WEBVTT - Selects: Maggots: Good For Healing Wounds, Turns Out

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<v Speaker 1>Hello there, it's Josh and for this week's S Y

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<v Speaker 1>s K Selex, I've chosen maggots colon good for healing wounds.

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<v Speaker 1>Turns out, uh, and that is absolutely true. Um, I

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<v Speaker 1>really listened to all of our select episodes, and I

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<v Speaker 1>listen to this one, and I'm clearly excited in the episode.

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<v Speaker 1>But I was just as excited listening to it all

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<v Speaker 1>these years later, but five years after we released it. Um,

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<v Speaker 1>So I hope it excites you. It is groty, but

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<v Speaker 1>it's also pretty awesome. So enjoy slash prepared to be

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<v Speaker 1>grossed out. Welcome to Stuff you should know, a production

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<v Speaker 1>of My Heart Radios How Stuff Works. Hey, and welcome

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<v Speaker 1>to the podcast. I'm Josh Clark. There's Charles W. Chuck Bryant,

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<v Speaker 1>and uh, no one, no one else is in here

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<v Speaker 1>with us yet again, because we've graduated to the point

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<v Speaker 1>where we don't even need a producer. We need so

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<v Speaker 1>body who presses record and leaves Yep, that's it, because

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<v Speaker 1>we're pros Yep, not p R O s E. P

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<v Speaker 1>R Oh that's right, we're not. But we are prosaic, yes,

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<v Speaker 1>but definitely not p r O apostrophees. Very few things

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<v Speaker 1>drive me crazier than that. And I know it's stupid

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<v Speaker 1>and pedantic, but to see, like somebody take out a

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<v Speaker 1>huge billboard or something and so a word has an

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<v Speaker 1>apostrophe that shouldn't prose. People say, like, leave it to

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<v Speaker 1>the pros and they'll put an apostrophe. Yes, and it's

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<v Speaker 1>it's that graphic designer should be, you know, doctor half

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<v Speaker 1>a day's paying maybe eight bucks. Something we want to

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<v Speaker 1>issue and you probably would get this from the title

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<v Speaker 1>of the episode, but we want to issue a meal warning.

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<v Speaker 1>Oh good thinking, because we've gotten complaints in the past

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<v Speaker 1>when people are eating and get sick listening to some

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<v Speaker 1>of these, Yeah, this would do it possibly for some people.

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<v Speaker 1>I was fine, I ate a runny yolk egg sandwich

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<v Speaker 1>while I white writer. Yeah right, it didn't bother me,

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<v Speaker 1>but I could totally see how it could be any people.

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<v Speaker 1>I also want to say, um, if it comes up,

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<v Speaker 1>do not go Google image search wound sloth. Well, I

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<v Speaker 1>just put do not Google image search maggot therapy at all. Okay, sure,

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<v Speaker 1>but definitely stay away from wound sloth s l o

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<v Speaker 1>U g H. Yeah, wow, it definitely don't look at

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<v Speaker 1>wound slough while you're eating. Yeah, okay, so that's all

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<v Speaker 1>out of the way. Yes, I predict we're going to

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<v Speaker 1>be kind of excited about this one. I'm feeling a

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<v Speaker 1>little pumped about it. Well, we did cover in uh

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<v Speaker 1>tin bizarre medical treatments uh leech therapy, which is still

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<v Speaker 1>being used, and I'm surprised this wasn't in that article.

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<v Speaker 1>To be honest, I am as well. But this gets

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<v Speaker 1>its own special deal, and well it should actually because

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<v Speaker 1>it's a pretty amazing thing. Um, we're talking about maggot therapy. Also,

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<v Speaker 1>by the way, yes it is they were awesome so

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<v Speaker 1>or they really or is it a band name? Well,

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<v Speaker 1>it's a band name to end all band names. There

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<v Speaker 1>probably was a band name that, So there's it's called

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<v Speaker 1>maggot therapy, maggot debridement therapy, larval therapy, or bio. There's

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<v Speaker 1>another one called I think like bio biodebridement or therapeutic

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<v Speaker 1>wound misses. Yeah, and that's basically all the all of them,

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<v Speaker 1>no matter what you call it, no matter how you

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<v Speaker 1>church it up. It is the application of live maggots

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<v Speaker 1>fly larva to purposefully to an open wound in order

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<v Speaker 1>to help that wound heal. Faster and better and cleaner

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<v Speaker 1>and everything. Dat punk said, Oh yeah, you know, should

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<v Speaker 1>we talk about some of the history of this stuff.

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<v Speaker 1>Let's just say that one more time. Okay. Maggot debridement

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<v Speaker 1>therapy is taking live maggots and put getting them in

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<v Speaker 1>an open wound on a human being or an animal.

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<v Speaker 1>It's used in veterinary medicine as well, wrapping it up

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<v Speaker 1>tight and letting them just eat the dead and dying

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<v Speaker 1>flesh of that wound while you get your foot tickled. Okay,

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<v Speaker 1>I would be so skiped out by this. I just

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<v Speaker 1>wanted to make sure that everybody knows exactly what we're

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<v Speaker 1>talking about, right, and goodbye to everyone everyone who fainted. Okay, Yeah,

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<v Speaker 1>let's talk about the history, chuck, because this is um.

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<v Speaker 1>This is in use today, but it's actually pretty old. Yeah,

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<v Speaker 1>I mean it's it's some say it's an even an

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<v Speaker 1>ancient tradition, like in places like Burma in Central America

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<v Speaker 1>with the Mayan's um. They were smart enough to know

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<v Speaker 1>that maggots do a pretty good job of consuming human flesh. Uh,

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<v Speaker 1>and it can be used for good in that regard. Yeah,

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<v Speaker 1>at some point I guess healers noticed like yef. People

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<v Speaker 1>who had maggots in their wounds tended to have wounds

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<v Speaker 1>heal U. And actually, as far as the Western literature goes,

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<v Speaker 1>that's exactly how um maggot therapy first finds its way,

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<v Speaker 1>first crawls into the medical literature is from a French

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<v Speaker 1>surgeon named Ambro Ambras Poare. Yeah, but how would you say,

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<v Speaker 1>I don't know, I don't speak French Ambras even though

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<v Speaker 1>it doesn't have the little what is that an accent? Yeah,

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<v Speaker 1>it's just the e. But he was a sixteenth century

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<v Speaker 1>surgeon and he noticed that, um, that people didn't necessarily

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<v Speaker 1>fall over dead if there was a maggot in the wound. Yeah.

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<v Speaker 1>He was the first doctor to actually come out and say,

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<v Speaker 1>you know, I had this patient with a big skull wound,

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<v Speaker 1>and unbeknownst to me, there were maggots in there. I

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<v Speaker 1>saw them crawling out one day. And even though they

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<v Speaker 1>had a lot of bone. Um, the guy was great.

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<v Speaker 1>He healed like he lost a hand sized slab of

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<v Speaker 1>skull and he lived. And I think it might have

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<v Speaker 1>something to do with the maggots. And he presumably were

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<v Speaker 1>a helmet for the us of his life. Probably he

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<v Speaker 1>had a probably big soft skull there, I guess so. Uh.

