WEBVTT - Listener Questions #14

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<v Speaker 1>If everything is quantum fields, how do their ripples make

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<v Speaker 1>banana peels?

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<v Speaker 2>What's the mutation rate for the common cold? Does the

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<v Speaker 2>virus change moving through my household?

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<v Speaker 1>Is their mass? In pure information? Do I get heavier

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<v Speaker 1>with more education?

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<v Speaker 2>Whatever questions keep you up at night, Daniel and Kelly's

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<v Speaker 2>answers will make it right.

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<v Speaker 1>Welcome to another Listener Questions episode on Daniel and Kelly's

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<v Speaker 1>Extraordinary Universe.

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<v Speaker 2>Hello. I'm Kelly Wienersmith, and I study parasites and space,

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<v Speaker 2>but not parasites in space.

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<v Speaker 3>Not yet, at least that's all right.

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<v Speaker 4>Hi.

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<v Speaker 3>I'm Daniel.

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<v Speaker 1>I'm a particle physicist, and I want to figure out

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<v Speaker 1>the problems of the universe before the aliens come and

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<v Speaker 1>spoil the story by telling.

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<v Speaker 2>Us, oh, interesting, you know. The intro sort of makes

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<v Speaker 2>it sound like maybe this is going to be an

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<v Speaker 2>episode about Bigfoot or something. We both have gotten a

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<v Speaker 2>little bit out there with our intros this morning, but

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<v Speaker 2>we're going to bring it down to Earth, which reminds

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<v Speaker 2>me of an interesting talk that I gave on Earth. Well,

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<v Speaker 2>I don't know if it's interesting. It was my talk,

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<v Speaker 2>the talk that I gave for Western University Space Day

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<v Speaker 2>recently and I was giving my usual City on Mars

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<v Speaker 2>talk and up in the balcony was an entire Girl

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<v Speaker 2>Scout troop boom.

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<v Speaker 1>Do you think they were looking to plan an expedition

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<v Speaker 1>to space?

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<v Speaker 2>I don't know. Girl Scouts can do anything. Many maybe

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<v Speaker 2>they were. Maybe they're planning on taking over the world,

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<v Speaker 2>but they want to know how to take over space too.

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<v Speaker 2>They did bring delicious cookies, so that was great.

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<v Speaker 3>Do they ask good questions?

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<v Speaker 2>That's what I was going to say. They asked the

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<v Speaker 2>greatest questions, so they asked fantastic questions. And I was

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<v Speaker 2>a little bit nervous because I hadn't planned on there

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<v Speaker 2>being kids. So I have a whole section about how

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<v Speaker 2>the process of expanding family size might be indited by

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<v Speaker 2>the space environment. And the first question that I got

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<v Speaker 2>was one of the girls from the Scouts raised her

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<v Speaker 2>hand and said, in your section on reproduction. And I

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<v Speaker 2>immediately was like, oh God, this is not a good start.

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<v Speaker 2>I don't want to give the birds and the bees chat.

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<v Speaker 2>And she said something about the image you used on

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<v Speaker 2>that slide had two adults in spacesuits holding two babies

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<v Speaker 2>in spacesuits. Wouldn't it be expensive to make spacesuits.

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<v Speaker 1>For babies, all right, it's an engineering question.

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<v Speaker 3>Yeah, And I think I.

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<v Speaker 2>Said something like I am so relieved that that's what

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<v Speaker 2>you asked, And then I explained, like, you know, sometimes

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<v Speaker 2>it's hard using arts to explain concepts, because we didn't

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<v Speaker 2>actually mean that people will probably be bringing babies in

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<v Speaker 2>space suits out on the surface because space radiation. You

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<v Speaker 2>probably wouldn't want to expose your baby to that on

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<v Speaker 2>the Martian surface.

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<v Speaker 1>And then you need like constantly new spacesuits as they grow.

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<v Speaker 1>I know, as a parent of children who once grew

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<v Speaker 1>very rapidly, that's very frustrating how quickly they outgrow all

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<v Speaker 1>their stuff.

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<v Speaker 2>Oh my gosh. Yes, but I mean eventually we will

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<v Speaker 2>need different shapes and sizes of space suits for the

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<v Speaker 2>diversity of body types that will be up there. But

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<v Speaker 2>my question for you is, have you ever worked with

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<v Speaker 2>an artist or use some art that didn't at all

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<v Speaker 2>portray what you had intended and you didn't realize it

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<v Speaker 2>would be taken seriously because you just meant it to

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<v Speaker 2>be like a cute, funny image about families in space,

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<v Speaker 2>for example.

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<v Speaker 1>Well, the stuff that I write about usually is pretty

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<v Speaker 1>family friendly, but often it's kind of abstract, and I

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<v Speaker 1>struggle sometimes to describe it accurately with words, and then

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<v Speaker 1>I wonder, like, hmmm, how is my illustrator friend going

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<v Speaker 1>to put this into a picture? Like what visual can

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<v Speaker 1>you use to describe quantum fields and tie this all together?

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<v Speaker 1>But I've been lucky to work with very talented illustrators

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<v Speaker 1>who do a great job of making these exceptional visuals,

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<v Speaker 1>taking the abstract and making a concrete so that the

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<v Speaker 1>reader can understand the concepts.

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<v Speaker 2>To be clear, I think my artist collaborator, slash husband

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<v Speaker 2>does a great job. But I think sometimes you just

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<v Speaker 2>assume that the audience will get that this is just

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<v Speaker 2>like a fun artistic image, as like a palette cleanser

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<v Speaker 2>for the difficult stuff we just told you. But you

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<v Speaker 2>know it doesn't always go over the way that you intended.

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<v Speaker 1>Yeah, well, there's another fine line there, which is sometimes

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<v Speaker 1>you want to make jokes to lighten the mood, right.

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<v Speaker 1>I remember in our first book, we talked about what

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<v Speaker 1>space can do, and I'd written this space can bend,

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<v Speaker 1>it can expand, it can ripple, and Jorge drew a

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<v Speaker 1>hilarious little doodle of space bending and expanding and rippling,

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<v Speaker 1>and then he added a fourth one of like space breakdancing,

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<v Speaker 1>and you always got to wonder like, okay, is that

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<v Speaker 1>ridiculous enough that people get Okay, that's obviously a joke

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<v Speaker 1>to lighten the mood, or somebody out there being like, well,

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<v Speaker 1>I don't know if space can ripple and expand maybe

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<v Speaker 1>it could breakdance.

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<v Speaker 3>What does that mean?

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<v Speaker 1>We are the equations of breakdancing.

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<v Speaker 2>Yep.

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<v Speaker 1>So you always gott to walk that fine line.

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<v Speaker 2>Zach and I have had so many of those conversations

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<v Speaker 2>where he's like, people are going to get it's a joke,

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<v Speaker 2>and I was like, maybe they won't. There are humorless

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<v Speaker 2>people out there who will be confused.

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<v Speaker 1>And sometimes the reality is so ridiculous people might think

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<v Speaker 1>you're making a joke. In our latest book about what

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<v Speaker 1>science Aliens Might do, we talk about how people tried

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<v Speaker 1>to communicate with aliens, and there's a guy who wrote

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<v Speaker 1>letters in the sand and set them on fire hoping

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<v Speaker 1>that Martians would read them. And that sounds like I'm

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<v Speaker 1>made up ridiculous example. So I remember adding a footnote

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<v Speaker 1>being like, I know, we make a ridiculous example sometimes

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<v Speaker 1>for humor. This is not one of those cases.

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<v Speaker 2>Yes, everyone while humans are just so crazy you need

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<v Speaker 2>to be like, no, this isn't a joke. I'm not

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<v Speaker 2>going into fiction here.

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<v Speaker 1>Amazing And if anybody's interested in that book, it's coming

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<v Speaker 1>out in November. It's called Do Aliens Speak Physics? By

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<v Speaker 1>it anywhere you get books, and.

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<v Speaker 2>I read an early copy and I can tell you

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<v Speaker 2>it's amazing.

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<v Speaker 3>And we're gonna be talking about it a lot until

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<v Speaker 3>it comes out.

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<v Speaker 2>Yep. Yeah, nice to have a platform. You know what

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<v Speaker 2>else is awesome?

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<v Speaker 3>What's that?

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<v Speaker 2>Our listeners, they are so awesome and they ask such

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<v Speaker 2>amazing questions. And we've got like a question from kids

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<v Speaker 2>theme going on today, and so let's start with our

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<v Speaker 2>first ques question from Ryan and thirteen year old Grace

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<v Speaker 2>from the best states in these United States.

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<v Speaker 1>I'm confused, they're not from California.

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<v Speaker 3>What are you.

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<v Speaker 2>Talking about, oh, Daniel.

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<v Speaker 1>Despite their coming from Virginia, Let's hear about Grace's question.

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<v Speaker 4>Hey, Daniel and Kelly. My name is Ryan and I

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<v Speaker 4>have my thirteen year old daughter, Grace here with me.

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<v Speaker 4>We live in Virginia, and she came up with an

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<v Speaker 4>interesting question after we discussed your episode on particles and

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<v Speaker 4>the current understanding that they are ripples in fields?

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<v Speaker 5>Hi, this is Grace, and here's my question. I don't

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<v Speaker 5>understand how ripples make things. For instance, how do a

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<v Speaker 5>bunch of ripples in a field somehow all add up

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<v Speaker 5>to make a person or banana or sloth? Thanks for

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<v Speaker 5>taking my question. We love the podcast all.

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<v Speaker 2>Right, Daniel, As someone who is a huge fan of sloths,

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<v Speaker 2>I now desperately want to understand how ripples help make

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<v Speaker 2>up a sloth.

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<v Speaker 1>I love this question because this is the whole point

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<v Speaker 1>of physics, to take our everyday experience and explain it

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<v Speaker 1>in terms of the microscopic stuff that's happening. To like

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<v Speaker 1>pull back the veil and say what's really going on underneath?

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<v Speaker 1>And it's cool to say, oh, what's going on underneath?

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<v Speaker 1>Is this complicated thing with fields and particles and waves

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<v Speaker 1>and whatever. But Grace is exactly right that the second

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<v Speaker 1>part of that is to weave it together so that

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<v Speaker 1>it does explain our everyday experience. You've got to give

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<v Speaker 1>a path sort of like an intellectual ladder, from the

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<v Speaker 1>microscopic explanation back to the macroscopic to show how they

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<v Speaker 1>come together. So thank you Grace for asking this question.

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<v Speaker 2>It's a fantastic question, and I love that both banana's

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<v Speaker 2>and sloughts got featured exactly because what good is physics

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<v Speaker 2>if it's not explaining biology.

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<v Speaker 1>And maybe there's a banana sloth out there, oh that

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<v Speaker 1>we could explain.

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<v Speaker 2>One day, delicious and easy to catch.

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<v Speaker 3>Probably why they went extinct.

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<v Speaker 1>So let's get to particles and ripples and quantum fields

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<v Speaker 1>and all that. Grace's question is how ripples make things.

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<v Speaker 1>So let's zoom all the way back down to ripples,

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<v Speaker 1>and then let's walk our way back up to the

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<v Speaker 1>macroscopics to the sloth in the banana. So like one

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<v Speaker 1>hundred years ago, we were trying to understand what stuff

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<v Speaker 1>is made out of. We started taking stuff apart, and

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<v Speaker 1>we realized it's made out of elements, and those elements

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<v Speaker 1>are made out of atoms, and eventually we had little

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<v Speaker 1>particles protons and neutrons and electrons, and back then, I

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<v Speaker 1>think people were still thinking that those were little bits

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<v Speaker 1>of stuff that you could like pack together like legos

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<v Speaker 1>to make bigger stuff that was the sort of microscopic

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<v Speaker 1>to macroscopic, Like the legos were super duper tiny, almost

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<v Speaker 1>incomprehensibly tiny, and there were so many of them. You know,

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<v Speaker 1>Avogado's number is a big number. But if you click

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<v Speaker 1>them all together, you made macroscopic stuff. And that was

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<v Speaker 1>our understanding, right.

