,880 Speaker 1: in a minute, or they were pretty clever, right, or 172 00:10:22,920 --> 00:10:27,960 Speaker 1: come fine mom and mom or dad and dad. Chucky guy, 173 00:10:28,720 --> 00:10:30,920 Speaker 1: I've been minded around here. Or just mom or just 174 00:10:31,040 --> 00:10:35,560 Speaker 1: dad or uncle Charlie, who's uh grandma or grandma or 175 00:10:35,640 --> 00:10:40,360 Speaker 1: grandpa and grandpa. There's all kinds of scenarios, A lot 176 00:10:40,360 --> 00:10:43,640 Speaker 1: of know somebody the first person um to be legally 177 00:10:43,679 --> 00:10:48,319 Speaker 1: pronounced a sexual was legally pronounced a sexual in the 178 00:10:48,400 --> 00:10:51,520 Speaker 1: last couple of weeks, I believe. Really, yeah, it's true. 179 00:10:51,720 --> 00:10:58,080 Speaker 1: Very interesting that. Yeah, Okay, where are we, Chuck, Let's 180 00:10:58,120 --> 00:11:02,920 Speaker 1: talk about sipa. The medical history of sippa Okay, as 181 00:11:02,920 --> 00:11:05,280 Speaker 1: far as I could find, it was first described in 182 00:11:05,679 --> 00:11:10,520 Speaker 1: eighteen forty seven, uh and described as what is going 183 00:11:10,559 --> 00:11:13,640 Speaker 1: on here? Yeah, exactly. And actually in the sixties. I 184 00:11:13,720 --> 00:11:16,559 Speaker 1: read an article in nineteen sixty that was based on 185 00:11:17,280 --> 00:11:22,280 Speaker 1: UM a hypothesis that people who feel no pain were 186 00:11:22,320 --> 00:11:26,160 Speaker 1: actually it was actually a psychological disturbance. There's been such 187 00:11:26,200 --> 00:11:29,360 Speaker 1: a massive affront to their ego that as a response, 188 00:11:29,800 --> 00:11:34,280 Speaker 1: the response to their ego mounted resulted in a loss 189 00:11:34,320 --> 00:11:39,640 Speaker 1: of the sensation of pain. That cat just can't feel pain. 190 00:11:39,760 --> 00:11:43,439 Speaker 1: He's so out there, so far out. There is a 191 00:11:43,520 --> 00:11:46,679 Speaker 1: doctor who was who was surveying this literature of UM 192 00:11:46,760 --> 00:11:51,200 Speaker 1: certain patients, and he was describing like how the diagnosis went, 193 00:11:51,360 --> 00:11:53,800 Speaker 1: the diagnosis went. And there's this one poor guy in 194 00:11:53,840 --> 00:11:57,680 Speaker 1: the fifties who he was described as a pretty nice, upbeat, 195 00:11:57,800 --> 00:12:00,439 Speaker 1: bright guy, and he goes to the doctor and it's like, 196 00:12:00,480 --> 00:12:03,079 Speaker 1: I can't feel pain. And the doctors like, oh yeah, 197 00:12:03,360 --> 00:12:05,680 Speaker 1: so you can see this half drunk doctor, right, he's 198 00:12:05,720 --> 00:12:09,360 Speaker 1: got like a glass of scotch and a right and 199 00:12:09,559 --> 00:12:13,719 Speaker 1: uh right, and the little reflective thing on his forehead. Um, 200 00:12:13,760 --> 00:12:17,360 Speaker 1: and he ran this guy through a battery of tests, 201 00:12:17,400 --> 00:12:23,400 Speaker 1: including squeezing his testicles, running an electrical current across his 202 00:12:23,480 --> 00:12:28,439 Speaker 1: lower teeth, and Chuck, it gets worse, taking a skin 203 00:12:28,640 --> 00:12:32,760 Speaker 1: and muscle biopsy without anesthetic. What did he do each 204 00:12:32,800 --> 00:12:35,520 Speaker 1: of these? And was he like what about that? You know? 205 00:12:35,720 --> 00:12:39,080 Speaker 1: I feel that? Can't you imagine like this? Doctors like, oh, yeah, 206 00:12:39,120 --> 00:12:46,920 Speaker 1: that didn't yeah. Um, So the psychological idea was discarded 207 00:12:46,960 --> 00:12:49,880 Speaker 1: pretty quickly. And now, because we're in the age where 208 00:12:49,880 --> 00:12:54,040 Speaker 1: the genome has been cracked, it's all genetics, right, yeah, 209 00:12:54,120 --> 00:12:55,959 Speaker 1: And I guess we should go ahead and mentioned too 210 00:12:56,000 --> 00:12:59,200 Speaker 1: that they think they have narrowed it down to a 211 00:12:59,400 --> 00:13:03,599 Speaker 1: mutation of the t r K A parentheses in t 212 00:13:04,080 --> 00:13:08,079 Speaker 1: r K one gene, which appears to control nerve growth, 213 00:13:08,600 --> 00:13:10,880 Speaker 1: but again they don't know for sure. They just think 214 00:13:10,920 --> 00:13:13,000 Speaker 1: that might be the culprit, right, Chuck, that seems to 215 