WEBVTT - What’s at Stake

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<v Speaker 1>Pushkin. Welcome to a Brave New Planet. My name is

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<v Speaker 1>Eric Lander. I'm your host for this new podcast. In

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<v Speaker 1>the upcoming episodes, we'll explore frontiers of science and technology

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<v Speaker 1>that are both exciting and challenging. Artificial intelligence that's unleashing

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<v Speaker 1>artistic creativity, but also enabling deep fakes that undermine truth

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<v Speaker 1>and democracy. A plan to modify the Earth's atmosphere to

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<v Speaker 1>hold off climate change that might buy time or might

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<v Speaker 1>keep us from solving the real problem. A new genetic

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<v Speaker 1>technology for engineering nature that might prevent malaria but might

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<v Speaker 1>get out of hand. Computer algorithms that can diagnose diseases,

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<v Speaker 1>tell companies who to hire, and judges had a sentence,

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<v Speaker 1>but might also automate or human biases. And we'll ask

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<v Speaker 1>whether it's time to turn war over to robots. We'll

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<v Speaker 1>look at the amazing upsides and also ask what could

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<v Speaker 1>possibly go wrong. But for this short first episode, I

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<v Speaker 1>thought i'd better explain who I am and why I'm here.

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<v Speaker 1>I'm a scientist. I grew up in New York City,

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<v Speaker 1>a product of the public schools, where I fell in

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<v Speaker 1>love with math. Not long after I did my PhD

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<v Speaker 1>in mathematics, I became captivated by genetics. By luck, that

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<v Speaker 1>was just a few years before biologists began dreaming about

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<v Speaker 1>reading out the complete human genetic code, all three billion

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<v Speaker 1>letters of DNA. I got involved in this crazy idea

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<v Speaker 1>called the Human gene Project, and became one of the

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<v Speaker 1>leaders of that international collaboration. As the work neared its end,

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<v Speaker 1>I helped launch a research institute, the Broad Institute of

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<v Speaker 1>MT and Harvard, that I still lead today, to apply

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<v Speaker 1>that same collaborative spirit to help a new generation of

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<v Speaker 1>remarkable scientists propel the understanding and treatment of human diseases

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<v Speaker 1>outside the laboratory. I've always cared a lot about how

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<v Speaker 1>science affects the world. For eight years, I also co

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<v Speaker 1>chaired the President's Council of Advisors on Science and Technology

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<v Speaker 1>for the Obama White House. We got a chance to

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<v Speaker 1>wrestle with some of the nation's biggest opportunities and problems,

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<v Speaker 1>from energy to influenza, cybersecurity to aging, and through it all,

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<v Speaker 1>I've continued to teach introbiology to MIT students, who every

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<v Speaker 1>year restore my faith in the future. But that future

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<v Speaker 1>is on the line today in ways it's never been before.

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<v Speaker 1>The decisions we make or don't make will affect us

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<v Speaker 1>all for generations to come. So to kick off Brave

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<v Speaker 1>New Planet, I wanted to talk with someone who has

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<v Speaker 1>boundless curiosity and might help us think about what's at stake.

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<v Speaker 1>I reached out to Malcolm Gladwell. He's the author of

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<v Speaker 1>books like Talking to Strangers and Outliers and the host

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<v Speaker 1>of the podcast Revisionist History. To my delight, he agreed

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<v Speaker 1>to join us. Malcolm Gladwell, Welcome to Brave New Planet.

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<v Speaker 1>Thank you, Eric. I am delighted to be here and

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<v Speaker 1>fascinated to learn more about your new podcast. But before

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<v Speaker 1>we get into it, I wanted to talk a little

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<v Speaker 1>bit about you. I'm very curious about how your initial

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<v Speaker 1>ideas about science were formed and why what led you

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<v Speaker 1>into this world in the first place. You know, looking

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<v Speaker 1>back growing up in New York as a kid in

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<v Speaker 1>the nineteen sixties, it was pretty amazing. I was raised

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<v Speaker 1>by my mom and we didn't have a lot of money,

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<v Speaker 1>but she figured out everything free and everything cheap that

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<v Speaker 1>you could do, dragonist to museums. She let us stay

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<v Speaker 1>home and watch all the space launches, and then nineteen

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<v Speaker 1>sixty four sixty five was the World's Fair, the New

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<v Speaker 1>York City World's Fair, and that was amazing. There was

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<v Speaker 1>this the Unisphere, the big globe that was the symbol

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<v Speaker 1>of the World's Fair. It's it's the thing that gets

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<v Speaker 1>destroyed in Men in Black at the end of the movie,

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<v Speaker 1>and there was a guy in a jet pack who

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<v Speaker 1>flew over the unisphere and they told us all we

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<v Speaker 1>would be going to work in jetpacks. I still am

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<v Speaker 1>waiting for my jetpack. But there were all these other things.