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<v Speaker 2>And on the plus side, you can step on them

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<v Speaker 2>and it doesn't hurt.

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<v Speaker 3>The a particle legos.

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<v Speaker 1>Yes, But then we learned, oh, they're not really little

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<v Speaker 1>bits of stuff. Actually, they're like waves. And quantum mechanics

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<v Speaker 1>came around and told us that they don't have specific

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<v Speaker 1>locations and maybe these particles are actually tiny zero volume points.

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<v Speaker 1>And then quantum mechanics grew up and said, those waves

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<v Speaker 1>are actually even more important because the particles themselves are

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<v Speaker 1>just waves and quantum fields.

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<v Speaker 3>And so that's where.

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<v Speaker 1>We are now that we understand that all the matter

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<v Speaker 1>that's out there, the electron, the quarks inside the proton

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<v Speaker 1>and the neutron, all these things are actually just ripples

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<v Speaker 1>in quantum.

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<v Speaker 3>Fields, all right.

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<v Speaker 2>And there are a bunch of different kinds of fields.

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<v Speaker 2>We've talked about those before, right, And so are we

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<v Speaker 2>talking about a very particular kind of field that makes

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<v Speaker 2>up bananas and slots or are all the fields relevant?

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<v Speaker 1>So you're right, there are lots of different kinds of fields.

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<v Speaker 1>Every particle has a field. So the electron is a field,

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<v Speaker 1>the muon has a field, the cow has a field,

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<v Speaker 1>the top qrk has a field. Every different kind of

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<v Speaker 1>particle has a field. We don't understand why there are

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<v Speaker 1>so many. There're dozens of these fields. Every bit of

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<v Speaker 1>space that's out there has all these fields sitting on

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<v Speaker 1>top of each other in the same chunk of space.

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<v Speaker 1>It's kind of hard to wrap your mind around because

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<v Speaker 1>if you're thinking of like blankets, you know, blankets you

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<v Speaker 1>stack because they can't be in the same location. But

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<v Speaker 1>these fields are all in the same place, and they

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<v Speaker 1>can all oscillate independently. And you asked, which fields are

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<v Speaker 1>we talking about in this case, we're talking mostly about

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<v Speaker 1>the fields that make up us, which are electron fields,

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<v Speaker 1>and two of the cork fields, the upfield in the downfield.

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<v Speaker 1>So there are dozens of those fields out there, and

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<v Speaker 1>there's like big fundamental questions about what that means and

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<v Speaker 1>how do we unify them, and it can be simplified,

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<v Speaker 1>et cetera. But most of the matter in the universe

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<v Speaker 1>is made out of particles which are oscillations in three

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<v Speaker 1>of those fields, the electron field and then the up

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<v Speaker 1>and down cork fields which make the proton and the neutron.

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<v Speaker 1>And how do you understand like a particle being an

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<v Speaker 1>oscillation of a field, what does that really mean?

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<v Speaker 3>What are we talking about?

0:10:29.960 --> 0:10:31.960
<v Speaker 1>Well, when we say an oscillation of a field, we

0:10:32.040 --> 0:10:34.440
<v Speaker 1>really mean that it's vibrating, like the value of the

0:10:34.440 --> 0:10:37.560
<v Speaker 1>field is going up and down, and so because it's moving,

0:10:37.600 --> 0:10:40.680
<v Speaker 1>it can have kinetic energy. And as it has different values,

0:10:40.720 --> 0:10:42.880
<v Speaker 1>it can have potential energy. The way they like a

0:10:42.960 --> 0:10:45.400
<v Speaker 1>book on a shelf has a different potential energy if

0:10:45.400 --> 0:10:46.880
<v Speaker 1>it's on a high point of the shelf or a

0:10:46.920 --> 0:10:49.839
<v Speaker 1>low point on the shelf. Right, you like store energy

0:10:49.880 --> 0:10:51.800
<v Speaker 1>in a book by moving to the top of the shelf,

0:10:52.160 --> 0:10:54.240
<v Speaker 1>you release energy from the book when it falls off

0:10:54.280 --> 0:10:57.120
<v Speaker 1>the shelf. The same way these fields oscillate. They go

0:10:57.200 --> 0:10:59.200
<v Speaker 1>up and they go down, They slosh back and forth

0:10:59.320 --> 0:11:03.160
<v Speaker 1>between tential and kinetic energy, and so there's energy stored

0:11:03.200 --> 0:11:05.439
<v Speaker 1>in the field. So you should think of the particles

0:11:05.480 --> 0:11:08.319
<v Speaker 1>as like not a little dot of stuff, but instead

0:11:08.520 --> 0:11:11.320
<v Speaker 1>a little vibrating blob of energy in the field.

0:11:11.520 --> 0:11:13.400
<v Speaker 2>Oh way, already, like where this is going, I'm a

0:11:13.520 --> 0:11:16.560
<v Speaker 2>vibrating field of energy or made up of vibrating fields

0:11:16.559 --> 0:11:20.080
<v Speaker 2>of energy, and If so, why are the sloths so slow?

0:11:20.400 --> 0:11:22.840
<v Speaker 3>Exactly, they are filled with energy.

0:11:22.960 --> 0:11:24.000
<v Speaker 2>They should be all right.

0:11:24.040 --> 0:11:26.240
<v Speaker 1>So now we have these little vibrating fields of energy.

0:11:26.720 --> 0:11:28.520
<v Speaker 1>Grace's question is how do you put that together to

0:11:28.559 --> 0:11:29.679
<v Speaker 1>make a banana.

0:11:29.360 --> 0:11:29.920
<v Speaker 3>Or a sloth?

0:11:30.280 --> 0:11:32.960
<v Speaker 1>Basically, these things are super duper tiny, but they're not

0:11:33.080 --> 0:11:36.400
<v Speaker 1>like little volume cubes like legos. How do you put

0:11:36.400 --> 0:11:38.360
<v Speaker 1>them together to make something big?

0:11:38.800 --> 0:11:39.240
<v Speaker 3>Right?

0:11:39.240 --> 0:11:42.280
<v Speaker 1>Well, here's the crucial insight. You need the volume that

0:11:42.320 --> 0:11:46.360
<v Speaker 1>we experience. The reason things take up space is not

0:11:46.440 --> 0:11:49.520
<v Speaker 1>from the stuff that they make, but from their interactions

0:11:49.559 --> 0:11:52.000
<v Speaker 1>with each other. So it's not like you have two

0:11:52.000 --> 0:11:54.760
<v Speaker 1>particles and they have surfaces and those surfaces click together,

0:11:55.240 --> 0:11:57.320
<v Speaker 1>or even that they're like two tennis balls that you're

0:11:57.360 --> 0:12:01.600
<v Speaker 1>packing into a space and their surfaces are particles have

0:12:01.720 --> 0:12:04.640
<v Speaker 1>interactions with each other. They exchange energy. This energy we

0:12:04.640 --> 0:12:07.559
<v Speaker 1>were talking about slashing in the electron field or slashing

0:12:07.559 --> 0:12:10.480
<v Speaker 1>in the quarkfield. That energy can slide from one field

0:12:10.520 --> 0:12:13.240
<v Speaker 1>to another. That's when an interaction is so. For example,

0:12:13.280 --> 0:12:16.600
<v Speaker 1>an electron moving through space will also make ripples in

0:12:16.640 --> 0:12:21.360
<v Speaker 1>the electromagnetic field the photons field because those two fields interact.

0:12:21.400 --> 0:12:24.440
<v Speaker 1>There's a connection between those two fields and the ripples

0:12:24.440 --> 0:12:27.120
<v Speaker 1>in the electromagnetic field will then push or pull on

0:12:27.320 --> 0:12:30.839
<v Speaker 1>other electrons. So how do two electrons interact with each other?

0:12:30.920 --> 0:12:33.760
<v Speaker 1>Why do they repel? Because they are both making ripples

0:12:33.800 --> 0:12:36.840
<v Speaker 1>in the electromagnetic field, which has the capacity to affect

0:12:36.880 --> 0:12:37.800
<v Speaker 1>other electrons.

0:12:38.160 --> 0:12:39.920
<v Speaker 2>So I'm going to try to tie this back to biology.

0:12:39.960 --> 0:12:42.680
<v Speaker 2>So I'm thinking, you know, Christmas has ended and I'm

0:12:42.679 --> 0:12:46.120
<v Speaker 2>feeling like my body could do with fewer interactions. Is

0:12:46.160 --> 0:12:49.320
<v Speaker 2>there is there a way to think about it, like

0:12:49.360 --> 0:12:52.080
<v Speaker 2>as you go into calorie deficit, can you think about

0:12:52.120 --> 0:12:55.160
<v Speaker 2>it as like electrons sort of leaving the electric field?

0:12:55.320 --> 0:12:57.040
<v Speaker 2>Or am I just making this too complicated?

0:12:57.200 --> 0:12:58.959
<v Speaker 1>I think there's a Christmas analogy if we can do

0:12:59.000 --> 0:13:01.640
<v Speaker 1>use to understand here. Think about what happens at a

0:13:01.679 --> 0:13:04.199
<v Speaker 1>Christmas party. Right when you put people into a room

0:13:04.200 --> 0:13:07.360
<v Speaker 1>at a Christmas party, do they stack like sardines against

0:13:07.400 --> 0:13:09.880
<v Speaker 1>the wall or like physically phase on top of each

0:13:09.880 --> 0:13:12.360
<v Speaker 1>other and occupy the same space. No, they talk to

0:13:12.440 --> 0:13:15.320
<v Speaker 1>each other and they get like a comfortable distance from

0:13:15.400 --> 0:13:17.520
<v Speaker 1>each other. Right, So you're at a party, people are

0:13:17.520 --> 0:13:18.559
<v Speaker 1>sort of scattered.

0:13:18.200 --> 0:13:18.720
<v Speaker 3>Through a room.

0:13:19.160 --> 0:13:22.200
<v Speaker 1>You're all sipping your Christmas cocktails or whatever, and they're

0:13:22.240 --> 0:13:25.559
<v Speaker 1>not squeezed and touching each other. Right, there's this comfortable

0:13:25.600 --> 0:13:27.520
<v Speaker 1>distance because people are talking to each other and they

0:13:27.520 --> 0:13:30.160
<v Speaker 1>respect each other's personal space. The reason that we can

0:13:30.240 --> 0:13:32.880
<v Speaker 1>generate volume in a banana from a bunch of tiny

0:13:32.960 --> 0:13:35.400
<v Speaker 1>little particles, which are actually ripples in the fields, is

0:13:35.440 --> 0:13:37.640
<v Speaker 1>for the same reason that they have their own little

0:13:37.640 --> 0:13:41.640
<v Speaker 1>personal space. Their interactions keep them apart, and so like

0:13:41.840 --> 0:13:45.440
<v Speaker 1>inside your banana, are a bunch of little ripples that

0:13:45.520 --> 0:13:48.439
<v Speaker 1>are keeping their space between them because of their interactions.