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<v Speaker 1>That was followed in uh with the mid seventeen hundreds

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<v Speaker 1>by another Frenchy baron, Dominique Jean Laoie uh, and he said,

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<v Speaker 1>you know what, on this Egyptian expedition, Uh, these blue

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<v Speaker 1>fly maggots are actually doing the right thing and helping

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<v Speaker 1>us out. So it's almost like these doctors just noticed

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<v Speaker 1>this exactly and it meant enough to him that they

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<v Speaker 1>were like, I should probably write this down. This is

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<v Speaker 1>going to be my great contribution to medical history of

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<v Speaker 1>the history of science, right. Um. So it wasn't until

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<v Speaker 1>the uh, I guess, the Civil War that a doctor

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<v Speaker 1>actually said I'm going to purposefully put maggots in a

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<v Speaker 1>wound and see what happens. And that doctor was John

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<v Speaker 1>Forney Zacharias. He probably didn't tell his patient that. I

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<v Speaker 1>think probably that he was just like, just bite down

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<v Speaker 1>on this brooms and the other way. Do you want

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<v Speaker 1>to lose your foot or do you want to try

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<v Speaker 1>something really weird? Well, supposedly in studies of people, modern

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<v Speaker 1>patients who are offered this therapy say yes to it. Well, yeah,

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<v Speaker 1>because I think that's what it comes down to. You

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<v Speaker 1>it's a last resort. Basically, it's not the first thing

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<v Speaker 1>they offer, not necessarily. Um So, Anyway, doctor Zacharias um

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<v Speaker 1>Hey had a great quote. He said, during my service

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<v Speaker 1>in the hospital at Danville, Virginia, I first used maggots

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<v Speaker 1>to remove the decayed tissue in Hospital Gang Green, and

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<v Speaker 1>with my eminent satisfaction, in a single day, they would

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<v Speaker 1>clean a wound much better than any agents we had

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<v Speaker 1>at our command. I used them afterwards at various places.

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<v Speaker 1>I am sure I saved many lives by their use,

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<v Speaker 1>escaped sept to semia, and had rapid recoveries period. End quote.

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<v Speaker 1>Pretty great. Yeah. So he was a huge believer and

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<v Speaker 1>not just a passive observer like people who came before him.

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<v Speaker 1>He said, Yeah, I put maggots on wounds and it helps,

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<v Speaker 1>That's right. And uh, people experimented with it for a

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<v Speaker 1>little while until um a guy named Louis Pasteur and

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<v Speaker 1>Robert Coke came along, uh microbiologists and germ theorists that

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<v Speaker 1>basically said, you know, this is this is disgusting. We

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<v Speaker 1>might want to not do this. Yeah, because they're dirty.

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<v Speaker 1>Yeah yeah, and it's true. Maggots naturally in the wild

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<v Speaker 1>carry lots of pathogens with them that UM can infect

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<v Speaker 1>us in other ways, can make a wound worse, can

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<v Speaker 1>actually kill you. So this the idea behind germ theory

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<v Speaker 1>as far as maggots goes. Right. But UM, it seems

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<v Speaker 1>like there's this long history of necessity and disgusted with

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<v Speaker 1>maggot therapy that kind of wayne ebbs and flows right,

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<v Speaker 1>and necessity rears its head on the battlefield. It did

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<v Speaker 1>in the Civil War, and it also did in World

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<v Speaker 1>War One. There was a surgeon UM named William S.

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<v Speaker 1>Bayer and he was working on the front lines in France,

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<v Speaker 1>and he used maggots on stomach wounds and open fractures,

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<v Speaker 1>and he found, to his great satisfaction, just like Dr

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<v Speaker 1>Zacharias and the other before him, that this stuff actually worked. Yeah,

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<v Speaker 1>And he actually said, you know what, I have some

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<v Speaker 1>further advancements. UM, maybe we should put a bandage over

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<v Speaker 1>this thing so it doesn't completely discussed the patient. Uh,

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<v Speaker 1>And let me UM put bandages around the wound, so

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<v Speaker 1>they don't start creeping onto the healthy flesh and doing

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<v Speaker 1>damage or just itching you or creeping you out further

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<v Speaker 1>right exactly, UM, which are still in use today. These techniques.

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<v Speaker 1>He also pioneered another huge technique, and this is after

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<v Speaker 1>the war was over. Ten years later, when he was

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<v Speaker 1>back at Johns Hopkins UM. He he pioneered another really

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<v Speaker 1>important technique, and that was using sterilized um maggots. Like

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<v Speaker 1>germ free maggots. They were raised as eggs in a

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<v Speaker 1>sterile environment and so when they were introduced to the wounds,

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<v Speaker 1>they weren't carrying these pathogens anymore. And he found this

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<v Speaker 1>is the jackpot. Now you can use maggots from now on.

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<v Speaker 1>That's right. And there was a big boom in the

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<v Speaker 1>thirties up until the mid nineteen forties. Uh, three more

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<v Speaker 1>than three hundred American hospitals. Uh, we're using maggot treatment,

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<v Speaker 1>maggot therapy. And then in uh antiseptics came along, or

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<v Speaker 1>you know, new antiseptics and they said, you know what,

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<v Speaker 1>maybe there was another lull in the use of maggot theory. Right,

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<v Speaker 1>Necessity didn't didn't spur this stuff, and it was they

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<v Speaker 1>went back to just being gross again. There was a

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<v Speaker 1>guy um who by the eighties wrote what what this

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<v Speaker 1>one article calls the majority opinion. Fortunately, maggot therapy is

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<v Speaker 1>now relegated to a historical backwater of interest more for

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<v Speaker 1>its bizarre nature than its effect on the course of

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<v Speaker 1>medical science. A therapy the demise of which no one

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<v Speaker 1>is likely to mourn. That's just that kind of Western

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<v Speaker 1>medicine hubris, where like we can do anything except everything,

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<v Speaker 1>you know. Uh, that's right. And in the nineteen nineties, UM,

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<v Speaker 1>a dude named Ronald Sherman and Edward peck Or basically

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<v Speaker 1>champion the technique again and kind of brought it into

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<v Speaker 1>the modern age. Yeah, and still very much is. Um.

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<v Speaker 1>Ronald Sherman is one of the first, I think, to

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<v Speaker 1>receive a license to produce sterile maggots for use as

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<v Speaker 1>medical devices. Um. And there's another guy over in uh

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<v Speaker 1>the UK named John Church um who who brought the

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<v Speaker 1>maggot their maggot therapy into the four So it was

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<v Speaker 1>an ancient thing, it was. It's found to be disgusting,

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<v Speaker 1>it's found to be useful, it's found to be disgusting,

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<v Speaker 1>it's found ways you can make it better. It's found

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<v Speaker 1>to be disgusting. And then now that this idea of

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<v Speaker 1>complimentary medicine is is kind of regaining some traction again. UM,

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<v Speaker 1>I think it's here to stay. Though I think so too,

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<v Speaker 1>unless someone comes along in ten years is you know

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<v Speaker 1>what it's disgusting, Well, you know the chuck. I mean

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<v Speaker 1>probably what we're seeing is the next thing that will

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<v Speaker 1>happen is there will be some huge leaps, some huge

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<v Speaker 1>development in science, and science will get its tackles up

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<v Speaker 1>again and great about itself and we don't need any

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<v Speaker 1>of that stupid nastiness. And then we'll find that Nope,

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<v Speaker 1>you still can't beat good old fashioned maggots. And that's

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<v Speaker 1>that should be the title of this thing. You can't

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<v Speaker 1>beat good old fashioned maggots for healing a wound that

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<v Speaker 1>won't heal otherwise. It's a great title. So you want

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<v Speaker 1>to take a break, Uh, yeah, let's do it, and

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<v Speaker 1>we'll go um treat our own wounds and we'll be

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<v Speaker 1>back shortly. All right, Let's talk about diabetes for a second. Yeah,

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<v Speaker 1>more than twenty three million Americans are affected with diabetes.

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<v Speaker 1>And one thing that can happen, uh is nerve damage,

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<v Speaker 1>especially in the extremities the hands and feet and the

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<v Speaker 1>toes and the and the fingers. Your blood vessels become

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<v Speaker 1>hard and they don't circulate the blood like you need.

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<v Speaker 1>That can lead to open sores called ulcers, which can

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<v Speaker 1>become infections, which can spread to nearby bone, which can

0:13:31.080 --> 0:13:33.960
<v Speaker 1>lead to amputation. Yeah, and all of all this is

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<v Speaker 1>just from a prolonged exposure to high levels of blood

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<v Speaker 1>sugar and they're not sure how it can do it.