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<v Speaker 1>There was like the ge Carousel of Progress where they

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<v Speaker 1>were singing There's a great, big, beautiful tomorrow. And there

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<v Speaker 1>was Belle Labs premiering the picture phone, and du Pont

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<v Speaker 1>with its wonderful world of Chemistry, which I think became

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<v Speaker 1>the better slogan better living through chemistry. And they had

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<v Speaker 1>this time capsule that we're going to dig up in

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<v Speaker 1>five thousand years. And it was also the era of

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<v Speaker 1>Star Trek, where everybody, all races and genders, we were

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<v Speaker 1>going to go out together and boldly go and so

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<v Speaker 1>it was a period of like infinite possibility, amazing optimism

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<v Speaker 1>about what you could do in the world. There are

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<v Speaker 1>obviously lots of tensions bubbling under the surface, but as

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<v Speaker 1>a seven eight year old kid I wasn't wear any

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<v Speaker 1>of that yet, and so I think I was formed

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<v Speaker 1>in this world that thought science was going to be

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<v Speaker 1>incredibly important to progress and the world was gonna it

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<v Speaker 1>was just going to become a better and better place.

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<v Speaker 1>I'm amazed, like in your description of that, how frictionless

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<v Speaker 1>your access to knowledge as a kid was seems to

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<v Speaker 1>have been. I mean, all the stuff's on your doorstep,

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<v Speaker 1>like the New York's Fairest. I mean, I don't know

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<v Speaker 1>what subway you're taking, or maybe a couple of buses,

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<v Speaker 1>but but I mean the point is, like, you don't

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<v Speaker 1>have to have a lot of money. You're going to

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<v Speaker 1>lost a dollar for kids to get in. Yeah, now

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<v Speaker 1>dollar was worth more than but still, you know, my

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<v Speaker 1>mom dragged us fourteen times to the World's Fair and

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<v Speaker 1>it was she was amazing. Fourteen times. I love it.

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<v Speaker 1>You remember how many times? Oh yeah, So you have

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<v Speaker 1>this coming out of your childhood, you inherit, this sense

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<v Speaker 1>of infinite possibility. What happens to that sense as you

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<v Speaker 1>get older? Is it still there? Well? It's interesting, I mean,

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<v Speaker 1>where does that sense come from? An infinite possibility? It's

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<v Speaker 1>it's no accident that the nineteen sixties are like that.

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<v Speaker 1>It's after World War Two, where science played a big

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<v Speaker 1>role in winning the war, radar, early computers, penicillin, of course,

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<v Speaker 1>atomic bombs, and the US makes this decision after the

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<v Speaker 1>war that science is going to be a cornerstone of

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<v Speaker 1>society going forward, that we're going to fund science at universities,

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<v Speaker 1>and we're gonna train people, and we'll have this virtuous

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<v Speaker 1>cycle of public knowledge producing technologies and wars and companies.

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<v Speaker 1>And then of course, nine months after I'm born, Sputnik

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<v Speaker 1>goes up. I don't remember it, but I know it

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<v Speaker 1>was exactly nine months after I was born, and like

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<v Speaker 1>everything goes into overdrive. Science is central to the survival

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<v Speaker 1>of the country. We pass laws for science education, we

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<v Speaker 1>start the space race to get a man on the

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<v Speaker 1>moon first. So you know, this is the world that

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<v Speaker 1>shaped that New York City of the nineteen sixties was

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<v Speaker 1>the sense that science was going to discover what's true,

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<v Speaker 1>technology was going to figure out what's possible, and society

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<v Speaker 1>reaps the benefits. And that assumption, that idea that the

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<v Speaker 1>scientific method, you know, you figure out what's true by evidence,