0:13:48.480 --> 0:13:50.720
<v Speaker 1>So the volume of the material comes from the bonds

0:13:50.760 --> 0:13:54.160
<v Speaker 1>between these particles, these little ripples, not from like the

0:13:54.200 --> 0:13:56.840
<v Speaker 1>inherent volume of them, as they're stacked together on top

0:13:56.880 --> 0:13:59.000
<v Speaker 1>of each other. So let's zoom all the way in

0:13:59.080 --> 0:14:00.720
<v Speaker 1>and then out again, just to make sure it all

0:14:00.760 --> 0:14:03.560
<v Speaker 1>makes sense. We zoom as far in as we understand

0:14:03.600 --> 0:14:05.880
<v Speaker 1>the nature of the universe. We have these little ripples

0:14:05.880 --> 0:14:08.960
<v Speaker 1>and fields which are just little buzzing blobs of energy. Right,

0:14:09.000 --> 0:14:12.160
<v Speaker 1>particles are not little scoops of universe stuff. They are

0:14:12.200 --> 0:14:15.120
<v Speaker 1>little blobs of buzzing energy in the field, and the

0:14:15.160 --> 0:14:17.240
<v Speaker 1>fields interact with each other. So buzzing energy in the

0:14:17.280 --> 0:14:20.320
<v Speaker 1>electron field also means buzzing in the electromagnetic field, and

0:14:20.360 --> 0:14:22.600
<v Speaker 1>also in the Higgs field and all sorts of other fields.

0:14:22.680 --> 0:14:26.720
<v Speaker 1>Whatever the electron interacts with and interactions between those fields

0:14:26.840 --> 0:14:30.320
<v Speaker 1>keep these little buzzing blobs in harmony and in balance

0:14:30.520 --> 0:14:33.280
<v Speaker 1>and allow you to build up bigger things. So they're

0:14:33.320 --> 0:14:35.600
<v Speaker 1>not little lego bricks that you click together, but they

0:14:35.680 --> 0:14:38.200
<v Speaker 1>little buzzing blobs sort of in balance with each other,

0:14:38.320 --> 0:14:40.960
<v Speaker 1>keeping their space. And that's where the volume comes from.

0:14:41.160 --> 0:14:42.720
<v Speaker 1>So you zoom all the way out and you look

0:14:42.720 --> 0:14:44.960
<v Speaker 1>at a banana, should think of it as like a

0:14:45.160 --> 0:14:48.520
<v Speaker 1>matrix of these buzzing blobs that are all somehow in

0:14:48.600 --> 0:14:50.920
<v Speaker 1>balance with each other because of their interactions.

0:14:51.160 --> 0:14:53.360
<v Speaker 2>It doesn't sound beautiful, but you know, I study dumb

0:14:53.400 --> 0:14:56.920
<v Speaker 2>trucks full of dead fists, so who are to judge?

0:14:57.320 --> 0:14:59.240
<v Speaker 1>No, but I think that is like peeling back a

0:14:59.320 --> 0:15:02.040
<v Speaker 1>layer of reality, like seeing the matrix and like, oh,

0:15:02.040 --> 0:15:04.600
<v Speaker 1>this is what makes up the banana. And you know,

0:15:04.720 --> 0:15:08.000
<v Speaker 1>what's a banana in your mind is your experience the banana,

0:15:08.080 --> 0:15:11.200
<v Speaker 1>poking on it, pushing on and tasting it, whatever, chasing

0:15:11.200 --> 0:15:14.360
<v Speaker 1>that sloth, all these experiences of what build your sort

0:15:14.400 --> 0:15:16.800
<v Speaker 1>of your mental construct of the banana. But it's nice

0:15:16.840 --> 0:15:20.000
<v Speaker 1>to know, like mathematically, how that comes from the littlest

0:15:20.040 --> 0:15:22.120
<v Speaker 1>bits it's made out of. So thank you Grace for

0:15:22.160 --> 0:15:25.680
<v Speaker 1>asking that question. And we're curious if this answered your

0:15:25.760 --> 0:15:28.680
<v Speaker 1>question and if you have follow ups, So we'll ship

0:15:28.720 --> 0:15:30.360
<v Speaker 1>this off to Grace and we'll hear what she.

0:15:30.400 --> 0:15:31.000
<v Speaker 3>Has to say.

0:15:31.280 --> 0:15:33.600
<v Speaker 2>I also don't think answers have to be beautiful, but

0:15:33.600 --> 0:15:37.040
<v Speaker 2>maybe that's because I'm a biologist. Our answers are rarely.

0:15:36.760 --> 0:15:38.800
<v Speaker 3>Beautiful, but often they're insightful.

0:15:38.920 --> 0:15:41.080
<v Speaker 2>Yeah, I wasn't implying they weren't, Daniel. I don't know

0:15:41.080 --> 0:15:43.800
<v Speaker 2>why you felt you needed to say that, well.

0:15:45.440 --> 0:15:48.400
<v Speaker 1>Because that's where the beauty comes from, right the inside. Like, oh, no,

0:15:48.520 --> 0:15:51.160
<v Speaker 1>I understand this in a way I didn't before. Yeah,

0:15:51.200 --> 0:15:52.840
<v Speaker 1>it can still be gooey, it's true.

0:15:53.080 --> 0:15:56.360
<v Speaker 5>Hi, Daniel Keilly, thank you so much for answering our question.

0:15:56.720 --> 0:15:59.040
<v Speaker 5>I'm still not sure I understand all of it, but

0:15:59.120 --> 0:16:01.040
<v Speaker 5>it was really helpful here you explain it.

0:16:01.440 --> 0:16:04.080
<v Speaker 6>I agree, it's clear I need to change my mental

0:16:04.080 --> 0:16:07.280
<v Speaker 6>model of ways and particles stecking up like lego bricks

0:16:07.320 --> 0:16:10.720
<v Speaker 6>to make things like sloths and instead think about blobs

0:16:10.720 --> 0:16:13.440
<v Speaker 6>of energy. Thank you for all that you both do

0:16:13.680 --> 0:16:16.520
<v Speaker 6>to help educate us and break down complex topics and

0:16:16.600 --> 0:16:19.320
<v Speaker 6>have fun while doing it. I rate your answer a

0:16:19.400 --> 0:16:20.680
<v Speaker 6>solid A plus.

0:16:21.080 --> 0:16:22.000
<v Speaker 5>Thank you so much.

0:16:22.320 --> 0:16:43.480
<v Speaker 7>Bye.

0:16:44.120 --> 0:16:46.080
<v Speaker 2>All right, we're back and the next question is from

0:16:46.160 --> 0:16:49.120
<v Speaker 2>a listener who, when they emailed us, was working through

0:16:49.160 --> 0:16:52.440
<v Speaker 2>a very miserable cold. I believe they're feeling better now.

0:16:52.520 --> 0:16:53.800
<v Speaker 2>But here is their question.

0:16:54.280 --> 0:16:56.560
<v Speaker 8>A common COLDE seems to have a lot of variants,

0:16:56.920 --> 0:16:59.560
<v Speaker 8>But how quickly does it mutate? Such as for the

0:16:59.560 --> 0:17:02.680
<v Speaker 8>common I'm suffering with at the moment, Is there a

0:17:02.800 --> 0:17:06.720
<v Speaker 8>quantifiable percentage of my sneezing and coughing that I accidentally

0:17:06.960 --> 0:17:11.400
<v Speaker 8>spew onto others noticeably different compared to my original infection?

0:17:12.240 --> 0:17:16.640
<v Speaker 8>Or are the variants pretty rare? But given the billions

0:17:16.680 --> 0:17:19.480
<v Speaker 8>of us who get a cold that can create variants,

0:17:19.880 --> 0:17:23.359
<v Speaker 8>a big number times a small percentage can have a

0:17:23.400 --> 0:17:25.040
<v Speaker 8>surprisingly noticeable number.

0:17:25.440 --> 0:17:28.000
<v Speaker 1>Help me out, all right, this is a great question,

0:17:28.080 --> 0:17:30.640
<v Speaker 1>and it's sort of similar in spirit to the previous one, Right,

0:17:30.920 --> 0:17:35.040
<v Speaker 1>getting a microscopic understanding of a common experience, in this case,

0:17:35.080 --> 0:17:38.240
<v Speaker 1>the common cold. So let's see if biology can provide

0:17:38.280 --> 0:17:41.680
<v Speaker 1>the insights to give you that sense of understanding, even

0:17:41.720 --> 0:17:43.200
<v Speaker 1>if we are talking about mucus.

0:17:43.400 --> 0:17:46.439
<v Speaker 2>Well, let's give it a shot, all right, So it

0:17:46.480 --> 0:17:50.320
<v Speaker 2>gets complicated right from the beginning. The common cold. According

0:17:50.359 --> 0:17:53.160
<v Speaker 2>to the Centers for Disease Control, this is defined as

0:17:53.160 --> 0:17:56.359
<v Speaker 2>a viral infection of the upper respiratory track. Okay, okay,

0:17:56.600 --> 0:17:58.960
<v Speaker 2>but it turns out it's not caused by just one

0:17:59.040 --> 0:18:02.119
<v Speaker 2>kind of virus. It's caused by something like over two

0:18:02.240 --> 0:18:06.200
<v Speaker 2>hundred different kinds of viruses. But depending on the time

0:18:06.240 --> 0:18:09.080
<v Speaker 2>of year, between fifty to eighty percent of the common

0:18:09.080 --> 0:18:11.680
<v Speaker 2>colds that people have are caused by a group of

0:18:11.760 --> 0:18:15.560
<v Speaker 2>viruses called the rhinoviruses. So we're going to answer Tim's

0:18:15.640 --> 0:18:18.639
<v Speaker 2>question based on data that we've gotten in labs that

0:18:18.680 --> 0:18:20.160
<v Speaker 2>have looked at rhinoviruses.

0:18:20.440 --> 0:18:23.320
<v Speaker 1>So this is like asking, why is my house infected

0:18:23.359 --> 0:18:25.400
<v Speaker 1>with insects? Well, it turns out there's lots of different

0:18:25.480 --> 0:18:27.120
<v Speaker 1>kind of insects that couldn't infest your house.

0:18:27.320 --> 0:18:29.359
<v Speaker 2>That's right, that's right. And so to answer your question

0:18:29.760 --> 0:18:33.560
<v Speaker 2>without taking too many lifetimes, we need to narrow down

0:18:33.560 --> 0:18:37.199
<v Speaker 2>on an example. So we're narrowing down on the rhinoviruses.

0:18:37.440 --> 0:18:39.240
<v Speaker 1>And so for those of us who are not biologists,

0:18:39.280 --> 0:18:41.560
<v Speaker 1>remind us, like, what is a virus and how does

0:18:41.600 --> 0:18:42.000
<v Speaker 1>it work?

0:18:42.119 --> 0:18:42.920
<v Speaker 3>What is its plan?

0:18:43.560 --> 0:18:46.080
<v Speaker 2>Yeah, So what viruses do is when they get inside

0:18:46.080 --> 0:18:49.200
<v Speaker 2>of you, they have this way of injecting themselves into

0:18:49.240 --> 0:18:51.480
<v Speaker 2>your cell. So they've got like some machinery that helps

0:18:51.520 --> 0:18:53.560
<v Speaker 2>them move around, and then when they get to a cell,

0:18:53.600 --> 0:18:57.160
<v Speaker 2>they clamp down and then they inject genetic material into

0:18:57.160 --> 0:18:57.520
<v Speaker 2>the cell.

