WEBVTT - Compass Pathways CEO on 'Magic Mushrooms'

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<v Speaker 1>This is Bloomberg Business Week. I'm Carol Masser. Every day

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<v Speaker 1>Global News. You're listening to Bloomberg Business Week on this Tuesday.

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<v Speaker 1>I'm Carol Masser. So we talked about New York City's

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<v Speaker 1>covin I team positive test rate over seven day periods

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<v Speaker 1>staying below a threshold that would trigger shutdown of schools.

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<v Speaker 1>That's good. We did see groups representing you as doctors, nurses,

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<v Speaker 1>and hospitals urging President Trump to share information about the

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<v Speaker 1>administration's coronavirus response with President like Joe Biden and his

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<v Speaker 1>transition team. We had Germany warning and glamrkele that Germany

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<v Speaker 1>remains very serious, but there is some optimism that an

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<v Speaker 1>economic recovery will gather pace once the pandemic is brought

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<v Speaker 1>under control. There's a lot going on global cases. My meantime,

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<v Speaker 1>they're topping fifty fine point one million when it comes

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<v Speaker 1>to COVID nineteen deaths one three million. Back with us

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<v Speaker 1>for our daily virus update. Dr David Levy, the CEO

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<v Speaker 1>of the healthcare company E h E Health, and he

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<v Speaker 1>joins us on the phone in New York City. Dr. Leaving,

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<v Speaker 1>Nice to have you back with us. How are things going,

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<v Speaker 1>What are you seeing when it comes to the virus.

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<v Speaker 1>Thanks so much, Carol's great to be back. Well, you know,

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<v Speaker 1>we basically have around the rest of the country and

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<v Speaker 1>explosion of cases, and they're creeping up in New York.

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<v Speaker 1>We have some great silver linings on their horizon with

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<v Speaker 1>respect to both vaccines and the advent of antibody treatment

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<v Speaker 1>monoclonal antibody treatment. But in the meantime, from now until

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<v Speaker 1>the end of the holidays in December, we've got to

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<v Speaker 1>keep focused on what I call public health one oh

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<v Speaker 1>one masks, social distancing testing, positive contact tracing, and positive

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<v Speaker 1>people quarantine. It's as basic and as simple as that,

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<v Speaker 1>and it's the thing that's right at our hands to

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<v Speaker 1>be able to do with actively. Yeah, I mean, listen,

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<v Speaker 1>you know, we all know what it is, right, social

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<v Speaker 1>distancing and wearing masks. It gets tougher. Though. I think

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<v Speaker 1>it's fair to say that once everybody has to be inside,

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<v Speaker 1>you can't be outside like you were maybe over the summer. Correct.

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<v Speaker 1>And I also do think that there's something now that

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<v Speaker 1>we're what eight months into this, there's pandemic fatigue, and

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<v Speaker 1>I think there are people who who you know, left brain,

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<v Speaker 1>right brain. I understand this is what we need to do,

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<v Speaker 1>but I'm exhausted. I'm tired of this. Yeah, so we're

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<v Speaker 1>all exhausted. You know. We see it at our own company,

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<v Speaker 1>we see it at our clients companies, we see it everywhere.

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<v Speaker 1>And all I can tell you it's a leadership to

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<v Speaker 1>get out there and to keep on pushing people to

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<v Speaker 1>the finish line, pushing them to the finish line. We

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<v Speaker 1>will get to the end of this. I am confident

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<v Speaker 1>of that this is going to start looking much much

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<v Speaker 1>better with the turn of the year, and we just

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<v Speaker 1>have to keep on strong right up to the end.

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<v Speaker 1>And there's there's no other answer for it. Frankly, at

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<v Speaker 1>the moment, well, And it's interesting that you say that too,

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<v Speaker 1>um at a time when I just read a headline

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<v Speaker 1>kind of leading into you out doctors, nurses, hospitals urging

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<v Speaker 1>the current administration to share information about the White House's

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<v Speaker 1>coronavirus response with President elect Joe Biden's transition team. How

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<v Speaker 1>do you s someone who understands this virus in the

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<v Speaker 1>medical community, understand the frontline workers who are constantly putting

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<v Speaker 1>their lives at risk and watching these cases that are

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<v Speaker 1>you know, increasing around the country, around the world. How

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<v Speaker 1>important is it that this transition just when it comes

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<v Speaker 1>to COVID nineteen be smart, go well, and that there

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<v Speaker 1>are no laps, right, that we just kind of are

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<v Speaker 1>as seamless as possible. Well, just to give people perspective

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<v Speaker 1>on what we're looking at with respect to the advent

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<v Speaker 1>of vaccines and antibodies, you're talking about two specific treatments

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<v Speaker 1>of vaccine which creates active immunity, which have focused just

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<v Speaker 1>on the vulnerable population. And when we're looking at efficacy,

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<v Speaker 1>you're talking about bringing down the entire lethality of this

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<v Speaker 1>epidemic just probably focusing on the vulnerable population somewhere not

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<v Speaker 1>that much different than generalized influenza, and that's without her immunity.

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<v Speaker 1>It's just focusing on the vulnerable, vulnerable people. The same

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<v Speaker 1>thing with anti the same thing with MONOCOLI anybodies. This

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<v Speaker 1>is an anti viral therapy which has about a seventy

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<v Speaker 1>percent reduction in admission rates for folks who are at risk,

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<v Speaker 1>namely vulnerable populations. That can bring the case fatality, the

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<v Speaker 1>lethality of this epidemic down significantly to be just a

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<v Speaker 1>little bit above uh one and a half times a

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<v Speaker 1>general flu epidemic, or a little bit a little bit higher.

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<v Speaker 1>So the idea of getting these two new therapies, or

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<v Speaker 1>these two new strategies to vulnerable vulnerable populations relates to

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<v Speaker 1>two things. One is obviously supply, then distribution and access.

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<v Speaker 1>And if we don't have all of that seamlessly coordinated,

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<v Speaker 1>we're going to miss an enormous opportunity to significantly drop fatality. That,

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<v Speaker 1>by the way, is without getting into the whole distribution

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<v Speaker 1>of and the ramping up of testing masks and ppe,

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<v Speaker 1>which is basically back to the you know, public health

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<v Speaker 1>one on one issues. But boy, with these two new

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<v Speaker 1>therapies coming down the pike, if we are not seamlessly coordinated,

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<v Speaker 1>we can lose a major opportunity to have some serious impact. Carol.

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<v Speaker 1>If this was a baseball game, where are we in

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<v Speaker 1>terms of innings? Seven? Oh, that's positive. Yeah, well, I'm

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<v Speaker 1>I'm optimistic. I mean, there could be extra innings. So

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<v Speaker 1>and I'm not trying to be funny here, but we're

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<v Speaker 1>going to have a rough seventh and eighth. But uh,

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<v Speaker 1>and I say that to the end of December. But

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<v Speaker 1>I really believe that as these things come online, we're

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<v Speaker 1>going to see really a significant change. And and honestly,

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<v Speaker 1>I don't see how we can start enforcing some of

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<v Speaker 1>this mask ging more seriously across the country as well.

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<v Speaker 1>Should we have a mandate, Should we have a mandate

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<v Speaker 1>come down from from the typical government. There is no

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<v Speaker 1>downside in my view to a mask mandate. I'm in

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<v Speaker 1>I just if this is not rocket science. Uh, this

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<v Speaker 1>has proven you can see the numbers some people project

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<v Speaker 1>perhaps reduction and spread just by wearing masks. This should

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<v Speaker 1>be a no brainer. It's absolutely and this is not

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<v Speaker 1>economic shutdown. It's basically just putting on a mask. Uh.

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<v Speaker 1>You know, I think it's a patriotic thing to do.

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<v Speaker 1>Quite candidly, Yeah, No, no, No, I get it. It's

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<v Speaker 1>funny too. And we've all had conversations at home at

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<v Speaker 1>work about how it's just become kind of so normal

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<v Speaker 1>for so many of us. And I think if you've

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<v Speaker 1>been in one of these major cities where you've seen

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<v Speaker 1>the impact of it, it's like putting on a seatbelt

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<v Speaker 1>when you get into a car. You know, it's interesting.

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<v Speaker 1>In New York, it's not an issue. Everybody wears a mask.

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<v Speaker 1>Everybody gets it. And frankly, I think it's because of

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<v Speaker 1>the horrific spring we had and you know, one and

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<v Speaker 1>three and fifty New Yorkers died of COVID. People get that.

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<v Speaker 1>They understand that it was over ten times out of

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<v Speaker 1>nine eleven. So we wear masks, no problem, we get it.