00:13:13,040 --> 00:13:16,840 Speaker 1: be the likeliest UM candidate, because that gene actually is 216 00:13:17,679 --> 00:13:22,599 Speaker 1: it's responsible for producing nerve growth factor, which goes and 217 00:13:22,760 --> 00:13:27,600 Speaker 1: recruits UM neurons and nerves, isn't I guess it would 218 00:13:27,640 --> 00:13:33,079 Speaker 1: be neurons uh to become no susceptors, and so that 219 00:13:33,160 --> 00:13:36,600 Speaker 1: wouldn't happen, right, right, But they're kind of speculating still 220 00:13:36,600 --> 00:13:38,839 Speaker 1: a little bit, right. Yeah, we still don't have an idea. 221 00:13:38,840 --> 00:13:44,920 Speaker 1: I mean, sixty cases reported worldwide, thirty five in the US. Maybe, although, um, 222 00:13:45,160 --> 00:13:46,960 Speaker 1: it does seem like it would be genetic, like that 223 00:13:47,040 --> 00:13:50,000 Speaker 1: kid in the Little Horror Pakistan when he died and 224 00:13:50,000 --> 00:13:51,840 Speaker 1: the doctor went to go see his family and found 225 00:13:51,840 --> 00:13:55,480 Speaker 1: out he had siblings that had the same condition. Sure, Um, 226 00:13:55,559 --> 00:14:00,960 Speaker 1: that suggests either something environmental close to the home or uh, genetic, 227 00:14:01,280 --> 00:14:04,120 Speaker 1: And that's kind of what they're leaning to. That's the 228 00:14:04,160 --> 00:14:07,200 Speaker 1: genetic part, right, Josh. They do think or do they 229 00:14:07,240 --> 00:14:10,960 Speaker 1: know for sure that it's an autosomal recessive disorder. I 230 00:14:11,000 --> 00:14:12,880 Speaker 1: don't know how they do, but that's that's how I 231 00:14:12,960 --> 00:14:16,400 Speaker 1: take it, right, Which means that both of your parents 232 00:14:16,920 --> 00:14:20,280 Speaker 1: must pass down a copy of this gene. So each 233 00:14:20,280 --> 00:14:23,560 Speaker 1: one of your parents has this mutation and it's not 234 00:14:23,600 --> 00:14:25,480 Speaker 1: related to gender or anything. But they do know that 235 00:14:25,520 --> 00:14:26,880 Speaker 1: both of your parents have to give it to you, 236 00:14:27,720 --> 00:14:31,080 Speaker 1: so that that's probably what makes it rare as well. Well, yeah, 237 00:14:31,360 --> 00:14:34,080 Speaker 1: both of your parents have to have this really rare thing. Apparently, 238 00:14:34,120 --> 00:14:38,480 Speaker 1: also it hasn't It doesn't affect every ethnic group. Oh 239 00:14:38,520 --> 00:14:41,480 Speaker 1: really Yeah, but I was reading another study on this 240 00:14:41,600 --> 00:14:45,560 Speaker 1: from I think two thousand and it was in I 241 00:14:45,640 --> 00:14:48,800 Speaker 1: think Jerusalem or Tel Aviv, one of the two, and 242 00:14:48,840 --> 00:14:52,400 Speaker 1: they got together a bunch of kids who had sippa 243 00:14:52,600 --> 00:14:55,960 Speaker 1: and um, some of them were related, and they took 244 00:14:55,960 --> 00:14:59,440 Speaker 1: a family history and found that I think nine of 245 00:14:59,480 --> 00:15:05,000 Speaker 1: the thirt participants parents were first or second cousins. So 246 00:15:05,040 --> 00:15:07,040 Speaker 1: I wonder how much that has to do with something 247 00:15:07,080 --> 00:15:11,560 Speaker 1: too interesting? Yeah, very interesting? So should we talk about 248 00:15:11,960 --> 00:15:15,320 Speaker 1: some of the problems. I mean, they're pretty obvious, but 249 00:15:15,320 --> 00:15:17,560 Speaker 1: there are something that I didn't actually well, yeah, let's 250 00:15:17,600 --> 00:15:20,040 Speaker 1: talk about raising a baby with sippa. How would you 251 00:15:20,080 --> 00:15:24,160 Speaker 1: first start to recognize that your kid has sippa? Well, 252 00:15:24,680 --> 00:15:27,280 Speaker 1: that's a problem because the first way you would probably 253 00:15:27,320 --> 00:15:31,520 Speaker 1: recognize it is seeing witnessing an accident that should cause 254 00:15:31,640 --> 00:15:34,200 Speaker 1: your baby to cry, and your baby doesn't cry. Right, 255 00:15:34,280 --> 00:15:36,960 Speaker 1: that's like, did you have you ever heard the discovery 256 00:15:37,000 --> 00:15:42,240 Speaker 1: of ether and nitrous ox side is anesthetics right here? Well, 257 00:15:42,280 --> 00:15:44,720 Speaker 1: actually it happened in New York City, but a physician 258 00:15:44,760 --> 