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<v Speaker 1>not authority. It's all about honesty, not advocacy. There was

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<v Speaker 1>a set of assumptions that underlay that world where this

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<v Speaker 1>country really bought into the ideas of science, and it

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<v Speaker 1>paid off amazing dividends. You know, through the rest of

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<v Speaker 1>the twentieth century. You think about all the things that

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<v Speaker 1>happened from what had to have been a bit of

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<v Speaker 1>a crazy bet. The US didn't invest in science a

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<v Speaker 1>lot before the war. But afterwards you look at the

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<v Speaker 1>things that start happening. You get polio vaccines, measles, and

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<v Speaker 1>smallpox vaccines and eradicate smallpox. And you get computer technology

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<v Speaker 1>and the Internet and GPS systems and like Google searches

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<v Speaker 1>come out of a National Science Foundation grant, and then

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<v Speaker 1>molecular biology and gene cloning and this Human Genome Project

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<v Speaker 1>I got very involved in, and onward and onward and onward,

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<v Speaker 1>and you get these industries that grow up around all

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<v Speaker 1>these things. So I think it paid off in huge ways.

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<v Speaker 1>And what's interesting is it's only accelerated since then in

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<v Speaker 1>terms of the science, even though there are a lot

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<v Speaker 1>of tensions, you know from the any of you of

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<v Speaker 1>the science. You look at the last two decades or

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<v Speaker 1>so and you start seeing, you know, artificial intelligence, we

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<v Speaker 1>can translate languages, by computers and spot lung cancers by computers,

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<v Speaker 1>and people are making self driving cars and quantum computers.

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<v Speaker 1>And in biology you have you know, new therapies for cancer, immunotherapies,

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<v Speaker 1>and this Human Genome project where we spent three billion

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<v Speaker 1>dollars to read one genome. It now costs a couple

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<v Speaker 1>hundred bucks to read a genome. There are technologies that

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<v Speaker 1>let you edit genomes like Crisper, and just keeps going

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<v Speaker 1>and going, and I think, if anything, it's accelerating in

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<v Speaker 1>terms of the science and the impact on society. I've

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<v Speaker 1>just curious, Eric, you've chosen to do this now? Is

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<v Speaker 1>there a reason why now? I mean, you could have

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<v Speaker 1>done this five years ago, You could have done this

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<v Speaker 1>five years from now. So there's something compelling you at

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<v Speaker 1>this moment in time. Yeah. Absolutely. It is so glaringly

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<v Speaker 1>out obvious that we are going to need science to

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<v Speaker 1>solve a lot of the problems ahead. Climate change. It's

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<v Speaker 1>in our face right now. It was theoretical to people,

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<v Speaker 1>but the last three or four years, it's so obvious

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<v Speaker 1>we're gonna have to solve that. The pandemic that we're

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<v Speaker 1>living through right now, it's clear there's no way to

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<v Speaker 1>solve pandemics without a lot more science than we've brought

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<v Speaker 1>to bear on it so far. And then I think

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<v Speaker 1>about things like Alzheimer's. It's going to be costing US

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<v Speaker 1>a trillion dollars a year as the usages, and we

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<v Speaker 1>really don't know how to do anything other than support people.

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<v Speaker 1>So we've got to come up with solutions, and those

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<v Speaker 1>solutions that got to come from science. I could go

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<v Speaker 1>on and on, and so it seemed like a moment

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<v Speaker 1>when we just had to decide are we going to

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<v Speaker 1>rally a world together around science. It's Matt Damon's famous

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<v Speaker 1>line from the movie The Martian when he branded on

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<v Speaker 1>Mars and he knows nobody's coming back for him soon,

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<v Speaker 1>and he says, I guess there's only one option. I'm

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<v Speaker 1>going to have to science the shit out of this.

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<v Speaker 1>We're gonna have to do that right now. And I

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<v Speaker 1>think the last several years have made that so apparent.

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<v Speaker 1>We really have to reconnect between science and society because

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<v Speaker 1>that connection is going to be so important going forward.