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<v Speaker 1>But yeah, the blood, the blood vessels not helping pump

0:13:42.280 --> 0:13:45.160
<v Speaker 1>blood very well get nutrients or your tissue can die.

0:13:45.400 --> 0:13:49.880
<v Speaker 1>But also that neuropathy that dead and nerves cell um

0:13:49.960 --> 0:13:52.920
<v Speaker 1>that actually makes it hard for you to notice. If

0:13:52.960 --> 0:13:55.560
<v Speaker 1>you have like a really bad ulcer on the bottom

0:13:55.600 --> 0:13:57.679
<v Speaker 1>of your foot, you can't feel it. Yeah, and so

0:13:57.720 --> 0:13:59.800
<v Speaker 1>you don't get treatment early enough, so it can get

0:13:59.800 --> 0:14:02.160
<v Speaker 1>an infection, can get out of hand, and when it

0:14:02.200 --> 0:14:07.520
<v Speaker 1>spreads to bone that's called osteo myelitis. That's problematic because

0:14:07.559 --> 0:14:10.480
<v Speaker 1>that very quickly will lead to an amputation. And there's

0:14:10.520 --> 0:14:14.240
<v Speaker 1>some pretty shocking stats here from this article that Tom wrote,

0:14:14.760 --> 0:14:19.360
<v Speaker 1>Um about this sheave jam Yeah nice, it's yeah for sure, Um,

0:14:19.560 --> 0:14:24.440
<v Speaker 1>But about amputations from diabetes, Yes, seventy thousand to foot

0:14:24.440 --> 0:14:27.520
<v Speaker 1>and leg amputations each year in the United States alone,

0:14:28.520 --> 0:14:31.280
<v Speaker 1>and uh they say around the world, they estimate every

0:14:31.320 --> 0:14:35.840
<v Speaker 1>thirty seconds someone gets a limb cut off because of diabetes. Yeah,

0:14:36.080 --> 0:14:38.800
<v Speaker 1>that's sad. Yeah, it really is, and we should. We

0:14:38.800 --> 0:14:41.760
<v Speaker 1>will do one on diabetes for sure. Oh yeah, I'm

0:14:41.840 --> 0:14:47.720
<v Speaker 1>surprised we haven't already. Um. But the so amputation is

0:14:48.680 --> 0:14:52.640
<v Speaker 1>used to halt the progress of an infection, and that's

0:14:52.720 --> 0:14:55.840
<v Speaker 1>usually the last resort. But what's what Tom points out

0:14:55.880 --> 0:14:59.160
<v Speaker 1>is that there are plenty of doctors around the world

0:14:59.240 --> 0:15:03.160
<v Speaker 1>I imagine that aren't aware that you can use maggots

0:15:03.480 --> 0:15:06.400
<v Speaker 1>or have ever done it before. And if you are

0:15:06.440 --> 0:15:10.320
<v Speaker 1>facing an amputation from say like a wound, a persistent wound,

0:15:10.320 --> 0:15:13.440
<v Speaker 1>a chronic wound that won't heal, Um, you may want

0:15:13.480 --> 0:15:15.960
<v Speaker 1>to suggest maggots to your doctor. You may have to

0:15:15.960 --> 0:15:20.040
<v Speaker 1>actually take this the the initiative on this one and say,

0:15:20.600 --> 0:15:23.560
<v Speaker 1>let's make sure the amputation is the absolute last resort.

0:15:23.640 --> 0:15:25.480
<v Speaker 1>Let's see if we can put one more resort in

0:15:25.520 --> 0:15:28.560
<v Speaker 1>there before then I'm willing to let maggots crawl inside

0:15:28.600 --> 0:15:32.360
<v Speaker 1>my body in this wounds open wound if you're willing

0:15:32.400 --> 0:15:36.280
<v Speaker 1>to apply them. And they uh, like most doctors love

0:15:36.360 --> 0:15:40.600
<v Speaker 1>hearing when patients suggest treatments. Oh they do. They love feedback.

0:15:40.920 --> 0:15:44.960
<v Speaker 1>They love to be guided in their diagnoses and prognoses. Yeah,

0:15:45.040 --> 0:15:47.360
<v Speaker 1>I love it. That's a tough jam. I get it.

0:15:47.640 --> 0:15:50.000
<v Speaker 1>Doctors are frustrated a lot of these days with self

0:15:50.040 --> 0:15:53.520
<v Speaker 1>diagnosis and online doctoring. But you should also be your

0:15:53.520 --> 0:15:56.200
<v Speaker 1>own advocate. We can't be in that before. Yeah it's

0:15:56.280 --> 0:15:58.600
<v Speaker 1>your leg. Yeah you want to keep your leg. You

0:15:58.680 --> 0:16:00.720
<v Speaker 1>tell that doctor to go get some maggots. You're going

0:16:00.720 --> 0:16:03.160
<v Speaker 1>to replace them with the doctor who will. I can

0:16:03.200 --> 0:16:05.160
<v Speaker 1>find a guy, Yeah, I can get a guy by

0:16:05.160 --> 0:16:07.840
<v Speaker 1>noon that'll put maggots on that wound. And actually there's

0:16:07.880 --> 0:16:10.720
<v Speaker 1>a there's a group I think Ronald Sherman, the guy

0:16:10.800 --> 0:16:14.080
<v Speaker 1>we mentioned earlier who's like the the US champion of

0:16:14.160 --> 0:16:18.080
<v Speaker 1>maggot therapy. UM. It's there's this group called the B

0:16:18.320 --> 0:16:22.080
<v Speaker 1>Turf Foundation B T e Er Foundation, UM, and they

0:16:22.120 --> 0:16:26.440
<v Speaker 1>have all sorts of resources for people in that very situation,

0:16:26.920 --> 0:16:30.600
<v Speaker 1>like how to talk to your doctor, UM that if

0:16:30.680 --> 0:16:33.120
<v Speaker 1>your insurance won't cover it, let them know, because they

0:16:33.160 --> 0:16:37.920
<v Speaker 1>say insurance actually most insurance covers maggot therapy, but most

0:16:37.960 --> 0:16:41.160
<v Speaker 1>insurance claims people are not aware of that, so you

0:16:41.200 --> 0:16:43.680
<v Speaker 1>may get denied at first. And here's how to talk

0:16:43.720 --> 0:16:46.840
<v Speaker 1>to your insurance company. That's it really is. That beats

0:16:46.880 --> 0:16:48.800
<v Speaker 1>going to your doctor and saying well, you know what

0:16:48.920 --> 0:16:51.840
<v Speaker 1>Josh and Chuck said. He you're not gonna like hearing this,

0:16:52.520 --> 0:16:55.120
<v Speaker 1>right because you think you know it all doctor, please

0:16:55.120 --> 0:16:58.280
<v Speaker 1>take a sleep and be put maggots on my feet, right.

0:16:58.320 --> 0:17:00.240
<v Speaker 1>And and that's the other thing too, I mean, like

0:17:01.000 --> 0:17:04.360
<v Speaker 1>we wouldn't be suggesting this and the Better Foundation probably

0:17:04.359 --> 0:17:07.440
<v Speaker 1>wouldn't be such advocates for it if it didn't work

0:17:07.880 --> 0:17:13.320
<v Speaker 1>so amazingly. Well, it's study after study, and we'll talk

0:17:13.359 --> 0:17:15.960
<v Speaker 1>about the details of it, but there's so many studies

0:17:16.040 --> 0:17:20.400
<v Speaker 1>out there. Um Again. Sherman, who agreed, is an advocate,

0:17:20.440 --> 0:17:23.080
<v Speaker 1>but in a pure reviewed journal published a survey of

0:17:23.160 --> 0:17:26.240
<v Speaker 1>studies that he could find on maggot therapy, and it's

0:17:26.400 --> 0:17:30.160
<v Speaker 1>very clear that it works really really well, and not

0:17:30.240 --> 0:17:34.199
<v Speaker 1>only necessarily um as a means of last resort, but

0:17:34.240 --> 0:17:38.280
<v Speaker 1>even just compared to the standard of care using like

0:17:38.359 --> 0:17:40.560
<v Speaker 1>hydrogell or other things that you might use to treat

0:17:40.560 --> 0:17:44.000
<v Speaker 1>a chronic wound. Maggots destroy it, They leave it in

0:17:44.040 --> 0:17:46.600
<v Speaker 1>the dust. Yeah. And if it doesn't work, it's not

0:17:46.640 --> 0:17:50.399
<v Speaker 1>gonna hurt anything. Yeah. Yeah, it just puts off how

0:17:50.480 --> 0:17:53.360
<v Speaker 1>much longer before they amputate your foot? Pretty much? Yeah.