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<v Speaker 1>I just want to talk to you a little bit

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<v Speaker 1>more about COVID nineteen, Dr Lee, because I did feel like,

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<v Speaker 1>you know, you gave us a little bit of a

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<v Speaker 1>timeline and not a little bit you gave us, you know,

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<v Speaker 1>saying we're in the seventh inning. Uh if this was

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<v Speaker 1>a baseball game, but you said the seventh and athennings

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<v Speaker 1>are going to be pretty tough. But the difference between

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<v Speaker 1>now and let's say a few months ago, perhaps are

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<v Speaker 1>at the beginning of this pandemic. Is that the vaccine

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<v Speaker 1>developments that we've made progress, Yeah, for sure, of the

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<v Speaker 1>vaccine as well as the new um anti viral medications

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<v Speaker 1>and monoclonal and polyclonal antibodies, one of which was approved

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<v Speaker 1>last week. So that's been basically a story that hasn't

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<v Speaker 1>been told enough, but it's going to be a very

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<v Speaker 1>significant impact, we believe. Why is that so important in

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<v Speaker 1>addition to the vaccines, Well, um, to have a drug

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<v Speaker 1>that you can give when you're just mildly ill or

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<v Speaker 1>moderately ill. It's kind of like an antibiotic when you

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<v Speaker 1>show up to the bacteria, when you show up to

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<v Speaker 1>the hospital for the bacteria, and the moment you get

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<v Speaker 1>a shot of penicillin and you don't have to get

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<v Speaker 1>admitted to the hospital. Well, this is kind of like

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<v Speaker 1>the same thing. It's in a few an infusion, but

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<v Speaker 1>it really takes down the chance of being admitted with

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<v Speaker 1>the serious illness. And frankly, that's exactly what President Trump

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<v Speaker 1>got from the General and exactly what Governor Christie got

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<v Speaker 1>from the from Lily. So these medications are highly effective

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<v Speaker 1>and when targeted and vulnerable populations can have a very

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<v Speaker 1>significant impact, and you have to do it early. Correct, Yeah, milder,

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<v Speaker 1>moderate symptoms and vulnerable populations. The problem with that strategy

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<v Speaker 1>isn't actually it's effectiveness, it's it's supply and distribution. Uh.

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<v Speaker 1>And we're actually probably going to see in the next

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<v Speaker 1>few weeks and months we'll see infusion centers pop up

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<v Speaker 1>all over the place, right exactly. Well, that that begs

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<v Speaker 1>to that bigger question of the supply chain, whether it's

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<v Speaker 1>the vaccine or whether it's these anti viral treatments, right. Uh,

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<v Speaker 1>these are not things. I know the vaccine makers, the

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<v Speaker 1>big farmer companies, I mean, they certainly have been working

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<v Speaker 1>towards this, they've even started manufacturing it. But this is

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<v Speaker 1>going to be huge, the logistical side of manufacturing it

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<v Speaker 1>and then getting it out, the vaccine or even these

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<v Speaker 1>viral anti viral treatments exactly. And that's back to the

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<v Speaker 1>issue why you need such close coordination between the outgoing

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<v Speaker 1>and the incoming administrations. I Mean, this thing has to

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<v Speaker 1>be seamlessly coordinated, otherwise people will die, no question. All right.

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<v Speaker 1>One thing I did want to ask you too, is

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<v Speaker 1>what are you seeing when it comes to people coming

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<v Speaker 1>in and doing some of those preventive routine treatments. Have

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<v Speaker 1>you seen an increase in people feeling more comfortable about

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<v Speaker 1>coming back to the doctor's office. Yeah, we provide preventive

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<v Speaker 1>health services around the country and what we and for

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<v Speaker 1>for large employers and for their employees and spouses and families,

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<v Speaker 1>and uh, we actually were caught by surprise how engage

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<v Speaker 1>people were once we reopened after the lockdown, because people

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<v Speaker 1>have begun to understand that that much of the co

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<v Speaker 1>more bid conditions affiliated with COVID nineteen can kill you,

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<v Speaker 1>and those are all lifestyle illnesses overweight, high blood pressure,

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<v Speaker 1>diabetes and the like. Getting those things under control have

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<v Speaker 1>meaningful impact in this pandemic, and so we strongly believe

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<v Speaker 1>that that's a great reason to get back in. People

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<v Speaker 1>are figuring out that they're not going to get COVID

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<v Speaker 1>at their local hospital or their well managed doctor's office

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<v Speaker 1>because appropriate precautions are being taken and reducing comorbidities is

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<v Speaker 1>a hugely advantageous thing to do, and it's something that

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<v Speaker 1>everybody can do today without without any big dispute on

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<v Speaker 1>whether there's going to be a good outcome doctor leaving.

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<v Speaker 1>That's a great thing to do. That I just wanted

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<v Speaker 1>because we just only have about forty seconds left here,

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<v Speaker 1>I just want to follow on that. I mean, what

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<v Speaker 1>is one thing that we could change or mandate because

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<v Speaker 1>we do know that, you know, taking care of your health, wellness, weight,

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<v Speaker 1>these are things that really impact your outcome in any

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<v Speaker 1>health situation. How do we change that? How do we

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<v Speaker 1>change the trajectory in the trend line just quickly? Well,

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<v Speaker 1>in the end, I mean, you can force people to

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<v Speaker 1>do what they don't want to do. I think that frankly,

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<v Speaker 1>educating the public about how important lifestyle is UH is

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<v Speaker 1>probably the most important thing. You know, I call it.

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<v Speaker 1>You know, COVID compress this time, your overweight, your diabetic,

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<v Speaker 1>you're hypertensive. You know you may not have tender fifteen

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<v Speaker 1>or twenty years anymore to hang around and wait till

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<v Speaker 1>those things impact your end organs, your organ You know,

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<v Speaker 1>this could hit you right away. So I think the

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<v Speaker 1>most important thing is education and awareness and getting people

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<v Speaker 1>to know and to understand that they can do something

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<v Speaker 1>about it. Yeah, it's a big issue, no doubt about it,

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<v Speaker 1>especially when you look at things like the diabetes numbers

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<v Speaker 1>in the United States. Dr Levy, Thank you so much.

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<v Speaker 1>Nice to check in with you. Dr David Levy, CEO

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<v Speaker 1>of e h E Health Training us on the phone

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<v Speaker 1>in New York City. This is Bloomberg Business Week with

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<v Speaker 1>Carol Messer from Bloomberg Radio. Well, you've watched this company's videos.

0:11:47.080 --> 0:11:49.120
<v Speaker 1>I know I've treated out several. I actually went down

0:11:49.160 --> 0:11:51.360
<v Speaker 1>a rabbit hole today watching them all over again because

0:11:51.360 --> 0:11:54.160
<v Speaker 1>I've watched Spot the Dog running Cheetah wildcast. There's also

0:11:54.200 --> 0:11:57.480
<v Speaker 1>Atlas the Dynamic Humanoid. We're talking about the cutting edge

0:11:57.520 --> 0:12:00.480
<v Speaker 1>of company that puts out those robotic x you know

0:12:00.520 --> 0:12:03.760
<v Speaker 1>who they are. We're talking about Boston Dynamics. They've really

0:12:03.840 --> 0:12:06.960
<v Speaker 1>become part of our pop culture, which is about it

0:12:07.000 --> 0:12:09.880
<v Speaker 1>looks like to enter a next chapter. Sarah McBride writes

0:12:09.880 --> 0:12:14.160
<v Speaker 1>about it for Business Week, venture capital reporter at Bloomberg News,

0:12:14.240 --> 0:12:15.840
<v Speaker 1>and she joins us on the foot in San Francisco

0:12:15.840 --> 0:12:17.800
<v Speaker 1>along with Bloomberg Business wee get to Joe Webber, Joel,

0:12:17.800 --> 0:12:20.560
<v Speaker 1>how much time do you spend watching Boston Dynamics videos?

0:12:21.480 --> 0:12:24.040
<v Speaker 1>They creeping out a little bit, so yes, that's fair.

