1 00:00:00,160 --> 00:00:04,120 Speaker 1: Maderna, rising after the pharmaceutical manufacturer reported fourth quarter revenue 2 00:00:04,160 --> 00:00:06,120 Speaker 1: the beat estimates. The company is saying it captured a 3 00:00:06,160 --> 00:00:09,120 Speaker 1: greater share of the covid vaccine market in the fall. 4 00:00:09,400 --> 00:00:12,320 Speaker 1: What It also expects regulators to approve its second commercial 5 00:00:12,320 --> 00:00:16,239 Speaker 1: product this year, a vaccine for RSV CEO Stephan Bansal 6 00:00:16,360 --> 00:00:19,239 Speaker 1: called in twenty twenty three a quote year of transition 7 00:00:19,640 --> 00:00:22,560 Speaker 1: as we adapted to the endemic market. Stephane a place 8 00:00:22,600 --> 00:00:24,400 Speaker 1: to say, catch u up with us again. It's definitely 9 00:00:24,440 --> 00:00:26,400 Speaker 1: been a wonderful front of this program over the last 10 00:00:26,440 --> 00:00:28,280 Speaker 1: year or so. It's great to catch up with you again, sir. 11 00:00:28,520 --> 00:00:30,240 Speaker 1: I just want to go to that market share story 12 00:00:30,280 --> 00:00:33,080 Speaker 1: around COVID vaccines. How did you do that? Where did 13 00:00:33,080 --> 00:00:34,279 Speaker 1: that come from? 14 00:00:34,840 --> 00:00:35,960 Speaker 2: So a lot of hard. 15 00:00:35,880 --> 00:00:40,760 Speaker 3: Work and also being able to communicate two doctors that 16 00:00:40,840 --> 00:00:43,800 Speaker 3: the two amount vaccines are not the same, and so 17 00:00:43,840 --> 00:00:46,239 Speaker 3: if you look at the real world evidence, we have 18 00:00:46,280 --> 00:00:50,239 Speaker 3: actually less hospitalization of people on the modern vaccine than 19 00:00:50,240 --> 00:00:54,520 Speaker 3: the over vaccine. We've also been partnering with pharmacies to 20 00:00:54,560 --> 00:00:56,680 Speaker 3: make sure we get the message out. So the team 21 00:00:56,720 --> 00:00:59,160 Speaker 3: has done a lot of different activities to ensure that 22 00:00:59,480 --> 00:01:01,600 Speaker 3: we get the share that we think we deserve. We 23 00:01:01,640 --> 00:01:04,959 Speaker 3: had thirty percent share in twenty twenty two, and we're 24 00:01:05,040 --> 00:01:07,640 Speaker 3: very pleased to have forty eight percent share in the 25 00:01:07,640 --> 00:01:08,840 Speaker 3: fall of twenty twenty four. 26 00:01:09,319 --> 00:01:13,160 Speaker 4: Stefan, do your investors still ask about COVID vaccines or 27 00:01:13,160 --> 00:01:16,720 Speaker 4: are they're much more interested in, say a melanoma vaccine 28 00:01:16,840 --> 00:01:20,320 Speaker 4: or some sort of using this technology to prevent cancer. 29 00:01:21,560 --> 00:01:22,120 Speaker 2: I mean both. 30 00:01:22,160 --> 00:01:25,200 Speaker 3: If you think about MODERNA, very much more to MODERNA 31 00:01:25,240 --> 00:01:27,600 Speaker 3: than COVID. So on the one hand, they want to 32 00:01:27,640 --> 00:01:29,479 Speaker 3: understand the COVID sales and how we're going to grow 33 00:01:29,520 --> 00:01:32,760 Speaker 3: the COVID sales and layer on that ursv sales and 34 00:01:32,760 --> 00:01:36,000 Speaker 3: the food sales because the respiratory franchise is going to 35 00:01:36,000 --> 00:01:39,120 Speaker 3: be a nand court to MODERNA forever because those virus 36 00:01:39,200 --> 00:01:41,160 Speaker 3: are not leaving the planet. But of course we are 37 00:01:41,240 --> 00:01:42,840 Speaker 3: very excited about the future. I mean, we have a 38 00:01:42,959 --> 00:01:46,000 Speaker 3: nine product in le search pipe plane if liing cancer. 