00:15:47,800 Speaker 1: from our fair City name ms Dr Crawford Long. Yeah. 259 00:15:47,840 --> 00:15:49,680 Speaker 1: I did a little book report on him when I 260 00:15:49,720 --> 00:15:52,640 Speaker 1: was like the fourth grade. He was like our nineteen 261 00:15:52,720 --> 00:15:55,520 Speaker 1: sixties Scotch and cigarette doctor, and that he liked the 262 00:15:55,560 --> 00:15:59,920 Speaker 1: party and he noticed that people on in the depths 263 00:16:00,080 --> 00:16:03,560 Speaker 1: of an ether bender would run into walls and gash 264 00:16:03,600 --> 00:16:06,920 Speaker 1: their foreheads and not have any response to it whatsoever, 265 00:16:07,160 --> 00:16:11,680 Speaker 1: aside from laughing hysterically. Right exactly, look at all this blood. Yeah, 266 00:16:11,720 --> 00:16:14,520 Speaker 1: so there's there's a similarity there. And well for me 267 00:16:14,560 --> 00:16:17,040 Speaker 1: to add that tangent, we have Crawford Long Hospital here too, 268 00:16:17,080 --> 00:16:19,760 Speaker 1: I know, look at you with the sidebars. So, like 269 00:16:19,800 --> 00:16:21,480 Speaker 1: I said, the first thing it will happen is apparent 270 00:16:21,520 --> 00:16:26,800 Speaker 1: season accident and the child doesn't cry. Um, so you're 271 00:16:26,800 --> 00:16:28,880 Speaker 1: gonna have some problems getting diagnosed. So because it is 272 00:16:28,880 --> 00:16:32,960 Speaker 1: so rare. Uh. And in the meantime, the kid could 273 00:16:33,120 --> 00:16:36,760 Speaker 1: end up with an infection and die of overheating or 274 00:16:36,800 --> 00:16:40,280 Speaker 1: suffer some sort of brain damn. One of the other 275 00:16:40,280 --> 00:16:43,600 Speaker 1: big problems with the baby is um when a baby tease, 276 00:16:44,240 --> 00:16:47,400 Speaker 1: a baby just naws like crazy, but if they don't 277 00:16:47,400 --> 00:16:50,320 Speaker 1: feel pain, they may gnaw like straight through their little 278 00:16:50,360 --> 00:16:52,720 Speaker 1: baby finger without even realizing right, or their tongue or 279 00:16:52,720 --> 00:16:55,000 Speaker 1: their lips. Those are common injuries as well, yeah, which 280 00:16:55,000 --> 00:16:58,040 Speaker 1: is just awful. There's also um ice scratching. Yeah. Well, 281 00:16:58,080 --> 00:16:59,600 Speaker 1: they said though on the teeth, they said that some 282 00:16:59,680 --> 00:17:02,400 Speaker 1: parents it's elect to have the teeth baby teeth removed 283 00:17:02,400 --> 00:17:05,040 Speaker 1: altogether and wait for the adult teeth to come in, 284 00:17:05,080 --> 00:17:07,600 Speaker 1: at which they're in age where they can understand like 285 00:17:07,720 --> 00:17:10,000 Speaker 1: don't bite through your finger. Yeah, but that's not good either, 286 00:17:10,040 --> 00:17:11,840 Speaker 1: because then your child has no teeth and it makes 287 00:17:11,840 --> 00:17:15,240 Speaker 1: it harder to eat and right, but it's like eat 288 00:17:15,600 --> 00:17:18,480 Speaker 1: baby food for many many years, or she right through 289 00:17:18,520 --> 00:17:20,440 Speaker 1: your tongue right right? You know? So what was the 290 00:17:20,480 --> 00:17:22,960 Speaker 1: one you just mentioned? I scratching? Yeah, you know you 291 00:17:23,160 --> 00:17:26,159 Speaker 1: if you are just rubbing your eye or whatever, you 292 00:17:26,320 --> 00:17:30,119 Speaker 1: pretty much know when to stop. If you are a patient, 293 00:17:30,240 --> 00:17:32,760 Speaker 1: a sip of patient, you don't know when to stop. 294 00:17:32,960 --> 00:17:35,640 Speaker 1: I was reading about this five year old girl who 295 00:17:35,680 --> 00:17:40,000 Speaker 1: blinded herself. She can still see shapes, I believe, um. 296 00:17:40,080 --> 00:17:42,960 Speaker 1: But she had one eye removed and scratched the other 297 00:17:43,000 --> 00:17:45,560 Speaker 1: eye and she was five and could barely see. She'd 298 00:17:45,560 --> 00:17:48,320 Speaker 1: done it to herself. Well, another tips, since we're there, 299 00:17:48,640 --> 00:17:52,080 Speaker 1: a lot of parents elect to have little baby goggles 300 00:17:52,320 --> 00:17:53,920 Speaker 1: for their for their child, so they can't get to 301 00:17:53,960 --> 00:17:59,479 Speaker 1: their eyes, which is sad. Yeah, um, hunger pains. This 302 00:17:59,560 --> 00:18:03,320 Speaker 