0:17:54.080 --> 0:17:56.320
<v Speaker 1>Uh so what will happen is they will Well, let's

0:17:56.359 --> 0:17:59.680
<v Speaker 1>get into this a little bit. Um, there are four

0:17:59.760 --> 0:18:01.480
<v Speaker 1>differ friend, and you where did you find this? Was

0:18:01.520 --> 0:18:05.159
<v Speaker 1>this a a research paper? Yeah? This is by Ronald

0:18:05.240 --> 0:18:09.800
<v Speaker 1>Sherman Mechanisms of maggot induced wound healing colin What do

0:18:09.880 --> 0:18:11.919
<v Speaker 1>we know and where do we go from here? It

0:18:12.000 --> 0:18:15.200
<v Speaker 1>was in the journal Evidence Based, Complimentary and Alternative Medicine

0:18:15.240 --> 0:18:17.600
<v Speaker 1>in two thousand and fourteen, that's right, And he describes

0:18:18.040 --> 0:18:26.440
<v Speaker 1>four different phases of basically healing a wound um homeostasis, inflammation, ploriferate. Man,

0:18:26.480 --> 0:18:31.880
<v Speaker 1>I'm so bad at that one. Oh yeah, keep it coming, proliferation,

0:18:32.040 --> 0:18:36.679
<v Speaker 1>nice going, and uh remodeling and maturing. And what happens

0:18:36.720 --> 0:18:39.440
<v Speaker 1>is the cells get to work, they recruit other cells,

0:18:39.480 --> 0:18:42.879
<v Speaker 1>they alter their activities and basically say, let's get to

0:18:42.920 --> 0:18:47.240
<v Speaker 1>work cleaning and uh, well on all four of these

0:18:47.280 --> 0:18:51.359
<v Speaker 1>stages to help heal the wound. Yeah, and at any

0:18:51.400 --> 0:18:55.720
<v Speaker 1>any one of those stages, Um that the next process

0:18:55.800 --> 0:19:00.000
<v Speaker 1>can stall out. Um. Normally it stalls out at inflamation

0:19:00.000 --> 0:19:02.879
<v Speaker 1>ation because the infection gets out of hand in the

0:19:02.960 --> 0:19:07.399
<v Speaker 1>body can't fight off the infection faster than it's laying

0:19:07.440 --> 0:19:11.200
<v Speaker 1>The extracellular matrix for the new cells to be rebuilt,

0:19:11.200 --> 0:19:14.760
<v Speaker 1>the new tissue to recro um. And that's that's it's

0:19:14.800 --> 0:19:17.800
<v Speaker 1>a common thing that leads to chronic wounds. Yes, they

0:19:17.880 --> 0:19:20.360
<v Speaker 1>just won't heal. And that's where maggots are really really

0:19:20.440 --> 0:19:24.680
<v Speaker 1>useful to basically interrupt that stall and get the car

0:19:24.760 --> 0:19:26.879
<v Speaker 1>moving again in the right direction. It's exactly right, they

0:19:26.920 --> 0:19:31.440
<v Speaker 1>kick started. Uh. So debridemant is removing dead tissue, and

0:19:31.480 --> 0:19:36.439
<v Speaker 1>that is really where maggots excel um. They said, Uh,

0:19:36.560 --> 0:19:39.800
<v Speaker 1>in here, each maggot can chew, Well they don't exactly chew,

0:19:39.800 --> 0:19:43.119
<v Speaker 1>which we'll get to. Uh. They remove twenty five milligrams

0:19:43.200 --> 0:19:47.760
<v Speaker 1>of necrotic material dead flesh, uh, in just twenty four hours. Yeah,

0:19:47.920 --> 0:19:51.280
<v Speaker 1>that's pretty good. Yeah, and uh, there's there's actually three

0:19:51.320 --> 0:19:54.760
<v Speaker 1>ways that maggots clean a wound. But debridement, which is

0:19:54.800 --> 0:19:58.200
<v Speaker 1>getting in there and like just cleaning out, removing physically

0:19:58.240 --> 0:20:02.760
<v Speaker 1>removing um that dead material. That's like the key that

0:20:02.800 --> 0:20:05.640
<v Speaker 1>seems to be the key. And then there's also um

0:20:05.680 --> 0:20:10.439
<v Speaker 1>anti microbial activity like actually killing the bacteria that's killing

0:20:10.440 --> 0:20:13.040
<v Speaker 1>the flesh, leaving it cleaner than when they came in, Yeah,

0:20:13.119 --> 0:20:18.880
<v Speaker 1>which is amazing. And then even more astounding stimulating new growth,

0:20:19.600 --> 0:20:22.600
<v Speaker 1>like the act the presence of maggots in your wound

0:20:23.280 --> 0:20:27.840
<v Speaker 1>stimulates new tissue growth around your skin. It's the most

0:20:28.160 --> 0:20:33.040
<v Speaker 1>they're just like wonder creatures who knew. One of the

0:20:33.040 --> 0:20:37.000
<v Speaker 1>ways that they remove this dead tissue is just by

0:20:37.040 --> 0:20:40.400
<v Speaker 1>the nature of what their body is like. And they

0:20:40.400 --> 0:20:44.399
<v Speaker 1>have these little prickly spines all over their body that

0:20:44.560 --> 0:20:48.359
<v Speaker 1>act as a surgeon's rasp rasper or file what It

0:20:48.440 --> 0:20:51.119
<v Speaker 1>Basically just the fact that they're moving around on the

0:20:51.160 --> 0:20:55.000
<v Speaker 1>wound is going to like file the stuff down and

0:20:55.119 --> 0:20:58.000
<v Speaker 1>scrape the wound, which helps loosens it up. It's like

0:20:58.040 --> 0:21:01.000
<v Speaker 1>a plow. It burrows through this dieing and dead tissue

0:21:01.600 --> 0:21:04.120
<v Speaker 1>and it just, yeah, it loosens up. That's part one

0:21:04.160 --> 0:21:07.240
<v Speaker 1>of derived Part one. There's another part of it, which

0:21:07.320 --> 0:21:11.480
<v Speaker 1>is the digestive enzymes that they excrete and secrete. It's

0:21:11.520 --> 0:21:15.639
<v Speaker 1>called alimentary secretions and excretions a s C. It's basically

0:21:15.680 --> 0:21:18.680
<v Speaker 1>they're digestive juices, right, and they puke these up as

0:21:18.680 --> 0:21:22.640
<v Speaker 1>they're moving around and they just they just puke them

0:21:22.680 --> 0:21:26.639
<v Speaker 1>everywhere and it dissolves this flesh. Yeah. I remember in

0:21:26.680 --> 0:21:29.239
<v Speaker 1>the Body Farms episode we we talked about this one

0:21:29.359 --> 0:21:32.760
<v Speaker 1>one of the old classics. And that's why I said earlier.

0:21:32.760 --> 0:21:35.720
<v Speaker 1>They don't bite or choose something. They just liquefy it

0:21:36.119 --> 0:21:38.320
<v Speaker 1>and then suck it in. And this this A s

0:21:38.359 --> 0:21:42.200
<v Speaker 1>C stuff is so greedy that it liquefies more dead

0:21:42.240 --> 0:21:46.119
<v Speaker 1>flesh than the maggots can even consume, and they consume

0:21:46.240 --> 0:21:49.240
<v Speaker 1>quite a bit, Like you said, twenty five milligrams. That's

0:21:49.240 --> 0:21:52.040
<v Speaker 1>a lot for a little tiny maggot in one day.