39 00:01:46,480 --> 00:01:49,640 Speaker 3: But also you know we are genetic disease, and so 40 00:01:49,680 --> 00:01:52,120 Speaker 3: it's a very exciting time for MODERNA because they're getting 41 00:01:52,440 --> 00:01:55,360 Speaker 3: the existing products, but they're looking forward to the sales 42 00:01:55,440 --> 00:01:57,120 Speaker 3: growth delivered by the pipeline. 43 00:01:57,240 --> 00:01:59,040 Speaker 4: So on one hand, when you talk when you talk 44 00:01:59,080 --> 00:02:02,440 Speaker 4: about RSV, are we talk about COVID. There's the question 45 00:02:02,640 --> 00:02:05,240 Speaker 4: we were talking about regulatory risk, the regulatory boon of 46 00:02:05,280 --> 00:02:08,080 Speaker 4: say the CDC is coming out and recommending that everybody 47 00:02:08,160 --> 00:02:11,360 Speaker 4: get these shots every year or mandating it for certain positions. 48 00:02:11,520 --> 00:02:13,600 Speaker 4: Are you expecting that to be the case with things 49 00:02:13,680 --> 00:02:14,240 Speaker 4: like RSV? 50 00:02:15,639 --> 00:02:17,800 Speaker 3: I mean, if you're about ours, it is mostly a 51 00:02:17,919 --> 00:02:21,720 Speaker 3: risk for the elderly and the very young children. So 52 00:02:21,840 --> 00:02:24,639 Speaker 3: I think the current guidelines know of vaccinations for the 53 00:02:24,639 --> 00:02:26,040 Speaker 3: elderly makes a lot of sense. 54 00:02:26,639 --> 00:02:29,160 Speaker 2: And we were all very surprised. 55 00:02:28,720 --> 00:02:31,400 Speaker 3: Actually about the number of people who got the RSB 56 00:02:31,520 --> 00:02:32,280 Speaker 3: shot last year. 57 00:02:32,320 --> 00:02:36,200 Speaker 2: You know, it was much higher than any analysts forecasted. 58 00:02:36,720 --> 00:02:38,800 Speaker 3: So we're very excited because not only with a great 59 00:02:38,840 --> 00:02:43,360 Speaker 3: product in efficacy, a very good safety profile, but if 60 00:02:43,400 --> 00:02:45,959 Speaker 3: a product is approved by the regulators, which could come 61 00:02:46,000 --> 00:02:49,160 Speaker 3: as early as mid twelve, that's the AfD to do. 62 00:02:49,240 --> 00:02:53,560 Speaker 3: For date, we could be the only product available to 63 00:02:53,639 --> 00:02:57,680 Speaker 3: healthcare professional in a pre fill syringe, and that's really important. 64 00:02:57,760 --> 00:02:59,959 Speaker 3: As you know, there's a lot of label short helps 65 00:03:00,080 --> 00:03:05,160 Speaker 3: in healthcare professional, especially very cute in pharmacy retail chains, 66 00:03:05,440 --> 00:03:08,120 Speaker 3: and if you think about the full season the pharmacies 67 00:03:08,160 --> 00:03:08,840 Speaker 3: are very busy. 68 00:03:08,880 --> 00:03:10,560 Speaker 2: They have to do the usual work. 69 00:03:10,840 --> 00:03:14,440 Speaker 3: There's a lot of products for people and through shots 70 00:03:14,480 --> 00:03:18,079 Speaker 3: and COVID shots and now OURSV shots, but the two 71 00:03:18,080 --> 00:03:21,400 Speaker 3: products available on the market are pretty tedious. One of 72 00:03:21,440 --> 00:03:23,800 Speaker 3: them is nine steps of preparation. The O one is 73 00:03:23,840 --> 00:03:27,639 Speaker 3: four steps of proporation when Moderna again, if approved, will 74 00:03:27,680 --> 00:03:28,560 Speaker 3: be the only. 75 00:03:28,360 --> 00:03:30,320 Speaker 2: Product that is pre fill syringe. 76 00:03:30,360 --> 00:03:32,320 Speaker 3: You take it out of the fridge, you clean the arm, 77 00:03:32,600 --> 00:03:34,880 Speaker 3: you inject it, you put a bat day, you are done. 78 00:03:35,120 --> 00:03:37,680 Speaker 3: I really believe that healthcare professional are going to be 79 00:03:37,680 --> 00:03:39,320 Speaker 3: delighted with our product, Sepan. 