0:12:24.840 --> 0:12:27.680
<v Speaker 1>And this is a rabbit hole or like a robot hole,

0:12:28.679 --> 0:12:31.200
<v Speaker 1>so so yeah, I mean I think. You know, these

0:12:31.880 --> 0:12:35.120
<v Speaker 1>videos of Boston Dynamics robots have been sort of Internet

0:12:35.240 --> 0:12:38.720
<v Speaker 1>sensation for basically as long as they've been making those robots,

0:12:38.720 --> 0:12:41.840
<v Speaker 1>and they can do some interesting things like climb stairs

0:12:42.000 --> 0:12:44.520
<v Speaker 1>and up and tours heavy things, and you know, and

0:12:44.720 --> 0:12:47.080
<v Speaker 1>you know in Asia you see them during the pandemic

0:12:47.120 --> 0:12:49.360
<v Speaker 1>and they sort of you know, bar constructions that people

0:12:49.400 --> 0:12:50.920
<v Speaker 1>to stay away from each other and that kind of

0:12:50.960 --> 0:12:54.760
<v Speaker 1>stuff that you know. The interesting thing that Sarah brings

0:12:54.760 --> 0:12:56.560
<v Speaker 1>out here is like you know, for all of those

0:12:56.640 --> 0:13:00.520
<v Speaker 1>great Internet videos and everything, like, yeah, there's a there's

0:13:00.320 --> 0:13:02.840
<v Speaker 1>a kind of a lack of a business model underlying it,

0:13:02.960 --> 0:13:06.080
<v Speaker 1>and that's actually led to some turmoil, not only a

0:13:06.160 --> 0:13:09.800
<v Speaker 1>Boston Dynamics and that sort of gets to the heart

0:13:09.840 --> 0:13:12.760
<v Speaker 1>of the story because Boston Dynamics in this whole division

0:13:12.840 --> 0:13:15.679
<v Speaker 1>have actually been up for sale and they might catch

0:13:15.800 --> 0:13:19.240
<v Speaker 1>some big money. Um how much money and who's buying

0:13:19.480 --> 0:13:25.160
<v Speaker 1>so well? Um, Apparently Hyundai Motor Corp. Has been talking

0:13:25.160 --> 0:13:28.640
<v Speaker 1>to Soft Bank about buying Boston Dynamics and that would

0:13:28.640 --> 0:13:33.800
<v Speaker 1>be a price tag of around a billion dollars, I'm told,

0:13:33.840 --> 0:13:36.920
<v Speaker 1>which sounds like a lot for what for many years

0:13:36.920 --> 0:13:41.360
<v Speaker 1>has just been a vanity project. But Boston Dynamics says

0:13:41.400 --> 0:13:44.280
<v Speaker 1>it's getting to the point where it's robots can do

0:13:44.520 --> 0:13:49.760
<v Speaker 1>some pretty practical things. And um Hyundai actually has a

0:13:49.800 --> 0:13:53.760
<v Speaker 1>walking car division. If you thought the Boston Dynamics videos

0:13:53.760 --> 0:13:58.360
<v Speaker 1>were terrifying, way tweet some of the walking car videos.

0:13:58.480 --> 0:14:00.760
<v Speaker 1>And so who knows. I think guy saw that movie.

0:14:00.760 --> 0:14:04.719
<v Speaker 1>It was called Transformers exactly. But it's like, but it's

0:14:04.720 --> 0:14:08.280
<v Speaker 1>amazing too. Like I had my producer, um Ario Gomi,

0:14:08.480 --> 0:14:10.880
<v Speaker 1>he like went online too because we were talking about

0:14:11.559 --> 0:14:14.880
<v Speaker 1>the robots, the robots, the humanoids that we're cheering at

0:14:14.920 --> 0:14:20.360
<v Speaker 1>a baseball game. Yeah, this summer, no human fans were allowed,

0:14:20.400 --> 0:14:24.320
<v Speaker 1>but robots fans were allowed. And Stuffink owns a ton

0:14:24.360 --> 0:14:28.440
<v Speaker 1>of robots companies, not just Boston Dynamics. So they mixed

0:14:28.560 --> 0:14:32.560
<v Speaker 1>up some spot dog robots from Boston Dynamics with some

0:14:32.640 --> 0:14:36.120
<v Speaker 1>of their others and had them cheering on the sidelines,

0:14:36.440 --> 0:14:41.840
<v Speaker 1>wearing baseball caps and singing fan songs, eating hot dogs,

0:14:41.920 --> 0:14:48.240
<v Speaker 1>having a beer. Now not so much, it's really I mean,

0:14:48.240 --> 0:14:52.240
<v Speaker 1>there are practical things that these robots can do. But

0:14:52.360 --> 0:14:56.360
<v Speaker 1>the company says it's next generation of robots which will

0:14:56.840 --> 0:15:00.320
<v Speaker 1>handle logistics and work in warehouses are the one that

0:15:00.360 --> 0:15:03.400
<v Speaker 1>are going to be super practical, and those are called

0:15:03.560 --> 0:15:06.720
<v Speaker 1>handle and do a lot of things which don't sound

0:15:06.720 --> 0:15:10.360
<v Speaker 1>that tough, like taking boxes off of trucks and loading

0:15:10.400 --> 0:15:14.280
<v Speaker 1>them onto palates, but apparently are very complicated for the

0:15:14.320 --> 0:15:17.720
<v Speaker 1>types of machines and factories to do. Now that's where

0:15:17.720 --> 0:15:24.320
<v Speaker 1>they say they'll really shine. So thing ingredients all of

0:15:24.320 --> 0:15:27.360
<v Speaker 1>this sarah um because you know, if if, if it

0:15:27.440 --> 0:15:29.920
<v Speaker 1>seems like there's actually like a potential to you know,

0:15:30.000 --> 0:15:33.280
<v Speaker 1>make money just around the corner, Um, why not stick

0:15:33.280 --> 0:15:36.200
<v Speaker 1>with that? Why? Why why would something look to moad

0:15:36.240 --> 0:15:40.880
<v Speaker 1>this now? Well, stuff think has had so many um

0:15:41.840 --> 0:15:45.880
<v Speaker 1>uh challenges and we had that big cover story last

0:15:45.960 --> 0:15:48.840
<v Speaker 1>year about some of the challenges they've been facing. We

0:15:48.960 --> 0:15:53.160
<v Speaker 1>work has imploded and uh. Then this year with COVID,

0:15:53.240 --> 0:15:55.280
<v Speaker 1>they were just in a position where they were trying

0:15:55.320 --> 0:15:58.800
<v Speaker 1>to raise cash. They sold up a lot of businesses,

0:15:58.920 --> 0:16:03.760
<v Speaker 1>including arm and so this was just one obvious place

0:16:03.800 --> 0:16:09.160
<v Speaker 1>in their portfolio where it had been um sucking money

0:16:09.240 --> 0:16:11.480
<v Speaker 1>out of soft bank. It was costing them over a

0:16:11.560 --> 0:16:14.280
<v Speaker 1>hundred and fifty million dollars a year just to run

0:16:14.400 --> 0:16:18.240
<v Speaker 1>Boston Dynamics. So this was an obvious place to make

0:16:18.280 --> 0:16:21.920
<v Speaker 1>a cut where they could uh worth mentioning there that

0:16:22.120 --> 0:16:25.360
<v Speaker 1>also ye yeah, worth mentioning there that SoftBank isn't the

0:16:25.400 --> 0:16:29.160
<v Speaker 1>only owner of that Boston Dynamics has had before before SoftBank,

0:16:29.200 --> 0:16:33.360
<v Speaker 1>who was it against? Sarah Google the same thing. Google

0:16:33.480 --> 0:16:36.560
<v Speaker 1>was perfectly prepared to have a vanity project and then

0:16:36.600 --> 0:16:40.560
<v Speaker 1>a new CFO came in started kind of putting financial

0:16:40.600 --> 0:16:43.360
<v Speaker 1>controls on different parts of the company. It was part

0:16:43.400 --> 0:16:47.320
<v Speaker 1>of Google X, that part of Google that does super

0:16:47.440 --> 0:16:52.280
<v Speaker 1>cool cutting edge projects, and she just said, nope, we

0:16:52.320 --> 0:16:55.720
<v Speaker 1>need to impose some financial discipline. So they got fuld

0:16:55.760 --> 0:16:59.720
<v Speaker 1>to soft Bank, and that was um complicated and had

0:16:59.760 --> 0:17:05.040
<v Speaker 1>to go through review by the government because Boston Dynamics

0:17:05.080 --> 0:17:09.880
<v Speaker 1>has very cutting edge technology. In fact, the military used

0:17:09.880 --> 0:17:13.119
<v Speaker 1>to pay for a lot of Boston Dynamics projects that

0:17:13.359 --> 0:17:17.040
<v Speaker 1>stopped under Google. And now if it sells again to

0:17:17.160 --> 0:17:20.920
<v Speaker 1>another non US entity, it would again have to be

0:17:21.000 --> 0:17:24.680
<v Speaker 1>reviewed by the government. So it's a complicated deal. So

0:17:24.960 --> 0:17:26.040
<v Speaker 1>one thing I want to ask you, I mean, this

0:17:26.080 --> 0:17:28.680
<v Speaker 1>is a company that's been around for almost thirty years.

0:17:28.800 --> 0:17:33.040
<v Speaker 1>I mean, and it does sell stuff, it does sell robots,

0:17:33.080 --> 0:17:37.959
<v Speaker 1>but can it be a really successful company? Uh? You know,

0:17:38.240 --> 0:17:40.960
<v Speaker 1>And and and really become something. And almost I think

0:17:41.000 --> 0:17:43.440
<v Speaker 1>you end the story saying that, you know, it's it's

0:17:43.440 --> 0:17:46.120
<v Speaker 1>an opportunity for them to kind of become the Google

0:17:46.160 --> 0:17:48.359
<v Speaker 1>of the robotics industry, or somebody has talked about it.

0:17:48.400 --> 0:17:54.560
<v Speaker 1>We really don't have necessarily someone of this ilk out there. Yeah,

0:17:54.680 --> 0:17:58.919
<v Speaker 1>robotics is a fascinating field with hundreds of startups and

0:17:59.000 --> 0:18:03.000
<v Speaker 1>so many people trying to achieve dominance in the field.