0:18:58.000 --> 0:19:01.840
<v Speaker 1>This is amazing. It's empazing. It sounds so mechanical.

0:19:02.040 --> 0:19:04.439
<v Speaker 2>It does. Yeah, I know, sometimes biology is just as

0:19:04.440 --> 0:19:10.159
<v Speaker 2>good as Sci Fi, maybe better. So they hijack the

0:19:10.200 --> 0:19:13.800
<v Speaker 2>cell's machinery and they get the cell to start replicating

0:19:13.840 --> 0:19:16.720
<v Speaker 2>the virus. And this is part of where Tim's question

0:19:16.800 --> 0:19:20.720
<v Speaker 2>comes in. As the virus replicates, sometimes mistakes are made,

0:19:21.080 --> 0:19:24.440
<v Speaker 2>and cold viruses tend to not correct these genetic mistakes

0:19:24.720 --> 0:19:26.520
<v Speaker 2>very often, and so we're going to get to that

0:19:26.520 --> 0:19:28.359
<v Speaker 2>in a little bit more detail layered. So the host

0:19:28.400 --> 0:19:32.000
<v Speaker 2>cell replicates the virus many times, and then the virus

0:19:32.080 --> 0:19:34.520
<v Speaker 2>breaks out of the cell and goes and completes that

0:19:34.560 --> 0:19:35.359
<v Speaker 2>cycle again.

0:19:35.440 --> 0:19:37.280
<v Speaker 1>So the element of the cell that is taking over

0:19:37.480 --> 0:19:39.919
<v Speaker 1>is the bit where it replicates the genetic material. That's

0:19:39.960 --> 0:19:42.080
<v Speaker 1>what the virus can't do for itself. Yes, so this

0:19:42.200 --> 0:19:45.239
<v Speaker 1>is like a hacker breaking into a publishing house. And

0:19:45.280 --> 0:19:48.400
<v Speaker 1>getting it to print his personal manifesto instead of whatever

0:19:48.440 --> 0:19:49.560
<v Speaker 1>it was going to print otherwise.

0:19:49.640 --> 0:19:51.879
<v Speaker 2>That's right, yep. Print it's pamphlets over and over and

0:19:51.920 --> 0:19:55.320
<v Speaker 2>over again. And then through some mechanism that sort of

0:19:55.320 --> 0:19:58.439
<v Speaker 2>breaks the metaphor, it sneaks into another publishing house and

0:19:58.440 --> 0:20:00.000
<v Speaker 2>does the same thing over and over and over again

0:20:01.000 --> 0:20:06.320
<v Speaker 2>until you stop sneezing. So anyway, so it goes through

0:20:06.359 --> 0:20:09.879
<v Speaker 2>this process, and it is finding cells in particular in

0:20:09.920 --> 0:20:13.119
<v Speaker 2>like your nasal passage and your lungs, and it's replicating

0:20:13.119 --> 0:20:16.280
<v Speaker 2>in there. And as it replicates, your immune system sort

0:20:16.320 --> 0:20:19.520
<v Speaker 2>of amps up and starts attacking it. And this cold

0:20:19.600 --> 0:20:21.720
<v Speaker 2>process can last for about a week, and so you

0:20:21.800 --> 0:20:24.600
<v Speaker 2>get a build up of virus particles and then your

0:20:24.600 --> 0:20:27.280
<v Speaker 2>immune system starts to get it in control, and the

0:20:27.280 --> 0:20:29.280
<v Speaker 2>density of virus goes down over time.

0:20:29.680 --> 0:20:31.800
<v Speaker 1>And so if I've had the common cold and my

0:20:31.800 --> 0:20:34.280
<v Speaker 1>immune system has figured out how to combat it, why

0:20:34.280 --> 0:20:36.400
<v Speaker 1>do I then get the common cold again the next

0:20:36.480 --> 0:20:38.520
<v Speaker 1>year or three weeks later when my kids come back

0:20:38.520 --> 0:20:39.280
<v Speaker 1>with a different one.

0:20:39.359 --> 0:20:42.800
<v Speaker 2>Well, that great question brings me to mutation rates. So,

0:20:43.240 --> 0:20:46.840
<v Speaker 2>as I mentioned, the virus doesn't correct mistakes as often

0:20:47.000 --> 0:20:50.600
<v Speaker 2>as for example, human cells do. And so the question

0:20:50.680 --> 0:20:52.960
<v Speaker 2>that we want to ask here to really address Tim's

0:20:53.080 --> 0:20:55.840
<v Speaker 2>question is how many mutations do you tend to get

0:20:55.880 --> 0:20:58.080
<v Speaker 2>and how much do they build up? So I found

0:20:58.240 --> 0:21:02.199
<v Speaker 2>estimates that the mutation rate is you get something like

0:21:02.520 --> 0:21:05.240
<v Speaker 2>ten to the negative three to ten to the negative

0:21:05.280 --> 0:21:08.360
<v Speaker 2>five mutations, and ten to the negative three is one

0:21:08.400 --> 0:21:11.600
<v Speaker 2>in a thousand, one in a thousand. Yeah, per nucleotide,

0:21:11.640 --> 0:21:15.160
<v Speaker 2>per genome replication event. Don't worry about all of those numbers.

0:21:15.160 --> 0:21:18.960
<v Speaker 2>The point is that a virus is about seven two

0:21:19.040 --> 0:21:22.200
<v Speaker 2>hundred pieces long, and each time it replicates, you usually

0:21:22.280 --> 0:21:25.879
<v Speaker 2>end up with about one mutation on average in that

0:21:25.960 --> 0:21:26.760
<v Speaker 2>genetic code.

0:21:26.920 --> 0:21:28.920
<v Speaker 1>So it's getting the cell to replicate it, but it's

0:21:28.920 --> 0:21:30.280
<v Speaker 1>not a perfect copy.

0:21:30.040 --> 0:21:31.960
<v Speaker 2>That's right, and then it doesn't get corrected, and so

0:21:32.080 --> 0:21:35.199
<v Speaker 2>that error goes on to the next cell and that

0:21:35.320 --> 0:21:37.080
<v Speaker 2>gets replicated over and over again.

0:21:37.240 --> 0:21:40.720
<v Speaker 1>So already the initial virus that infected Tim, all of

0:21:40.760 --> 0:21:43.960
<v Speaker 1>its little babies likely are different than it was by

0:21:44.080 --> 0:21:46.360
<v Speaker 1>one nucleotide.

0:21:45.560 --> 0:21:47.320
<v Speaker 2>That's right. And so then the question you want to

0:21:47.320 --> 0:21:49.800
<v Speaker 2>ask yourself is does that matter? And I think a

0:21:49.800 --> 0:21:51.520
<v Speaker 2>lot of the time it's not going to matter. So

0:21:51.600 --> 0:21:54.639
<v Speaker 2>a lot of mutations don't change the kind of protein

0:21:54.680 --> 0:21:56.760
<v Speaker 2>that ends up getting made, or they don't have any

0:21:56.800 --> 0:22:00.960
<v Speaker 2>meaningful change based on this one little that flips to

0:22:01.000 --> 0:22:01.720
<v Speaker 2>a different value.

0:22:01.880 --> 0:22:02.000
<v Speaker 3>Right.

0:22:02.000 --> 0:22:04.440
<v Speaker 1>It's not like the common cold suddenly becomes a completely

0:22:04.480 --> 0:22:07.119
<v Speaker 1>different disease measles all of a sudden with one slip

0:22:07.200 --> 0:22:07.639
<v Speaker 1>or something.

0:22:07.840 --> 0:22:10.280
<v Speaker 2>Right. But you know, as Tim noted in his question,

0:22:10.400 --> 0:22:12.879
<v Speaker 2>if this is happening many many times in your body,

0:22:13.240 --> 0:22:15.520
<v Speaker 2>and then it's happening to many many people, these changes

0:22:15.520 --> 0:22:18.560
<v Speaker 2>can add up over time. Amazingly. This all seems to

0:22:18.600 --> 0:22:21.199
<v Speaker 2>also be temperature dependent. And I have a lot of

0:22:21.240 --> 0:22:23.680
<v Speaker 2>friends who will say things like, oh, don't go outside

0:22:23.720 --> 0:22:26.200
<v Speaker 2>without a coat on. It's cold out, and then you're

0:22:26.200 --> 0:22:28.720
<v Speaker 2>gonna get sick. And that's not quite how it works.

0:22:28.760 --> 0:22:33.280
<v Speaker 2>But there is some evidence that at colder temperatures, cold

0:22:33.400 --> 0:22:36.880
<v Speaker 2>viruses do replicate more quickly in mice. I don't think

0:22:36.880 --> 0:22:38.760
<v Speaker 2>this has been done in humans. It's always in mice.

0:22:39.240 --> 0:22:41.720
<v Speaker 2>But it's not because that's better for the virus in

0:22:41.760 --> 0:22:44.199
<v Speaker 2>some way, which I think is implied when they're like, oh,

0:22:44.200 --> 0:22:46.520
<v Speaker 2>don't go outside without your coat on. It's because the

0:22:46.560 --> 0:22:50.320
<v Speaker 2>immune systems in mice seem to react less strongly at

0:22:50.359 --> 0:22:54.200
<v Speaker 2>low temperatures. So these replication rates that we're talking about here,

0:22:54.240 --> 0:22:56.359
<v Speaker 2>they're all a little bit handwavy, and they depend on

0:22:56.400 --> 0:22:58.640
<v Speaker 2>what temperature you're at, and so Tim, I hope you're

0:22:58.640 --> 0:23:01.320
<v Speaker 2>staying nice and warm. Yeah, So what do we know

0:23:01.520 --> 0:23:04.760
<v Speaker 2>about how much the cell replicates inside of a host?

0:23:05.160 --> 0:23:09.159
<v Speaker 2>And the answer is well as complicated. So at a

0:23:09.200 --> 0:23:11.600
<v Speaker 2>lot of our data come from what I think of

0:23:11.640 --> 0:23:14.439
<v Speaker 2>as the wrong kinds of cells in the lab. And

0:23:14.480 --> 0:23:16.840
<v Speaker 2>so the cells that are often used in these experiments

0:23:16.840 --> 0:23:19.600
<v Speaker 2>are HeLa cells. So these are I think ovarian cells

0:23:19.640 --> 0:23:23.000
<v Speaker 2>collected from a woman named Henriette Lex a long time ago.

0:23:23.000 --> 0:23:24.560
<v Speaker 2>They were collected without her permission.

0:23:24.960 --> 0:23:26.360
<v Speaker 1>Bad bad biologists.

0:23:26.440 --> 0:23:26.760
<v Speaker 3>Bad.

0:23:27.119 --> 0:23:31.240
<v Speaker 2>Yeah, yeah, no, bad biologists. You're right, I'll take that one.

0:23:31.560 --> 0:23:33.080
<v Speaker 1>I mean, we've never gotten consent from any of the

0:23:33.080 --> 0:23:35.040
<v Speaker 1>protons we've destroyed, but I don't think they are the

0:23:35.040 --> 0:23:35.520
<v Speaker 1>same rights.

0:23:35.600 --> 0:23:38.680
<v Speaker 2>Yeah, no, it's you're right. This was not a bright

0:23:38.760 --> 0:23:42.200
<v Speaker 2>spot in the history of biology. So we stole those cells.

0:23:42.240 --> 0:23:44.159
<v Speaker 2>There's a whole very interesting book on that which I

0:23:44.200 --> 0:23:47.040
<v Speaker 2>recommend people check out. But anyway, so these cells are

0:23:47.040 --> 0:23:49.320
<v Speaker 2>really great at surviving in the lab, and so we

0:23:49.400 --> 0:23:52.360
<v Speaker 2>will infect them with cold viruses and see how they replicate.

