1 00:00:00,560 --> 00:00:03,760 Speaker 1: Welcome to Stuff you missed in history class from how 2 00:00:03,800 --> 00:00:13,600 Speaker 1: Stuff Works dot com. Hello, and welcome to the podcast. 3 00:00:13,600 --> 00:00:15,560 Speaker 1: I'm to Blane a chalk reboarding and I'm scared out. 4 00:00:16,040 --> 00:00:18,400 Speaker 1: And even if you're not a science person at all, 5 00:00:18,480 --> 00:00:21,439 Speaker 1: you probably know something about d N A. That's stuff 6 00:00:21,480 --> 00:00:24,800 Speaker 1: in our cells that carries the cells genetic information and 7 00:00:24,840 --> 00:00:29,560 Speaker 1: basically determines all of our individual hereditary characteristics, hair color, 8 00:00:29,560 --> 00:00:32,320 Speaker 1: eye color, the whole deal. So if you watch TV, 9 00:00:32,520 --> 00:00:35,239 Speaker 1: you probably know at least that much. But most of 10 00:00:35,280 --> 00:00:37,640 Speaker 1: us probably have at least touched on the subject in 11 00:00:37,720 --> 00:00:40,480 Speaker 1: high school too, or will touch on it in high school, 12 00:00:40,640 --> 00:00:43,239 Speaker 1: not to rule out our younger listeners. And we can 13 00:00:43,320 --> 00:00:47,479 Speaker 1: recognize what DNA looks like, that unmistakable double helix that 14 00:00:47,520 --> 00:00:50,680 Speaker 1: looks like a twisting ladder or a spiral staircase. I 15 00:00:50,720 --> 00:00:54,440 Speaker 1: remember actually modeling it in middle school cleaners, So maybe 16 00:00:54,480 --> 00:00:58,640 Speaker 1: some of our younger listeners already knew well. The people 17 00:00:58,680 --> 00:01:01,720 Speaker 1: credited in most high school in middle school textbooks, at 18 00:01:01,760 --> 00:01:04,080 Speaker 1: least when I was in school, which admittedly was a 19 00:01:04,160 --> 00:01:07,600 Speaker 1: while ago. Um, the people credited with discovering the structure 20 00:01:07,600 --> 00:01:11,080 Speaker 1: of DNA are James Watson and Francis Crick. That's one 21 00:01:11,120 --> 00:01:13,399 Speaker 1: of those associations that kind of has stuck in my 22 00:01:13,440 --> 00:01:15,600 Speaker 1: mind over the years. You know, it's like Darwin and 23 00:01:16,120 --> 00:01:19,960 Speaker 1: natural selection and Watson and Crick in DNA. And after all, 24 00:01:20,080 --> 00:01:22,760 Speaker 1: they along with Maurice Wilkins, received the Nobel Prize in 25 00:01:22,800 --> 00:01:25,319 Speaker 1: Medicine for this discovery in nineteen sixty two, so it 26 00:01:25,360 --> 00:01:28,000 Speaker 1: makes sense that their names would be most associated with 27 00:01:28,040 --> 00:01:31,720 Speaker 1: this accomplishment. But especially in recent years, some more attention 28 00:01:31,720 --> 00:01:33,840 Speaker 1: has been paid to someone else who may deserve a 29 00:01:33,840 --> 00:01:36,480 Speaker 1: great deal of the credit for the discovery of DNA structure, 30 00:01:36,840 --> 00:01:40,520 Speaker 1: and that's a British physical chemist named Rosalind Franklin. So 31 00:01:40,800 --> 00:01:44,960 Speaker 1: Franklin's involvement in this DNA discovery has caused quite a 32 00:01:45,040 --> 00:01:48,240 Speaker 1: bit of controversy in the science world for a number 33 00:01:48,280 --> 00:01:52,000 Speaker 1: of reasons. So number one, it's without question that her 34 00:01:52,040 --> 00:01:55,280 Speaker 1: research played a really big role in helping suff out 35 00:01:55,360 --> 00:01:59,000 Speaker 1: DNA structure. But because she died four years before Watson, 36 00:01:59,040 --> 00:02:02,800 Speaker 1: Crick and wilk And even received the Nobel Prize, the 37 00:02:02,920 --> 00:02:06,800 Speaker 1: prize only honors living scientists. So she said for this year, 38 00:02:06,880 --> 00:02:08,720 Speaker 1: except for the year, except for this year, there was 39 00:02:08,880 --> 00:02:11,639 Speaker 1: Ralph Steinman. Did you hear about that he won the 40 00:02:11,680 --> 00:02:14,520 Speaker 1: prize for medicine, and I think the announcement was made 41 00:02:15,000 --> 00:02:17,880 Speaker 1: three days after his death. So they went ahead, and 42 00:02:18,000 --> 00:02:20,240 Speaker 1: they went ahead and let it stand because they had 43 00:02:20,280 --> 00:02:22,280 Speaker 1: made the decision before they even knew he was dead. 44 00:02:22,360 --> 00:02:26,880 Speaker 1: So so well then up until then. So yeah, they 45 00:02:27,080 --> 00:02:31,200 Speaker 1: are more associated with it because they won the award 46 00:02:31,240 --> 00:02:34,560 Speaker 1: for it, and Watson and Crick's famous nineteen fifty three 47 00:02:34,560 --> 00:02:37,880 Speaker 1: paper detailing their discoveries in the journal Nature, they only 48 00:02:37,960 --> 00:02:43,320 Speaker 1: gave Franklin the tiniest credit, and so consequently she's virtually 49 00:02:43,440 --> 00:02:46,680 Speaker 1: or has been virtually unknown for this accomplishment. That's the 50 00:02:46,720 --> 00:02:50,320 Speaker 1: second reason, and then the third is in his nineteen 51 00:02:50,400 --> 00:02:53,919 Speaker 1: sixty eight but chronicling the discovery called the double helix 52 00:02:53,960 --> 00:02:58,640 Speaker 1: appropriately enough, Watson noted the role Franklin's research played and 53 00:02:58,760 --> 00:03:03,880 Speaker 1: also revealed that it played a role without Franklin's knowledge. 