0:18:03.320 --> 0:18:08.120
<v Speaker 1>And um, they had owners who were content to let

0:18:08.160 --> 0:18:12.199
<v Speaker 1>them just spend hundreds of millions of dollars researching the

0:18:12.240 --> 0:18:16.359
<v Speaker 1>best types of robots. So arguably they are now in

0:18:16.440 --> 0:18:20.840
<v Speaker 1>this very unusual position because they had owners who for

0:18:20.880 --> 0:18:24.600
<v Speaker 1>a while didn't really care about how much money they

0:18:24.600 --> 0:18:30.200
<v Speaker 1>were spending bankrolling Boston Dynamics. But the company was profitable

0:18:30.400 --> 0:18:34.240
<v Speaker 1>in the past before Google bought it, and it was

0:18:34.359 --> 0:18:39.080
<v Speaker 1>doing more defense military work, and it says it can

0:18:39.080 --> 0:18:43.600
<v Speaker 1>be profitable again, and they certainly have the technological chops,

0:18:44.080 --> 0:18:46.399
<v Speaker 1>so it could be a really interesting new chapter in

0:18:46.440 --> 0:18:48.400
<v Speaker 1>their life. And I mean, Joe, you've got to get

0:18:48.520 --> 0:18:50.440
<v Speaker 1>I think you've got get one of these dogs. I'm

0:18:50.480 --> 0:19:03.399
<v Speaker 1>just saying already, doctor, I think they wrote expensive No, No,

0:19:03.600 --> 0:19:06.520
<v Speaker 1>you may not a robotic cat that sounds even creepier

0:19:06.560 --> 0:19:09.440
<v Speaker 1>than a real cat. Um uh, you know. The the

0:19:09.440 --> 0:19:11.440
<v Speaker 1>the The other thing that I'll just point out in

0:19:11.480 --> 0:19:15.040
<v Speaker 1>all of this is that there are other robotics companies

0:19:15.040 --> 0:19:17.560
<v Speaker 1>that I find really interesting, like for Nuke is one

0:19:17.600 --> 0:19:21.159
<v Speaker 1>in Jaman um does really like heavy equipment and stuff.

0:19:21.240 --> 0:19:23.800
<v Speaker 1>So I actually think strategically for Hondai, this is sort

0:19:23.800 --> 0:19:26.480
<v Speaker 1>of a way of picking up a piece that, um,

0:19:26.520 --> 0:19:28.199
<v Speaker 1>you know, if it's on the brink of having some

0:19:28.280 --> 0:19:31.760
<v Speaker 1>breakthrough products, it could become sort of a crown jewel

0:19:31.760 --> 0:19:34.440
<v Speaker 1>in the Hondai portfolio. It's a really great point and

0:19:34.480 --> 0:19:37.200
<v Speaker 1>a great story, um, and I highly recommend everyone check

0:19:37.200 --> 0:19:40.240
<v Speaker 1>it out at Bloomberg dot com. Sarah McBride, thank you

0:19:40.280 --> 0:19:42.399
<v Speaker 1>so much. Venture Capital reporter of Bloomberg News on the

0:19:42.400 --> 0:19:45.160
<v Speaker 1>phone in San Francisco. Jill Webber, editor of Bloomberg Business Week,

0:19:45.200 --> 0:19:49.240
<v Speaker 1>on the remote access from Brooklyn. This is Bloomberg Business

0:19:49.320 --> 0:19:53.080
<v Speaker 1>Week with kirol Master on Bloomberg Radio. So in an

0:19:53.160 --> 0:19:55.800
<v Speaker 1>upcoming edition of Bloomberg Business Week talks that we featured

0:19:55.840 --> 0:19:57.480
<v Speaker 1>in the magazine, we're gonna talk to one of this

0:19:57.560 --> 0:19:59.679
<v Speaker 1>year's successful I p O s, which is up more

0:19:59.680 --> 0:20:01.919
<v Speaker 1>than a hundred since its debut as an a d

0:20:02.040 --> 0:20:04.480
<v Speaker 1>R in the New York Stock Exchange in September. It's

0:20:04.520 --> 0:20:07.240
<v Speaker 1>the company that has patented a synthetic version of the

0:20:07.280 --> 0:20:10.280
<v Speaker 1>active ingredient in so called magic mushrooms for use in

0:20:10.320 --> 0:20:14.000
<v Speaker 1>treatment resistant depression. We're delighted to welcome to Boomberg Radio

0:20:14.000 --> 0:20:17.320
<v Speaker 1>Compass Pathways chairman, CEO and co founder George Goldsmith, who

0:20:17.359 --> 0:20:19.679
<v Speaker 1>joins us on the phone overseas in Europe. Georgie, it

0:20:19.760 --> 0:20:22.080
<v Speaker 1>is so great to have you here with us. We've

0:20:22.119 --> 0:20:24.600
<v Speaker 1>been talking about your company since it was featured in

0:20:24.600 --> 0:20:29.439
<v Speaker 1>Business Week magazine. How are you. I'm doing well, Carol,

0:20:29.520 --> 0:20:31.960
<v Speaker 1>and thank you so much for having me on. Well,

0:20:32.000 --> 0:20:33.639
<v Speaker 1>it's great. It's great to have you here, and what

0:20:33.720 --> 0:20:36.800
<v Speaker 1>a year it's been, and what a year Togo public. Um.

0:20:36.920 --> 0:20:39.160
<v Speaker 1>First of all, tell us a little bit about your

0:20:39.160 --> 0:20:42.600
<v Speaker 1>company and how you came across this, because I do

0:20:42.720 --> 0:20:47.800
<v Speaker 1>understand it's a pretty personal story. Um. Yes, it is

0:20:47.800 --> 0:20:50.600
<v Speaker 1>a personal story, and I think that in many ways,

0:20:50.680 --> 0:20:54.200
<v Speaker 1>so many interesting companies do form that way, and so

0:20:54.720 --> 0:20:58.160
<v Speaker 1>from our point of view, we had our son really

0:20:58.200 --> 0:21:01.240
<v Speaker 1>struggled with mental health issues when he went to university,

0:21:01.359 --> 0:21:04.960
<v Speaker 1>Like far too many young people do. We thought, how

0:21:05.000 --> 0:21:07.720
<v Speaker 1>hard could this be, you know, their good treatments and therapies.

0:21:07.840 --> 0:21:10.800
<v Speaker 1>Yet the more he encountered, the more difficult it was

0:21:11.320 --> 0:21:14.520
<v Speaker 1>for him to be recognizable to us with the side effects,

0:21:14.520 --> 0:21:17.800
<v Speaker 1>and it didn't really help him. So we then started

0:21:17.800 --> 0:21:20.639
<v Speaker 1>talking to lots of different people doing our own research.

0:21:20.720 --> 0:21:23.560
<v Speaker 1>My co founder in life he cuttering amount of dis

0:21:23.600 --> 0:21:26.840
<v Speaker 1>guy as a doctor, and and in her own researchers

0:21:26.920 --> 0:21:32.080
<v Speaker 1>she stumbled across psilocybin and philocybin research and we became

0:21:32.119 --> 0:21:35.560
<v Speaker 1>really intrigued by this um. The other thing that happened

0:21:35.600 --> 0:21:38.840
<v Speaker 1>simultaneously is the more people we talked about our own

0:21:39.680 --> 0:21:42.480
<v Speaker 1>challenges that we were facing, the more we heard from

0:21:42.520 --> 0:21:45.120
<v Speaker 1>others about their challenges. And these would be long term

0:21:45.200 --> 0:21:48.360
<v Speaker 1>friends who we've known for quite a while that they

0:21:48.400 --> 0:21:51.880
<v Speaker 1>never felt comfortable sharing their own challenges until we did.

0:21:52.359 --> 0:21:54.720
<v Speaker 1>And that really led us to to understand that almost

0:21:54.760 --> 0:21:58.359
<v Speaker 1>everybody has a story of you know how the current

0:21:58.400 --> 0:22:01.520
<v Speaker 1>system isn't quite helping enough people well enough, and that

0:22:01.640 --> 0:22:05.159
<v Speaker 1>really inspired us to look at this research. We solves

0:22:05.240 --> 0:22:09.080
<v Speaker 1>promise and and the issues, how do we bring it

0:22:09.119 --> 0:22:11.600
<v Speaker 1>to patients, not just bring it into the next journal

0:22:11.680 --> 0:22:16.000
<v Speaker 1>article and journal articles are critically important, but they're necessary

0:22:16.040 --> 0:22:18.520
<v Speaker 1>but not sufficient to bring this to patients, and that's

0:22:18.560 --> 0:22:21.040
<v Speaker 1>really our academic well, and I do you know, it's interesting.