0:23:52.440 --> 0:23:54.800
<v Speaker 2>But the problem is they're ovarian cells. They're not like

0:23:54.880 --> 0:23:58.280
<v Speaker 2>nasal passage cells, and the body is complicated. So just

0:23:58.280 --> 0:24:00.040
<v Speaker 2>because something happens in a petri dish, does it I

0:24:00.040 --> 0:24:02.359
<v Speaker 2>mean it would happen the same in a body. So

0:24:02.560 --> 0:24:06.360
<v Speaker 2>when a cell explodes, how many baby viruses are made?

0:24:06.560 --> 0:24:09.679
<v Speaker 2>And the answer is probably something like one hundred thousand,

0:24:09.760 --> 0:24:12.760
<v Speaker 2>maybe even more than that. And then how long is

0:24:12.800 --> 0:24:16.480
<v Speaker 2>the cycle of infection before you get an explosion? And

0:24:16.840 --> 0:24:20.320
<v Speaker 2>you know, we don't really know. It's probably longer than minutes,

0:24:20.400 --> 0:24:22.800
<v Speaker 2>but less than weeks, which is a pretty big timeframe.

0:24:22.880 --> 0:24:25.760
<v Speaker 2>And thank you so much to Katrina Whitson for giving

0:24:25.840 --> 0:24:28.520
<v Speaker 2>us this information, because I was having trouble sort of

0:24:28.640 --> 0:24:31.480
<v Speaker 2>narrowing down the numbers to use for this question, and I.

0:24:31.400 --> 0:24:33.760
<v Speaker 1>Think Coatinia would probably want me to emphasize that these

0:24:33.920 --> 0:24:36.919
<v Speaker 1>are very fuzzy numbers because it's a research question. Nobody

0:24:36.960 --> 0:24:38.840
<v Speaker 1>knows the answer to these things, which is sort of

0:24:39.080 --> 0:24:42.040
<v Speaker 1>shocking and amazing, but it's hard to measure. And she

0:24:42.119 --> 0:24:44.760
<v Speaker 1>was also telling me that sometimes a virus wants to

0:24:44.800 --> 0:24:47.200
<v Speaker 1>slow down how long the process takes because it wants

0:24:47.200 --> 0:24:50.119
<v Speaker 1>the cell to get like stronger and fatter before it explodes.

0:24:50.480 --> 0:24:52.359
<v Speaker 1>So sometimes they like beef up the cell, sort of

0:24:52.400 --> 0:24:54.159
<v Speaker 1>like fattening a calf before you kill it.

0:24:54.200 --> 0:24:56.000
<v Speaker 2>That's right, And so as a group effort, I would

0:24:56.040 --> 0:25:00.119
<v Speaker 2>say the Whitesn Research Institute plus adjunct faculty member or

0:25:00.160 --> 0:25:04.880
<v Speaker 2>Kelly Wiener Smith decided that the virus that you sneeze

0:25:04.880 --> 0:25:07.320
<v Speaker 2>out sort of towards the end of your cold probably

0:25:07.359 --> 0:25:10.240
<v Speaker 2>has something like twenty mutations and is about one percent

0:25:10.320 --> 0:25:13.520
<v Speaker 2>different than the virus that you were infected by GO team.

0:25:15.440 --> 0:25:18.119
<v Speaker 2>But Tim wanted to know if it was noticeably variable,

0:25:18.200 --> 0:25:20.760
<v Speaker 2>and we've mentioned that it really depends where those mutations

0:25:20.760 --> 0:25:23.960
<v Speaker 2>are happening. But over time this is adding up. The

0:25:24.000 --> 0:25:27.800
<v Speaker 2>cold virus does end up being noticeably variable enough that

0:25:27.840 --> 0:25:30.560
<v Speaker 2>it's really hard to make a vaccine for the cold.

0:25:31.000 --> 0:25:33.080
<v Speaker 2>And this is for a couple reasons. So one, we've

0:25:33.119 --> 0:25:35.720
<v Speaker 2>already mentioned that there's like something like two hundred different

0:25:35.800 --> 0:25:39.359
<v Speaker 2>kinds of viruses that can cause colds. Additionally, each strain

0:25:39.400 --> 0:25:42.480
<v Speaker 2>of the cold virus is replicating pretty rapidly, so from

0:25:42.520 --> 0:25:44.399
<v Speaker 2>one season to another it might be different enough that

0:25:44.440 --> 0:25:47.760
<v Speaker 2>the vaccine wouldn't work. And additionally, colds don't tend to

0:25:47.760 --> 0:25:50.800
<v Speaker 2>be as serious as something like the flu, So there's

0:25:50.840 --> 0:25:53.400
<v Speaker 2>not a lot of impetus to try to create a vaccine,

0:25:53.440 --> 0:25:56.520
<v Speaker 2>even though I sure would love to have not spent

0:25:56.920 --> 0:25:59.320
<v Speaker 2>oh my gosh, when my kids started elementary school, I

0:25:59.320 --> 0:26:01.399
<v Speaker 2>think I spent like sixty percent of my time at

0:26:01.400 --> 0:26:03.480
<v Speaker 2>home with a cold. I would have loved to have

0:26:03.560 --> 0:26:06.520
<v Speaker 2>had that time back. But what are you gonna do?

0:26:06.840 --> 0:26:10.440
<v Speaker 1>And that's interesting because colds are varying constantly and it's

0:26:10.560 --> 0:26:13.560
<v Speaker 1>hard to maintain immunity against them. Yet they mostly feel

0:26:13.560 --> 0:26:15.720
<v Speaker 1>the same, right, Yeah, yeah, you got a head cold

0:26:15.760 --> 0:26:17.600
<v Speaker 1>or a chest cold or whatever. But it's not like,

0:26:17.880 --> 0:26:20.600
<v Speaker 1>oh wow, this one makes my head green, or now

0:26:20.640 --> 0:26:23.440
<v Speaker 1>my thumb is swollen or something. It's basically the same disease,

0:26:23.480 --> 0:26:24.280
<v Speaker 1>it feels like to me.

0:26:24.480 --> 0:26:26.240
<v Speaker 2>Yeah, no, it feels that way to me as well.

0:26:26.520 --> 0:26:28.879
<v Speaker 2>And just to be clear, the flu viruses are also

0:26:28.960 --> 0:26:30.959
<v Speaker 2>doing quite a bit of mutating, but I think they

0:26:31.040 --> 0:26:33.240
<v Speaker 2>mutate a little bit less. But every year, the reason

0:26:33.240 --> 0:26:35.960
<v Speaker 2>you get a new flu vaccine is because that vaccine

0:26:36.040 --> 0:26:38.080
<v Speaker 2>is meant to replicate the strains of the flu that

0:26:38.119 --> 0:26:39.919
<v Speaker 2>we think are going to be most common in a

0:26:39.920 --> 0:26:42.880
<v Speaker 2>given year, Given like mutations that we've seen in those

0:26:42.920 --> 0:26:44.879
<v Speaker 2>flu virus strains in the past.

0:26:45.280 --> 0:26:47.040
<v Speaker 1>Yeah, And I think there's a lot of detective work

0:26:47.040 --> 0:26:49.320
<v Speaker 1>and guesswork that goes into the flu. Right, they're like

0:26:49.359 --> 0:26:51.880
<v Speaker 1>thinking about what it might be because they obviously don't

0:26:51.880 --> 0:26:54.480
<v Speaker 1>have the examples for the flu that's gonna come.

0:26:54.320 --> 0:26:54.840
<v Speaker 3>In the future.

0:26:54.960 --> 0:26:57.679
<v Speaker 2>Yep, exactly. I mean they're making their guests based on

0:26:57.800 --> 0:26:59.800
<v Speaker 2>years of data, looking at trends and how this stuff

0:26:59.800 --> 0:27:01.560
<v Speaker 2>plays out. But you're right, at the end of the day,

0:27:01.600 --> 0:27:03.760
<v Speaker 2>you just need to guess which flu strains are going

0:27:03.800 --> 0:27:06.000
<v Speaker 2>to be the most important ones to make vaccines against.

0:27:06.400 --> 0:27:07.320
<v Speaker 2>And I hope you got it.

0:27:07.359 --> 0:27:10.520
<v Speaker 1>Right thanks to folks working on the front lines of

0:27:10.520 --> 0:27:11.120
<v Speaker 1>public health.

0:27:11.200 --> 0:27:13.720
<v Speaker 2>Yes, oh my gosh, they're the best. All right, Tim,

0:27:13.800 --> 0:27:16.000
<v Speaker 2>We hope you're feeling better, and let's find out if

0:27:16.080 --> 0:27:17.600
<v Speaker 2>we were able to answer your question.

0:27:18.080 --> 0:27:21.560
<v Speaker 9>Yes, that answer my question. And wow, that is rather

0:27:21.640 --> 0:27:24.639
<v Speaker 9>terrifying that two hundred variants out there make up the

0:27:24.960 --> 0:27:27.840
<v Speaker 9>cold virus. I don't know if I'm going to sleep

0:27:27.840 --> 0:27:29.800
<v Speaker 9>well at night knowing that fact on top of all

0:27:29.880 --> 0:27:33.440
<v Speaker 9>the other mutation rates. But luckily we feel a little

0:27:33.440 --> 0:27:51.480
<v Speaker 9>bit on the safe side.

0:27:54.800 --> 0:27:55.200
<v Speaker 3>All right.

0:27:55.240 --> 0:27:58.200
<v Speaker 1>And our last question comes from Mark in Newcastle, who

0:27:58.240 --> 0:28:02.280
<v Speaker 1>asks a very heavy question about something very ephemeral.

0:28:02.680 --> 0:28:06.120
<v Speaker 10>Hi guys, it's Markia from Newcastle upon Tyne in the UK,

0:28:06.320 --> 0:28:08.959
<v Speaker 10>and I've got a question for you about data. I

0:28:09.000 --> 0:28:11.919
<v Speaker 10>was recently working on a project with my orduino writing

0:28:11.960 --> 0:28:15.040
<v Speaker 10>to some SD cards and of course when you switch

0:28:15.119 --> 0:28:16.880
<v Speaker 10>off the power and switch it back on, the data

0:28:16.920 --> 0:28:20.880
<v Speaker 10>is retained. So these cards do store something. This storing

0:28:21.000 --> 0:28:26.000
<v Speaker 10>charge and charge is electrons. Electrons have mass, So does

0:28:26.119 --> 0:28:30.200
<v Speaker 10>data have mass? Would an SD card full of data

0:28:30.400 --> 0:28:33.920
<v Speaker 10>way more than an SD card that didn't I guess

0:28:33.920 --> 0:28:36.320
<v Speaker 10>this is an extra opulation of this question, how much

0:28:36.359 --> 0:28:39.000
<v Speaker 10>does the Internet Way? Book pops for another day.

0:28:39.440 --> 0:28:41.480
<v Speaker 2>This is such a great question because, well, for a

0:28:41.520 --> 0:28:44.000
<v Speaker 2>variety of reasons. But I love this question because in

0:28:44.040 --> 0:28:46.280
<v Speaker 2>the past on this show you have said that when

0:28:46.320 --> 0:28:49.920
<v Speaker 2>a Tesla battery is charged, it weighs more than when

0:28:50.000 --> 0:28:53.960
<v Speaker 2>it's not charged, And that makes sense now, but at

0:28:54.000 --> 0:28:56.440
<v Speaker 2>the moment it totally surprised me and I didn't expect that.