1: was interesting. They don't feel hunger pains, so eating isn't 303 00:18:03,359 --> 00:18:07,879 Speaker 1: something they realized they should do. So uh they sometimes 304 00:18:08,160 --> 00:18:10,880 Speaker 1: sip A patients will set a clock to remind them 305 00:18:10,920 --> 00:18:14,760 Speaker 1: to eat or to use the potty. Right, Because one 306 00:18:14,800 --> 00:18:17,439 Speaker 1: of the ways that you know that you have to 307 00:18:17,520 --> 00:18:20,800 Speaker 1: go number one or go number two is from the 308 00:18:20,840 --> 00:18:24,800 Speaker 1: discomfort involved. Your body is alerted like you need to 309 00:18:24,840 --> 00:18:28,679 Speaker 1: evacuate your bowels, and so you go evacuate your bowels. 310 00:18:28,800 --> 00:18:33,440 Speaker 1: But if you don't have any sense of discomfort whatsoever, Um, 311 00:18:33,720 --> 00:18:35,679 Speaker 1: you aren't going to go to the bathroom. You can 312 00:18:35,760 --> 00:18:41,680 Speaker 1: suffer constipation all manner of horrible results from that from 313 00:18:41,680 --> 00:18:45,359 Speaker 1: holding it too long. Yeah for sure, Um, fractures are 314 00:18:45,400 --> 00:18:48,479 Speaker 1: very common. Obviously. You can slam your hand in the door, 315 00:18:48,600 --> 00:18:50,760 Speaker 1: won't feel the pain, won't realize you've got a broken 316 00:18:50,800 --> 00:18:53,480 Speaker 1: hand and joints to This is something I hadn't thought 317 00:18:53,520 --> 00:18:56,879 Speaker 1: of either. But consider this, like, how many times have 318 00:18:57,160 --> 00:19:00,480 Speaker 1: either one of us moved in our chairs during this podcast? 319 00:19:00,880 --> 00:19:04,479 Speaker 1: And the reason we're moving shifting is because it's become 320 00:19:04,600 --> 00:19:07,840 Speaker 1: uncomfortable to lean on that joint, so we move and 321 00:19:07,880 --> 00:19:10,440 Speaker 1: put the our weight on another joint. That's your body 322 00:19:10,480 --> 00:19:12,719 Speaker 1: telling you to to shift, so you're not putting too 323 00:19:12,800 --> 00:19:16,080 Speaker 1: much stress on anything. Right. If you don't shift, then 324 00:19:16,640 --> 00:19:18,679 Speaker 1: all of that weight is on that joint, and this 325 00:19:18,760 --> 00:19:22,800 Speaker 1: can actually result in charcot joints. These are joints where 326 00:19:22,840 --> 00:19:27,080 Speaker 1: basically you can't feel pain. Uh, to develop charcot joints 327 00:19:27,080 --> 00:19:32,160 Speaker 1: because when you it's the result of like a prolonged 328 00:19:32,200 --> 00:19:37,240 Speaker 1: and repeated destruction of a joint or several joints, And 329 00:19:37,240 --> 00:19:40,320 Speaker 1: what happens is like little bone fragments break off and 330 00:19:40,359 --> 00:19:43,439 Speaker 1: then you have bone pieces grading in the joint, it 331 00:19:43,480 --> 00:19:47,159 Speaker 1: fills with fluid and UH, there's definitely a point of 332 00:19:47,160 --> 00:19:52,679 Speaker 1: no return that can lead to amputation, um limb replacement, 333 00:19:52,760 --> 00:19:55,720 Speaker 1: that kind of stuff. Gez, Well, one of the since 334 00:19:55,720 --> 00:19:58,679 Speaker 1: we're kind of doing the problem tip thing, one of 335 00:19:58,680 --> 00:20:01,399 Speaker 1: the tips don't think we have so far. One of 336 00:20:01,400 --> 00:20:05,080 Speaker 1: the things that they recommend is occupational therapy, so they 337 00:20:05,080 --> 00:20:08,320 Speaker 1: can teach your child different ways to sit and do 338 00:20:08,400 --> 00:20:10,840 Speaker 1: physical tasks to like put the least amount of stress 339 00:20:10,840 --> 00:20:13,800 Speaker 1: possible on those joints, right or they may say your 340 00:20:13,840 --> 00:20:15,680 Speaker 1: kid needs to be in a wheelchair a little more 341 00:20:15,720 --> 00:20:19,400 Speaker 1: than than here. She is true and again very sad. 342 00:20:19,440 --> 00:20:22,040 Speaker 1: This whole thing is just one of the most depressing 343 00:20:22,720 --> 00:20:26,159 Speaker 1: rare disorders I can think of. Uh, if you have 344 00:20:26,200 --> 00:20:30,399 Speaker 1: a baby that has um SIPA, you should probably do 345 00:20:30,600 --> 00:20:34,080 Speaker 1: a regular check over your child, like you need a 346 00:20:34,080 --> 00:20:36,280 Speaker 1: baby proof the