0:22:21.080 --> 0:22:22.520
<v Speaker 1>I was doing some reading on this and that my

0:22:22.600 --> 0:22:26.639
<v Speaker 1>understanding is for those, you know, patients and individuals who

0:22:26.800 --> 0:22:31.240
<v Speaker 1>deal with and and suffer depression, that they're the existing

0:22:31.280 --> 0:22:34.720
<v Speaker 1>treatments only really work for about seventy patients, leaving as

0:22:34.720 --> 0:22:38.280
<v Speaker 1>many as ninety millions still struggling around the world. I

0:22:38.280 --> 0:22:41.160
<v Speaker 1>think that's some world health organization. So it is a

0:22:41.240 --> 0:22:43.160
<v Speaker 1>huge and I hate to put it in business terms,

0:22:43.160 --> 0:22:47.199
<v Speaker 1>but we are Bloomberg. It's a huge market. It is

0:22:47.640 --> 0:22:52.760
<v Speaker 1>give meat markets of suffering, forgive me in that sense.

0:22:52.880 --> 0:22:56.280
<v Speaker 1>And so there's a tremendous amount of suffering and I

0:22:56.320 --> 0:22:59.840
<v Speaker 1>think we've been pretty good at developing tools to ameliorate

0:23:00.000 --> 0:23:04.520
<v Speaker 1>sent of that, but is quite quite difficult because what

0:23:04.640 --> 0:23:07.800
<v Speaker 1>happens is with each new treatment, those people actually have

0:23:08.000 --> 0:23:10.359
<v Speaker 1>less and less likely to be helped by what's next.

0:23:10.359 --> 0:23:12.440
<v Speaker 1>So there's been a very large studies in the US

0:23:12.480 --> 0:23:15.560
<v Speaker 1>by the National SUDA Mental Health, and we really have

0:23:15.760 --> 0:23:19.639
<v Speaker 1>documentation for that. So if we have the opportunity to

0:23:19.720 --> 0:23:23.960
<v Speaker 1>do something unique here, which is a well dose. So

0:23:24.000 --> 0:23:27.040
<v Speaker 1>what we do is we provide a very high dose

0:23:27.119 --> 0:23:31.000
<v Speaker 1>of suicide in a carefully controlled setting under supervision by

0:23:31.160 --> 0:23:34.640
<v Speaker 1>especially trained therapists. So this isn't anything that anyone would

0:23:34.640 --> 0:23:39.240
<v Speaker 1>do at home and um patients listen to a special

0:23:39.320 --> 0:23:43.879
<v Speaker 1>soundtrack and they're really supported through this process. And what

0:23:44.040 --> 0:23:48.280
<v Speaker 1>happens is that afterwards, for many patients they experience an

0:23:48.280 --> 0:23:53.639
<v Speaker 1>immediate reduction and depression that actually lasts for quite a while.

0:23:54.160 --> 0:23:56.800
<v Speaker 1>And what are research really looking at is well, who

0:23:56.960 --> 0:24:01.919
<v Speaker 1>benefits not everyone, so who doesn't? And what separates the

0:24:01.960 --> 0:24:04.280
<v Speaker 1>people who benefit for a few weeks from the single

0:24:04.359 --> 0:24:07.159
<v Speaker 1>dose for a few months of people who actually have

0:24:07.359 --> 0:24:11.359
<v Speaker 1>even longer experiences. So we've went to the FDA and

0:24:11.400 --> 0:24:15.120
<v Speaker 1>actually we're operating now in ten countries doing clinical research

0:24:15.240 --> 0:24:19.800
<v Speaker 1>twenty one research sites, and we're really looking at how

0:24:19.800 --> 0:24:25.040
<v Speaker 1>do we do the real deep research to generate the

0:24:25.080 --> 0:24:27.600
<v Speaker 1>information and insight we need to go to what's the

0:24:27.640 --> 0:24:29.920
<v Speaker 1>next phase for us, which would be phase three trials

0:24:30.440 --> 0:24:32.760
<v Speaker 1>and we'll be putting out on our Phase two trials

0:24:32.800 --> 0:24:35.640
<v Speaker 1>about a year from now. So we've been really excited

0:24:35.640 --> 0:24:38.080
<v Speaker 1>about the progress. And I should say that the FDA

0:24:38.200 --> 0:24:42.399
<v Speaker 1>has named your experimental treatment quote a breakthrough therapy, which is,

0:24:42.960 --> 0:24:45.800
<v Speaker 1>you know, really wonderful to kind of get that acknowledgement,

0:24:45.880 --> 0:24:47.880
<v Speaker 1>but it also means now you've got to do more rigorous,

0:24:47.920 --> 0:24:51.320
<v Speaker 1>more risk adverse testing. It's a lot of pressure, I'm assuming,

0:24:51.400 --> 0:24:52.919
<v Speaker 1>and you've got to make sure you're working with the

0:24:53.000 --> 0:24:58.240
<v Speaker 1>right scientists, the best scientists, the best clinical trials correct well,

0:24:58.280 --> 0:25:02.480
<v Speaker 1>absolutely and absolutely and then even more so right because

0:25:02.880 --> 0:25:06.760
<v Speaker 1>obviously there's a history here um as what we're looking

0:25:06.800 --> 0:25:10.400
<v Speaker 1>to do is the highest quality, rigorous, most rigorous research.

0:25:10.680 --> 0:25:13.520
<v Speaker 1>The first support of Call for us was actually even

0:25:13.560 --> 0:25:16.600
<v Speaker 1>before we formed the company, to speak with regulators players

0:25:17.240 --> 0:25:19.639
<v Speaker 1>just to understand what did they think about this and

0:25:19.760 --> 0:25:22.600
<v Speaker 1>what we were really struck by in all the conversations,

0:25:22.600 --> 0:25:25.600
<v Speaker 1>and the breakthrough therapy designation is I think a perfect

0:25:25.640 --> 0:25:29.200
<v Speaker 1>example of this. The problem is so big, and that's

0:25:29.240 --> 0:25:31.840
<v Speaker 1>what you said, you know, there's such a huge amount

0:25:31.880 --> 0:25:34.679
<v Speaker 1>of suffering here. The tools we have are good for some,

0:25:34.800 --> 0:25:38.960
<v Speaker 1>but not enough. They saw that this is the promising

0:25:39.119 --> 0:25:42.360
<v Speaker 1>So what we found is that a huge amount of support,

0:25:42.400 --> 0:25:44.439
<v Speaker 1>but we really have to get this right. We have

0:25:44.480 --> 0:25:46.560
<v Speaker 1>to get it right for patients, for their families and

0:25:46.640 --> 0:25:48.720
<v Speaker 1>society just got about a minute, and then I've got

0:25:48.720 --> 0:25:49.960
<v Speaker 1>to do some news and then we'll come back. But

0:25:50.080 --> 0:25:52.159
<v Speaker 1>how big of a market opportunity do you think is

0:25:52.200 --> 0:25:57.359
<v Speaker 1>there for compass pathways? Just quickly, well, I think that

0:25:57.440 --> 0:26:00.600
<v Speaker 1>what we see in this is not obviously about ninety

0:26:00.680 --> 0:26:04.320
<v Speaker 1>million people suffering from so called treatment resistent depression. But

0:26:04.440 --> 0:26:06.960
<v Speaker 1>to be clear, this isn't people who is not a

0:26:06.960 --> 0:26:09.760
<v Speaker 1>group of people who are resisting treatment. This is a

0:26:09.760 --> 0:26:12.840
<v Speaker 1>group of people for whom are treatment stoke work. And

0:26:12.920 --> 0:26:16.359
<v Speaker 1>so perhaps you know, I think this is really really important,

0:26:16.640 --> 0:26:20.040
<v Speaker 1>but that's just the start, because really what we're looking

0:26:20.080 --> 0:26:24.200
<v Speaker 1>at is working on areas of mental health where people

0:26:24.240 --> 0:26:27.639
<v Speaker 1>get caught in patterns of negative thinking or patterns of

0:26:27.680 --> 0:26:31.240
<v Speaker 1>obsessive thinking that happens in other areas like anxiety or

0:26:31.280 --> 0:26:34.440
<v Speaker 1>O c D or other things. And we're really curious

0:26:34.480 --> 0:26:38.520
<v Speaker 1>about how could this mechanism of a high dose of

0:26:38.560 --> 0:26:42.959
<v Speaker 1>psilocybin therapy yield benefit for other classes of people who

0:26:43.000 --> 0:26:45.359
<v Speaker 1>aren't helped enough. So is this like a potentially a

0:26:45.440 --> 0:26:49.639
<v Speaker 1>multibillion dollar drug potential Just quickly, just got about fifteen

0:26:49.640 --> 0:26:54.679
<v Speaker 1>seconds here. Um, well, I think that it is potential

0:26:54.800 --> 0:26:57.159
<v Speaker 1>to have it be a therapy it's really important that

0:26:57.240 --> 0:26:59.840
<v Speaker 1>it's not a drug. It's drugs. It's given in cons

0:27:00.640 --> 0:27:05.600
<v Speaker 1>combination with psychological support, and that's the critical pick. Hey.

