1 00:00:08,720 --> 00:00:14,080 Speaker 1: Katie, what is your favorite color? I'm gonna say blue. Well, 2 00:00:14,120 --> 00:00:16,759 Speaker 1: you can't just say blue. There's like a million different 3 00:00:16,760 --> 00:00:21,079 Speaker 1: shades of blue. Okay, I guess say more blue green 4 00:00:21,200 --> 00:00:24,319 Speaker 1: than a navy blue. Oh, you can do better than that. 5 00:00:24,400 --> 00:00:28,080 Speaker 1: Pretend you're like writing copy for a paint catalog. Give 6 00:00:28,160 --> 00:00:32,760 Speaker 1: us a really descriptive name. Okay, something like ce foam 7 00:00:32,840 --> 00:00:39,360 Speaker 1: mermaid tears or radiant peacock party. Now we're talking, But 8 00:00:39,479 --> 00:00:41,760 Speaker 1: for this podcast, can you give us like a really 9 00:00:41,800 --> 00:00:45,000 Speaker 1: good physics name for your shade of blue? How about 10 00:00:45,520 --> 00:00:51,960 Speaker 1: sparsely hydrogenated blue dwarf. That sounds awesome for me. I'm 11 00:00:51,960 --> 00:00:55,160 Speaker 1: personally looking forward to the day when somebody launches physics 12 00:00:55,160 --> 00:00:57,240 Speaker 1: paint colors and I can go to the store and 13 00:00:57,280 --> 00:01:01,960 Speaker 1: ask for a gallon of sultry supernova sky arlette. That 14 00:01:02,080 --> 00:01:19,880 Speaker 1: might blow up your her face. Hi. I'm Daniel. I'm 15 00:01:19,920 --> 00:01:24,119 Speaker 1: a particle physicist and a professor at UC Irvine, and 16 00:01:24,280 --> 00:01:27,800 Speaker 1: I've never met a color I didn't like. And I'm Katie. 17 00:01:27,880 --> 00:01:30,520 Speaker 1: I'm stepping in for Jorge this week. I am the 18 00:01:30,520 --> 00:01:34,800 Speaker 1: host of Creature Feature and I like all colors all 19 00:01:34,800 --> 00:01:40,280 Speaker 1: the time simultaneously. It makes me hesitate to ask what 20 00:01:40,440 --> 00:01:47,520 Speaker 1: your closet looks like. Katie Brown, I remember wondering as 21 00:01:47,520 --> 00:01:50,440 Speaker 1: a kid if there was a possibility for you to 22 00:01:50,680 --> 00:01:53,680 Speaker 1: imagine a color you hadn't seen before, you know, like, 23 00:01:53,760 --> 00:01:56,520 Speaker 1: if you thought hard enough, could you invent a color 24 00:01:56,640 --> 00:01:59,960 Speaker 1: in your mind that didn't exist out there in the world. 25 00:02:00,320 --> 00:02:02,240 Speaker 1: What do you think do you think that's possible? Yeah? 26 00:02:02,280 --> 00:02:04,800 Speaker 1: I mean I used to have that same exact thought, 27 00:02:05,000 --> 00:02:08,959 Speaker 1: thinking of, well, couldn't there be other colors than what 28 00:02:09,200 --> 00:02:12,760 Speaker 1: we know on the spectrum? And what would that be like? 29 00:02:12,919 --> 00:02:15,920 Speaker 1: And I would imagine that that experience of this new 30 00:02:15,960 --> 00:02:20,840 Speaker 1: color might be something beyond just vision, maybe accompanied by 31 00:02:20,840 --> 00:02:24,960 Speaker 1: a feeling like a tingling or something, I like the 32 00:02:24,960 --> 00:02:27,679 Speaker 1: connection of the senses. There. Maybe you see a new 33 00:02:27,760 --> 00:02:30,080 Speaker 1: kind of fruit and it has a new kind of taste, 34 00:02:30,360 --> 00:02:33,040 Speaker 1: and it opens up a whole new branch of philosophy. 35 00:02:33,360 --> 00:02:37,440 Speaker 1: Now we're getting into synesthesia territory exactly. But this question 36 00:02:37,440 --> 00:02:39,920 Speaker 1: of color is it really deep and fascinating one because 37 00:02:39,960 --> 00:02:43,560 Speaker 1: it extends all the way from philosophy, like what is 38 00:02:43,560 --> 00:02:46,720 Speaker 1: it like to experience a color? Down to biology how 39 00:02:46,760 --> 00:02:50,880 Speaker 1: does the human eye respond to photons? And finally to physics, 40 00:02:50,880 --> 00:02:54,200 Speaker 1: what exactly is a red photon and a blue photon 41 00:02:54,280 --> 00:02:56,560 Speaker 1: and a green photon, and that's exactly the kind of 42 00:02:56,560 --> 00:02:59,959 Speaker 1: topic we love to dive into on this podcast. So well, 43 00:03:00,000 --> 00:03:03,200 Speaker 1: welcome to the podcast Daniel and Jorge Exploding the Universe, 44 00:03:03,240 --> 00:03:05,639 Speaker 1: in which we ask the deepest, the reddest, the bluest, 45 00:03:05,680 --> 00:03:09,480 Speaker 1: the whitest, the darkest questions about the nature of the universe. 46 00:03:09,760 --> 00:03:11,760 Speaker 1: We ask questions that go all the way from your 47 00:03:11,760 --> 00:03:14,240 Speaker 1: eyeball deep deep down through your brain, and all the 48 00:03:14,240 --> 00:03:17,440 Speaker 1: way into your soul, whether or not it exists. I'm 49 00:03:17,480 --> 00:03:21,480 Speaker 1: so excited to smash biology and physics together and create 50 00:03:21,600 --> 00:03:23,960 Speaker 1: some kind of new particle and we're very excited to 51 00:03:24,000 --> 00:03:25,960 Speaker 1: have you with us today, Katie, Thanks very much for 52 00:03:26,040 --> 00:03:28,920 Speaker 1: filling in for Jorge. We always love talking about the 53 00:03:29,000 --> 00:03:33,000 Speaker 1: biological side of physics with you, Yes, the the squashy 54 00:03:33,040 --> 00:03:36,080 Speaker 1: side of physics as I call it. And today we 55 00:03:36,120 --> 00:03:38,320 Speaker 1: are going to be talking about all the things that 56 00:03:38,400 --> 00:03:41,960 Speaker 1: we can see, because vision plays such an important role 57 00:03:42,160 --> 00:03:45,720 Speaker 1: in how we perceive the world and how we imagine it. 58 00:03:45,840 --> 00:03:47,680 Speaker 1: I think if you close your eyes and try to 59 00:03:47,760 --> 00:03:51,560 Speaker 1: imagine the room around you, probably the image in your 60 00:03:51,600 --> 00:03:54,720 Speaker 1: mind would be an image. It would be something built 61 00:03:54,760 --> 00:03:58,040 Speaker 1: out of your visual perception of the world around you. 62 00:03:58,160 --> 00:04:00,720 Speaker 1: That might be different, of course for blind listeners or 63 00:04:00,760 --> 00:04:03,520 Speaker 1: other people who don't have strong vision. There's also people 64 00:04:03,600 --> 00:04:08,320 Speaker 1: with a fantasia who can see, but they actually don't 65 00:04:08,400 --> 00:04:12,120 Speaker 1: think in pictures, they don't imagine pictures. That blows my 66 00:04:12,160 --> 00:04:14,480 Speaker 1: mind that you can see things but that you can't 67 00:04:14,520 --> 00:04:17,360 Speaker 1: have images in your head. Yeah, there's just so many 68 00:04:17,400 --> 00:04:21,560 Speaker 1: different types of ways that humans can perceive the world exactly, 69 00:04:21,600 --> 00:04:23,200 Speaker 1: and that means that there are so many layers to 70 00:04:23,240 --> 00:04:26,640 Speaker 1: these kinds of questions, like what is happening at which stage, 71 00:04:26,760 --> 00:04:28,520 Speaker 1: How is your eyeball seeing a photon, how is it 72 00:04:28,600 --> 00:04:31,000 Speaker 1: sending a message, how is that message interpreted, how is 73 00:04:31,040 --> 00:04:34,560 Speaker 1: that message experienced by your brain? How is that used 74 00:04:34,600 --> 00:04:37,080 Speaker 1: to make decisions and think about the world. But it's 75 00:04:37,080 --> 00:04:40,359 Speaker 1: clear that eyeballs are an important part of understanding the 76 00:04:40,400 --> 00:04:42,680 Speaker 1: world around us, and not just the eyeballs that we 77 00:04:42,760 --> 00:04:45,560 Speaker 1: have in our skulls, but the other kinds of eyeballs 78 00:04:45,560 --> 00:04:48,000 Speaker 1: that we build to look at the universe. Our X 79 00:04:48,120 --> 00:04:51,800 Speaker 1: ray telescopes and are infrared telescopes and our gamma ray 80 00:04:51,800 --> 00:04:54,279 Speaker 1: telescopes that can see photons that are well out of 81 00:04:54,320 --> 00:04:57,800 Speaker 1: our visual spectrum, and so understanding how photons work and 82 00:04:57,839 --> 00:05:01,360 Speaker 1: how we see them is pretty core to understanding the universe. 83 00:05:01,560 --> 00:05:03,919 Speaker 1: See not just with the eyes and our schools, but 84 00:05:04,000 --> 00:05:06,600 Speaker 1: the eyes in our hearts, and also the eyes attached 85 00:05:06,640 --> 00:05:10,280 Speaker 1: to a giant telescope. It would be really weird if 86 00:05:10,279 --> 00:05:12,400 Speaker 1: we built the telescope that was literally made out of 87 00:05:12,480 --> 00:05:17,960 Speaker 1: human eyeballs, like strung together. That sounds pretty That's a 88 00:05:18,000 --> 00:05:22,800 Speaker 1: real biology physics collaboration right there. But the eyeball does 89 00:05:22,880 --> 00:05:25,440 Speaker 1: touch on a lot of deep questions. There are questions 90 00:05:25,480 --> 00:05:27,680 Speaker 1: their philosophy, there are questions of biology, and there are 91 00:05:27,680 --> 00:05:31,440 Speaker 1: also questions of quantum physics. And so today on the podcast, 92 00:05:31,520 --> 00:05:34,440 Speaker 1: we're going to be peering into all of these questions 93 00:05:34,720 --> 00:05:44,520 Speaker 1: and asking can the human eye see a single photon? 94 00:05:44,920 --> 00:05:46,920 Speaker 1: So what do you think, Katie? Is the human eyeball 95 00:05:47,040 --> 00:05:52,240 Speaker 1: a quantum device? I mean, this is a really interesting question, 96 00:05:52,279 --> 00:05:56,039 Speaker 1: and I really love how people are kind of thinking 97 00:05:56,080 --> 00:05:59,359 Speaker 1: about this in terms of like, well, it seems really 98 00:05:59,400 --> 00:06:01,880 Speaker 1: tiny and you need to magnify it when you need 99 00:06:01,920 --> 00:06:05,520 Speaker 1: to make it bigger? How can you see one wavelength? 100 00:06:06,040 --> 00:06:10,440 Speaker 1: And when you think about the eyeball, it certainly seems 101 00:06:10,520 --> 00:06:13,480 Speaker 1: like the eye is too big right to see just 102 00:06:13,560 --> 00:06:16,960 Speaker 1: a little tiny particle. But I think when you examine 103 00:06:17,000 --> 00:06:20,200 Speaker 1: inside the eye and see how teeny tiny and delicate 104 00:06:20,400 --> 00:06:23,760 Speaker 1: some of these cells that actually allow us to see, 105 00:06:24,160 --> 00:06:27,320 Speaker 1: makes me a little more convinced that maybe we could 106 00:06:27,440 --> 00:06:30,920 Speaker 1: see something even as small as a single photon. Yeah. 107 00:06:30,920 --> 00:06:34,200 Speaker 1: I think when people think about quantum mechanics, they think physics, 108 00:06:34,240 --> 00:06:37,680 Speaker 1: and then they think about mechanical devices that humans have built, 109 00:06:37,800 --> 00:06:41,720 Speaker 1: optics and semiconductors and specialized materials, things that you don't 110 00:06:41,720 --> 00:06:45,200 Speaker 1: typically associate with biology. But of course our bodies are 111 00:06:45,240 --> 00:06:48,640 Speaker 1: built out of molecules and atoms, the same building blocks 112 00:06:48,720 --> 00:06:51,839 Speaker 1: as what's in that crazy quantum lab in the basement 113 00:06:51,880 --> 00:06:54,600 Speaker 1: of your building. And so in principle, it's possible for 114 00:06:54,680 --> 00:06:58,640 Speaker 1: the human body or anybody to have quantum effects. And 115 00:06:58,680 --> 00:07:00,960 Speaker 1: I think there's a whole burgeoning field now of people 116 00:07:00,960 --> 00:07:05,440 Speaker 1: studying quantum biology, things that happen in bodies that rely 117 00:07:05,880 --> 00:07:09,279 Speaker 1: on quantum mechanics. And so, in principle, as you say, 118 00:07:09,279 --> 00:07:12,800 Speaker 1: it's possible for biological cells to develop capabilities which rely 119 00:07:12,960 --> 00:07:16,680 Speaker 1: fundamentally on quantum mechanics, I mean the fact that we 120 00:07:16,920 --> 00:07:20,600 Speaker 1: can step outside and get burned by u V rays 121 00:07:20,760 --> 00:07:23,640 Speaker 1: from the sun is pretty compelling evidence to me of 122 00:07:23,680 --> 00:07:28,200 Speaker 1: the direct impact of physics, even at the very small scale, 123 00:07:28,480 --> 00:07:33,680 Speaker 1: on our bodies. And I deal with that all the time, exactly. 124 00:07:33,720 --> 00:07:36,520 Speaker 1: And so I went outside and walked around the campus 125 00:07:36,520 --> 00:07:39,280 Speaker 1: of UC Irvine and asked a bunch of random students, 126 00:07:39,280 --> 00:07:43,080 Speaker 1: I Ranto and one chemistry professor if they thought that 127 00:07:43,160 --> 00:07:46,600 Speaker 1: the human eye could see a single photon. That is, 128 00:07:46,640 --> 00:07:49,160 Speaker 1: if you were in a dark room and I shot 129 00:07:49,280 --> 00:07:52,960 Speaker 1: one photon at your eyeball, would you see a flash 130 00:07:53,000 --> 00:07:55,200 Speaker 1: of light or not? To think about it for a 131 00:07:55,240 --> 00:07:57,640 Speaker 1: minute before you hear these answers, do you think the 132 00:07:57,720 --> 00:08:00,840 Speaker 1: human eye could see a single photon? Years what folks 133 00:08:00,840 --> 00:08:03,200 Speaker 1: on the U c Irvine campus had to say, there's 134 00:08:03,200 --> 00:08:06,880 Speaker 1: a neurological sense and also a physical sense. I mean, 135 00:08:06,960 --> 00:08:10,520 Speaker 1: if physical sense doesn't happen, then you will neuroinologically you 136 00:08:10,560 --> 00:08:13,000 Speaker 1: cannot sense it. So it's like I think it's physically 137 00:08:13,040 --> 00:08:17,040 Speaker 1: it makes sense then yeah, I mean and fultonic absorbing 138 00:08:17,120 --> 00:08:21,000 Speaker 1: content in the content sense. I think a single is possible. 139 00:08:21,040 --> 00:08:23,640 Speaker 1: I just don't know the threshold. I don't think so. No, 140 00:08:23,720 --> 00:08:26,760 Speaker 1: I don't think so. Why not? Uh, probably because it's 141 00:08:26,760 --> 00:08:30,520 Speaker 1: too small. I don't think so, just because this is 142 00:08:30,560 --> 00:08:33,400 Speaker 1: the size of it, Like even the human eye it's 143 00:08:33,480 --> 00:08:36,200 Speaker 1: only capable of seeing so much, so we even need 144 00:08:36,240 --> 00:08:39,040 Speaker 1: to magnify it or make it a little larger. No, 145 00:08:39,120 --> 00:08:42,120 Speaker 1: I don't think so. Why not? Just I just think 146 00:08:42,160 --> 00:08:45,439 Speaker 1: it's too minute for the eye to like distinguished. Yes, 147 00:08:47,960 --> 00:08:51,000 Speaker 1: I'm just guessing. Honestly. I feel like it's you can't 148 00:08:51,000 --> 00:08:55,240 Speaker 1: see one single wavelength? Right, So how many photons do 149 00:08:55,240 --> 00:08:58,680 Speaker 1: you think it takes before your eyeball response. I don't 150 00:08:58,679 --> 00:09:00,880 Speaker 1: know if it's like an amount of photons. Maybe it's 151 00:09:00,880 --> 00:09:05,080 Speaker 1: like a unit of energy one probably not. Isn't light 152 00:09:05,160 --> 00:09:07,520 Speaker 1: just photons? So, yes, you can see it. Do you 153 00:09:07,559 --> 00:09:12,120 Speaker 1: think you could see a single a single one? No? No, no, 154 00:09:12,120 --> 00:09:15,440 Speaker 1: why not? Um, I'm not sure. I don't feel like 155 00:09:15,679 --> 00:09:17,920 Speaker 1: you could see it. Well, I don't know if my 156 00:09:18,000 --> 00:09:20,400 Speaker 1: brain could register it, but I feel like a rotter 157 00:09:20,520 --> 00:09:23,040 Speaker 1: cone gonna pick it up. But it might just like 158 00:09:23,120 --> 00:09:25,640 Speaker 1: consider it some kind of like random you know, burst 159 00:09:25,679 --> 00:09:29,000 Speaker 1: of something or some some miss neural mis spider or something. 160 00:09:29,360 --> 00:09:31,959 Speaker 1: So there's a lot of nose there. What do you think, Katie? 