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<v Speaker 1>Do you think if you were an eight year old today,

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<v Speaker 1>you would have to describe what your eight year old

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<v Speaker 1>self today would think if is it the same sense

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<v Speaker 1>of infinite possibility. I think there's a frustration right now,

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<v Speaker 1>a sense that we're not doing all we can with this,

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<v Speaker 1>and there's a lot of reasons for it. The bright

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<v Speaker 1>shininess of science would discover the truth and technologies would

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<v Speaker 1>show us what's possible, and society would reap the benefits.

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<v Speaker 1>That simple social compact is getting frayed in some ways,

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<v Speaker 1>and there's a lot of different ways it's getting fred

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<v Speaker 1>it's not surprising that after sixty years things would would

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<v Speaker 1>begin to get a little tattered. But you know, if

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<v Speaker 1>you think about it, science sometimes conflicts with economic interests.

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<v Speaker 1>We began to see that companies might start attacking science

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<v Speaker 1>because they really don't like the answers. I think the

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<v Speaker 1>first case was when it became clear that cigarettes caused cancer,

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<v Speaker 1>and tobacco companies decided to pay people to put up

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<v Speaker 1>smoke screens and question the evidence. And then, of course,

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<v Speaker 1>climate changes is where we see it most today, where

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<v Speaker 1>despite massive amounts of evidence, the solutions just deny it.

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<v Speaker 1>You know, we've got massive wildfires in California, and we've

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<v Speaker 1>got wildfires a couple of years ago above the Arctic circle.

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<v Speaker 1>We got glaciers retreating powerful hurricanes, you know, the last

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<v Speaker 1>six years, the hottest years in history, and people just say, well,

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<v Speaker 1>you know, nothing to see here, that's all just a fluke.

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<v Speaker 1>And I think that that ability to not even have

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<v Speaker 1>to engage is one tension that we're trying to deal

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<v Speaker 1>with right now. Is is there a shared assumption that

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<v Speaker 1>we have to deal with the evidence. But then there's

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<v Speaker 1>other things. I think on science's side, sometimes science just

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<v Speaker 1>seems to overpromise, and sometimes probably does overpromise. There are

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<v Speaker 1>people who say, wait, wait a second, I thought you

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<v Speaker 1>were curing cancer. How come cancers not cured yet? I

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<v Speaker 1>think going overboard on promises and not giving people a

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<v Speaker 1>sense of the fact that, yeah, science is amazing, but

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<v Speaker 1>it takes a while to deliver can backfire. And I

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<v Speaker 1>think I think there's also people who you just want

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<v Speaker 1>answers to things and science doesn't have answers for them,

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<v Speaker 1>and they got to go seek them somewhere. Yeah, is

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<v Speaker 1>this kind of these kinds of ways what led you

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<v Speaker 1>to want to do a podcast? Well exactly, you know,

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<v Speaker 1>I think this compact between science and society is so important.

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<v Speaker 1>It's getting tattered and we have to do something about it,

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<v Speaker 1>and that requires drawing more people into hard problems and science.

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<v Speaker 1>We can't we can't ignore the fact that the problems

0:14:22.850 --> 0:14:27.810
<v Speaker 1>are hard. Sometimes these bright shiny futures that we talk

0:14:27.890 --> 0:14:32.970
<v Speaker 1>about we really get instead dystopian outcomes. Things really can

0:14:33.090 --> 0:14:36.650
<v Speaker 1>go wrong. The better living through chemistry can turn into

0:14:36.730 --> 0:14:40.570
<v Speaker 1>toxic waste. The Internet that's supposed to give us all

0:14:40.650 --> 0:14:45.450
<v Speaker 1>the world's information can bring us disinformation. You know. Social

0:14:45.490 --> 0:14:48.570
<v Speaker 1>media that's supposed to bring us together can tear us apart.

0:14:48.650 --> 0:14:51.930
<v Speaker 1>I know you're you're really interested in these topics yourself,

0:14:52.530 --> 0:14:55.290
<v Speaker 1>and I think there are times when when there's just

0:14:55.330 --> 0:14:59.970
<v Speaker 1>been failures of imagination to think about what could possibly

0:15:00.090 --> 0:15:04.090
<v Speaker 1>go wrong. Whatever the compact was in the nineteen sixties

0:15:04.810 --> 0:15:07.410
<v Speaker 1>where you kind of left it to the scientists and

0:15:07.410 --> 0:15:10.610
<v Speaker 1>the politicians to work at all out, We're now going