0:27:05.680 --> 0:27:07.439
<v Speaker 1>So before I move on, though, you did say and

0:27:07.480 --> 0:27:09.600
<v Speaker 1>I thought this was a really important distinction, George, as

0:27:09.600 --> 0:27:11.760
<v Speaker 1>you said, it's not a drug, it's a potential therapy.

0:27:12.160 --> 0:27:14.879
<v Speaker 1>Having said that, I do think you know our listeners

0:27:14.880 --> 0:27:19.160
<v Speaker 1>are curious, UM about how big that market size might

0:27:19.160 --> 0:27:22.399
<v Speaker 1>be anxiety disorders, to press it, the depression treatment market,

0:27:22.480 --> 0:27:27.800
<v Speaker 1>it's expected to be something like So what's your expectation

0:27:27.920 --> 0:27:32.159
<v Speaker 1>or thoughts on this. So a few things. One is

0:27:32.440 --> 0:27:35.840
<v Speaker 1>I appreciate your digging into this. So just to give

0:27:35.880 --> 0:27:40.040
<v Speaker 1>you some and your listeners some perspective. Depression is the

0:27:40.119 --> 0:27:45.600
<v Speaker 1>leading cause of disability worldwide, just depression, UM, and in

0:27:45.680 --> 0:27:48.840
<v Speaker 1>the US, the annual cost of depression is forecast to

0:27:48.880 --> 0:27:52.560
<v Speaker 1>be about two hundred billion per year and a large

0:27:52.640 --> 0:27:55.760
<v Speaker 1>number of out is direct costs of outpatients in patient

0:27:55.840 --> 0:27:59.719
<v Speaker 1>medical services, pharmaceutical services, and the number you've referred to

0:27:59.880 --> 0:28:04.080
<v Speaker 1>is largely in the pharmaceutical space. Now, what we know

0:28:04.280 --> 0:28:06.800
<v Speaker 1>is that about a third of patients, as you mentioned,

0:28:06.840 --> 0:28:09.639
<v Speaker 1>simply aren't helped and the third of patients that aren't

0:28:09.680 --> 0:28:13.240
<v Speaker 1>helped actually are about three or four times more expensive

0:28:13.320 --> 0:28:15.400
<v Speaker 1>two or three depends on the kind of where where

0:28:15.400 --> 0:28:18.480
<v Speaker 1>you're doing the data. UM. Then patients who are helped

0:28:18.480 --> 0:28:21.680
<v Speaker 1>by these medicines UM And so we have not only

0:28:21.880 --> 0:28:24.439
<v Speaker 1>a very large group of patients who aren't helped, but

0:28:24.600 --> 0:28:28.080
<v Speaker 1>also those are the most expensive patients. And so if

0:28:28.119 --> 0:28:30.120
<v Speaker 1>we could make a difference in their lives, I think

0:28:30.119 --> 0:28:34.680
<v Speaker 1>there's a huge opportunity to really um develop a new

0:28:34.720 --> 0:28:36.800
<v Speaker 1>model of care for them. And this is what's so

0:28:37.000 --> 0:28:39.800
<v Speaker 1>interesting about what we're doing. It is a therapy, right,

0:28:39.880 --> 0:28:45.480
<v Speaker 1>It's a single dose under supervised circumstances, with preparation and

0:28:45.520 --> 0:28:49.080
<v Speaker 1>then some follow up afterwards. And what's really unique about this.

0:28:49.160 --> 0:28:52.040
<v Speaker 1>So they did some really fascinating work at Johns Hopkins

0:28:52.040 --> 0:28:55.600
<v Speaker 1>where a lot of this research was reborn in the

0:28:56.240 --> 0:28:59.240
<v Speaker 1>over ten years ago. One of the questions they asked

0:28:59.320 --> 0:29:01.520
<v Speaker 1>patients who going through this, and they asked this question

0:29:01.640 --> 0:29:05.680
<v Speaker 1>six weeks after this experience, They said, how meaningful would

0:29:05.680 --> 0:29:09.200
<v Speaker 1>you say this experience was in your life? Personally meaningful?

0:29:09.960 --> 0:29:13.480
<v Speaker 1>And people were given, you know, sort the most meaningful

0:29:13.520 --> 0:29:17.280
<v Speaker 1>of the top five, you know, and so over seventy

0:29:18.080 --> 0:29:21.120
<v Speaker 1>the single experience was one of the top five most

0:29:21.240 --> 0:29:24.320
<v Speaker 1>meaningful experiences of their life. Right, So you can't you

0:29:24.360 --> 0:29:28.719
<v Speaker 1>can't really put you can't you can't write no, no, no.

0:29:28.800 --> 0:29:30.920
<v Speaker 1>And I wish you we were in person because you

0:29:30.920 --> 0:29:32.720
<v Speaker 1>can see me smiling, because you can't put a value

0:29:32.800 --> 0:29:35.280
<v Speaker 1>on it. And I have a sister who works in

0:29:35.280 --> 0:29:37.920
<v Speaker 1>this area, so I've kind of grown up learning about this,

0:29:38.120 --> 0:29:41.520
<v Speaker 1>and I agree that there's an unbelievable cost by not,

0:29:41.800 --> 0:29:44.480
<v Speaker 1>you know, helping out this sector of our population. And

0:29:44.520 --> 0:29:47.480
<v Speaker 1>also it's invaluable in terms of they basically get their

0:29:47.480 --> 0:29:50.320
<v Speaker 1>lives back. Having said that, you kind of evaded my answer.

0:29:50.640 --> 0:29:54.280
<v Speaker 1>So it was this like a multibillion dollar potential treatment

0:29:54.600 --> 0:29:58.680
<v Speaker 1>or tens of Yes, so I think it is multi

0:29:58.720 --> 0:30:03.120
<v Speaker 1>billion ye, And you know we've had so But again

0:30:03.680 --> 0:30:08.720
<v Speaker 1>that's if the trials work. Well, what's let's let's talk

0:30:08.760 --> 0:30:10.760
<v Speaker 1>about that, because that's a big deal. I mean, listen,

0:30:10.760 --> 0:30:13.440
<v Speaker 1>we're all learning about the drug process, right because of

0:30:13.480 --> 0:30:16.840
<v Speaker 1>the drug approval process, because of COVID. What challenges does

0:30:17.080 --> 0:30:20.760
<v Speaker 1>does the US present, What regulatory hurdles still remain? And

0:30:20.920 --> 0:30:22.960
<v Speaker 1>I do wonder if you're following kind of the playbook

0:30:23.000 --> 0:30:26.680
<v Speaker 1>from marijuana kind of prescription first. Recreational second, how are

0:30:26.720 --> 0:30:30.040
<v Speaker 1>you thinking about it? Not at all. Now, We're really

0:30:30.080 --> 0:30:34.320
<v Speaker 1>thinking about the huge unmet needs there is for patients, uh,

0:30:34.320 --> 0:30:38.800
<v Speaker 1>and that's you know, what we're really focused on is access,

0:30:38.840 --> 0:30:43.960
<v Speaker 1>and that means approval by medicaid, by you know, insurers.

0:30:43.960 --> 0:30:46.800
<v Speaker 1>So from day one, we've been really focusing on making

0:30:46.840 --> 0:30:50.080
<v Speaker 1>sure that if this in fact is successful in trials,

0:30:50.120 --> 0:30:53.160
<v Speaker 1>people have access to it, and that means working with

0:30:53.280 --> 0:30:56.040
<v Speaker 1>insurers even in the design of clinical trials to make

0:30:56.040 --> 0:31:00.320
<v Speaker 1>sure they have the evidence. Hey, this for this patient popuation.

0:31:00.480 --> 0:31:03.640
<v Speaker 1>So that's super important to us. It's a different model

0:31:03.680 --> 0:31:05.959
<v Speaker 1>than a recreational model. You're gonna have to come back

0:31:06.000 --> 0:31:07.200
<v Speaker 1>because I want to talk more. We still have a

0:31:07.280 --> 0:31:09.040
<v Speaker 1>few minutes, but I just want to squeeze in some things.

0:31:09.320 --> 0:31:11.600
<v Speaker 1>When when did you recognize the potential in this space?

0:31:11.760 --> 0:31:13.200
<v Speaker 1>Was it after your son or was it when you

0:31:13.240 --> 0:31:15.360
<v Speaker 1>started doing some digging, Like what was the thing that

0:31:15.400 --> 0:31:19.200
<v Speaker 1>you just said kind of the aha moment? Well, the

0:31:19.240 --> 0:31:24.480
<v Speaker 1>aha moment was being awakened in February by coach and

0:31:24.520 --> 0:31:27.080
<v Speaker 1>my wife who was busy doing medical research and her

0:31:27.080 --> 0:31:30.760
<v Speaker 1>sleepless night as a doctor, and she said, I came

0:31:30.800 --> 0:31:35.760
<v Speaker 1>across this thing called philocybin um. It's the active ingredient

0:31:35.920 --> 0:31:38.320
<v Speaker 1>magic mushrooms you can wear in the sixties and seventies.