0:21:52.119 --> 0:21:54.479
<v Speaker 1>But even more than that, they're liquefying even more of

0:21:54.480 --> 0:21:57.800
<v Speaker 1>this dead tissue. So that part of the process of

0:21:58.240 --> 0:22:03.640
<v Speaker 1>maggot debridemant therapy is draining out this liquefied necrotic tissue

0:22:04.280 --> 0:22:08.840
<v Speaker 1>that's become liquefied from the alimentary or the the A

0:22:09.040 --> 0:22:11.920
<v Speaker 1>s C stuff. The digest events ons, right, So you've

0:22:11.960 --> 0:22:15.840
<v Speaker 1>got them burrowing around, you've got them puking into your wound,

0:22:16.800 --> 0:22:21.760
<v Speaker 1>liquefying the dead tissue, leaving pretty much entirely the living

0:22:21.800 --> 0:22:25.359
<v Speaker 1>tissue alone, and then you just kind of drain out

0:22:25.720 --> 0:22:29.040
<v Speaker 1>the stuff that's that's in there. And the reason um

0:22:29.080 --> 0:22:33.000
<v Speaker 1>that maggots are considered by the FDA a medical device

0:22:33.480 --> 0:22:37.119
<v Speaker 1>rather than a drug is because the whole process of

0:22:37.200 --> 0:22:40.720
<v Speaker 1>dibrid mint isn't just a reaction to the chemicals. It

0:22:40.840 --> 0:22:43.640
<v Speaker 1>is part of that mechanical movement of the maggots through

0:22:43.640 --> 0:22:46.600
<v Speaker 1>the wound. So it's a drug, it's a device. I

0:22:46.640 --> 0:22:51.280
<v Speaker 1>mean it's a device. Look at them, yea, and those

0:22:51.359 --> 0:22:56.640
<v Speaker 1>that the secretions are so potent. They have basically DNA

0:22:57.040 --> 0:23:01.880
<v Speaker 1>destroying qualities, Like they not only just break down tissue,

0:23:02.000 --> 0:23:05.560
<v Speaker 1>they destroy the d N A. It's pretty amazing stuff

0:23:06.040 --> 0:23:09.119
<v Speaker 1>it is. Should we take another break? Yeah, I'm a

0:23:09.119 --> 0:23:11.639
<v Speaker 1>little excited. We probably should. Alright, I'm gonna go to

0:23:11.680 --> 0:23:15.960
<v Speaker 1>the vomitorium. Are you grossed out slightly? I am not

0:23:16.119 --> 0:23:18.520
<v Speaker 1>in the least. What does that say about me? I

0:23:20.320 --> 0:23:23.159
<v Speaker 1>don't know. You have a stronger stomach, but I don't necessarily,

0:23:23.200 --> 0:23:25.399
<v Speaker 1>I'm I'm just excited. All right, we'll go watch me

0:23:25.520 --> 0:23:48.239
<v Speaker 1>vomited at least. Okay, that will gross me out? All right?

0:23:48.320 --> 0:23:50.760
<v Speaker 1>Well that was disgusting, it was It made me throw

0:23:50.840 --> 0:23:57.639
<v Speaker 1>up in turn. Uh So here's a couple of questions. Um,

0:23:57.800 --> 0:24:01.400
<v Speaker 1>does it hurt? Maybe a little bit at first. Yeah,

0:24:01.600 --> 0:24:04.080
<v Speaker 1>I don't get the feeling that it's extremely painful. It

0:24:04.160 --> 0:24:07.560
<v Speaker 1>probably depends on the wound. Um, but it can the

0:24:07.600 --> 0:24:10.439
<v Speaker 1>first few treatments can apparently be a little bit painful, right,

0:24:10.440 --> 0:24:13.360
<v Speaker 1>And there's there's actually two mechanisms for the pain. One

0:24:13.600 --> 0:24:17.760
<v Speaker 1>is that an open wound, right, and you have maggots

0:24:17.760 --> 0:24:20.080
<v Speaker 1>crawling over the exposed nerves in your open wound. That's

0:24:20.119 --> 0:24:22.359
<v Speaker 1>not gonna feel good, No, it won't. Uh. And then

0:24:22.440 --> 0:24:25.240
<v Speaker 1>number two, pressure in the wound can increase as the

0:24:25.280 --> 0:24:29.200
<v Speaker 1>maggots get bigger from eating so much dead flesh. That's right.

0:24:29.359 --> 0:24:33.360
<v Speaker 1>So yes, the the the cure to that is pain killers, which, frankly,

0:24:33.359 --> 0:24:36.040
<v Speaker 1>if you have an open wound with exposed nerves, you

0:24:36.040 --> 0:24:38.440
<v Speaker 1>should probably be on those anyway. Sure you will be,

0:24:38.840 --> 0:24:41.560
<v Speaker 1>so it probably won't hurt because there'll be some sort

0:24:41.600 --> 0:24:45.439
<v Speaker 1>of pain management going on, but you will still feel

0:24:45.800 --> 0:24:49.720
<v Speaker 1>most likely unless the doctor completely numbs the area maggots

0:24:49.720 --> 0:24:52.359
<v Speaker 1>crawling around inside the wound. See, that's what That's the

0:24:52.359 --> 0:24:56.359
<v Speaker 1>part that gets me is actually thinking about undergoing this

0:24:56.440 --> 0:24:59.760
<v Speaker 1>therapy myself is what gets me, not like seeing it

0:24:59.880 --> 0:25:02.400
<v Speaker 1>or reading about it, but thinking about having an open

0:25:02.400 --> 0:25:04.760
<v Speaker 1>wound on the bottom of my foot and having maggots

0:25:04.760 --> 0:25:07.040
<v Speaker 1>creeping around in there. See. The thing is I think

0:25:07.320 --> 0:25:10.560
<v Speaker 1>anybody would feel that way. There's very few included myself.

0:25:10.600 --> 0:25:12.600
<v Speaker 1>I'm not grossed out by this, but I wouldn't want

0:25:12.600 --> 0:25:15.879
<v Speaker 1>maggots talking wound. But I think if your backs against

0:25:15.960 --> 0:25:19.920
<v Speaker 1>the wall, uh that, or you lose your foot, I try.

0:25:20.040 --> 0:25:23.719
<v Speaker 1>I would definitely try. I think as people would apparently

0:25:23.840 --> 0:25:27.359
<v Speaker 1>man and I would demand some high quality drugs. And

0:25:27.359 --> 0:25:32.600
<v Speaker 1>they also have um what is it called amnesiotics to

0:25:32.680 --> 0:25:35.480
<v Speaker 1>make you forget about so you can't form memories while

0:25:35.520 --> 0:25:37.560
<v Speaker 1>it's happening. So maybe that would be a nice thing

0:25:37.600 --> 0:25:40.159
<v Speaker 1>to do too. So the other question is can you

0:25:40.240 --> 0:25:42.760
<v Speaker 1>just use any kind of maggot and the answer is no.

0:25:43.640 --> 0:25:46.119
<v Speaker 1>What they found is the most useful is the larva

0:25:46.240 --> 0:25:49.640
<v Speaker 1>of the green blow fly. And like we said earlier,

0:25:49.680 --> 0:25:52.240
<v Speaker 1>these things are now grown just sort of like the

0:25:52.280 --> 0:25:56.600
<v Speaker 1>medical leeches there shipped and sterile containers, uh as if

0:25:56.600 --> 0:25:59.040
<v Speaker 1>it were medicine, even though it's a device. And the

0:25:59.400 --> 0:26:03.200
<v Speaker 1>B T. E. R. Foundation they go into a lot

0:26:03.240 --> 0:26:06.439
<v Speaker 1>about this like could anybody do this? And they say, well, no,

0:26:06.640 --> 0:26:10.320
<v Speaker 1>because you need a prescription. It's an FDA control yourself.