0:28:56.600 --> 0:28:59.240
<v Speaker 2>And so, yeah, how much does the Internet Way.

0:28:59.160 --> 0:29:02.760
<v Speaker 3>Daniel seven at weighs seven?

0:29:02.880 --> 0:29:04.840
<v Speaker 2>Oh good, I was going to guess forty two.

0:29:04.960 --> 0:29:08.320
<v Speaker 1>Yeah, remember that mass as a measure of internal stored energy,

0:29:08.680 --> 0:29:11.400
<v Speaker 1>So if you increase the internal stored energy of an object,

0:29:11.800 --> 0:29:13.480
<v Speaker 1>then you are increasing its mass.

0:29:13.880 --> 0:29:14.720
<v Speaker 3>Like if you have a.

0:29:14.720 --> 0:29:16.480
<v Speaker 1>Rock and use zapp it with a photon and it

0:29:16.520 --> 0:29:19.800
<v Speaker 1>gets hotter, it also has more mass. Now, so when

0:29:19.800 --> 0:29:22.680
<v Speaker 1>you charge your Tesla battery, you're giving it more energy,

0:29:23.040 --> 0:29:25.920
<v Speaker 1>not because you're adding more electrons, you know, like physically

0:29:25.920 --> 0:29:29.000
<v Speaker 1>adding more scoops of universe stuff. Just giving more energy

0:29:29.040 --> 0:29:31.880
<v Speaker 1>to that configuration does increase the mass of the battery.

0:29:32.120 --> 0:29:35.160
<v Speaker 1>Since equals mc squared and C squared is a really

0:29:35.160 --> 0:29:37.880
<v Speaker 1>big number, you need an enormous amount of energy to

0:29:37.920 --> 0:29:41.120
<v Speaker 1>make a tiny increase in mass. So nobody really notices this,

0:29:41.440 --> 0:29:44.320
<v Speaker 1>and that's why. But Mark's question is sort of related.

0:29:44.560 --> 0:29:48.440
<v Speaker 1>He's asking about whether the arrangements to configuration of information

0:29:49.040 --> 0:29:52.520
<v Speaker 1>on his SD card or on your hard drive or

0:29:52.520 --> 0:29:55.800
<v Speaker 1>in your brain also has mass, which is a really

0:29:55.840 --> 0:30:00.400
<v Speaker 1>fascinating question and touches on deep concepts about information and entropy.

0:30:00.600 --> 0:30:04.080
<v Speaker 2>And we luckily have someone who is part computer scientist,

0:30:04.120 --> 0:30:07.920
<v Speaker 2>part physicists who is absolutely prepared to answer this question

0:30:08.000 --> 0:30:08.360
<v Speaker 2>for us.

0:30:09.600 --> 0:30:12.320
<v Speaker 1>Yeah, so information is really fascinating. It's hard to think

0:30:12.360 --> 0:30:16.560
<v Speaker 1>about like whether information has mass because information seems sort

0:30:16.600 --> 0:30:20.080
<v Speaker 1>of subjective, right, like, if you have a hard drive

0:30:20.360 --> 0:30:23.400
<v Speaker 1>and it has just random ones and zeros on it,

0:30:23.440 --> 0:30:25.800
<v Speaker 1>does it have more or less information than if you

0:30:25.840 --> 0:30:28.560
<v Speaker 1>put a picture of your dog on the hard drive? Well,

0:30:28.600 --> 0:30:31.080
<v Speaker 1>it depends, like do you consider the picture of your

0:30:31.080 --> 0:30:33.720
<v Speaker 1>dog to be useful or information in some way?

0:30:33.840 --> 0:30:34.040
<v Speaker 3>Right?

0:30:34.680 --> 0:30:37.000
<v Speaker 1>Or like did you encrypt the picture of your dog?

0:30:37.360 --> 0:30:41.200
<v Speaker 1>Because the best encryption algorithms make data that's valuable it

0:30:41.200 --> 0:30:44.320
<v Speaker 1>has some information look like random noise. So you can

0:30:44.360 --> 0:30:46.280
<v Speaker 1>imagine a scenario where you, like, you take a picture

0:30:46.280 --> 0:30:47.680
<v Speaker 1>of your dog, you put it on the hard drive,

0:30:47.920 --> 0:30:50.640
<v Speaker 1>looks like your dog, then you encrypt it. Somebody else

0:30:50.680 --> 0:30:53.000
<v Speaker 1>coming along is like, no, that's just random noise. There's

0:30:53.000 --> 0:30:56.000
<v Speaker 1>no information. And what if you, like, lose the password,

0:30:56.120 --> 0:30:59.640
<v Speaker 1>has the information decreased? And so information turns out to

0:30:59.640 --> 0:31:03.120
<v Speaker 1>be a fascinatingly subjective concept, which makes it very hard

0:31:03.160 --> 0:31:05.600
<v Speaker 1>to link to masks because mass is something physical and

0:31:05.680 --> 0:31:08.480
<v Speaker 1>invariant that everybody agrees on that you can like measure

0:31:08.560 --> 0:31:10.840
<v Speaker 1>without knowing about dogs or passwords?

0:31:10.960 --> 0:31:14.080
<v Speaker 2>Should I be thinking about information differently than I think

0:31:14.120 --> 0:31:17.200
<v Speaker 2>about like you know, before I put my PowerPoint presentation

0:31:17.280 --> 0:31:21.280
<v Speaker 2>on my SD card, it has fifty megabytes of data

0:31:21.360 --> 0:31:23.760
<v Speaker 2>and after the PowerPoint presentation is on there, it has

0:31:23.760 --> 0:31:29.280
<v Speaker 2>one thy fifty. So how is information different than megabytes?

0:31:29.760 --> 0:31:31.360
<v Speaker 1>Yeah, if you have an empty disc and then you

0:31:31.400 --> 0:31:34.560
<v Speaker 1>put files on there, it's counting, like how much of

0:31:34.560 --> 0:31:38.080
<v Speaker 1>the drive has information you've put on there. There could

0:31:38.160 --> 0:31:40.840
<v Speaker 1>also be information on the other bits that it's not counting,

0:31:41.200 --> 0:31:42.840
<v Speaker 1>maybe somebody else put it on there, but then you

0:31:43.000 --> 0:31:45.320
<v Speaker 1>format it the drive, so you consider it to be empty.

0:31:45.520 --> 0:31:47.880
<v Speaker 1>So it's a different question of like when you're filling

0:31:48.000 --> 0:31:50.400
<v Speaker 1>up the drive, right, because it's just like using some

0:31:50.480 --> 0:31:53.560
<v Speaker 1>of the bits for this rather than considering them unused.

0:31:53.880 --> 0:31:56.560
<v Speaker 1>But the question of information is subtle, and we're going

0:31:56.600 --> 0:31:58.880
<v Speaker 1>to have to dip into our understanding of entropy in

0:31:58.960 --> 0:32:00.880
<v Speaker 1>order to understand it, because it's turns out these two

0:32:00.920 --> 0:32:02.320
<v Speaker 1>concepts are closely related.

0:32:02.720 --> 0:32:05.800
<v Speaker 2>So okay, So just to clarify, then, information is not

0:32:06.440 --> 0:32:11.000
<v Speaker 2>how much stuff is on a card, it's how informative

0:32:11.360 --> 0:32:12.560
<v Speaker 2>is the thing?

0:32:12.920 --> 0:32:14.480
<v Speaker 1>Yeah, Because you could take a card and just fill

0:32:14.520 --> 0:32:17.320
<v Speaker 1>it with random ones and zeros, right, there's no information

0:32:17.400 --> 0:32:19.280
<v Speaker 1>there for you. So just because you put a big

0:32:19.280 --> 0:32:21.160
<v Speaker 1>file in your hard drive doesn't mean you add a

0:32:21.160 --> 0:32:23.360
<v Speaker 1>lot of information. It's about the contents and this seems

0:32:23.400 --> 0:32:27.400
<v Speaker 1>really subjective, and physics is all about equations and crisp definitions.

0:32:27.760 --> 0:32:30.400
<v Speaker 1>So how do we think about information from the point

0:32:30.400 --> 0:32:33.440
<v Speaker 1>of view of science and physics. So Claude Shannon defined

0:32:33.480 --> 0:32:35.200
<v Speaker 1>this in the middle of the last century. He was

0:32:35.200 --> 0:32:37.480
<v Speaker 1>thinking about this and he came up with something of

0:32:37.520 --> 0:32:40.800
<v Speaker 1>an arbitrary but very useful definition of information, and he

0:32:40.840 --> 0:32:43.680
<v Speaker 1>defines it as how much you have learned, how much

0:32:43.760 --> 0:32:47.520
<v Speaker 1>surprising information you have gained. So he was imagining like,

0:32:47.680 --> 0:32:50.120
<v Speaker 1>I'm communicating to you by sending you symbols across some

0:32:50.240 --> 0:32:53.000
<v Speaker 1>channel ones and zero's on a hard drive or you know,

0:32:53.160 --> 0:32:56.240
<v Speaker 1>text on a phone or whatever, and you want to

0:32:56.240 --> 0:32:59.080
<v Speaker 1>measure how much information is in these messages from Daniel

0:32:59.440 --> 0:33:02.960
<v Speaker 1>and to his definition, if when you learn something surprising,

0:33:03.360 --> 0:33:06.120
<v Speaker 1>that's high information. If you learn something you already know,

0:33:06.320 --> 0:33:09.640
<v Speaker 1>that's low information. So for example, let's say every day

0:33:09.680 --> 0:33:11.760
<v Speaker 1>I text you and I say, hey, Kelly, the earth

0:33:11.760 --> 0:33:14.240
<v Speaker 1>didn't explode last nightew every day you look at it

0:33:14.240 --> 0:33:17.760
<v Speaker 1>and you're like, Okay, that's not a surprise, right, this

0:33:17.800 --> 0:33:19.480
<v Speaker 1>has happened every day so far in my life.

0:33:19.560 --> 0:33:22.000
<v Speaker 2>I'm changing my phone number. Leave me alone, Daniel.

0:33:23.800 --> 0:33:26.200
<v Speaker 1>Why a physicists text me about the planet's exploding.

0:33:26.800 --> 0:33:27.520
<v Speaker 3>What did I do wrong?

0:33:27.640 --> 0:33:28.320
<v Speaker 2>Low information?

0:33:28.560 --> 0:33:32.400
<v Speaker 1>Low information exactly because it's something you expected to happen.

0:33:32.680 --> 0:33:34.800
<v Speaker 1>So the fact that it happened you didn't really learn much.

0:33:35.040 --> 0:33:36.520
<v Speaker 1>If one day I texted you I was like, by

0:33:36.600 --> 0:33:39.320
<v Speaker 1>the way, at two am, the Earth exploded, you'd be like, wow,

0:33:39.360 --> 0:33:41.800
<v Speaker 1>that's news to me, right, this is big information.

0:33:41.920 --> 0:33:44.120
<v Speaker 2>But wouldn't that also be low information because I would

0:33:44.200 --> 0:33:46.280
<v Speaker 2>have been exploded and I would have also been like,

0:33:46.520 --> 0:33:48.320
<v Speaker 2>thanks for being late to the party, Daniel.

0:33:48.480 --> 0:33:52.200
<v Speaker 1>Don't use the practical details of my analogy to confuse you, audience.

0:33:53.320 --> 0:33:56.000
<v Speaker 2>Okay, whoa, Oh no, I didn't know that, Daniel.