54 00:03:03,960 --> 00:03:06,720 Speaker 1: That's a pretty big one there, sketchy, So you can 55 00:03:06,760 --> 00:03:09,840 Speaker 1: see where the controversy comes in. This revelation raised a 56 00:03:09,960 --> 00:03:14,000 Speaker 1: number of questions. For instance, did Watson and Crick steal 57 00:03:14,160 --> 00:03:18,400 Speaker 1: Franklin's research And if they didn't, would she have figured 58 00:03:18,440 --> 00:03:20,840 Speaker 1: it out? Would she have figured out DNA structure on 59 00:03:20,880 --> 00:03:23,560 Speaker 1: her own. So we're going to address these questions and 60 00:03:23,639 --> 00:03:25,560 Speaker 1: more as we take a look at what really went 61 00:03:25,560 --> 00:03:28,320 Speaker 1: down in England in nineteen fifty three when this particular 62 00:03:28,360 --> 00:03:31,320 Speaker 1: discovery was made. But first we're going to take a 63 00:03:31,360 --> 00:03:35,200 Speaker 1: look at another relevant question here. Who was Rosalind Franklin 64 00:03:35,280 --> 00:03:39,119 Speaker 1: really So in Watson's book The Double Helix, he kind 65 00:03:39,120 --> 00:03:42,520 Speaker 1: of dissed Franklin a little bit, basically depicted her as 66 00:03:42,600 --> 00:03:46,280 Speaker 1: stubborn and hard to work with, an unfeminine, but other 67 00:03:46,320 --> 00:03:49,800 Speaker 1: people who knew her really characterized her in a different way. 68 00:03:50,240 --> 00:03:53,240 Speaker 1: What we do know personality aside, is that she had 69 00:03:53,280 --> 00:03:56,560 Speaker 1: a passion for science from the very start. She was 70 00:03:56,640 --> 00:04:01,840 Speaker 1: born Rosalind Elsie Franklin in London, England, on July twenty 71 00:04:01,960 --> 00:04:05,400 Speaker 1: and of course, most girls around that time were expected 72 00:04:05,520 --> 00:04:09,520 Speaker 1: to have very few goals outside of becoming successful wives 73 00:04:09,560 --> 00:04:14,880 Speaker 1: and mothers, but Franklin's parents, Ellis Franklin and Muriel Walie Franklin, 74 00:04:15,280 --> 00:04:19,680 Speaker 1: were more progressive and really encouraged their daughter academically. They 75 00:04:19,760 --> 00:04:23,240 Speaker 1: even enrolled young Franklin in the St. Paul's School for Girls, 76 00:04:23,279 --> 00:04:25,640 Speaker 1: which was one of the few schools at the time 77 00:04:25,680 --> 00:04:29,840 Speaker 1: that offered physics and chemistry. Lessons to female students, and 78 00:04:29,960 --> 00:04:33,200 Speaker 1: Franklin really excelled in these courses, and she decided by 79 00:04:33,240 --> 00:04:35,400 Speaker 1: the age of fifteen that she really wanted a career 80 00:04:35,400 --> 00:04:38,719 Speaker 1: in science, even though her parents wanted her to pursue 81 00:04:38,839 --> 00:04:42,200 Speaker 1: social work instead. So she enrolled Newnham College at the 82 00:04:42,240 --> 00:04:45,040 Speaker 1: University of Cambridge in nineteen thirty eight and was one 83 00:04:45,080 --> 00:04:47,360 Speaker 1: of only five hundred women in a class of more 84 00:04:47,360 --> 00:04:50,640 Speaker 1: than five thousand. She earned a bachelor's degree in natural 85 00:04:50,640 --> 00:04:54,200 Speaker 1: sciences with a specialty in physical chemistry in nineteen forty one. 86 00:04:54,720 --> 00:04:56,839 Speaker 1: And we should stop here for just one second, when 87 00:04:56,880 --> 00:05:01,159 Speaker 1: we have noted her scientific achievements or her initial ones, 88 00:05:01,400 --> 00:05:03,440 Speaker 1: to give a little disclaimer and say that we are 89 00:05:03,480 --> 00:05:05,919 Speaker 1: not scientists here and do not have degrees in science. 90 00:05:05,960 --> 00:05:08,080 Speaker 1: So we're going to be kind of vague about some 91 00:05:08,160 --> 00:05:11,360 Speaker 1: of the concepts that we explain here, and hopefully listeners 92 00:05:11,400 --> 00:05:13,800 Speaker 1: will forgive us for that well. And part of it, too, 93 00:05:13,920 --> 00:05:17,239 Speaker 1: is to focus on the people involved and the story involved, 94 00:05:17,279 --> 00:05:19,479 Speaker 1: because story sometimes if you get too bogged down in 95 00:05:19,520 --> 00:05:21,560 Speaker 1: the other details, you miss out on some of them. 96 00:05:21,640 --> 00:05:24,359 Speaker 1: Y'all can easily find out scientific details on this, So 97 00:05:24,440 --> 00:05:27,960 Speaker 1: continuing on with Franklin's life, After earning her bachelor's degree, 98 00:05:28,040 --> 00:05:31,280 Speaker 1: she got a research scholarship in the study of gas 99 00:05:31,279 --> 00:05:36,280 Speaker 1: phase chromatography with the chemist Ronald G. W. Norrish, who 100 00:05:36,360 --> 00:05:40,200 Speaker 1: was a future Nobel Prize winner himself. But the progression 101 00:05:40,200 --> 00:05:42,760 Speaker 1: of World War Two and the fact that Franklin found 102 00:05:42,760 --> 00:05:45,919 Speaker 1: Nourish kind of difficult to work with changed her course 103 00:05:45,960 --> 00:05:49,080 Speaker 1: of study a little bit. According to Encyclopedia Britannica, she 104 00:05:49,480 --> 00:05:52,880 Speaker 1: served as an air raid warden in London and also 105 00:05:53,400 --> 00:05:56,160 Speaker 1: left her job with Nourish in nineteen forty two to 106 00:05:56,279 --> 00:05:59,719 Speaker 1: do war related work as a researcher with the British 107 00:06:00,320 --> 00:06:05,560 Speaker 1: Utilization Research Association. That's kind of a mouthful in southern England, 108 00:06:05,760 --> 00:06:08,520 Speaker 1: and while she was there she worked on studying the 109 00:06:08,520 --> 00:06:12,160 Speaker 1: physical chemistry of carbon and coal, and the work she 110 00:06:12,240 --> 00:06:16,760 Speaker 1: did ultimately led to some really enlightening ideas about coal structure, 111 00:06:16,800 --> 00:06:19,640 Speaker 1: so a little bit of foreshadowing almost of of work 112 00:06:19,720 --> 00:06:22,359 Speaker 1: she'd do later. She also learned the basics of molecular 113 00:06:22,360 --> 00:06:25,160 Speaker 1: biology and crystallography while she was there, and her work 114 00:06:25,200 --> 00:06:29,400 Speaker 1: earned her a PhD from Cambridge in nineteen She also 115 00:06:29,480 --> 00:06:33,200 Speaker 1: authored five coal related papers they're still sited today before 116 00:06:33,320 --> 00:06:36,760 Speaker 1: nineteen forty nine, according to an article by Lynn Osmond 117 00:06:36,760 --> 00:06:40,320 Speaker 1: Elkin in Physics Today, Franklin's papers quote changed the way 118 00:06:40,360 --> 00:06:43,120 Speaker 1: physical chemists of view the micro structure of coals and 119 00:06:43,160 --> 00:06:48,000 Speaker 1: related substances. So Franklin's work, in addition to getting some 120 00:06:48,120 --> 00:06:52,599 Speaker 1: praise by current scientists, got her