161 00:09:32,160 --> 00:09:37,319 Speaker 1: I understand the skepticism because it really does seem like 162 00:09:37,360 --> 00:09:41,520 Speaker 1: that would be too small of a stimulus too for 163 00:09:41,600 --> 00:09:43,920 Speaker 1: us to really pick up on. Why would we need 164 00:09:44,120 --> 00:09:47,800 Speaker 1: to see a single photon? Humans aren't necessarily known for 165 00:09:48,000 --> 00:09:51,960 Speaker 1: being the most sensitive of animals. Not to be mean 166 00:09:52,000 --> 00:09:54,480 Speaker 1: about it, but we we don't have the best sense 167 00:09:54,520 --> 00:09:57,440 Speaker 1: of smell, We don't certainly don't have the best sense 168 00:09:57,480 --> 00:10:00,760 Speaker 1: of vision or the best hearing, So why would we 169 00:10:00,840 --> 00:10:05,480 Speaker 1: be able to see a single photon? And I really 170 00:10:05,559 --> 00:10:09,600 Speaker 1: like people kind of questioning whether, even if we could 171 00:10:09,760 --> 00:10:12,600 Speaker 1: pick it up at the cellular level, whether the brain 172 00:10:12,679 --> 00:10:16,640 Speaker 1: could even process that. So I under understand the skepticism, 173 00:10:16,720 --> 00:10:20,840 Speaker 1: but I do I think that the fact that the 174 00:10:20,840 --> 00:10:27,959 Speaker 1: inner workings of the eyeball are so incredibly small and precise, 175 00:10:29,280 --> 00:10:32,280 Speaker 1: I'm somewhat leaning towards yes, we might be able to 176 00:10:32,280 --> 00:10:35,920 Speaker 1: see a single photon. Yeah, I was a little disappointed 177 00:10:35,960 --> 00:10:38,880 Speaker 1: that these folks didn't have more confidence in our eyeballs. 178 00:10:38,920 --> 00:10:41,320 Speaker 1: Though I think you're right, I don't understand why we 179 00:10:41,320 --> 00:10:43,760 Speaker 1: would need to be sensitive to a single photon. It's 180 00:10:43,800 --> 00:10:46,720 Speaker 1: not like we typically go hunting in the dark for rodents, right, 181 00:10:46,840 --> 00:10:48,880 Speaker 1: Like if an owl could see a single photon or 182 00:10:48,920 --> 00:10:51,520 Speaker 1: an eagle could see a single photon, I get it, 183 00:10:51,720 --> 00:10:54,439 Speaker 1: but human like, we're pretty much napping at night anyway. 184 00:10:54,520 --> 00:10:57,560 Speaker 1: I was interested in learning more about the fundamental science 185 00:10:57,559 --> 00:11:00,520 Speaker 1: at the heart of this process, where photons are sorbed 186 00:11:00,760 --> 00:11:03,720 Speaker 1: by cells in your eye and converted into signals. So 187 00:11:03,760 --> 00:11:05,719 Speaker 1: I reached out to an expert we have here at 188 00:11:05,760 --> 00:11:09,280 Speaker 1: You See Irvine. Rachel Martin is a professor of chemistry 189 00:11:09,320 --> 00:11:11,600 Speaker 1: and she studies of vision, and I asked her to 190 00:11:11,600 --> 00:11:14,680 Speaker 1: share some thoughts with us about why vision is cool. 191 00:11:15,400 --> 00:11:17,920 Speaker 1: I'm Rachel Martin, and I'm a professor of chemistry and 192 00:11:17,960 --> 00:11:21,240 Speaker 1: molecular biology and biochemistry at you See Irvine. Great, and 193 00:11:21,559 --> 00:11:24,079 Speaker 1: I understand that one of the focuses of your research 194 00:11:24,360 --> 00:11:26,720 Speaker 1: is vision in the eye. So tell me what do 195 00:11:26,760 --> 00:11:29,440 Speaker 1: you love about eyeballs? Wind about your career to the 196 00:11:29,440 --> 00:11:34,400 Speaker 1: study of vision. What entrances you about vision? Vision is amazing. 197 00:11:34,440 --> 00:11:38,080 Speaker 1: I mean, for one thing, um, humans are very visual animals. 198 00:11:38,120 --> 00:11:41,840 Speaker 1: This is mostly how we perceive our world. It's you know, 199 00:11:42,200 --> 00:11:45,280 Speaker 1: it's one of the most important senses for us, which 200 00:11:45,320 --> 00:11:46,800 Speaker 1: is not true for a lot of mammals. A lot 201 00:11:46,840 --> 00:11:50,199 Speaker 1: of mammals experienced the world through smell, but for us 202 00:11:50,240 --> 00:11:53,680 Speaker 1: it's really a lot of it is about seeing things 203 00:11:53,720 --> 00:11:57,320 Speaker 1: and that's that's kind of our main detection system for 204 00:11:57,360 --> 00:11:59,480 Speaker 1: the world. And I think that's really neat. And I 205 00:11:59,559 --> 00:12:03,120 Speaker 1: also think it's pretty amazing that vision works at all. 206 00:12:03,240 --> 00:12:06,040 Speaker 1: There are a lot of kind of happy accidents of 207 00:12:06,400 --> 00:12:08,360 Speaker 1: physics that have to be the way they are to 208 00:12:08,520 --> 00:12:11,280 Speaker 1: enable vision. I mean, so, for instance, the human visual 209 00:12:11,400 --> 00:12:15,679 Speaker 1: range overlaps almost exactly with um the kind of the 210 00:12:15,720 --> 00:12:18,960 Speaker 1: whole in the absorption spectrum of water. So you know, 211 00:12:19,000 --> 00:12:21,760 Speaker 1: water absorbs at a lot of frequencies, but there's just 212 00:12:21,800 --> 00:12:25,680 Speaker 1: this tiny little window that where it doesn't, and that's 213 00:12:25,720 --> 00:12:29,240 Speaker 1: where we're we're able to see. And I think that's 214 00:12:29,240 --> 00:12:33,080 Speaker 1: really neat all. Right, So Rachel is clearly very excited 215 00:12:33,120 --> 00:12:36,640 Speaker 1: about the eyeball. She has devoted her entire research career 216 00:12:36,800 --> 00:12:40,040 Speaker 1: to studying the human eye. And I love that about 217 00:12:40,080 --> 00:12:43,320 Speaker 1: science that every time we're making progress, it's because one 218 00:12:43,360 --> 00:12:46,800 Speaker 1: person has decided this is the most important question in 219 00:12:46,840 --> 00:12:49,480 Speaker 1: the universe, and I'm going to devote my entire research 220 00:12:49,520 --> 00:12:53,280 Speaker 1: career to studying the lens in the human eyeball. I 221 00:12:53,360 --> 00:12:58,240 Speaker 1: love it. I mean, the eyeball is so bizarre that 222 00:12:58,320 --> 00:13:02,680 Speaker 1: it even works. It has caused things like people to 223 00:13:02,760 --> 00:13:06,440 Speaker 1: be skeptical of evolution, thinking, well, the I is such 224 00:13:06,480 --> 00:13:11,439 Speaker 1: a complex device, how could it possibly naturally evolve? Which 225 00:13:11,480 --> 00:13:14,120 Speaker 1: I'm sure we're going to talk about. But I am 226 00:13:14,160 --> 00:13:18,840 Speaker 1: not surprised by the fascination with eyeballs because they're so 227 00:13:19,160 --> 00:13:22,440 Speaker 1: clever and how they work and it is not straightforward 228 00:13:22,480 --> 00:13:24,880 Speaker 1: at all. I totally agree. And so let's dig into 229 00:13:24,920 --> 00:13:27,720 Speaker 1: it a little bit. Since you're the biologist of the 230 00:13:27,760 --> 00:13:29,600 Speaker 1: pair of us, why don't you give us a rundown 231 00:13:29,760 --> 00:13:32,720 Speaker 1: on how the eye works? What are the essential elements 232 00:13:32,760 --> 00:13:35,240 Speaker 1: of it? What comes into play when you are seeing 233 00:13:35,360 --> 00:13:39,120 Speaker 1: a photon? Right? I mean the ie weirdly enough, is 234 00:13:39,160 --> 00:13:43,679 Speaker 1: basically like a little camera. So if you've ever played 235 00:13:43,800 --> 00:13:47,440 Speaker 1: with like a big lens or magnifying glass or something, 236 00:13:47,480 --> 00:13:50,400 Speaker 1: you know how you can like focus the sun's light 237 00:13:50,480 --> 00:13:53,000 Speaker 1: into a little dot burned some ants with it if 238 00:13:53,000 --> 00:13:56,959 Speaker 1: you're evil. So the eye actually has lenses in it 239 00:13:57,120 --> 00:14:01,679 Speaker 1: that can have like come in, refracts and focuses on 240 00:14:01,920 --> 00:14:06,360 Speaker 1: a spot. So first, outside of your eye, uh, you 241 00:14:06,480 --> 00:14:10,360 Speaker 1: have the cornea, So that's the thing that you may 242 00:14:10,559 --> 00:14:13,880 Speaker 1: directly place the contact lens on, or if you're unlucky, 243 00:14:13,920 --> 00:14:16,400 Speaker 1: you can scratch the corny and that's really bad. But 244 00:14:16,559 --> 00:14:21,440 Speaker 1: that's basically this uh it's a convex shape and so 245 00:14:22,440 --> 00:14:26,200 Speaker 1: light comes in and the light is refracted in this 246 00:14:26,400 --> 00:14:32,560 Speaker 1: cornya and then uh it goes through the pupil and 247 00:14:32,640 --> 00:14:37,480 Speaker 1: the iris can constrict or expand, allowing more or less 248 00:14:37,600 --> 00:14:41,200 Speaker 1: light in and just like the aperture of a camera. 249 00:14:41,680 --> 00:14:46,200 Speaker 1: And after that, you actually have the lens, which is 250 00:14:46,240 --> 00:14:49,600 Speaker 1: like the focus on the camera. It you have these 251 00:14:49,640 --> 00:14:52,360 Speaker 1: two little muscles that attached to the lynching can like 252 00:14:52,520 --> 00:14:56,479 Speaker 1: pull it or kind of relax and let it contract, 253 00:14:57,040 --> 00:15:00,360 Speaker 1: and that allows you to focus the light. So if 254 00:15:00,400 --> 00:15:03,440 Speaker 1: you've ever tried to focus on something and then you could, 255 00:15:03,480 --> 00:15:05,800 Speaker 1: it's blurry it first and then it comes into focus. 256 00:15:05,880 --> 00:15:10,480 Speaker 1: That's your lens actually squashing and stretching in order for 257 00:15:10,520 --> 00:15:12,880 Speaker 1: you to focus on something, and that will focus the 258 00:15:12,960 --> 00:15:16,880 Speaker 1: light onto the retina, so that is the back of 259 00:15:16,920 --> 00:15:22,440 Speaker 1: your eye. And on the retina are these uh photosensitive receptors. 260 00:15:22,480 --> 00:15:27,200 Speaker 1: So there are rods and cones. There are three kinds 261 00:15:27,200 --> 00:15:31,000 Speaker 1: of cones and only one type of rod. And it 262 00:15:31,160 --> 00:15:34,320 Speaker 1: is through the way that these rods and cones detect 263 00:15:34,480 --> 00:15:38,360 Speaker 1: this light that you can see everything from colors to 264 00:15:38,640 --> 00:15:43,520 Speaker 1: shapes two distances. It's really incredible. And then where we 265 00:15:43,560 --> 00:15:45,800 Speaker 1: haven't even talked about how it gets to the brain. 266 00:15:46,680 --> 00:15:51,040 Speaker 1: You have a bundle of nerves. Basically you do you 267 00:15:51,080 --> 00:15:55,400 Speaker 1: do good cable management, Daniel, Uh, My cable management is 268 00:15:55,400 --> 00:16:00,000 Speaker 1: a disaster. Actually, yeah, I'm no one to preach about 269 00:16:00,120 --> 00:16:04,160 Speaker 1: cable management. But our eyes bundle all of these basically 270 00:16:04,240 --> 00:16:08,600 Speaker 1: cables that run to all of these photo sensitive cells 271 00:16:08,880 --> 00:16:12,440 Speaker 1: and then into the optic nerve at the back of 272 00:16:12,480 --> 00:16:15,280 Speaker 1: the eye. It actually creates a blind spot in eye 273 00:16:15,400 --> 00:16:20,440 Speaker 1: because there's this cluster of of nerves that can't perceive 274 00:16:21,000 --> 00:16:24,440 Speaker 1: any light, but they're just transmitting the signals from these 275 00:16:24,440 --> 00:16:27,360 Speaker 1: cells and that runs all the way back to the 276 00:16:27,400 --> 00:16:31,960 Speaker 1: back of our brain and the occipital lobe. So it 277 00:16:32,040 --> 00:16:35,280 Speaker 1: is not it is not a straightforward system, but it 278 00:16:35,320 --> 00:16:38,120 Speaker 1: works really well. It's really amazing. I like the way 279 00:16:38,160 --> 00:16:40,720 Speaker 1: you've in an analogy to a camera. Um, so we 280 00:16:40,800 --> 00:16:43,800 Speaker 1: have just to review the cornea bend the light onto 281 00:16:43,840 --> 00:16:47,480 Speaker 1: the lens. The iris decides how much light goes into 282 00:16:47,520 --> 00:16:50,520 Speaker 1: the eye. The lens itself focuses light on the retina 283 00:16:50,560 --> 00:16:52,840 Speaker 1: and the retina sort of like the film or the 284 00:16:52,880 --> 00:16:56,160 Speaker 1: digital sensors that formed the image. And then translates it 285 00:16:56,200 --> 00:16:59,000 Speaker 1: into these neurological signals, and that's stuff to me is 286 00:16:59,000 --> 00:17:02,720 Speaker 1: super fascinating because the thing that you observe, the thing 287 00:17:02,720 --> 00:17:06,640 Speaker 1: that you experience, are just the messages along the nerve itself, 288 00:17:06,760 --> 00:17:10,560 Speaker 1: right your brain, your subjective experience. You don't observe the 289 00:17:10,600 --> 00:17:13,440 Speaker 1: photons themselves. You just get these messages in your brain 290 00:17:13,560 --> 00:17:16,160 Speaker 1: plays that in your head sort of as an experience 291 00:17:16,160 --> 00:17:18,200 Speaker 1: of color. But we'll dig into that in a minute. 292 00:17:18,200 --> 00:17:20,679 Speaker 1: I think that's really interesting and it's fascinating to me 293 00:17:20,800 --> 00:17:23,760 Speaker 1: that the way we constructed a camera is so similar 294 00:17:23,800 --> 00:17:26,000 Speaker 1: to the way the eyeball worked. Do you think that 295 00:17:26,040 --> 00:17:28,840 Speaker 1: we like stole, we cribbed from the eyeball, We're like, 296 00:17:29,119 --> 00:17:31,120 Speaker 1: this is a good design, let's do it like that. 297 00:17:31,320 --> 00:17:33,280 Speaker 1: Or do you think it's an example of like convergent 298 00:17:33,440 --> 00:17:36,760 Speaker 1: evolution of technology and biology. You know, that's a really 299 00:17:36,760 --> 00:17:40,359 Speaker 1: good question. I don't know, but I could believe either, 300 00:17:40,520 --> 00:17:44,879 Speaker 1: because we have been studying the eye for for many years, 301 00:17:44,960 --> 00:17:49,919 Speaker 1: even long before our sort of modern understanding of biology. 302 00:17:50,000 --> 00:17:53,720 Speaker 1: So I could definitely see there being some inspiration from 303 00:17:53,760 --> 00:17:57,359 Speaker 1: the eye. But it could also have just been from coincidence, 304 00:17:57,520 --> 00:18:01,480 Speaker 1: because you know, the very earliest camera, the camera obscure 305 00:18:01,560 --> 00:18:04,680 Speaker 1: where it's just basically a little pinhole where light comes in. 306 00:18:04,960 --> 00:18:08,359 Speaker 1: It's such a small pinhole, you have this refraction of 307 00:18:08,480 --> 00:18:11,200 Speaker 1: light that turns up an image that's upside down in 308 00:18:11,240 --> 00:18:14,160 Speaker 1: the wall behind it. I could see that having been 309 00:18:14,280 --> 00:18:17,960 Speaker 1: just discovered kind of by by coincidence or accident. And 310 00:18:18,000 --> 00:18:22,159 Speaker 1: then we essentially reverse engineered the eyeball only in a 311 00:18:22,240 --> 00:18:26,480 Speaker 1: mechanical sense. And again what's really cool is that with 312 00:18:26,600 --> 00:18:29,639 Speaker 1: the camera's the same thing. The image is upside down 313 00:18:29,760 --> 00:18:31,840 Speaker 1: in the camera, it's the same way, and that I 314 00:18:32,119 --> 00:18:36,800 Speaker 1: actually the image as it's projected onto the retina, that 315 00:18:37,040 --> 00:18:40,680 Speaker 1: area where all of the photoreceptors are is upside down 316 00:18:40,840 --> 00:18:44,240 Speaker 1: and it flips because our brain is able to flip 317 00:18:44,280 --> 00:18:47,760 Speaker 1: that image right side up. So there's so many middlemen 318 00:18:47,920 --> 00:18:51,280 Speaker 1: happening in our brain to interpret what we're seeing. You 319 00:18:51,359 --> 00:18:56,600 Speaker 1: can't always trust your eyes to be exact reporters of reality. 320 00:18:56,800 --> 00:19:00,000 Speaker 1: And there's another layer of similarity there because the evolution 321 00:19:00,240 --> 00:19:02,320 Speaker 1: of the technology of the camera, as you say, we 322 00:19:02,400 --> 00:19:05,280 Speaker 1: started with pinhole cameras and then we've got fancy lenses 323 00:19:05,400 --> 00:19:08,760 Speaker 1: also mirrors, doesn't it the evolution of the eyeball in 324 00:19:08,920 --> 00:19:12,760 Speaker 1: biology right, like we think that early eyes actually were 325 00:19:12,840 --> 00:19:15,880 Speaker 1: more like pinhole cameras. Can you take us through roughly, 326 00:19:15,960 --> 00:19:18,719 Speaker 1: like how do the human eye evolved? Because this is 327 00:19:18,840 --> 00:19:21,840 Speaker 1: an argument some creation is to use sometime to say 328 00:19:21,880 --> 00:19:25,119 Speaker 1: that evolution can possibly be reality, because how could you 329 00:19:25,200 --> 00:19:27,520 Speaker 1: evolve the eyeball? Can you take us through sort of 330 00:19:27,600 --> 00:19:30,440 Speaker 1: the rough picture of how the eyeball evolved? Yeah, So, 331 00:19:30,680 --> 00:19:32,719 Speaker 1: first of all, it's funny to me about people who 332 00:19:33,040 --> 00:19:35,920 Speaker 1: are so skeptical of the eyeball being able to evolve. 