WEBVTT - From the Vault: Dangerous Foods: Adverse Additives

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<v Speaker 1>Hey, Welcome to Stuff to Blow Your Mind. My name

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<v Speaker 1>is Robert Lamb and I'm Joe McCormick, and it's Saturday.

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<v Speaker 1>Time to go into the vault for a classic episode.

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<v Speaker 1>This was Let's see, was this from last year? Yeah,

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<v Speaker 1>I guess it was. This was one of our Dangerous

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<v Speaker 1>Foods episodes where we talked about Oh oh, I think

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<v Speaker 1>this is the one with killer beer in it. Yeah,

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<v Speaker 1>this one had concerned adverse additives in foods as part

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<v Speaker 1>of our long running Dangerous Food series. I don't know

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<v Speaker 1>if we're gonna if we're gonna have any anything to

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<v Speaker 1>discuss this year, if there'll be another Dangerous Foods episode,

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<v Speaker 1>or if this was essentially the finale. Yeah, I don't know.

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<v Speaker 1>We'll see what we turn up. All right, let's jump in.

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<v Speaker 1>Welcome to Stuff to Blow Your Mind production of I

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<v Speaker 1>Heart Radios Hows to work. Hey are you welcome to

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<v Speaker 1>Stuff to Blow Your Mind? My name is Robert Lamb

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<v Speaker 1>and I'm Joe McCormick in his feast time. That's right,

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<v Speaker 1>Thanksgiving season here once again and in the United States

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<v Speaker 1>at any rate. So we're continuing a tradition, a tradition

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<v Speaker 1>of dangerous foods in which we highlight foods that at

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<v Speaker 1>least can be dangerous or deadly under the right conditions.

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<v Speaker 1>I mean, we were trying not to alarm anyone, but

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<v Speaker 1>we find that there's there's a lot of a lot

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<v Speaker 1>of fun to be had in exploring the dangerous side

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<v Speaker 1>of our culinary creations and our culinary instincts right now.

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<v Speaker 1>This can range from such a strange exotic chemical adventures

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<v Speaker 1>in the past as the hallucinogenic seabream of the Mediterranean,

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<v Speaker 1>or or like toxic honey that was chronicled in the

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<v Speaker 1>ancient world as leading to victories in battle when when

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<v Speaker 1>one side ate the honey and the other could take

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<v Speaker 1>advantage of that. But it also goes into the mundane

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<v Speaker 1>world where we're just like normal food items that we

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<v Speaker 1>all take for granted. If not prepared the right way,

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<v Speaker 1>could go very bad for you. For example, normal dried beans,

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<v Speaker 1>kidney beans, and so forth. You need to boil those,

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<v Speaker 1>you don't just soak them and eat them, and if

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<v Speaker 1>you do, you can experience some some extreme gastro intestinal problems. Yeah,

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<v Speaker 1>a lot of it comes down to, Okay, here's the

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<v Speaker 1>thing that human beings can eat, but under what circumstances

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<v Speaker 1>can humans eat it? What do they have to do

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<v Speaker 1>to it first? Do they have to remove certain parts

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<v Speaker 1>of it? Are only certain parts edible? Is it only

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<v Speaker 1>in and then or those parts only edible after the

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<v Speaker 1>content has been cooked a certain way? Likewise, is there

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<v Speaker 1>a certain time during which a particular vegetable item should

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<v Speaker 1>be harvested? And is it dangerous to harvest it or

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<v Speaker 1>and or consume it at another time? Or do you

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<v Speaker 1>leave it sitting around too long? As we talked about

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<v Speaker 1>cases with potato poisonings in the past, where potatoes were

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<v Speaker 1>just left in the sack for got a little too

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<v Speaker 1>wisened and then they made some schoolboys sick in England,

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<v Speaker 1>they get that unhealthy green color, right, Yeah, But of

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<v Speaker 1>course humans don't just eat this vegetable or that invertebrate.

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<v Speaker 1>We we also combine all of these things. We add

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<v Speaker 1>a small dosage of various spices, for instance, spices which

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<v Speaker 1>in their natural form are chemical weapons and might prove

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<v Speaker 1>very uncomfortable or dangerous to consume, you know, especially if

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<v Speaker 1>you're consuming them, and a quantity beyond that that which

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<v Speaker 1>is advisable when when cooking, and the culinary palate becomes

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<v Speaker 1>quite vast. This way and out of this complexity many

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<v Speaker 1>of the most magical of culinary possibilities emerge. Yeah, I

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<v Speaker 1>was just your note here made me think about the

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<v Speaker 1>fact that, of course I love spicy food. I think

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<v Speaker 1>you like spicy food too, right, Yeah? Uh that that

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<v Speaker 1>so many of these compounds that we so desire in

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<v Speaker 1>our foods to liven them up are of course defenses there,

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<v Speaker 1>as you say, you know, their chemical weapons. That what

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<v Speaker 1>makes the garlics so hot and wonderful. It's got these

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<v Speaker 1>compounds that come together when it's sell walls or ruptured

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<v Speaker 1>and produce this pungent odor and flavor that we love.

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<v Speaker 1>But this mention of spice was also making me wonder

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<v Speaker 1>a question I don't think we've ever addressed on the

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<v Speaker 1>show before. Maybe you got into it many years ago,

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<v Speaker 1>which is can you be killed by hot peppers? You know,

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<v Speaker 1>I'm not sure we may have covered a little bit

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<v Speaker 1>of that in the past. I know we did an

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<v Speaker 1>episode on nutmeg once. It was really interesting that got

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<v Speaker 1>into a little bit of you know, the question of

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<v Speaker 1>what is a lethal dose of nutmeg? What happens when

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<v Speaker 1>you consume too much nutmeg? Um and and one of

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<v Speaker 1>the things that was really emerged in that research was that, yeah,

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<v Speaker 1>most spices, most household spices, if you consume too much

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<v Speaker 1>of it, you will hurt yourself. Right, Um, that's just

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<v Speaker 1>that's just kind of a fact no matter what you're

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<v Speaker 1>grabbing out of the spice cabinet. But with a lot

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<v Speaker 1>of these things, you would have to consume an amount

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<v Speaker 1>of it that is not a reasonable amount that would

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<v Speaker 1>ever be used in cooking, right. It would be the

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<v Speaker 1>food would become inedible, Like you would have to really

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<v Speaker 1>force yourself to choke it down. It would have to

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<v Speaker 1>be a very deliberate act. Yeah, And I think this

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<v Speaker 1>actually turns out to be the case with this question

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<v Speaker 1>about hot peppers, as a lover of spicy food and

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<v Speaker 1>as somebody who has taken a bite out of a

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<v Speaker 1>raw Carolina Reaper pepper for an on camera experiment, which

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<v Speaker 1>I mean that was a horrible experience. Is that what

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<v Speaker 1>you're calling a YouTube challenge? Is that it wasn't a

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<v Speaker 1>YouTube challenge. It was just it was just Rachel videoing

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<v Speaker 1>me with her phone. Her dad showed up at the

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<v Speaker 1>house with one of these. It was one of the

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<v Speaker 1>spiciest peppers in the world. One of you did something here,

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<v Speaker 1>No no, no, no no, it was. It was in Tennessee.

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<v Speaker 1>It was like, you know, so one of these uh

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<v Speaker 1>like ten billion Scoville units peppers. He showed up and

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<v Speaker 1>he was like, he knows I like spicy food. He's like,

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<v Speaker 1>you want to try it? So I took a bite

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<v Speaker 1>of it on camera, and yeah, that was like, I

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<v Speaker 1>love spicy food. But that became a problem. It was

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<v Speaker 1>just more like I had a disease for the rest

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<v Speaker 1>of the day. Uh. And I tried to fix it,

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<v Speaker 1>as you know, one thing you can do if you've

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<v Speaker 1>eaten too much spicy food is you can try to

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<v Speaker 1>neutralize it with some milk in your mouth. But then

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<v Speaker 1>I ended up drinking some spoiled milk, so that made

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<v Speaker 1>it even worse. It sounds like a comedy bit. The

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<v Speaker 1>comedy was all in my body. But yeah, so I

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<v Speaker 1>was wondering, well, okay, so that felt pretty bad, even

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<v Speaker 1>though I love really spicy food. Is it possible to

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<v Speaker 1>eat food so spicy it kills you? Technically yes, but

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<v Speaker 1>under practical circumstances not really. Uh. The active compound in

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<v Speaker 1>chili peppers that makes them spicy is called cap sasan.

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<v Speaker 1>Eating large amounts of capsasan can cause. Of course, you know,

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<v Speaker 1>all the symptoms were familiar with gastro intestinal distress, even vomiting, sweating, flushing, irritation,

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<v Speaker 1>and the mucous membranes and all that which those symptoms

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<v Speaker 1>themselves could potentially harm someone maybe if they're saying a

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<v Speaker 1>very sensitive cardio pulmonary state. But as for just like

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<v Speaker 1>somebody in normal health being poisoned by too much peppers. Uh,

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<v Speaker 1>I did find some cases where people had aspirated peppers,

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<v Speaker 1>and and that was dangerous. But normally you're not like

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<v Speaker 1>breathing in peppers, uh, when you're eating them, you're just

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<v Speaker 1>swallowing them. So I found one article by someone named

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<v Speaker 1>Catherine Gammon, who consulted no less an authority than Paul Bosland,

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<v Speaker 1>a professor of horticulture at New Mexico State University and

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<v Speaker 1>director of the Chili Pepper Institute. They've got this whole

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<v Speaker 1>chili pepper lab there where they like breed new strains

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<v Speaker 1>of chili's um and bosl sites of study from nineteen

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<v Speaker 1>eighty on the acute toxicity of cap sasan. So how

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<v Speaker 1>much does it take to just kill you? By his estimation,

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<v Speaker 1>the research revealed that to kill a one hundred and

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<v Speaker 1>fifty pound person with cap sasan you need to serve

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<v Speaker 1>them about three pounds of the powder form of one

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<v Speaker 1>of the spiciest peppers known to human kinds, such as

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<v Speaker 1>the boot jill Lochia or the ghost pepper. Uh. And

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<v Speaker 1>this would need to be all in one sitting. So

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<v Speaker 1>you get them to eat three pounds of the powdered

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<v Speaker 1>form all at once. Uh. And he notes that your

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<v Speaker 1>body just probably would not allow this. Some things would

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<v Speaker 1>happen to stop you on the on the course of

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<v Speaker 1>the suicide mission. Yeah. That Yeah, you would have to

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<v Speaker 1>be an act of madness to really eat that much

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<v Speaker 1>much of the pepper. Yeah. So, unless you're already in

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<v Speaker 1>very delicate health or you're doing something very unusual and extreme,

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<v Speaker 1>eating spicy food, even really really spicy food is perfectly safe.

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<v Speaker 1>But hey, that's all. That's all the organic world. Well,

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<v Speaker 1>I mean, I guess it's actually not, because we're breeding

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<v Speaker 1>these peppers hotter and hotter. That is sort of agricultural technology.

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<v Speaker 1>But still, you know this is coming from a plant,

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<v Speaker 1>right right. Yeah, So we get into this situation where

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<v Speaker 1>we're taking these plants, we're taking spices, we're taking other

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<v Speaker 1>things the vast palate of things from our natural world

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<v Speaker 1>and then using them to create food. And it's one thing.

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<v Speaker 1>If we're creating that food within the household or within

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<v Speaker 1>say a close tight knit community, uh such as you know,

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<v Speaker 1>it would have been more or less the you know,

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<v Speaker 1>the archaic normal for for humans. But of course we

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<v Speaker 1>ascend past that, right we we begin developing much larger groups,

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<v Speaker 1>and we begin specializing the creation of various things, various

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<v Speaker 1>food products, especially various technologies, and we end up engaging

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<v Speaker 1>in trade, uh and the stockpiling of foods as well.

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<v Speaker 1>So given this, you know, there's this increased complexity allows

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<v Speaker 1>us to work kind of a dark magic here as well.

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<v Speaker 1>Not only can we enhance the flavor of our ingredients,

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<v Speaker 1>but we can also hide ending smells, not nearly in

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<v Speaker 1>a you know, in a household sense, like well, this

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<v Speaker 1>fish is a little off, but we need to eat

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<v Speaker 1>it more in the this fish is bad, but I

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<v Speaker 1>really need to sell it way right. But they are

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<v Speaker 1>all kinds of tricks like that. I mean, another thing

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<v Speaker 1>you could do if you've seen one of those crime

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<v Speaker 1>movies where somebody's like they cut the dope, you know,

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<v Speaker 1>putting baby powder in the brick of heroin or whatever.

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<v Speaker 1>People do that with food products too, Yeah, and we'll

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<v Speaker 1>get into some some wonderful, wonderful examples of that. Uh yeah. Basically,

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<v Speaker 1>it opens the door for all manner of cuts and

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<v Speaker 1>shortcuts and cheets, all predicated on the fact that in

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<v Speaker 1>an industry of food, the maker doesn't have to consume

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<v Speaker 1>their own food product, right, and perhaps they'll be down

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<v Speaker 1>the road by the time somebody does. Now, So we

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<v Speaker 1>are going to be talking about food adulteration and food

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<v Speaker 1>adjectives today. But I don't want to contribute, as we

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<v Speaker 1>always do in these episodes. We don't want to contribute

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<v Speaker 1>to food panic, and I don't want to contribute to

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<v Speaker 1>additive panic. I think there are some people who have

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<v Speaker 1>this attitude like I don't allow any chemicals in my

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<v Speaker 1>food or something, which I think we've discussed that attitude

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<v Speaker 1>on the show before. It doesn't really make sense. I mean,

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<v Speaker 1>your food already has chemicals and it is native chemicals. Uh.