0:15:10.690 --> 0:15:13.610
<v Speaker 1>to need everybody on board. We're gonna need to open

0:15:13.650 --> 0:15:18.010
<v Speaker 1>this up to more people and recognize that science might

0:15:18.050 --> 0:15:20.610
<v Speaker 1>have a lot of answers about the science, but we're

0:15:20.610 --> 0:15:22.530
<v Speaker 1>not going to have all the answers about how it

0:15:22.570 --> 0:15:25.330
<v Speaker 1>should be applied in the world. And that was really

0:15:25.410 --> 0:15:28.410
<v Speaker 1>the heart of the podcast. If we really are now

0:15:28.690 --> 0:15:32.690
<v Speaker 1>all the stewards of a brave new planet, then we

0:15:33.010 --> 0:15:35.250
<v Speaker 1>got to figure out how to draw everybody in on

0:15:35.290 --> 0:15:39.810
<v Speaker 1>that and open it up. Would you describe yourself still

0:15:39.850 --> 0:15:44.090
<v Speaker 1>as an optimist? Oh, I am a tremendous optimist in

0:15:44.170 --> 0:15:48.930
<v Speaker 1>spite of lots of evidence to the contrary, because in

0:15:49.010 --> 0:15:51.810
<v Speaker 1>the end, I really don't see any alternative. So I

0:15:51.930 --> 0:15:57.530
<v Speaker 1>am a very realistic optimist. I think we're gonna need

0:15:57.570 --> 0:16:00.410
<v Speaker 1>to fight for truth. It's not a gimme like it

0:16:00.490 --> 0:16:04.330
<v Speaker 1>might have been a half century ago. I think we

0:16:04.370 --> 0:16:07.410
<v Speaker 1>are gonna need to bring everybody in to help make

0:16:07.530 --> 0:16:11.370
<v Speaker 1>decisions about how we should use this. It's not going

0:16:11.450 --> 0:16:13.850
<v Speaker 1>to be easy. And uh, you know, there's nothing about

0:16:13.890 --> 0:16:18.730
<v Speaker 1>the podcast that's advocating specific answers to anything. It's it's

0:16:18.730 --> 0:16:24.290
<v Speaker 1>really meant to model smart, thoughtful, passionate people struggling with

0:16:24.330 --> 0:16:26.610
<v Speaker 1>what do we do with our future? And so it's

0:16:26.650 --> 0:16:30.010
<v Speaker 1>meant to invite people into that because you know, in

0:16:30.090 --> 0:16:33.450
<v Speaker 1>my most optimistic self, that's how we make it through

0:16:33.570 --> 0:16:38.410
<v Speaker 1>is we we all work together to struggle through hard

0:16:38.490 --> 0:16:43.650
<v Speaker 1>problems that have amazing upsides, maybe big downsides, and together

0:16:43.730 --> 0:16:46.610
<v Speaker 1>we make it through. And you know, these are things

0:16:46.690 --> 0:16:49.810
<v Speaker 1>that they're just too big to fit in a tweet.

0:16:50.490 --> 0:16:54.890
<v Speaker 1>And I'm really interested. I know you are in ideas

0:16:54.890 --> 0:16:57.330
<v Speaker 1>that are too big to fit in a tweet but

0:16:57.410 --> 0:16:59.610
<v Speaker 1>will end up, you know, shaping the future in a

0:16:59.650 --> 0:17:02.170
<v Speaker 1>big way. And so that that was the heart of

0:17:02.170 --> 0:17:05.050
<v Speaker 1>the podcast. Has there been a moment maybe not doing

0:17:05.090 --> 0:17:09.570
<v Speaker 1>this podcast, but when you're dealings with others scientists in

0:17:09.650 --> 0:17:12.330
<v Speaker 1>fields not your own? Is the rare for a moment

0:17:12.370 --> 0:17:15.290
<v Speaker 1>when you're over your head? Will you say I have

0:17:15.330 --> 0:17:19.130
<v Speaker 1>no idea what these guys talking about? Oh? Yeah, oh yeah.