333 00:19:36,040 --> 00:19:40,000 Speaker 1: It's like, not only has it evolved, it's evolved multiple times. 334 00:19:40,040 --> 00:19:47,600 Speaker 1: So um, actually, cephalopods including octopuses, completely independently evolved their 335 00:19:47,720 --> 00:19:51,560 Speaker 1: eye from almost every other animal on the planet. And 336 00:19:51,640 --> 00:19:55,600 Speaker 1: so this is not just some kind of ridiculous look. 337 00:19:55,920 --> 00:19:59,200 Speaker 1: It does make it seem a little bit more inevitable. 338 00:19:59,320 --> 00:20:02,879 Speaker 1: So when we were basically flat worms, we would have 339 00:20:03,680 --> 00:20:09,240 Speaker 1: kind of just like, uh, some cluster of photosensitive cells 340 00:20:09,359 --> 00:20:13,000 Speaker 1: that could detect light or dark, not really images, just 341 00:20:13,080 --> 00:20:16,040 Speaker 1: kind of like hey that's light, I go towards it, 342 00:20:16,160 --> 00:20:19,560 Speaker 1: or this is dark, I go towards it. So at 343 00:20:19,640 --> 00:20:23,760 Speaker 1: this very basic level, something like a flat worm and 344 00:20:23,920 --> 00:20:28,560 Speaker 1: the you know, very early ocean could go up towards 345 00:20:28,800 --> 00:20:32,159 Speaker 1: the sunlight, or recede back down into the darkness, or 346 00:20:32,200 --> 00:20:36,120 Speaker 1: go towards a spot obscured by the sunlight, maybe some 347 00:20:36,119 --> 00:20:38,760 Speaker 1: something to eat or something. But it couldn't form like 348 00:20:38,800 --> 00:20:42,159 Speaker 1: an actual image. But already that's a huge step forward. 349 00:20:42,200 --> 00:20:46,560 Speaker 1: That's recognizing that the universe around you is filled with 350 00:20:46,760 --> 00:20:50,800 Speaker 1: useful information, information you were literally blind to before you 351 00:20:50,840 --> 00:20:53,560 Speaker 1: develop this capacity. And now that you can sense the 352 00:20:53,560 --> 00:20:55,439 Speaker 1: fact that there are a bunch of photons over here 353 00:20:55,480 --> 00:20:57,800 Speaker 1: and not a bunch of photons over there, easy, useful 354 00:20:58,200 --> 00:21:00,399 Speaker 1: always makes me fantasize that we might be able to 355 00:21:00,440 --> 00:21:02,879 Speaker 1: like develops some new kind of cell that's sensitive to 356 00:21:03,040 --> 00:21:06,000 Speaker 1: dark matter or neutrinos or something, you know, in the 357 00:21:06,160 --> 00:21:09,520 Speaker 1: form the basis of seeing the universe in another way, right, like, 358 00:21:09,600 --> 00:21:12,919 Speaker 1: because we've done that before, we've developed the capacity to 359 00:21:12,960 --> 00:21:16,760 Speaker 1: see a previously invisible part of the universe anyway. That 360 00:21:16,800 --> 00:21:19,880 Speaker 1: just gives me hope, you know, for future evolution if 361 00:21:19,920 --> 00:21:22,480 Speaker 1: we live a few more million years, I think it's 362 00:21:22,560 --> 00:21:25,520 Speaker 1: definitely possible. Al Right, So how do you go from 363 00:21:25,600 --> 00:21:28,760 Speaker 1: having cells that can sense the existence of light to 364 00:21:29,119 --> 00:21:33,000 Speaker 1: you know, forming images and watching TV shows? Well, first, 365 00:21:33,400 --> 00:21:38,359 Speaker 1: there's something important that's missing with just this cluster of photoreceptors. 366 00:21:38,400 --> 00:21:43,359 Speaker 1: It's that you don't necessarily understand what direction something is, 367 00:21:43,920 --> 00:21:46,720 Speaker 1: or what's up and what's down. And so if you 368 00:21:46,800 --> 00:21:51,640 Speaker 1: actually recede those cells into like a little cave, like 369 00:21:51,720 --> 00:21:55,320 Speaker 1: a little socket, it matters which way the light is shining, 370 00:21:55,400 --> 00:21:58,560 Speaker 1: because you've limited the entry point of the light, and 371 00:21:58,640 --> 00:22:02,399 Speaker 1: now your aim can tell whether the light is coming 372 00:22:02,440 --> 00:22:06,040 Speaker 1: from up or from down. And then from there, now 373 00:22:06,080 --> 00:22:11,400 Speaker 1: that you've got basically an empty eye socket with receptors 374 00:22:11,440 --> 00:22:13,960 Speaker 1: at the back of the socket, once you start to 375 00:22:14,080 --> 00:22:18,480 Speaker 1: close that opening to the socket, now you're getting that pinhole. 376 00:22:18,560 --> 00:22:22,280 Speaker 1: So we're getting to the camera obscure apart where you 377 00:22:22,920 --> 00:22:26,119 Speaker 1: will get this the light. Not only are you able 378 00:22:26,160 --> 00:22:29,159 Speaker 1: to better tell what direction the light is, not just 379 00:22:29,400 --> 00:22:32,320 Speaker 1: up and down, but maybe side to side three sixty 380 00:22:32,440 --> 00:22:35,800 Speaker 1: kind of understanding of where the lights coming from. You 381 00:22:35,960 --> 00:22:40,080 Speaker 1: could also start to form very simple images because now 382 00:22:40,119 --> 00:22:43,639 Speaker 1: you're able to actually bend the light such that it 383 00:22:44,080 --> 00:22:47,120 Speaker 1: can become refracted and hit the back of your eye 384 00:22:47,119 --> 00:22:50,679 Speaker 1: in this image. I think that's a little counterintuitive that 385 00:22:50,800 --> 00:22:54,440 Speaker 1: you go from here's a slab where I can see photons, 386 00:22:54,520 --> 00:22:57,520 Speaker 1: and the step forward is to hide that is, to 387 00:22:57,560 --> 00:23:00,480 Speaker 1: like bury that inside you so that it's only can 388 00:23:00,480 --> 00:23:03,040 Speaker 1: be hit by a few photons that happened to pass 389 00:23:03,080 --> 00:23:06,160 Speaker 1: through like a little hole you make. That's counterintuitive because 390 00:23:06,200 --> 00:23:08,720 Speaker 1: you're getting less information, it seems like, because you're getting 391 00:23:08,880 --> 00:23:12,200 Speaker 1: fewer photons, but you're right, it's more information because you're 392 00:23:12,200 --> 00:23:15,320 Speaker 1: restricting the photons. So now you can tell this photon 393 00:23:15,520 --> 00:23:17,960 Speaker 1: must have come from up or must have come from down, 394 00:23:18,160 --> 00:23:20,040 Speaker 1: and based on where it hits on the inside of 395 00:23:20,040 --> 00:23:22,320 Speaker 1: this cavity, as you say, you can form an image. 396 00:23:22,440 --> 00:23:24,280 Speaker 1: That's a pretty cool technology. I don't know if I 397 00:23:24,320 --> 00:23:26,520 Speaker 1: would have thought of that myself. I mean, that is 398 00:23:26,600 --> 00:23:29,600 Speaker 1: one of the fascinating things about the senses. So much 399 00:23:29,640 --> 00:23:34,560 Speaker 1: of it isn't just the ability to sense something, but 400 00:23:34,760 --> 00:23:39,800 Speaker 1: the ability to prune out information, to restrict the information 401 00:23:39,840 --> 00:23:43,600 Speaker 1: you're getting so that your brain can make sense of 402 00:23:44,000 --> 00:23:46,520 Speaker 1: what is happening. Because if you're just getting all the 403 00:23:46,560 --> 00:23:50,439 Speaker 1: information all the time, you can't differentiate it, and so 404 00:23:50,520 --> 00:23:54,040 Speaker 1: you're not actually going to form a clear picture of 405 00:23:54,080 --> 00:23:56,560 Speaker 1: what is happening around you. And I think you're right. 406 00:23:56,600 --> 00:23:59,520 Speaker 1: It's that differentiation that's key. If you're seeing photons on 407 00:23:59,520 --> 00:24:01,399 Speaker 1: one side of the cavity and not the other. The 408 00:24:01,440 --> 00:24:04,520 Speaker 1: relative intensity there is what is telling you this source 409 00:24:04,520 --> 00:24:06,919 Speaker 1: of light is only coming from that direction and not 410 00:24:07,080 --> 00:24:09,800 Speaker 1: from the other. So it's about like comparative processing of 411 00:24:09,800 --> 00:24:12,720 Speaker 1: those signals, not just are their photons or not, but 412 00:24:12,840 --> 00:24:14,920 Speaker 1: like looking at where you're getting the signals and where 413 00:24:14,960 --> 00:24:17,560 Speaker 1: you're not getting the signals and using that to form 414 00:24:17,640 --> 00:24:19,800 Speaker 1: like a mental model of what's going on out there 415 00:24:19,800 --> 00:24:23,359 Speaker 1: in the world. Right, And so as we're tracing this 416 00:24:23,440 --> 00:24:26,600 Speaker 1: evolution of the eye, now we've got this cave right, 417 00:24:26,760 --> 00:24:30,439 Speaker 1: this this eyeball shaped cave with this little pinhole now 418 00:24:30,680 --> 00:24:33,439 Speaker 1: allowing us to see better direction and maybe start to 419 00:24:33,480 --> 00:24:38,600 Speaker 1: form these very blurry images. And then you can seal 420 00:24:38,760 --> 00:24:44,800 Speaker 1: that off right to protect the photoreceptors. And however, you 421 00:24:44,920 --> 00:24:46,720 Speaker 1: need to make sure that that inside of the eye 422 00:24:46,800 --> 00:24:49,480 Speaker 1: is still fluid filled. We are remember at this point 423 00:24:49,520 --> 00:24:54,960 Speaker 1: we are marine animals, probably some kind of very early 424 00:24:55,240 --> 00:25:00,399 Speaker 1: predecessor to uh, some species of fish, and you can't 425 00:25:00,440 --> 00:25:03,800 Speaker 1: just have an air pocket as an As a fish, 426 00:25:04,000 --> 00:25:07,960 Speaker 1: you typically want to have your organs filled with fluid. 427 00:25:08,080 --> 00:25:10,720 Speaker 1: Since your eye has been evolving to be able to 428 00:25:11,680 --> 00:25:14,880 Speaker 1: refract light in water. If you have the sudden air 429 00:25:14,920 --> 00:25:17,719 Speaker 1: pocket that's not going to allow you to see, so 430 00:25:17,800 --> 00:25:21,880 Speaker 1: you actually have this fluid filled I now of this 431 00:25:22,200 --> 00:25:25,119 Speaker 1: vitreous humor, and we actually still have that in the 432 00:25:25,200 --> 00:25:29,080 Speaker 1: human eye. It is not just an empty balloon filled 433 00:25:29,080 --> 00:25:32,240 Speaker 1: with air. It is filled with fluid. And then all 434 00:25:32,280 --> 00:25:35,879 Speaker 1: you need to start to get to the eye of 435 00:25:35,920 --> 00:25:40,440 Speaker 1: a more complex animal that can see more detailed images 436 00:25:41,119 --> 00:25:46,360 Speaker 1: is a lens and a cornea. So once you've started 437 00:25:46,359 --> 00:25:48,200 Speaker 1: to get this lens in that corner, you're able to 438 00:25:48,200 --> 00:25:52,760 Speaker 1: actually focus and make these specific images. And then uh, 439 00:25:53,040 --> 00:25:56,560 Speaker 1: from there, you have so many possibilities opened up to you. 440 00:25:56,600 --> 00:25:59,959 Speaker 1: Even though animals since of vision, can be really different, 441 00:26:00,480 --> 00:26:04,320 Speaker 1: the thing that they all share is they're really useful, uh, 442 00:26:04,359 --> 00:26:08,119 Speaker 1: in terms of their specific evolutionary niche. It's amazing that 443 00:26:08,200 --> 00:26:10,600 Speaker 1: we can reconstruct this story and that along with this 444 00:26:10,680 --> 00:26:13,719 Speaker 1: story gives us a clue about our own history seeing 445 00:26:13,760 --> 00:26:16,400 Speaker 1: things underwater from our great great great great great great 446 00:26:16,400 --> 00:26:19,680 Speaker 1: great great great ancestors, and also helps explain why some 447 00:26:19,760 --> 00:26:22,600 Speaker 1: eyeballs are different from other eyeballs. Here's a nice little 448 00:26:22,600 --> 00:26:26,639 Speaker 1: story from Rachel Martin explaining why fish eyeballs look different 449 00:26:26,760 --> 00:26:30,520 Speaker 1: from ours. When a photon hits your eyeball. You know, 450 00:26:30,640 --> 00:26:33,720 Speaker 1: first it has to go through the cornea and the lens, 451 00:26:34,840 --> 00:26:37,359 Speaker 1: and those things are really important because that's where we 452 00:26:37,400 --> 00:26:41,040 Speaker 1: get a lot of the focusing power, and particularly in 453 00:26:41,280 --> 00:26:44,240 Speaker 1: terrestrial organisms, you know, a lot of the focusing power 454 00:26:44,280 --> 00:26:46,560 Speaker 1: of your eyelands actually comes from that air water interface 455 00:26:46,600 --> 00:26:49,399 Speaker 1: at the cornea. And it's something that we don't necessarily 456 00:26:49,400 --> 00:26:52,880 Speaker 1: think about. And I know when I was a little kid, 457 00:26:53,480 --> 00:26:56,520 Speaker 1: you know, I really liked swimming, and I was really 458 00:26:56,560 --> 00:26:59,760 Speaker 1: sure that if I practiced enough, I would be able 459 00:26:59,800 --> 00:27:03,359 Speaker 1: to see underwater without goggles. And so you know, I 460 00:27:03,359 --> 00:27:05,359 Speaker 1: would try and try and try, and I thought it 461 00:27:05,400 --> 00:27:07,520 Speaker 1: was just you know, I have to keep trying and 462 00:27:07,640 --> 00:27:10,960 Speaker 1: keep practicing. But you know, my eyes are not optimized 463 00:27:11,000 --> 00:27:15,200 Speaker 1: to work underwater because I'm a terrestrial organism and so um. 464 00:27:15,240 --> 00:27:18,320 Speaker 1: You know, so no matter how much do you practice, 465 00:27:18,640 --> 00:27:21,920 Speaker 1: you need that air layer in front of your eye 466 00:27:21,960 --> 00:27:24,360 Speaker 1: for the you know, for the light to be properly 467 00:27:24,520 --> 00:27:27,199 Speaker 1: refracted to make an image. Our eyes are optimized that 468 00:27:27,240 --> 00:27:30,440 Speaker 1: way because you know, the lens is kind of flattened 469 00:27:30,920 --> 00:27:36,480 Speaker 1: and uh also, you know, the distribution of proteins structural 470 00:27:36,480 --> 00:27:39,320 Speaker 1: proteins inside the lens is optimized to work with that 471 00:27:39,400 --> 00:27:42,040 Speaker 1: air water interface at the cornea, whereas if you look 472 00:27:42,080 --> 00:27:47,280 Speaker 1: at a fish is lends, that's usually very spherical. And 473 00:27:47,440 --> 00:27:51,359 Speaker 1: that's because in a fish lens there's no air. Of course, 474 00:27:51,400 --> 00:27:53,480 Speaker 1: the fish is underwater, and so the proteins in that 475 00:27:53,600 --> 00:27:55,159 Speaker 1: lens have to do all the work. And this is 476 00:27:55,200 --> 00:27:58,360 Speaker 1: a really interesting thing too to notice. Next time you're 477 00:27:58,400 --> 00:28:01,879 Speaker 1: at like a public aquarium, you find the biggest fish 478 00:28:01,960 --> 00:28:04,159 Speaker 1: you can and look at their eyes, you can usually 479 00:28:04,160 --> 00:28:06,320 Speaker 1: see the lens. It's you know, it's often you know, 480 00:28:06,400 --> 00:28:09,439 Speaker 1: pretty easy to see in the fish eye, so you 481 00:28:09,440 --> 00:28:11,760 Speaker 1: can see the shapes. All right, So I think now 482 00:28:11,760 --> 00:28:13,879 Speaker 1: we have an understanding of what the eyeball is and 483 00:28:13,920 --> 00:28:16,679 Speaker 1: the basic mechanism and geometry of it. I want to 484 00:28:16,720 --> 00:28:19,960 Speaker 1: dig into the physics of color, what color means, and 485 00:28:20,000 --> 00:28:23,240 Speaker 1: how our eyeballs see these photons. But first let's take 486 00:28:23,440 --> 00:28:38,560 Speaker 1: a quick break. All right, we're back and we're talking 487 00:28:38,600 --> 00:28:42,280 Speaker 1: about eyeballs. We're not eating eyeballs. We're talking about shooting 488 00:28:42,320 --> 00:28:46,040 Speaker 1: photons into eyeballs and thinking about how they respond and 489 00:28:46,120 --> 00:28:48,960 Speaker 1: what that means and what your brain tells you about 490 00:28:49,000 --> 00:28:52,400 Speaker 1: the signals that crawl up the optic nerves O, Katie, 491 00:28:52,440 --> 00:28:55,080 Speaker 1: what color are you surrounded by right now? What color 492 00:28:55,080 --> 00:28:57,680 Speaker 1: are you looking at as we talk about this, I'm 493 00:28:57,720 --> 00:29:01,480 Speaker 1: actually looking at a very lovely shape of teal because 494 00:29:02,320 --> 00:29:08,360 Speaker 1: this apartment has painted in beautiful colors. Um the owner 495 00:29:08,400 --> 00:29:11,640 Speaker 1: of this apartment really loves teal, and so almost all 496 00:29:11,640 --> 00:29:14,160 Speaker 1: the walls are painted teal. It's it's very nice. I'm 497 00:29:14,200 --> 00:29:17,920 Speaker 1: not complaining. It's just you can really tell he loves 498 00:29:18,080 --> 00:29:22,239 Speaker 1: he loved teal, the guy who painted this apartment. My 499 00:29:22,320 --> 00:29:25,200 Speaker 1: daughter Hazel loves teal also, and she loves a very 500 00:29:25,200 --> 00:29:28,680 Speaker 1: particular shade of it. And for me, I'm like, well, 501 00:29:28,720 --> 00:29:30,520 Speaker 1: it's all just sort of this blue, and she's like, 502 00:29:30,520 --> 00:29:33,120 Speaker 1: oh my god, it's not just all blue, Like this 503 00:29:33,160 --> 00:29:35,360 Speaker 1: is blue and that's teal and this is something else 504 00:29:35,440 --> 00:29:42,000 Speaker 1: and monster. It's interesting to me that we do have 505 00:29:42,040 --> 00:29:45,040 Speaker 1: this very rich experience of color. You know that we 506 00:29:45,120 --> 00:29:48,280 Speaker 1: have a very different reaction to photons of one frequency 507 00:29:48,440 --> 00:29:50,560 Speaker 1: and another. So I think it's important that we dig 508 00:29:50,560 --> 00:29:53,080 Speaker 1: into what that means, what the physics is of it, 509 00:29:53,120 --> 00:29:55,160 Speaker 1: why it is that some photons give us a different 510 00:29:55,200 --> 00:29:58,200 Speaker 1: reaction from other colors. When I was a kid and 511 00:29:58,240 --> 00:30:01,760 Speaker 1: I learned there were only three to front wavelengths of white. 