WEBVTT - Pfizer Fights to Keep Their Vaccine Recipe Secret

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<v Speaker 1>It's Monday, November. I'm Oscar Ramirez from the Daily Dive

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<v Speaker 1>podcast in Los Angeles, and this is Reopening America. Fiser

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<v Speaker 1>recently struck a licensing deal with the Medical Patents Pool,

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<v Speaker 1>which in turn construct deals with other manufacturers to make

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<v Speaker 1>generic versions of its COVID anti viral pill for poorer countries.

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<v Speaker 1>But when it comes to its m R and A vaccine,

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<v Speaker 1>Fiser has not been so willing to share the recipe.

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<v Speaker 1>They stand to make thirty six billion dollars in revenue

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<v Speaker 1>this year and have said that they will increase their

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<v Speaker 1>shipments to poor countries at adjusted prices. Stephanie Baker, senior

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<v Speaker 1>writer at Bloomberg News, joins us for the fight over

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<v Speaker 1>profits and the lopsided global supply of vaccines. Thanks for

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<v Speaker 1>joining us, Stephanie. Thank you. There's been a lot of

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<v Speaker 1>interesting news with Fiser very recently. One of the things

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<v Speaker 1>that popped out was that they just signed a deal

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<v Speaker 1>with a u N back group to allow other manufacturers

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<v Speaker 1>to make its experimental COVID nineteen pill. There's a lot

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<v Speaker 1>of hope behind this that it would bring access to

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<v Speaker 1>this medicine to a large part of the world. They're

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<v Speaker 1>gonna be working with the medicine's patent pool, which would

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<v Speaker 1>let generic drug companies produce this pill for use in

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<v Speaker 1>a bunch of different countries. Great news. On the other

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<v Speaker 1>side of things, when we talk about the actual vaccine,

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<v Speaker 1>the Fiser vaccine, the with beyond tech that they have,

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<v Speaker 1>that is a little trickier. They are holding that a

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<v Speaker 1>little closer to the chest and don't really want to

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<v Speaker 1>let others know that secret recipe and allow others to

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<v Speaker 1>manufacture the vaccine um Their stand to make thirty six

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<v Speaker 1>billion dollars off of that this year. So Stephanie tell

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<v Speaker 1>us a little bit about what we're seeing with this. Yeah,

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<v Speaker 1>it's really interesting that Fiser has decided to take this

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<v Speaker 1>different approach with its COVID pill than it's taken with

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<v Speaker 1>the vaccine. You know, we've seen from the past year.

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<v Speaker 1>Ever since they read out their results from their COVID

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<v Speaker 1>vaccine trial, they have kept a tight grip on the

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<v Speaker 1>vaccine manufacturing process, keeping most of it in house through

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<v Speaker 1>facilities and their factories in uh the United States as

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<v Speaker 1>well as in Belgium, and they really resisted calls to

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<v Speaker 1>either do licensed manufacturing deals with other vaccine manufacturers around

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<v Speaker 1>the world. Particularly in low income countries like Africa or Asia,

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<v Speaker 1>and they have opposed this proposal at the World Trade

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<v Speaker 1>Organization to waive intellectual property protections on COVID vaccines and therapeutics,

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<v Speaker 1>and you know, they really just sort of resisted all

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<v Speaker 1>the calls to either share the technology or just do

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<v Speaker 1>more license manufacturing deals with a wider array of producers.

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<v Speaker 1>So I think you might conclude by that that they

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<v Speaker 1>perhaps have learned their lesson from the past year that

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<v Speaker 1>they need to be more inclusive and perhaps have decided

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<v Speaker 1>to take a different approach with the covid pill. Now,

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<v Speaker 1>it could be that the covid pill is potentially easier

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<v Speaker 1>to produce. Vaccines are very complicated. There's something like two

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<v Speaker 1>d and eighty six compos oonents from nineteen countries that

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<v Speaker 1>go into the covid vaccine that Fiser and its German

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<v Speaker 1>partner by in Tech make. I think the covid pill

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<v Speaker 1>is probably a simpler product to outsourced two generic producers.