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<v Speaker 1>Just looking at a something with a synthetic sounding name

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<v Speaker 1>doesn't necessarily mean it's going to hurt you, right. And

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<v Speaker 1>we'll touch a little bit, very very briefly on sort

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<v Speaker 1>of the current state of additives in the in the

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<v Speaker 1>future of additives, and and just the level of like

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<v Speaker 1>legitimate concern and sometimes panic that that comes with discussion

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<v Speaker 1>of these things. But for the most part in this episode,

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<v Speaker 1>we're gonna be talking about older additives, additives that we

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<v Speaker 1>can safely say we're a bad idea, that it's not

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<v Speaker 1>a matter a matter of opinion, uh, you know, regarding

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<v Speaker 1>whether you should put this particular ingredient and say a

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<v Speaker 1>candy or not. Um. Yeah, we're and we're largely talking

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<v Speaker 1>about the deliberate adulteration of food. And this has actually

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<v Speaker 1>been with us since ancient times. Uh. There are ancient

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<v Speaker 1>laws and rules that that there that govern how we

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<v Speaker 1>handle our food, how we prepare food in order to

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<v Speaker 1>ensure food quality. This almost seems to me like it

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<v Speaker 1>would be one of the earliest concerns of civilization. You know, like,

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<v Speaker 1>once you're no longer making your own food or having

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<v Speaker 1>your own food made by a family member, your food

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<v Speaker 1>is being made by somebody maybe that you don't even know,

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<v Speaker 1>you don't even know their name, it's being made in

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<v Speaker 1>some place you can't see. You would naturally, I think,

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<v Speaker 1>have people start to worry and wonder, like what's in

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<v Speaker 1>my food? Yeah, yeah, So I was looking at a

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<v Speaker 1>source on this from on Marcia a Ecoles, who have

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<v Speaker 1>food safety the interplay of culture and science, of culture,

0:11:41.840 --> 0:11:45.640
<v Speaker 1>science and technology, and the author points out a number

0:11:45.640 --> 0:11:49.520
<v Speaker 1>of cool facts about sort of the ancient history of

0:11:49.520 --> 0:11:53.680
<v Speaker 1>of food safety. So the Assyrians established weights and measures

0:11:53.679 --> 0:11:56.920
<v Speaker 1>for grains because and we're getting this one of the

0:11:57.040 --> 0:11:59.600
<v Speaker 1>guess one key way that you can you can cheat

0:11:59.640 --> 0:12:03.120
<v Speaker 1>assus hm of weights and prices based on weights is

0:12:03.160 --> 0:12:07.440
<v Speaker 1>to put something in with your grain to weight it down. UM.

0:12:07.480 --> 0:12:10.840
<v Speaker 1>As early as two b c. E In, residents of

0:12:10.880 --> 0:12:14.880
<v Speaker 1>India punished economic adulteration of grains and oils. During the

0:12:14.920 --> 0:12:19.520
<v Speaker 1>same era, the Chinese combated consumer fraud. The ancient Athenians

0:12:19.559 --> 0:12:23.280
<v Speaker 1>had purity standards for both beer and wine. The Romans

0:12:23.280 --> 0:12:26.360
<v Speaker 1>had a system to control fraud and bad produce, and

0:12:26.400 --> 0:12:30.120
<v Speaker 1>there are various other ancient laws, religious or otherwise that's

0:12:30.160 --> 0:12:33.439
<v Speaker 1>governed the handling of meat in ways that we're concerned

0:12:33.520 --> 0:12:36.760
<v Speaker 1>ultimately with with purity, which of course is we've discussed

0:12:36.840 --> 0:12:38.840
<v Speaker 1>many times in the shows. It's a tricky concept because

0:12:38.880 --> 0:12:42.360
<v Speaker 1>in purity you're getting ideas of sort of hygiene mixed

0:12:42.440 --> 0:12:46.079
<v Speaker 1>up with with with less um a matter of fact

0:12:46.160 --> 0:12:49.280
<v Speaker 1>statements about a food. But you know, as we discussed

0:12:49.280 --> 0:12:51.800
<v Speaker 1>with pork recently on the show, there's always this argument

0:12:51.920 --> 0:12:56.120
<v Speaker 1>that the purity is at least partially grounded in health concerns. Sure,

0:12:56.559 --> 0:12:58.800
<v Speaker 1>and you can maybe make arguments like that about the

0:12:59.120 --> 0:13:02.120
<v Speaker 1>mixing of different types of foods that are forbidden in

0:13:02.160 --> 0:13:05.959
<v Speaker 1>some religious customs. Maybe not that there's actually anything wrong

0:13:06.000 --> 0:13:08.080
<v Speaker 1>with mixing those types of foods, but perhaps there was

0:13:08.080 --> 0:13:12.320
<v Speaker 1>a perception in the ancient world that it could be dangerous. Now,

0:13:12.360 --> 0:13:15.240
<v Speaker 1>another source that I was looking at here is is

0:13:15.280 --> 0:13:19.280
<v Speaker 1>a wonderful right up by Adam Burrows J. D Uh

0:13:19.320 --> 0:13:23.440
<v Speaker 1>And it's titled Palette of Our Palettes Clever. A Brief

0:13:23.480 --> 0:13:26.880
<v Speaker 1>History of Food Coloring and its Regulation from Comprehensive Reviews

0:13:26.880 --> 0:13:29.160
<v Speaker 1>and Food Science and Food Safety, And this is from

0:13:29.160 --> 0:13:32.720
<v Speaker 1>two thousand nine. Uh. Burrows points out that the ancient

0:13:32.720 --> 0:13:36.319
<v Speaker 1>Egyptians wrote of drug colorance, but archaeologists think food coloration

0:13:36.360 --> 0:13:42.040
<v Speaker 1>itself dates back to roughly c. Saffron, for example, is

0:13:42.040 --> 0:13:45.079
<v Speaker 1>mentioned in the Iliad, and plenty of the Elder wrote

0:13:45.080 --> 0:13:48.760
<v Speaker 1>of colored wines and four hundred b C. And I

0:13:48.800 --> 0:13:50.600
<v Speaker 1>looked into this little more and it seems like he's

0:13:50.600 --> 0:13:53.400
<v Speaker 1>possibly talking about the use of squid inc uh in

0:13:53.720 --> 0:13:55.480
<v Speaker 1>the wind. I guess, you know, give dark in it

0:13:55.480 --> 0:13:58.440
<v Speaker 1>and may give it this thicker appearance. Squid inc is

0:13:58.480 --> 0:14:01.840
<v Speaker 1>still used as a food additive today. Yeah. Yeah, Like

0:14:01.880 --> 0:14:04.760
<v Speaker 1>if you ever have squid ink pasta, that's right. Yeah,

0:14:04.840 --> 0:14:08.760
<v Speaker 1>they're beautiful like charcoal black color in the food. Um,

0:14:08.880 --> 0:14:10.880
<v Speaker 1>I don't know if it really contributes a flavor. I've

0:14:10.920 --> 0:14:13.800
<v Speaker 1>never looked into that. Yeah, And likewise, I don't know

0:14:13.840 --> 0:14:16.040
<v Speaker 1>if putting squid ink in your wine is I'm sure

0:14:16.040 --> 0:14:19.160
<v Speaker 1>it's it would be frowned upon at a rolling restaurant today.

0:14:19.480 --> 0:14:22.600
<v Speaker 1>But saffron, of course, contributes both color and flavor. It's

0:14:22.600 --> 0:14:24.840
<v Speaker 1>got a distinctive kind of aroma. But yeah, you put

0:14:24.840 --> 0:14:27.160
<v Speaker 1>a little bit of saffron and say a pot of rice,

0:14:27.200 --> 0:14:29.720
<v Speaker 1>and it takes on this beautiful golden hue. Yeah. In

0:14:29.720 --> 0:14:33.600
<v Speaker 1>addition to saffron, a few other spices and elements that

0:14:33.640 --> 0:14:37.440
<v Speaker 1>have long been used to color food. Paprika um fabulous,

0:14:37.440 --> 0:14:40.480
<v Speaker 1>tumeric beat extract is a big one, because you know,

0:14:40.480 --> 0:14:44.120
<v Speaker 1>you get that bright red coloration. Long used food dyes.

0:14:44.160 --> 0:14:46.880
<v Speaker 1>All of these, but one that was particularly popular in

0:14:46.920 --> 0:14:50.360
<v Speaker 1>the past Tyrian purple was derived from several species of

0:14:50.360 --> 0:14:53.800
<v Speaker 1>predatory predatory sea snails. Oh yeah, And if you want

0:14:53.800 --> 0:14:57.720
<v Speaker 1>to learn more about the way that the Roman Empire

0:14:57.760 --> 0:15:01.720
<v Speaker 1>and particularly made use of natural occurring substances, check out

0:15:01.720 --> 0:15:04.880
<v Speaker 1>our previous episode on Roman extinctions. Oh yeah, there we

0:15:04.920 --> 0:15:08.640
<v Speaker 1>talk about the cultivation of like silphium and things like that. Now,

0:15:08.680 --> 0:15:11.400
<v Speaker 1>another source that we looked to here was Deborah Bloom's

0:15:11.400 --> 0:15:15.080
<v Speaker 1>book The Poison Squad, and Bloom points out that as

0:15:15.120 --> 0:15:18.360
<v Speaker 1>the Industrial Revolution washed over the world of foods during

0:15:18.960 --> 0:15:22.040
<v Speaker 1>particularly during I think the eighteen Seventies's pointing out here,

0:15:22.560 --> 0:15:26.480
<v Speaker 1>new food processing approaches provided even more new ways and

0:15:26.600 --> 0:15:31.760
<v Speaker 1>new ingredients to commit just lavish food fraud. And this

0:15:31.840 --> 0:15:36.640
<v Speaker 1>included artificial flavors, artificial coloring, and chemical preservatives. And in

0:15:36.640 --> 0:15:39.080
<v Speaker 1>this book she she makes a case for the importance

0:15:39.120 --> 0:15:43.040
<v Speaker 1>of U. S d. A chemist Harvey Washington widely in

0:15:43.240 --> 0:15:46.480
<v Speaker 1>his white Hat efforts to use our advancing knowledge of

0:15:46.560 --> 0:15:49.360
<v Speaker 1>chemical science to stay on top of these many frauds.

0:15:49.920 --> 0:15:52.280
<v Speaker 1>This all in advance of the Meat Inspection Act and

0:15:52.320 --> 0:15:54.800
<v Speaker 1>the Pure Food and Drug Act of nineteen o six,

0:15:55.080 --> 0:15:57.880
<v Speaker 1>which widely helped to bring to fruition. Yeah, he's sort

0:15:57.880 --> 0:16:01.000
<v Speaker 1>of the central character in this book. And it's funny

0:16:01.040 --> 0:16:03.880
<v Speaker 1>that I feel like some of the main chemicals and

0:16:04.000 --> 0:16:08.240
<v Speaker 1>preservatives that he investigated with his famous Poison Squad, which

0:16:08.320 --> 0:16:11.920
<v Speaker 1>was a group of men who would who would essentially

0:16:12.200 --> 0:16:16.400
<v Speaker 1>meet to eat meals together that were contaminated deliberately with

0:16:16.480 --> 0:16:19.680
<v Speaker 1>certain common additives used in food to see how their

0:16:19.720 --> 0:16:24.360
<v Speaker 1>health fared from repeatedly eating things like borax or boric

0:16:24.360 --> 0:16:27.080
<v Speaker 1>acid or whatever, that kind of thing that was used

0:16:27.120 --> 0:16:29.960
<v Speaker 1>to produce stuff. I feel like some of the things

0:16:30.040 --> 0:16:33.640
<v Speaker 1>that the Poison Squad investigated, the jury still kind of

0:16:33.680 --> 0:16:36.760
<v Speaker 1>out on exactly how harmful they were. Maybe they weren't

0:16:36.760 --> 0:16:39.240
<v Speaker 1>as harmful as he thought they were, but clearly at

0:16:39.240 --> 0:16:42.760
<v Speaker 1>this time some food additives were harming and killing people.

0:16:42.800 --> 0:16:46.320
<v Speaker 1>I think especially there was some danger from certain dies. Yes,

0:16:46.960 --> 0:16:49.320
<v Speaker 1>and by the way, the Poison Squad, it sounds like

0:16:49.320 --> 0:16:52.720
<v Speaker 1>it would make a wonderful television series, you know. I mean,

0:16:52.880 --> 0:16:55.760
<v Speaker 1>the public loves a good police procedural, right, This is

0:16:55.800 --> 0:16:57.920
<v Speaker 1>kind of like a little bit police procedural, also a

0:16:57.920 --> 0:17:00.440
<v Speaker 1>little bit you know, the flavoring of say the Nick,

0:17:00.920 --> 0:17:04.760
<v Speaker 1>except with with a food um focus. So I really

0:17:04.800 --> 0:17:08.040
<v Speaker 1>hope it's been optioned one thing audiences love is people

0:17:08.080 --> 0:17:10.760
<v Speaker 1>in the past not knowing things that we know now.

0:17:10.920 --> 0:17:13.480
<v Speaker 1>It's like the scene and Mad Men where the kid

0:17:13.600 --> 0:17:16.920
<v Speaker 1>is playing putting the dry cleaning bag over their head,

0:17:17.080 --> 0:17:19.239
<v Speaker 1>and like the scenes in The Nick where people are

0:17:19.280 --> 0:17:21.240
<v Speaker 1>just like sitting in front of an X ray machine.

0:17:21.600 --> 0:17:23.800
<v Speaker 1>Why does that give us such pleasure to see the

0:17:23.840 --> 0:17:26.760
<v Speaker 1>people of the past punished by their ignorance. I don't

0:17:26.760 --> 0:17:29.080
<v Speaker 1>know one thing I will I think that the Nick

0:17:29.160 --> 0:17:31.600
<v Speaker 1>did a great job with it because they were able

0:17:31.640 --> 0:17:33.800
<v Speaker 1>to They had those moments, for sure, but at the

0:17:33.840 --> 0:17:35.679
<v Speaker 1>same time, they had plenty of moments where they I

0:17:35.680 --> 0:17:40.600
<v Speaker 1>think we're able to effectively convey this sense of modernity

0:17:40.640 --> 0:17:44.080
<v Speaker 1>in in the show that showing you that that even

0:17:44.119 --> 0:17:47.399
<v Speaker 1>if we can look back in hindsight on these various

0:17:47.440 --> 0:17:50.640
<v Speaker 1>techniques in the show in the time frame, they're occurring

0:17:50.680 --> 0:17:53.600
<v Speaker 1>at the just the bleeding edge of our understanding of

0:17:53.600 --> 0:17:57.720
<v Speaker 1>the human body, and it's like retro science fiction. Yeah,

0:17:57.760 --> 0:18:00.359
<v Speaker 1>so obviously, I guess it's you know, it's it's a

0:18:00.400 --> 0:18:03.000
<v Speaker 1>delicate balance to maintain in a show. But like I would,

0:18:03.040 --> 0:18:04.399
<v Speaker 1>I would love to see the same people who did

0:18:04.440 --> 0:18:07.280
<v Speaker 1>the Nick, like do the Poison Squad at least for

0:18:07.280 --> 0:18:11.199
<v Speaker 1>one season, maybe many limited series maybe, but still so.