0:26:10.800 --> 0:26:15.639
<v Speaker 1>But they say anybody who can read can basically follow

0:26:15.680 --> 0:26:19.280
<v Speaker 1>the instructions on the package. I wouldn't, I mean, I

0:26:19.320 --> 0:26:22.560
<v Speaker 1>wouldn't advise that as your non doctor. Sure, I'm not

0:26:22.600 --> 0:26:24.680
<v Speaker 1>saying that either, but I mean this may be your

0:26:24.720 --> 0:26:28.280
<v Speaker 1>doctor's first time to their Their point was is it's

0:26:28.320 --> 0:26:31.800
<v Speaker 1>not it's not difficult. Just follow the instructions on the packet.

0:26:31.960 --> 0:26:34.600
<v Speaker 1>If you win. Your doctor though, he got the maggots

0:26:34.600 --> 0:26:36.520
<v Speaker 1>out and he put on his bifocals and was like,

0:26:36.600 --> 0:26:38.479
<v Speaker 1>all right, let's see how to do this right or

0:26:38.520 --> 0:26:41.800
<v Speaker 1>like he tears the package open. They go everywhere you have,

0:26:41.880 --> 0:26:46.280
<v Speaker 1>like Jerry Lewis as a doctor. Uh oh. But although

0:26:46.320 --> 0:26:48.600
<v Speaker 1>they do say, um, you can't just load it up

0:26:48.640 --> 0:26:50.840
<v Speaker 1>with maggots. There should be no more than eight maggots

0:26:50.840 --> 0:26:54.000
<v Speaker 1>per square centimeter. Yeah, I saw five to eight. And

0:26:54.080 --> 0:26:58.399
<v Speaker 1>so when you have the maggots applied to your um wound,

0:26:59.040 --> 0:27:02.720
<v Speaker 1>they're going to make sure that the healthy area around

0:27:02.760 --> 0:27:04.760
<v Speaker 1>the wound is covered up so the maggots can't get

0:27:04.800 --> 0:27:07.120
<v Speaker 1>to it, which goes back to World War two. Yeah,

0:27:07.560 --> 0:27:10.040
<v Speaker 1>they're going to cover it, cover up the wound after

0:27:10.119 --> 0:27:12.800
<v Speaker 1>they apply the maggots five to eight per square centimeter,

0:27:12.920 --> 0:27:14.840
<v Speaker 1>like you say, and they're going to cover it up

0:27:14.880 --> 0:27:17.400
<v Speaker 1>so they can't wander off because maggots like to leave

0:27:17.480 --> 0:27:22.920
<v Speaker 1>before their work is done. Um TV, they're full pretty much, um,

0:27:23.080 --> 0:27:25.280
<v Speaker 1>but they can still eat more if you'll keep them

0:27:25.280 --> 0:27:28.480
<v Speaker 1>in there so they will cover up. They'll put the

0:27:28.520 --> 0:27:30.399
<v Speaker 1>maggots in five to eight cover it up with this

0:27:30.520 --> 0:27:33.840
<v Speaker 1>bandage and basically they will just sit there and eat

0:27:33.960 --> 0:27:38.520
<v Speaker 1>for between forty eight and seventy two hours, and then

0:27:38.840 --> 0:27:42.280
<v Speaker 1>the bandage will be removed. The maggots will then sadly

0:27:42.600 --> 0:27:47.640
<v Speaker 1>be incinerated or put into an autoclave or put into

0:27:47.720 --> 0:27:51.439
<v Speaker 1>a plasma gas of fire, or bronzed and hung on

0:27:51.480 --> 0:27:54.480
<v Speaker 1>your wall for real, like an ant farm. Yeah, because

0:27:54.480 --> 0:27:58.040
<v Speaker 1>it's like, thank you for this great contribution to saving

0:27:58.119 --> 0:28:02.280
<v Speaker 1>my foot, Now go be autoclave today. I would name

0:28:02.320 --> 0:28:06.439
<v Speaker 1>them and save them and preserve them. Um, you'd be

0:28:06.520 --> 0:28:09.480
<v Speaker 1>violating I'm sure all sorts of medical waste laws, but

0:28:09.920 --> 0:28:12.840
<v Speaker 1>who cares and so and then that's that's what's called

0:28:12.840 --> 0:28:17.120
<v Speaker 1>the treatment cycle. And most patients UH supposedly go between

0:28:17.200 --> 0:28:21.880
<v Speaker 1>two and four treatment cycles. And again, while this is happening,

0:28:22.200 --> 0:28:25.320
<v Speaker 1>what's going on is the maggots are debriding the dead flesh,

0:28:25.440 --> 0:28:29.720
<v Speaker 1>they're liquefying it, they're eating it, and they're also disinfecting

0:28:29.760 --> 0:28:33.320
<v Speaker 1>it and stimulating growth. Right, pretty amazing. So with the

0:28:33.400 --> 0:28:36.639
<v Speaker 1>with this, with the disinfecting, they figured that there was

0:28:37.040 --> 0:28:41.680
<v Speaker 1>some sort of gut flora that the maggots have that

0:28:41.880 --> 0:28:45.160
<v Speaker 1>prevents them from being infected by micropoil. That would make

0:28:45.160 --> 0:28:47.280
<v Speaker 1>sense because they're in that riting flesh as well and

0:28:47.280 --> 0:28:50.480
<v Speaker 1>they're thriving, right, So what gives Well, it turns out

0:28:50.520 --> 0:28:54.600
<v Speaker 1>that there are a couple of um types of I'm

0:28:54.600 --> 0:28:58.280
<v Speaker 1>not quite sure what what kind of um bacteria they are,

0:28:58.840 --> 0:29:03.160
<v Speaker 1>but they are. Oh that's not true. The proteus mirabilious

0:29:03.800 --> 0:29:06.520
<v Speaker 1>is a type of symbiotic microbe that you find in

0:29:06.560 --> 0:29:09.440
<v Speaker 1>the gut of a maggot, right, And this thing just

0:29:10.000 --> 0:29:14.680
<v Speaker 1>destroys microbial life. So it's killing the bacteria that's causing

0:29:14.680 --> 0:29:18.280
<v Speaker 1>this infection in your wound. But there's something that that maggots.

0:29:18.320 --> 0:29:20.360
<v Speaker 1>This is yet another thing. So think about it, Chuck,

0:29:20.440 --> 0:29:24.000
<v Speaker 1>Like you said, maggots, The very structure of a maggot

0:29:24.000 --> 0:29:29.680
<v Speaker 1>body dibrides the wound. That's amazing. This maggot anti microbial

0:29:29.760 --> 0:29:32.840
<v Speaker 1>stuff not only does it kill microbes, it destroys the

0:29:32.880 --> 0:29:36.480
<v Speaker 1>thing that naturally protects microbes, which is called biofilm. Yeah,

0:29:36.480 --> 0:29:39.560
<v Speaker 1>we've talked about biofilm a lot on this show, and um,

0:29:39.600 --> 0:29:44.200
<v Speaker 1>it's basically it's basically a film, like a literal film,

0:29:44.320 --> 0:29:47.720
<v Speaker 1>like a They call it a polymeric matrix. But the

0:29:47.760 --> 0:29:50.280
<v Speaker 1>easiest way to say in Layman's terment is it's a film, right,

0:29:50.280 --> 0:29:53.480
<v Speaker 1>It's like a protective coding. Yeah. And the little spiny bodies,

0:29:53.560 --> 0:29:55.160
<v Speaker 1>like one way they get rid of the thing is

0:29:55.240 --> 0:29:57.600
<v Speaker 1>by roughing it up, And that's exactly what the little

0:29:57.600 --> 0:30:00.440
<v Speaker 1>bodies do, right, And that's part of surgical I've meant