another job offer. In 121 00:06:52,680 --> 00:06:55,279 Speaker 1: nineteen seven, she moved to Paris to work at the 122 00:06:55,320 --> 00:07:00,240 Speaker 1: Central Laboratory of Chemical Services, where under Jacques Marrying, she 123 00:07:00,480 --> 00:07:03,800 Speaker 1: learned to use a technique called X ray diffraction when 124 00:07:03,839 --> 00:07:07,320 Speaker 1: working with crystalline matter like coal. And just to give 125 00:07:07,360 --> 00:07:10,320 Speaker 1: you a basic rundown of that, X ray diffraction allows 126 00:07:10,360 --> 00:07:14,360 Speaker 1: scientists to see the three dimensional structures of molecules by 127 00:07:14,400 --> 00:07:18,160 Speaker 1: blasting a crystal with X ray, so the rays bounce 128 00:07:18,400 --> 00:07:21,960 Speaker 1: off the atoms and diffract in different directions, and the 129 00:07:22,120 --> 00:07:26,200 Speaker 1: escaping X rays exposed photographic film to create this kind 130 00:07:26,200 --> 00:07:29,840 Speaker 1: of shadow of the molecule, and then scientists interpret the 131 00:07:29,880 --> 00:07:33,840 Speaker 1: photo to reveal the molecule shape and its measurements, and 132 00:07:34,040 --> 00:07:35,680 Speaker 1: you know, allows them to look at it on a 133 00:07:35,680 --> 00:07:39,560 Speaker 1: closer level. So Franklin used these techniques to discover a 134 00:07:39,600 --> 00:07:43,200 Speaker 1: lot of details about the structure of carbon, even as 135 00:07:43,240 --> 00:07:46,600 Speaker 1: it's heated and changes into other forms. So not just 136 00:07:46,680 --> 00:07:51,880 Speaker 1: carbon in a static state, but transforming. So Franklin was 137 00:07:51,920 --> 00:07:54,280 Speaker 1: doing good work in Paris, and by most accounts, the 138 00:07:54,320 --> 00:07:56,280 Speaker 1: three years or so that she was there were the 139 00:07:56,320 --> 00:07:59,160 Speaker 1: happiest ones of her life. According to that Physics Today 140 00:07:59,280 --> 00:08:01,960 Speaker 1: article by elk And, Franklin had friends in her Paris 141 00:08:02,040 --> 00:08:04,480 Speaker 1: lab and would hang out with them sometimes do things 142 00:08:04,480 --> 00:08:07,520 Speaker 1: like going hiking, and she became fluent in French and 143 00:08:07,600 --> 00:08:11,040 Speaker 1: skilled in French cooking, and just became really comfortable with 144 00:08:11,040 --> 00:08:14,360 Speaker 1: her life there. It provides a really stark contrast for 145 00:08:14,400 --> 00:08:16,080 Speaker 1: the next period of her life that we're going to 146 00:08:16,120 --> 00:08:19,360 Speaker 1: talk about, the one in which DNA takes center stage. 147 00:08:20,000 --> 00:08:21,720 Speaker 1: So now that I've set that up, I should go 148 00:08:21,800 --> 00:08:23,960 Speaker 1: right and telling you all about it, I guess. So. 149 00:08:24,040 --> 00:08:26,480 Speaker 1: Even though Franklin was happy in Paris, she got lured 150 00:08:26,480 --> 00:08:29,760 Speaker 1: away by the offer of a research fellowship from Sir 151 00:08:29,880 --> 00:08:33,840 Speaker 1: John T. Randall's Medical Research Council at King's College in London, 152 00:08:34,320 --> 00:08:36,760 Speaker 1: and also the chance to work on one of the 153 00:08:36,920 --> 00:08:40,120 Speaker 1: major scientific challenges of the moment, figuring out the structure 154 00:08:40,160 --> 00:08:43,839 Speaker 1: and function of DNA. And Randall especially wanted Franklin to 155 00:08:43,920 --> 00:08:46,560 Speaker 1: use the X ray diffraction techniques that she had mastered 156 00:08:46,600 --> 00:08:49,760 Speaker 1: to produce diffraction pictures of d n A. But when 157 00:08:49,840 --> 00:08:53,520 Speaker 1: Randall brought her in, Maurice Wilkins, a British biophysicist who 158 00:08:53,520 --> 00:08:56,479 Speaker 1: had been working in the same lab on the same project, 159 00:08:56,800 --> 00:08:59,439 Speaker 1: was not happy to have her around. They didn't work 160 00:08:59,480 --> 00:09:01,920 Speaker 1: well together there and ended up disliking each other the 161 00:09:02,080 --> 00:09:04,760 Speaker 1: entire time. They worked together pretty much right off the bat. Yeah, 162 00:09:04,760 --> 00:09:08,040 Speaker 1: and biographers have had a hard time figuring out why 163 00:09:08,120 --> 00:09:11,600 Speaker 1: exactly Wilkins and Franklin didn't get along. Somethink it's because 164 00:09:11,920 --> 00:09:14,840 Speaker 1: he happened to be a way traveling when Franklin got 165 00:09:14,960 --> 00:09:18,920 Speaker 1: hired and started her job, so when he returned, Wilkins 166 00:09:19,000 --> 00:09:22,760 Speaker 1: originally thought that she was working for him. Another point 167 00:09:22,760 --> 00:09:25,680 Speaker 1: of contention is that Franklin, of course had other ideas. 168 00:09:25,679 --> 00:09:27,960 Speaker 1: She knew she wasn't gonna be working for Wilkins. She 169 00:09:28,040 --> 00:09:31,800 Speaker 1: assumed that she'd be working independently. She thought she was 170 00:09:31,840 --> 00:09:35,520 Speaker 1: the boss exactly, so they both had conflicting ideas of 171 00:09:35,600 --> 00:09:38,720 Speaker 1: who is boss. And she also had more experience with 172 00:09:38,920 --> 00:09:41,240 Speaker 1: X ray diffraction techniques of course, I mean that was 173 00:09:41,280 --> 00:09:43,199 Speaker 1: why she was brought in in the first place, and 174 00:09:43,800 --> 00:09:46,280 Speaker 1: kind of forged ahead and took the lead with that, 175 00:09:46,360 --> 00:09:49,800 Speaker 1: so Wilkins might have felt that his project was being 176 00:09:50,040 --> 00:09:53,320 Speaker 1: taken away from him to some degree. Franklin was also 177 00:09:53,360 --> 00:09:57,000 Speaker 1: said to have a very serious, direct, and even argumentative 178 00:09:57,040 --> 00:09:59,600 Speaker 1: style when it came to her work, and Wilkins did 179 00:09:59,640 --> 00:10:02,000 Speaker 1: not take well to this. It said that when she 180 00:10:02,200 --> 00:10:04,640 Speaker 1: argued with him, he would really just shut down and 181 00:10:04,720 --> 00:10:07,040 Speaker 