heck out of your house. Like it's 347 00:20:36,320 --> 00:20:38,840 Speaker 1: baby proof anyway, but you really need to go overboard 348 00:20:38,880 --> 00:20:42,159 Speaker 1: with softening corners and things like that, making sure the 349 00:20:42,200 --> 00:20:45,359 Speaker 1: stove and anything dangerous isn't accessible the knife drawer, that 350 00:20:45,440 --> 00:20:48,360 Speaker 1: kind of thing. But um, you should also check your 351 00:20:48,520 --> 00:20:50,520 Speaker 1: check your child for until they're old enough to do 352 00:20:50,560 --> 00:20:53,240 Speaker 1: this on their own, check them for injuries, you know, 353 00:20:53,280 --> 00:20:56,160 Speaker 1: a couple of three times a day. Also, um, because 354 00:20:56,200 --> 00:20:59,320 Speaker 1: of the anhydrosis. Uh that a lot of families opt 355 00:20:59,400 --> 00:21:03,320 Speaker 1: to move to cooler climates just you know, to protect 356 00:21:03,320 --> 00:21:07,280 Speaker 1: against overheating. Yeah, and um, Katie Lambert wrote this article 357 00:21:07,600 --> 00:21:11,000 Speaker 1: of stuff you miss in history class are cohorts And 358 00:21:11,119 --> 00:21:16,040 Speaker 1: uh Katie supposed that as far as getting exercise, which 359 00:21:16,200 --> 00:21:18,520 Speaker 1: you know everyone needs, that swimming might be a good 360 00:21:19,160 --> 00:21:20,399 Speaker 1: good thing for them to do. And that kind of 361 00:21:20,400 --> 00:21:23,199 Speaker 1: made sense to me. Yeah, but have you ever like 362 00:21:23,359 --> 00:21:27,760 Speaker 1: swam and sweat it underwater? Well you know it? Well, yeah, 363 00:21:27,920 --> 00:21:30,440 Speaker 1: but now I I wondered about that because I mean, 364 00:21:30,440 --> 00:21:33,680 Speaker 1: if you think about it, if you are sweating underwater, 365 00:21:33,760 --> 00:21:36,560 Speaker 1: then your body's saying you need to be cooler than 366 00:21:36,640 --> 00:21:40,920 Speaker 1: the ambient water temperature. So it could still lead to trouble. 367 00:21:41,200 --> 00:21:44,399 Speaker 1: I guess getting cool water and maybe don't swim so 368 00:21:44,480 --> 00:21:47,000 Speaker 1: much that you're gonna be sweating could be my advice. 369 00:21:47,480 --> 00:21:50,639 Speaker 1: Dr Chuck's advice. That's good advice, Dr Chuck. Although the 370 00:21:50,640 --> 00:21:54,400 Speaker 1: water is a good medium because it's easier on the joints. Yeah, well, 371 00:21:54,400 --> 00:21:56,920 Speaker 1: I think that's why she recommended it. Sure, Uh, there 372 00:21:57,000 --> 00:22:01,399 Speaker 1: is no cure, no that that has happened yet, and 373 00:22:01,440 --> 00:22:03,760 Speaker 1: it's so rare that it's it's one of these things 374 00:22:03,800 --> 00:22:05,840 Speaker 1: it's hard to get a cure when you don't have 375 00:22:06,680 --> 00:22:09,560 Speaker 1: anyone to test it on. Yeah, although Chuck, don't you 376 00:22:09,600 --> 00:22:13,760 Speaker 1: think the advent of stem cells will probably cure everything? 377 00:22:14,880 --> 00:22:17,199 Speaker 1: I hope so. Well, I mean think about it, it's 378 00:22:17,240 --> 00:22:20,240 Speaker 1: a if it's a genetic flaw measually that means that 379 00:22:20,280 --> 00:22:23,560 Speaker 1: an enzyme or protein isn't being produced, so you just 380 00:22:23,920 --> 00:22:27,399 Speaker 1: use stem cells to generate that enzyme or protein and 381 00:22:29,160 --> 00:22:32,159 Speaker 1: R Clark no more sippa. There are a couple of 382 00:22:32,200 --> 00:22:35,399 Speaker 1: websites should we go ahead and plug those. Gift of 383 00:22:35,440 --> 00:22:38,560 Speaker 1: Pain is a website set up by a family whose 384 00:22:38,640 --> 00:22:41,600 Speaker 1: daughter has SIPPA, and if you want to have your 385 00:22:41,640 --> 00:22:43,320 Speaker 1: heart broken and learn a little bit, you can go 386 00:22:43,440 --> 00:22:46,680 Speaker 1: visit there and help. Roberto dot com is another one 387 00:22:47,119 --> 00:22:51,520 Speaker 1: that details a young boy with SIPPA and Chuck. Also 388 00:22:51,680 --> 00:22:55,240 Speaker 1: there is, from what I understand um, a pretty good 389 00:22:55,240 --> 00:22:59,960 Speaker 1: documentary called A Life Without Pain by director Melody Guild 390 00:23:00,280 --> 00:23:04,400 Speaker 1: and it's about SIPPA. Huh, it's supposed to be pretty cool. 391 00:23:04,440 --> 00:23:07,639 Speaker 1: I haven't seen it, but anybody interested, we want to 392 00:23:07,720 --> 00:23:14,560 Speaker 1: rent that? And I say look for a pain podcast 393 00:23:14,600 --> 00:23:16,320 Speaker 1: in the future. I think we should do one on 394 00:23:16,400 --> 00:23:18,720 Speaker 1: pain Josh and Chuck's House of Pain. Do you know 395 00:23:18,760 --> 00:23:20,680 Speaker 1: how many times I'm gonna pinch you during that thing? 