0:30:00.440 --> 0:30:03.600
<v Speaker 1>with like um, like going in there and scrubbing a

0:30:03.680 --> 0:30:07.840
<v Speaker 1>wound um with I don't know, steel wool or something

0:30:07.920 --> 0:30:10.720
<v Speaker 1>like that that will break up the biofilm. It's also

0:30:10.800 --> 0:30:15.479
<v Speaker 1>must be awfully painful, right. Maggots naturally can destroy not

0:30:15.560 --> 0:30:18.200
<v Speaker 1>just the bacteria but also the biofilm that protects it

0:30:18.240 --> 0:30:22.800
<v Speaker 1>to which makes them extremely handy with things like MERSA

0:30:22.880 --> 0:30:28.880
<v Speaker 1>and other antibiotic resistant um bacteria and all kinds of ulcers, right,

0:30:29.240 --> 0:30:32.040
<v Speaker 1>not like internal ulcers, but the open wound kind right,

0:30:32.080 --> 0:30:36.640
<v Speaker 1>exactly from diabetes, from bed sores um. And there's been

0:30:36.680 --> 0:30:38.600
<v Speaker 1>a lot of studies of people with bed sores that

0:30:38.680 --> 0:30:41.480
<v Speaker 1>have found that maggots help those kind of ulcers tremendously,

0:30:42.040 --> 0:30:44.600
<v Speaker 1>so Uh, let's talk about this one study or a

0:30:44.600 --> 0:30:48.000
<v Speaker 1>couple of studies. Actually, UM, there was one study of

0:30:48.040 --> 0:30:52.400
<v Speaker 1>spinal cord injury patients that had non healing ulcers, which

0:30:52.400 --> 0:30:55.120
<v Speaker 1>is the problem. And they monitored them over three to

0:30:55.200 --> 0:30:58.640
<v Speaker 1>four weeks UM, and they were getting regular wound care

0:30:58.640 --> 0:31:00.880
<v Speaker 1>at the same time, like sometimes it's used in conjunction

0:31:01.000 --> 0:31:05.680
<v Speaker 1>I think usually is used in conjunction with like standard care. UH.

0:31:05.720 --> 0:31:09.680
<v Speaker 1>And they found that uh, after three or four weeks

0:31:09.680 --> 0:31:12.800
<v Speaker 1>of maggot therapy, tissue quality and wound size were ressessed

0:31:12.840 --> 0:31:16.600
<v Speaker 1>weekly and they found that debridement was achieved in less

0:31:16.600 --> 0:31:19.560
<v Speaker 1>than fourteen days an average of ten days, and none

0:31:19.600 --> 0:31:22.400
<v Speaker 1>of the control group wounds were more than fifty dibrided

0:31:22.760 --> 0:31:26.720
<v Speaker 1>after a month. A month, not even half dibrided. None

0:31:26.720 --> 0:31:29.480
<v Speaker 1>of the wounds, not half the wounds were divided, None

0:31:29.480 --> 0:31:32.120
<v Speaker 1>of the wounds were even half dibrided after a month

0:31:32.200 --> 0:31:34.800
<v Speaker 1>chuck of the control group. Yes, amazing where they didn't

0:31:34.840 --> 0:31:40.600
<v Speaker 1>use the maggots. Yes, that's that's objectively amazing. It is.

0:31:40.640 --> 0:31:43.600
<v Speaker 1>And then they did a larger clinical trial and found uh,

0:31:43.840 --> 0:31:46.160
<v Speaker 1>this time they got two hundred and sixty three subjects,

0:31:46.200 --> 0:31:48.520
<v Speaker 1>which is pretty good for this kind of rare treatment

0:31:48.560 --> 0:31:52.560
<v Speaker 1>for uh. And they found that um, using the hydrogel

0:31:52.560 --> 0:31:56.800
<v Speaker 1>which you mentioned earlier, compression dressings, just the standard care,

0:31:58.040 --> 0:32:01.640
<v Speaker 1>that was the control. Yeah, that's obvious. The control. They

0:32:01.640 --> 0:32:05.080
<v Speaker 1>differed significantly between the three groups. Um, what was the

0:32:05.080 --> 0:32:07.640
<v Speaker 1>third group? The third group used bio bags, which are

0:32:07.680 --> 0:32:09.840
<v Speaker 1>like it's like a little pouch. You said it was

0:32:09.880 --> 0:32:13.240
<v Speaker 1>like a rav healthy Yeah, and it's filled with live maggots,

0:32:13.280 --> 0:32:15.720
<v Speaker 1>but it prevents them from burrowing. All it is is

0:32:15.840 --> 0:32:19.479
<v Speaker 1>using their chemical secretions. Yeah, I don't That to me

0:32:19.600 --> 0:32:21.920
<v Speaker 1>is just like why go halfway? Right? Exactly? Well, a

0:32:22.000 --> 0:32:24.160
<v Speaker 1>lot of people are like, I don't want a maggot

0:32:24.200 --> 0:32:27.120
<v Speaker 1>crawling in my wound, but a bag of them is

0:32:27.160 --> 0:32:30.800
<v Speaker 1>fine doing the shake shake near my wound. Right. So, um,

0:32:31.040 --> 0:32:33.320
<v Speaker 1>it actually has been shown to be not nearly as

0:32:33.360 --> 0:32:37.320
<v Speaker 1>effective as just letting what's called free range maggots burrow

0:32:37.400 --> 0:32:40.040
<v Speaker 1>through the wound. So they found the media time for

0:32:40.080 --> 0:32:43.760
<v Speaker 1>debryment was fourteen days with free range, twenty eight days

0:32:43.800 --> 0:32:47.840
<v Speaker 1>with the bagged ravioli, and seventy two days for the control.

0:32:48.080 --> 0:32:52.000
<v Speaker 1>Yeah that's pretty amazing. Yeah, Like, I I don't know,

0:32:52.040 --> 0:32:54.960
<v Speaker 1>I don't think it should be a last resort. You know,

0:32:55.320 --> 0:32:58.200
<v Speaker 1>I agree, and I think that increasingly it's becoming less

0:32:58.240 --> 0:33:00.400
<v Speaker 1>and less of the last resort because I mean, you

0:33:00.440 --> 0:33:03.520
<v Speaker 1>can compare it to the control, Like the standard of

0:33:03.560 --> 0:33:07.080
<v Speaker 1>care took seventy two days for the wound to be divided,

0:33:07.280 --> 0:33:10.719
<v Speaker 1>free range maggots fourteen days. That to me says that

0:33:10.800 --> 0:33:13.560
<v Speaker 1>free range maggots top the standard of care as it

0:33:13.640 --> 0:33:16.800
<v Speaker 1>stands right now. But like you say, there's a lot

0:33:16.840 --> 0:33:19.280
<v Speaker 1>of people who are saying this is just a last resort.

0:33:19.520 --> 0:33:21.560
<v Speaker 1>The next thing we're gonna do is amputate your foot.

0:33:21.560 --> 0:33:24.080
<v Speaker 1>But let's try this one last time. Or in the

0:33:24.120 --> 0:33:28.760
<v Speaker 1>case of persistent infections from like MERSA, where just antibiotics

0:33:28.920 --> 0:33:32.479
<v Speaker 1>just don't work, let's let's try maggots and see if

0:33:32.520 --> 0:33:34.680
<v Speaker 1>we can fix it. And maggots do work. There was

0:33:34.680 --> 0:33:38.280
<v Speaker 1>a study that found that of thirteen people treated who

0:33:38.320 --> 0:33:43.320
<v Speaker 1>had MERSA treated with maggots alone, twelve of the thirteen

0:33:43.680 --> 0:33:49.240
<v Speaker 1>had complete recovery and wound healing um from a mercer infection.