1: kind of give her the silent treatment. He just wouldn't respond, 182 00:10:07,280 --> 00:10:10,559 Speaker 1: So they didn't have a functioning relationship, not at all. 183 00:10:11,200 --> 00:10:14,200 Speaker 1: So this rivalry is probably one of the main reasons 184 00:10:14,240 --> 00:10:17,559 Speaker 1: that Franklin was so unhappy at King's College, and some 185 00:10:17,640 --> 00:10:21,800 Speaker 1: have theorized that her unhappiness was also related to sexism 186 00:10:21,840 --> 00:10:25,320 Speaker 1: towards female employees at king saying that women weren't even 187 00:10:25,360 --> 00:10:28,280 Speaker 1: allowed to eat lunch in the same dining rooms as men. 188 00:10:28,400 --> 00:10:32,120 Speaker 1: But there's been some new ideas on that theory. Yeah, 189 00:10:32,160 --> 00:10:34,080 Speaker 1: I mean, you see that luntioned a lot the whole 190 00:10:34,160 --> 00:10:37,680 Speaker 1: lunch thing, that they were excluded somehow from eating lunch 191 00:10:37,760 --> 00:10:41,760 Speaker 1: with their fellow scientists. But researchers such as Random Attics, 192 00:10:41,760 --> 00:10:44,840 Speaker 1: a Franklin biographer, have found in recent years that the 193 00:10:44,880 --> 00:10:48,160 Speaker 1: working environment at King's College was actually more welcoming to 194 00:10:48,240 --> 00:10:50,680 Speaker 1: female scientists than some have portrayed it to be. They 195 00:10:50,720 --> 00:10:52,520 Speaker 1: actually did get to eat lunch in the same room, 196 00:10:52,640 --> 00:10:56,559 Speaker 1: So Maddox thinks that Franklin's class and religion she was 197 00:10:56,640 --> 00:10:59,280 Speaker 1: Jewish and came from a wealthy family, may have actually 198 00:10:59,320 --> 00:11:01,800 Speaker 1: made her feel more out of place than anything else. 199 00:11:02,520 --> 00:11:05,280 Speaker 1: And though her demeanor in the lab was serious and 200 00:11:05,320 --> 00:11:09,840 Speaker 1: sometimes abrasive, many of her colleagues remember her as being witty, bright, interesting, 201 00:11:10,040 --> 00:11:13,440 Speaker 1: even fun in the lab, though of course Franklin was 202 00:11:13,600 --> 00:11:17,439 Speaker 1: all business and her rivalry with Wilkins didn't stop her 203 00:11:17,600 --> 00:11:21,440 Speaker 1: from investigating DNA fibers at all. Pretty soon after she 204 00:11:21,559 --> 00:11:24,640 Speaker 1: got to King's College, Franklin, working along with a student 205 00:11:24,679 --> 00:11:29,120 Speaker 1: named Raymond Gosling, managed to get some preliminary diffraction images 206 00:11:29,280 --> 00:11:32,880 Speaker 1: of a DNA molecule as it transformed from its dry 207 00:11:32,960 --> 00:11:36,280 Speaker 1: crystalline form, which she called the A form, to the 208 00:11:36,360 --> 00:11:40,559 Speaker 1: wet B form through an increase in relative humidity, and 209 00:11:41,040 --> 00:11:44,559 Speaker 1: from this From this observation, Franklin determined that the phosphate 210 00:11:44,600 --> 00:11:48,000 Speaker 1: groups that make up the backbone of DNA run along 211 00:11:48,080 --> 00:11:51,559 Speaker 1: the outside of the molecule, one of her first milestones 212 00:11:51,679 --> 00:11:55,080 Speaker 1: in determining the structure of DNA, because Previously people had 213 00:11:55,120 --> 00:11:57,400 Speaker 1: thought that they were on the inside, yes, and at 214 00:11:57,400 --> 00:11:59,280 Speaker 1: the bases were on the outside, So this was kind 215 00:11:59,280 --> 00:12:02,760 Speaker 1: of a major discovery for her. So in November of 216 00:12:02,840 --> 00:12:05,480 Speaker 1: nineteen fifty one, Franklin gave a talk in London about 217 00:12:05,480 --> 00:12:09,640 Speaker 1: her latest findings and American scientist James Watson was in attendance. 218 00:12:09,960 --> 00:12:13,240 Speaker 1: Watson and then graduate student Francis Crick had also been 219 00:12:13,280 --> 00:12:16,720 Speaker 1: working on figuring out DNA structure at another Medical Research 220 00:12:16,800 --> 00:12:20,520 Speaker 1: Council unit at Cavendish Laboratory and Cambridge, but they weren't 221 00:12:20,559 --> 00:12:23,800 Speaker 1: doing it by experimenting and collecting data. They were doing 222 00:12:23,800 --> 00:12:26,880 Speaker 1: it through deduction and model building. So when Watson heard 223 00:12:26,920 --> 00:12:30,400 Speaker 1: Franklin's talk, he didn't really take notes and he misinterpreted 224 00:12:30,400 --> 00:12:34,160 Speaker 1: her results, but still relayed what he'd heard incorrectly of course, 225 00:12:34,440 --> 00:12:36,839 Speaker 1: to Crick, and they used that info to slap together 226 00:12:36,880 --> 00:12:40,680 Speaker 1: a quick model with the sugar phosphate backbone on the inside. 227 00:12:41,400 --> 00:12:44,040 Speaker 1: So about a week after the talk, Franklin and Wilkins 228 00:12:44,120 --> 00:12:47,400 Speaker 1: visited Cambridge to check out Watson and Crick's model. As 229 00:12:47,400 --> 00:12:50,439 Speaker 1: soon as Franklin saw it, she immediately realized their mistake 230 00:12:50,520 --> 00:12:52,560 Speaker 1: and pointed out that the phosphate group should be on 231 00:12:52,559 --> 00:12:56,440 Speaker 1: the outside. And this experience probably just confirmed for Franklin 232 00:12:56,520 --> 00:13:00,760 Speaker 1: that careful and diligent experimentation was much more valuable than 233 00:13:00,840 --> 00:13:05,240 Speaker 1: making intuitively rash model building. So after this method, Watson 234 00:13:05,240 --> 00:13:09,079 Speaker 1: and Crick were actually told to refrain from DNA modeling 235 00:13:09,160 --> 00:13:12,880 Speaker 1: for a while, like just take take a focus on 236 00:13:12,960 --> 00:13:18,599 Speaker 1: proteins exactly. So Franklin continued to approach her DNA experiments 237 00:13:18,720 --> 00:13:23,000 Speaker 1: with that methodical, research based manner, and they helped her 238 00:13:23,040 --> 00:13:27,680 Speaker 1: determine DNA's density, its unit cell size, water content in 239 00:13:27,760 --> 00:13:32,480 Speaker 1: her phosphate distances, and other really precise kind of calculations. 