396 00:23:21,520 --> 00:23:23,800 Speaker 1: It's gonna be rough, hopefully no more than once. It 397 00:23:23,840 --> 00:23:26,240 Speaker 1: will be more than once, all right. If you want 398 00:23:26,280 --> 00:23:28,800 Speaker 1: to learn more about SIPPA, type in c I p 399 00:23:29,040 --> 00:23:31,080 Speaker 1: A in the handy search bar at how Stuff works 400 00:23:31,160 --> 00:23:42,359 Speaker 1: dot com. That means it's time for listener mayle yes sir, exactly, Chuck, 401 00:23:42,560 --> 00:23:46,119 Speaker 1: I want us to give a special shout out the 402 00:23:46,280 --> 00:23:52,000 Speaker 1: three sisters triplets. In fact, we have triplets triplet listeners. Yeah, Helen, 403 00:23:52,160 --> 00:23:56,840 Speaker 1: Spence and Echo, and they all three are voracious stuff. 404 00:23:56,880 --> 00:24:00,399 Speaker 1: You should know listeners A cool name, Yeah, yeah, I 405 00:24:00,480 --> 00:24:03,720 Speaker 1: like it. A Spence goes by Zebra apparently just came 406 00:24:03,720 --> 00:24:05,960 Speaker 1: in when I was on vacation. Huh yeah, yeah, because 407 00:24:05,960 --> 00:24:08,719 Speaker 1: you replied I did, and you promised the shout out 408 00:24:08,760 --> 00:24:11,879 Speaker 1: and never gave it. Yeah. They we didn't do a 409 00:24:11,920 --> 00:24:14,280 Speaker 1: shout out and we are now though, I mean, come on, 410 00:24:14,840 --> 00:24:16,920 Speaker 1: they break me over the coals and I responded, yeah, 411 00:24:16,920 --> 00:24:18,879 Speaker 1: And you know, we typically don't do shoutouts because we 412 00:24:18,920 --> 00:24:21,640 Speaker 1: get request and there's just too many of them. Yeah, 413 00:24:21,640 --> 00:24:23,720 Speaker 1: but how many triplets do we have listening to? Exactly? 414 00:24:23,800 --> 00:24:26,479 Speaker 1: So if it's something remarkable, or if you want your 415 00:24:26,520 --> 00:24:29,520 Speaker 1: name read so bad, just tell us your quadruplets and 416 00:24:29,520 --> 00:24:32,600 Speaker 1: make up three names. So you guys keep the fourth 417 00:24:32,640 --> 00:24:36,600 Speaker 1: doubt and thanks for listening. Thank you girls, and we'll 418 00:24:36,600 --> 00:24:39,760 Speaker 1: get the listener mail eventually, I think. But we should 419 00:24:39,800 --> 00:24:43,960 Speaker 1: probably plug Facebook and Twitter tweet tweet. We are children 420 00:24:44,080 --> 00:24:49,919 Speaker 1: of the next generation. I don't know modern why I 421 00:24:49,960 --> 00:24:54,359 Speaker 1: think no your x M. Why no, seriously, we're definitely 422 00:24:54,400 --> 00:24:58,320 Speaker 1: not millennial. So, yes, we're on Facebook now, for sure. 423 00:24:58,760 --> 00:25:01,399 Speaker 1: We're on Facebook. We have can validated are We had 424 00:25:01,480 --> 00:25:03,159 Speaker 1: multiple pages. It was kind of a mess, but now 425 00:25:03,200 --> 00:25:07,159 Speaker 1: we're all consolidated. We're personally putting stuff on Facebook and 426 00:25:07,200 --> 00:25:09,320 Speaker 1: talking to people. It's kind of kind of fun. Actually, yeah, 427 00:25:09,400 --> 00:25:11,280 Speaker 1: it is. You're doing a heck of a job, Chuck. 428 00:25:11,960 --> 00:25:15,400 Speaker 1: You you can type in stuff you should know on 429 00:25:15,480 --> 00:25:18,720 Speaker 1: Facebook's handy search bar and that should bring up our page. 430 00:25:18,760 --> 00:25:21,000 Speaker 1: You go ahead and join. I'm very curious to see 431 00:25:21,000 --> 00:25:23,600 Speaker 1: how many people join. Yeah, you know, as long as 432 00:25:23,640 --> 00:25:25,480 Speaker 1: we have more than all the other podcasts combined, and 433 00:25:25,640 --> 00:25:29,000 Speaker 1: I'm fine. Yeah. And the same goes for Twitter too. 434 00:25:29,040 --> 00:25:32,960 Speaker 1: Do you have that same that same desire, the same goal. Yeah, 435 00:25:33,040 --> 00:25:36,360 