0:18:11.400 --> 0:18:14.960
<v Speaker 1>The frauds during this time were many. But I think

0:18:14.960 --> 0:18:18.000
<v Speaker 1>one of the more terrifying examples to discuss, just to

0:18:18.080 --> 0:18:21.280
<v Speaker 1>kick things off here is u something that just on

0:18:21.520 --> 0:18:24.720
<v Speaker 1>the face of things will seem like a terrible, if

0:18:24.760 --> 0:18:27.879
<v Speaker 1>not a nefarious idea, and that is lead colored candy.

0:18:29.080 --> 0:18:32.359
<v Speaker 1>So in our past episode on the lead um, I

0:18:32.400 --> 0:18:35.919
<v Speaker 1>believe it was Cupid's leaden arrow. It was a Valentine's

0:18:35.960 --> 0:18:39.080
<v Speaker 1>Day special. We pointed out that even though lead is

0:18:39.160 --> 0:18:42.960
<v Speaker 1>quite poisonous h it tastes. Its taste is also sometimes

0:18:42.960 --> 0:18:47.240
<v Speaker 1>described as sweet, and the ancient Romans used lead salt

0:18:47.280 --> 0:18:49.879
<v Speaker 1>as a sweetener in their syrup. This was known as sapa,

0:18:49.920 --> 0:18:53.600
<v Speaker 1>I believe, and plenty of the Elder once again describes

0:18:53.720 --> 0:18:56.440
<v Speaker 1>the use of lead in vessels with sappa to sweeten

0:18:56.480 --> 0:18:59.120
<v Speaker 1>the taste. Right, Yeah, You've got to boil down your sapa,

0:18:59.200 --> 0:19:01.680
<v Speaker 1>which was like it was a syrup made by reducing

0:19:01.840 --> 0:19:04.919
<v Speaker 1>some kind of wine product I think, um. And so

0:19:05.000 --> 0:19:06.879
<v Speaker 1>you boil it down to make it sweet, and it

0:19:06.920 --> 0:19:09.840
<v Speaker 1>takes on the lead from the pot that it's boiled

0:19:09.840 --> 0:19:11.800
<v Speaker 1>and to become sweeter. He says, don't boil it in

0:19:11.840 --> 0:19:14.040
<v Speaker 1>the copper pot, that's gonna taste bitter. You've got to

0:19:14.080 --> 0:19:16.080
<v Speaker 1>boil it in a lead pot so it tastes nice

0:19:16.080 --> 0:19:19.320
<v Speaker 1>and sweet. So when it comes to candy, obviously, candy

0:19:19.359 --> 0:19:22.639
<v Speaker 1>is generally sweetened through a much more conventional means, namely

0:19:22.760 --> 0:19:26.600
<v Speaker 1>sugar or or some sugar substitute. But during the time

0:19:26.640 --> 0:19:30.800
<v Speaker 1>of Wiley's Wars against Dangerous Foods, children's candy was routinely

0:19:30.920 --> 0:19:34.360
<v Speaker 1>laced with lead and other heavy metals to color it. Yea,

0:19:34.920 --> 0:19:38.560
<v Speaker 1>to impart this kind of you know, the often describes

0:19:38.560 --> 0:19:43.159
<v Speaker 1>a kind of an orange coloration, which is just, you know,

0:19:43.280 --> 0:19:45.560
<v Speaker 1>terrifying to imagine, because I'm just imagining like one of

0:19:45.560 --> 0:19:48.520
<v Speaker 1>these red suckers that you get at the supermarket nowadays,

0:19:48.520 --> 0:19:51.480
<v Speaker 1>and just imagine that being laced with lead and being

0:19:51.520 --> 0:19:54.159
<v Speaker 1>handed to a child right now. It's the CDC points

0:19:54.160 --> 0:19:56.359
<v Speaker 1>out lead was, and in some parts of the world

0:19:56.400 --> 0:19:59.520
<v Speaker 1>still is added to foods not only to impart in

0:19:59.520 --> 0:20:02.639
<v Speaker 1>inviting orange color, but also indeed to sweeten it or

0:20:02.680 --> 0:20:06.040
<v Speaker 1>to increase its weight. Again, getting back to the idea

0:20:06.160 --> 0:20:10.560
<v Speaker 1>that oftentimes food, especially in bulk, is price based on weight.

0:20:10.960 --> 0:20:13.320
<v Speaker 1>That you cut the dope of candy but it's with lead.

0:20:14.800 --> 0:20:17.760
<v Speaker 1>So so that's like three different levels of poisonous deception.

0:20:17.800 --> 0:20:20.880
<v Speaker 1>They're possibly in play in any given piece of lead

0:20:21.000 --> 0:20:23.840
<v Speaker 1>laced candy. Make it cost more via way, make it

0:20:23.840 --> 0:20:27.320
<v Speaker 1>look more attractive via color, and artificially enhanced the flavor

0:20:27.359 --> 0:20:30.159
<v Speaker 1>to some extent as well. Uh and this applies not

0:20:30.280 --> 0:20:33.480
<v Speaker 1>just to candy, but to other food stuffs with lead,

0:20:33.560 --> 0:20:36.840
<v Speaker 1>often introduced via a spice blend. Now, of course, there

0:20:36.840 --> 0:20:39.760
<v Speaker 1>are other ways that lead can get into candy as well.

0:20:40.160 --> 0:20:42.840
<v Speaker 1>Uh and still can get into candy. There's a there

0:20:42.880 --> 0:20:45.239
<v Speaker 1>was case I was looking at in which a six

0:20:45.320 --> 0:20:48.959
<v Speaker 1>year old boy was allegedly poisoned by lead containing uh

0:20:49.320 --> 0:20:53.480
<v Speaker 1>tamarando candy jam products purchased on a visit to Mexico

0:20:53.560 --> 0:20:56.320
<v Speaker 1>with his aunt. However, it seems like a case in

0:20:56.320 --> 0:20:59.159
<v Speaker 1>which the lead contamination was linked to the fact that

0:20:59.280 --> 0:21:02.640
<v Speaker 1>it was quote candy packaged in ceramic jars from Mexico

0:21:02.760 --> 0:21:05.920
<v Speaker 1>at the time, and as the California Department of Health

0:21:05.960 --> 0:21:08.679
<v Speaker 1>points out, it is quote not entirely clear where the

0:21:08.760 --> 0:21:10.840
<v Speaker 1>lead in many of the products is coming from. But

0:21:10.880 --> 0:21:15.120
<v Speaker 1>products containing tamarind, chili powder or salt that is mine

0:21:15.200 --> 0:21:17.560
<v Speaker 1>from certain parts of the world may have a higher

0:21:17.600 --> 0:21:21.119
<v Speaker 1>likelihood of elevated levels of lead. Lead may also be

0:21:21.160 --> 0:21:25.119
<v Speaker 1>introduced into the candy through improper drying, storing, or grinding

0:21:25.200 --> 0:21:28.240
<v Speaker 1>of the ingredients. Now, as we know from our our

0:21:28.280 --> 0:21:31.720
<v Speaker 1>our old alchemist friend Paracelsus, it is of course the

0:21:31.800 --> 0:21:35.119
<v Speaker 1>dose that makes the poison, and this applies in multiple ways.

0:21:35.320 --> 0:21:38.280
<v Speaker 1>It can apply to some things, can be can accumulate

0:21:38.320 --> 0:21:41.159
<v Speaker 1>in the body and their effects over time with chronic exposure.

0:21:41.440 --> 0:21:43.760
<v Speaker 1>Sometimes it also just has to do with an acute dose.

0:21:44.000 --> 0:21:46.800
<v Speaker 1>It's possible that you know, lead compounds have been used

0:21:46.800 --> 0:21:49.359
<v Speaker 1>in many food products over time that if they're in

0:21:49.440 --> 0:21:53.120
<v Speaker 1>small enough concentration, there's not much of a noticeable effect

0:21:53.160 --> 0:21:56.159
<v Speaker 1>on the people who eat them. But I bet in

0:21:56.280 --> 0:21:59.879
<v Speaker 1>many of these cases the concentration of lead in the

0:22:00.000 --> 0:22:03.280
<v Speaker 1>products is probably not very tightly controlled, especially in the

0:22:03.320 --> 0:22:05.520
<v Speaker 1>past and the nineteenth century and stuff. So you might

0:22:05.520 --> 0:22:08.560
<v Speaker 1>get suddenly a gumball or candy that's got a lot

0:22:08.640 --> 0:22:11.879
<v Speaker 1>more lead than usual, leading to you know, high levels

0:22:11.880 --> 0:22:14.840
<v Speaker 1>in an acute sense, but also eating this candy over

0:22:14.920 --> 0:22:17.400
<v Speaker 1>time could lead to effects that people don't even necessarily

0:22:17.400 --> 0:22:20.439
<v Speaker 1>associate with the candy, right. Yeah, And then another factor

0:22:20.480 --> 0:22:22.680
<v Speaker 1>that was brought up in the case study of the

0:22:22.800 --> 0:22:25.159
<v Speaker 1>child is that obviously, like children are going to be

0:22:25.160 --> 0:22:29.720
<v Speaker 1>more susceptible, uh, individuals with smaller body weight, etcetera, which,

0:22:29.720 --> 0:22:32.320
<v Speaker 1>of course is all the more troubling because we are

0:22:32.320 --> 0:22:36.480
<v Speaker 1>talking about candy, which is inherently for children. Alright, time

0:22:36.520 --> 0:22:38.200
<v Speaker 1>to take a break, but we will be right back

0:22:38.240 --> 0:22:43.359
<v Speaker 1>with more. Alright, we're back. Should we talk about some

0:22:43.440 --> 0:22:47.840
<v Speaker 1>more weird color additives? Alright? So these are some more

0:22:47.880 --> 0:22:51.240
<v Speaker 1>examples that come from Adam Borrows j d's palette of

0:22:51.240 --> 0:22:54.960
<v Speaker 1>our palettes. Uh, some of these are a number of

0:22:55.000 --> 0:22:57.000
<v Speaker 1>these are not nefarious, but I'm just going to touch

0:22:57.040 --> 0:22:59.440
<v Speaker 1>on them anyway because it gives I think a broader

0:22:59.520 --> 0:23:01.760
<v Speaker 1>understanding of how and why we color our food and

0:23:01.760 --> 0:23:05.199
<v Speaker 1>what we used to do it. Um coquineal insects have

0:23:05.320 --> 0:23:08.840
<v Speaker 1>long been used to make the dye carmine, traditionally used

0:23:08.840 --> 0:23:12.840
<v Speaker 1>in fabrics. It also pops up in cosmetics and food coloring. Again,

0:23:12.920 --> 0:23:15.440
<v Speaker 1>not deadly unless you're one of the insects that gets

0:23:15.440 --> 0:23:18.119
<v Speaker 1>ground up to in part of a reddish coloration, but

0:23:18.200 --> 0:23:22.560
<v Speaker 1>it's still interesting. Saffron we already touched on, also not deadly, though,

0:23:22.560 --> 0:23:24.919
<v Speaker 1>of course, with any spice. You'll run into adverse reactions

0:23:24.920 --> 0:23:27.600
<v Speaker 1>if you consume too much of it. A little saffron

0:23:27.680 --> 0:23:30.280
<v Speaker 1>tends to go along long way. It's derived from the

0:23:30.359 --> 0:23:33.720
<v Speaker 1>saffron crocus flour, and it's long been used in cooking,

0:23:33.720 --> 0:23:36.399
<v Speaker 1>both for its flavor and for its strong yellow coloration.

0:23:36.800 --> 0:23:40.240
<v Speaker 1>Now we mentioned earlier like cutting the dope, adding something

0:23:40.280 --> 0:23:42.720
<v Speaker 1>that's not the dope to the dope that you know,

0:23:42.760 --> 0:23:46.520
<v Speaker 1>bulkes it up and makes it more attractive initially. And

0:23:46.640 --> 0:23:50.280
<v Speaker 1>this leads us to a famous quote from a giant,

0:23:50.720 --> 0:23:53.680
<v Speaker 1>I'll grind your bones to make my bread. Oh yeah,

0:23:53.760 --> 0:23:56.239
<v Speaker 1>that's from Jack and the Beans saw. Yeah. Yeah. So

0:23:56.280 --> 0:23:59.000
<v Speaker 1>he climbs up there and and the giant, I don't

0:23:59.040 --> 0:24:01.600
<v Speaker 1>get it. Why is he grin ending his bones? Yeah.

0:24:01.640 --> 0:24:03.359
<v Speaker 1>I always troubled me as a kid because I'm like,

0:24:03.400 --> 0:24:05.919
<v Speaker 1>I don't know not much about bread making. I'm not

0:24:06.000 --> 0:24:08.760
<v Speaker 1>a baker, but I know you don't make bread out

0:24:08.800 --> 0:24:11.320
<v Speaker 1>of bones that are ground up. It makes a little

0:24:11.400 --> 0:24:15.160
<v Speaker 1>more sense, though, when you understand that a typical medieval

0:24:15.240 --> 0:24:20.280
<v Speaker 1>baker's trick was to brighten up bread by using ground bone,

0:24:20.560 --> 0:24:24.960
<v Speaker 1>lime or chalk. Whoa. In fact, Keen Edward the first

0:24:25.040 --> 0:24:28.560
<v Speaker 1>outlied this practice and uh, and here's a here's a

0:24:28.600 --> 0:24:32.479
<v Speaker 1>reading of the law. If any default shall be found

0:24:32.560 --> 0:24:35.080
<v Speaker 1>in the bread of a baker in the city the

0:24:35.160 --> 0:24:38.080
<v Speaker 1>first time, let him be drawn upon a hurdle from

0:24:38.080 --> 0:24:40.879
<v Speaker 1>the guild hall to his own house, through the great street,

0:24:41.280 --> 0:24:44.200
<v Speaker 1>where there be most people assembled, and through the streets

0:24:44.200 --> 0:24:47.280
<v Speaker 1>which are most dirty, with the faulty loaf hanging from

0:24:47.359 --> 0:24:50.040
<v Speaker 1>his neck. If a second time he shall be found

0:24:50.040 --> 0:24:53.000
<v Speaker 1>committing the same offense, let him be drawn from the

0:24:53.040 --> 0:24:56.240
<v Speaker 1>guild hall, through the great Street of cheap Ee to

0:24:56.359 --> 0:24:58.920
<v Speaker 1>the pillory, And let him be put upon the pillory,

0:24:59.000 --> 0:25:02.320
<v Speaker 1>and remain there least one hour in the day. And

0:25:02.359 --> 0:25:05.520
<v Speaker 1>the third time that such default shall be found, be

0:25:05.720 --> 0:25:09.560
<v Speaker 1>shall be drawn, and the oven shall be pulled down,

0:25:09.680 --> 0:25:12.080
<v Speaker 1>and the baker made to forswear the trade in the

0:25:12.160 --> 0:25:16.520
<v Speaker 1>city forever. Whoa the shame walk with bread around your neck.