0:31:38.320 --> 0:31:41.440
<v Speaker 1>What do you think of that? So say, what, honey,

0:31:42.000 --> 0:31:46.960
<v Speaker 1>finding this And you know, obviously I grown up in

0:31:47.000 --> 0:31:49.640
<v Speaker 1>that time, so I was familiar with these things, but

0:31:49.800 --> 0:31:52.560
<v Speaker 1>it was just a whole world that I had completely

0:31:52.600 --> 0:31:55.920
<v Speaker 1>forgotten about from that time. So listen, just got about

0:31:55.960 --> 0:32:00.040
<v Speaker 1>forty five seconds left here. Why synthetic um psilocybin in

0:32:00.400 --> 0:32:02.600
<v Speaker 1>And I'm just curious how you produce it? And just

0:32:02.680 --> 0:32:06.719
<v Speaker 1>quickly yeah, sorry, we need to It's a medicine, so

0:32:06.720 --> 0:32:09.320
<v Speaker 1>we need to know exactly what patients are receiving, what

0:32:09.440 --> 0:32:11.800
<v Speaker 1>the doses. It has to be the same quality every

0:32:11.800 --> 0:32:14.280
<v Speaker 1>place on the planet that it's given. So that's why

0:32:14.320 --> 0:32:16.959
<v Speaker 1>you have to use synthetic. It's the regulatory path forward.

0:32:17.480 --> 0:32:20.040
<v Speaker 1>It's one where we always know there are no impurities,

0:32:20.120 --> 0:32:23.080
<v Speaker 1>that people get exactly what it says on the tent,

0:32:23.480 --> 0:32:26.360
<v Speaker 1>and then we can do controlled research. So it's super

0:32:26.400 --> 0:32:30.680
<v Speaker 1>important that in a medical setting we use synthesize pilotype

0:32:30.680 --> 0:32:33.120
<v Speaker 1>and that's something that we've spent a lot of time

0:32:33.160 --> 0:32:35.720
<v Speaker 1>developing and working with the regulators on both sides of

0:32:35.760 --> 0:32:38.280
<v Speaker 1>the Atlantic, to make sure it's the highest purity and

0:32:38.400 --> 0:32:41.800
<v Speaker 1>genuinely a medicine with evidence. Well, just then the difference

0:32:41.840 --> 0:32:45.680
<v Speaker 1>between a drug and and a medicine is evidence. And

0:32:45.800 --> 0:32:49.840
<v Speaker 1>so we're creating a medicine from this which is philocide

0:32:49.840 --> 0:32:53.600
<v Speaker 1>and our proprietary form of right. And then with the

0:32:53.680 --> 0:32:57.320
<v Speaker 1>evidence that works. Got it, George, we have to go.

0:32:57.600 --> 0:33:00.360
<v Speaker 1>Please come back. I'd love to learn more, George old Smith,

0:33:00.400 --> 0:33:03.360
<v Speaker 1>and also listen to more of the trial, the trials George,

0:33:03.360 --> 0:33:11.040
<v Speaker 1>of course of compass pathways ro Marco journal. Now, but

0:33:11.160 --> 0:33:16.000
<v Speaker 1>you let me drive. No, no, no no home, honey, please,

0:33:16.120 --> 0:33:22.800
<v Speaker 1>I'll do the right drivel. I want to drive, just drive.

0:33:25.800 --> 0:33:36.040
<v Speaker 1>It's the questions trying. This is the drive to the globe.

0:33:36.800 --> 0:33:40.360
<v Speaker 1>Give me thanks, We'll try us down on Bluebird Radio.

0:33:40.640 --> 0:33:42.840
<v Speaker 1>It is time for the drive to the clothes on

0:33:42.840 --> 0:33:45.040
<v Speaker 1>this Tuesday, back with us as annimal Letty, head of

0:33:45.040 --> 0:33:48.360
<v Speaker 1>active Equity at Wells Fargo Asset Management. They've got roughly

0:33:48.400 --> 0:33:52.240
<v Speaker 1>six hundred seven billion dollars in assets under management, and

0:33:52.400 --> 0:33:55.360
<v Speaker 1>is back with us on the phone from Milwaukee, Wisconsin. Hey, An,

0:33:55.520 --> 0:33:57.719
<v Speaker 1>good to have you here with us. Um, how's it

0:33:57.760 --> 0:34:03.920
<v Speaker 1>going and getting cold? Carol darn winter, I know, right,

0:34:04.040 --> 0:34:06.600
<v Speaker 1>how did that happen? It's kind of dark almost already

0:34:06.640 --> 0:34:10.000
<v Speaker 1>here in New York. How are you guys doing though, Uh?

0:34:10.120 --> 0:34:13.600
<v Speaker 1>With the virus? I know at Midwestern and parts of

0:34:13.600 --> 0:34:16.640
<v Speaker 1>the country, it's been pretty tough. It has been a

0:34:16.640 --> 0:34:20.520
<v Speaker 1>little bit tougher here. Clearly the weather changing has had

0:34:20.560 --> 0:34:23.480
<v Speaker 1>an impact, but so far most of us are staying

0:34:23.760 --> 0:34:26.600
<v Speaker 1>strong and healthy and we're trying to do that the

0:34:26.600 --> 0:34:28.919
<v Speaker 1>best we can with its cold weather. Well, I'm glad

0:34:28.960 --> 0:34:31.480
<v Speaker 1>to hear that that you guys are doing okay. Um.

0:34:31.520 --> 0:34:34.080
<v Speaker 1>Having said that, I do wonder if at all your

0:34:34.120 --> 0:34:37.600
<v Speaker 1>market outlook, your market sentiment has changed at all, Considering

0:34:38.040 --> 0:34:39.799
<v Speaker 1>here we are in the last week and a half,

0:34:39.880 --> 0:34:42.400
<v Speaker 1>we've had a big development from Fiser, a big development

0:34:42.440 --> 0:34:46.399
<v Speaker 1>from Maderna, and um, my last guest at the top

0:34:46.440 --> 0:34:50.600
<v Speaker 1>of our show, UH talked about the medical world and

0:34:50.640 --> 0:34:53.000
<v Speaker 1>saying that we're kind of in the maybe seventh inning

0:34:53.480 --> 0:34:56.480
<v Speaker 1>when it comes to the virus, but the seventh and

0:34:56.520 --> 0:34:59.719
<v Speaker 1>eighth innings they're going to be really rough. UM. I

0:34:59.840 --> 0:35:03.359
<v Speaker 1>just wonder how all of this may be impacts your

0:35:03.400 --> 0:35:07.480
<v Speaker 1>visibility when it comes to investing. Yeah, it's a really

0:35:07.560 --> 0:35:10.480
<v Speaker 1>good question, because I do think we've we've gotten some

0:35:10.560 --> 0:35:13.080
<v Speaker 1>of the best news we could have gotten all year

0:35:13.360 --> 0:35:17.440
<v Speaker 1>with the fisor FISER and Maderna news. But we do

0:35:17.560 --> 0:35:21.760
<v Speaker 1>have this little bit of time now where we're waiting

0:35:21.800 --> 0:35:24.560
<v Speaker 1>for the vaccine, and so it does feel like there's

0:35:24.600 --> 0:35:27.359
<v Speaker 1>a chance that we could have an air pocket in

0:35:27.400 --> 0:35:31.319
<v Speaker 1>the both in the economy and in the market as

0:35:31.440 --> 0:35:36.040
<v Speaker 1>we're waiting for the vaccines to get distributed. And you know,

0:35:36.120 --> 0:35:40.920
<v Speaker 1>we do see that more UM states are starting the

0:35:40.920 --> 0:35:45.040
<v Speaker 1>shutdowns again. We have businesses clothing again, and so that

0:35:45.160 --> 0:35:49.520
<v Speaker 1>has a real impact and certainly more people getting sick UM.

0:35:49.840 --> 0:35:51.440
<v Speaker 1>I think we're going to see the effects of that

0:35:51.520 --> 0:35:53.600
<v Speaker 1>play out into the market. But as we both know,

0:35:53.920 --> 0:35:56.799
<v Speaker 1>the market is focused on the long term and on

0:35:56.840 --> 0:36:00.400
<v Speaker 1>the recovery, and we have seen a pretty sharp workcovery

0:36:00.520 --> 0:36:05.440
<v Speaker 1>so far. And you know, if you get the vaccine

0:36:05.640 --> 0:36:12.080
<v Speaker 1>out in masses by spring, that recovery can really continue.