Speaker 1: so I've embraced Twitter. I can't believe it. Yeah, I'm tweeting. Yeah, 436 00:25:36,520 --> 00:25:40,359 Speaker 1: Chuck's first tweet was hilarious, as I imagine all successive 437 00:25:40,359 --> 00:25:44,320 Speaker 1: tweets will be. Our Twitter name is s y s 438 00:25:44,400 --> 00:25:49,600 Speaker 1: K podcast. That's our Twitter name at yeah past right, 439 00:25:49,640 --> 00:25:52,720 Speaker 1: the little at simbulture for those of you who don't 440 00:25:52,720 --> 00:25:55,680 Speaker 1: know how that works. Right, Uh, so you can check 441 00:25:55,720 --> 00:25:59,240 Speaker 1: those out join up, follow us, and we will be interacting. Right, 442 00:25:59,440 --> 00:26:02,480 Speaker 1: We're gonna come down from our ivory tower, right, yeah, 443 00:26:02,600 --> 00:26:06,520 Speaker 1: all right? Uh so, Josh, I'm gonna call this um 444 00:26:06,520 --> 00:26:10,840 Speaker 1: earthquake survivor. Did you read this one? Pretty remarkable? You're 445 00:26:10,880 --> 00:26:13,760 Speaker 1: You're back. You're not on vacation anymore. Hey, Josh and Chuck. 446 00:26:13,800 --> 00:26:16,639 Speaker 1: I just wanted to email and say thanks for unknowingly 447 00:26:16,760 --> 00:26:19,159 Speaker 1: doing a lot to keep things normal for me in 448 00:26:19,200 --> 00:26:22,320 Speaker 1: the least normal of times. Let me explain. I live 449 00:26:22,359 --> 00:26:25,880 Speaker 1: in Santiago, Chile, and in late February I was invited 450 00:26:25,920 --> 00:26:31,040 Speaker 1: to the camping trip in a place down south called Mocha. 451 00:26:32,359 --> 00:26:36,800 Speaker 1: Do you like my phonetic pronunciations. It was all really 452 00:26:36,880 --> 00:26:39,040 Speaker 1: last minute, but before leaving I managed to grab ahold 453 00:26:39,040 --> 00:26:41,720 Speaker 1: of your latest podcast, which was How Braille Works, put 454 00:26:41,760 --> 00:26:44,080 Speaker 1: it on the old iPod. I thought I might need 455 00:26:44,080 --> 00:26:46,879 Speaker 1: it for the long bus ride, and I only grabbed 456 00:26:46,880 --> 00:26:48,919 Speaker 1: that one because, being a true fan, I had already 457 00:26:48,920 --> 00:26:53,600 Speaker 1: listened to the others, So good for you, Ignacio. On 458 00:26:53,600 --> 00:26:55,919 Speaker 1: our second night camping on the island, we had an 459 00:26:55,960 --> 00:27:00,199 Speaker 1: eight point eight Richter earthquake, if you remember, and we 460 00:27:00,200 --> 00:27:03,600 Speaker 1: were pretty near the epicenter. We had to run from 461 00:27:03,640 --> 00:27:07,080 Speaker 1: a tsunami, which only gave us about seven minutes to 462 00:27:07,119 --> 00:27:10,280 Speaker 1: get the higher ground. After the earthquake, our tents and 463 00:27:10,359 --> 00:27:12,800 Speaker 1: all of our stuff was washed away. We never saw 464 00:27:12,800 --> 00:27:15,600 Speaker 1: it again. Turned out we had it easy. Most of 465 00:27:15,640 --> 00:27:17,440 Speaker 1: the homes on the island were taken by the wave, 466 00:27:18,359 --> 00:27:21,600 Speaker 1: and we camped without tents of course, with the locals 467 00:27:21,680 --> 00:27:24,399 Speaker 1: up on a hill for a couple of days before 468 00:27:24,440 --> 00:27:26,520 Speaker 1: being able to even take a plane to start our 469 00:27:26,560 --> 00:27:29,600 Speaker 1: journey back home, which was difficult, Josh, because the bridges 470 00:27:29,600 --> 00:27:31,879 Speaker 1: were down, streets were cracked, and there was no gas 471 00:27:31,960 --> 00:27:34,280 Speaker 1: at the gas stations, that kind of thing for like 472 00:27:34,359 --> 00:27:36,919 Speaker 1: five days. Um. In the middle of it all, I 473 00:27:36,960 --> 00:27:40,159 Speaker 1: was feeling really bad about everything, though grateful for being alive, 474 00:27:40,800 --> 00:27:42,840 Speaker 1: and I was not really knowing about my friends or 475 00:27:42,840 --> 00:27:45,520 Speaker 1: family since cell phones were down and I was in 476 00:27:45,560 --> 00:27:47,920 Speaker 1: the middle of the least normal situation I'd ever been. 477 00:27:48,400 --> 00:27:51,480 Speaker 1: Then I remembered I had your podcast, pulled out my 478 00:27:51,520 --> 00:27:54,480 Speaker 1: iPod which I had saved in my Fannie pack and 479 00:27:54,520 --> 00:27:58,320 Speaker 1: just listen with my eyes closed, really happy because that was, 480 00:27:58,359 --> 00:28:01,360 Speaker 1: for the first time the only nection to normal I had. 481 00:28:01,760 --> 00:28:05,280 Speaker 1: That is awesome, really cool. Uh. It made the hugest difference. 