0:25:17.080 --> 0:25:19.520
<v Speaker 1>That's what you get if you put bone or something

0:25:19.560 --> 0:25:23.919
<v Speaker 1>else in the bread. Victorian era Europe saw copper salts

0:25:24.080 --> 0:25:27.720
<v Speaker 1>used to turn pickles and vegetables of a brighter green color. Apparently,

0:25:28.240 --> 0:25:33.040
<v Speaker 1>and as described in eighteen twenty by English chemist Frederick Acum,

0:25:33.600 --> 0:25:36.719
<v Speaker 1>a key individual in the crackdown on illicit additives at

0:25:36.760 --> 0:25:39.840
<v Speaker 1>the time. Uh. He said the following this quote comes

0:25:39.840 --> 0:25:43.679
<v Speaker 1>from Burrows Uh right up as well. Quote. Vegetable substances

0:25:43.760 --> 0:25:47.760
<v Speaker 1>preserved in a state called pickles wholesale frequently depends greatly

0:25:47.840 --> 0:25:51.960
<v Speaker 1>upon a fine, lively green color, and sometimes intentionally colored

0:25:52.000 --> 0:25:55.000
<v Speaker 1>by means of copper. A young lady amused herself by

0:25:55.000 --> 0:25:58.720
<v Speaker 1>eating pickles impregnated with copper. She soon complained of a

0:25:58.760 --> 0:26:02.119
<v Speaker 1>pain in her stomach in nine days after eating the pickle.

0:26:02.440 --> 0:26:06.320
<v Speaker 1>Death relieved her of her suffering. Whoa and Acam also

0:26:06.400 --> 0:26:09.440
<v Speaker 1>pointed to the use of these coloring additives in candies

0:26:09.880 --> 0:26:13.200
<v Speaker 1>uh and in which he pointed out vermilion would contain

0:26:13.359 --> 0:26:17.800
<v Speaker 1>mercury red lead, it was another one white lead, verdigris,

0:26:17.960 --> 0:26:21.800
<v Speaker 1>which is a copper salt blue vitriol which contains copper,

0:26:22.040 --> 0:26:26.160
<v Speaker 1>and then sheilds green, which contains copper and arsenic shields.

0:26:26.160 --> 0:26:30.679
<v Speaker 1>Green is a massive historical case of I think primarily

0:26:30.760 --> 0:26:34.080
<v Speaker 1>not used in food, right, primarily used in like I

0:26:34.080 --> 0:26:37.520
<v Speaker 1>don't know, coloring walls and stuff like that, but I

0:26:37.600 --> 0:26:39.280
<v Speaker 1>think you see that with a few of these different things,

0:26:39.280 --> 0:26:41.119
<v Speaker 1>like there'll be a die and it's fine if you're

0:26:41.200 --> 0:26:43.639
<v Speaker 1>dyeing fabrics, with it, but then to turn around and

0:26:43.800 --> 0:26:46.359
<v Speaker 1>use it in food is either you know, it is

0:26:46.400 --> 0:26:49.679
<v Speaker 1>at least ill advised, if not in like a nefarious act. Oh,

0:26:49.720 --> 0:26:51.919
<v Speaker 1>I'm not saying siels green is fine. I think sheilds

0:26:51.960 --> 0:26:55.000
<v Speaker 1>green is famous for poisoning people in history, like even

0:26:55.000 --> 0:26:57.240
<v Speaker 1>through fabric it was one of the real bad ones.

0:26:58.080 --> 0:27:01.720
<v Speaker 1>In addition, iron compounds were sometimes used to redden up foods,

0:27:02.080 --> 0:27:05.280
<v Speaker 1>and then the dye Prussian blue along with yellow gypsum,

0:27:05.320 --> 0:27:07.920
<v Speaker 1>we're often added to Chinese green teas to make them

0:27:08.080 --> 0:27:11.760
<v Speaker 1>more green and inviting to foreign markets. Uh and put

0:27:11.760 --> 0:27:14.359
<v Speaker 1>in Prussian blue contained arsenic. This reminds me of the

0:27:15.240 --> 0:27:18.920
<v Speaker 1>uh the situation with absinthe um when you when you

0:27:18.960 --> 0:27:22.000
<v Speaker 1>see like a selection of absence at a you know

0:27:22.040 --> 0:27:26.240
<v Speaker 1>absinthe bar. Generally speaking, if I remember correctly, you're gonna

0:27:26.280 --> 0:27:27.840
<v Speaker 1>want to go for the ones that do not look

0:27:27.880 --> 0:27:31.160
<v Speaker 1>as much like storybook absinthe like. The more it looks

0:27:31.200 --> 0:27:33.879
<v Speaker 1>like mouthwash like it's a sign that some sort of

0:27:34.280 --> 0:27:37.400
<v Speaker 1>coloration has been added, probably not arsenic. I'm not saying

0:27:37.440 --> 0:27:41.080
<v Speaker 1>it's arsenic, but but something has been added to enhance

0:27:41.320 --> 0:27:44.520
<v Speaker 1>that coloration and make it more attractive to at least

0:27:44.560 --> 0:27:47.960
<v Speaker 1>the casual audience, I see it make it uh to

0:27:48.080 --> 0:27:52.040
<v Speaker 1>use a tokenism, look fairer and taste fouler yes. And

0:27:52.080 --> 0:27:54.720
<v Speaker 1>then there's the coloring of butter and butter like products.

0:27:55.000 --> 0:27:58.200
<v Speaker 1>Burrows points out that there was a thirteen French edict

0:27:58.240 --> 0:28:01.440
<v Speaker 1>against coloring butter, and late a fifteen seventy four law

0:28:01.560 --> 0:28:04.800
<v Speaker 1>preventing the use of colors and pastries to simulate the

0:28:04.840 --> 0:28:07.360
<v Speaker 1>presence of eggs. And then there were the then there're

0:28:07.400 --> 0:28:09.640
<v Speaker 1>the margarine Wars, which we've touched on on the show

0:28:09.640 --> 0:28:13.040
<v Speaker 1>in the past, in which butter manufacturers sought to protect

0:28:13.119 --> 0:28:16.560
<v Speaker 1>their turf by seeking laws against yellow dyes and margarine,

0:28:17.160 --> 0:28:20.600
<v Speaker 1>and and even though adding the requirement of pink dye

0:28:20.880 --> 0:28:23.879
<v Speaker 1>to make it clear that margarine was not butter, and

0:28:23.880 --> 0:28:26.159
<v Speaker 1>in fact the U. S. Supreme Court had to intervene

0:28:26.200 --> 0:28:29.520
<v Speaker 1>and overturned state laws in thirty two pro butter states

0:28:30.080 --> 0:28:33.919
<v Speaker 1>according to the Butter Wars by publishing nat Geo. And

0:28:34.000 --> 0:28:36.879
<v Speaker 1>this was by Rebecca Rupp. Now, again, while it is

0:28:36.880 --> 0:28:41.200
<v Speaker 1>clear that some compounds used as dies in history have

0:28:41.400 --> 0:28:43.920
<v Speaker 1>turned out to be dangerous in one form or another,

0:28:44.000 --> 0:28:46.600
<v Speaker 1>this is certainly not to suggest that all or even

0:28:46.680 --> 0:28:49.800
<v Speaker 1>most of these compounds have any kind of negative health effects,

0:28:49.840 --> 0:28:53.440
<v Speaker 1>but concerns about such have definitely continued into the modern

0:28:53.480 --> 0:28:57.080
<v Speaker 1>area era, whether founded or not. Yeah, And if you

0:28:57.080 --> 0:28:59.400
<v Speaker 1>want to learn more about this sort of the modern

0:28:59.520 --> 0:29:05.440
<v Speaker 1>state and recent history of of of die considerations, die outraged, die, pendics, etcetera,

0:29:05.840 --> 0:29:08.480
<v Speaker 1>I'd refer you to Burrows for more on this because

0:29:08.480 --> 0:29:10.479
<v Speaker 1>he gets into a lot of the concerns over modern

0:29:10.560 --> 0:29:14.000
<v Speaker 1>dies and sometimes the urban legends about their dangers, such

0:29:14.040 --> 0:29:17.160
<v Speaker 1>as the notion that Mountain Dew's yellow in our five

0:29:17.280 --> 0:29:20.600
<v Speaker 1>reduces sperm count, which which is not the case, but

0:29:20.720 --> 0:29:22.400
<v Speaker 1>that was like that was an urban legend that was

0:29:22.440 --> 0:29:25.760
<v Speaker 1>making the rounds at one point. However, I will leave

0:29:26.280 --> 0:29:28.440
<v Speaker 1>leave you all with this quote from Burrows on the

0:29:28.520 --> 0:29:31.120
<v Speaker 1>history and future of color additives. I think he sums

0:29:31.160 --> 0:29:33.920
<v Speaker 1>us up nicely. Quote. It is hard to believe that

0:29:34.000 --> 0:29:37.680
<v Speaker 1>only a century ago our ancestors were eating food died

0:29:37.680 --> 0:29:41.760
<v Speaker 1>with highly toxic color additives. From that auspicious starting point,

0:29:42.000 --> 0:29:44.120
<v Speaker 1>we have come to a time where a food colorant

0:29:44.400 --> 0:29:47.720
<v Speaker 1>with a one in nineteen billion chance of causing cancer

0:29:47.920 --> 0:29:51.120
<v Speaker 1>is legally considered too dangerous. What we used to die

0:29:51.120 --> 0:29:54.200
<v Speaker 1>our foods and how we regulated may continue to change,

0:29:54.280 --> 0:29:56.400
<v Speaker 1>but there is no end in sight to the timeless

0:29:56.400 --> 0:30:00.680
<v Speaker 1>practice of coloring our food. This is interest ing, like

0:30:01.080 --> 0:30:03.400
<v Speaker 1>the idea that I don't know, whenever you're making a

0:30:03.480 --> 0:30:06.360
<v Speaker 1>ruling on this kind of thing, you can't you can't

0:30:06.360 --> 0:30:10.320
<v Speaker 1>ever say that something is you're sure one hundred percent safe?

0:30:10.680 --> 0:30:13.960
<v Speaker 1>So like, what's the threshold you're comfortable with You're like, Okay,

0:30:14.240 --> 0:30:17.560
<v Speaker 1>maybe if we use this die in fruit loops for

0:30:17.640 --> 0:30:22.560
<v Speaker 1>a hundred years, one person will be killed by it.

0:30:21.920 --> 0:30:25.800
<v Speaker 1>Is that like, do we just decide, Okay, if it's

0:30:25.880 --> 0:30:28.960
<v Speaker 1>just one person every hundred years getting killed by the die,

0:30:29.080 --> 0:30:33.000
<v Speaker 1>then it's okay. Yeah. And I wondered to, like to what, like,

0:30:33.040 --> 0:30:36.400
<v Speaker 1>what is our ultimate relationship with the idea of adding

0:30:36.440 --> 0:30:40.040
<v Speaker 1>die to a food product? Is it one of I mean,

0:30:40.080 --> 0:30:42.320
<v Speaker 1>if we're oblivious to it, is just oh, it's this

0:30:42.360 --> 0:30:44.720
<v Speaker 1>is super red. I'm very attracted to it. I must

0:30:44.720 --> 0:30:47.600
<v Speaker 1>have this candy or apple or whatever the product is. Well,

0:30:47.640 --> 0:30:50.200
<v Speaker 1>we with the eyes first, but but then if if

0:30:50.560 --> 0:30:53.600
<v Speaker 1>there also seems to be this this this this broad

0:30:53.680 --> 0:30:58.520
<v Speaker 1>category of just distrust associated with food coloration as well, Uh,

0:30:58.560 --> 0:31:01.480
<v Speaker 1>this this idea that and still you know pretty early

0:31:01.520 --> 0:31:04.800
<v Speaker 1>on via some of these frauds that were perpetrated the

0:31:04.840 --> 0:31:07.120
<v Speaker 1>idea that if there's some sort of artificial color there,

0:31:07.160 --> 0:31:09.880
<v Speaker 1>there's something in the food that should not be there. Uh,

0:31:09.960 --> 0:31:13.600
<v Speaker 1>they're like the understanding that this food is super red

0:31:13.720 --> 0:31:17.160
<v Speaker 1>in an unnatural way. Um, why is that the case?

0:31:17.280 --> 0:31:19.800
<v Speaker 1>Something is trying to fool me with this food. It's

0:31:19.840 --> 0:31:23.000
<v Speaker 1>the post Watergate era of relationship with foods. I mean,

0:31:23.440 --> 0:31:27.520
<v Speaker 1>you know, it's are just general uh distrustful attitude in

0:31:27.560 --> 0:31:30.280
<v Speaker 1>the modern world. I think you know, there there are

0:31:30.360 --> 0:31:32.760
<v Speaker 1>reasons for us to feel that way, even if we're

0:31:32.760 --> 0:31:37.520
<v Speaker 1>not necessarily correct about perceived dangers and industrial additives to

0:31:37.680 --> 0:31:40.800
<v Speaker 1>food products. And another thing I wanted to clarify. I

0:31:40.800 --> 0:31:43.800
<v Speaker 1>know that when you say that, you know, when you're

0:31:43.800 --> 0:31:46.320
<v Speaker 1>talking about a one in nineteen billion chance of a

0:31:46.400 --> 0:31:50.840
<v Speaker 1>die killing somebody, I understand that's talking about like confidence intervals.

0:31:50.880 --> 0:31:53.720
<v Speaker 1>That doesn't literally mean that like one person will die

0:31:53.840 --> 0:31:55.719
<v Speaker 1>for every you know, it is just a way of

0:31:55.720 --> 0:31:59.400
<v Speaker 1>expressing how confident you are generally that something is safe.

0:31:59.440 --> 0:32:02.000
<v Speaker 1>And again I recommend everyone to check out that Borrows

0:32:02.080 --> 0:32:05.160
<v Speaker 1>article if you want more, you know, in depth consideration

0:32:05.240 --> 0:32:08.920
<v Speaker 1>of dies. But I think that's that's probably enough for

0:32:08.920 --> 0:32:12.120
<v Speaker 1>for food additives for dies. At this point, we're gonna

0:32:12.120 --> 0:32:14.480
<v Speaker 1>take a quick break and when we come back, we're

0:32:14.560 --> 0:32:20.960
<v Speaker 1>going to open up some beer. Alright, we're back now.