240 00:13:32,559 --> 00:13:34,720 Speaker 1: And the one point she got a little bit tied 241 00:13:34,840 --> 00:13:38,199 Speaker 1: up on THEO was DNA's helical shape. So some scientists, 242 00:13:38,200 --> 00:13:42,439 Speaker 1: including her rival Wilkins, were convinced that DNA's shape was 243 00:13:42,480 --> 00:13:45,800 Speaker 1: helical before they had any proof of it. But as 244 00:13:45,880 --> 00:13:48,800 Speaker 1: we kind of mentioned, that wasn't Franklin's style at all. 245 00:13:48,880 --> 00:13:52,640 Speaker 1: She needed to prove it through experimentation, She needed to 246 00:13:52,679 --> 00:13:55,920 Speaker 1: observe it. Yeah, this was tough, though partly because she 247 00:13:56,120 --> 00:13:59,360 Speaker 1: was so methodical in her research. She started out by 248 00:13:59,480 --> 00:14:03,800 Speaker 1: focusing on the diffraction image of DNA's crystalline a form 249 00:14:03,840 --> 00:14:07,040 Speaker 1: in which it was much harder to discern that helical shape. 250 00:14:07,520 --> 00:14:09,840 Speaker 1: So at one point, after obtaining some data from the 251 00:14:09,880 --> 00:14:13,320 Speaker 1: A form which suggested that DNA was non helical, she 252 00:14:13,440 --> 00:14:17,240 Speaker 1: actually created this death of the Helix funeral invitation in 253 00:14:17,320 --> 00:14:21,080 Speaker 1: July ninetift two, and some kind of see this as 254 00:14:21,160 --> 00:14:24,280 Speaker 1: evidence that Franklin was on the wrong track and figuring 255 00:14:24,320 --> 00:14:28,480 Speaker 1: out DNA structure. Others, including Elkin in her Physics Today article, 256 00:14:28,600 --> 00:14:31,960 Speaker 1: note that it was a joke mainly directed at Wilkins. 257 00:14:31,960 --> 00:14:34,880 Speaker 1: And we actually, I think, yeah, we we have a 258 00:14:34,920 --> 00:14:39,760 Speaker 1: copy of this funeral invitation. It's it's quite interesting. It says, 259 00:14:39,800 --> 00:14:42,320 Speaker 1: written by hand, written by hand. It says, it is 260 00:14:42,360 --> 00:14:44,680 Speaker 1: with great regret that we have to announce the death 261 00:14:44,760 --> 00:14:49,600 Speaker 1: on Friday, eighteenth July nineteen fifty two of DNA helix parentheses. 262 00:14:49,800 --> 00:14:53,920 Speaker 1: Crystalline death followed a protracted illness which an intensive course 263 00:14:53,920 --> 00:14:57,640 Speaker 1: of injections has failed to relieve. A memorial service will 264 00:14:57,640 --> 00:15:00,960 Speaker 1: be held next Monday or Tuesday. It is hoped that 265 00:15:01,200 --> 00:15:04,600 Speaker 1: Dr M H. F. Wilkins will speak in memory of 266 00:15:04,680 --> 00:15:07,000 Speaker 1: the late helix. And then it signed with her name. 267 00:15:07,360 --> 00:15:09,880 Speaker 1: I mean, I think this certainly proves that she had 268 00:15:09,920 --> 00:15:14,600 Speaker 1: a sense of humor, yes, for sure. So Franklin's personal notebooks, 269 00:15:14,640 --> 00:15:18,720 Speaker 1: as well as information provided by Raymond Gosling, indicated that 270 00:15:18,800 --> 00:15:22,120 Speaker 1: she believed the B form to be heliical. But before 271 00:15:22,240 --> 00:15:25,880 Speaker 1: she could get all of her conclusions together, something truly 272 00:15:26,120 --> 00:15:30,720 Speaker 1: unexpected happened. Wilkins and Watson had kept in touch and 273 00:15:30,800 --> 00:15:33,720 Speaker 1: actually became pretty close after that meeting where they viewed 274 00:15:33,720 --> 00:15:37,560 Speaker 1: Watson and Cricks incorrect model, and in January of nineteen 275 00:15:37,600 --> 00:15:41,160 Speaker 1: fifty three, Watson came to King's College to visit with Wilkins, 276 00:15:41,240 --> 00:15:45,240 Speaker 1: and Wilkins showed him the now famous diffraction photo of 277 00:15:45,280 --> 00:15:48,240 Speaker 1: the B form of DNA that Franklin had taken in 278 00:15:48,360 --> 00:15:51,960 Speaker 1: May of nineteen fifty two, and that photo, which was 279 00:15:52,160 --> 00:15:55,520 Speaker 1: known as photo fifty one, was revolutionary because it was 280 00:15:55,600 --> 00:15:58,840 Speaker 1: the best photo of its kind at the time. And 281 00:15:59,240 --> 00:16:02,560 Speaker 1: Franklin took a photo looking down on the DNA molecule, 282 00:16:02,720 --> 00:16:06,520 Speaker 1: and what appeared was this very distinct ex pattern, which 283 00:16:06,560 --> 00:16:10,640 Speaker 1: was of course clear evidence that the molecule was helical. 284 00:16:11,440 --> 00:16:13,720 Speaker 1: So Franklin had apparently put the photo in a drawer 285 00:16:13,760 --> 00:16:15,640 Speaker 1: while she focused on the A form, and while it 286 00:16:15,680 --> 00:16:18,120 Speaker 1: was in that drawer, Wilkins was able to access it 287 00:16:18,480 --> 00:16:20,880 Speaker 1: some sources even suggest that he had been making copies 288 00:16:20,920 --> 00:16:22,680 Speaker 1: of all of her research to keep her from getting 289 00:16:22,720 --> 00:16:25,280 Speaker 1: ahead of him in a way, and when he showed 290 00:16:25,280 --> 00:16:28,200 Speaker 1: Watson Photo fifty one, though Watson and Krick were the 291 00:16:28,240 --> 00:16:32,120 Speaker 1: ones who instantly pulled ahead and the double helix. Watson 292 00:16:32,200 --> 00:16:35,520 Speaker 1: describes his reaction to the photo. He says, quote the 293 00:16:35,560 --> 00:16:37,760 Speaker 1: instant I saw the picture of my mouth fell open 294 00:16:37,800 --> 00:16:40,720 Speaker 1: and my pulse began to race. The pattern was unbelievably 295 00:16:40,760 --> 00:16:44,120 Speaker 1: simpler than those obtained previously, and Maurice told me he 296 00:16:44,160 --> 00:16:47,200 Speaker 1: was now quite convinced that she meaning Franklin, was correct, 297 00:16:47,720 --> 00:16:50,520 Speaker 1: and Watson immediately rushed back to Cambridge to tell Krick 298 00:16:50,600 --> 00:16:53,560 Speaker 1: what he'd seen. And meanwhile, Chrick had obtained a copy 299 00:16:53,600 --> 00:16:57,160 Speaker 1: of a nineteen fifty two Medical