512 00:30:02,360 --> 00:30:05,120 Speaker 1: It was really bewildering because it's like, Okay, how do 513 00:30:05,240 --> 00:30:08,040 Speaker 1: we see so many different colors than if we there 514 00:30:08,040 --> 00:30:12,360 Speaker 1: are only these three wavelengths of why you would think 515 00:30:12,400 --> 00:30:16,480 Speaker 1: we would only see like red or green or blue. Yeah, 516 00:30:16,480 --> 00:30:19,040 Speaker 1: that's really interesting. And of course there are more than 517 00:30:19,080 --> 00:30:22,040 Speaker 1: just three wavelengths of light, all right, There are an 518 00:30:22,080 --> 00:30:25,840 Speaker 1: infinite number. So in the end, what is light? Light 519 00:30:25,880 --> 00:30:30,040 Speaker 1: are these little packets of energy, these photon, these quantized 520 00:30:30,120 --> 00:30:34,280 Speaker 1: little wiggles in the electromagnetic field. So the electromagnetic field 521 00:30:34,280 --> 00:30:37,280 Speaker 1: is something that fills all of space. The whole universe 522 00:30:37,400 --> 00:30:39,680 Speaker 1: has the field in it, and when there's energy in 523 00:30:39,720 --> 00:30:41,760 Speaker 1: the field, they can travel through that field. It consort 524 00:30:41,800 --> 00:30:45,080 Speaker 1: of like wiggle. Imagine like a guitar string and you're 525 00:30:45,080 --> 00:30:47,840 Speaker 1: sending a pulse along it. That's a photon. It's a 526 00:30:47,840 --> 00:30:50,920 Speaker 1: wiggle in the electromagnetic field. And it's a very special 527 00:30:51,000 --> 00:30:53,680 Speaker 1: kind of wiggle because it's self perpetuating. You know, it 528 00:30:53,720 --> 00:30:56,160 Speaker 1: can exist and then it can zoom across the universe 529 00:30:56,160 --> 00:30:59,080 Speaker 1: and exists somewhere else. It doesn't like the fuse or 530 00:30:59,120 --> 00:31:02,400 Speaker 1: spread out. It's like persistent and discreet, and that's in 531 00:31:02,440 --> 00:31:05,040 Speaker 1: the end, what we call a particle. All particles that 532 00:31:05,080 --> 00:31:07,800 Speaker 1: we see and experience in the universe are these little 533 00:31:07,840 --> 00:31:12,640 Speaker 1: discretized wiggles in quantum fields. Now people think about photons 534 00:31:12,760 --> 00:31:16,560 Speaker 1: as photons, as quantum particles, as discreet, and it's true 535 00:31:16,600 --> 00:31:18,960 Speaker 1: that they are quantized. Like you can have one photon 536 00:31:19,320 --> 00:31:22,880 Speaker 1: or two photons or seventy four photons. You can't have 537 00:31:23,040 --> 00:31:26,560 Speaker 1: one and a half photons or one point seven two photons. 538 00:31:26,880 --> 00:31:30,120 Speaker 1: You can only have integer numbers of photons. For those 539 00:31:30,120 --> 00:31:31,800 Speaker 1: of you curious about the physics of it and how 540 00:31:31,800 --> 00:31:34,320 Speaker 1: it is discovered, we have a whole podcast episode about 541 00:31:34,440 --> 00:31:38,080 Speaker 1: the photoelectric effect and how Einstein realized that photons came 542 00:31:38,120 --> 00:31:41,680 Speaker 1: in these little numbered packets. But there's another really important 543 00:31:41,680 --> 00:31:45,120 Speaker 1: fact about each photon, and that's its energy, and that's 544 00:31:45,120 --> 00:31:48,960 Speaker 1: something that is not quantized. So a single photon can 545 00:31:49,000 --> 00:31:53,480 Speaker 1: have any energy, meaning to have any wavelength. So typical 546 00:31:53,600 --> 00:31:56,240 Speaker 1: visible light is like four hundred to six hundred and 547 00:31:56,240 --> 00:31:59,960 Speaker 1: fifty nanometers, but there's an infinite number of different way 548 00:32:00,120 --> 00:32:03,080 Speaker 1: links between four hundred and six fifty. Just because of 549 00:32:03,120 --> 00:32:07,240 Speaker 1: photon is quantized doesn't mean it's energy levels are quantized. 550 00:32:07,400 --> 00:32:10,440 Speaker 1: So if there's an infinite number of frequencies. Would that 551 00:32:10,520 --> 00:32:13,520 Speaker 1: mean there are an infinite number of colors? Great question 552 00:32:13,560 --> 00:32:15,960 Speaker 1: and a really deep philosophy question, And the way I 553 00:32:16,000 --> 00:32:19,000 Speaker 1: think about it is that photons don't have colors. Color 554 00:32:19,120 --> 00:32:22,160 Speaker 1: is your brain's interpretation of the signals that it's getting. 555 00:32:22,200 --> 00:32:24,479 Speaker 1: There are an infinite number of different photons with an 556 00:32:24,480 --> 00:32:28,360 Speaker 1: infinite number of different frequencies, right, But those frequencies don't 557 00:32:28,360 --> 00:32:31,320 Speaker 1: necessarily all have a color assigned to them. The color 558 00:32:31,400 --> 00:32:34,280 Speaker 1: is something that your brain does, assigning it to the 559 00:32:34,320 --> 00:32:38,120 Speaker 1: response of the optical nerve. But in theory, if you 560 00:32:38,240 --> 00:32:43,000 Speaker 1: get enough living organisms that have some kind of eyeball 561 00:32:43,680 --> 00:32:47,000 Speaker 1: and some kind of brain that can detect some kind 562 00:32:47,040 --> 00:32:51,760 Speaker 1: of frequencies, we get enough, including all life on Earth 563 00:32:51,760 --> 00:32:55,360 Speaker 1: and probably a bunch of aliens, could we all perceive 564 00:32:56,040 --> 00:33:02,000 Speaker 1: infinite colors. It's a great question of neurology and philosophy 565 00:33:02,040 --> 00:33:05,000 Speaker 1: that I don't know the answer to, and you know, 566 00:33:05,080 --> 00:33:07,640 Speaker 1: we don't know the answer to even more basic questions 567 00:33:07,720 --> 00:33:10,840 Speaker 1: like is the red that you perceive the same read 568 00:33:10,920 --> 00:33:13,320 Speaker 1: as I perceive. It's a really old question that people 569 00:33:13,320 --> 00:33:16,640 Speaker 1: have been asking since they've been smoking bananappeals around the campfire, 570 00:33:16,800 --> 00:33:19,400 Speaker 1: and one that we still don't have an answer to. 571 00:33:19,720 --> 00:33:21,680 Speaker 1: And I think it's a great kind of question because 572 00:33:21,680 --> 00:33:25,680 Speaker 1: it shows us so the limitations of science. People think 573 00:33:25,680 --> 00:33:28,960 Speaker 1: about sciences maybe all powerful ways to reveal the nature 574 00:33:29,000 --> 00:33:32,040 Speaker 1: of the universe, and science is very powerful, but not 575 00:33:32,160 --> 00:33:36,600 Speaker 1: every question is necessarily a scientific question. You can't conduct 576 00:33:36,600 --> 00:33:39,320 Speaker 1: an experiment or come up with a theory that helps 577 00:33:39,360 --> 00:33:42,520 Speaker 1: you probe it, then science isn't necessarily the best tool. 578 00:33:42,960 --> 00:33:45,320 Speaker 1: And so the question of like is your red the 579 00:33:45,360 --> 00:33:49,720 Speaker 1: same as my red, relies purely on our subjective experiences, 580 00:33:49,760 --> 00:33:52,520 Speaker 1: which we can't translate from my brain to your brain, 581 00:33:52,640 --> 00:33:54,240 Speaker 1: so we have no way of knowing. I can't like, 582 00:33:54,600 --> 00:33:57,920 Speaker 1: measure the redness of your experience. So some of these 583 00:33:57,960 --> 00:34:00,760 Speaker 1: really deep and fascinating questions are for us treadingly just 584 00:34:00,800 --> 00:34:03,240 Speaker 1: past the fingertips of science. Well, I have a really 585 00:34:03,240 --> 00:34:05,880 Speaker 1: easy answer to that, and that my red is a 586 00:34:06,160 --> 00:34:11,480 Speaker 1: fire truck red. So question solved exactly when we point 587 00:34:11,480 --> 00:34:13,440 Speaker 1: to a fire truck and we say that's red. We 588 00:34:13,520 --> 00:34:16,200 Speaker 1: of course don't know what you're seeing and what I'm seeing. 589 00:34:16,239 --> 00:34:19,400 Speaker 1: If that actually looks like teal to my daughter, we'll see. 590 00:34:19,760 --> 00:34:22,280 Speaker 1: Let's go through a little bit the mechanism of how 591 00:34:22,320 --> 00:34:25,359 Speaker 1: your eye can tell which photons have hit it, like 592 00:34:25,440 --> 00:34:28,719 Speaker 1: which frequencies of light are hitting it. But before we 593 00:34:28,760 --> 00:34:31,400 Speaker 1: do that, let's just remind ourselves, like why are there 594 00:34:31,440 --> 00:34:34,239 Speaker 1: different frequencies? You know? Why is it that the fire 595 00:34:34,280 --> 00:34:37,880 Speaker 1: truck is red and blueberries are blue, and that leaves 596 00:34:37,880 --> 00:34:40,680 Speaker 1: are green and the sky is blue. Why are there 597 00:34:40,680 --> 00:34:43,520 Speaker 1: these different colors in our world? And the fundamental level 598 00:34:43,560 --> 00:34:47,600 Speaker 1: of reason from physics is to one is that sometimes 599 00:34:47,680 --> 00:34:51,920 Speaker 1: things get hot and hot things and glow at different temperatures. 600 00:34:51,960 --> 00:34:54,279 Speaker 1: Like the reason that we get light from the sun 601 00:34:54,400 --> 00:34:56,839 Speaker 1: is because the Sun is super duper hot, and as 602 00:34:56,880 --> 00:34:59,600 Speaker 1: things get hotter, they tend to emit light in higher 603 00:34:59,640 --> 00:35:03,200 Speaker 1: freak and see photons. So things that are cold in 604 00:35:03,320 --> 00:35:06,640 Speaker 1: midlight in the infrared, things that are warmer in mid 605 00:35:06,760 --> 00:35:09,200 Speaker 1: light in the visible like the sun. Things that are 606 00:35:09,239 --> 00:35:13,439 Speaker 1: super duper hot like accretion disks around black holes, emit 607 00:35:13,600 --> 00:35:16,239 Speaker 1: light in the ultraviolet or even up to the X 608 00:35:16,360 --> 00:35:19,480 Speaker 1: rays and gamma rays. These are all just different frequencies 609 00:35:19,520 --> 00:35:22,560 Speaker 1: along the electromagnetic spectrum. Is this is why when you 610 00:35:22,680 --> 00:35:26,680 Speaker 1: have a fire, you have sort of a really really 611 00:35:26,719 --> 00:35:29,960 Speaker 1: hot fire, it's going to be like white hot versus 612 00:35:30,080 --> 00:35:32,799 Speaker 1: orange hot. And blue hot exactly. And if you are 613 00:35:32,840 --> 00:35:36,000 Speaker 1: an amateur at home black smith, you know that white 614 00:35:36,000 --> 00:35:38,920 Speaker 1: hot and red hot are different temperatures of your steel. 615 00:35:38,960 --> 00:35:41,520 Speaker 1: That's something people have known for thousands of years before 616 00:35:41,520 --> 00:35:44,920 Speaker 1: we understood the physics involved. Right, that's like folk physics. 617 00:35:45,160 --> 00:35:47,680 Speaker 1: It's pretty cool. And the other way that color comes 618 00:35:47,680 --> 00:35:52,239 Speaker 1: into play physically isn't how materials absorb and reflect color. Like, 619 00:35:52,280 --> 00:35:55,000 Speaker 1: if you're looking at an object and it's red, it's 620 00:35:55,040 --> 00:35:58,560 Speaker 1: because you're getting red photons. You're getting photons of a 621 00:35:58,600 --> 00:36:01,120 Speaker 1: frequency that your brain is signed to. The color red 622 00:36:01,280 --> 00:36:04,399 Speaker 1: to your eyeball from that object, I say it's being 623 00:36:04,480 --> 00:36:07,440 Speaker 1: hit by white light. Light from the sun tends to 624 00:36:07,480 --> 00:36:10,120 Speaker 1: cover the whole visible spectrum. The reason you see it 625 00:36:10,160 --> 00:36:13,760 Speaker 1: is red is not because it's absorbing red. Right, doesn't 626 00:36:13,840 --> 00:36:16,800 Speaker 1: get red from the red photons. It's because it's absorbing 627 00:36:16,880 --> 00:36:20,280 Speaker 1: everything but red, and only the red light is getting 628 00:36:20,320 --> 00:36:23,279 Speaker 1: reflected to your eyeball. Right, A general thing with our 629 00:36:23,400 --> 00:36:28,120 Speaker 1: senses is anything you sense, from hearing to vision has 630 00:36:28,160 --> 00:36:32,160 Speaker 1: to physically hit you. Like your eyes have to be 631 00:36:32,320 --> 00:36:36,919 Speaker 1: physically smacked by photons for you to see them. Your 632 00:36:36,960 --> 00:36:41,440 Speaker 1: ears have to be physically smacked by sound. Waves. It's like, 633 00:36:41,800 --> 00:36:44,319 Speaker 1: you know our sense of touch. We understand you have 634 00:36:44,400 --> 00:36:47,120 Speaker 1: to physically touch something to feel it, but it's the 635 00:36:47,200 --> 00:36:49,319 Speaker 1: same thing with our eyes and our ears, even if 636 00:36:49,320 --> 00:36:51,680 Speaker 1: it doesn't feel that way, because you don't have to 637 00:36:52,080 --> 00:36:54,839 Speaker 1: press a leaf to your eye to see that it's green, 638 00:36:55,480 --> 00:36:59,799 Speaker 1: but you are technically feeling that leaf with your eye 639 00:37:00,000 --> 00:37:03,799 Speaker 1: all because the photons that are bouncing from the leaf 640 00:37:03,840 --> 00:37:07,480 Speaker 1: are hitting your eyeball physically. And that's exactly why things 641 00:37:07,480 --> 00:37:10,840 Speaker 1: that look green are things that reflect green, not things 642 00:37:10,880 --> 00:37:14,160 Speaker 1: that absorb green. Like if you eat a bunch of blueberries, 643 00:37:14,360 --> 00:37:16,520 Speaker 1: it makes you blue on the inside. You might think 644 00:37:16,640 --> 00:37:18,200 Speaker 1: that's the same way it works for light, but the 645 00:37:18,239 --> 00:37:21,239 Speaker 1: reason blueberries are blue is because they reflect blue, they 646 00:37:21,239 --> 00:37:26,080 Speaker 1: don't absorb blue. Isn't that why black things like a 647 00:37:26,160 --> 00:37:29,640 Speaker 1: black shirt gets really hot in the sun because it's 648 00:37:29,800 --> 00:37:33,319 Speaker 1: not it's not that it's absorbing black, which you can't 649 00:37:33,400 --> 00:37:36,640 Speaker 1: really absorb black, because black is just the absence of light. 