0:32:21.040 --> 0:32:23.280
<v Speaker 1>I want to start with we we've done these in

0:32:23.360 --> 0:32:27.560
<v Speaker 1>some of the dangerous food episodes in the past, to

0:32:27.560 --> 0:32:31.440
<v Speaker 1>to do a little sort of epidemiological detective story where

0:32:31.440 --> 0:32:33.840
<v Speaker 1>there's a sudden outbreak of symptoms and then people are

0:32:33.840 --> 0:32:36.560
<v Speaker 1>trying to figure out what caused it. Uh So, we're

0:32:36.600 --> 0:32:39.200
<v Speaker 1>gonna go back to the nineteen sixties to the mid

0:32:39.240 --> 0:32:43.600
<v Speaker 1>to late nineteen sixties, and in this period, doctors in

0:32:43.720 --> 0:32:47.720
<v Speaker 1>hospitals and clinics across a number of metro areas in Europe,

0:32:47.760 --> 0:32:51.360
<v Speaker 1>in the United States, and Canada begin to notice a

0:32:51.520 --> 0:32:56.240
<v Speaker 1>strange pattern of cases, patients showing up with a sudden

0:32:56.360 --> 0:33:01.040
<v Speaker 1>onset of an unusual form of cardiomya pathy, which is

0:33:01.080 --> 0:33:03.880
<v Speaker 1>a disease of the heart muscle in which parts of

0:33:03.920 --> 0:33:07.720
<v Speaker 1>the heart can become enlarged or stiff for just generally

0:33:07.840 --> 0:33:12.720
<v Speaker 1>aren't working properly. Uh So, between August nineteen sixty five

0:33:12.880 --> 0:33:17.160
<v Speaker 1>and April nineteen sixty six, a rash of cases appeared

0:33:17.200 --> 0:33:20.440
<v Speaker 1>around the area of Quebec City in Canada, enough to

0:33:20.600 --> 0:33:22.840
<v Speaker 1>signal that there was some kind of pattern going on

0:33:22.960 --> 0:33:27.040
<v Speaker 1>to local clinicians and pathologists who at first thought, well,

0:33:27.040 --> 0:33:30.280
<v Speaker 1>maybe the epidemic is viral in nature, But a study

0:33:30.280 --> 0:33:33.440
<v Speaker 1>of thirty patients could not isolate a viral cause for

0:33:33.480 --> 0:33:36.920
<v Speaker 1>this strange kind of cardiomyopathy. Uh and this was described

0:33:36.920 --> 0:33:40.440
<v Speaker 1>in the nineteen sixty seven report I'll sight in a minute. Instead,

0:33:40.520 --> 0:33:43.280
<v Speaker 1>what the patients seem to have in common was that

0:33:43.360 --> 0:33:48.640
<v Speaker 1>they were all heavy beer drinkers. Um. So, alcoholic beverages

0:33:48.680 --> 0:33:51.160
<v Speaker 1>are an interesting case to explore when you're talking about

0:33:51.240 --> 0:33:55.240
<v Speaker 1>you know, dangerous foods, because alcoholic beverages already contain a

0:33:55.360 --> 0:34:00.680
<v Speaker 1>perfectly powerful and dangerous active ingredient, which is alcohol. According

0:34:00.680 --> 0:34:02.560
<v Speaker 1>to itally by the U s c d C. And

0:34:03.800 --> 0:34:07.960
<v Speaker 1>about people in the United States die every year from

0:34:08.000 --> 0:34:11.839
<v Speaker 1>alcohol poisoning. And that's just alcohol poisoning, which is an

0:34:11.840 --> 0:34:15.600
<v Speaker 1>acute overdose of alcohol leading directly to death. If you

0:34:15.680 --> 0:34:19.040
<v Speaker 1>expand that number to alcohol related deaths such as you know,

0:34:19.120 --> 0:34:22.440
<v Speaker 1>deaths from from chronic alcohol abuse, or include stuff like

0:34:22.440 --> 0:34:25.360
<v Speaker 1>you know, traffic collisions caused by people driving under the influence,

0:34:25.400 --> 0:34:27.680
<v Speaker 1>the number is obviously going to be a lot higher. Yeah,

0:34:28.600 --> 0:34:31.360
<v Speaker 1>among other things, it is a great insight into the

0:34:31.360 --> 0:34:34.880
<v Speaker 1>the uneven way in which we uh we we we

0:34:34.880 --> 0:34:39.960
<v Speaker 1>we we govern the consumption and purchase of various dangerous substances.

0:34:39.960 --> 0:34:44.080
<v Speaker 1>Oh absolutely, but for yeah, so for alcohol poisoning alone

0:34:45.160 --> 0:34:48.280
<v Speaker 1>people every year as of that's an average of six

0:34:48.360 --> 0:34:50.920
<v Speaker 1>people who die every single day, and just in the

0:34:51.000 --> 0:34:54.359
<v Speaker 1>United States, and an overwhelming majority of the people who

0:34:54.400 --> 0:34:58.240
<v Speaker 1>die from alcohol poisoning are adult men. Seventy six percent

0:34:58.400 --> 0:35:02.160
<v Speaker 1>of deaths from our called poisoning occur among men, and

0:35:02.280 --> 0:35:05.760
<v Speaker 1>seventy six are also between people of the ages thirty

0:35:05.760 --> 0:35:08.439
<v Speaker 1>five to sixty four. And of course the primary cause

0:35:08.480 --> 0:35:11.240
<v Speaker 1>of death in these cases is suppression of the life

0:35:11.239 --> 0:35:14.880
<v Speaker 1>sustaining functions of the brain and the central nervous system. Alright,

0:35:14.920 --> 0:35:18.880
<v Speaker 1>so the basic scenario is you have a population of

0:35:18.880 --> 0:35:21.760
<v Speaker 1>people who are already drinking something that is arguably poison

0:35:22.360 --> 0:35:26.279
<v Speaker 1>but something else may be involved. Right, These cases of

0:35:26.320 --> 0:35:29.720
<v Speaker 1>cardio myopathy did not seem to stem from the acute

0:35:29.840 --> 0:35:33.840
<v Speaker 1>or chronic effects of alcohol itself. So look at a study,

0:35:33.920 --> 0:35:36.439
<v Speaker 1>the sort of breakthrough study on on the first big

0:35:36.480 --> 0:35:39.840
<v Speaker 1>look at this It was by Eve's Marine and Philippe

0:35:39.920 --> 0:35:45.960
<v Speaker 1>Daniel called Quebec Beer drinkers cardio myopathy ideological considerations that means,

0:35:46.000 --> 0:35:49.760
<v Speaker 1>considerations for the origin of this outbreak. It was published

0:35:49.760 --> 0:35:53.200
<v Speaker 1>in the Canadian Medical Association Journal in nineteen sixty seven,

0:35:53.800 --> 0:35:56.680
<v Speaker 1>and the authors here mentioned that there was a similar

0:35:56.680 --> 0:36:00.200
<v Speaker 1>outbreak of sudden cardio myopathy in Omaha. No brass Ka

0:36:00.800 --> 0:36:02.960
<v Speaker 1>I was also looking at the nineteen seventy two paper

0:36:03.000 --> 0:36:06.720
<v Speaker 1>by a doctor named Carl S. Alexander describing an outbreak

0:36:06.760 --> 0:36:09.520
<v Speaker 1>of cardio myopathy and twenty eight patients admitted to the

0:36:09.600 --> 0:36:13.960
<v Speaker 1>VA Hospital in Minneapolis, Minnesota, between nineteen sixty four and

0:36:14.040 --> 0:36:17.239
<v Speaker 1>nineteen sixty seven, So again mid mid to late sixties,

0:36:18.200 --> 0:36:22.200
<v Speaker 1>especially in these Midwestern and northern cities, sudden outbreak of

0:36:22.200 --> 0:36:26.040
<v Speaker 1>of strange type of heart disease UH. And again what

0:36:26.239 --> 0:36:28.680
<v Speaker 1>these cases seem to have in common was heavy consumption

0:36:28.719 --> 0:36:33.600
<v Speaker 1>of beer and sudden unusual cardio myopathy. So, according to Alexander,

0:36:33.760 --> 0:36:37.239
<v Speaker 1>a total of forty two patients with acute cardiac distress

0:36:37.520 --> 0:36:40.840
<v Speaker 1>were admitted to the hospital in Minneapolis, but the study

0:36:40.880 --> 0:36:43.320
<v Speaker 1>focused on just twenty eight of them because those twenty

0:36:43.320 --> 0:36:46.319
<v Speaker 1>eight admitted to drinking up to thirty bottles of not

0:36:46.440 --> 0:36:51.920
<v Speaker 1>just beer, but one particular brand of beer Brand X

0:36:52.000 --> 0:36:56.480
<v Speaker 1>in Alexander's paper and denied drinking any other alcoholic beverages.

0:36:56.560 --> 0:36:59.480
<v Speaker 1>The other fourteen patients were excluded from the initial study

0:36:59.520 --> 0:37:02.600
<v Speaker 1>because they drank other kinds of alcohol as well as

0:37:02.640 --> 0:37:05.600
<v Speaker 1>Brand X beer. Actually, now brand X is just to

0:37:05.840 --> 0:37:09.320
<v Speaker 1>cover the name of the actual manufacturer, right right, And

0:37:09.480 --> 0:37:12.040
<v Speaker 1>that's just in the literature. I will name one of

0:37:12.120 --> 0:37:15.600
<v Speaker 1>the culprits that we get too log on. But yeah,

0:37:15.719 --> 0:37:18.640
<v Speaker 1>Alexander's paper was published in seventy two in the American

0:37:18.680 --> 0:37:21.200
<v Speaker 1>Journal of Medicine. And again this is looking at a

0:37:21.239 --> 0:37:25.600
<v Speaker 1>broader study of of this phenomenon. Here now, Alexander mentions

0:37:25.640 --> 0:37:29.800
<v Speaker 1>that there are types of cardiomyopathy that you would otherwise

0:37:29.840 --> 0:37:33.320
<v Speaker 1>expect to find among patients with alcoholism, and these cases

0:37:33.840 --> 0:37:37.840
<v Speaker 1>were different in their symptoms and onset. Like Alexander says, quote,

0:37:37.880 --> 0:37:42.120
<v Speaker 1>the syndrome differed from alcoholic cardiomyopathy and berry berry which

0:37:42.120 --> 0:37:45.719
<v Speaker 1>again that's another related disease caused by a deficiency of

0:37:45.800 --> 0:37:50.319
<v Speaker 1>vitamin B one also known as thiamine. And Alexander says

0:37:50.360 --> 0:37:52.840
<v Speaker 1>the way it differed from these other known conditions was

0:37:52.920 --> 0:37:56.760
<v Speaker 1>quote in its rather abrupt onset of left ventricular failure,

0:37:57.040 --> 0:38:01.560
<v Speaker 1>cardiogenic shock and acids. So cardiogenic shock is when the

0:38:01.560 --> 0:38:04.840
<v Speaker 1>heart suddenly fails to pump enough blood to provide circulation

0:38:04.880 --> 0:38:06.840
<v Speaker 1>to the rest of the body, often happens as the

0:38:06.840 --> 0:38:10.120
<v Speaker 1>result of a heart attack. Acidosis is an imbalance in

0:38:10.120 --> 0:38:12.440
<v Speaker 1>the pH of the blood in which the blood plasma

0:38:12.520 --> 0:38:17.279
<v Speaker 1>becomes overly acidic. Alexander also mentions two other unique features

0:38:17.320 --> 0:38:21.239
<v Speaker 1>of these apparent epidemics, as identified in Belgium by a

0:38:21.280 --> 0:38:25.879
<v Speaker 1>doctor named Kes Salute uh and these were pericardial effusion.

0:38:26.040 --> 0:38:29.359
<v Speaker 1>And this is when there's an excess of fluids surrounding

0:38:29.400 --> 0:38:32.719
<v Speaker 1>the heart inside the pericardium, which is a kind of

0:38:32.800 --> 0:38:35.160
<v Speaker 1>sack that surrounds the heart muscle. So you've got the

0:38:35.160 --> 0:38:38.040
<v Speaker 1>heart is inside its sack, and then there's a bunch

0:38:38.040 --> 0:38:41.520
<v Speaker 1>of fluid in that sack, and then there is UH.

0:38:41.560 --> 0:38:45.280
<v Speaker 1>There were also elevated hemoglobin levels. Hemoglobin is the protein

0:38:45.360 --> 0:38:48.400
<v Speaker 1>in red blood cells that the body uses to transport

0:38:48.440 --> 0:38:51.919
<v Speaker 1>oxygen molecules from the lungs to the rest of the body. Uh.

0:38:51.920 --> 0:38:54.799
<v Speaker 1>And you might see elevated levels of hemoglobin in any

0:38:54.880 --> 0:38:58.760
<v Speaker 1>kind of condition where the body is struggling to supply

0:38:58.840 --> 0:39:03.120
<v Speaker 1>itself with enough oxygen. So This could range from high altitude,

0:39:03.160 --> 0:39:05.440
<v Speaker 1>say right, because you know you're not getting enough with

0:39:05.480 --> 0:39:08.040
<v Speaker 1>each breath, so you see increased hemoglobin in the blood,

0:39:08.239 --> 0:39:11.919
<v Speaker 1>to various lung and heart diseases. Alexander mentions that among

0:39:11.960 --> 0:39:16.560
<v Speaker 1>the patients he reviewed, acute mortality was eighteen percent, but

0:39:16.640 --> 0:39:20.040
<v Speaker 1>the disease was associated with lingering symptoms and disabilities that

0:39:20.080 --> 0:39:23.239
<v Speaker 1>led to a total mortality of forty three percent. So

0:39:23.640 --> 0:39:26.000
<v Speaker 1>ultimately forty three percent of the people he saw with

0:39:26.040 --> 0:39:28.640
<v Speaker 1>this condition died from it, and so it took a

0:39:28.680 --> 0:39:31.480
<v Speaker 1>bit of work to isolate the cause of these outbreaks,

0:39:31.560 --> 0:39:34.440
<v Speaker 1>especially it was in the first one in Quebec City

0:39:34.520 --> 0:39:37.440
<v Speaker 1>in the years nineteen sixty five to nineteen sixty six.

0:39:37.920 --> 0:39:41.680
<v Speaker 1>The investigating physicians established that it probably was not caused

0:39:41.680 --> 0:39:44.120
<v Speaker 1>by a virus, that it seemed to be associated with

0:39:44.160 --> 0:39:47.080
<v Speaker 1>heavy beer drinking, but that it didn't look like normal

0:39:47.120 --> 0:39:51.319
<v Speaker 1>alcoholic cardiomyopathy, and they discovered something else similar to what

0:39:51.560 --> 0:39:55.000
<v Speaker 1>Alexander discovered later in his study about the Minneapolis patients.