Research Council report which 300 00:16:57,200 --> 00:17:00,440 Speaker 1: contained a section including some of Franklin's data. So with 301 00:17:00,560 --> 00:17:02,920 Speaker 1: these two sources of information they were able to start 302 00:17:02,960 --> 00:17:06,199 Speaker 1: creating a correct model within about a week's time. And 303 00:17:06,240 --> 00:17:09,879 Speaker 1: then in April of nineteen fifty three, they published one 304 00:17:09,920 --> 00:17:13,000 Speaker 1: of the best known scientific papers of the century, called 305 00:17:13,600 --> 00:17:18,760 Speaker 1: a Structure for deoxy ribos nucleic Acid, in the journal Nature, 306 00:17:18,920 --> 00:17:22,520 Speaker 1: and in it they described their double helix DNA molecular 307 00:17:22,600 --> 00:17:26,159 Speaker 1: model with its complementary double strands forming the sides of 308 00:17:26,200 --> 00:17:30,840 Speaker 1: a twisting ladder and bassis forming the runs of that ladder, 309 00:17:31,000 --> 00:17:34,919 Speaker 1: and Franklin and Gosling revised a draft of their own 310 00:17:35,160 --> 00:17:38,399 Speaker 1: to appear along with Watson and Cricks, but partly because 311 00:17:38,440 --> 00:17:41,200 Speaker 1: of the placement it received in the journal. It seemed 312 00:17:41,680 --> 00:17:44,800 Speaker 1: to just support Watson and Crick's findings, even though her 313 00:17:44,840 --> 00:17:48,320 Speaker 1: research was a huge, if not the main reason why 314 00:17:48,440 --> 00:17:52,080 Speaker 1: their paper existed in the first place. Franklin only received 315 00:17:52,160 --> 00:17:55,000 Speaker 1: one line of acknowledgment in that nineteen fifty three Watson 316 00:17:55,000 --> 00:17:58,200 Speaker 1: and Crick paper. In his Nobel Prize acceptance speech in 317 00:17:58,320 --> 00:18:02,320 Speaker 1: nineteen sixty two, Wilkins only mentioned her after thanking thirteen 318 00:18:02,359 --> 00:18:05,600 Speaker 1: other colleagues by name. Watson and Krick didn't mention her 319 00:18:05,640 --> 00:18:08,520 Speaker 1: at all. So this is where the controversy begins, and 320 00:18:08,560 --> 00:18:11,840 Speaker 1: a lot of people wonder whether Franklin would have reached 321 00:18:11,840 --> 00:18:15,800 Speaker 1: the same conclusions as Watson encrypt did on her own eventually, 322 00:18:15,920 --> 00:18:18,080 Speaker 1: and a lot of people think that yes, she would have. 323 00:18:18,200 --> 00:18:21,840 Speaker 1: For one thing, unpublished drafts of her paper and information 324 00:18:22,040 --> 00:18:24,919 Speaker 1: in her note suggests that she was close to getting 325 00:18:24,920 --> 00:18:27,840 Speaker 1: the same results, and Krick even said in nineteen seventy 326 00:18:27,840 --> 00:18:31,640 Speaker 1: four that she was only two steps away from the solution. 327 00:18:32,359 --> 00:18:35,920 Speaker 1: In an excerpt from his memoir Avoid Boring People that 328 00:18:36,000 --> 00:18:40,119 Speaker 1: was published in Technology Review a few years ago, Watson said, quote, 329 00:18:40,400 --> 00:18:43,440 Speaker 1: Rosalind Franklin would have seen the double helix first, had 330 00:18:43,480 --> 00:18:45,879 Speaker 1: she seen fit to enter the model building race and 331 00:18:45,920 --> 00:18:49,480 Speaker 1: been better able to interact with other scientists. He also 332 00:18:49,520 --> 00:18:53,320 Speaker 1: told Scientific American quote, We're very famous because DNA is 333 00:18:53,440 --> 00:18:56,639 Speaker 1: very famous. If Rosalind had talked to Francis starting in 334 00:18:56,800 --> 00:19:00,240 Speaker 1: nineteen fifty one, shared her data with him, she would 335 00:19:00,240 --> 00:19:02,600 Speaker 1: have solved that structure, and then she would have been 336 00:19:02,600 --> 00:19:05,880 Speaker 1: the famous one. They did give her credit here and there, though, 337 00:19:05,880 --> 00:19:08,359 Speaker 1: of course there was Watson's book that we mentioned the 338 00:19:08,359 --> 00:19:11,720 Speaker 1: double helix, which reveals everything. But according to a two 339 00:19:11,800 --> 00:19:16,720 Speaker 1: thousand three article in Wilson Quarterly, as soon as nineteen four, 340 00:19:16,880 --> 00:19:20,760 Speaker 1: Crick had stated quote without Franklin's data, the formulation of 341 00:19:20,800 --> 00:19:25,120 Speaker 1: our structure would have been most unlikely, if not impossible. 342 00:19:25,800 --> 00:19:28,800 Speaker 1: Some take this as evidence that Franklin must have known 343 00:19:28,840 --> 00:19:31,639 Speaker 1: about the fact that Watson saw photo fifty one, but 344 00:19:31,720 --> 00:19:34,760 Speaker 1: others think that knowing her personality and how feisty she 345 00:19:34,800 --> 00:19:36,840 Speaker 1: could be. If she had known that they had seen 346 00:19:36,880 --> 00:19:40,359 Speaker 1: it without her permission, she would have been very angry. Ultimately, 347 00:19:40,480 --> 00:19:43,520 Speaker 1: Franklin's biographer Matic says there's no real evidence that she 348 00:19:43,600 --> 00:19:46,360 Speaker 1: knew what research of hers, Watson and Crick had obtained, 349 00:19:46,400 --> 00:19:49,159 Speaker 1: so that parts still kind of a mystery. What we 350 00:19:49,400 --> 00:19:52,480 Speaker 1: really know, though, is that Franklin didn't seem too troubled 351 00:19:52,520 --> 00:19:55,480 Speaker 1: about losing the race to discover the structure of DNA, 352 00:19:55,640 --> 00:19:59,359 Speaker 1: probably because she didn't consider herself in that race in 353 00:19:59,359 --> 00:20:02,880 Speaker 1: the first For her, it had all been about discovering 354 00:20:02,880 --> 00:20:06,200 Speaker 1: the truth. So Franklin was of course eager to get 355 00:20:06,240 --> 00:20:09,640 Speaker 1: out of King's College, considering how unhappy she was there, 356 00:20:09,680 --> 00:20:11,960 Speaker 1: and she did that. But the spring of eighteen fifty three, 357 00:20:12,000 --> 00:20:15,040 Speaker 1: around the same time that the Nature article was published, 358 00:20:15,359 --> 00:20:18,680 Speaker 1: she ended