650 00:37:37,120 --> 00:37:40,520 Speaker 1: It's absorbing that white light, which is a really high 651 00:37:40,600 --> 00:37:43,279 Speaker 1: energy light, which makes it hot. And that's why in 652 00:37:43,320 --> 00:37:46,719 Speaker 1: the desert people wear white because white is more reflective, 653 00:37:46,760 --> 00:37:50,080 Speaker 1: it doesn't absorb as many photons as black. Does, and 654 00:37:50,120 --> 00:37:53,120 Speaker 1: so that's why snow, for example, doesn't melt unless it 655 00:37:53,120 --> 00:37:55,960 Speaker 1: gets dirty. When snow gets dirty, it absorbs more light 656 00:37:56,000 --> 00:37:59,000 Speaker 1: and then it melts. But pure crystal white snow can 657 00:37:59,040 --> 00:38:01,680 Speaker 1: reflect a lot of on light and doesn't melt as quickly. 658 00:38:01,760 --> 00:38:04,680 Speaker 1: And you can actually get sunburned from the reflections of 659 00:38:04,760 --> 00:38:07,640 Speaker 1: snow because it's reflecting a lot of light at you. 660 00:38:08,080 --> 00:38:12,080 Speaker 1: And I learned this while skiing. You can get sunburned 661 00:38:12,120 --> 00:38:16,040 Speaker 1: on the bottom of your nose. Yes, it's fun exactly. 662 00:38:16,120 --> 00:38:19,160 Speaker 1: So now let's trace those photons into your eyes. You say, 663 00:38:19,200 --> 00:38:21,840 Speaker 1: they go through the cornea and the iris and the lens, 664 00:38:22,080 --> 00:38:24,000 Speaker 1: and they hit the retina. And what's going on on 665 00:38:24,080 --> 00:38:26,760 Speaker 1: the retina that allows you to see these things. Well, essentially, 666 00:38:26,840 --> 00:38:30,400 Speaker 1: you have a huge number of sensors, millions and millions 667 00:38:30,440 --> 00:38:33,440 Speaker 1: of these sensors of two kinds. You have the rods 668 00:38:33,560 --> 00:38:36,040 Speaker 1: and you have the cones. Rods are really good at 669 00:38:36,080 --> 00:38:39,120 Speaker 1: seeing small numbers of photons. They're good at seeing in 670 00:38:39,160 --> 00:38:41,279 Speaker 1: the dark, but you only have one kind of them, 671 00:38:41,600 --> 00:38:43,840 Speaker 1: and so they basically just say like yes or no. 672 00:38:44,239 --> 00:38:46,800 Speaker 1: The cones, however, you have three kinds of those, and 673 00:38:46,840 --> 00:38:49,279 Speaker 1: you refer to them earlier as blue, green, and red. 674 00:38:49,440 --> 00:38:52,040 Speaker 1: And the reason we call them that sometimes is because 675 00:38:52,040 --> 00:38:54,880 Speaker 1: they're good at seeing different frequencies of light. It's not 676 00:38:54,920 --> 00:38:57,400 Speaker 1: like they can only see one frequency. There's sort of 677 00:38:57,440 --> 00:38:59,000 Speaker 1: like a width to it. If you look at a 678 00:38:59,000 --> 00:39:02,359 Speaker 1: graph of like how likely one of these cones is 679 00:39:02,760 --> 00:39:05,800 Speaker 1: to see a photon of a different frequency, you see 680 00:39:05,840 --> 00:39:09,200 Speaker 1: that the ones we call s for short wavelength, the 681 00:39:09,200 --> 00:39:12,040 Speaker 1: ones that see blue light, peeking about four hundred and twenty, 682 00:39:12,160 --> 00:39:14,960 Speaker 1: but they can still see four hundred fifty nanimeter photons. 683 00:39:15,120 --> 00:39:18,040 Speaker 1: They're less likely to see five hundred and almost impossible 684 00:39:18,080 --> 00:39:19,759 Speaker 1: for them to see six hundred, but you know it 685 00:39:19,800 --> 00:39:23,239 Speaker 1: never goes to zero. And the red ones, the ones 686 00:39:23,320 --> 00:39:27,080 Speaker 1: we call long cones, those peaking about five hundred and 687 00:39:27,120 --> 00:39:30,120 Speaker 1: sixteen nanimeters, but they could still see a photon at 688 00:39:30,120 --> 00:39:33,319 Speaker 1: four fifties, just less likely. So they're like good at 689 00:39:33,360 --> 00:39:37,120 Speaker 1: different kinds of things. They're more likely or less likely 690 00:39:37,160 --> 00:39:40,000 Speaker 1: to see photons at different frequencies. And that's what your 691 00:39:40,000 --> 00:39:43,040 Speaker 1: brain is pulling together to say, oh, we're seeing something 692 00:39:43,080 --> 00:39:45,880 Speaker 1: that's red because it's tends to be lighting up the 693 00:39:45,960 --> 00:39:48,719 Speaker 1: long cones and not the short cones, or oh we're 694 00:39:48,719 --> 00:39:51,239 Speaker 1: looking at something that deal because it tends to be 695 00:39:51,320 --> 00:39:53,719 Speaker 1: lighting up their short cones and not the medium or 696 00:39:53,800 --> 00:39:56,720 Speaker 1: long cones as much. So there's a lot of interpretation. 697 00:39:56,760 --> 00:39:58,880 Speaker 1: They're just like back when you were talking about how 698 00:39:58,920 --> 00:40:02,320 Speaker 1: the eye evolved, and you're explaining how we have a cave, 699 00:40:02,680 --> 00:40:05,400 Speaker 1: and we're deducing where the light came from based on 700 00:40:05,640 --> 00:40:07,440 Speaker 1: where we are seeing light and where we are not. 701 00:40:07,600 --> 00:40:09,680 Speaker 1: Now we're deducing the color of the source of that 702 00:40:09,800 --> 00:40:12,440 Speaker 1: light based on which cones are lighting up and which 703 00:40:12,440 --> 00:40:17,920 Speaker 1: cones are not. And it's the relative excitement of the cones, 704 00:40:18,200 --> 00:40:22,160 Speaker 1: like if something's getting really lit up versus a little 705 00:40:22,200 --> 00:40:25,320 Speaker 1: bit lit up. That allows us to tell the difference 706 00:40:25,320 --> 00:40:30,080 Speaker 1: between bluish green and a greenish blue exactly. And there's 707 00:40:30,120 --> 00:40:32,719 Speaker 1: a lot of analysis there that's going on in your head. 708 00:40:32,920 --> 00:40:35,480 Speaker 1: And so I was curious, like how this actually works. 709 00:40:35,840 --> 00:40:38,680 Speaker 1: Why is it that this cone is better at that 710 00:40:38,760 --> 00:40:41,319 Speaker 1: frequency of light and this other cone is better at 711 00:40:41,360 --> 00:40:43,840 Speaker 1: the other frequency of light. What is the real mechanism 712 00:40:43,960 --> 00:40:46,440 Speaker 1: of it? So I asked the professor Martin to explain 713 00:40:46,480 --> 00:40:48,759 Speaker 1: to us what is actually happening when photons hit these 714 00:40:48,760 --> 00:40:52,600 Speaker 1: sensitive cells. And here's her explanation. The rods have ward 715 00:40:52,640 --> 00:40:55,800 Speaker 1: option and then the cones have they're just called options, 716 00:40:56,760 --> 00:41:00,319 Speaker 1: and these are proteins that undergo a confirmational chan change 717 00:41:00,640 --> 00:41:03,080 Speaker 1: when a photon hits them. And so the photon hits 718 00:41:03,080 --> 00:41:06,720 Speaker 1: the protein and then it's confirmation changes and that sends 719 00:41:06,719 --> 00:41:09,719 Speaker 1: a signal inside the cell. That is what transmits the 720 00:41:09,760 --> 00:41:12,759 Speaker 1: signal for that detection to our brains. I have an 721 00:41:12,840 --> 00:41:15,720 Speaker 1: understanding of a protein is like a little molecular machine, 722 00:41:16,200 --> 00:41:18,319 Speaker 1: and you're saying it can absorb a single photon and 723 00:41:18,320 --> 00:41:22,240 Speaker 1: that like chunks over mechanically from like one physical shape 724 00:41:22,239 --> 00:41:25,600 Speaker 1: to another physical shape, and that reflects having absorbed that energy. 725 00:41:25,640 --> 00:41:28,000 Speaker 1: And then something detects that the protein has shifted, is 726 00:41:28,000 --> 00:41:30,600 Speaker 1: that a little lever has been pushed by thee. Isn't 727 00:41:30,640 --> 00:41:33,759 Speaker 1: that amazing? So so it undergoes a conformational change, and 728 00:41:33,800 --> 00:41:37,040 Speaker 1: then something on the other side of the cell transmits 729 00:41:37,040 --> 00:41:39,200 Speaker 1: a signal and then that's some you know, that's how 730 00:41:39,239 --> 00:41:42,080 Speaker 1: your brain detects that that you saw that photon. And 731 00:41:42,080 --> 00:41:45,319 Speaker 1: the rods and cones are different in the proteins that 732 00:41:45,360 --> 00:41:47,719 Speaker 1: can absorb the photons, so they're can absorb photons of 733 00:41:47,760 --> 00:41:50,720 Speaker 1: different frequencies because it's a different protein they absorbed photons 734 00:41:50,719 --> 00:41:53,319 Speaker 1: at different frequencies, and the and the reason that they 735 00:41:53,320 --> 00:41:55,760 Speaker 1: have that difference in absorption is all about the protein. 736 00:41:55,840 --> 00:41:58,000 Speaker 1: So it's about the specifics of the you know, the 737 00:41:58,040 --> 00:42:01,400 Speaker 1: amino acid sequence and the structure of the protein. And 738 00:42:01,400 --> 00:42:03,759 Speaker 1: so why is it that the cones can't respond to 739 00:42:03,800 --> 00:42:06,280 Speaker 1: a single photon? Like do they need five or seven? 740 00:42:06,440 --> 00:42:08,880 Speaker 1: Is it because that lever and the protein is harder 741 00:42:08,920 --> 00:42:11,680 Speaker 1: to push? So, yeah, the rood option is the most 742 00:42:11,800 --> 00:42:16,080 Speaker 1: sensitive one. But like that's kind of a weak answer, right, 743 00:42:16,120 --> 00:42:17,719 Speaker 1: Like why is it the most sensitive one? I'm not 744 00:42:17,760 --> 00:42:20,200 Speaker 1: actually sure. Well, speaking of mysteries of the eye, what 745 00:42:20,280 --> 00:42:23,040 Speaker 1: are some sort of frontiers of research? Is there any 746 00:42:23,120 --> 00:42:25,239 Speaker 1: unknown physics that's happening in the eye, or there any 747 00:42:25,280 --> 00:42:28,879 Speaker 1: processes that go on that we don't understand funds? So, 748 00:42:29,000 --> 00:42:31,400 Speaker 1: for one thing, a really active area of research is 749 00:42:31,440 --> 00:42:35,880 Speaker 1: just how do the rhodoptions work? Because um, this is 750 00:42:35,880 --> 00:42:39,480 Speaker 1: one of the fastest known processes in biology, like the 751 00:42:39,520 --> 00:42:42,320 Speaker 1: early steps of what happens when a photon hits that 752 00:42:42,440 --> 00:42:45,800 Speaker 1: rhodopson So I mentioned that it undergoes a confirmational change, 753 00:42:45,800 --> 00:42:48,640 Speaker 1: So it actually has a small molecule that's bound inside 754 00:42:48,680 --> 00:42:52,520 Speaker 1: the protein. That's it's a retinal and it changes confirmation, 755 00:42:53,239 --> 00:42:56,040 Speaker 1: so you know, it goes from like a bent confirmation 756 00:42:56,080 --> 00:42:58,920 Speaker 1: to a straight confirmation. That's what makes the protein undergo 757 00:42:58,960 --> 00:43:03,400 Speaker 1: the confirmational change. But the first steps of that happened 758 00:43:03,480 --> 00:43:06,160 Speaker 1: really really fast, and so you need you need a 759 00:43:06,200 --> 00:43:08,080 Speaker 1: fast laser to be able to study it, and you 760 00:43:08,120 --> 00:43:10,480 Speaker 1: also need to do the whole thing in the dark. Alright, 761 00:43:10,480 --> 00:43:13,480 Speaker 1: So I thought that was super cool that basically we 762 00:43:13,520 --> 00:43:17,800 Speaker 1: have these proteins inside these rods and cones that change 763 00:43:17,800 --> 00:43:21,040 Speaker 1: configuration when a photon hits them. My mental picture is 764 00:43:21,080 --> 00:43:23,480 Speaker 1: like we have a little machine there. I think of 765 00:43:23,560 --> 00:43:27,320 Speaker 1: proteins is little machines, and like the photon like shifts 766 00:43:27,360 --> 00:43:30,680 Speaker 1: a lever, like you know, flips a switch almost physically. 767 00:43:30,719 --> 00:43:33,440 Speaker 1: That's incredible. Do you like to watch videos of Rube 768 00:43:33,440 --> 00:43:38,239 Speaker 1: Goldberg machines. It's like when you have a marble hit 769 00:43:38,280 --> 00:43:41,359 Speaker 1: a thing and then that releases a domino, and then 770 00:43:41,480 --> 00:43:45,120 Speaker 1: soon you've got a teapot boiling, and then that pops 771 00:43:45,160 --> 00:43:47,759 Speaker 1: a balloon and then a hammer lands on a lever. 772 00:43:48,400 --> 00:43:51,440 Speaker 1: That's how I like to visualize a lot of these 773 00:43:51,560 --> 00:43:56,040 Speaker 1: complex cellular processes, and that is very true of how 774 00:43:56,280 --> 00:43:59,600 Speaker 1: these rods and cones work so like you have a 775 00:44:00,040 --> 00:44:04,440 Speaker 1: photon literally hit like a little ever, it's changing the 776 00:44:04,600 --> 00:44:11,759 Speaker 1: molecules shape, which triggers a cascade of responses inside of 777 00:44:11,800 --> 00:44:15,360 Speaker 1: the cell. But you can visualize like a Rube Goldberg 778 00:44:15,440 --> 00:44:18,239 Speaker 1: machine or like a domino effect. And it's not just 779 00:44:18,320 --> 00:44:20,799 Speaker 1: something that happens once and then somebody spends like three 780 00:44:20,800 --> 00:44:23,080 Speaker 1: hours setting it up again, and not just response to 781 00:44:23,120 --> 00:44:26,680 Speaker 1: a photon and then unresponds and gets ready for another photon, 782 00:44:27,000 --> 00:44:30,759 Speaker 1: sometimes like milliseconds later. Right, Rachel was saying, this is 783 00:44:30,800 --> 00:44:34,560 Speaker 1: one of the fastest processes we know of in biology. Yeah, 784 00:44:34,600 --> 00:44:38,120 Speaker 1: and it is interesting because as fast as your cells 785 00:44:38,200 --> 00:44:41,640 Speaker 1: can be in responding to this, you can also overload 786 00:44:41,719 --> 00:44:45,759 Speaker 1: your cells if they're too sensitive, which is also it's 787 00:44:45,800 --> 00:44:48,479 Speaker 1: not just happening on the cellular level. This is something 788 00:44:48,520 --> 00:44:52,080 Speaker 1: that happens inside the brain. So as you're getting this 789 00:44:52,200 --> 00:44:55,440 Speaker 1: information right, because these sensors are sensing it and sending 790 00:44:55,480 --> 00:44:58,359 Speaker 1: that information to the brain, But it doesn't just go 791 00:44:58,480 --> 00:45:00,760 Speaker 1: directly to brain and say hey, look at this color. 792 00:45:01,320 --> 00:45:04,279 Speaker 1: It has to activate your neurons and then that's a 793 00:45:04,320 --> 00:45:07,640 Speaker 1: whole other roup Goldberg machine that happens at the neural level, 794 00:45:07,760 --> 00:45:11,160 Speaker 1: and you may have some threshold of activation for these neurons, 795 00:45:11,200 --> 00:45:14,560 Speaker 1: and so you get some really weird things that happened 796 00:45:14,640 --> 00:45:18,840 Speaker 1: with this interplay between the sensitivity of your photoreceptors in 797 00:45:18,880 --> 00:45:21,520 Speaker 1: your eye and the sensitivity of your neurons and your 798 00:45:21,560 --> 00:45:24,439 Speaker 1: occipital lobe, the vision center of the brain. And that's 799 00:45:24,440 --> 00:45:27,000 Speaker 1: why if you like stare at a bright color and 800 00:45:27,000 --> 00:45:28,719 Speaker 1: then you look at the wall, you see this like 801 00:45:28,840 --> 00:45:32,480 Speaker 1: weird afterimage. So it's a really interesting, I guess, just 802 00:45:32,800 --> 00:45:37,279 Speaker 1: thinking about these little, tiny machines working really hard, but 803 00:45:37,360 --> 00:45:39,600 Speaker 1: it's happening so quickly. It's the kind of thing that 804 00:45:39,640 --> 00:45:42,520 Speaker 1: makes you amaze that it ever works, and suddenly doubt 805 00:45:42,520 --> 00:45:44,800 Speaker 1: that it will continue to. You know, whenever I learned 806 00:45:44,840 --> 00:45:48,000 Speaker 1: how delicate these things are inside my body, I'm immediately terrified, like, 807 00:45:48,040 --> 00:45:50,760 Speaker 1: oh my gosh, what's how has this thing been going 808 00:45:50,800 --> 00:45:53,400 Speaker 1: for so long? Isn't it about to just fall apart? 