0:39:55.400 --> 0:39:57.839
<v Speaker 1>In Quebec City, it wasn't just that the patients were

0:39:57.840 --> 0:40:01.359
<v Speaker 1>heavy beer drinkers. They drank a lot of one specific

0:40:01.560 --> 0:40:05.160
<v Speaker 1>brand of beer, uh Morn, and Daniel speaking of this

0:40:05.239 --> 0:40:08.759
<v Speaker 1>brewery that made this beer quote, it's excellent tasting. Brew

0:40:09.000 --> 0:40:11.920
<v Speaker 1>was and still is very popular in Quebec and accounts

0:40:11.920 --> 0:40:16.120
<v Speaker 1>for approximately eight of the local market. Later reports revealed

0:40:16.120 --> 0:40:19.960
<v Speaker 1>this to be the Tao Brewery. So quick question, does

0:40:20.000 --> 0:40:22.840
<v Speaker 1>this have does this have any uh? Did this inspire

0:40:22.920 --> 0:40:26.720
<v Speaker 1>the movie Strange Brew? Is there anything I haven't seen Strange?

0:40:26.960 --> 0:40:29.200
<v Speaker 1>I've never seen it either. I just okay, well, I'm

0:40:29.239 --> 0:40:31.759
<v Speaker 1>just familiar with it by you know, reputation that it

0:40:32.160 --> 0:40:35.440
<v Speaker 1>concerns some sort of strange Canadian brew of beer and

0:40:35.480 --> 0:40:38.239
<v Speaker 1>it's you know, cinematic powers. I kind of doubt it

0:40:38.239 --> 0:40:40.319
<v Speaker 1>because I think that movie is a comedy and this

0:40:40.480 --> 0:40:43.319
<v Speaker 1>ultimately is not that funny of a story, though it

0:40:43.360 --> 0:40:45.200
<v Speaker 1>does have I don't know, I guess it has some

0:40:45.280 --> 0:40:49.840
<v Speaker 1>funny tragedy plus time comedy. Right. Yes, of course what

0:40:49.880 --> 0:40:51.680
<v Speaker 1>happened to the people who drank it is not funny,

0:40:51.760 --> 0:40:54.080
<v Speaker 1>But like when you when we find out what was

0:40:54.160 --> 0:40:57.919
<v Speaker 1>causing this, it is actually kind of strange. So Morin

0:40:58.040 --> 0:41:01.080
<v Speaker 1>and Daniel mentioned that they were inspired to look more

0:41:01.120 --> 0:41:04.120
<v Speaker 1>closely at the constituents of the beer made by this

0:41:04.200 --> 0:41:08.640
<v Speaker 1>brewery because of a specific historical analogy and that's the

0:41:08.760 --> 0:41:12.759
<v Speaker 1>Great English beer poisoning of nineteen hundred. Uh. This was

0:41:12.800 --> 0:41:16.000
<v Speaker 1>an incident in which thousands of people across Middle and

0:41:16.080 --> 0:41:20.080
<v Speaker 1>Northwest England, especially in the city of Manchester, were poisoned

0:41:20.120 --> 0:41:23.520
<v Speaker 1>by beer. Of the thousands who were poisoned, at least

0:41:23.560 --> 0:41:25.880
<v Speaker 1>around seventy or so died. And I think it was

0:41:25.920 --> 0:41:28.160
<v Speaker 1>originally believed to be nothing more than a bunch of

0:41:28.320 --> 0:41:32.600
<v Speaker 1>you know, known pathologies affecting alcoholics. A royal commission in

0:41:32.680 --> 0:41:36.400
<v Speaker 1>Great Britain investigated the incident and discovered that the outbreak

0:41:36.440 --> 0:41:39.840
<v Speaker 1>of symptoms was due to contamination of these batches of

0:41:39.880 --> 0:41:44.359
<v Speaker 1>beer with the chemical element arsenic and known poison. Now,

0:41:44.480 --> 0:41:47.400
<v Speaker 1>given the isolation of this beer source, UH, and a

0:41:47.400 --> 0:41:51.240
<v Speaker 1>bit of historical analogy, finally a theory started to come together.

0:41:51.680 --> 0:41:56.160
<v Speaker 1>And it starts with beer foam and dish detergent. So

0:41:56.640 --> 0:41:58.879
<v Speaker 1>you ever seen a beer commercial on TV the kind

0:41:59.200 --> 0:42:01.440
<v Speaker 1>I know you've seen at least So sometimes you're you know,

0:42:01.440 --> 0:42:03.200
<v Speaker 1>you're hanging out by the pool party and with the

0:42:03.239 --> 0:42:07.040
<v Speaker 1>bottles or the cans. Right, sometimes you're a giant amid

0:42:07.080 --> 0:42:10.160
<v Speaker 1>the mountains and throwing the ball back and forth. Which

0:42:10.239 --> 0:42:12.640
<v Speaker 1>was the beer company that had the had the big

0:42:12.680 --> 0:42:15.920
<v Speaker 1>like Transformers monster. Oh, I don't know. See they all

0:42:16.000 --> 0:42:17.839
<v Speaker 1>they all couldn't run together for me. And I was never,

0:42:18.600 --> 0:42:21.600
<v Speaker 1>you know, a customer, but you know, sometimes you're partying

0:42:21.600 --> 0:42:24.920
<v Speaker 1>with a dog. Just About anything can happen in a

0:42:24.960 --> 0:42:27.840
<v Speaker 1>beer commercial, Okay, So I'm trying to get you to

0:42:27.880 --> 0:42:31.560
<v Speaker 1>picture a specific kind, which is the one where, uh,

0:42:31.640 --> 0:42:35.200
<v Speaker 1>somebody is pouring a nice frosty glass of beer straight

0:42:35.200 --> 0:42:38.040
<v Speaker 1>from the tap into a mug or or a pint

0:42:38.080 --> 0:42:40.600
<v Speaker 1>glass and handing it across the bar to the earthy

0:42:40.680 --> 0:42:43.719
<v Speaker 1>Marlboro man who's off work and ready to relax with

0:42:43.800 --> 0:42:46.919
<v Speaker 1>his friends. You know this kind, right with the bar,

0:42:47.080 --> 0:42:50.239
<v Speaker 1>with the glass, with especially the frothy head at the

0:42:50.280 --> 0:42:52.400
<v Speaker 1>top of the glass, right, and the Marlboro man is

0:42:52.400 --> 0:42:54.880
<v Speaker 1>going to drink from it, and he's gonna have the

0:42:54.880 --> 0:42:59.560
<v Speaker 1>foam stuck on his mustache. Yeah, got foam. Yeah. And

0:42:59.640 --> 0:43:02.319
<v Speaker 1>so in this genre of beer commercial, clearly one of

0:43:02.320 --> 0:43:05.080
<v Speaker 1>the most important is that equalities of that glass of

0:43:05.120 --> 0:43:07.839
<v Speaker 1>beer is the foamy top. Some people call it the head,

0:43:08.200 --> 0:43:11.360
<v Speaker 1>some people call it the collar. This foam is caused

0:43:11.400 --> 0:43:14.640
<v Speaker 1>by the quick rising of bubbles from previously dissolved gas.

0:43:14.719 --> 0:43:17.000
<v Speaker 1>Usually it's gonna be carbon dioxide, but I think some

0:43:17.040 --> 0:43:19.680
<v Speaker 1>brands actually dissolved nitrogen in there to help with the

0:43:19.719 --> 0:43:23.560
<v Speaker 1>foam guinness or some brands might do that. But these

0:43:23.600 --> 0:43:26.319
<v Speaker 1>bubbles form at nucleation points in the glass of beer

0:43:26.400 --> 0:43:28.600
<v Speaker 1>as it's poured, and they shoot up to the top

0:43:28.640 --> 0:43:30.960
<v Speaker 1>of the glass where they collect in a mesh of

0:43:31.160 --> 0:43:34.680
<v Speaker 1>bubbles and proteins from the malt in the beer and

0:43:34.840 --> 0:43:37.799
<v Speaker 1>bitter hop compounds. I was looking at an article that

0:43:37.880 --> 0:43:41.960
<v Speaker 1>interviewed a professor of biochemistry at Cornell named Carl Siebert

0:43:41.960 --> 0:43:45.120
<v Speaker 1>on the subject of what constitutes beer foam, and Siebert

0:43:45.120 --> 0:43:47.960
<v Speaker 1>mentioned that one of the important proteins in beer that

0:43:48.080 --> 0:43:51.160
<v Speaker 1>collects in these bubbles and this matrix of bubbles and

0:43:51.160 --> 0:43:54.120
<v Speaker 1>proteins in beer foam is albumen, which I thought I

0:43:54.120 --> 0:43:56.759
<v Speaker 1>would just add is also the same primary family of

0:43:56.760 --> 0:43:59.600
<v Speaker 1>proteins that you find in egg whites. So is there

0:43:59.640 --> 0:44:02.279
<v Speaker 1>something shared in common between your logger head and that

0:44:02.360 --> 0:44:05.440
<v Speaker 1>egg white omelet a little bit or your ramos gin fizz,

0:44:05.480 --> 0:44:07.560
<v Speaker 1>which of course is going to have that nice, creamy,

0:44:07.600 --> 0:44:10.680
<v Speaker 1>frothy consistency because of the egg whites that are part

0:44:10.719 --> 0:44:13.880
<v Speaker 1>of the recipe. Oh that's right, Yeah, But but in

0:44:13.920 --> 0:44:17.080
<v Speaker 1>the beer, like the head of the beer. I know

0:44:17.120 --> 0:44:18.799
<v Speaker 1>that you're not supposed to have too much of it, right,

0:44:18.880 --> 0:44:21.319
<v Speaker 1>Like that's a sign of a bad poor right. Yeah,

0:44:21.600 --> 0:44:24.040
<v Speaker 1>So I think it's widely agreed by beer drinkers that

0:44:24.120 --> 0:44:27.200
<v Speaker 1>a glass of beer without a correctly proportioned layer of

0:44:27.239 --> 0:44:30.080
<v Speaker 1>head is wrong. If you get too much head, if

0:44:30.080 --> 0:44:32.120
<v Speaker 1>it takes up like half the glass, or if you

0:44:32.160 --> 0:44:34.440
<v Speaker 1>have none at all, you have failed to beer. But

0:44:34.480 --> 0:44:36.640
<v Speaker 1>it's I'm assuming you still need a certain amount of

0:44:36.719 --> 0:44:38.920
<v Speaker 1>foam at the top for it just to feel like

0:44:38.960 --> 0:44:41.480
<v Speaker 1>you're drinking beer, right, And and the beer industry has

0:44:41.480 --> 0:44:44.480
<v Speaker 1>studied the chemistry of beer foam extensively to meet the

0:44:44.600 --> 0:44:48.040
<v Speaker 1>perceived customer demand for the right kind of frothy head

0:44:48.160 --> 0:44:51.279
<v Speaker 1>on a glass of beer. But the researchers Marin and

0:44:51.360 --> 0:44:55.280
<v Speaker 1>Daniel note that by the mid nineteen sixties, beer manufacturers

0:44:55.320 --> 0:44:59.239
<v Speaker 1>were encountering a problem that beer wasn't looking right in

0:44:59.280 --> 0:45:02.040
<v Speaker 1>a lot of ball ours. It didn't have that nice

0:45:02.080 --> 0:45:05.040
<v Speaker 1>frothy head that they believed the customers were looking for,

0:45:05.360 --> 0:45:07.680
<v Speaker 1>And this was believed to be the result of the

0:45:07.800 --> 0:45:12.279
<v Speaker 1>use of synthetic dishwashing detergents used to clean beer glasses,

0:45:12.680 --> 0:45:16.720
<v Speaker 1>which after cleaning and insufficient rinsing, would leave a layer

0:45:16.760 --> 0:45:19.560
<v Speaker 1>of film on the inside of the beer glass that

0:45:19.719 --> 0:45:23.360
<v Speaker 1>interfered with the beer's ability to foam up and create

0:45:23.400 --> 0:45:26.839
<v Speaker 1>a nice head. Interesting, I never thought about that. So

0:45:26.880 --> 0:45:31.960
<v Speaker 1>around July nine, some Canadian brewers and presumably brewers elsewhere

0:45:32.320 --> 0:45:36.600
<v Speaker 1>found a solution in modern chemistry in an additive chemical

0:45:36.680 --> 0:45:41.440
<v Speaker 1>compound that Marin and Daniel originally identify as cobalt sulfate,

0:45:41.800 --> 0:45:44.759
<v Speaker 1>but which later authors I think more correctly identified as

0:45:44.840 --> 0:45:48.319
<v Speaker 1>cobalt chloride. But the main thing here is that it's

0:45:48.320 --> 0:45:52.840
<v Speaker 1>a cobalt compound. This cobalt compound was added to draft

0:45:52.920 --> 0:45:57.719
<v Speaker 1>beer batches to stabilize the beer head and overcome any

0:45:57.840 --> 0:46:02.040
<v Speaker 1>anti foaming influence of deterred residue left in the beer glass.

0:46:02.360 --> 0:46:04.839
<v Speaker 1>So obviously we know where this is heading. But and

0:46:04.880 --> 0:46:07.760
<v Speaker 1>so it's probably coloring my judgment, but already it sounds

0:46:07.760 --> 0:46:11.680
<v Speaker 1>like if you're fighting detergent film, uh, through the food

0:46:11.719 --> 0:46:15.200
<v Speaker 1>product itself, through the beer itself, Like that's a bad sign,

0:46:15.520 --> 0:46:18.880
<v Speaker 1>right right uh? And and again this would be something

0:46:18.920 --> 0:46:21.239
<v Speaker 1>that they were only really supposed to be dealing with

0:46:21.360 --> 0:46:23.440
<v Speaker 1>through draft beer, right, And it's going to be poured

0:46:23.480 --> 0:46:26.200
<v Speaker 1>into a glass in a bar or something, it wouldn't

0:46:26.239 --> 0:46:28.759
<v Speaker 1>be the same in a bottle because you know the

0:46:28.840 --> 0:46:30.920
<v Speaker 1>number one, the head doesn't really matter in the bottle

0:46:30.920 --> 0:46:33.160
<v Speaker 1>as much. And then presumably that bottle is going to

0:46:33.200 --> 0:46:35.560
<v Speaker 1>be completely clean and not have any kind of like

0:46:35.640 --> 0:46:38.040
<v Speaker 1>you have control over what you're you're pre cleaning the

0:46:38.080 --> 0:46:40.920
<v Speaker 1>bottles with exactly. Yeah, But it turns out that at

0:46:40.960 --> 0:46:44.520
<v Speaker 1>least in this Quebec City brewery, this stuff was being

0:46:44.560 --> 0:46:48.320
<v Speaker 1>added to both the draft beer and the bottle beer

0:46:48.360 --> 0:46:51.120
<v Speaker 1>batches because they didn't make them separately. They made them

0:46:51.120 --> 0:46:53.279
<v Speaker 1>all in one batch and then split them up later.