0:33:56.440 --> 0:33:58.720
<v Speaker 1>You're living in a city on Mars in this example.

0:33:58.880 --> 0:34:01.240
<v Speaker 1>All right, So let's put Kelly on Mars. She and

0:34:01.240 --> 0:34:04.160
<v Speaker 1>her cute babies in their baby spacesuits, and her and

0:34:04.200 --> 0:34:07.160
<v Speaker 1>the girl Scout troop are camping up there on Mars awesome.

0:34:07.240 --> 0:34:09.440
<v Speaker 1>And every day I wake up and my job is

0:34:09.480 --> 0:34:11.960
<v Speaker 1>to text you about whether the Earth exploded. So the

0:34:12.040 --> 0:34:13.920
<v Speaker 1>day that you get a text that the Earth exploded,

0:34:14.239 --> 0:34:17.279
<v Speaker 1>that's big news. Why because it was unlikely and so

0:34:17.320 --> 0:34:19.920
<v Speaker 1>the fact that it happened is a lot of information.

0:34:20.600 --> 0:34:21.360
<v Speaker 2>Major bummer.

0:34:22.520 --> 0:34:24.560
<v Speaker 1>So This is fascinating because it means a bits of

0:34:24.600 --> 0:34:26.600
<v Speaker 1>information like did the Earth explode?

0:34:26.680 --> 0:34:27.080
<v Speaker 3>Yes and no.

0:34:27.239 --> 0:34:29.600
<v Speaker 1>It feels like one bit like either value should be

0:34:29.680 --> 0:34:33.080
<v Speaker 1>equal amounts of information, but they're not because information depends

0:34:33.200 --> 0:34:36.760
<v Speaker 1>on context, so bits of information are not created equally.

0:34:37.200 --> 0:34:40.600
<v Speaker 1>And so Shannon said, let's define the amount of information

0:34:41.200 --> 0:34:45.120
<v Speaker 1>to be the inverse of the probability for that to happen. Right,

0:34:45.160 --> 0:34:47.640
<v Speaker 1>so if a high probability of it happens, one over

0:34:47.680 --> 0:34:49.640
<v Speaker 1>that number is a small number, so it's a small

0:34:49.680 --> 0:34:52.920
<v Speaker 1>amount of information. And if a very unlikely thing happened,

0:34:52.920 --> 0:34:55.360
<v Speaker 1>then one over that number is a very big number,

0:34:55.560 --> 0:34:59.080
<v Speaker 1>so that's a lot of information. And he called this surprisal.

0:34:59.239 --> 0:34:59.680
<v Speaker 2>That's cute.

0:34:59.719 --> 0:35:01.600
<v Speaker 1>And to make it well, behave we have the logarithm

0:35:01.640 --> 0:35:05.359
<v Speaker 1>of it. So he defines information as log of one

0:35:05.480 --> 0:35:08.440
<v Speaker 1>over the probability for something to happen, which just means

0:35:08.520 --> 0:35:12.880
<v Speaker 1>that like more probable, lower information, less probable, more information.

0:35:13.320 --> 0:35:15.759
<v Speaker 1>So now we have like a definition of information. And

0:35:15.800 --> 0:35:18.680
<v Speaker 1>again this is just something Claude Shannon made up, but

0:35:18.719 --> 0:35:21.480
<v Speaker 1>we're gonna see in a moment that actually connects with

0:35:21.800 --> 0:35:23.120
<v Speaker 1>other concepts in physics.

0:35:23.600 --> 0:35:27.560
<v Speaker 2>Would you be like taking the expected value of surprisal

0:35:27.600 --> 0:35:29.920
<v Speaker 2>after accounting for the fact that people might differ in

0:35:29.960 --> 0:35:32.920
<v Speaker 2>how surprised they are about some like would you have

0:35:33.000 --> 0:35:36.399
<v Speaker 2>to average different people's surprisal to really get a good

0:35:36.480 --> 0:35:37.840
<v Speaker 2>sense of the information.

0:35:38.200 --> 0:35:38.960
<v Speaker 3>That's really cool.

0:35:39.040 --> 0:35:41.120
<v Speaker 1>Yeah, so something might be information to me but not

0:35:41.200 --> 0:35:43.839
<v Speaker 1>to you, right Like, what if I'm the one who

0:35:43.880 --> 0:35:46.000
<v Speaker 1>destroyed the earth and then somebody texts me like the

0:35:46.080 --> 0:35:48.000
<v Speaker 1>earth blew up today, I'm like, yeah, dude, I know.

0:35:49.800 --> 0:35:52.800
<v Speaker 1>Then that's not information to me because I already knew happened,

0:35:52.800 --> 0:35:54.759
<v Speaker 1>but it is information to you. And that kind of

0:35:54.800 --> 0:35:56.840
<v Speaker 1>makes sense, right, Like, the same bit is not the

0:35:56.840 --> 0:35:58.960
<v Speaker 1>same amount of information for everybody, depending on what they

0:35:59.000 --> 0:36:02.320
<v Speaker 1>already knew. God, But there is a concept of expected

0:36:02.360 --> 0:36:05.600
<v Speaker 1>a surprisal. So if you take the kind of surprise

0:36:05.640 --> 0:36:07.719
<v Speaker 1>you might get from all the different messages you might

0:36:07.760 --> 0:36:10.359
<v Speaker 1>get from Daniel, and you average them over how likely

0:36:10.400 --> 0:36:13.279
<v Speaker 1>you are to get those messages, you get this other formula.

0:36:13.360 --> 0:36:16.120
<v Speaker 1>And this formula is fascinating because it looks just like

0:36:16.480 --> 0:36:19.880
<v Speaker 1>the formula we have in physics for calculating entropy.

0:36:20.560 --> 0:36:21.719
<v Speaker 3>Remember a few.

0:36:21.520 --> 0:36:24.520
<v Speaker 1>Episodes ago, we talked about what does entropy mean? And

0:36:24.560 --> 0:36:27.640
<v Speaker 1>we said that entropy was a ratio between basically how

0:36:27.719 --> 0:36:29.960
<v Speaker 1>much you know and how much you don't know. How

0:36:30.000 --> 0:36:32.360
<v Speaker 1>many ways can you configure the micro states of a

0:36:32.400 --> 0:36:35.320
<v Speaker 1>system to be consistent with the macro state you see,

0:36:35.520 --> 0:36:37.520
<v Speaker 1>So you see that there's particles in a box at

0:36:37.560 --> 0:36:39.880
<v Speaker 1>a certain temperature. How many ways can you arrange the

0:36:39.880 --> 0:36:43.680
<v Speaker 1>particles inside? How many different configurations can there be that

0:36:43.760 --> 0:36:46.680
<v Speaker 1>are consistent with the measurement that you made. And the

0:36:46.719 --> 0:36:49.000
<v Speaker 1>relationship between the micro states and the macro states is

0:36:49.040 --> 0:36:52.040
<v Speaker 1>also related by the formula with exactly the same structure

0:36:52.400 --> 0:36:57.000
<v Speaker 1>as Shannon's formula for average surprisal. So Shannon showed this

0:36:57.120 --> 0:37:00.319
<v Speaker 1>formula to John von Neumann, famous physicist and mathematics, and

0:37:00.360 --> 0:37:03.799
<v Speaker 1>he said, oh, you should call this information entropy for

0:37:03.880 --> 0:37:06.719
<v Speaker 1>two reasons. One because the formula looks the same. It

0:37:06.719 --> 0:37:08.960
<v Speaker 1>looks like the formula for entropy, and it's conceptually sort

0:37:09.000 --> 0:37:12.680
<v Speaker 1>of similar. And two because nobody really knows what entropy means,

0:37:12.719 --> 0:37:13.880
<v Speaker 1>and so they can't argue with you.

0:37:15.680 --> 0:37:19.080
<v Speaker 2>I like that anything that makes it impossible for people

0:37:19.080 --> 0:37:22.440
<v Speaker 2>to argue with me, I'm down for exactly.

0:37:22.520 --> 0:37:28.200
<v Speaker 1>And so in Shannon's information entropy, low information means low entropy.

0:37:28.600 --> 0:37:30.600
<v Speaker 1>So if you're getting a bunch of signals from Earth,

0:37:30.920 --> 0:37:34.279
<v Speaker 1>and you're always getting the same high probability message, like

0:37:34.360 --> 0:37:36.680
<v Speaker 1>the Earth didn't explode today, The Earth didn't explode today.

0:37:37.000 --> 0:37:40.400
<v Speaker 1>That's low information entropy. You're always getting the same one.

0:37:40.560 --> 0:37:43.040
<v Speaker 1>But if you're always getting a different message, like maybe

0:37:43.080 --> 0:37:45.640
<v Speaker 1>instead of getting texts from Daniel about whether the Earth exploded,

0:37:45.880 --> 0:37:49.759
<v Speaker 1>you're getting pictures from probes that landed on exoplanets, And

0:37:49.840 --> 0:37:51.480
<v Speaker 1>every time you open one of those, you're like, I

0:37:51.480 --> 0:37:54.080
<v Speaker 1>have no idea what to expect. Anything I see is

0:37:54.120 --> 0:37:56.480
<v Speaker 1>going to be new to me, right, and like this

0:37:56.520 --> 0:37:58.600
<v Speaker 1>one has rocks, and that one has like lava, and

0:37:58.640 --> 0:38:00.520
<v Speaker 1>that one has aliens on it, and like what is

0:38:00.640 --> 0:38:02.799
<v Speaker 1>this over here? Oh my gosh, the way like every

0:38:02.800 --> 0:38:04.680
<v Speaker 1>time we turn on a new telescope we see something

0:38:04.760 --> 0:38:08.200
<v Speaker 1>weird and surprising in the universe. Right, that's very high

0:38:08.200 --> 0:38:12.399
<v Speaker 1>information content because there's lots of different possible outcomes, each

0:38:12.480 --> 0:38:15.400
<v Speaker 1>of which are equally likely, instead of there being like

0:38:15.520 --> 0:38:19.240
<v Speaker 1>one very likely outcome. So that's high information entropy.

0:38:19.560 --> 0:38:21.920
<v Speaker 2>Okay, so now let's try to connect to mass. So

0:38:21.960 --> 0:38:25.680
<v Speaker 2>I'm wondering if an internet made of cat memes, which

0:38:25.680 --> 0:38:29.719
<v Speaker 2>would be low information, would weigh less than an Internet

0:38:29.800 --> 0:38:33.200
<v Speaker 2>that reconciles relativity with quantum mechanics, which would be a

0:38:33.239 --> 0:38:36.839
<v Speaker 2>high information internet. How do you compare those?

0:38:38.440 --> 0:38:41.759
<v Speaker 1>Yeah, so now we have a definition of information, right,

0:38:42.120 --> 0:38:44.200
<v Speaker 1>we know how to measure information into something that's low

0:38:44.200 --> 0:38:45.320
<v Speaker 1>information or high information.

0:38:45.440 --> 0:38:46.000
<v Speaker 3>And you're right.

0:38:46.160 --> 0:38:47.640
<v Speaker 1>If you get on the Internet and you see the

0:38:47.640 --> 0:38:50.000
<v Speaker 1>same cat memes you're always seeing, then that's low information.

0:38:50.520 --> 0:38:52.840
<v Speaker 1>If somebody says something really new and clever and surprise

0:38:52.880 --> 0:38:55.879
<v Speaker 1>and you're like, whoa, my gosh, that's high information. That's

0:38:55.920 --> 0:38:58.759
<v Speaker 1>more entropy. And we're talking about in terms of entropy

0:38:58.880 --> 0:39:01.040
<v Speaker 1>because we're trying to get a graph on the physical

0:39:01.160 --> 0:39:03.160
<v Speaker 1>nature of this and the consequences for it.