0:17:19.170 --> 0:17:22.770
<v Speaker 1>Frequently there were occasional times I was really deeply an

0:17:22.770 --> 0:17:25.570
<v Speaker 1>expert in the subject, but you know, many many other

0:17:25.610 --> 0:17:28.330
<v Speaker 1>different things. You know, I'm not an expert, and so

0:17:28.410 --> 0:17:31.130
<v Speaker 1>I think what I had to learn was the right

0:17:31.210 --> 0:17:34.490
<v Speaker 1>kind of scientific humility to ask dumb questions and say

0:17:34.810 --> 0:17:38.570
<v Speaker 1>what exactly does that mean? And you can learn a

0:17:38.570 --> 0:17:41.570
<v Speaker 1>lot from that. Yeah, yeah, I am. I am. That

0:17:41.650 --> 0:17:44.850
<v Speaker 1>actually is a lovely place to end. I'm in total

0:17:44.930 --> 0:17:47.570
<v Speaker 1>agreement with you. I think the key to being an

0:17:47.570 --> 0:17:53.450
<v Speaker 1>effective journalist, explainer, podcast host, whatever is the willingness to

0:17:53.530 --> 0:17:57.970
<v Speaker 1>ask really dumb questions. Indeed, thank you so much. This

0:17:58.010 --> 0:18:00.290
<v Speaker 1>is I cannot tell you how excited I am to

0:18:00.370 --> 0:18:02.650
<v Speaker 1>listen to this and how delighted I am that you

0:18:02.730 --> 0:18:07.530
<v Speaker 1>have you of all people, have decided to tackle this subject.

0:18:07.530 --> 0:18:11.490
<v Speaker 1>It's it is greatly needed. Oh Malcolm, thanks so much

0:18:11.530 --> 0:18:15.330
<v Speaker 1>for helping us kick off this first episode. Thank you

0:18:15.330 --> 0:18:19.890
<v Speaker 1>America and to all of you listeners. Come join us

0:18:20.050 --> 0:18:25.330
<v Speaker 1>for episode two, where we'll hear President Richard Nixon console

0:18:25.490 --> 0:18:29.850
<v Speaker 1>a grieving nation about the tragic outcome of America's failed

0:18:29.890 --> 0:18:33.930
<v Speaker 1>mission to land a man on the Moon. Good evening,

0:18:34.170 --> 0:18:38.530
<v Speaker 1>my fellow Americans. Fakes has ordained that the men who

0:18:38.570 --> 0:18:42.650
<v Speaker 1>went to the Moon to explore and peace will stay

0:18:42.690 --> 0:18:47.370
<v Speaker 1>on the Moon to rest in peace. These brave men,

0:18:48.370 --> 0:18:54.170
<v Speaker 1>Meal Armstrong and Edwin Auburn know that there's no pup

0:18:54.730 --> 0:19:00.490
<v Speaker 1>for their recovery. Deep Fakes next time on Brave New Planet.

0:19:02.610 --> 0:19:04.770
<v Speaker 1>Brave New Planet is a co production of the Broad

0:19:04.850 --> 0:19:07.930
<v Speaker 1>Institute of MT and Harvard Pushkin Industries in the Boston

0:19:08.010 --> 0:19:12.370
<v Speaker 1>Globe support from the Alfred P. Sloane Foundation. Our show

0:19:12.450 --> 0:19:15.930
<v Speaker 1>is produced by Rebecca Lee Douglas with Mary Dow. Theme

0:19:15.970 --> 0:19:19.730
<v Speaker 1>song composed by Ned Porter, mastering and sound designed by

0:19:19.810 --> 0:19:23.290
<v Speaker 1>James Garver, fact checking by Joseph Fridman, and a Stitt

0:19:23.290 --> 0:19:27.810
<v Speaker 1>and Enchant. Special thanks to Christine Heenan and Rachel Roberts

0:19:27.810 --> 0:19:32.050
<v Speaker 1>at Clarendon Communications, to Lee McGuire, Kristen Zarelli and Justine

0:19:32.130 --> 0:19:36.050
<v Speaker 1>Levin Allerhand at the Broad, Tamil o'bell and Heather Faine

0:19:36.050 --> 0:19:39.970
<v Speaker 1>at Pushkin, And to Eli and Edy Brode who made

0:19:39.970 --> 0:19:44.930
<v Speaker 1>the Broad Institute possible. This is brave new planet. I'm

0:19:45.010 --> 0:19:45.570
<v Speaker 1>Eric Lander.