0:46:54.040 --> 0:46:56.480
<v Speaker 1>So so they're putting cobalt in the beer. Wonder how

0:46:56.480 --> 0:46:59.640
<v Speaker 1>that's going to turn about. Let's talk about cobalt. Cobalt

0:46:59.719 --> 0:47:02.480
<v Speaker 1>is a amical element atomic number twenty seven. It's one

0:47:02.480 --> 0:47:06.040
<v Speaker 1>of the transition metals of the periodic table. It's essentially

0:47:06.120 --> 0:47:08.880
<v Speaker 1>never found in its pure form in nature. It's always

0:47:08.960 --> 0:47:12.640
<v Speaker 1>bound up with other elements in compounds and compound minerals

0:47:12.640 --> 0:47:17.120
<v Speaker 1>and other stuff. Very cool etymology fact. The English name

0:47:17.239 --> 0:47:22.319
<v Speaker 1>cobalt comes from the German word cobalt, which in its

0:47:22.440 --> 0:47:27.080
<v Speaker 1>general sense means goblin or imp or demon. More specifically,

0:47:27.560 --> 0:47:33.080
<v Speaker 1>it refers to a breed of German household or subterranean goblin. Uh,

0:47:33.400 --> 0:47:36.040
<v Speaker 1>there would be ones in your house, ones sometimes I

0:47:36.080 --> 0:47:40.200
<v Speaker 1>think in ships, and definitely in minds. And these goblins

0:47:40.200 --> 0:47:43.319
<v Speaker 1>could be full of tricks and mischief if you offended them.

0:47:43.480 --> 0:47:48.880
<v Speaker 1>So essentially, yes, So the cobalt or was rarely sought

0:47:48.880 --> 0:47:50.960
<v Speaker 1>out for its own sake at this time, but it

0:47:51.040 --> 0:47:54.600
<v Speaker 1>was usually a byproduct of mining for other metals like

0:47:54.719 --> 0:47:58.160
<v Speaker 1>silver or copper, and it seemed to some miners and

0:47:58.520 --> 0:48:01.759
<v Speaker 1>refiners and metal workers that this other element in the

0:48:01.760 --> 0:48:05.920
<v Speaker 1>ore carried impish or demonic qualities, since it was believed

0:48:05.960 --> 0:48:08.759
<v Speaker 1>to make workers sick with its fumes and degrade the

0:48:08.840 --> 0:48:12.400
<v Speaker 1>quality of silver. Now I think it seems, actually, with

0:48:12.480 --> 0:48:16.000
<v Speaker 1>historical perspective, that what was really making people sick during

0:48:16.000 --> 0:48:19.400
<v Speaker 1>this refining process was the arsenic content of the ore,

0:48:19.440 --> 0:48:23.920
<v Speaker 1>but the goblin name stuck with cobalt. Cobalt remains the

0:48:23.960 --> 0:48:28.040
<v Speaker 1>goblin metal. Cobalt was first chemically isolated in the seventeen

0:48:28.120 --> 0:48:31.239
<v Speaker 1>thirties by the Swedish chemist gae Org Bronte, but the

0:48:31.360 --> 0:48:34.640
<v Speaker 1>use of compounds containing cobalt goes back into the ancient world,

0:48:34.800 --> 0:48:37.000
<v Speaker 1>going back to our dye discussion, it appears that it

0:48:37.040 --> 0:48:39.960
<v Speaker 1>was often for the use of coloring. It was to

0:48:40.080 --> 0:48:44.160
<v Speaker 1>pigment or color statuettes in ancient Egypt, or beads in

0:48:44.200 --> 0:48:48.240
<v Speaker 1>ancient Persia, and cobalt was used in ceramics in China.

0:48:48.440 --> 0:48:51.719
<v Speaker 1>But what happens when you start eating or drinking it? Well,

0:48:51.920 --> 0:48:55.520
<v Speaker 1>Cobalt appears to have a very complex range of biological

0:48:55.560 --> 0:48:58.880
<v Speaker 1>effects at the same time, of course, it is not

0:48:59.040 --> 0:49:02.440
<v Speaker 1>a pure poise, and in fact, cobalt compounds in small

0:49:02.520 --> 0:49:05.560
<v Speaker 1>quantities are important for good health in a number of animals.

0:49:05.640 --> 0:49:08.040
<v Speaker 1>Or I said compounds plural, I think there's at least

0:49:08.080 --> 0:49:10.440
<v Speaker 1>one known one I can think of, which is vitamin

0:49:10.520 --> 0:49:14.480
<v Speaker 1>B twelve, also known as cobal aman. It contains cobalt

0:49:14.600 --> 0:49:16.880
<v Speaker 1>and UH and B twelve is of course essential for

0:49:16.920 --> 0:49:20.480
<v Speaker 1>good health. It sustains functions like cell metabolism, red blood

0:49:20.520 --> 0:49:23.680
<v Speaker 1>cell formation or the I think the maturation of red

0:49:23.680 --> 0:49:26.960
<v Speaker 1>blood cells, and in DNA synthesis. And in fact, there

0:49:27.000 --> 0:49:30.960
<v Speaker 1>were already by the nineteen sixties known therapeutic uses of cobalt.

0:49:31.440 --> 0:49:34.560
<v Speaker 1>But again, to revisit Paracelsis, it's the dose that makes

0:49:34.600 --> 0:49:38.080
<v Speaker 1>the poison. While some small amounts of some forms of

0:49:38.120 --> 0:49:41.680
<v Speaker 1>cobalt are necessary in the body. Humans are also extremely

0:49:41.760 --> 0:49:45.120
<v Speaker 1>sensitive to large doses of cobalt. So to come back

0:49:45.160 --> 0:49:48.360
<v Speaker 1>to the Quebec City outbreak in nineteen sixty five, according

0:49:48.400 --> 0:49:52.400
<v Speaker 1>to Morin and Daniel, the myocardial toxicity of cobalt was

0:49:52.520 --> 0:49:56.440
<v Speaker 1>already known to medical science in the nineteen sixties. Studies

0:49:56.480 --> 0:50:00.160
<v Speaker 1>had already shown that metabolized cobalt is deposited in the

0:50:00.239 --> 0:50:02.840
<v Speaker 1>muscle tissue of the heart and it will reduce the

0:50:02.840 --> 0:50:05.759
<v Speaker 1>ability of the heart muscles to contract, which of course

0:50:05.840 --> 0:50:08.719
<v Speaker 1>they need to do to pump blood. So the detectives

0:50:08.719 --> 0:50:11.720
<v Speaker 1>here looked into the timing of when cobalt was added

0:50:11.760 --> 0:50:14.560
<v Speaker 1>to the beer and the appearance of patients with beer

0:50:14.640 --> 0:50:18.319
<v Speaker 1>drinkers cardiomyopathy, and it was clear that the cobalt in

0:50:18.360 --> 0:50:21.279
<v Speaker 1>the beer was primarily to blame. After a pattern was

0:50:21.320 --> 0:50:25.160
<v Speaker 1>discovered in in nineteen sixty six, breweries in the United

0:50:25.200 --> 0:50:28.160
<v Speaker 1>States and Canada and elsewhere were ordered by their governments

0:50:28.200 --> 0:50:31.600
<v Speaker 1>to stop using cobalt additives, and this appears to have

0:50:31.719 --> 0:50:35.240
<v Speaker 1>stopped the the you know, people showing up at hospitals

0:50:35.239 --> 0:50:38.040
<v Speaker 1>and clinics with this unique type of cardio myopathy. In

0:50:38.040 --> 0:50:41.759
<v Speaker 1>the following months. Robert, I've attached a little timeline for

0:50:41.840 --> 0:50:44.840
<v Speaker 1>you here being see quite clearly a pattern where basically

0:50:44.880 --> 0:50:48.480
<v Speaker 1>the cobalt is introduced and then the patients start showing up,

0:50:48.800 --> 0:50:51.600
<v Speaker 1>the cobalt is removed, and the patients stopped showing up.

0:50:51.760 --> 0:50:54.279
<v Speaker 1>Oh yeah, it is a there's a clear correlation there. Now,

0:50:54.320 --> 0:50:57.120
<v Speaker 1>there are some peculiarities here, and one is that in

0:50:57.239 --> 0:51:00.040
<v Speaker 1>both the case of the nineteen hundred beer poise in

0:51:00.360 --> 0:51:04.520
<v Speaker 1>England and the outbreaks of beer drinkers cardiomyopathy, it seemed

0:51:04.600 --> 0:51:07.080
<v Speaker 1>like at least some patients, maybe a lot of patients,

0:51:07.160 --> 0:51:11.040
<v Speaker 1>displayed symptoms that were more powerful than you would expect

0:51:11.480 --> 0:51:15.520
<v Speaker 1>from the doses of arsenic and cobalt alone, respectively, that

0:51:15.600 --> 0:51:18.520
<v Speaker 1>they received. So it also looks like the negative effects

0:51:18.520 --> 0:51:23.040
<v Speaker 1>of alcoholism, along with poor diet and nutrition, maybe contributing

0:51:23.120 --> 0:51:26.920
<v Speaker 1>to making the arsenic and the cobalt more potent poisons

0:51:26.960 --> 0:51:29.640
<v Speaker 1>than they would have been on their own. Nevertheless, I

0:51:29.680 --> 0:51:32.720
<v Speaker 1>think it's totally clear that the cobalt was primarily the cause.

0:51:33.320 --> 0:51:36.720
<v Speaker 1>Uh and Moren and Daniel also add a really stern,

0:51:37.160 --> 0:51:40.719
<v Speaker 1>pretty harsh addendum to their paper. Uh. They point out

0:51:40.760 --> 0:51:43.799
<v Speaker 1>that the a chelating agent called E d t A

0:51:44.000 --> 0:51:48.040
<v Speaker 1>quote has been shown to prevent cobalt intoxication in the animal.

0:51:48.520 --> 0:51:50.959
<v Speaker 1>Had this metal been known to be present in beer

0:51:51.000 --> 0:51:53.920
<v Speaker 1>at the time of the epidemic, the prompt administration of

0:51:54.000 --> 0:51:56.640
<v Speaker 1>E d t A might have saved some of our patients.

0:51:57.000 --> 0:52:00.040
<v Speaker 1>The clinician, accustomed to knowing the exact composition of the

0:52:00.120 --> 0:52:04.040
<v Speaker 1>drugs he uses, will therefore seriously question the necessity for

0:52:04.120 --> 0:52:07.400
<v Speaker 1>the secrecy that surrounds the use of food or drink additives.

0:52:07.840 --> 0:52:09.960
<v Speaker 1>That makes sense again, It comes back to to to

0:52:10.040 --> 0:52:13.000
<v Speaker 1>the the fact that in the modern world we have

0:52:13.080 --> 0:52:16.400
<v Speaker 1>such a robust palette from which to create our various

0:52:16.400 --> 0:52:20.240
<v Speaker 1>food products. Uh. Well, if you're going to be treating

0:52:20.440 --> 0:52:23.120
<v Speaker 1>an illness that maybe due to your particular food or

0:52:23.160 --> 0:52:26.960
<v Speaker 1>drink product, you need to have the secret ingredients fully

0:52:26.960 --> 0:52:31.239
<v Speaker 1>listed so that medical personnel can respond appropriately. Yeah. And

0:52:31.400 --> 0:52:33.919
<v Speaker 1>I mean it's known here that they're saying, if we'd

0:52:33.960 --> 0:52:36.879
<v Speaker 1>known about the cobalt earlier, some people who died might

0:52:36.920 --> 0:52:42.000
<v Speaker 1>have lived. Uh. That's a tragic reality. Um, that's just

0:52:42.080 --> 0:52:44.520
<v Speaker 1>that seems to be this unfortunate side effect of the

0:52:44.520 --> 0:52:48.040
<v Speaker 1>the idea of protecting recipes and industrial secrets and stuff.

0:52:48.840 --> 0:52:52.000
<v Speaker 1>But anyway, after the link between the cobalt additive and

0:52:52.000 --> 0:52:55.040
<v Speaker 1>the cardiac disease was discovered, the use of cobalt, of

0:52:55.080 --> 0:52:57.759
<v Speaker 1>course was suspended, as we said, but there must have

0:52:57.840 --> 0:53:01.640
<v Speaker 1>been plenty of cases around the world of undiagnosed cobalt

0:53:01.719 --> 0:53:06.160
<v Speaker 1>cardio myopathy which doctors just mistook for more common forms

0:53:06.200 --> 0:53:10.160
<v Speaker 1>of heart disease. Eves Moren emphasizes this point speaking to

0:53:10.200 --> 0:53:14.799
<v Speaker 1>the CBC in article about the cobalt poisoning quote, you

0:53:14.840 --> 0:53:17.839
<v Speaker 1>can't imagine the number of patients everywhere who died from

0:53:17.880 --> 0:53:22.240
<v Speaker 1>that disease because it wast mortality. But the story doesn't

0:53:22.280 --> 0:53:26.160
<v Speaker 1>in there. I was reading article from the CBC, uh

0:53:26.200 --> 0:53:28.000
<v Speaker 1>that was the one I just cited, and and the

0:53:28.040 --> 0:53:31.200
<v Speaker 1>occasion of this article was that there was another case

0:53:31.280 --> 0:53:34.279
<v Speaker 1>of cobalt poisoning that was recognized by a group of

0:53:34.320 --> 0:53:36.920
<v Speaker 1>doctors in Germany that year with the help of an

0:53:36.920 --> 0:53:40.720
<v Speaker 1>episode of the TV show House, which I've never seen before,

0:53:40.800 --> 0:53:44.320
<v Speaker 1>but apparently the doctor said the fact that cobalt poisoning

0:53:44.600 --> 0:53:47.120
<v Speaker 1>had showed up on an episode of the TV show

0:53:47.680 --> 0:53:50.920
<v Speaker 1>led them to along with the this historical case of

0:53:50.960 --> 0:53:54.520
<v Speaker 1>the beer outbreak in the sixties led them to diagnose

0:53:54.640 --> 0:53:58.040
<v Speaker 1>correctly what was happening to fifty five year old man