809 00:45:53,640 --> 00:45:56,400 Speaker 1: But it's amazing it really works. Something was really interesting 810 00:45:56,440 --> 00:45:59,840 Speaker 1: to me was thinking about why the cones are sensitive 811 00:45:59,880 --> 00:46:03,120 Speaker 1: to different frequencies, and it's because they have different proteins 812 00:46:03,160 --> 00:46:06,400 Speaker 1: inside them which are better or worse at absorbing photons 813 00:46:06,440 --> 00:46:10,200 Speaker 1: of different frequencies, and why the rods are more sensitive 814 00:46:10,200 --> 00:46:13,880 Speaker 1: than the cones. Why make cones less sensitive than rods 815 00:46:14,080 --> 00:46:16,960 Speaker 1: and why make rods more sensitive than cones. I think 816 00:46:17,000 --> 00:46:19,680 Speaker 1: the answer is just diversification. Like you want to do 817 00:46:19,719 --> 00:46:21,759 Speaker 1: two different things. One is you want to be able 818 00:46:21,760 --> 00:46:23,719 Speaker 1: to see in low light conditions, and the others you 819 00:46:23,719 --> 00:46:25,359 Speaker 1: want to be able to see color so you can 820 00:46:25,600 --> 00:46:28,439 Speaker 1: spot that fruit or spot that predator. And being able 821 00:46:28,480 --> 00:46:32,040 Speaker 1: to see in low light conditions is actually somewhat mutually 822 00:46:32,120 --> 00:46:35,319 Speaker 1: exclusive to being able to see in higher light conditions, 823 00:46:35,360 --> 00:46:39,719 Speaker 1: because that requires your rods to be really, really sensitive 824 00:46:39,800 --> 00:46:43,000 Speaker 1: to light. And the more sensitive they are to light, 825 00:46:43,200 --> 00:46:47,080 Speaker 1: the more hyperactive they'll be when you have too much lights. 826 00:46:47,080 --> 00:46:51,440 Speaker 1: So your rods aren't that useful in highlight conditions, but 827 00:46:51,520 --> 00:46:54,319 Speaker 1: they're really useful in low light conditions. That's why if 828 00:46:54,360 --> 00:46:58,080 Speaker 1: you've ever stepped from a bright theater lobby into a 829 00:46:58,200 --> 00:47:01,360 Speaker 1: dark movie theater, you can't see where you're going and 830 00:47:01,440 --> 00:47:03,400 Speaker 1: you fall over and you land in a puddle of 831 00:47:03,719 --> 00:47:08,280 Speaker 1: coke and popcorn. Uh, it's because your eyes haven't adjusted 832 00:47:08,320 --> 00:47:11,440 Speaker 1: to the dark. But then as those rods kind of 833 00:47:11,480 --> 00:47:15,920 Speaker 1: like calm down, they adjust to that low light of 834 00:47:16,040 --> 00:47:18,840 Speaker 1: the dark room, and you can actually see in the dark. 835 00:47:19,120 --> 00:47:23,759 Speaker 1: And so yeah, the the rods being hyper sensitive is 836 00:47:23,840 --> 00:47:26,680 Speaker 1: useful for us to be able to see in low 837 00:47:26,760 --> 00:47:29,120 Speaker 1: light conditions. But then we have the cones that allow 838 00:47:29,239 --> 00:47:31,839 Speaker 1: us to see in brighter light, and not only that, 839 00:47:31,960 --> 00:47:34,680 Speaker 1: but differentiate color. And the cones are in the very 840 00:47:34,719 --> 00:47:37,200 Speaker 1: center of your eyeballs. When you're just looking straight at something, 841 00:47:37,239 --> 00:47:39,640 Speaker 1: you're good at seeing colors, and the rods tend to 842 00:47:39,640 --> 00:47:42,080 Speaker 1: be distributed in the other parts of the eyeball, which 843 00:47:42,120 --> 00:47:45,640 Speaker 1: means that like your peripheral vision is better at seeing 844 00:47:45,640 --> 00:47:48,400 Speaker 1: in low light conditions than your central vision is. So 845 00:47:48,480 --> 00:47:50,719 Speaker 1: for example, if you're an amateur astronomer and you like 846 00:47:50,800 --> 00:47:53,400 Speaker 1: looking at the night sky, sometimes you might notice a 847 00:47:53,480 --> 00:47:55,719 Speaker 1: star out of the corner of your eye. If you 848 00:47:55,760 --> 00:47:58,719 Speaker 1: then turn your eyeball to it, it can disappear. And 849 00:47:58,760 --> 00:48:01,280 Speaker 1: that's why because the scent or of your eyeball doesn't 850 00:48:01,320 --> 00:48:03,239 Speaker 1: have a lot of rods. So if you want to 851 00:48:03,239 --> 00:48:06,520 Speaker 1: observe faint things in the sky, don't look straight at 852 00:48:06,520 --> 00:48:10,040 Speaker 1: them where they disappear. It seems almost magical, which is 853 00:48:10,560 --> 00:48:13,839 Speaker 1: interesting evolutionarily right, because you think of when we would 854 00:48:13,960 --> 00:48:17,880 Speaker 1: need this low light vision, it probably would be at 855 00:48:18,000 --> 00:48:20,799 Speaker 1: night when we're trying to avoid getting eaten by a 856 00:48:20,840 --> 00:48:24,520 Speaker 1: nocturnal predator, so being able to see movement out of 857 00:48:24,560 --> 00:48:28,120 Speaker 1: the corner of our eye and flee or hide is 858 00:48:28,200 --> 00:48:31,560 Speaker 1: really important. Whereas in lower light having being able to 859 00:48:31,640 --> 00:48:35,719 Speaker 1: like focus on something specifically, Well, this is when we're sleeping. 860 00:48:35,800 --> 00:48:38,759 Speaker 1: We don't really need to hunt at night. We're not 861 00:48:38,880 --> 00:48:43,200 Speaker 1: nocturnal predators, so our eyes are optimized for being able 862 00:48:43,239 --> 00:48:47,000 Speaker 1: to see somewhat in low lights so we can protect ourselves, 863 00:48:47,120 --> 00:48:52,399 Speaker 1: but not optimized for being predators. Nocturnal predators, that's right. 864 00:48:52,440 --> 00:48:55,120 Speaker 1: And some of us have a different kind of eyeball 865 00:48:55,480 --> 00:48:57,840 Speaker 1: than the rest of us. Most of us have three 866 00:48:58,040 --> 00:49:01,240 Speaker 1: kinds of cones, so we can see light that peaks 867 00:49:01,239 --> 00:49:04,560 Speaker 1: in three different places. But some people have special eyes. 868 00:49:04,640 --> 00:49:08,200 Speaker 1: They are called tetra chromats, and they have a fourth 869 00:49:08,400 --> 00:49:11,520 Speaker 1: kind of cone, which means they have another kind of 870 00:49:11,560 --> 00:49:14,200 Speaker 1: thing in their eye that peaks at a different place. 871 00:49:14,239 --> 00:49:18,279 Speaker 1: It peaks bluer than blue on the spectrum. And this 872 00:49:18,320 --> 00:49:20,800 Speaker 1: to me was fascinating when I first learned about I thought, wow, 873 00:49:20,880 --> 00:49:23,279 Speaker 1: maybe they can see another kind of color. Maybe this 874 00:49:23,360 --> 00:49:26,240 Speaker 1: is like my childhood fantasy. There's like a super blue 875 00:49:26,239 --> 00:49:29,400 Speaker 1: that they can see in their minds that we can't see. 876 00:49:29,560 --> 00:49:31,759 Speaker 1: But unfortunately it's not like that. What it means is 877 00:49:31,800 --> 00:49:35,280 Speaker 1: that they are better at distinguishing between shades of blue. 878 00:49:35,280 --> 00:49:38,000 Speaker 1: They're like my daughter who can tell teal from slightly 879 00:49:38,080 --> 00:49:41,280 Speaker 1: not teal because they get more information about the relative 880 00:49:41,320 --> 00:49:45,600 Speaker 1: intensities of those photons, and so they're better at distinguishing colors. 881 00:49:45,760 --> 00:49:49,600 Speaker 1: They can't necessarily see or experience any new colors. And 882 00:49:49,800 --> 00:49:52,400 Speaker 1: I mean, on the opposite end of the visual spectrum, 883 00:49:52,440 --> 00:49:55,880 Speaker 1: you have people who are color blind or partially color blind. 884 00:49:55,920 --> 00:50:00,279 Speaker 1: And it's not that people necessarily only see in grace gale, 885 00:50:00,360 --> 00:50:03,239 Speaker 1: but they can be like blue green color blind, where 886 00:50:03,239 --> 00:50:07,640 Speaker 1: they have trouble distinguishing between blues and greens. So yeah, 887 00:50:07,680 --> 00:50:11,799 Speaker 1: there's this whole range of human vision, and it makes 888 00:50:11,840 --> 00:50:15,399 Speaker 1: me wonder, like your earlier question, whether there's a lot 889 00:50:15,440 --> 00:50:20,000 Speaker 1: of difference in vision amongst people who are not necessarily 890 00:50:20,040 --> 00:50:24,200 Speaker 1: tetrachromace or people who have color blindness, but just like 891 00:50:24,560 --> 00:50:30,040 Speaker 1: whether vision comes in a spectrum like many other human experiences, right, 892 00:50:30,080 --> 00:50:33,560 Speaker 1: because people experience chocolate differently, right, Like some people actually 893 00:50:33,640 --> 00:50:36,719 Speaker 1: enjoy white chocolate and aren't just pretending. You know, it's 894 00:50:36,719 --> 00:50:43,320 Speaker 1: a mystery they're just wrong. Thank you, thank you. People 895 00:50:43,360 --> 00:50:47,400 Speaker 1: respond subjectively very differently to stimuli, and so it would 896 00:50:47,440 --> 00:50:51,360 Speaker 1: make sense if people responded differently to different kinds of photons. 897 00:50:51,560 --> 00:50:53,360 Speaker 1: And we know that out there in the animal kingdom 898 00:50:53,360 --> 00:50:57,320 Speaker 1: there's also an incredible wide variety of eyeballs, right, Different 899 00:50:57,400 --> 00:51:00,160 Speaker 1: kinds of critters are have evolved too, dear for in 900 00:51:00,200 --> 00:51:03,480 Speaker 1: scenarios where they need more or less kinds of vision. 901 00:51:03,719 --> 00:51:06,880 Speaker 1: For example, we know that owls have incredible vision, especially 902 00:51:06,920 --> 00:51:10,200 Speaker 1: in low light because they have an enormous number of these. 903 00:51:10,320 --> 00:51:14,440 Speaker 1: Rods and geckos have really good actually night color vision 904 00:51:15,080 --> 00:51:17,760 Speaker 1: so that they can survive. Plus they have a tongue 905 00:51:17,760 --> 00:51:20,399 Speaker 1: that lets them clean their own eyeballs, which I think 906 00:51:20,480 --> 00:51:24,279 Speaker 1: is pretty crazy. It's adorable. Yeah, no, I It is 907 00:51:24,360 --> 00:51:28,200 Speaker 1: one of the most fascinating things in evolutionary biology, the 908 00:51:28,320 --> 00:51:35,080 Speaker 1: difference in vision. It's mysterious because we cannot objectively measure 909 00:51:35,120 --> 00:51:38,560 Speaker 1: what an animals experience of vision is. We can only 910 00:51:39,160 --> 00:51:42,960 Speaker 1: guests basically based on their eye structure and based on 911 00:51:43,000 --> 00:51:46,879 Speaker 1: their brain. So there, when you research it can come 912 00:51:46,920 --> 00:51:50,560 Speaker 1: to some really surprising results that are hard to conceptualize. So, 913 00:51:50,640 --> 00:51:56,440 Speaker 1: for instance, rants actually have double vision and can somewhat 914 00:51:56,480 --> 00:52:00,520 Speaker 1: move their eyes independently of each other. And we discovered 915 00:52:00,520 --> 00:52:05,000 Speaker 1: this by putting little teeny tiny high speed cameras attached 916 00:52:05,000 --> 00:52:08,240 Speaker 1: to little hats on rats and looking at their eye gays, 917 00:52:08,640 --> 00:52:11,120 Speaker 1: and they found that their eye gays indicates that they 918 00:52:11,160 --> 00:52:14,560 Speaker 1: prioritize keeping a view of the sky as well as 919 00:52:14,560 --> 00:52:18,120 Speaker 1: their surroundings so that they can avoid that owl who 920 00:52:18,400 --> 00:52:21,439 Speaker 1: has that great night vision. So rats are running along 921 00:52:21,480 --> 00:52:23,920 Speaker 1: the ground with one eye up and one eye down. 922 00:52:24,280 --> 00:52:29,399 Speaker 1: That's crazy, basically, Yeah. And what's so weird is that 923 00:52:29,600 --> 00:52:33,560 Speaker 1: researchers think that these fields of vision in either I 924 00:52:33,800 --> 00:52:37,280 Speaker 1: are too different to be fused into a single image. 925 00:52:37,320 --> 00:52:41,680 Speaker 1: So there's a possibility that rants basically have like two 926 00:52:41,719 --> 00:52:45,320 Speaker 1: TV monitors in their head that they're both keeping track 927 00:52:45,400 --> 00:52:51,400 Speaker 1: of and unlike us, where we have basically one combined image. 928 00:52:51,760 --> 00:52:55,880 Speaker 1: And I mean just the the ingenuity that animals have 929 00:52:55,920 --> 00:52:59,279 Speaker 1: when it comes to eyeballs can be completely baffling. Like 930 00:52:59,360 --> 00:53:01,360 Speaker 1: this is a fun named one, but it's a brown 931 00:53:01,440 --> 00:53:06,200 Speaker 1: nose spook fish, which is a species of barrel eye fish. 932 00:53:06,360 --> 00:53:10,160 Speaker 1: It's this very weird looking fish. It's not very big. 933 00:53:10,200 --> 00:53:13,440 Speaker 1: It's like about seven inches maybe like the length of 934 00:53:13,440 --> 00:53:16,680 Speaker 1: your hand, it's got a transparent body. It looks kind 935 00:53:16,680 --> 00:53:19,680 Speaker 1: of creepy, like some kind of ghost of a fish. 936 00:53:20,040 --> 00:53:23,960 Speaker 1: And it is actually only vertebrate that is known to, 937 00:53:24,760 --> 00:53:29,120 Speaker 1: in addition to a lens, have an actual mirror in 938 00:53:29,160 --> 00:53:33,760 Speaker 1: their eye. So the way that animals can have mirrors 939 00:53:33,880 --> 00:53:37,759 Speaker 1: is they use guanting crystals to form a mirror, because 940 00:53:37,760 --> 00:53:41,520 Speaker 1: a guanting crystal is a protein that an organic animal 941 00:53:41,640 --> 00:53:47,600 Speaker 1: can produce, but it's structure is reflective, and so this 942 00:53:47,680 --> 00:53:51,200 Speaker 1: is actually also used in scallops. Scalops have eyes. In fact, 943 00:53:51,200 --> 00:53:54,160 Speaker 1: they have hundreds of eyes, which is a fun thought 944 00:53:54,320 --> 00:53:57,520 Speaker 1: next time you enjoy your scalp. But yes, so so 945 00:53:57,560 --> 00:54:02,839 Speaker 1: this brown snout spook fish, it has a normal eye 946 00:54:03,239 --> 00:54:07,160 Speaker 1: that looks upwards, and then in addition to that, it 947 00:54:07,200 --> 00:54:09,680 Speaker 1: actually has an annex ee like just stuck to the 948 00:54:09,719 --> 00:54:12,880 Speaker 1: side of it, like a side view mirror on a car. 949 00:54:13,280 --> 00:54:16,200 Speaker 1: It has a mirror that allows it to look downwards. 950 00:54:16,200 --> 00:54:19,560 Speaker 1: So this fish can look both upwards and downwards at 951 00:54:19,600 --> 00:54:22,279 Speaker 1: the same time. Well, that's a very useful kind of 952 00:54:22,320 --> 00:54:24,839 Speaker 1: side eye. One of my favorite kind of eyeballs out 953 00:54:24,880 --> 00:54:27,720 Speaker 1: there in the world is the mantis shrimp. The mantis 954 00:54:27,719 --> 00:54:30,680 Speaker 1: shrimp doesn't just have three or four kinds of cones. 