80 00:03:39,400 --> 00:03:41,280 Speaker 5: That's what I want to ask you. You mentioned COVID 81 00:03:41,320 --> 00:03:44,640 Speaker 5: flow RSV. So many vaccines individuals need to get in 82 00:03:44,680 --> 00:03:46,600 Speaker 5: the winter, so if you had this one shot, it 83 00:03:46,600 --> 00:03:50,400 Speaker 5: would save a lot of time and frankly, it'd be 84 00:03:50,440 --> 00:03:52,720 Speaker 5: a lot easier probably in appetizing people to actually go 85 00:03:52,760 --> 00:03:54,760 Speaker 5: out and get it. But what is the timeline when 86 00:03:54,800 --> 00:03:56,520 Speaker 5: can we see that actually go to market? 87 00:03:57,240 --> 00:04:00,400 Speaker 3: So that's one of the other exciting news coming for 88 00:04:00,480 --> 00:04:02,960 Speaker 3: twenty four is we shared last year the phase two 89 00:04:03,000 --> 00:04:06,120 Speaker 3: data of our COVID plus through combo in a single dose. 90 00:04:06,680 --> 00:04:09,960 Speaker 3: We should see this year the phase three data. Based 91 00:04:10,000 --> 00:04:12,480 Speaker 3: on the platform that we have and what we've seen 92 00:04:12,520 --> 00:04:16,000 Speaker 3: with COVID, with URSV and THROUGH, I expect the Phase. 93 00:04:15,840 --> 00:04:16,839 Speaker 2: Three to be positive. 94 00:04:17,279 --> 00:04:19,599 Speaker 3: If it is positive, we will finally to regulate all 95 00:04:19,760 --> 00:04:22,320 Speaker 3: so you could see these available in pharmacies as early 96 00:04:22,360 --> 00:04:25,640 Speaker 3: as a fall of twenty five. So that's another exciting differentiation. 97 00:04:25,720 --> 00:04:30,280 Speaker 3: We will have use traditional THROUGH playoffs and traditional COVID playoffs. 98 00:04:30,360 --> 00:04:32,080 Speaker 1: Stephan, I know we're against the clock with you. You've 99 00:04:32,080 --> 00:04:34,120 Speaker 1: got a busy morning. I just want to squeeze the 100 00:04:34,160 --> 00:04:37,080 Speaker 1: same the RSV shot. What are you learning about the 101 00:04:37,160 --> 00:04:40,760 Speaker 1: durability the protection offers because as we understand based on 102 00:04:40,920 --> 00:04:43,320 Speaker 1: recent reports coming from you, maybe it doesn't last as 103 00:04:43,320 --> 00:04:46,920 Speaker 1: long as the competitor and they're offering does. So it 104 00:04:46,960 --> 00:04:49,800 Speaker 1: makes me wonder does that effect approval? Is that going 105 00:04:49,839 --> 00:04:53,720 Speaker 1: to affect your competition against that competitor as you want 106 00:04:53,720 --> 00:04:55,280 Speaker 1: to roll that one out. 107 00:04:56,400 --> 00:04:58,599 Speaker 3: Actually, if you look at the data, we're very confident 108 00:04:58,640 --> 00:05:00,680 Speaker 3: about our profile and if you look the data of 109 00:05:00,720 --> 00:05:02,600 Speaker 3: your vaccine, they also wane. 110 00:05:03,040 --> 00:05:03,919 Speaker 2: And so if you. 111 00:05:03,920 --> 00:05:06,120 Speaker 3: Look at what we're going to have in the marketplace, 112 00:05:06,160 --> 00:05:08,159 Speaker 3: I think it's going to be very very similar to 113 00:05:08,160 --> 00:05:09,240 Speaker 3: what's available today. 114 00:05:09,560 --> 00:05:10,800 Speaker 2: So I don't think that's going to be an issue 115 00:05:10,880 --> 00:05:11,280 Speaker 2: at all. 116 00:05:11,480 --> 00:05:14,000 Speaker 1: Stephan got to leave it there. We promised that you'd 117 00:05:14,120 --> 00:05:15,800 Speaker 1: escape for the band seven thirty eight, so you can. 118 00:05:15,839 --> 00:05:19,240 Speaker 1: Stefan Bansal, the Maturner CEO. Thanks Stefan, great to catch out. 119 00:05:19,240 --> 00:05:19,720 Speaker 1: Thank you, sir,