0:33:49.400 --> 0:33:51.760
<v Speaker 1>Mercu's nasty stuff too. Yeah, I think did we do

0:33:51.800 --> 0:33:55.600
<v Speaker 1>what I'm MERSA. I feel like we did. I know

0:33:55.640 --> 0:33:57.120
<v Speaker 1>we've talked about it. I don't know if it got

0:33:57.160 --> 0:33:59.440
<v Speaker 1>its own show though may have been in the should

0:33:59.440 --> 0:34:04.280
<v Speaker 1>we outlaw anti bacterial soap episode? Well, there's been a

0:34:04.280 --> 0:34:08.600
<v Speaker 1>lot of them, almost eight hundred. Uh you got anything else?

0:34:12.560 --> 0:34:18.120
<v Speaker 1>Surely I do, but I guess not. Um. Oh yeah,

0:34:18.160 --> 0:34:21.040
<v Speaker 1>Well there's one other thing we kept kind of teasing it.

0:34:21.040 --> 0:34:25.240
<v Speaker 1>It actually stimulates growth. A couple of studies have found

0:34:25.680 --> 0:34:31.480
<v Speaker 1>that the presence of maggots um produce more blood vessel

0:34:31.680 --> 0:34:37.239
<v Speaker 1>redevelopment and tissue redevelopment than maggots not being present. So

0:34:37.400 --> 0:34:41.560
<v Speaker 1>something about them actually stimulates tissue growth and blood vessel growth,

0:34:41.719 --> 0:34:45.560
<v Speaker 1>which promotes wound healing even more. Up with maggots. Up

0:34:45.600 --> 0:34:48.680
<v Speaker 1>with maggots, indeed, Man, I love them. I'm so psyched

0:34:48.680 --> 0:34:51.200
<v Speaker 1>about maggots right now. Well, it definitely changes the way

0:34:51.239 --> 0:34:52.800
<v Speaker 1>you think about them. Like, next time you see a

0:34:53.440 --> 0:34:58.160
<v Speaker 1>the dead squirrel that you've killed, they're clearly trying to

0:34:58.160 --> 0:34:59.680
<v Speaker 1>bring it back to life. Yeah, and you see the

0:34:59.680 --> 0:35:02.319
<v Speaker 1>maggot you can. You don't think that's disgusting. You just

0:35:02.360 --> 0:35:05.960
<v Speaker 1>think those are little things doing their thing, doing their thing.

0:35:06.120 --> 0:35:08.839
<v Speaker 1>Little things doing their thing. Now I'm going to autoclave them,

0:35:09.000 --> 0:35:11.400
<v Speaker 1>that's right. Uh. If you want to know more about

0:35:11.440 --> 0:35:14.320
<v Speaker 1>maggot therapy, you can type those words in the search

0:35:14.400 --> 0:35:17.160
<v Speaker 1>bar at how stuff forks dot com. And since I

0:35:17.200 --> 0:35:23.719
<v Speaker 1>said search parts time forward listener, I'm gonna call this

0:35:23.800 --> 0:35:28.359
<v Speaker 1>taken to task somewhat over a term. Guys, I want

0:35:28.360 --> 0:35:30.879
<v Speaker 1>to say you are my favorite podcast by far. I've

0:35:30.880 --> 0:35:33.960
<v Speaker 1>been listening since you were just a little five minute blurbs.

0:35:34.320 --> 0:35:37.120
<v Speaker 1>Oh man, you sure have grown up. I've never written

0:35:37.160 --> 0:35:39.080
<v Speaker 1>in before, but felt a head to comment on Josh's

0:35:39.080 --> 0:35:44.279
<v Speaker 1>statement that climate change was for global warming was settled science. No,

0:35:44.400 --> 0:35:46.360
<v Speaker 1>I'm not disputing the data that shows an increase in

0:35:46.360 --> 0:35:50.600
<v Speaker 1>global temperatures. While you can certainly argue it's accuracy, especially

0:35:50.640 --> 0:35:52.920
<v Speaker 1>for older data, it's still just data. It's not science.

0:35:53.560 --> 0:35:56.120
<v Speaker 1>The part that gets me upset about the term settled sciences.

0:35:56.320 --> 0:36:00.640
<v Speaker 1>By definition, science is never settled, and that's an all caps.

0:36:01.400 --> 0:36:03.040
<v Speaker 1>I think we talked a lot about this is the

0:36:03.120 --> 0:36:05.680
<v Speaker 1>scientific method of this stuff. You guys actually did a

0:36:05.680 --> 0:36:08.879
<v Speaker 1>podcast on the scientific method, so you should know that

0:36:08.960 --> 0:36:11.600
<v Speaker 1>at best you can show a particular theory is supported

0:36:11.600 --> 0:36:14.840
<v Speaker 1>by existing data and not contradicted by anything we know

0:36:14.920 --> 0:36:17.200
<v Speaker 1>of at the time. But there's a reason that ultra

0:36:17.280 --> 0:36:20.479
<v Speaker 1>successful theories like Newton's theory of gravity hind science. Theory

0:36:20.480 --> 0:36:24.719
<v Speaker 1>of relativity are still theories. They could be completely discredited

0:36:24.920 --> 0:36:27.480
<v Speaker 1>by a single piece of data contradicting them. So the

0:36:27.480 --> 0:36:29.239
<v Speaker 1>whole idea of taking a body of fact saying it's

0:36:29.239 --> 0:36:32.919
<v Speaker 1>settled is far more political concept than scientific one. While

0:36:32.960 --> 0:36:35.120
<v Speaker 1>people with various viewpoints in the subject would like to

0:36:35.160 --> 0:36:39.960
<v Speaker 1>have someplace to plant their ideological flag, saying something is

0:36:40.040 --> 0:36:43.640
<v Speaker 1>indisputedly true as opposed to probably false is simply not

0:36:43.760 --> 0:36:46.880
<v Speaker 1>something science and the scientific method is equipped to do.

0:36:47.480 --> 0:36:50.200
<v Speaker 1>In short, science has never settled. You cannot simply say

0:36:50.200 --> 0:36:52.640
<v Speaker 1>this is true, move on. That's not how it works.

0:36:53.600 --> 0:36:56.319
<v Speaker 1>And that is from Spencer Carpenter right here in our

0:36:56.360 --> 0:36:59.839
<v Speaker 1>own Smyrna, Georgia. We're not in St. Well, I mean

0:37:00.360 --> 0:37:05.360
<v Speaker 1>it's it's nearby. What I just did is what Spencer

0:37:05.440 --> 0:37:08.640
<v Speaker 1>just did. Spencer, I was using a literary device. I

0:37:08.680 --> 0:37:12.320
<v Speaker 1>was actually using the same type of argument that science

0:37:12.400 --> 0:37:16.960
<v Speaker 1>that non science climate deniers use against scientists. I was

0:37:17.120 --> 0:37:21.280
<v Speaker 1>basically saying, like, it's done, drop it. There's enough science

0:37:21.320 --> 0:37:25.920
<v Speaker 1>there to say you're you're you're wrong. Let's move on

0:37:26.080 --> 0:37:28.399
<v Speaker 1>and just all accept that climate science is going it's

0:37:28.400 --> 0:37:31.919
<v Speaker 1>a layoff. So that was a clever ruse. It wasn't

0:37:31.960 --> 0:37:34.759
<v Speaker 1>a ruse at all. It was it was just I

0:37:34.840 --> 0:37:38.240
<v Speaker 1>was not being literal like apparently, which is what Spencer

0:37:38.280 --> 0:37:42.480
<v Speaker 1>deals in literal terms. Uh, if you want to take

0:37:42.560 --> 0:37:45.200
<v Speaker 1>us to test because you are overly literal, we want

0:37:45.239 --> 0:37:48.080
<v Speaker 1>to hear from you. You can tweet to us at

0:37:48.239 --> 0:37:51.480
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0:37:51.560 --> 0:37:54.120
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0:37:54.200 --> 0:37:56.719
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0:37:56.760 --> 0:37:59.040
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0:37:59.080 --> 0:38:04.720
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0:38:04.719 --> 0:38:06.600
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