482 00:28:05,320 --> 00:28:07,320 Speaker 1: So I wanted to say thank you so much like 483 00:28:07,359 --> 00:28:09,159 Speaker 1: you guys to stop and think what a difference you 484 00:28:09,200 --> 00:28:12,600 Speaker 1: can make in the listeners lives. So let's stop and 485 00:28:12,640 --> 00:28:17,399 Speaker 1: think for a moment. All right, all right, nice? I 486 00:28:17,400 --> 00:28:20,840 Speaker 1: feel good. How often do we just sit and be quiet? Never? 487 00:28:21,080 --> 00:28:25,639 Speaker 1: Never what we're supposed to do? Uh? You you have 488 00:28:25,680 --> 00:28:28,680 Speaker 1: a loyal listener for years to come. That is from Ignatio. Thanks. 489 00:28:28,720 --> 00:28:31,640 Speaker 1: Ignatio was alive and well thank god. Did you hear 490 00:28:31,680 --> 00:28:36,360 Speaker 1: about the Day's Army Family or the Day's Arms. They're 491 00:28:36,440 --> 00:28:39,680 Speaker 1: a family from Haiti who survived the Porter Prince quake 492 00:28:40,200 --> 00:28:42,960 Speaker 1: and they had a son who lived in Saniago who's like, 493 00:28:43,000 --> 00:28:45,720 Speaker 1: come live with me. You're kidding. They moved to Saniago 494 00:28:45,880 --> 00:28:50,480 Speaker 1: just in time to survive the Chili quake, survived both though. Yeah, yeah, 495 00:28:50,800 --> 00:28:53,200 Speaker 1: and since you said that that way, it's the name. 496 00:28:53,280 --> 00:28:56,000 Speaker 1: What did you say? The name of the place was Saniago. 497 00:28:57,760 --> 00:29:00,920 Speaker 1: The Day's Arms, Yeah, they're the family. That's that's the 498 00:29:01,080 --> 00:29:05,160 Speaker 1: plane Illinois. We should say, well we goofed that one. 499 00:29:05,440 --> 00:29:09,920 Speaker 1: We didn't know. It's apparently planes death planes. Dutch Boot 500 00:29:10,160 --> 00:29:12,160 Speaker 1: sounds very strange because it would seem like it would 501 00:29:12,160 --> 00:29:15,280 Speaker 1: be silent, but everyone made fun of me saying you 502 00:29:15,360 --> 00:29:20,360 Speaker 1: sounded like tattoo with the plane deplane. I think we're 503 00:29:20,400 --> 00:29:23,640 Speaker 1: the same. We're interchangeable. My pain is your pain. You 504 00:29:23,680 --> 00:29:29,000 Speaker 1: can you can switch our guts, right bellies. So officially, UH, 505 00:29:29,240 --> 00:29:31,160 Speaker 1: I would like to switch bellies. You're a slightly smaller 506 00:29:31,200 --> 00:29:33,719 Speaker 1: than mine. Thank you. UM. Officially, we'd like to make 507 00:29:33,760 --> 00:29:37,520 Speaker 1: that correction. It is de Planes, Illinois, and it's yo. 508 00:29:37,680 --> 00:29:43,080 Speaker 1: Claire yeo. Claire was continent, it's not. And in Canada 509 00:29:43,280 --> 00:29:48,880 Speaker 1: they called Canadian bacon bacon. Yes, Canadians. We have corrected 510 00:29:48,880 --> 00:29:51,840 Speaker 1: that for two years now, so you can stop with 511 00:29:51,880 --> 00:29:56,000 Speaker 1: the emails. It's a joke. If you have a correction 512 00:29:56,040 --> 00:29:58,280 Speaker 1: you want to send Chuck or me, or you want 513 00:29:58,320 --> 00:30:02,800 Speaker 1: to get into some UH email combat over a topic 514 00:30:02,880 --> 00:30:05,440 Speaker 1: and issue something like that, send us an email. Do 515 00:30:05,600 --> 00:30:10,040 Speaker 1: not cite Wikipedia UH to support your claims, or else 516 00:30:10,080 --> 00:30:13,360 Speaker 1: you've lost right out of the gate. Do better wrap 517 00:30:13,400 --> 00:30:18,360 Speaker 1: it up. Send it to stuff podcast at how stuff 518 00:30:18,360 --> 00:30:25,000 Speaker 1: works dot com for more on this and thousands of 519 00:30:25,000 --> 00:30:28,360 Speaker 1: other topics. Is that how stuff works dot com. Want 520 00:30:28,400 --> 00:30:31,040 Speaker 1: more how stuff works, check out our blogs on the 521 00:30:31,080 --> 00:30:36,320 Speaker 1: house stuff works dot com home page. Brought to you 522 00:30:36,360 --> 00:30:39,720 Speaker 1: by the reinvented two thousand twelve camera. It's ready, are 523 00:30:39,760 --> 00:30:39,960 Speaker 1: you