0:53:58.080 --> 0:54:00.600
<v Speaker 1>who showed up in a hospital in Marburg, Germany with

0:54:00.680 --> 0:54:06.520
<v Speaker 1>severe heart failure, deafness, blindness, fever, hypothyroidism, and swollen lymph nodes,

0:54:07.040 --> 0:54:10.040
<v Speaker 1>and the doctors eventually pinpointed the cause of his sudden illness,

0:54:10.080 --> 0:54:14.560
<v Speaker 1>which was cobalt poisoning from metal hip implants. A common

0:54:14.680 --> 0:54:18.760
<v Speaker 1>use of cobalt today is in is in special like alloy,

0:54:18.920 --> 0:54:23.760
<v Speaker 1>is like magnetic metals and alloys. And apparently this patient

0:54:23.840 --> 0:54:27.480
<v Speaker 1>had I think part of some kind of ceramic object

0:54:27.880 --> 0:54:30.840
<v Speaker 1>with part of it with his hip replacement rubbing against

0:54:30.840 --> 0:54:34.080
<v Speaker 1>the metal alloy element of the hip replacement, and it

0:54:34.200 --> 0:54:38.560
<v Speaker 1>was the rubbing was releasing cobalt into his bloodstream. But

0:54:38.800 --> 0:54:41.239
<v Speaker 1>the doctors figured this out. The patient had his hip

0:54:41.280 --> 0:54:44.320
<v Speaker 1>pros thesis removed and replaced with a new model, after

0:54:44.360 --> 0:54:47.280
<v Speaker 1>which the concentrations of cobalt and chromium and his blood

0:54:47.280 --> 0:54:50.040
<v Speaker 1>decreased and he recovered from some of the worst of

0:54:50.080 --> 0:54:52.879
<v Speaker 1>his symptoms, but not immediately from all of them. Well

0:54:52.880 --> 0:54:56.319
<v Speaker 1>that's that's that's very interesting, And as far as house goes,

0:54:56.520 --> 0:54:59.200
<v Speaker 1>I've never watched either left the lead actor, but this

0:54:59.280 --> 0:55:02.360
<v Speaker 1>is a great example of why it's it's not a

0:55:02.400 --> 0:55:05.080
<v Speaker 1>bad thing to get the science at least mostly right

0:55:05.880 --> 0:55:09.520
<v Speaker 1>in some sort of popular form of entertainment, because people

0:55:09.520 --> 0:55:12.080
<v Speaker 1>are going to you know, they're going to learn from

0:55:12.120 --> 0:55:14.839
<v Speaker 1>it for better or worse, you know. And here's an

0:55:14.880 --> 0:55:17.560
<v Speaker 1>example of of of them getting the science right or

0:55:17.560 --> 0:55:21.720
<v Speaker 1>even mostly right, helped investigators go in the right direction

0:55:21.719 --> 0:55:24.080
<v Speaker 1>on this particular case. Yeah, but I think this is

0:55:24.160 --> 0:55:27.480
<v Speaker 1>such a bizarre and fascinating story, going from like the

0:55:27.520 --> 0:55:30.840
<v Speaker 1>aesthetics of what beer looks like in a glass to

0:55:30.840 --> 0:55:35.240
<v Speaker 1>to these outbreaks of metal poisoning. Yeah, yeah, and and

0:55:35.120 --> 0:55:37.200
<v Speaker 1>and like and again it's clearly a case where the

0:55:37.200 --> 0:55:39.560
<v Speaker 1>the individuals who did this, they were they were thinking, well,

0:55:39.600 --> 0:55:41.400
<v Speaker 1>we just we want to make the beer look nicer.

0:55:41.440 --> 0:55:44.479
<v Speaker 1>What can we add. Here's something that that we can add,

0:55:44.520 --> 0:55:47.000
<v Speaker 1>and it's gonna it's not gonna hurt anybody like that

0:55:47.120 --> 0:55:50.480
<v Speaker 1>was clearly far from their minds. And uh, and yet

0:55:50.560 --> 0:55:54.040
<v Speaker 1>these were the unforeseen consequences. But again that's the complexity

0:55:54.200 --> 0:55:57.640
<v Speaker 1>of of of food in our modern world of processed

0:55:57.719 --> 0:56:01.000
<v Speaker 1>food and and and certainly beer is as a as

0:56:01.000 --> 0:56:04.040
<v Speaker 1>an artificial product, it is processed. I mean, it's stories

0:56:04.120 --> 0:56:07.840
<v Speaker 1>like this that can make you. Normally you don't stop

0:56:07.880 --> 0:56:11.680
<v Speaker 1>to to appreciate the bureaucrats, but it's stories like this

0:56:11.719 --> 0:56:14.120
<v Speaker 1>can that can really make you say, like, hey, wow,

0:56:14.160 --> 0:56:18.120
<v Speaker 1>it's it's actually amazing that that modern societies have come

0:56:18.200 --> 0:56:20.719
<v Speaker 1>up with things like food and drug testing organize, you know,

0:56:20.719 --> 0:56:23.840
<v Speaker 1>like a Food and Drug Administration or something that looks

0:56:23.960 --> 0:56:26.480
<v Speaker 1>at products that are going out to mass markets in

0:56:26.520 --> 0:56:29.120
<v Speaker 1>an organized way to say, can we be pretty certain

0:56:29.200 --> 0:56:32.239
<v Speaker 1>that this is safe before releasing it on the public, right,

0:56:32.280 --> 0:56:34.479
<v Speaker 1>We didn't always have that. I mean, yeah, it's easy

0:56:34.480 --> 0:56:36.560
<v Speaker 1>to say, you know, I don't want the government. You know,

0:56:36.560 --> 0:56:38.720
<v Speaker 1>I'm saying what I can and can't put in my body.

0:56:38.760 --> 0:56:41.000
<v Speaker 1>But if the thing we're talking about is a say,

0:56:41.040 --> 0:56:44.920
<v Speaker 1>a lead laced UH sucker for a child, or or

0:56:45.080 --> 0:56:49.600
<v Speaker 1>or or a cobalt infused beer, you don't necessarily know

0:56:49.640 --> 0:56:52.080
<v Speaker 1>what you're putting in your body hasn't been tested. I'm

0:56:52.360 --> 0:56:56.920
<v Speaker 1>all for big Brother jumping in and weeding out you know,

0:56:57.000 --> 0:56:59.920
<v Speaker 1>poisonous products like that, but that's just me. You may

0:57:00.000 --> 0:57:03.680
<v Speaker 1>have a different opinion of poison. So anyway, I don't

0:57:03.680 --> 0:57:05.520
<v Speaker 1>know if this was going to really help anybody out

0:57:05.600 --> 0:57:10.360
<v Speaker 1>this Thanksgiving uh don't don't put cobalt on your turkey,

0:57:10.600 --> 0:57:14.640
<v Speaker 1>right right, You don't just don't use any like hard

0:57:14.960 --> 0:57:19.600
<v Speaker 1>heavy metals to to flavor or way down anything. But

0:57:19.720 --> 0:57:21.720
<v Speaker 1>I don't know. I guess in general, you know, you're

0:57:21.760 --> 0:57:25.720
<v Speaker 1>going to use some processed foods during you know, whatever

0:57:25.800 --> 0:57:28.000
<v Speaker 1>kind of feast you might be having, You're going to

0:57:28.200 --> 0:57:30.640
<v Speaker 1>use additives or something that has additives added to it.

0:57:30.880 --> 0:57:33.480
<v Speaker 1>And so it is I think inciple to understand the

0:57:33.760 --> 0:57:37.120
<v Speaker 1>history of these things, and uh and the Carol careful

0:57:37.160 --> 0:57:41.120
<v Speaker 1>balance that is in play between you know, finding a

0:57:41.200 --> 0:57:45.200
<v Speaker 1>nice color, enhancing a flavor, and potentially poisoning somebody. Can

0:57:45.240 --> 0:57:47.800
<v Speaker 1>we end with just a food coloring tip. Sure, you

0:57:47.880 --> 0:57:51.200
<v Speaker 1>sort of mentioned earlier when you were listing natural foods

0:57:51.280 --> 0:57:55.160
<v Speaker 1>that are sometimes used for their their dying properties or pigments.

0:57:55.520 --> 0:57:58.200
<v Speaker 1>One that I think is a great substitute for saffron.

0:57:58.240 --> 0:58:00.120
<v Speaker 1>It doesn't get the flavor there, but it all so

0:58:00.200 --> 0:58:03.120
<v Speaker 1>creates a wonderful yellow orange hue is just use a

0:58:03.120 --> 0:58:05.960
<v Speaker 1>little bit of turmeric. You don't have saffron at the house,

0:58:06.000 --> 0:58:08.520
<v Speaker 1>but you want to make a nice yellow pot of rice,

0:58:08.600 --> 0:58:10.080
<v Speaker 1>a little bit of turmeric in there. It goes a

0:58:10.080 --> 0:58:13.439
<v Speaker 1>long way. Oh, yeah, I love I love turmeric. All right, Well,

0:58:13.480 --> 0:58:15.439
<v Speaker 1>we're gonna go ahead and call it here for this

0:58:15.560 --> 0:58:18.520
<v Speaker 1>year's Dangerous Foods. But I think I think we'll probably

0:58:18.480 --> 0:58:21.400
<v Speaker 1>be back next year with another Dangerous Foods episode. We

0:58:21.440 --> 0:58:26.520
<v Speaker 1>did not exhaust the the larder of poisons this time,

0:58:27.120 --> 0:58:28.760
<v Speaker 1>so I think we'll be able to come back with

0:58:28.800 --> 0:58:31.200
<v Speaker 1>some new angle next year. In the meantime, if you

0:58:31.240 --> 0:58:32.800
<v Speaker 1>want to check out more episodes of Stuff to Blow

0:58:32.840 --> 0:58:34.960
<v Speaker 1>your Mind, going over to stuff to Blow your Mind

0:58:34.960 --> 0:58:36.960
<v Speaker 1>dot com. That's where we will find them. That's the mothership,

0:58:37.520 --> 0:58:39.320
<v Speaker 1>and you can also find the show wherever you get

0:58:39.360 --> 0:58:41.360
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0:58:41.440 --> 0:58:44.320
<v Speaker 1>subscribed and give us a rating and review. That really

0:58:44.320 --> 0:58:47.280
<v Speaker 1>helps us out. If you want a little horror fiction,

0:58:47.400 --> 0:58:49.560
<v Speaker 1>check out the second Oil Aige that's out wherever you

0:58:49.600 --> 0:58:52.000
<v Speaker 1>get your podcast. You can also check out our other

0:58:52.640 --> 0:58:56.840
<v Speaker 1>nonfiction show that Being Invention. Invention is a journey through

0:58:56.920 --> 0:59:01.080
<v Speaker 1>human techno history, one invention at a time. UH. This month,

0:59:01.200 --> 0:59:03.200
<v Speaker 1>there have been a number of food episodes, a two

0:59:03.200 --> 0:59:06.240
<v Speaker 1>part look at the microwave. For instance, use a microwave

0:59:06.280 --> 0:59:08.840
<v Speaker 1>every day? Do you know how it works? Well? You

0:59:08.840 --> 0:59:11.160
<v Speaker 1>should listen to these episodes and make sure you're on

0:59:11.240 --> 0:59:14.320
<v Speaker 1>top of that. Uh, let's see what else? Oh yeah.

0:59:14.320 --> 0:59:17.960
<v Speaker 1>On on the social media, there's the Facebook group the

0:59:17.960 --> 0:59:19.760
<v Speaker 1>Stuff to Blow Your Mind discussion module. That's a good

0:59:19.760 --> 0:59:22.360
<v Speaker 1>place to to chime in and chat with other listeners.

0:59:22.360 --> 0:59:23.920
<v Speaker 1>I'm sure some folks are going to shi m in

0:59:23.920 --> 0:59:27.040
<v Speaker 1>about Strange Brew too, and to let everyone know exactly

0:59:27.040 --> 0:59:29.520
<v Speaker 1>what that film is about and what extent it may

0:59:29.600 --> 0:59:32.240
<v Speaker 1>or may not tie into our topics today. Do you

0:59:32.320 --> 0:59:34.760
<v Speaker 1>have Rick Moranis in it? Yeah? I was just getting

0:59:34.800 --> 0:59:38.280
<v Speaker 1>Rick Moranis and uh, the other guy from was this

0:59:38.360 --> 0:59:42.480
<v Speaker 1>was the Second City, Dave Thomas. Dave Thomas, Dave Thomas, Yes,

0:59:42.800 --> 0:59:46.439
<v Speaker 1>Dave Thomas, Rick Moranis and probably some other names as well,

0:59:46.480 --> 0:59:48.800
<v Speaker 1>but those are the two leads. Uh. I just want

0:59:48.800 --> 0:59:51.320
<v Speaker 1>to emphasize again if you haven't checked out Invention yet,

0:59:51.360 --> 0:59:53.160
<v Speaker 1>check that out. If you haven't checked out the second

0:59:53.160 --> 0:59:55.280
<v Speaker 1>oil age, you must do it. I think you're gonna

0:59:55.360 --> 0:59:58.080
<v Speaker 1>love it. It's so much fun. Oh and T shirts

0:59:58.640 --> 1:00:01.240
<v Speaker 1>The Stuff to Blow Your Mind of merch store is

1:00:01.280 --> 1:00:04.040
<v Speaker 1>still active and i'd just mind understanding that there is

1:00:04.080 --> 1:00:06.200
<v Speaker 1>a new shirt in there for Thanksgiving and there is

1:00:06.240 --> 1:00:09.240
<v Speaker 1>also some manner of like there's like you know, there's

1:00:09.240 --> 1:00:13.120
<v Speaker 1>always Black Friday feels and Thanksgiving deals, so just be

1:00:13.200 --> 1:00:16.120
<v Speaker 1>advised this is a good time to get merchandise from

1:00:16.160 --> 1:00:19.000
<v Speaker 1>that store if you so desire. Totally by it all

1:00:19.720 --> 1:00:23.000
<v Speaker 1>huge thanks as always to our excellent audio producer Seth

1:00:23.080 --> 1:00:25.560
<v Speaker 1>Nicholas Johnson. If you would like to get in touch

1:00:25.560 --> 1:00:27.800
<v Speaker 1>with us with feedback on this episode or any other,

1:00:27.880 --> 1:00:30.760
<v Speaker 1>to suggest topic for the future, or just to say hello,

1:00:30.880 --> 1:00:34.000
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1:00:34.040 --> 1:00:43.440
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1:00:43.440 --> 1:00:45.760
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