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<v Speaker 1>That may be one factor at play. Yeah, and until now,

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<v Speaker 1>you know, we we always knew was going to be

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<v Speaker 1>that race to buy up as many doses as you can,

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<v Speaker 1>and we saw that with very much with all the

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<v Speaker 1>higher income countries, and that's exactly how it played out

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<v Speaker 1>for pretty much every vaccine they FISER, for their part,

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<v Speaker 1>has started to make more shipments supporter countries, but they're

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<v Speaker 1>really in dire need of more doses that I think

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<v Speaker 1>from the article. You know, Africa only six percent of

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<v Speaker 1>the people that are fully inoculated as of early November.

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<v Speaker 1>I mean, that's almost nothing right there. So I know

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<v Speaker 1>FISER is starting to increase those shipments, but that's why

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<v Speaker 1>people are asking for, you know, the a waiver of

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<v Speaker 1>the intellectual property. Maybe they can start manufacturing in different places.

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<v Speaker 1>I know they were trying to set up a hub

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<v Speaker 1>in Africa as well, just to help with all of this,

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<v Speaker 1>right the medicine's patent. The group, the u N back

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<v Speaker 1>group that that FISER says it will cooperate with on

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<v Speaker 1>the COVID pill. They're sponsoring this m rn A vaccine

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<v Speaker 1>manufacturing hub in South Africa, but haven't gotten much feedback

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<v Speaker 1>from any of the m RNA producers on that. So yeah,

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<v Speaker 1>there's this huge push to try to get more vaccines out.

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<v Speaker 1>I mean, FISER did this big deal with the US

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<v Speaker 1>government after a huge amount of pressure on them to

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<v Speaker 1>do more, including the US backing this i P waiver

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<v Speaker 1>proposal at the w t O, which really shocked the

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<v Speaker 1>world that the US, a staunch supporter of intellectual property protections,

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<v Speaker 1>would back something like that. It was a real gut

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<v Speaker 1>punch to the pharmaceutical industry. So after that, Fiser did

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<v Speaker 1>this big deal for a billion doses, selling those at

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<v Speaker 1>cost to the U S Government, and the U S

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<v Speaker 1>Government would in turn turn around and donate those two

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<v Speaker 1>low and middle income countries. But however, only about two

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<v Speaker 1>million of those donated doses will ship by the end

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<v Speaker 1>of this year, so the vast majority of that supply

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<v Speaker 1>will only arrive the middle of next year, possibly towards

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<v Speaker 1>the end. You know, the production is very much prioritized

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<v Speaker 1>to paying customers, mostly in wealthy countries who are rolling

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<v Speaker 1>out these booster campaigns. And that's an interesting part of

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<v Speaker 1>it too, because their CEO basically was talking about how

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<v Speaker 1>they sell this, and they say that they do sell

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<v Speaker 1>it on a sliding scale, right, so higher income countries

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<v Speaker 1>get it at one price, they slash that price a

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<v Speaker 1>little bit more for middle income countries, and for poorer countries,

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<v Speaker 1>they're basically selling it at cost. And part of their

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<v Speaker 1>argument for fiser. They say, well, let's say we do

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<v Speaker 1>give up the I P. What let's say we do

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<v Speaker 1>let other people manufactured. For them to ramp up any

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<v Speaker 1>type of production is going to take them a year

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<v Speaker 1>to eighteen months to do all of that. In the meantime,

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<v Speaker 1>they're saying, we're manufacturing this at a at a fast pace,

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<v Speaker 1>We're going to meet all those numbers by that time. Anyways,

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<v Speaker 1>part of me does agree with that, and I see

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<v Speaker 1>the point that it's it's we're pretty late in the

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<v Speaker 1>game at this point to be trying to start up

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<v Speaker 1>new manufacturing sites that will make a dent in the pandemic.

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<v Speaker 1>As it stands now, it will take maybe not eighteen months. Look,

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<v Speaker 1>Fighter stood up its own manufacturing capacity much more quickly,

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<v Speaker 1>you know, within nine months, um. It possibly even shorter.