955 00:54:30,960 --> 00:54:35,000 Speaker 1: They estimate it might have fifteen or sixteen different kinds 956 00:54:35,000 --> 00:54:37,279 Speaker 1: of cones in its eye. And when you first read 957 00:54:37,320 --> 00:54:39,360 Speaker 1: about that, you think, wow, the mantis strip must have 958 00:54:39,440 --> 00:54:43,239 Speaker 1: like a really vibrant visual experience. It's like MARTAGRAI every 959 00:54:43,280 --> 00:54:45,200 Speaker 1: day for the mantis shrimp. Right, Well, it turns out 960 00:54:45,239 --> 00:54:49,000 Speaker 1: the mantis strip actually isn't any better than humans at 961 00:54:49,000 --> 00:54:51,960 Speaker 1: distinguishing colors. They do these experiments where they train the 962 00:54:52,000 --> 00:54:54,400 Speaker 1: shrimp like go to food if you can see the 963 00:54:54,440 --> 00:54:57,359 Speaker 1: difference between the colors, and they aren't any better at 964 00:54:57,360 --> 00:54:59,600 Speaker 1: distinguishing colors than we are. And we only have three 965 00:54:59,680 --> 00:55:02,000 Speaker 1: kinds of codes. And the reason is that the mantis 966 00:55:02,000 --> 00:55:05,920 Speaker 1: shrimp basically has much more specific hardware, but it doesn't 967 00:55:05,920 --> 00:55:08,560 Speaker 1: have the processing power to really take advantage of that. 968 00:55:08,760 --> 00:55:12,040 Speaker 1: Their brains are really simple. So we have like simpler 969 00:55:12,120 --> 00:55:16,040 Speaker 1: hardware only three sensors, but very complicated software to interpret 970 00:55:16,200 --> 00:55:18,600 Speaker 1: and analyze that. And the manti strimp has made like 971 00:55:18,640 --> 00:55:21,720 Speaker 1: a different optimization, like go all in on the hardware 972 00:55:21,760 --> 00:55:25,839 Speaker 1: and have really simple software to interpret it. It's pretty fascinating, right, 973 00:55:25,880 --> 00:55:29,200 Speaker 1: And the reason for that is that the mantis shrimp 974 00:55:29,280 --> 00:55:33,439 Speaker 1: is optimizing the speed of its site rather than sort 975 00:55:33,440 --> 00:55:36,680 Speaker 1: of the detail of its perception. So it's thought that 976 00:55:36,719 --> 00:55:41,080 Speaker 1: with less software and more hardware, you can actually sense 977 00:55:41,120 --> 00:55:44,239 Speaker 1: something much more quickly, like the because the speed of 978 00:55:44,360 --> 00:55:47,759 Speaker 1: light is quite fast. Uh. And then if you can 979 00:55:47,920 --> 00:55:52,360 Speaker 1: have these photoreceptors pick up on that photon really quickly 980 00:55:52,360 --> 00:55:55,799 Speaker 1: because you just have so many, then even if your 981 00:55:55,920 --> 00:55:58,879 Speaker 1: software is relatively simple of just like, hey, there's a thing, 982 00:55:59,320 --> 00:56:03,320 Speaker 1: if it's quick enough, it will have incredible reflexes. That 983 00:56:03,400 --> 00:56:04,799 Speaker 1: makes a lot of sense of speed of light is 984 00:56:04,800 --> 00:56:07,560 Speaker 1: faster than the speed of brains. I definitely, I definitely 985 00:56:07,560 --> 00:56:10,759 Speaker 1: don't think at the speed of light and like, is 986 00:56:10,800 --> 00:56:13,160 Speaker 1: that a shark? Or is that dinner? Oops? Too late, 987 00:56:13,239 --> 00:56:17,000 Speaker 1: I'm being eaten already. Well. One of my favorite stories 988 00:56:17,040 --> 00:56:20,680 Speaker 1: about color and animals comes again from Rachel Martin, who 989 00:56:20,680 --> 00:56:23,319 Speaker 1: told us the story about how birds that seems sort 990 00:56:23,320 --> 00:56:25,839 Speaker 1: of boring and blue turned out to be actually ultra 991 00:56:25,920 --> 00:56:29,160 Speaker 1: violet and spectacular. So here's Rachel talking about one of 992 00:56:29,160 --> 00:56:33,160 Speaker 1: her favorite studies. One of my favorite papers in this 993 00:56:33,239 --> 00:56:37,880 Speaker 1: area is one where these scientists were looking at blue tips, 994 00:56:37,880 --> 00:56:42,040 Speaker 1: so a little birds, and they thought that these birds 995 00:56:42,040 --> 00:56:45,960 Speaker 1: didn't really have a strong sexual selection system because they 996 00:56:46,000 --> 00:56:47,480 Speaker 1: all kind of look the same. And you know, for 997 00:56:47,520 --> 00:56:49,520 Speaker 1: a lot of birds, like the males are really pretty 998 00:56:49,560 --> 00:56:52,360 Speaker 1: and showy, and they have markings that the females are choosing, 999 00:56:53,200 --> 00:56:55,720 Speaker 1: and for these birds, they didn't seem to They seemed 1000 00:56:55,719 --> 00:56:58,760 Speaker 1: to all look the same. And then somebody finally thought 1001 00:56:58,880 --> 00:57:03,000 Speaker 1: of doing some ex erments with whether these they had 1002 00:57:03,000 --> 00:57:06,120 Speaker 1: pigments in the UV. So they put m vast lean 1003 00:57:06,239 --> 00:57:08,799 Speaker 1: on the bird's heads. So they discovered that they had 1004 00:57:08,920 --> 00:57:12,440 Speaker 1: some markings in the UV, like on their heads, and 1005 00:57:12,440 --> 00:57:14,760 Speaker 1: so if they put vast lean over it so that 1006 00:57:14,760 --> 00:57:20,000 Speaker 1: that blocked the UV, the females, you know, didn't you 1007 00:57:20,080 --> 00:57:22,800 Speaker 1: weren't able to see those markings, and so then there 1008 00:57:22,840 --> 00:57:24,920 Speaker 1: was a big difference in the sexual selection. So the 1009 00:57:24,960 --> 00:57:27,320 Speaker 1: males that were really popular before because they had these 1010 00:57:27,360 --> 00:57:29,720 Speaker 1: beautiful UV markings on their heads, when you put bass 1011 00:57:29,800 --> 00:57:32,400 Speaker 1: lean on them, then they don't get any attention because 1012 00:57:32,800 --> 00:57:36,680 Speaker 1: the females can't see this. And so it led to 1013 00:57:37,080 --> 00:57:39,600 Speaker 1: you know, one of my favorite paper titles of all time, 1014 00:57:39,880 --> 00:57:43,400 Speaker 1: which was blue Tips Are Ultra Violet Tits. I love 1015 00:57:43,400 --> 00:57:45,320 Speaker 1: that story and I wish I get to write a 1016 00:57:45,320 --> 00:57:48,320 Speaker 1: paper using the phrase ultra violet tits. I wish I 1017 00:57:48,320 --> 00:57:53,800 Speaker 1: had gotten to rub vassilene on a bird's head. So 1018 00:57:53,880 --> 00:57:57,640 Speaker 1: many adventures in science, you know, the more animals we 1019 00:57:57,760 --> 00:58:01,800 Speaker 1: stick under black light them, or we're finding have this 1020 00:58:02,000 --> 00:58:07,000 Speaker 1: like biofluorescence exactly. So we see a little slice of 1021 00:58:07,040 --> 00:58:09,680 Speaker 1: the universe that's out there, and a lot of animals 1022 00:58:09,720 --> 00:58:13,120 Speaker 1: can see further into that spectrum and are advertising to 1023 00:58:13,200 --> 00:58:16,000 Speaker 1: each other in that spectrum, and so it's like we're 1024 00:58:16,000 --> 00:58:18,520 Speaker 1: not seeing what's going on out there. Maybe there are 1025 00:58:18,560 --> 00:58:21,360 Speaker 1: some animals that can see neutrinos and are sending neutrino 1026 00:58:21,480 --> 00:58:24,040 Speaker 1: messages to each other, you know, they have like pigments 1027 00:58:24,080 --> 00:58:27,360 Speaker 1: in their feathers that glow in neutrinos. No, I'm sure 1028 00:58:27,400 --> 00:58:30,120 Speaker 1: they don't. But that sounds like a fun science fiction story. 1029 00:58:30,240 --> 00:58:33,080 Speaker 1: But let's get back to the actual science of the universe. 1030 00:58:33,120 --> 00:58:35,720 Speaker 1: And I want to answer our question about whether a 1031 00:58:35,800 --> 00:58:40,000 Speaker 1: human eye can respond to a single polton human eyeball 1032 00:58:40,040 --> 00:58:43,440 Speaker 1: as a quantum device. But first let's take a second break. 1033 00:58:56,080 --> 00:58:58,600 Speaker 1: All right, we're back, and we have explained to ourselves 1034 00:58:58,720 --> 00:59:01,960 Speaker 1: how the eyeball works, how it receives photon, how it 1035 00:59:02,040 --> 00:59:06,280 Speaker 1: triggers this ridiculous Rube Goldberg machine of flipping levers and 1036 00:59:06,360 --> 00:59:09,960 Speaker 1: rolling balls and cascading signals so that you can experience 1037 00:59:10,160 --> 00:59:14,560 Speaker 1: the reddest read that there is. Yeah, I'm really excited 1038 00:59:14,600 --> 00:59:19,160 Speaker 1: about this because I would love to see a single photon. 1039 00:59:19,760 --> 00:59:23,160 Speaker 1: They're responsible for so much stuff that happens in the universe, 1040 00:59:23,160 --> 00:59:25,720 Speaker 1: and I'd like to personally thank it for being there. 1041 00:59:25,840 --> 00:59:27,920 Speaker 1: And we could finally answer one of the most ancient 1042 00:59:27,960 --> 00:59:31,600 Speaker 1: questions in philosophy, which is what does a photon look like? 1043 00:59:31,960 --> 00:59:34,520 Speaker 1: But it's interesting and relevant to physics because if you 1044 00:59:34,560 --> 00:59:36,919 Speaker 1: look up at the night sky, you see some things 1045 00:59:36,920 --> 00:59:39,960 Speaker 1: that are very bright, the moon or nearby planets and stars, 1046 00:59:40,200 --> 00:59:42,680 Speaker 1: but you also see some things that are very, very dim, 1047 00:59:42,800 --> 00:59:46,080 Speaker 1: just at the edge of your perception. And I've often wondered, 1048 00:59:46,080 --> 00:59:48,640 Speaker 1: when looking at the night sky, how many photons am 1049 00:59:48,680 --> 00:59:53,000 Speaker 1: I seeing? You know, imagine some incredibly huge, bright star 1050 00:59:53,200 --> 00:59:56,440 Speaker 1: that's billions and billions of miles away, shooting ten to 1051 00:59:56,440 --> 00:59:59,800 Speaker 1: the fifty photons per second out into the cosmos. All 1052 00:59:59,840 --> 01:00:02,720 Speaker 1: the those photons, just a few have managed to cross 1053 01:00:02,840 --> 01:00:06,720 Speaker 1: that enormous ocean of dark and hit your eyeball. But 1054 01:00:06,760 --> 01:00:09,800 Speaker 1: it makes me wonder how many photons have to make 1055 01:00:09,840 --> 01:00:13,280 Speaker 1: it before I can see that star. What happens to 1056 01:00:13,360 --> 01:00:17,840 Speaker 1: those photons on the way from the star to our eyeball? 1057 01:00:17,960 --> 01:00:21,800 Speaker 1: Do they get knocked around by other particles? They have 1058 01:00:21,840 --> 01:00:24,880 Speaker 1: a great adventure along the way, They make friends, they 1059 01:00:25,000 --> 01:00:28,800 Speaker 1: you know, complete quests. No, it's incredible. Mostly those photons 1060 01:00:28,840 --> 01:00:32,080 Speaker 1: just fly unimpeded through the universe because space is mostly 1061 01:00:32,120 --> 01:00:35,640 Speaker 1: transparent to those photons. There are things out there, the 1062 01:00:35,680 --> 01:00:39,120 Speaker 1: solar wind and particles that will interact with really high 1063 01:00:39,240 --> 01:00:42,480 Speaker 1: energy photons, but lower energy photons like the ones in 1064 01:00:42,480 --> 01:00:46,240 Speaker 1: the visible spectrum, can mostly fly untouched through space. The 1065 01:00:46,320 --> 01:00:48,800 Speaker 1: last thing they interacted with was the surface of the Sun, 1066 01:00:48,840 --> 01:00:51,520 Speaker 1: and the next thing they interact with is your eyeball. 1067 01:00:51,680 --> 01:00:53,720 Speaker 1: The reason, of course you don't see ten to the 1068 01:00:53,800 --> 01:00:57,080 Speaker 1: fifty photons from that star is just because the photons 1069 01:00:57,080 --> 01:00:59,720 Speaker 1: are going in every single direction. So if you have 1070 01:00:59,760 --> 01:01:02,440 Speaker 1: ten of the fifty covering the surface of the star 1071 01:01:02,760 --> 01:01:05,680 Speaker 1: and they all shoot out than a year later, now 1072 01:01:05,720 --> 01:01:08,680 Speaker 1: that same number of photons is painting the inside of 1073 01:01:08,720 --> 01:01:11,479 Speaker 1: a spear that has a radius of one light year, 1074 01:01:11,800 --> 01:01:14,880 Speaker 1: and so like per area, there are many fewer photons 1075 01:01:15,040 --> 01:01:17,960 Speaker 1: by the time it gets to you, billions of miles away, 1076 01:01:18,080 --> 01:01:21,320 Speaker 1: there's just very few photons per square meter. That's why 1077 01:01:21,320 --> 01:01:23,960 Speaker 1: the star feels distant, and that's why the intensity of 1078 01:01:24,040 --> 01:01:27,880 Speaker 1: light falls like one over the radius squared, because that's 1079 01:01:27,880 --> 01:01:30,280 Speaker 1: the surface area of the inside of a sphere of 1080 01:01:30,320 --> 01:01:32,760 Speaker 1: that radius. Well, I'm glad it's a little bit diffused, 1081 01:01:32,880 --> 01:01:35,960 Speaker 1: because otherwise I think it might just kind of instantly 1082 01:01:36,080 --> 01:01:39,560 Speaker 1: vaporize our eyeballs. And it's a question that scientists have 1083 01:01:39,680 --> 01:01:43,360 Speaker 1: been asking since we understood what photons were like, could 1084 01:01:43,360 --> 01:01:46,680 Speaker 1: we see an individual photon? Is that even possible? At first, 1085 01:01:46,680 --> 01:01:48,959 Speaker 1: we have to separate into two questions. One is could 1086 01:01:48,960 --> 01:01:51,920 Speaker 1: you see a photon which hits the outside of your eye? 1087 01:01:52,320 --> 01:01:54,200 Speaker 1: And the second is could you see a photon which 1088 01:01:54,240 --> 01:01:57,480 Speaker 1: hits the actual receptors on the back of your eye? 1089 01:01:57,640 --> 01:01:59,960 Speaker 1: Because it turns out something that's pretty easy to measure 1090 01:02:00,160 --> 01:02:02,400 Speaker 1: is the efficiency for photons to get to the back 1091 01:02:02,520 --> 01:02:05,920 Speaker 1: of your eyeball. And only like one inten photons that 1092 01:02:06,040 --> 01:02:08,640 Speaker 1: hits the surface of your eye actually makes it to 1093 01:02:08,720 --> 01:02:11,960 Speaker 1: the retina. Is it getting uh, sort of lost on 1094 01:02:12,040 --> 01:02:14,880 Speaker 1: the way, is it not reaching the pupil or is 1095 01:02:14,880 --> 01:02:19,280 Speaker 1: it bouncing off something on your eye before reaching the 1096 01:02:19,320 --> 01:02:21,640 Speaker 1: back of your eye? Yeah, they get scattered and they 1097 01:02:21,640 --> 01:02:25,080 Speaker 1: get absorbed. Remember that has light traveled through materials. If 1098 01:02:25,120 --> 01:02:28,440 Speaker 1: you change the reflectivity or basically the index of refraction 1099 01:02:28,480 --> 01:02:31,800 Speaker 1: of the material, you're gonna get some reflection at that surface. 1100 01:02:32,240 --> 01:02:35,640 Speaker 1: Even when photons go from air, which is transparent, to glass, 1101 01:02:35,680 --> 01:02:39,080 Speaker 1: which is transparent, there's always some reflection. And so as 1102 01:02:39,080 --> 01:02:41,360 Speaker 1: you go through the vitreous humor and go through the 1103 01:02:41,440 --> 01:02:43,840 Speaker 1: lens and go through the cornea, there's little bits of 1104 01:02:43,840 --> 01:02:47,160 Speaker 1: reflection here and there and scattering and absorption. It's not 1105 01:02:47,200 --> 01:02:51,680 Speaker 1: a transparent so only one in ten photons actually makes 1106 01:02:51,680 --> 01:02:54,360 Speaker 1: it to the back of the eyeball, which is crazy. Yeah, 1107 01:02:54,400 --> 01:02:57,760 Speaker 1: it seems like we're losing a lot of photons on 1108 01:02:57,800 --> 01:03:00,400 Speaker 1: the way over there. We gotta put some like signs 1109 01:03:00,520 --> 01:03:04,720 Speaker 1: up on our eyeballs, like photons inter here don't get lost. 1110 01:03:05,000 --> 01:03:07,840 Speaker 1: So people started doing experiments to see how sensitive the 1111 01:03:07,880 --> 01:03:10,920 Speaker 1: eye was. Back in like the nineteen forties, they didn't 1112 01:03:10,920 --> 01:03:15,360 Speaker 1: experiment Columbia University where they shot very very low intensity 1113 01:03:15,480 --> 01:03:18,200 Speaker 1: light into the eyeball to try to understand what the 1114 01:03:18,240 --> 01:03:21,000 Speaker 1: threshold was. But back then they didn't have like a 1115 01:03:21,040 --> 01:03:24,160 Speaker 1: great understanding of quantum mechanics and quantum optics, it was 1116 01:03:24,200 --> 01:03:27,120 Speaker 1: not easy for them to manipulate the light to really 1117 01:03:27,120 --> 01:03:29,720 Speaker 1: get a handle on having a single photon. So what 1118 01:03:29,760 --> 01:03:32,000 Speaker 1: they could tell was that the human eye was very, 1119 01:03:32,160 --> 01:03:35,920 Speaker 1: very sensitive to small numbers of photons, but they couldn't 1120 01:03:35,920 --> 01:03:39,800 Speaker 1: conclusively pin it down because it's very difficult to provide 1121 01:03:39,920 --> 01:03:44,920 Speaker 1: a single photon source, one individually wrapped photon. Yeah, and 1122 01:03:45,000 --> 01:03:47,680 Speaker 1: to know that that's when the photon was there, right. 