up taking a position working in the crystallography 359 00:20:18,800 --> 00:20:22,960 Speaker 1: laboratory at Birkbeck College in London, and it's there that 360 00:20:23,000 --> 00:20:26,240 Speaker 1: she began to work primarily on investigating the structure of 361 00:20:26,320 --> 00:20:31,080 Speaker 1: the tobacco mosaic virus. She published seventeen papers while she 362 00:20:31,160 --> 00:20:34,640 Speaker 1: was there, including four in Nature, and she was much 363 00:20:34,680 --> 00:20:36,800 Speaker 1: happier professionally. I mean, I think the fact that she 364 00:20:36,880 --> 00:20:41,760 Speaker 1: published seventeen papers. Shows this wasn't a woman to dwell 365 00:20:41,840 --> 00:20:44,359 Speaker 1: on not getting credit for something that happened in the past. 366 00:20:44,400 --> 00:20:47,400 Speaker 1: She was looking forward, definitely. And incidentally, we should mention 367 00:20:47,440 --> 00:20:50,160 Speaker 1: that when she left King's College, Randall basically told her, 368 00:20:50,680 --> 00:20:53,840 Speaker 1: you cannot work on DNA anymore. So it's not like 369 00:20:54,600 --> 00:20:56,760 Speaker 1: she just gave it up. I mean, she might have 370 00:20:56,800 --> 00:20:59,480 Speaker 1: just given it up anyway, but she wasn't allowed to 371 00:20:59,520 --> 00:21:03,520 Speaker 1: work on Addicially, in ninety six, she was diagnosed with 372 00:21:03,600 --> 00:21:06,840 Speaker 1: ovarian cancer. There was cancer in her family history, but 373 00:21:06,920 --> 00:21:08,840 Speaker 1: it also probably had a lot to do with her 374 00:21:08,880 --> 00:21:11,560 Speaker 1: work with X rays, during which she didn't ever wear 375 00:21:11,600 --> 00:21:14,879 Speaker 1: a lead apron or anything to protect herself, and she 376 00:21:14,960 --> 00:21:17,720 Speaker 1: often had to enter the radiation being for extended periods 377 00:21:17,720 --> 00:21:20,960 Speaker 1: to position specimens. So she just didn't realize at the 378 00:21:21,000 --> 00:21:23,480 Speaker 1: time how harmful it would be. Then we've talked a 379 00:21:23,480 --> 00:21:26,120 Speaker 1: little bit about that before on the Radium Girls episode 380 00:21:26,160 --> 00:21:30,800 Speaker 1: exactly so ironically, during the last years of Franklin's life, though, 381 00:21:31,280 --> 00:21:34,919 Speaker 1: she became friends with Watson and Crick, even convalescing at 382 00:21:35,000 --> 00:21:38,520 Speaker 1: Crick's home once after one of her cancer treatments, and 383 00:21:38,720 --> 00:21:42,119 Speaker 1: according to that Wilson Quarterly article. Qrick once said that 384 00:21:42,160 --> 00:21:46,240 Speaker 1: they never discussed the subject of the race to find 385 00:21:46,359 --> 00:21:48,840 Speaker 1: DNA structure. I mean, I don't know if you're suspicious 386 00:21:48,840 --> 00:21:51,080 Speaker 1: of I'm I'm a little suspicious of that. I mean, 387 00:21:51,119 --> 00:21:54,400 Speaker 1: I can imagine why it would be a taboo topic 388 00:21:54,560 --> 00:21:57,280 Speaker 1: between these people. You don't really want to bring it up, 389 00:21:57,280 --> 00:22:00,480 Speaker 1: perhaps especially if you're trying to be friends. But fact Lee, 390 00:22:00,840 --> 00:22:04,199 Speaker 1: But I mean, I do I do wonder what what 391 00:22:04,320 --> 00:22:06,719 Speaker 1: they really talked about, and if she wanted to know 392 00:22:06,760 --> 00:22:08,879 Speaker 1: how they got the information or anything like them. And 393 00:22:08,920 --> 00:22:11,600 Speaker 1: I guess we'll never know. Franklin died at the age 394 00:22:11,600 --> 00:22:14,760 Speaker 1: of thirty seven on April sixteenth, nineteen fifty eight, and 395 00:22:14,800 --> 00:22:17,240 Speaker 1: there have been at least a couple of biographies written 396 00:22:17,240 --> 00:22:19,119 Speaker 1: about her, and a documentary done on her that was 397 00:22:19,160 --> 00:22:22,320 Speaker 1: aired on PBS called The Secret of Photo fifty one. 398 00:22:22,760 --> 00:22:25,280 Speaker 1: And there are also a couple of institutions that have 399 00:22:25,480 --> 00:22:29,280 Speaker 1: named buildings after her, including King's College and Birkbeck College, 400 00:22:29,640 --> 00:22:34,119 Speaker 1: And interestingly enough, King's is called the Franklin Wilkins Building. 401 00:22:34,200 --> 00:22:38,560 Speaker 1: So she's kind of paired up with her, yes, So 402 00:22:39,119 --> 00:22:40,480 Speaker 1: I don't know. I think a good thing to point 403 00:22:40,520 --> 00:22:43,960 Speaker 1: out here is that by by talking about Franklin. We're 404 00:22:43,960 --> 00:22:47,760 Speaker 1: not trying to diminish any of the other's accomplishments. Obviously, 405 00:22:47,800 --> 00:22:50,679 Speaker 1: we think Watson and crit contributed a lot to this, 406 00:22:50,880 --> 00:22:54,480 Speaker 1: and without their modeling, no how they wouldn't have come 407 00:22:54,560 --> 00:22:57,000 Speaker 1: up with DNA structure, and who knows what would have happened. 408 00:22:57,040 --> 00:22:58,960 Speaker 1: I mean, everyone here deserves a little bit of credit. 409 00:22:59,000 --> 00:23:01,040 Speaker 1: But I think that kind of the point is that 410 00:23:01,080 --> 00:23:04,760 Speaker 1: there's enough recognition to go around. Well, in DNA is 411 00:23:04,800 --> 00:23:09,320 Speaker 1: such a huge discovery, such a huge accomplishment, there is 412 00:23:09,440 --> 00:23:13,959 Speaker 1: plenty of room for for four people. Yes, and um 413 00:23:14,040 --> 00:23:19,359 Speaker 1: Watson did kind of relent on his earlier feelings about Franklin. 414 00:23:19,520 --> 00:23:23,520 Speaker 1: Later in his epilogue to his book, he did say, quote, 415 00:23:23,560 --> 00:23:27,080 Speaker 1: since my initial impressions of her, both scientific and personal, 416 00:23:27,160 --> 00:23:29,280 Speaker 1: as recorded in the early pages of this book, and 417 00:23:29,280 --> 00:23:32,240 Speaker 1: of course we're referring to the double helix, we're often wrong. 