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<v Speaker 1>And they know a lot more about the manufacturing process

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<v Speaker 1>now than they did a year ago. So we're in

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<v Speaker 1>a different world now. And the real question is we

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<v Speaker 1>don't know if we're going to the world is going

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<v Speaker 1>to need an annual booster shot. We just don't know

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<v Speaker 1>at this point, So we could be constantly playing catch

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<v Speaker 1>up of needing seven billion doses potentially a year to

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<v Speaker 1>try to get the vast majority of the population with

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<v Speaker 1>immunity to keep the pandemic at bay, and and and

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<v Speaker 1>push it towards an endemic virus that is still there

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<v Speaker 1>but not shutting down economies. Yeah, and that's an interesting

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<v Speaker 1>what you're right, We don't know right now, but it

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<v Speaker 1>seems like it's heading that way. We've seen studies saying

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<v Speaker 1>that the effectiveness of the vaccine of all of them,

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<v Speaker 1>really start waning after a period of time, so you know,

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<v Speaker 1>the need for boosters might be a more commonplace thing.

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<v Speaker 1>One of the interesting things too, that you wrote about

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<v Speaker 1>is just making contracts with other countries and Fightser asking

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<v Speaker 1>for you know, the waving of certain liabilities and all that.

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<v Speaker 1>Can you talk to the speak to that a little bit,

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<v Speaker 1>because that was really interesting. It said that in some

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<v Speaker 1>cases deals are starting to fall apart because of that. Yeah.

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<v Speaker 1>This was really fascinating and incredibly difficult to report out.

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<v Speaker 1>It was so secretive. Fighter asked for nondisclosure agreements confidentiality

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<v Speaker 1>agreements with all the countries that it was doing manufacturing

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<v Speaker 1>deals with, so some of the contracts leaked out. We

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<v Speaker 1>got reports from some of the countries that were upset

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<v Speaker 1>with viser's demands for complete indemnity. You know, they wanted

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<v Speaker 1>protection against all liabilities associated with the vaccine, including negligence,

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<v Speaker 1>which some for some countries that felt like a step

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<v Speaker 1>too far. Now you're dealing with legal systems in different

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<v Speaker 1>countries that vary widely, so how do you interpret what

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<v Speaker 1>quote unquote negligence means. But you know, they did not

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<v Speaker 1>want to be held liable for mistakes made in the

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<v Speaker 1>manufacturing process or doses that perhaps spoiled along the way.

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<v Speaker 1>And to some extent, you can understand that they're rushing.

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<v Speaker 1>We're in the middle of a pandemic. It's a it's

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<v Speaker 1>an emergency. You don't want to necessarily have pharmaceutical companies

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<v Speaker 1>not step up to the plate because they're worried that

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<v Speaker 1>they might be held liable because they're rushing, and you know,

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<v Speaker 1>mistakes do happen. But this did hold up negotiations in

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<v Speaker 1>a number of countries South Africa, Argentina, Brazil, you know

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<v Speaker 1>who pushed back on the kind of demands that fires

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<v Speaker 1>are made, including in some cases they were asking to

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<v Speaker 1>put up collateral. How are you going to pay for

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<v Speaker 1>us and pay for any claims related to the vaccine

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<v Speaker 1>if something should go wrong. That includes you know, adverse

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<v Speaker 1>events from you know, individuals who we know the vaccines

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<v Speaker 1>are very safe, but there are occasionally in cases where

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<v Speaker 1>you know, if someone reacts badly, and there there's compensation

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<v Speaker 1>programs set up in the United States to deal with that.

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<v Speaker 1>They wanted to replicate those kind of protections worldwide, and

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<v Speaker 1>most countries didn't have a system set up for that,

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<v Speaker 1>a sort of vaccine compensation scheme, and that's what they

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<v Speaker 1>were trying to replicate. So they had huge sway over

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<v Speaker 1>you know, new laws being written in these countries to

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<v Speaker 1>set up these sort of schemes, and you know that

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<v Speaker 1>that caused delays. We're talking about Fiser and you know

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<v Speaker 1>they've had nothing but first and a lot of this.