1123 01:03:47,960 --> 01:03:50,920 Speaker 1: The basic experiment you want is to shoot a photon 1124 01:03:51,000 --> 01:03:53,240 Speaker 1: at somebody's eyeball, to know that you shot the photon 1125 01:03:53,320 --> 01:03:55,400 Speaker 1: there and when you did it, and then have them 1126 01:03:55,440 --> 01:03:57,320 Speaker 1: press a button and say I saw a photon, And 1127 01:03:57,360 --> 01:04:00,320 Speaker 1: that way you can correlate the button presses with when 1128 01:04:00,320 --> 01:04:03,080 Speaker 1: the photons arrived. You could say, yeah, there are reliable 1129 01:04:03,120 --> 01:04:05,880 Speaker 1: indicators of when the photon arrives. And if they're always 1130 01:04:05,920 --> 01:04:08,200 Speaker 1: just pressing the button right, then you can tell this 1131 01:04:08,240 --> 01:04:11,560 Speaker 1: person is crazy. This it is useless. And so to 1132 01:04:11,640 --> 01:04:14,000 Speaker 1: prove that somebody could see a single photon, you need 1133 01:04:14,040 --> 01:04:17,439 Speaker 1: to know when that single photon is hitting the eye. 1134 01:04:17,480 --> 01:04:19,800 Speaker 1: That's the crucial thing. And if all you have our 1135 01:04:19,880 --> 01:04:22,280 Speaker 1: light sources that are sort of classical, like hot things 1136 01:04:22,360 --> 01:04:24,640 Speaker 1: glowing like a light bulb, you know, which has a 1137 01:04:24,720 --> 01:04:27,520 Speaker 1: tongusen filament in it which glows because it gets hot 1138 01:04:27,560 --> 01:04:30,600 Speaker 1: and shoots out of photons. It's difficult to manage because 1139 01:04:30,720 --> 01:04:32,400 Speaker 1: you can turn it down and you can make it 1140 01:04:32,560 --> 01:04:35,120 Speaker 1: very low intensity, but you don't have control over when 1141 01:04:35,120 --> 01:04:37,760 Speaker 1: the photons are admitted, so you never know, for example, 1142 01:04:37,840 --> 01:04:40,320 Speaker 1: like was that one photon that came out or two 1143 01:04:40,520 --> 01:04:42,800 Speaker 1: that Katie pressed the button? Because that was the one 1144 01:04:42,840 --> 01:04:45,280 Speaker 1: time when a couple of photons actually hit her eyeball 1145 01:04:45,320 --> 01:04:47,720 Speaker 1: and not the time when a single photon hit the eyeball. 1146 01:04:47,840 --> 01:04:50,840 Speaker 1: And so the breakthrough in these experiments actually wasn't until 1147 01:04:50,880 --> 01:04:55,360 Speaker 1: about ten years ago when people developed really crazy nonlinear 1148 01:04:55,440 --> 01:04:59,600 Speaker 1: quantum optics to separate individual photons. So is it like 1149 01:04:59,640 --> 01:05:03,960 Speaker 1: a little little gun that shoots a photon. It would 1150 01:05:04,000 --> 01:05:05,680 Speaker 1: be pretty cool to have like a button you could 1151 01:05:05,680 --> 01:05:08,520 Speaker 1: press to shoot a single photon. The key idea actually 1152 01:05:08,560 --> 01:05:11,160 Speaker 1: is to split a photon. So you have a very 1153 01:05:11,240 --> 01:05:14,240 Speaker 1: low intensity source that shoots out photons at you, and 1154 01:05:14,240 --> 01:05:15,920 Speaker 1: what you do is you pass it through a special 1155 01:05:16,080 --> 01:05:19,000 Speaker 1: kind of crystal it's called a down converter, and it 1156 01:05:19,040 --> 01:05:21,680 Speaker 1: takes a single photon and it splits it into two 1157 01:05:21,720 --> 01:05:24,400 Speaker 1: photons of less energy. Now, one you can use for 1158 01:05:24,440 --> 01:05:26,320 Speaker 1: your experiment, and the other one you can use is 1159 01:05:26,360 --> 01:05:28,800 Speaker 1: a tag that tells you, like, oh, a photon just 1160 01:05:28,920 --> 01:05:32,640 Speaker 1: came through. You can measure those using very high precision optics, 1161 01:05:32,880 --> 01:05:36,760 Speaker 1: so you know when the experiment tee is observing photons 1162 01:05:36,760 --> 01:05:38,640 Speaker 1: and when they're not, and so you can tell, oh, 1163 01:05:38,640 --> 01:05:40,840 Speaker 1: there are two photons in the experiment right now, let's 1164 01:05:40,880 --> 01:05:43,680 Speaker 1: disregard this, and you can tell when a single photon 1165 01:05:43,720 --> 01:05:46,400 Speaker 1: has arrived and no other photons have come through. So 1166 01:05:46,440 --> 01:05:49,360 Speaker 1: it's more about being able to count the photons and 1167 01:05:49,520 --> 01:05:53,120 Speaker 1: actually manipulating the photons themselves. Oh that's so interesting, yeah, 1168 01:05:53,200 --> 01:05:56,120 Speaker 1: because like if you want to detect a photon, you 1169 01:05:56,200 --> 01:05:59,720 Speaker 1: kind of have to have whatever thing detect the photon 1170 01:06:00,080 --> 01:06:03,600 Speaker 1: interact with the photon, which would not necessarily allow it 1171 01:06:03,680 --> 01:06:06,520 Speaker 1: to also reach the eye right exactly, you don't want 1172 01:06:06,520 --> 01:06:09,040 Speaker 1: to interfere with that photon which is headed towards the eyeball. 1173 01:06:09,480 --> 01:06:13,360 Speaker 1: So this crazy quantum optics, these strange crystals split it 1174 01:06:13,400 --> 01:06:16,120 Speaker 1: and give you one photon for your accounting and another 1175 01:06:16,160 --> 01:06:19,800 Speaker 1: photon for your experiment, and there of course entangled together. 1176 01:06:19,840 --> 01:06:21,680 Speaker 1: And so you know that when you see a photon, 1177 01:06:21,760 --> 01:06:24,480 Speaker 1: and your little detector that the eyeball should also have 1178 01:06:24,560 --> 01:06:27,120 Speaker 1: seen one. So then they could have people sitting there 1179 01:06:27,120 --> 01:06:29,640 Speaker 1: pressing a button and answering like, oh I saw one, No, 1180 01:06:29,720 --> 01:06:31,760 Speaker 1: I didn't see one. It's like one of those uh 1181 01:06:31,960 --> 01:06:35,000 Speaker 1: those like heart necklaces you'd get at Chuck E Cheese 1182 01:06:35,080 --> 01:06:38,320 Speaker 1: is with your best friend forever. It's like split in 1183 01:06:38,400 --> 01:06:41,320 Speaker 1: half and each one of you got one piece of 1184 01:06:41,320 --> 01:06:44,960 Speaker 1: the heart necklace. Yeah, it's just like that. In fact, 1185 01:06:45,040 --> 01:06:47,120 Speaker 1: it's called the Chuck E Cheese Experiment just for that. 1186 01:06:49,200 --> 01:06:52,280 Speaker 1: And so it's only in two sixteen that they finally 1187 01:06:52,280 --> 01:06:55,440 Speaker 1: put all of this together, this crazy experimental apparatus, and 1188 01:06:55,480 --> 01:06:59,680 Speaker 1: confirmed that the human eye can see a single photon. 1189 01:06:59,800 --> 01:07:02,120 Speaker 1: If it makes it to the retina, it will be 1190 01:07:02,160 --> 01:07:04,200 Speaker 1: able to detect it. So if you're sitting in a 1191 01:07:04,280 --> 01:07:07,040 Speaker 1: dark room and a single photon from a distant star 1192 01:07:07,200 --> 01:07:10,480 Speaker 1: HiT's your retina, you will see a flash of light. 1193 01:07:10,840 --> 01:07:14,160 Speaker 1: So in with people in this experiment, they're pressing this 1194 01:07:14,240 --> 01:07:17,720 Speaker 1: button when they're seeing a flash of light, did they 1195 01:07:17,800 --> 01:07:21,680 Speaker 1: describe like what that experience was like? Yeah, they see 1196 01:07:21,720 --> 01:07:24,600 Speaker 1: like a tiny little pinprick of light, like the smallest 1197 01:07:24,640 --> 01:07:28,200 Speaker 1: little flashlight possible. That's amazing. It is amazing, and it 1198 01:07:28,280 --> 01:07:30,880 Speaker 1: tells you like sort of the limit of your ability, 1199 01:07:31,000 --> 01:07:33,800 Speaker 1: like lights up a single pixel in your brain, so 1200 01:07:33,840 --> 01:07:35,760 Speaker 1: now you can tell like how big is one of 1201 01:07:35,800 --> 01:07:41,120 Speaker 1: your brain pixels. I think it's super cool, And people, 1202 01:07:41,160 --> 01:07:43,840 Speaker 1: of course have gone beyond that and started to ask 1203 01:07:43,960 --> 01:07:47,400 Speaker 1: questions about the quantum mechanics of it. Now we know 1204 01:07:47,520 --> 01:07:51,160 Speaker 1: the human eyeball is basically a quantum opsticks device. It 1205 01:07:51,200 --> 01:07:54,360 Speaker 1: can interact with single photons, So now we can ask 1206 01:07:54,400 --> 01:07:57,600 Speaker 1: interesting questions like what happens if we send photon to 1207 01:07:57,680 --> 01:08:01,160 Speaker 1: the eyeball that are in an undert Rman's state. You 1208 01:08:01,160 --> 01:08:04,520 Speaker 1: know that quantum mechanical objects can have like the possibility 1209 01:08:04,560 --> 01:08:07,320 Speaker 1: of being in two different locations at once. But the 1210 01:08:07,360 --> 01:08:10,160 Speaker 1: strange thing about us is that we don't observe things 1211 01:08:10,200 --> 01:08:13,560 Speaker 1: quantum mechanically. When you look at something, it's either here 1212 01:08:13,760 --> 01:08:15,720 Speaker 1: or it's there. And this is one of the deepest 1213 01:08:15,800 --> 01:08:19,280 Speaker 1: questions in quantum physics is why we can't observe things 1214 01:08:19,439 --> 01:08:22,640 Speaker 1: to be in superpositions. Why if quantum particles can have 1215 01:08:22,720 --> 01:08:25,400 Speaker 1: like probabilities to be in two different states, we only 1216 01:08:25,400 --> 01:08:27,960 Speaker 1: ever observe them to be in one so people are 1217 01:08:27,960 --> 01:08:31,519 Speaker 1: doing experiments to see can the eyeball see photons that 1218 01:08:31,520 --> 01:08:34,280 Speaker 1: are in a superposition. So they take like this single 1219 01:08:34,320 --> 01:08:38,559 Speaker 1: photon and they pass it through a half silvered mirror. 1220 01:08:38,760 --> 01:08:41,560 Speaker 1: This is a mirror which sometimes sends the photon to 1221 01:08:41,600 --> 01:08:43,880 Speaker 1: the left and sometimes sends it to the right. And 1222 01:08:43,880 --> 01:08:46,400 Speaker 1: it's a quantum mechanical thing. It's random. So now what 1223 01:08:46,479 --> 01:08:48,800 Speaker 1: happens when the photon passes through it is that, because 1224 01:08:48,800 --> 01:08:51,880 Speaker 1: it's quantum mechanical, it doesn't like actually go left or 1225 01:08:51,960 --> 01:08:54,800 Speaker 1: actually go right every time. It has a probability to 1226 01:08:54,880 --> 01:08:57,320 Speaker 1: go left and the probability to go right. This is 1227 01:08:57,320 --> 01:08:59,559 Speaker 1: sort of like the double slit experiment. So then what 1228 01:08:59,640 --> 01:09:02,400 Speaker 1: happened when it hits your eyeball is that when the 1229 01:09:02,439 --> 01:09:05,479 Speaker 1: measurement collapses in the universe says, okay, we have to 1230 01:09:05,560 --> 01:09:09,599 Speaker 1: decide which way the photon went. Or can your eye 1231 01:09:09,680 --> 01:09:13,840 Speaker 1: somehow see a quantum mechanically superimposed photon. Do you get 1232 01:09:13,880 --> 01:09:16,679 Speaker 1: like two little flashes, one on the left and one 1233 01:09:16,760 --> 01:09:19,000 Speaker 1: on the right. These are the kind of experiments people 1234 01:09:19,000 --> 01:09:22,800 Speaker 1: are doing right now. That's incredible. I love that so much. 1235 01:09:23,280 --> 01:09:27,479 Speaker 1: There's something about these kinds of experiments where you are 1236 01:09:27,920 --> 01:09:32,800 Speaker 1: seeing how we're perceiving things in the world, especially like 1237 01:09:32,840 --> 01:09:35,160 Speaker 1: on the quantum level. That it's like it kind of 1238 01:09:35,200 --> 01:09:40,000 Speaker 1: gives me chills that we can actually have that direct 1239 01:09:40,880 --> 01:09:46,559 Speaker 1: human observation of quantum physics. It is really amazing, and 1240 01:09:46,600 --> 01:09:49,760 Speaker 1: there are some fun theories of quantum mechanics that we 1241 01:09:49,880 --> 01:09:53,040 Speaker 1: might actually be able to test using this kind of scenario. 1242 01:09:53,479 --> 01:09:56,760 Speaker 1: People wonder like when does the wave function collapse? When 1243 01:09:56,800 --> 01:09:59,080 Speaker 1: does the universe decide or the photon went left or 1244 01:09:59,120 --> 01:10:01,680 Speaker 1: went right? With theories we've talked about with experts on 1245 01:10:01,720 --> 01:10:04,720 Speaker 1: this podcast, some ideas being that the universe splits and 1246 01:10:04,800 --> 01:10:07,360 Speaker 1: one goes left and one goes rights. Others that it's 1247 01:10:07,360 --> 01:10:10,840 Speaker 1: actually dependent on sensitive details of the initial conditions. But 1248 01:10:10,880 --> 01:10:14,680 Speaker 1: there are some theories called spontaneous collapse that says that 1249 01:10:14,720 --> 01:10:17,640 Speaker 1: the collapse to the side, left or right depends in 1250 01:10:17,760 --> 01:10:20,760 Speaker 1: some way on like the size of the object that 1251 01:10:20,800 --> 01:10:24,080 Speaker 1: it's interacting with, which is a little weird, and in 1252 01:10:24,120 --> 01:10:27,439 Speaker 1: that scenario, different size parts of the eye might be 1253 01:10:27,560 --> 01:10:30,639 Speaker 1: more or less likely to induce this collapse. You could 1254 01:10:30,640 --> 01:10:34,360 Speaker 1: actually test this theory by doing this experiment. So this 1255 01:10:34,400 --> 01:10:36,840 Speaker 1: is the kind of thing people are working on right now. 1256 01:10:37,320 --> 01:10:42,440 Speaker 1: Quantum eyeball experiments. That's great. So we're turning humans into 1257 01:10:42,920 --> 01:10:48,519 Speaker 1: sort of like an actual quantum detection instrument. Yeah, because 1258 01:10:48,560 --> 01:10:52,000 Speaker 1: the critical question in all of these experiments is when 1259 01:10:52,080 --> 01:10:55,160 Speaker 1: does the wave function collapse? And if you're interacting with 1260 01:10:55,200 --> 01:10:58,200 Speaker 1: a quantum object using a classical device like a finger 1261 01:10:58,640 --> 01:11:01,479 Speaker 1: or an eyeball, then has to collapse at some point. 1262 01:11:01,560 --> 01:11:03,640 Speaker 1: But the device you're interacting it with, of course, is 1263 01:11:03,680 --> 01:11:06,719 Speaker 1: made of little quantum bits. And so if your eyeball 1264 01:11:06,760 --> 01:11:09,879 Speaker 1: can stay a quantum object then interact with the quantum 1265 01:11:09,880 --> 01:11:12,880 Speaker 1: photon in a quantum way and maintain its superposition, then 1266 01:11:12,920 --> 01:11:16,680 Speaker 1: maybe your eyeball can be in a superposition of quantum states. Right, 1267 01:11:16,760 --> 01:11:19,160 Speaker 1: your eyeball can be in two probabilities, like it saw 1268 01:11:19,160 --> 01:11:20,920 Speaker 1: it on left and it's saw it on the right, 1269 01:11:21,400 --> 01:11:23,519 Speaker 1: And then how does your brain interpret that? Right? Does 1270 01:11:23,560 --> 01:11:26,439 Speaker 1: it collapse when it gets the optical nerve? We don't know. 1271 01:11:26,800 --> 01:11:29,160 Speaker 1: These are super fun questions that we'll be digging into 1272 01:11:29,240 --> 01:11:32,000 Speaker 1: probably for hundreds of years. Well, you just made me 1273 01:11:32,080 --> 01:11:36,080 Speaker 1: go cross side, all right. Well, I think we dove 1274 01:11:36,200 --> 01:11:40,320 Speaker 1: deep into Supernova Scarlet and crazy Blue on this podcast, 1275 01:11:40,439 --> 01:11:42,800 Speaker 1: and we do know now that the human eye can 1276 01:11:43,000 --> 01:11:46,479 Speaker 1: actually see a single photon, and that's going to allow 1277 01:11:46,560 --> 01:11:49,439 Speaker 1: us to probe the frontiers of quantum mechanics and understand 1278 01:11:49,479 --> 01:11:52,800 Speaker 1: crazy things about superpositions and what it's like to be 1279 01:11:52,840 --> 01:11:55,880 Speaker 1: a mantis shrimp. I just love that when I see 1280 01:11:55,920 --> 01:12:01,360 Speaker 1: a star, I'm directly kissing the protons from star with 1281 01:12:01,400 --> 01:12:04,280 Speaker 1: my eyeballs. Unfortunately, you don't have to put the whole 1282 01:12:04,320 --> 01:12:08,920 Speaker 1: star against your eyeball in order to see it. All right, Well, 1283 01:12:08,920 --> 01:12:10,640 Speaker 1: thank you very much Katie for joining us on this 1284 01:12:10,720 --> 01:12:13,800 Speaker 1: examination of the physics of the human eyeball, and thanks 1285 01:12:13,800 --> 01:12:16,240 Speaker 1: to everybody out there for listening and coming with us 1286 01:12:16,280 --> 01:12:19,840 Speaker 1: on this journey of curiosity and discovery. Thanks for having 1287 01:12:19,840 --> 01:12:30,320 Speaker 1: me tune in next time. Everyone, Thanks for listening, and 1288 01:12:30,320 --> 01:12:33,040 Speaker 1: remember that Daniel and Jorge explained. The universe is a 1289 01:12:33,120 --> 01:12:36,559 Speaker 1: production of I Heart Radio. For more podcast For my 1290 01:12:36,640 --> 01:12:40,240 Speaker 1: Heart Radio, visit the I heart Radio app, Apple Podcasts, 1291 01:12:40,360 --> 01:12:42,719 Speaker 1: or wherever you listen to your favorite shows.