0:36:12.480 --> 0:36:14.200
<v Speaker 1>And I think the economy is going to be in

0:36:14.320 --> 0:36:18.840
<v Speaker 1>really good shape and certainly will have easy comparisons. And

0:36:18.960 --> 0:36:21.360
<v Speaker 1>that's why I think you see the majority of strength

0:36:21.840 --> 0:36:24.520
<v Speaker 1>Well yeah, right, I mean, to some extent, we start

0:36:24.560 --> 0:36:27.000
<v Speaker 1>to have a little bit of visibility. So at this point,

0:36:27.040 --> 0:36:29.719
<v Speaker 1>you know, we've talked a lot about market rotation, We've

0:36:29.760 --> 0:36:33.000
<v Speaker 1>talked about the value names again, I mean, are those

0:36:33.040 --> 0:36:36.200
<v Speaker 1>parts of the market that you're interested in looking at

0:36:36.280 --> 0:36:41.880
<v Speaker 1>think investors should be considering. Certainly, our managers were paying

0:36:42.000 --> 0:36:45.439
<v Speaker 1>close attention to the cyclical of recovery very early on,

0:36:46.080 --> 0:36:48.839
<v Speaker 1>and as you said, Carol, we've seen some of that

0:36:48.880 --> 0:36:52.520
<v Speaker 1>play out. We saw the gap between growth and value,

0:36:53.440 --> 0:36:57.480
<v Speaker 1>you know, a historic gap start to narrow, and now

0:36:57.560 --> 0:37:00.560
<v Speaker 1>I think we're on more of a level playing field. Certainly,

0:37:00.640 --> 0:37:05.600
<v Speaker 1>technology is trading at a premium, but it's demanding that

0:37:05.680 --> 0:37:09.640
<v Speaker 1>premium because it's providing growth in a world that where

0:37:09.680 --> 0:37:13.880
<v Speaker 1>growth is still scarce, but value and thick local docs

0:37:14.640 --> 0:37:17.759
<v Speaker 1>there still is. There still are a lot of attractive

0:37:17.840 --> 0:37:21.799
<v Speaker 1>names there. But you have to be choosy. And the

0:37:21.840 --> 0:37:25.160
<v Speaker 1>reason why I say that is you want to avoid

0:37:25.200 --> 0:37:29.000
<v Speaker 1>companies that have weak balance sheets. Um certainly companies that

0:37:29.080 --> 0:37:33.920
<v Speaker 1>are not well competitively positioned, because the economy is rapidly

0:37:34.000 --> 0:37:38.960
<v Speaker 1>changing and we're seeing that through this pandemic. The economy

0:37:39.040 --> 0:37:44.040
<v Speaker 1>has shifted more to digitalization and almost in every aspect

0:37:44.400 --> 0:37:48.279
<v Speaker 1>in our lives, even within manufacturing, and so companies need

0:37:48.320 --> 0:37:51.920
<v Speaker 1>to be able to invest in the future and to

0:37:52.000 --> 0:37:55.319
<v Speaker 1>stay alive, quite honestly, and remain competitive. And so that's

0:37:55.360 --> 0:37:58.000
<v Speaker 1>really what our managers are focused on. There's an intense

0:37:58.080 --> 0:38:02.280
<v Speaker 1>boos once sheet on cash flows, and management are capable

0:38:02.320 --> 0:38:05.040
<v Speaker 1>of leaving their companies. You know what's interesting to Anne

0:38:05.040 --> 0:38:07.080
<v Speaker 1>and I think about this. I've thought about this a lot.

0:38:07.160 --> 0:38:10.279
<v Speaker 1>You know, after the financial crisis, that there was a

0:38:10.320 --> 0:38:12.680
<v Speaker 1>point where you looked at a city group at a

0:38:12.719 --> 0:38:15.680
<v Speaker 1>dollar a share and you knew, okay, especially after we

0:38:15.719 --> 0:38:18.840
<v Speaker 1>got through what happened to Lehman and we saw other companies,

0:38:18.880 --> 0:38:21.320
<v Speaker 1>we saw at some point that no matter what the government,

0:38:21.520 --> 0:38:24.640
<v Speaker 1>the Federal Reserve like, there were going to be a

0:38:24.680 --> 0:38:27.040
<v Speaker 1>safety net to protect these companies, right because we couldn't

0:38:27.080 --> 0:38:29.360
<v Speaker 1>let everything come undone. And I do feel like there's

0:38:29.920 --> 0:38:32.080
<v Speaker 1>it's not the same. It's not apples to apples, this

0:38:32.160 --> 0:38:36.239
<v Speaker 1>isn't a financial crisis. But nonetheless, at some point, you know,

0:38:36.280 --> 0:38:38.880
<v Speaker 1>we see it with central banks, global central banks, we

0:38:38.920 --> 0:38:40.600
<v Speaker 1>see it with the US Central Bank, we see it

0:38:40.600 --> 0:38:42.399
<v Speaker 1>even with policymakers, and we'll see if we get another

0:38:42.440 --> 0:38:45.040
<v Speaker 1>round of stimulus. But there is some understanding that we

0:38:45.120 --> 0:38:50.839
<v Speaker 1>can't let everything come undone on Main Street or Wall Street. Right,

0:38:51.520 --> 0:38:53.759
<v Speaker 1>you're absolutely right about that. I think we all know

0:38:54.200 --> 0:38:58.840
<v Speaker 1>the airlines can't all go bankrupt. We can't have every

0:38:58.880 --> 0:39:02.920
<v Speaker 1>industry at you know, certain parts of every industry at risk.

0:39:03.520 --> 0:39:07.480
<v Speaker 1>And there certainly are you know, restaurants, hotels, that travel

0:39:07.520 --> 0:39:11.319
<v Speaker 1>and leisure sector that really hasn't been able to come

0:39:11.360 --> 0:39:16.440
<v Speaker 1>back in any strong way. Um certainly has been challenged.

0:39:16.480 --> 0:39:19.160
<v Speaker 1>And so I think you'll see some stimulus go towards

0:39:19.520 --> 0:39:23.120
<v Speaker 1>those businesses and certainly hopefully to the small businesses that

0:39:23.239 --> 0:39:26.480
<v Speaker 1>really has had to bear the brunt of this pandemic.

0:39:27.680 --> 0:39:29.839
<v Speaker 1>So where don't you want to be right now? Where

0:39:29.840 --> 0:39:32.400
<v Speaker 1>would you just say, Hey, you're sitting now down with

0:39:32.440 --> 0:39:34.960
<v Speaker 1>your best friends, You're having a glass of wine, and

0:39:35.000 --> 0:39:39.320
<v Speaker 1>you're saying, I don't even think about it. I think

0:39:39.560 --> 0:39:44.799
<v Speaker 1>the areas that a lot of our managers are underweight

0:39:45.280 --> 0:39:47.040
<v Speaker 1>the index and you could be having a glass of water.

0:39:47.239 --> 0:39:48.720
<v Speaker 1>You don't have to drink, you don't have to have alcohol.

0:39:48.719 --> 0:39:50.400
<v Speaker 1>I'm just gonna put that out there. Forgive me. I

0:39:50.440 --> 0:39:54.000
<v Speaker 1>think people think I'm a whine Oh I'm not. I

0:39:54.200 --> 0:39:58.040
<v Speaker 1>think all of us, probably you know, diffen a little bit.

0:39:59.600 --> 0:40:02.839
<v Speaker 1>It's been rough. You know, I would say that, you know,

0:40:03.080 --> 0:40:07.440
<v Speaker 1>our managers have been underweight energy and um, I know

0:40:07.560 --> 0:40:11.560
<v Speaker 1>that's a relatively small um part of the benchmarks now,

0:40:11.640 --> 0:40:16.840
<v Speaker 1>but it has been an industry that has been challenged. Um,

0:40:17.120 --> 0:40:19.160
<v Speaker 1>you know for a lot of different reasons. Stiller worst

0:40:19.200 --> 0:40:23.680
<v Speaker 1>performing group this year. Down, it's just been slammed. Yes,

0:40:23.880 --> 0:40:26.880
<v Speaker 1>although you know you've seen this strong resurgence of the

0:40:26.960 --> 0:40:29.120
<v Speaker 1>last couple of weeks, right, so you know you might

0:40:29.160 --> 0:40:32.120
<v Speaker 1>miss out on on some of these surges, on these

0:40:32.160 --> 0:40:36.000
<v Speaker 1>mild memorillies. And then we have been our managers across

0:40:36.000 --> 0:40:39.520
<v Speaker 1>the board have also been underweight banks because of the

0:40:39.560 --> 0:40:43.440
<v Speaker 1>interest rate pressures that will likely continue. And Miletti always

0:40:43.440 --> 0:40:45.360
<v Speaker 1>good to hear your voice, take care of stay safe.

0:40:45.400 --> 0:40:48.520
<v Speaker 1>And Milletti, head of Active Equity Wells Fargo Asset Management,

0:40:48.960 --> 0:40:52.040
<v Speaker 1>on the phone from Milwaukee. They've got about six hundred

0:40:52.120 --> 0:40:54.840
<v Speaker 1>seven billion in assets under management. Thanks so much for

0:40:54.880 --> 0:40:58.719
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0:40:58.840 --> 0:41:00.960
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0:41:00.960 --> 0:41:03.279
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0:41:03.360 --> 0:41:05.799
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