418 00:23:32,440 --> 00:23:35,800 Speaker 1: I want to say something here about her achievements. And 419 00:23:35,840 --> 00:23:39,000 Speaker 1: then he says that he and Kirk both came to 420 00:23:39,080 --> 00:23:43,400 Speaker 1: appreciate her personal honesty and generosity, realizing years too late 421 00:23:43,440 --> 00:23:46,560 Speaker 1: the struggles that the intelligent woman faces to be accepted 422 00:23:46,560 --> 00:23:49,760 Speaker 1: by a scientific world which often regards women as near 423 00:23:49,840 --> 00:23:52,720 Speaker 1: diversions from serious thinking, so I don't think we could 424 00:23:52,720 --> 00:23:55,159 Speaker 1: put it any better than that. Not enough do we 425 00:23:55,200 --> 00:24:01,720 Speaker 1: have some listener mail. We do, so this message is 426 00:24:01,800 --> 00:24:05,040 Speaker 1: from Maggie and she wrote, Dear Sara Deblina. First of all, 427 00:24:05,119 --> 00:24:07,360 Speaker 1: let me tell you how much I love your podcast. 428 00:24:07,400 --> 00:24:10,480 Speaker 1: Since my husband left for Iraq earlier this year, you 429 00:24:10,520 --> 00:24:12,880 Speaker 1: have helped fill a quiet house with lots of fun, 430 00:24:13,040 --> 00:24:16,320 Speaker 1: interesting stories. So thanks for doing your part. From military family, 431 00:24:16,920 --> 00:24:19,359 Speaker 1: or at least this military family member, so that was 432 00:24:19,400 --> 00:24:22,080 Speaker 1: a really nice thing to say. Thank you, Maddie. Um, 433 00:24:22,119 --> 00:24:24,720 Speaker 1: she says, thankfully, come home next month, and since this 434 00:24:24,840 --> 00:24:28,879 Speaker 1: email came in November, should be home by now. Um. 435 00:24:28,920 --> 00:24:32,960 Speaker 1: She also wrote that she wanted to suggest some military 436 00:24:33,000 --> 00:24:36,359 Speaker 1: spouses as potential topics, and she said we are pretty 437 00:24:36,400 --> 00:24:39,720 Speaker 1: interesting bunch, if I do say so myself. Lady Custer 438 00:24:39,840 --> 00:24:43,200 Speaker 1: in particular prided herself on being quote the only officer's 439 00:24:43,240 --> 00:24:46,400 Speaker 1: wife who always followed the regiment and wrote a lot 440 00:24:46,440 --> 00:24:50,679 Speaker 1: about her experiences, including a book called Boots and Saddles. 441 00:24:51,040 --> 00:24:53,440 Speaker 1: I would love to hear what other military spouses from 442 00:24:53,480 --> 00:24:56,160 Speaker 1: different eras and parts of the world you come up with, 443 00:24:56,320 --> 00:25:00,520 Speaker 1: so thank you for that suggestion. Maggie, have we talked 444 00:25:00,520 --> 00:25:03,840 Speaker 1: about any military wives in the Civil War series yet? 445 00:25:04,480 --> 00:25:07,800 Speaker 1: I don't think we have. Um, I'm trying to remember 446 00:25:07,840 --> 00:25:10,600 Speaker 1: if any of the nurses were military wives, and many 447 00:25:10,640 --> 00:25:12,840 Speaker 1: of them were unmarried, so I don't think that's the case. 448 00:25:12,880 --> 00:25:15,000 Speaker 1: So it's definitely a topic that we could look into 449 00:25:15,040 --> 00:25:18,879 Speaker 1: some more. Yeah, so thank you for suggesting that one, Maggie, 450 00:25:19,000 --> 00:25:22,120 Speaker 1: And I hope you guys like this sort of scientific 451 00:25:22,200 --> 00:25:24,920 Speaker 1: kick we've been on lately. Yeah, we tend to get 452 00:25:24,920 --> 00:25:30,400 Speaker 1: obsessed with subjects for a little while. By medicine, I mean, 453 00:25:30,440 --> 00:25:32,800 Speaker 1: maybe it is the Civil War medicine ones that have 454 00:25:32,880 --> 00:25:36,040 Speaker 1: gotten us kind of off on a science tantary areas 455 00:25:36,080 --> 00:25:39,879 Speaker 1: of science, and I think the Halloween type episodes on 456 00:25:39,960 --> 00:25:42,560 Speaker 1: alchemy and so forth also kind of inspired me in 457 00:25:42,600 --> 00:25:45,040 Speaker 1: that direction very much. And just for those of you 458 00:25:45,080 --> 00:25:47,600 Speaker 1: who don't know, we do have a whole science themed 459 00:25:47,680 --> 00:25:50,080 Speaker 1: podcast here at How Stuff Works called Stuff to Blow 460 00:25:50,119 --> 00:25:53,560 Speaker 1: Your Mind, which they go into some more like nitty 461 00:25:53,560 --> 00:25:57,080 Speaker 1: gritty science stuff, So that might, um, that might be 462 00:25:57,119 --> 00:26:00,000 Speaker 1: great for for those of you who love these science 463 00:26:00,119 --> 00:26:03,280 Speaker 1: gamed episodes. That's very true. And if any of you 464 00:26:03,320 --> 00:26:08,040 Speaker 1: guys have any more episode suggestions, whether science or otherwise. 465 00:26:08,160 --> 00:26:10,680 Speaker 1: Please write us where History podcast at how staff works 466 00:26:10,720 --> 00:26:13,879 Speaker 1: dot com or we're on Facebook and we're also on 467 00:26:13,920 --> 00:26:17,240 Speaker 1: Twitter at Myston History. And I'm sure we have articles 468 00:26:17,320 --> 00:26:20,919 Speaker 1: on on DNA and we have how DNA works. In fact, 469 00:26:20,960 --> 00:26:22,720 Speaker 1: if you want to find out a little bit more 470 00:26:22,760 --> 00:26:25,520 Speaker 1: of the technical side of what we talked about, that's 471 00:26:25,520 --> 00:26:28,960 Speaker 1: the homepage editor in Dublina coming through. It knows exactly 472 00:26:28,960 --> 00:26:31,119 Speaker 1: what articles are on the right, so you can go 473 00:26:31,240 --> 00:26:33,600 Speaker 1: check that one out. It's called how DNA Works and 474 00:26:33,680 --> 00:26:36,480 Speaker 1: you can find it by searching on our homepage at 475 00:26:36,600 --> 00:26:43,240 Speaker 1: www dot how stuff works dot com. Be sure to 476 00:26:43,320 --> 00:26:46,120 Speaker 1: check out our new video podcast, Stuff from the Future. 477 00:26:46,440 --> 00:26:48,720 Speaker 1: Join how stup work staff as we explore the most 478 00:26:48,760 --> 00:26:53,359 Speaker 1: promising and perplexing possibilities of tomorrow. The house Stuff Works 479 00:26:53,359 --> 00:26:56,600 Speaker 1: iPhone app has a rise. Download it today on iTunes 480 00:27:01,320 --> 00:27:01,359 Speaker 1: in