0:39:03.200 --> 0:39:04.360
<v Speaker 3>Like does it have mass?

0:39:04.719 --> 0:39:07.840
<v Speaker 1>Because we know entropy is connected to energy, right, and

0:39:08.000 --> 0:39:10.799
<v Speaker 1>energy is connected to mass. So can we somehow draw

0:39:10.840 --> 0:39:14.239
<v Speaker 1>a dotted line between information, cat memes and the weight

0:39:14.320 --> 0:39:20.520
<v Speaker 1>of the Internet. No, unfortunately not, because increasing the information

0:39:20.600 --> 0:39:23.560
<v Speaker 1>doesn't increase the mass or the energy of the system.

0:39:23.760 --> 0:39:26.440
<v Speaker 1>The information content is relative to what you already know,

0:39:26.600 --> 0:39:29.560
<v Speaker 1>depends on the context. You can arrange a set of

0:39:29.600 --> 0:39:31.919
<v Speaker 1>sticks or bits on the hard drive to mean one

0:39:31.920 --> 0:39:34.800
<v Speaker 1>thing or another. It doesn't change the mass or the energy.

0:39:35.000 --> 0:39:36.480
<v Speaker 1>So it has to do with how you interpret the

0:39:36.560 --> 0:39:39.680
<v Speaker 1>arrangement of the system and what you already know. It

0:39:39.719 --> 0:39:43.080
<v Speaker 1>does require some mass and some energy to store that information.

0:39:43.600 --> 0:39:45.279
<v Speaker 1>You want to put bits on a hard drive, you

0:39:45.320 --> 0:39:47.360
<v Speaker 1>want to write numbers in the sahara and filled them

0:39:47.400 --> 0:39:50.919
<v Speaker 1>with kerosene. That definitely costs energy, right, And all stored

0:39:51.040 --> 0:39:55.000
<v Speaker 1>energy does have some mass, But increasing the information on

0:39:55.040 --> 0:39:58.680
<v Speaker 1>something doesn't increase its mass. So connecting back to Mark's question,

0:39:58.960 --> 0:40:01.279
<v Speaker 1>he's asking does data have mass? And data does not

0:40:01.360 --> 0:40:03.680
<v Speaker 1>have mass? Right, And remember that when you're putting a

0:40:03.719 --> 0:40:06.080
<v Speaker 1>picture of your dog onto the SD card, you're not

0:40:06.120 --> 0:40:08.719
<v Speaker 1>like downloading electrons and not flowing onto there. You're just

0:40:08.800 --> 0:40:12.000
<v Speaker 1>moving electrons up or down. You're just flipping switches on

0:40:12.120 --> 0:40:14.600
<v Speaker 1>that card, so you're not adding matter to it in

0:40:14.640 --> 0:40:17.200
<v Speaker 1>any way. You're not changing the energy of the card.

0:40:17.440 --> 0:40:20.200
<v Speaker 1>You're just flipping a switch, which doesn't require any more

0:40:20.280 --> 0:40:22.719
<v Speaker 1>or less energy. It requires energy to build a card,

0:40:22.960 --> 0:40:25.520
<v Speaker 1>and it requires energy to change things on the card.

0:40:25.760 --> 0:40:27.440
<v Speaker 1>But the card is not heavier because you put a

0:40:27.440 --> 0:40:29.600
<v Speaker 1>picture of a dog rather than a picture of the

0:40:29.600 --> 0:40:32.239
<v Speaker 1>Earth or a picture of an exoplanet, or like the

0:40:32.239 --> 0:40:35.120
<v Speaker 1>equations of quantum gravity, which wuld be very surprising that

0:40:35.200 --> 0:40:38.360
<v Speaker 1>anybody to find have a lot of information but wouldn't

0:40:38.360 --> 0:40:41.080
<v Speaker 1>have any more mass than any other arrangement of those

0:40:41.120 --> 0:40:45.160
<v Speaker 1>electrons or bits or sticks or flaming letters in.

0:40:45.120 --> 0:40:46.440
<v Speaker 3>The Sahara course lots.

0:40:46.560 --> 0:40:50.000
<v Speaker 1>But there is one other fascinating connection between information and

0:40:50.200 --> 0:40:53.000
<v Speaker 1>mass which people may have heard about. It's called the

0:40:53.040 --> 0:40:57.120
<v Speaker 1>beckensteam bound, which talks about the amount of information you

0:40:57.160 --> 0:41:00.200
<v Speaker 1>can have in a space, because it turns out there

0:41:00.239 --> 0:41:02.799
<v Speaker 1>is a limit to how much information you can put

0:41:02.840 --> 0:41:05.560
<v Speaker 1>in a volume of space, and it turns out that's

0:41:05.560 --> 0:41:09.440
<v Speaker 1>a black hole. Right, The most information dense arrangement of

0:41:09.560 --> 0:41:13.120
<v Speaker 1>matter or energy is a black hole. So black holes

0:41:13.120 --> 0:41:17.160
<v Speaker 1>have the maximum amount of information. It's called the Beckenstein bound.

0:41:17.239 --> 0:41:20.040
<v Speaker 1>Beckenstein is a student who work with Stephen Hawking. Doesn't

0:41:20.040 --> 0:41:22.680
<v Speaker 1>get enough credit for hawking radiation and all the black

0:41:22.680 --> 0:41:26.399
<v Speaker 1>hole work that he did with Hawking, but super genius guy. Now,

0:41:26.400 --> 0:41:28.960
<v Speaker 1>this doesn't mean, as you often hear in popular science,

0:41:29.200 --> 0:41:31.960
<v Speaker 1>that if you have too much information something will collapse

0:41:31.960 --> 0:41:35.040
<v Speaker 1>into a black hole. Like if you download enough amazing

0:41:35.120 --> 0:41:37.359
<v Speaker 1>pictures of dogs under your computer, it's going to turn

0:41:37.400 --> 0:41:40.280
<v Speaker 1>into a black hole. That's not the problem. It means

0:41:40.320 --> 0:41:43.280
<v Speaker 1>that if you need to store a huge amount of information,

0:41:43.760 --> 0:41:45.520
<v Speaker 1>the only way to do it is a black hole.

0:41:45.560 --> 0:41:49.080
<v Speaker 1>A black hole is like the most information dense system

0:41:49.160 --> 0:41:49.680
<v Speaker 1>you can have.

0:41:49.840 --> 0:41:50.640
<v Speaker 3>So if you need to.

0:41:50.600 --> 0:41:53.279
<v Speaker 1>Increase the amount of information you're storing, you might need

0:41:53.320 --> 0:41:55.759
<v Speaker 1>to increase the mass of your system so much so

0:41:55.840 --> 0:41:57.080
<v Speaker 1>that you get a black hole.

0:41:57.520 --> 0:41:59.960
<v Speaker 2>Well, you know, DNA is also supposed to be very

0:42:00.080 --> 0:42:02.160
<v Speaker 2>information dents, and there are people who are arguing that

0:42:02.200 --> 0:42:05.440
<v Speaker 2>when we can easily print DNA sequences, we might want

0:42:05.440 --> 0:42:08.680
<v Speaker 2>to start storing data in DNA and sticking it in freezers.

0:42:09.080 --> 0:42:12.279
<v Speaker 2>That sounds complicated to me, but we'll see what the

0:42:12.280 --> 0:42:12.880
<v Speaker 2>future holds.

0:42:12.960 --> 0:42:15.160
<v Speaker 1>Yeah, but DNA is an amazing storage system because it

0:42:15.239 --> 0:42:17.440
<v Speaker 1>lasts for a long long time compared to hard drives.

0:42:17.680 --> 0:42:19.319
<v Speaker 1>You put something on a hard drive, you think, oh,

0:42:19.320 --> 0:42:21.440
<v Speaker 1>it's there, but five years later you come back, it

0:42:21.480 --> 0:42:24.640
<v Speaker 1>could be totally degraded. So if you have like really

0:42:24.760 --> 0:42:27.040
<v Speaker 1>valuable information the secrets to quantum gravity are on a

0:42:27.120 --> 0:42:30.080
<v Speaker 1>hard drive in your closet, make sure you're upgrading those

0:42:30.160 --> 0:42:32.360
<v Speaker 1>every couple of years because that stuff fades.

0:42:32.640 --> 0:42:35.480
<v Speaker 2>You are making me very nervous about the videos from

0:42:35.480 --> 0:42:37.640
<v Speaker 2>my PhD that are still sitting in the closet a

0:42:37.640 --> 0:42:40.279
<v Speaker 2>decade on that need to be analystt We.

0:42:40.239 --> 0:42:42.719
<v Speaker 1>Have a real problem with digital storage. People think it's

0:42:42.719 --> 0:42:44.960
<v Speaker 1>forever because it's ones and zeros, but it's not, and

0:42:45.040 --> 0:42:47.319
<v Speaker 1>actually a lot of the old analog systems we have

0:42:47.719 --> 0:42:51.360
<v Speaker 1>last longer. Like my favorite story is computer punch cards.

0:42:51.719 --> 0:42:54.399
<v Speaker 1>My dad did his graduate thesis on the computer using

0:42:54.400 --> 0:42:56.520
<v Speaker 1>punch cards. I remember being in the computer room as

0:42:56.520 --> 0:42:58.239
<v Speaker 1>he would like insert them and pick them up.

0:42:58.280 --> 0:43:00.840
<v Speaker 3>And the cool thing about punch cards is totally resilient.

0:43:00.880 --> 0:43:04.480
<v Speaker 1>They'll last a long long time, right, yea, So he

0:43:04.560 --> 0:43:06.799
<v Speaker 1>still has like stacks of punch cards that you could

0:43:06.800 --> 0:43:09.560
<v Speaker 1>still run if the computer was around. But nobody has

0:43:09.560 --> 0:43:12.400
<v Speaker 1>a hard drive from like nineteen eighty four that still works.

0:43:12.840 --> 0:43:15.399
<v Speaker 1>So back up all your stuff, folks, and don't create

0:43:15.440 --> 0:43:17.880
<v Speaker 1>black holes. The Mark, you can keep adding pictures of

0:43:17.920 --> 0:43:20.400
<v Speaker 1>your dog to your SD card without making it heavier.

0:43:21.000 --> 0:43:23.320
<v Speaker 1>So let's check in with Mark see if that answered

0:43:23.320 --> 0:43:23.880
<v Speaker 1>his question.

0:43:24.360 --> 0:43:27.719
<v Speaker 10>Thanks for answering my question, guys. I think I'm fundamentally

0:43:27.760 --> 0:43:30.919
<v Speaker 10>more enlightened now. I found it interesting how the view

0:43:30.960 --> 0:43:35.400
<v Speaker 10>on data and mass extended into information value and information

0:43:35.640 --> 0:43:40.560
<v Speaker 10>entropy and also information density. Pops Bekenstein can have a

0:43:40.600 --> 0:43:46.240
<v Speaker 10>side hustle selling high density branded SD codes. Anyway, Thanks

0:43:46.280 --> 0:43:48.080
<v Speaker 10>again and keep up with the good work.

0:43:48.520 --> 0:43:50.960
<v Speaker 2>All right, everyone, thanks for listening today. If you have

0:43:51.040 --> 0:43:52.960
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0:43:53.000 --> 0:43:55.840
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