1 00:00:00,520 --> 00:00:03,600 Speaker 1: Welcome to brain Stuff from how stuff works dot com 2 00:00:03,600 --> 00:00:14,280 Speaker 1: where smart Happens. Hi, I'm Marshall Brain with today's question, 3 00:00:14,600 --> 00:00:19,480 Speaker 1: how does your stomach keep from digesting itself? Your stomach, 4 00:00:19,640 --> 00:00:21,760 Speaker 1: if you want to be technical about it, is a 5 00:00:21,840 --> 00:00:25,840 Speaker 1: crescent shaped, hollow organ about the size of a large melon. 6 00:00:26,440 --> 00:00:30,040 Speaker 1: The average adult stomach holds about three courts or three 7 00:00:30,120 --> 00:00:33,040 Speaker 1: leaders of fluid. Your stomach is made up of a 8 00:00:33,120 --> 00:00:37,600 Speaker 1: variety of layers, including the sarosa, the outer layer that 9 00:00:37,720 --> 00:00:41,000 Speaker 1: acts as a covering for the other layers, the two 10 00:00:41,120 --> 00:00:44,600 Speaker 1: muscle layers, the middle layers that propel food from the 11 00:00:44,640 --> 00:00:48,480 Speaker 1: stomach into the small intestine, and the mucosa. The inner 12 00:00:48,600 --> 00:00:53,600 Speaker 1: layer made up of specialized cells, including perietal cells, G cells, 13 00:00:53,640 --> 00:00:59,480 Speaker 1: and epithelial cells. Perietal cells produce hydrochloric acid, a strong 14 00:00:59,640 --> 00:01:03,000 Speaker 1: asked that helps to break down food. The acid in 15 00:01:03,080 --> 00:01:06,160 Speaker 1: your stomach is so concentrated that if you were to 16 00:01:06,200 --> 00:01:08,600 Speaker 1: place a drop on a piece of wood, it would 17 00:01:08,680 --> 00:01:12,480 Speaker 1: eat right through it. The G cells produce gastron, a 18 00:01:12,520 --> 00:01:16,120 Speaker 1: hormone that facilitates the production of hydrochloric acid by the 19 00:01:16,160 --> 00:01:20,880 Speaker 1: perietal cells. The stomach is protected by the epithelial cells, 20 00:01:21,200 --> 00:01:25,840 Speaker 1: which produce and secrete a bicarbonate rich solution that coats 21 00:01:25,920 --> 00:01:30,080 Speaker 1: the mucosa. By Carbonate is an alkaline a base and 22 00:01:30,200 --> 00:01:34,880 Speaker 1: neutralizes the acid secreted by the perietal cells, producing water 23 00:01:34,959 --> 00:01:39,080 Speaker 1: in the process. This continuous supply of by carbonate is 24 00:01:39,120 --> 00:01:43,679 Speaker 1: the main way that your stomach protects itself from autodigestion 25 00:01:44,160 --> 00:01:49,280 Speaker 1: or the stomach digesting itself, and from the overall acidic environment. 26 00:01:49,960 --> 00:01:53,600 Speaker 1: In some individuals, due to impairments in blood supply to 27 00:01:53,640 --> 00:01:57,520 Speaker 1: the stomach or to the overproduction of acid, this defense 28 00:01:57,560 --> 00:02:00,760 Speaker 1: system does not work as well as it should. These 29 00:02:00,800 --> 00:02:05,480 Speaker 1: people can get gastric ulcers. There are also specific bacteria 30 00:02:05,920 --> 00:02:11,360 Speaker 1: called Helicobacter pylori that may cause impairment of the stomach's 31 00:02:11,360 --> 00:02:15,959 Speaker 1: defenses and can also be responsible for ulcers. For more 32 00:02:16,000 --> 00:02:18,600 Speaker 1: on this and thousands of other topics, visit how stuff 33 00:02:18,639 --> 00:02:23,400 Speaker 1: works dot com.