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<v Speaker 1>You can call them probably the the global front and

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<v Speaker 1>runner in this COVID vaccine race. How have other vaccine

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<v Speaker 1>makers fared in all this and sharing this and you

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<v Speaker 1>know what we're talking about getting as many people across

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<v Speaker 1>the world now access to these vaccines. Maderna Johnson and Johnson,

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<v Speaker 1>astros Eneka some other big players in this. How have

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<v Speaker 1>they fared with all this and trying to share their

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<v Speaker 1>recipes for this? Right? So, Maderna, for On, a small

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<v Speaker 1>biotech company that had never produced a license drug before

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<v Speaker 1>and you know, produced this fantastic mRNA vaccine. But they

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<v Speaker 1>employed about a thousand people. There are tiny company that is. Um.

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<v Speaker 1>It was kind of incredible that they stood up the

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<v Speaker 1>amount of manufacturing that they did given how small they are.

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<v Speaker 1>They were aiming for a billion doses by the end

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<v Speaker 1>of this year. So far they supplied a little over

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<v Speaker 1>fifty million. I believe off the top of my head,

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<v Speaker 1>I think they may fall slightly short of their target

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<v Speaker 1>of a billion doses by the end of the year.

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<v Speaker 1>And you know, they when this w t O proposal

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<v Speaker 1>to wave IP rights came up, they said, look, we're

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<v Speaker 1>not going to enforce our our patents. UM. During the pandemic,

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<v Speaker 1>they were sort of a bit hands off. It was,

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<v Speaker 1>you know, it's hard to replicate these vaccines, so that

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<v Speaker 1>was an easy thing to say. But um, you know,

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<v Speaker 1>and they were charging quite high prices. On the flip side,

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<v Speaker 1>you have astras Enka, which promised their vaccine would be

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<v Speaker 1>not for profit for the world and did these licence

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<v Speaker 1>manufacturing deals, including with the world's largest vaccine manufacturer in India.

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<v Speaker 1>The ceremon Institute, and the vast majority of their doses

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<v Speaker 1>they've produced about the same amount as fies are two billions,

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<v Speaker 1>just over two billion. Vast majority of their doses have

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<v Speaker 1>gone to low and middle income countries. A lot of

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<v Speaker 1>big chunk of that is because of India, which threw

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<v Speaker 1>up it's the gates and refused to allow the vaccines

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<v Speaker 1>produced in India to leave the country, as you were called.

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<v Speaker 1>They had a terrible time with the pandemic with a

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<v Speaker 1>wave of COVID deaths, and then they've recently said that

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<v Speaker 1>they will start charging a bit more to high income countries.

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<v Speaker 1>They've abandoned that that not for profit pledge, which was

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<v Speaker 1>a sad but probably inevitable move given that they had

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<v Speaker 1>given had so many problems with the vaccine rollout and

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<v Speaker 1>gotten such bad press on for a number of different reasons. Yeah,

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<v Speaker 1>and as they mentioned, you know, as the pandemic does

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<v Speaker 1>turn endemic, you know this, we're going to probably see

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<v Speaker 1>a lot of this and we'll see how fiser affairs

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<v Speaker 1>and all of this. They're gonna hold it pretty close.

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<v Speaker 1>There's obviously stands to a lot of money to be made,

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<v Speaker 1>but it's very very complex. As we've been talking about,

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<v Speaker 1>so we'll see how Fiser fares with all of that.

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<v Speaker 1>Stephanie Baker, Senior writer at Bloomberg News, thank you very

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<v Speaker 1>much for joining us. Thank you. I'm Oscar Ramirez and

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<v Speaker 1>this has been reopening America. Don't forget effort today's big

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<v Speaker 1>news stories. You can check me out on the Daily

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<v Speaker 1>Dive podcast every money through Friday. So follow us in

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<v Speaker 1>I Heart radio or wherever you get your podcast